Planaria EST Database


DrC_01542

BLASTX 2.2.13 [Nov-27-2005]

Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= DrC_01542
         (695 letters)

Database: Non-redundant SwissProt sequences 
           184,735 sequences; 68,354,980 total letters



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

sp|P70196|TRAF6_MOUSE  TNF receptor-associated factor 6            52   1e-06
sp|Q9Y4K3|TRAF6_HUMAN  TNF receptor-associated factor 6 (Int...    51   3e-06
sp|Q8N448|LNX2_HUMAN  Ligand of Numb-protein X 2 (Numb-bindi...    51   3e-06
sp|Q91XL2|LNX2_MOUSE  Ligand of Numb-protein X 2 (Numb-bindi...    49   1e-05
sp|Q8TBB1|LNX1_HUMAN  Ubiquitin ligase LNX (Numb-binding pro...    49   1e-05
sp|O70263|LNX1_MOUSE  Ubiquitin ligase LNX (Numb-binding pro...    49   1e-05
sp|P68907|PZRN3_RAT  PDZ domain-containing RING finger prote...    43   0.001
sp|Q61382|TRAF4_MOUSE  TNF receptor-associated factor 4 (Cys...    42   0.002
sp|Q69ZS0|PZRN3_MOUSE  PDZ domain-containing RING finger pro...    42   0.002
sp|Q9UPQ7|PZRN3_HUMAN  PDZ domain-containing RING finger pro...    41   0.003
>sp|P70196|TRAF6_MOUSE TNF receptor-associated factor 6
          Length = 530

 Score = 52.4 bits (124), Expect = 1e-06
 Identities = 32/127 (25%), Positives = 53/127 (41%), Gaps = 4/127 (3%)
 Frame = +2

Query: 242 INNDFVCNICNKLMVKACNAPCGCKYCSECIENYLHGKDKFCPGKDKFRQMKMINFEKDV 421
           + + + C IC   + +A   PCG ++C  CI   +      CP  ++      I  E  +
Sbjct: 64  LESKYECPICLMALREAVQTPCGHRFCKACIIKSIRDAGHKCPVDNE------ILLENQL 117

Query: 422 SINHQTNRRIAEIVVKCSNKNCKFTDELSSMGNHARTCNKNPTSCPY----FEMGCKNDE 589
             ++   R I  + VKC NK C    EL  + +H   C     +CP     F+    N  
Sbjct: 118 FPDNFAKREILSLTVKCPNKGCLQKMELRHLEDHQVHCEFALVNCPQCQRPFQKCQVNTH 177

Query: 590 VMNDDPK 610
           ++ D P+
Sbjct: 178 IIEDCPR 184
>sp|Q9Y4K3|TRAF6_HUMAN TNF receptor-associated factor 6 (Interleukin 1 signal transducer)
           (RING finger protein 85)
          Length = 522

 Score = 51.2 bits (121), Expect = 3e-06
 Identities = 31/127 (24%), Positives = 53/127 (41%), Gaps = 4/127 (3%)
 Frame = +2

Query: 242 INNDFVCNICNKLMVKACNAPCGCKYCSECIENYLHGKDKFCPGKDKFRQMKMINFEKDV 421
           + + + C IC   + +A   PCG ++C  CI   +      CP  ++      I  E  +
Sbjct: 64  LESKYECPICLMALREAVQTPCGHRFCKACIIKSIRDAGHKCPVDNE------ILLENQL 117

Query: 422 SINHQTNRRIAEIVVKCSNKNCKFTDELSSMGNHARTCNKNPTSCPY----FEMGCKNDE 589
             ++   R I  ++VKC N+ C    EL  + +H   C      CP     F+    N  
Sbjct: 118 FPDNFAKREILSLMVKCPNEGCLHKMELRHLEDHQAHCEFALMDCPQCQRPFQKFHINIH 177

Query: 590 VMNDDPK 610
           ++ D P+
Sbjct: 178 ILKDCPR 184
>sp|Q8N448|LNX2_HUMAN Ligand of Numb-protein X 2 (Numb-binding protein 2) (PDZ
           domain-containing RING finger protein 1)
          Length = 690

 Score = 51.2 bits (121), Expect = 3e-06
 Identities = 22/54 (40%), Positives = 36/54 (66%), Gaps = 1/54 (1%)
 Frame = +2

