Planaria EST Database


DrC_01523

BLASTX 2.2.13 [Nov-27-2005]

Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= DrC_01523
         (937 letters)

Database: Non-redundant SwissProt sequences 
           184,735 sequences; 68,354,980 total letters



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

sp|Q24020|FLII_DROME  Flightless-I protein                        275   1e-73
sp|Q13045|FLII_HUMAN  Flightless-I protein homolog                236   5e-62
sp|Q9JJ28|FLII_MOUSE  Flightless I protein homolog                234   3e-61
sp|P34268|FLII_CAEEL  Flightless-I protein homolog                208   2e-53
sp|Q6UWE0|LRSM1_HUMAN  Ubiquitin ligase protein LRSAM1 (Leuc...    59   3e-08
sp|Q96RT1|LAP2_HUMAN  LAP2 protein (Erbb2-interacting protei...    57   7e-08
sp|P10733|SEVE_DICDI  Severin                                      57   1e-07
sp|Q9V780|LAP1_DROME  Lap1 protein                                 57   1e-07
sp|Q01730|RSU1_MOUSE  Ras suppressor protein 1 (Rsu-1) (RSP-1)     56   1e-07
sp|Q15404|RSU1_HUMAN  Ras suppressor protein 1 (Rsu-1) (RSP-1)     56   1e-07
>sp|Q24020|FLII_DROME Flightless-I protein
          Length = 1256

 Score =  275 bits (704), Expect = 1e-73
 Identities = 154/315 (48%), Positives = 201/315 (63%), Gaps = 4/315 (1%)
 Frame = +3

Query: 3    ELSGLVDCWPNLEVXXXXXXXXXXXXXFITRLSKLKKLYVDENNLTFNGIPPGIGKLTNL 182
            EL+  V+ W  LE               + +L KL++L V++N L F GIP GIGKL  L
Sbjct: 256  ELTAGVELWQRLESLNLSRNQLVALPAALCKLPKLRRLLVNDNKLNFEGIPSGIGKLGAL 315

Query: 183  EVFSASENLLENIPEGLCRCGQLKHLNLKMNKLVTLPDAINVLIESLKTFNIENNPHLKM 362
            EVFSA+ NLLE +PEGLCRCG LK LNL  N+L+TLPDAI+ L+E L   ++ NNP L M
Sbjct: 316  EVFSAANNLLEMVPEGLCRCGALKQLNLSCNRLITLPDAIH-LLEGLDQLDLRNNPELVM 374

Query: 363  PPKLEENDSKSKYSFYNIDFSLETQMQLARGAPVKTSVQNVTQKDTASRIRRLRRKKIDE 542
            PPK  E    +   FYNIDFSL+TQ++LA  A   +   + T KD+ +R  RLRR    E
Sbjct: 375  PPKPSEASKATSLEFYNIDFSLQTQLRLAGAAVPPSMPSSATPKDSTARKIRLRRGPRSE 434

Query: 543  KNEKSDSKRVLEGMQKVAKDKD----AVMEDQEKETIKSAKRWQDAIAKPNLDYSRVFDD 710
             ++  D+ +VL+GM+ VAKDKD    AV ED + E++K  KRW +++ KP LDYS+ F+ 
Sbjct: 435  GDQ--DAAKVLKGMKDVAKDKDNEAGAVPEDGKPESLK-PKRWDESLEKPQLDYSKFFEK 491

Query: 711  DIGTEPGIEIWDIDEFYPRKITEEVPVGTFYNGDCYIILHTRQDEKNHNSLIHSIYYWIG 890
            D G  PG+ IW+I+ F P KI EEV  G FY GDCYI+L T+ D+     L   I++WIG
Sbjct: 492  DDGQLPGLTIWEIENFLPNKI-EEVVHGKFYEGDCYIVLKTKFDDL--GLLDWEIFFWIG 548

Query: 891  NIATLDKVTSAAVHA 935
            N ATLDK   AA+HA
Sbjct: 549  NEATLDKRACAAIHA 563

 Score = 54.7 bits (130), Expect = 4e-07
 Identities = 31/95 (32%), Positives = 50/95 (52%)
 Frame = +3

