Planaria EST Database


DrC_01514

BLASTX 2.2.13 [Nov-27-2005]

Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= DrC_01514
         (813 letters)

Database: Non-redundant SwissProt sequences 
           184,735 sequences; 68,354,980 total letters



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

sp|Q8VCM8|NCLN_MOUSE  Nicalin precursor (Nicastrin-like prot...   171   3e-42
sp|Q5XIA1|NCLN_RAT  Nicalin precursor (Nicastrin-like protein)    169   8e-42
sp|Q969V3|NCLN_HUMAN  Nicalin precursor (Nicastrin-like prot...   169   1e-41
sp|Q6NZ07|NCLN_BRARE  Nicalin-1 precursor (Nicastrin-like pr...   165   2e-40
sp|Q5ZJH2|NCLN_CHICK  Nicalin precursor (Nicastrin-like prot...   143   5e-34
sp|O31501|SWRC_BACSU  Swarming motility protein swrC               35   0.32 
sp|Q5MZM0|Y2310_SYNP6  Hypothetical UPF0182 protein syc2310_c      34   0.54 
sp|Q68XE8|SYT_RICTY  Threonyl-tRNA synthetase (Threonine--tR...    32   2.1  
sp|P22003|BMP5_HUMAN  Bone morphogenetic protein 5 precursor...    31   4.6  
sp|P54675|PI3K3_DICDI  Phosphatidylinositol 3-kinase 3 (PI3-...    31   4.6  
>sp|Q8VCM8|NCLN_MOUSE Nicalin precursor (Nicastrin-like protein)
          Length = 563

 Score =  171 bits (432), Expect = 3e-42
 Identities = 96/239 (40%), Positives = 144/239 (60%), Gaps = 10/239 (4%)
 Frame = +2

Query: 44   LFVHVSKPPKEGTSGHRLVEALNYTAT--LFNSSVNIVHKRINLNDDELQWEHERFSLRK 217
            L +HVSKPP+EGT  H  +  L   A     + S ++VHK+INL DD L WEHERF++R+
Sbjct: 320  LRLHVSKPpreGTLQHAFLRELETVAAHQFPDVSFSMVHKKINLADDVLAWEHERFAIRR 379

Query: 218  IPAITIS-AEKDRLNNRKSILD--DRISVELLQRNTLSVADSLMRLLYGLEDGHGP---- 376
            +PA T+S  E  R   R SI+D   R+  + L RNT  +A++L R++Y L +   P    
Sbjct: 380  LPAFTLSHLESHRAGPRSSIMDVRSRVDSKTLTRNTRIIAEALTRVIYNLTEKGTPPDMP 439

Query: 377  -ITEDHWVSEEAINADLALLTRFPRGQQLIDPKHPLVLSWERMFNRYLQNVRTTKIRADP 553
              TE   V EE I++ +  LT  PR  QL+D     + + E   +RYL++VR   ++AD 
Sbjct: 440  VFTEQMQVQEEQIDSVMDWLTNQPRAAQLLDKDGTFLSTLEHFLSRYLKDVRQHHVKADK 499

Query: 554  RDPEFVLYSDAEVIVTAHRVKPALFDFMVACVIISYLGLVYLFIENFSSISRFVLKISL 730
            RDPEFV Y   + ++ A+RVKPA+FD ++A  I +YLG+ Y  +++F  + + V ++ L
Sbjct: 500  RDPEFVFYDQLKQVMNAYRVKPAIFDLLLALCIGAYLGMAYTAVQHFHVLYKTVQRLLL 558
>sp|Q5XIA1|NCLN_RAT Nicalin precursor (Nicastrin-like protein)
          Length = 563

 Score =  169 bits (428), Expect = 8e-42
 Identities = 95/239 (39%), Positives = 144/239 (60%), Gaps = 10/239 (4%)
 Frame = +2

Query: 44   LFVHVSKPPKEGTSGHRLVEALNYTAT--LFNSSVNIVHKRINLNDDELQWEHERFSLRK 217
            L +HVSKPP+EGT  H  +  L   A     + S ++VHK+INL DD L WEHERF++R+
Sbjct: 320  LRLHVSKPpreGTLQHVFLRELEMVAAHQFPDVSFSMVHKKINLADDVLAWEHERFAIRR 379

