Planaria EST Database


DrC_01517

BLASTX 2.2.13 [Nov-27-2005]

Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= DrC_01517
         (776 letters)

Database: Non-redundant SwissProt sequences 
           184,735 sequences; 68,354,980 total letters



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

sp|Q9Y4K3|TRAF6_HUMAN  TNF receptor-associated factor 6 (Int...    64   4e-10
sp|P70196|TRAF6_MOUSE  TNF receptor-associated factor 6            61   4e-09
sp|P70191|TRAF5_MOUSE  TNF receptor-associated factor 5            57   7e-08
sp|O00463|TRAF5_HUMAN  TNF receptor-associated factor 5 (RIN...    52   2e-06
sp|P39429|TRAF2_MOUSE  TNF receptor-associated factor 2            51   3e-06
sp|Q12933|TRAF2_HUMAN  TNF receptor-associated factor 2 (Tum...    49   2e-05
sp|Q9BUZ4|TRAF4_HUMAN  TNF receptor-associated factor 4 (Cys...    46   1e-04
sp|Q91187|RAG1_ONCMY  V(D)J recombination-activating protein...    45   2e-04
sp|Q61382|TRAF4_MOUSE  TNF receptor-associated factor 4 (Cys...    45   3e-04
sp|O13033|RAG1_BRARE  V(D)J recombination-activating protein...    44   6e-04
>sp|Q9Y4K3|TRAF6_HUMAN TNF receptor-associated factor 6 (Interleukin 1 signal transducer)
           (RING finger protein 85)
          Length = 522

 Score = 64.3 bits (155), Expect = 4e-10
 Identities = 40/117 (34%), Positives = 61/117 (52%), Gaps = 1/117 (0%)
 Frame = +1

Query: 133 KCVIWKEILVNAQQSLCGCHFCQICI-KNYQNSGSKNCPGNTDECKSENLTNIFPDRGTN 309
           +C I    L  A Q+ CG  FC+ CI K+ +++G K CP + +E   EN   +FPD    
Sbjct: 69  ECPICLMALREAVQTPCGHRFCKACIIKSIRDAGHK-CPVD-NEILLEN--QLFPDNFAK 124

Query: 310 KRISNLIARCPHESCSHECRLIEMEDHMRFCSTRNVNCPFNNVGCEHEEMNIDKLDD 480
           + I +L+ +CP+E C H+  L  +EDH   C    ++CP      +   +NI  L D
Sbjct: 125 REILSLMVKCPNEGCLHKMELRHLEDHQAHCEFALMDCPQCQRPFQKFHINIHILKD 181

 Score = 34.3 bits (77), Expect = 0.39
 Identities = 31/123 (25%), Positives = 53/123 (43%), Gaps = 12/123 (9%)
 Frame = +1

Query: 235 KNCPGNTDECKSENLTNIFPDR---GTNKRISNLIARCPHESCSHECRLIEMEDHMRF-C 402
           K+CP     C +   +  F D+     N  ++N+I     E C+      +M +H    C
Sbjct: 180 KDCPRRQVSCDNCAASMAFEDKEIHDQNCPLANVIC----EYCNTILIREQMPNHYDLDC 235

Query: 403 STRNVNCPFNNVGCEHEEMNIDKLDDHMLLEIVNHNKILIDIIGNLR--------SDVRE 558
            T  + C F+  GC HE+M  + L  H+     +H ++L   + +L         S+VR 
Sbjct: 236 PTAPIPCTFSTFGC-HEKMQRNHLARHLQENTQSHMRMLAQAVHSLSVIPDSGYISEVRN 294

Query: 559 LKE 567
            +E
Sbjct: 295 FQE 297
>sp|P70196|TRAF6_MOUSE TNF receptor-associated factor 6
          Length = 530

 Score = 60.8 bits (146), Expect = 4e-09
 Identities = 36/99 (36%), Positives = 53/99 (53%), Gaps = 1/99 (1%)
 Frame = +1

Query: 133 KCVIWKEILVNAQQSLCGCHFCQICI-KNYQNSGSKNCPGNTDECKSENLTNIFPDRGTN 309
           +C I    L  A Q+ CG  FC+ CI K+ +++G K CP + +E   EN   +FPD    
Sbjct: 69  ECPICLMALREAVQTPCGHRFCKACIIKSIRDAGHK-CPVD-NEILLEN--QLFPDNFAK 124