Query: 87  ITRLSKLKKLYVDENNLTFNGIPPGIGKLTNLEVFSASENLLENIPEGLCRCGQLKHLNL 266
           +T LS L+ L +  N L  +GIPP +  L  L     S N L+ +PEGL R   L  LNL
Sbjct: 71  LTELSCLRSLDLRHNQLKNSGIPPELFHLEELTTLDLSHNKLKEVPEGLERAKNLIVLNL 130

Query: 267 KMNKLVTLPDAINVLIESLKTFNIENNPHLKMPPK 371
             N++ ++P  + + +  L   ++ +N    +PP+
Sbjct: 131 SNNQIESIPTPLFIHLTDLLFLDLSHNRLETLPPQ 165
>sp|Q13045|FLII_HUMAN Flightless-I protein homolog
          Length = 1269

 Score =  236 bits (603), Expect = 5e-62
 Identities = 136/316 (43%), Positives = 185/316 (58%), Gaps = 5/316 (1%)
 Frame = +3

Query: 3    ELSGLVDCWPNLEVXXXXXXXXXXXXXFITRLSKLKKLYVDENNLTFNGIPPGIGKLTNL 182
            ELS  +D W ++E               I +LSKLKKLY++ N L F+G+P GIGKLTNL
Sbjct: 260  ELSLCIDQWVHVETLNLSRNQLTSLPSAICKLSKLKKLYLNSNKLDFDGLPSGIGKLTNL 319

Query: 183  EVFSASENLLENIPEGLCRCGQLKHLNLKMNKLVTLPDAINVLIESLKTFNIENNPHLKM 362
            E F A+ N LE +PE LCRC +L+ L L  N LVTLP+AI+ L E ++  ++  NP+L M
Sbjct: 320  EEFMAANNNLELVPESLCRCPKLRKLVLNKNHLVTLPEAIHFLTE-IEVLDVRENPNLVM 378

Query: 363  PPKLEENDSKSKYSFYNIDFSLETQMQLARGAPVKTSVQNVT---QKDTASRIRRLRRKK 533
            PPK  +  ++    +YNIDFSL+ Q++LA  +P   +         KD  +R  RLRR+K
Sbjct: 379  PPKPADRAAE----WYNIDFSLQNQLRLAGASPATVAAAAAAGSGPKDPMARKMRLRRRK 434

Query: 534  IDEKNEKSDSKRVLEGMQKVAKDKDAVMEDQEKETIKSAK--RWQDAIAKPNLDYSRVFD 707
              +  +   +K+VL+GM  VA++K+   E+       S K  RW   + KP LDYS  F 
Sbjct: 435  --DSAQDDQAKQVLKGMSDVAQEKNKKQEESADARAPSGKVRRWDQGLEKPRLDYSEFFT 492

Query: 708  DDIGTEPGIEIWDIDEFYPRKITEEVPVGTFYNGDCYIILHTRQDEKNHNSLIHSIYYWI 887
            +D+G  PG+ IW I+ F P  + EE   G FY  DCYI+L T  D+    SL   IYYWI
Sbjct: 493  EDVGQLPGLTIWQIENFVP-VLVEEAFHGKFYEADCYIVLKTFLDDS--GSLNWEIYYWI 549

Query: 888  GNIATLDKVTSAAVHA 935
            G  ATLDK   +A+HA
Sbjct: 550  GGEATLDKKACSAIHA 565

 Score = 46.2 bits (108), Expect = 1e-04
 Identities = 26/96 (27%), Positives = 46/96 (47%)
 Frame = +3

Query: 87  ITRLSKLKKLYVDENNLTFNGIPPGIGKLTNLEVFSASENLLENIPEGLCRCGQLKHLNL 266
           ++ L  L+ +    N+L  +G+P  I KL +L V   S N L   P  L     +  LNL
Sbjct: 75  LSSLPSLRAIVARANSLKNSGVPDDIFKLDDLSVLDLSHNQLTECpreLENAKNMLVLNL 134

Query: 267 KMNKLVTLPDAINVLIESLKTFNIENNPHLKMPPKL 374
             N + T+P+ + + +  L   ++  N    +PP++
Sbjct: 135 SHNSIDTIPNQLFINLTDLLYLDLSENRLESLPPQM 170

 Score = 37.4 bits (85), Expect = 0.061
 Identities = 24/90 (26%), Positives = 43/90 (47%)
 Frame = +3