Query: 212 RENK-FQLINEINNDFVCNICNKLMVKACNAPCGCKYCSECIENYLHGKDKFCP 370
           REN  +   NE+++D VC+IC + +++  + PCG  +C +C+ N+L  KD FCP
Sbjct: 33  RENHLYNYQNEVDDDLVCHICLQPLLQPLDTPCGHTFCYKCLRNFLQEKD-FCP 85
>sp|Q91XL2|LNX2_MOUSE Ligand of Numb-protein X 2 (Numb-binding protein 2)
          Length = 687

 Score = 49.3 bits (116), Expect = 1e-05
 Identities = 21/54 (38%), Positives = 35/54 (64%), Gaps = 1/54 (1%)
 Frame = +2

Query: 212 RENK-FQLINEINNDFVCNICNKLMVKACNAPCGCKYCSECIENYLHGKDKFCP 370
           REN  +    E+++D VC+IC + +++  + PCG  +C +C+ N+L  KD FCP
Sbjct: 34  RENHLYNYQGEVDDDLVCHICLQPLLQPLDTPCGHTFCHKCLRNFLQEKD-FCP 86
>sp|Q8TBB1|LNX1_HUMAN Ubiquitin ligase LNX (Numb-binding protein 1) (Ligand of
           Numb-protein X 1)
          Length = 728

 Score = 48.9 bits (115), Expect = 1e-05
 Identities = 32/113 (28%), Positives = 59/113 (52%), Gaps = 2/113 (1%)
 Frame = +2

Query: 209 IRENKFQLI-NEINNDFVCNICNKLMVKACNAPCGCKYCSECIENYLHGKDKFCPGKDKF 385
           + EN F     E+++D +C+IC + ++   + PCG  YC+ C+ N+L  KD FCP     
Sbjct: 23  LEENHFYSYPEEVDDDLICHICLQALLDPLDTPCGHTYCTLCLTNFLVEKD-FCP---MD 78

Query: 386 RQMKMINFEKDVSINHQTNRRIAEIVVKCS-NKNCKFTDELSSMGNHARTCNK 541
           R+  ++   K  SI    N+ + +++V C   ++C    +   + +H +T  K
Sbjct: 79  RKPLVLQHCKKSSI--LVNKLLNKLLVTCPFREHCTQVLQRCDLEHHFQTSCK 129
>sp|O70263|LNX1_MOUSE Ubiquitin ligase LNX (Numb-binding protein 1) (Ligand of
           Numb-binding protein 1) (Ligand of Numb-protein X 1)
          Length = 728

 Score = 48.9 bits (115), Expect = 1e-05
 Identities = 35/118 (29%), Positives = 53/118 (44%), Gaps = 4/118 (3%)
 Frame = +2

Query: 215 ENKFQLINE-INNDFVCNICNKLMVKACNAPCGCKYCSECIENYLHGKDKFCPGKDKFRQ 391
           EN F    E +++D +C+IC + ++   + PCG  YC+ C+ N+L  KD FCP       
Sbjct: 29  ENHFYTYTEDVDDDLICHICLQALLDPLDTPCGHTYCTLCLTNFLVEKD-FCPVD----- 82

Query: 392 MKMINFEKDVSINHQTNRRIAEIVVKCSNK---NCKFTDELSSMGNHARTCNKNPTSC 556
                  K V + H     I  +V K  NK    C FT+  + +       +   TSC
Sbjct: 83  ------RKPVVLQHCKKSSI--LVNKLLNKLLVTCPFTEHCTEVLQRCDLQHHFQTSC 132
>sp|P68907|PZRN3_RAT PDZ domain-containing RING finger protein 3 (Semaphorin cytoplasmic
           domain-associated protein 3) (SEMACAP3 protein)
          Length = 1062

 Score = 42.7 bits (99), Expect = 0.001
 Identities = 25/114 (21%), Positives = 53/114 (46%), Gaps = 2/114 (1%)
 Frame = +2

Query: 239 EINNDFVCNICNKLMVKACNAPCGCKYCSECIENYLHGKDKFCPGKDKFRQMKMINFEKD 418
           E++ D  C +C+K++      PCG  +C+ C+  ++  ++  CP + + R        K+
Sbjct: 11  EVDPDLKCALCHKVLEDPLTTPCGHVFCAGCVLPWV-VQEGSCPSRCRGRLS-----AKE 64