Query: 310 KRISNLIARCPHESCSHECRLIEMEDHMRFCSTRNVNCP 426
           + I +L  +CP++ C  +  L  +EDH   C    VNCP
Sbjct: 125 REILSLTVKCPNKGCLQKMELRHLEDHQVHCEFALVNCP 163
>sp|P70191|TRAF5_MOUSE TNF receptor-associated factor 5
          Length = 558

 Score = 56.6 bits (135), Expect = 7e-08
 Identities = 34/126 (26%), Positives = 57/126 (45%), Gaps = 2/126 (1%)
 Frame = +1

Query: 97  KFTIINEINEDLKCVIWKEILVNAQQSLCGCHFCQICIKNYQNSGS-KNCPGNTDECKSE 273
           ++  + ++ E  KC     +L N  Q+ CG  FCQ CI++ +   S   CP + +  K +
Sbjct: 32  EYQFVEQLEERYKCAFCHSVLHNPHQTGCGHRFCQQCIRSLRELNSVPICPVDKEVIKPQ 91

Query: 274 NLTNIFPDRGTNKRISNLIARCPH-ESCSHECRLIEMEDHMRFCSTRNVNCPFNNVGCEH 450
               +F D    + + NL   C +   C+    L   +DH++ CS + V CP  N  C  
Sbjct: 92  ---EVFKDNCCKREVLNLHVYCKNAPGCNARIILGRFQDHLQHCSFQAVPCP--NESCRE 146

Query: 451 EEMNID 468
             +  D
Sbjct: 147 AMLRKD 152

 Score = 33.1 bits (74), Expect = 0.87
 Identities = 24/88 (27%), Positives = 36/88 (40%), Gaps = 10/88 (11%)
 Frame = +1

Query: 337 CPHESCSHECRLIEMEDHMRFCSTRNVNCPFNNVGC----------EHEEMNIDKLDDHM 486
           CP+  C        + +H+  C     +CPF + GC          EHE      L DHM
Sbjct: 195 CPNR-CVQTIPRARVNEHLTVCPEAEQDCPFKHYGCTVKGKRGNLLEHERA---ALQDHM 250

Query: 487 LLEIVNHNKILIDIIGNLRSDVRELKEK 570
           LL ++  N  L   I +L   + + + K
Sbjct: 251 LL-VLEKNYQLEQRISDLYQSLEQKESK 277
>sp|O00463|TRAF5_HUMAN TNF receptor-associated factor 5 (RING finger protein 84)
          Length = 557

 Score = 51.6 bits (122), Expect = 2e-06
 Identities = 34/132 (25%), Positives = 60/132 (45%), Gaps = 2/132 (1%)
 Frame = +1

Query: 97  KFTIINEINEDLKCVIWKEILVNAQQSLCGCHFCQICIKNYQNSGS-KNCPGNTDECKSE 273
           ++  +  + E  KC     +L N  Q+ CG  FCQ CI + +   +   CP + +  KS+
Sbjct: 32  EYQFVERLEERYKCAFCHSVLHNPHQTGCGHRFCQHCILSLRELNTVPICPVDKEVIKSQ 91

Query: 274 NLTNIFPDRGTNKRISNLIARCPH-ESCSHECRLIEMEDHMRFCSTRNVNCPFNNVGCEH 450
               +F D    + + NL   C +   C+ +  L   +DH++ C  + V C  +N  C  
Sbjct: 92  ---EVFKDNCCKREVLNLYVYCSNAPGCNAKVILGRYQDHLQQCLFQPVQC--SNEKCRE 146

Query: 451 EEMNIDKLDDHM 486
             +  D L +H+
Sbjct: 147 PVLRKD-LKEHL 157

 Score = 32.3 bits (72), Expect = 1.5
 Identities = 22/88 (25%), Positives = 40/88 (45%), Gaps = 10/88 (11%)
 Frame = +1

Query: 337 CPHESCSHECRLIEMEDHMRFCSTRNVNCPFNNVGC----------EHEEMNIDKLDDHM 486
           CP+ +C+      E+++H+  C     +CPF + GC          +HE      L +HM
Sbjct: 195 CPN-NCAKIILKTEVDEHLAVCPEAEQDCPFKHYGCAVTDKRRNLQQHEH---SALREHM 250

Query: 487 LLEIVNHNKILIDIIGNLRSDVRELKEK 570
            L ++  N  L + I +L   + + + K
Sbjct: 251 RL-VLEKNVQLEEQISDLHKSLEQKESK 277
>sp|P39429|TRAF2_MOUSE TNF receptor-associated factor 2
          Length = 501