Query: 96  LSKLKKLYVDENNLTFNGIPPGIGKLTNLEVFSASENLLENIPEGLCRCGQLKHLNLKMN 275
           ++ L+ L++     T + +P  +  L+NL     S N L  +PE L     L+ LNL  N
Sbjct: 197 MTALQTLHLRSTQRTQSNLPTSLEGLSNLADVDLSCNDLTRVPECLYTLPSLRRLNLSSN 256

Query: 276 KLVTLPDAINVLIESLKTFNIENNPHLKMP 365
           ++  L   I+  +  ++T N+  N    +P
Sbjct: 257 QITELSLCIDQWVH-VETLNLSRNQLTSLP 285
>sp|Q9JJ28|FLII_MOUSE Flightless I protein homolog
          Length = 1271

 Score =  234 bits (596), Expect = 3e-61
 Identities = 136/316 (43%), Positives = 184/316 (58%), Gaps = 5/316 (1%)
 Frame = +3

Query: 3    ELSGLVDCWPNLEVXXXXXXXXXXXXXFITRLSKLKKLYVDENNLTFNGIPPGIGKLTNL 182
            ELS  +D W +LE               I +L+KLKKLY++ N L F+G+P GIGKLT+L
Sbjct: 260  ELSLCIDQWVHLETLNLSRNQLTSLPSAICKLTKLKKLYLNSNKLDFDGLPSGIGKLTSL 319

Query: 183  EVFSASENLLENIPEGLCRCGQLKHLNLKMNKLVTLPDAINVLIESLKTFNIENNPHLKM 362
            E F A+ N LE IPE LCRC +LK L L  N+LVTLP+AI+ L E ++  ++  NP L M
Sbjct: 320  EEFMAANNNLELIPESLCRCPKLKKLVLNKNRLVTLPEAIHFLTE-IQVLDVRENPSLVM 378

Query: 363  PPKLEENDSKSKYSFYNIDFSLETQMQLARGAPVKTSVQNVT---QKDTASRIRRLRRKK 533
            PPK  +  ++    +YNIDFSL+ Q++LA  +P   +         KD  +R  RLRR+K
Sbjct: 379  PPKPADRTAE----WYNIDFSLQNQLRLAGASPATVAAAAAVGSGSKDPLARKMRLRRRK 434

Query: 534  IDEKNEKSDSKRVLEGMQKVAKDKDAVMEDQEKETIKSAK--RWQDAIAKPNLDYSRVFD 707
              +  +   +K+VL+GM  VA++K+   E+         K  RW   + KP LDYS  F 
Sbjct: 435  --DSAQDVQAKQVLKGMSDVAQEKNKNQEESIDARAPGGKVRRWDQGLEKPRLDYSEFFT 492

Query: 708  DDIGTEPGIEIWDIDEFYPRKITEEVPVGTFYNGDCYIILHTRQDEKNHNSLIHSIYYWI 887
            +D+G  PG+ IW I+ F P  + EE   G FY  DCYI+L T  D+    SL   IYYWI
Sbjct: 493  EDVGQLPGLTIWQIENFVP-VLVEEAFHGKFYEADCYIVLKTFLDDS--GSLNWEIYYWI 549

Query: 888  GNIATLDKVTSAAVHA 935
            G  ATLDK   +A+HA
Sbjct: 550  GGEATLDKKACSAIHA 565

 Score = 43.9 bits (102), Expect = 7e-04
 Identities = 25/96 (26%), Positives = 46/96 (47%)
 Frame = +3

Query: 87  ITRLSKLKKLYVDENNLTFNGIPPGIGKLTNLEVFSASENLLENIPEGLCRCGQLKHLNL 266
           ++ L  L+ +    N+L  +G+P  I KL +L V   S N L   P  L     +  LNL
Sbjct: 75  LSSLPSLRAIVARANSLKNSGVPDDIFKLDDLSVLDLSHNQLTECpreLENAKNMLVLNL 134

Query: 267 KMNKLVTLPDAINVLIESLKTFNIENNPHLKMPPKL 374
             N + ++P+ + + +  L   ++  N    +PP++
Sbjct: 135 SHNGIDSIPNQLFINLTDLLYLDLSENRLESLPPQM 170