Query: 419 VSINHQTNRRIAEIVVKCSN--KNCKFTDELSSMGNHARTCNKNPTSCPYFEMG 574
           ++      R I ++ +KC++  + C    +L  +  H   C+  P  C +   G
Sbjct: 65  LNHVLPLKRLILKLDIKCAHAARGCGRVVKLQDLPEHLERCDFAPARCRHAGCG 118
>sp|Q61382|TRAF4_MOUSE TNF receptor-associated factor 4 (Cysteine-rich motif associated to
           RING and Traf domains protein 1)
          Length = 470

 Score = 41.6 bits (96), Expect = 0.002
 Identities = 23/104 (22%), Positives = 46/104 (44%), Gaps = 3/104 (2%)
 Frame = +2

Query: 257 VCNICNKLMVKACN-APCGCKYCSECIENYLHGKDKFCPGKDKFRQMKMINFEKDVSINH 433
           +C +C K M  +   + CG +YC  C++ +L      CP          I  + ++ +  
Sbjct: 17  LCPLCGKPMRDSVEVSTCGHRYCDNCLQEFLSEGVFKCPEDQLPLDYAKIYPDPELEV-- 74

Query: 434 QTNRRIAEIVVKC--SNKNCKFTDELSSMGNHARTCNKNPTSCP 559
               ++  + ++C  S + C+++  L  +  H  TC+ N   CP
Sbjct: 75  ----QVLGLAIRCIHSEEGCRWSGPLRHLQGHLNTCSFNVVPCP 114
>sp|Q69ZS0|PZRN3_MOUSE PDZ domain-containing RING finger protein 3 (Semaphorin cytoplasmic
           domain-associated protein 3) (SEMACAP3 protein)
          Length = 1063

 Score = 41.6 bits (96), Expect = 0.002
 Identities = 24/114 (21%), Positives = 53/114 (46%), Gaps = 2/114 (1%)
 Frame = +2

Query: 239 EINNDFVCNICNKLMVKACNAPCGCKYCSECIENYLHGKDKFCPGKDKFRQMKMINFEKD 418
           +++ D  C +C+K++      PCG  +C+ C+  ++  ++  CP + + R        K+
Sbjct: 11  DVDPDLKCALCHKVLEDPLTTPCGHVFCAGCVLPWV-VQEGSCPARCRGRLS-----AKE 64

Query: 419 VSINHQTNRRIAEIVVKCSN--KNCKFTDELSSMGNHARTCNKNPTSCPYFEMG 574
           ++      R I ++ +KC++  + C    +L  +  H   C+  P  C +   G
Sbjct: 65  LNHVLPLKRLILKLDIKCAHAARGCGRVVKLQDLPEHLERCDFAPARCRHAGCG 118
>sp|Q9UPQ7|PZRN3_HUMAN PDZ domain-containing RING finger protein 3 (Ligand of Numb-protein
           X 3) (Semaphorin cytoplasmic domain-associated protein
           3) (SEMACAP3 protein)
          Length = 1066

 Score = 41.2 bits (95), Expect = 0.003
 Identities = 24/114 (21%), Positives = 52/114 (45%), Gaps = 2/114 (1%)
 Frame = +2

Query: 239 EINNDFVCNICNKLMVKACNAPCGCKYCSECIENYLHGKDKFCPGKDKFRQMKMINFEKD 418
           +++ D  C +C+K++      PCG  +C+ C+  ++  ++  CP + + R        K+
Sbjct: 11  DVDPDLKCALCHKVLEDPLTTPCGHVFCAGCVLPWV-VQEGSCPARCRGRLS-----AKE 64

Query: 419 VSINHQTNRRIAEIVVKC--SNKNCKFTDELSSMGNHARTCNKNPTSCPYFEMG 574
           ++      R I ++ +KC  + + C    +L  +  H   C+  P  C +   G
Sbjct: 65  LNHVLPLKRLILKLDIKCAYATRGCGRVVKLQQLPEHLERCDFAPARCRHAGCG 118
  Database: Non-redundant SwissProt sequences
    Posted date:  Dec 6, 2005  7:40 AM
  Number of letters in database: 68,354,980
  Number of sequences in database:  184,735
  
  Database: swissprot.01
    Posted date:  Dec 6, 2005  8:18 AM
  Number of letters in database: 66,202,850
  Number of sequences in database:  184,431
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 65,477,868
Number of Sequences: 369166
Number of extensions: 1254267
Number of successful extensions: 3526
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 3374
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3515
length of database: 68,354,980
effective HSP length: 107
effective length of database: 48,588,335
effective search space used: 6024953540
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)