 Score = 51.2 bits (121), Expect = 3e-06
 Identities = 31/104 (29%), Positives = 45/104 (43%), Gaps = 7/104 (6%)
 Frame = +1

Query: 136 CVIWKEILVNAQQSLCGCHFCQICIKNYQNSGSKNCPGNTDECKSENLTNI------FPD 297
           C   K IL    Q+ CG  +C  C+ +  +SG +NC     E   E   +I      FPD
Sbjct: 34  CSACKNILRRPFQAQCGHRYCSFCLTSILSSGPQNCAACVYEGLYEEGISILESSSAFPD 93

Query: 298 RGTNKRISNLIARCPHESCSHECRLIEMED-HMRFCSTRNVNCP 426
               + + +L A CP++ C+ +  L E E  H   C      CP
Sbjct: 94  NAARREVESLPAVCPNDGCTWKGTLKEYESCHEGLCPFLLTECP 137
>sp|Q12933|TRAF2_HUMAN TNF receptor-associated factor 2 (Tumor necrosis factor type 2
           receptor-associated protein 3)
          Length = 501

 Score = 48.9 bits (115), Expect = 2e-05
 Identities = 29/104 (27%), Positives = 44/104 (42%), Gaps = 7/104 (6%)
 Frame = +1

Query: 136 CVIWKEILVNAQQSLCGCHFCQICIKNYQNSGSKNCPGNTDECKSENLTNI------FPD 297
           C   + +L    Q+ CG  +C  C+ +  +SG +NC     E   E   +I      FPD
Sbjct: 34  CSACRNVLRRPFQAQCGHRYCSFCLASILSSGPQNCAACVHEGIYEEGISILESSSAFPD 93

Query: 298 RGTNKRISNLIARCPHESCSHECRLIEMED-HMRFCSTRNVNCP 426
               + + +L A CP + C+ +  L E E  H   C      CP
Sbjct: 94  NAARREVESLPAVCPSDGCTWKGTLKEYESCHEGRCPLMLTECP 137
>sp|Q9BUZ4|TRAF4_HUMAN TNF receptor-associated factor 4 (Cysteine-rich domain associated
           with RING and Traf domains protein 1) (Malignant 62)
           (RING finger protein 83)
          Length = 470

 Score = 46.2 bits (108), Expect = 1e-04
 Identities = 25/88 (28%), Positives = 39/88 (44%), Gaps = 2/88 (2%)
 Frame = +1

Query: 169 QQSLCGCHFCQICIKNYQNSGSKNCPGNTDECKSENLTNIFPDRGTNKRISNLIARCPH- 345
           Q S CG  FC  C++ + + G   CP   ++    +   I+PD     ++  L  RC H 
Sbjct: 30  QVSTCGHRFCDTCLQEFLSEGVFKCP---EDQLPLDYAKIYPDPELEVQVLGLPIRCIHS 86

Query: 346 -ESCSHECRLIEMEDHMRFCSTRNVNCP 426
            E C     L  ++ H+  CS   + CP
Sbjct: 87  EEGCRWSGPLRHLQGHLNTCSFNVIPCP 114

 Score = 36.6 bits (83), Expect = 0.079
 Identities = 27/137 (19%), Positives = 59/137 (43%), Gaps = 2/137 (1%)
 Frame = +1

Query: 172 QSLCGCHFCQICIKNYQNSGSKNCPGNTDECKSENLTNIFPDRGTNK-RISNLIARCPHE 348
           ++ CG    +  +  +  S    CP  T  C       +F    +++ +   L   CP++
Sbjct: 168 ENKCGARMMRRLLAQHATS---ECPKRTQPCTYCTKEFVFDTIQSHQYQCPRLPVACPNQ 224

Query: 349 SCSHECRLIEMEDHMR-FCSTRNVNCPFNNVGCEHEEMNIDKLDDHMLLEIVNHNKILID 525
                    ++  H++  C+T  V CPF + GC+H    +  +  H+   +  H  ++  
Sbjct: 225 CGVGTVAREDLPGHLKDSCNTALVLCPFKDSGCKHRCPKL-AMARHVEESVKPHLAMMCA 283

Query: 526 IIGNLRSDVRELKEKEE 576
           ++   R +++EL+ + E
Sbjct: 284 LVSRQRQELQELRRELE 300
>sp|Q91187|RAG1_ONCMY V(D)J recombination-activating protein 1 (RAG-1)
          Length = 1073

 Score = 45.4 bits (106), Expect = 2e-04
 Identities = 28/85 (32%), Positives = 37/85 (43%)
 Frame = +1