 Score = 38.1 bits (87), Expect = 0.036
 Identities = 25/87 (28%), Positives = 41/87 (47%)
 Frame = +3

Query: 105 LKKLYVDENNLTFNGIPPGIGKLTNLEVFSASENLLENIPEGLCRCGQLKHLNLKMNKLV 284
           L+ L++     T + +P  +  L+NL     S N L  +PE L     L+ LNL  N++ 
Sbjct: 200 LQTLHLRNTQRTQSNLPTSLEGLSNLSDVDLSCNDLTRVPECLYTLPSLRRLNLSSNQIA 259

Query: 285 TLPDAINVLIESLKTFNIENNPHLKMP 365
            L   I+  +  L+T N+  N    +P
Sbjct: 260 ELSLCIDQWVH-LETLNLSRNQLTSLP 285
>sp|P34268|FLII_CAEEL Flightless-I protein homolog
          Length = 1257

 Score =  208 bits (530), Expect = 2e-53
 Identities = 122/315 (38%), Positives = 186/315 (59%), Gaps = 12/315 (3%)
 Frame = +3

Query: 27   WPNLEVXXXXXXXXXXXXXFITRLSKLKKLYVDENNLTFNGIPPGIGKLTNLEVFSASEN 206
            W NLE               + +L++L KLY   N LTF GIP GIGKL  L V   S N
Sbjct: 267  WENLETLNMSHNQLTVLPDCVVKLTRLTKLYAANNQLTFEGIPSGIGKLIQLTVLHLSYN 326

Query: 207  LLENIPEGLCRCGQLKHLNLKMNKLVTLPDAINVLIESLKTFNIENNPHLKMPPKLEEND 386
             LE +PEG+ RC +L+ L L  N+L+TLP+ I+ L+  LK  ++  N +L MPPK   ND
Sbjct: 327  KLELVPEGISRCVKLQKLKLDHNRLITLPEGIH-LLPDLKVLDLHENENLVMPPK--PND 383

Query: 387  SKSKYSFYNIDFSLETQMQLA-RGAPVKTSVQNV----TQKDTASRIRRLRRKKIDEKNE 551
            ++ K +FYNIDFSLE Q ++A +     +S+ +V     ++D  +R +   R++  + ++
Sbjct: 384  ARKKLAFYNIDFSLEHQRKIAGQMTSPSSSISSVHSGGARQDALARRKEFIRRRKQQADQ 443

Query: 552  KSDSKRVLEGMQKVAKDKDAVMEDQEKE-----TIKSAKRWQDAIAK--PNLDYSRVFDD 710
            +S  K V++GM K+A    A+ E Q++E       KSA  W+  I K   ++DYS +FD+
Sbjct: 444  QSADK-VIQGMSKIAGVGAALTEKQQEEEERQLEAKSAVNWKKNIEKNRRHIDYSDIFDE 502

Query: 711  DIGTEPGIEIWDIDEFYPRKITEEVPVGTFYNGDCYIILHTRQDEKNHNSLIHSIYYWIG 890
            D+G++ G+ +W+I+ FYP  I +E   G FY+ D Y++L T ++      L H+I+YW+G
Sbjct: 503  DVGSDEGMWVWEIENFYP-SIMDEAFHGQFYDADAYLVLKTTREAS--GQLRHAIFYWLG 559

Query: 891  NIATLDKVTSAAVHA 935
              A+LDK   +AVHA
Sbjct: 560  EHASLDKGMCSAVHA 574

 Score = 48.9 bits (115), Expect = 2e-05
 Identities = 27/96 (28%), Positives = 49/96 (51%)
 Frame = +3

Query: 87  ITRLSKLKKLYVDENNLTFNGIPPGIGKLTNLEVFSASENLLENIPEGLCRCGQLKHLNL 266
           ++ L +L+ + V +NNL   GIP  I ++ +L +   S N L  +P  L        LNL
Sbjct: 74  LSDLPRLRSVIVRDNNLKTAGIPTDIFRMKDLTIIDLSRNQLREVPTNLEYAKGSIVLNL 133

Query: 267 KMNKLVTLPDAINVLIESLKTFNIENNPHLKMPPKL 374
             N + T+P+++   +  L   ++ NN    +PP++
Sbjct: 134 SYNNIETIPNSVCANLIDLLFLDLSNNKLDMLPPQI 169

 Score = 47.0 bits (110), Expect = 8e-05
 Identities = 29/90 (32%), Positives = 46/90 (51%)
 Frame = +3

Query: 96  LSKLKKLYVDENNLTFNGIPPGIGKLTNLEVFSASENLLENIPEGLCRCGQLKHLNLKMN 275
           ++ L  L++   N T + IPP +  + NL     SEN L  +PE L +   L+ LNL  N
Sbjct: 196 MTSLSVLHMSNTNRTLDNIPPTLDDMHNLRDVDFSENNLPIVPEALFKLRNLRKLNLSGN 255

Query: 276 KLVTLPDAINVLIESLKTFNIENNPHLKMP 365
           K+  L +      E+L+T N+ +N    +P
Sbjct: 256 KIEKL-NMTEGEWENLETLNMSHNQLTVLP 284

 Score = 37.7 bits (86), Expect = 0.047
 Identities = 19/84 (22%), Positives = 42/84 (50%)
 Frame = +3

Query: 96  LSKLKKLYVDENNLTFNGIPPGIGKLTNLEVFSASENLLENIPEGLCRCGQLKHLNLKMN 275
           L  +K +    N+ + +  P  + ++T +     +++ LE +P+ L RC  L+HL +  N
Sbjct: 6   LQFVKGIDFSGNDFSGDRFPHDVEQMTQMTWLKLNDSKLEQVPDELSRCANLEHLQMAHN 65

Query: 276 KLVTLPDAINVLIESLKTFNIENN 347
           +L+++   ++ L         +NN
Sbjct: 66  QLISVHGELSDLPRLRSVIVRDNN 89
>sp|Q6UWE0|LRSM1_HUMAN Ubiquitin ligase protein LRSAM1 (Leucine-rich repeat and sterile
           alpha motif containing 1) (Tsg101-associated ligase)
           (hTAL)
          Length = 723

 Score = 58.5 bits (140), Expect = 3e-08
 Identities = 35/93 (37%), Positives = 52/93 (55%)
 Frame = +3

Query: 96  LSKLKKLYVDENNLTFNGIPPGIGKLTNLEVFSASENLLENIPEGLCRCGQLKHLNLKMN 275
           L+ +K L + +N LT   +P  +G+LT L+V +   N L  +P  +    QL+ LN+K N
Sbjct: 80  LATIKVLDLHDNQLT--ALPDDLGQLTALQVLNVERNQLMQLPRSIGNLTQLQTLNVKDN 137

Query: 276 KLVTLPDAINVLIESLKTFNIENNPHLKMPPKL 374
           KL  LPD +  L  SL+T NI  N   ++P  L
Sbjct: 138 KLKELPDTVGEL-RSLRTLNISGNEIQRLPQML 169
>sp|Q96RT1|LAP2_HUMAN LAP2 protein (Erbb2-interacting protein) (Erbin) (Densin-180-like
           protein)
          Length = 1412

 Score = 57.0 bits (136), Expect = 7e-08
 Identities = 34/96 (35%), Positives = 52/96 (54%)
 Frame = +3

Query: 87  ITRLSKLKKLYVDENNLTFNGIPPGIGKLTNLEVFSASENLLENIPEGLCRCGQLKHLNL 266
           + +LS LK+ ++D N LTF  IP  IG L  L     S+N +E + EG+  C  L+ L L
Sbjct: 203 LEQLSGLKEFWMDANRLTF--IPGFIGSLKQLTYLDVSKNNIEMVEEGISTCENLQDLLL 260

Query: 267 KMNKLVTLPDAINVLIESLKTFNIENNPHLKMPPKL 374
             N L  LP+ I  L +++ T  I+ N  + +P  +
Sbjct: 261 SSNSLQQLPETIGSL-KNITTLKIDENQLMYLPDSI 295

 Score = 48.5 bits (114), Expect = 3e-05
 Identities = 29/85 (34%), Positives = 46/85 (54%), Gaps = 3/85 (3%)
 Frame = +3

Query: 120 VDENNLTFN---GIPPGIGKLTNLEVFSASENLLENIPEGLCRCGQLKHLNLKMNKLVTL 290
           V+E + +FN    +P  IG+LTNL  F+A  N L+ +P  +     +  L L  NKL TL
Sbjct: 301 VEELDCSFNEVEALPSSIGQLTNLRTFAADHNYLQQLPPEIGSWKNITVLFLHSNKLETL 360