Query: 136 CVIWKEILVNAQQSLCGCHFCQICIKNYQNSGSKNCPGNTDECKSENLTNIFPDRGTNKR 315
           C +   +L    QS C   FC+ CI  Y  S   +CP  T  C   +LT   P +G    
Sbjct: 310 CQVCDHLLSEPVQSPCRHLFCRSCIAKYIYSLGPHCPACTLPCGPADLT--APAKGFLGV 367

Query: 316 ISNLIARCPHESCSHECRLIEMEDH 390
           + +L   CP ESC  + RL     H
Sbjct: 368 LHSLPLLCpreSCGEQVRLDSFRAH 392
>sp|Q61382|TRAF4_MOUSE TNF receptor-associated factor 4 (Cysteine-rich motif associated to
           RING and Traf domains protein 1)
          Length = 470

 Score = 44.7 bits (104), Expect = 3e-04
 Identities = 24/90 (26%), Positives = 40/90 (44%), Gaps = 2/90 (2%)
 Frame = +1

Query: 163 NAQQSLCGCHFCQICIKNYQNSGSKNCPGNTDECKSENLTNIFPDRGTNKRISNLIARCP 342
           + + S CG  +C  C++ + + G   CP   ++    +   I+PD     ++  L  RC 
Sbjct: 28  SVEVSTCGHRYCDNCLQEFLSEGVFKCP---EDQLPLDYAKIYPDPELEVQVLGLAIRCI 84

Query: 343 H--ESCSHECRLIEMEDHMRFCSTRNVNCP 426
           H  E C     L  ++ H+  CS   V CP
Sbjct: 85  HSEEGCRWSGPLRHLQGHLNTCSFNVVPCP 114

 Score = 34.3 bits (77), Expect = 0.39
 Identities = 26/137 (18%), Positives = 57/137 (41%), Gaps = 2/137 (1%)
 Frame = +1

Query: 172 QSLCGCHFCQICIKNYQNSGSKNCPGNTDECKSENLTNIFPDRGTNK-RISNLIARCPHE 348
           ++ CG    +  +  +  S    CP  T  C       ++    +++ +   L   CP++
Sbjct: 168 ENKCGARMMRRLLAQHATS---ECPKRTQPCAYCTKEFVYDTIQSHQYQCPRLPVPCPNQ 224

Query: 349 SCSHECRLIEMEDHMR-FCSTRNVNCPFNNVGCEHEEMNIDKLDDHMLLEIVNHNKILID 525
                    ++  H++  C T  V CPF   GC+H    +  +  H+   +  H  ++  
Sbjct: 225 CGVGTVAREDLPTHLKDSCRTAFVLCPFKESGCKHRCPKL-AMGRHVEESVKPHLAMMCA 283

Query: 526 IIGNLRSDVRELKEKEE 576
           ++   R +++EL+ + E
Sbjct: 284 LVSRQRQELQELRRELE 300
>sp|O13033|RAG1_BRARE V(D)J recombination-activating protein 1 (RAG-1)
          Length = 1057

 Score = 43.5 bits (101), Expect = 6e-04
 Identities = 26/85 (30%), Positives = 38/85 (44%)
 Frame = +1

Query: 136 CVIWKEILVNAQQSLCGCHFCQICIKNYQNSGSKNCPGNTDECKSENLTNIFPDRGTNKR 315
           C +   +L +  QS C   FC++CI  Y ++   NCP         +L  I P +     
Sbjct: 296 CQVCDHLLSDPVQSPCRHLFCRLCIIRYTHALGPNCPTCNQHLNPSHL--IKPAKFFLAT 353

Query: 316 ISNLIARCPHESCSHECRLIEMEDH 390
           +S+L   CP E CS   RL    +H
Sbjct: 354 LSSLPLLCPSEECSDWVRLDSFREH 378
  Database: Non-redundant SwissProt sequences
    Posted date:  Dec 6, 2005  7:40 AM
  Number of letters in database: 68,354,980
  Number of sequences in database:  184,735
  
  Database: swissprot.01
    Posted date:  Dec 6, 2005  8:18 AM
  Number of letters in database: 66,202,850
  Number of sequences in database:  184,431
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 71,321,126
Number of Sequences: 369166
Number of extensions: 1350339
Number of successful extensions: 3974
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 3805
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3961
length of database: 68,354,980
effective HSP length: 108
effective length of database: 48,403,600
effective search space used: 7260540000
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)