Query: 291 PDAINVLIESLKTFNIENNPHLKMP 365
           P+ +  + + LK  N+ +N    +P
Sbjct: 361 PEEMGDM-QKLKVINLSDNRLKNLP 384

 Score = 46.2 bits (108), Expect = 1e-04
 Identities = 32/104 (30%), Positives = 51/104 (49%)
 Frame = +3

Query: 87  ITRLSKLKKLYVDENNLTFNGIPPGIGKLTNLEVFSASENLLENIPEGLCRCGQLKHLNL 266
           I +L+ L+    D N L    +PP IG   N+ V     N LE +PE +    +LK +NL
Sbjct: 318 IGQLTNLRTFAADHNYL--QQLPPEIGSWKNITVLFLHSNKLETLPEEMGDMQKLKVINL 375

Query: 267 KMNKLVTLPDAINVLIESLKTFNIENNPHLKMPPKLEENDSKSK 398
             N+L  LP +   L + L    + +N    + P  +E DS+++
Sbjct: 376 SDNRLKNLPFSFTKL-QQLTAMWLSDNQSKPLIPLQKETDSETQ 418

 Score = 39.3 bits (90), Expect = 0.016
 Identities = 22/70 (31%), Positives = 35/70 (50%)
 Frame = +3

Query: 105 LKKLYVDENNLTFNGIPPGIGKLTNLEVFSASENLLENIPEGLCRCGQLKHLNLKMNKLV 284
           L KL + +N+LT   +P  I  L NL     S+N ++  PE +  C  L  +   +N + 
Sbjct: 71  LHKLSLPDNDLTT--LPASIANLINLRELDVSKNGIQEFPENIKNCKVLTIVEASVNPIS 128

Query: 285 TLPDAINVLI 314
            LPD  + L+
Sbjct: 129 KLPDGFSQLL 138

 Score = 35.8 bits (81), Expect = 0.18
 Identities = 24/73 (32%), Positives = 35/73 (47%)
 Frame = +3

Query: 93  RLSKLKKLYVDENNLTFNGIPPGIGKLTNLEVFSASENLLENIPEGLCRCGQLKHLNLKM 272
           RL+KL+ L + EN L    +P  + +LT LE      N    +PE L +   LK   +  
Sbjct: 159 RLTKLQILELRENQLKM--LPKTMNRLTQLERLDLGSNEFTEVPEVLEQLSGLKEFWMDA 216

Query: 273 NKLVTLPDAINVL 311
           N+L  +P  I  L
Sbjct: 217 NRLTFIPGFIGSL 229
>sp|P10733|SEVE_DICDI Severin
          Length = 362

 Score = 56.6 bits (135), Expect = 1e-07
 Identities = 30/71 (42%), Positives = 42/71 (59%)
 Frame = +3

Query: 714 IGTEPGIEIWDIDEFYPRKITEEVPVGTFYNGDCYIILHTRQDEKNHNSLIHSIYYWIGN 893
           +G  PG++IW I+ F    + E    G FY+GD YIILHT    K  NSL H I++++G 
Sbjct: 39  VGQAPGLKIWRIENFKVVPVPES-SYGKFYDGDSYIILHT---FKEGNSLKHDIHFFLGT 94

Query: 894 IATLDKVTSAA 926
             T D+  +AA
Sbjct: 95  FTTQDEAGTAA 105
>sp|Q9V780|LAP1_DROME Lap1 protein
          Length = 849

 Score = 56.6 bits (135), Expect = 1e-07
 Identities = 31/70 (44%), Positives = 40/70 (57%)
 Frame = +3

Query: 105 LKKLYVDENNLTFNGIPPGIGKLTNLEVFSASENLLENIPEGLCRCGQLKHLNLKMNKLV 284
           L+ L+V+ NNL    IP  IG L  L+    + NL+ N+PE +  C  L HL+L  N L 
Sbjct: 65  LRVLHVNSNNL--ESIPQAIGSLRQLQHLDLNRNLIVNVPEEIKSCKHLTHLDLSCNSLQ 122

Query: 285 TLPDAINVLI 314
            LPDAI  LI
Sbjct: 123 RLPDAITSLI 132

 Score = 53.1 bits (126), Expect = 1e-06
 Identities = 39/129 (30%), Positives = 60/129 (46%), Gaps = 11/129 (8%)
 Frame = +3

Query: 87  ITRLSKLKKLYVDENNLTFNGIPPGIGKLTNLEVFSASENLLENIPEGLCRCGQLKHLNL 266
           I+ L +L++L +  N L    +P  IG L +L    A +N L  +P+ LC C QL  L++
Sbjct: 289 ISYLEQLEELVLSHNKLI--RLPSTIGMLRSLRFLFADDNQLRQLPDELCSCQQLSVLSV 346

Query: 267 KMNKLVTLPDAINVLIESLKTFNIENNPHLKMPPK-----------LEENDSKSKYSFYN 413
             N+L  LP  I  L   +K  N+ NN    +P             L +N S+       
Sbjct: 347 ANNQLSALPQNIGNL-SKMKVLNVVNNYINALPVSMLNLVNLTSMWLSDNQSQPLVPLQY 405

Query: 414 IDFSLETQM 440
           +D S +TQ+
Sbjct: 406 LDASTKTQL 414

 Score = 49.3 bits (116), Expect = 2e-05
 Identities = 29/96 (30%), Positives = 53/96 (55%)
 Frame = +3

Query: 87  ITRLSKLKKLYVDENNLTFNGIPPGIGKLTNLEVFSASENLLENIPEGLCRCGQLKHLNL 266
           +  L  L++L++D N +    +   IGKL +L+ F A+ NLL+ +P  L     ++ L++
Sbjct: 197 VGELKSLRELWIDFNQI--RRVSANIGKLRDLQHFEANGNLLDTLPSELSNWRNVEVLSI 254

Query: 267 KMNKLVTLPDAINVLIESLKTFNIENNPHLKMPPKL 374
             N L   P ++ +L +SL TF  E+N   ++P  +
Sbjct: 255 CSNSLEAFPFSVGML-KSLVTFKCESNGLTELPDSI 289

 Score = 41.2 bits (95), Expect = 0.004
 Identities = 22/66 (33%), Positives = 36/66 (54%)
 Frame = +3

Query: 105 LKKLYVDENNLTFNGIPPGIGKLTNLEVFSASENLLENIPEGLCRCGQLKHLNLKMNKLV 284
           L++LY+    L    +PP +     L V   + N LE+IP+ +    QL+HL+L  N +V
Sbjct: 42  LEELYLSTTRL--QALPPQLFYCQGLRVLHVNSNNLESIPQAIGSLRQLQHLDLNRNLIV 99

Query: 285 TLPDAI 302
            +P+ I
Sbjct: 100 NVPEEI 105
>sp|Q01730|RSU1_MOUSE Ras suppressor protein 1 (Rsu-1) (RSP-1)
          Length = 277

 Score = 56.2 bits (134), Expect = 1e-07
 Identities = 32/87 (36%), Positives = 51/87 (58%), Gaps = 2/87 (2%)
 Frame = +3

Query: 96  LSKLKKLYVDENNLTFNGIPPGIGKLTNLEVFSASENLLENIPEGLCRCGQLKHLNLKMN 275
           L+ L+ LY+ +N+  F  +PP IGKLT L++ S  +N L ++P+ +    QLK L+++ N
Sbjct: 133 LTTLRALYLSDND--FEILPPDIGKLTKLQILSLRDNDLISLPKEIGELTQLKELHIQGN 190

Query: 276 KLVTLPDAIN--VLIESLKTFNIENNP 350
           +L  LP  +    L    + F  ENNP
Sbjct: 191 RLTVLPPELGNLDLTGQKQVFKAENNP 217

 Score = 52.4 bits (124), Expect = 2e-06
 Identities = 27/66 (40%), Positives = 40/66 (60%)
 Frame = +3

Query: 96  LSKLKKLYVDENNLTFNGIPPGIGKLTNLEVFSASENLLENIPEGLCRCGQLKHLNLKMN 275
           L+ + +L +  N LT   +PP + +L NLEV +   N +E +P  +    +LKHLNL MN
Sbjct: 39  LAHITQLVLSHNKLTT--VPPNVAELKNLEVLNFFNNQIEELPTQISSLQKLKHLNLGMN 96

Query: 276 KLVTLP 293
           +L TLP
Sbjct: 97  RLNTLP 102

 Score = 45.8 bits (107), Expect = 2e-04
 Identities = 30/94 (31%), Positives = 49/94 (52%)
 Frame = +3

Query: 105 LKKLYVDENNLTFNGIPPGIGKLTNLEVFSASENLLENIPEGLCRCGQLKHLNLKMNKLV 284
           L+ L +  NNL  + +P     LT L     S+N  E +P  + +  +L+ L+L+ N L+
Sbjct: 111 LEVLELTYNNLNEHSLPGNFFYLTTLRALYLSDNDFEILPPDIGKLTKLQILSLRDNDLI 170

Query: 285 TLPDAINVLIESLKTFNIENNPHLKMPPKLEEND 386
           +LP  I  L + LK  +I+ N    +PP+L   D
Sbjct: 171 SLPKEIGELTQ-LKELHIQGNRLTVLPPELGNLD 203
>sp|Q15404|RSU1_HUMAN Ras suppressor protein 1 (Rsu-1) (RSP-1)
          Length = 277

 Score = 56.2 bits (134), Expect = 1e-07
 Identities = 32/87 (36%), Positives = 51/87 (58%), Gaps = 2/87 (2%)
 Frame = +3

Query: 96  LSKLKKLYVDENNLTFNGIPPGIGKLTNLEVFSASENLLENIPEGLCRCGQLKHLNLKMN 275
           L+ L+ LY+ +N+  F  +PP IGKLT L++ S  +N L ++P+ +    QLK L+++ N
Sbjct: 133 LTTLRALYLSDND--FEILPPDIGKLTKLQILSLRDNDLISLPKEIGELTQLKELHIQGN 190

Query: 276 KLVTLPDAIN--VLIESLKTFNIENNP 350
           +L  LP  +    L    + F  ENNP
Sbjct: 191 RLTVLPPELGNLDLTGQKQVFKAENNP 217

 Score = 54.7 bits (130), Expect = 4e-07
 Identities = 29/66 (43%), Positives = 40/66 (60%)
 Frame = +3

Query: 96  LSKLKKLYVDENNLTFNGIPPGIGKLTNLEVFSASENLLENIPEGLCRCGQLKHLNLKMN 275
           LS + +L +  N LT   +PP I +L NLEV +   N +E +P  +    +LKHLNL MN
Sbjct: 39  LSHITQLVLSHNKLTM--VPPNIAELKNLEVLNFFNNQIEELPTQISSLQKLKHLNLGMN 96

Query: 276 KLVTLP 293
           +L TLP
Sbjct: 97  RLNTLP 102

 Score = 48.5 bits (114), Expect = 3e-05
 Identities = 32/97 (32%), Positives = 51/97 (52%)
 Frame = +3

Query: 96  LSKLKKLYVDENNLTFNGIPPGIGKLTNLEVFSASENLLENIPEGLCRCGQLKHLNLKMN 275
           L  L+ L +  NNL+ N +P     LT L     S+N  E +P  + +  +L+ L+L+ N
Sbjct: 108 LPALEVLDLTYNNLSENSLPGNFFYLTTLRALYLSDNDFEILPPDIGKLTKLQILSLRDN 167

Query: 276 KLVTLPDAINVLIESLKTFNIENNPHLKMPPKLEEND 386
            L++LP  I  L + LK  +I+ N    +PP+L   D
Sbjct: 168 DLISLPKEIGELTQ-LKELHIQGNRLTVLPPELGNLD 203
  Database: Non-redundant SwissProt sequences
    Posted date:  Dec 6, 2005  7:40 AM
  Number of letters in database: 68,354,980
  Number of sequences in database:  184,735
  
  Database: swissprot.01
    Posted date:  Dec 6, 2005  8:18 AM
  Number of letters in database: 66,202,850
  Number of sequences in database:  184,431
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 94,319,483
Number of Sequences: 369166
Number of extensions: 1810851
Number of successful extensions: 6664
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 5884
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 6551
length of database: 68,354,980
effective HSP length: 110
effective length of database: 48,034,130
effective search space used: 9654860130
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)