Query: 218  IPAITIS-AEKDRLNNRKSILD--DRISVELLQRNTLSVADSLMRLLYGLEDGHGP---- 376
            +PA T+S  E  R   R SI+D   R+  + L RNT  +A++L R++Y L +   P    
Sbjct: 380  LPAFTLSHLENHRAGPRSSIMDVRSRVDSKTLTRNTRIIAEALTRVIYNLTEKGTPPDMP 439

Query: 377  -ITEDHWVSEEAINADLALLTRFPRGQQLIDPKHPLVLSWERMFNRYLQNVRTTKIRADP 553
              TE   V +E I++ +  LT  PR  QL+D     + + E   +RYL++VR   ++AD 
Sbjct: 440  VFTEQMQVQQEQIDSVMDWLTNQPRAAQLLDKDGTFLSTLEHFLSRYLKDVRQHHVKADK 499

Query: 554  RDPEFVLYSDAEVIVTAHRVKPALFDFMVACVIISYLGLVYLFIENFSSISRFVLKISL 730
            RDPEFV Y   + ++ A+RVKPA+FD ++A  I +YLG+ Y  +++F  + + V ++ L
Sbjct: 500  RDPEFVFYDQLKQVMNAYRVKPAIFDLLLALCIGAYLGMAYTAVQHFHVLYKTVQRLLL 558
>sp|Q969V3|NCLN_HUMAN Nicalin precursor (Nicastrin-like protein)
          Length = 563

 Score =  169 bits (427), Expect = 1e-41
 Identities = 97/255 (38%), Positives = 153/255 (60%), Gaps = 10/255 (3%)
 Frame = +2

Query: 8    VCLERLALSDGGLFVHVSKPPKEGTSGHRLVEALNYTATLFNSSV--NIVHKRINLNDDE 181
            +CL+ +      L +HVSKPP+EGT  H  +  L   A      V  ++VHKRINL +D 
Sbjct: 309  LCLDTVGRGSS-LHLHVSKPpreGTLQHAFLRELETVAAHQFPEVRFSMVHKRINLAEDV 367

Query: 182  LQWEHERFSLRKIPAITIS-AEKDRLNNRKSILD--DRISVELLQRNTLSVADSLMRLLY 352
            L WEHERF++R++PA T+S  E  R   R SI+D   R+  + L RNT  +A++L R++Y
Sbjct: 368  LAWEHERFAIRRLPAFTLSHLESHRDGQRSSIMDVRSRVDSKTLTRNTRIIAEALTRVIY 427

Query: 353  GLEDGHGP-----ITEDHWVSEEAINADLALLTRFPRGQQLIDPKHPLVLSWERMFNRYL 517
             L +   P      TE   + +E +++ +  LT  PR  QL+D     + + E   +RYL
Sbjct: 428  NLTEKGTPPDMPVFTEQMQIQQEQLDSVMDWLTNQPRAAQLVDKDSTFLSTLEHHLSRYL 487

Query: 518  QNVRTTKIRADPRDPEFVLYSDAEVIVTAHRVKPALFDFMVACVIISYLGLVYLFIENFS 697
            ++V+   ++AD RDPEFV Y   + ++ A+RVKPA+FD ++A  I +YLG+ Y+ +++FS
Sbjct: 488  KDVKQHHVKADKRDPEFVFYDQLKQVMNAYRVKPAVFDLLLAVGIAAYLGMAYVAVQHFS 547

Query: 698  SISRFVLKISLVQEK 742
             + + V ++ LV+ K
Sbjct: 548  LLYKTVQRL-LVKAK 561
>sp|Q6NZ07|NCLN_BRARE Nicalin-1 precursor (Nicastrin-like protein 1)
          Length = 572

 Score =  165 bits (417), Expect = 2e-40
 Identities = 102/270 (37%), Positives = 154/270 (57%), Gaps = 25/270 (9%)
 Frame = +2

Query: 8    VCLERLALSDGGLFVHVSKPPKEGTSGHRLVEALNYTATLFNSSVN--IVHKRINLNDDE 181
            +CL+ L  SD  L +HVSKPPKEG+  + L++ L       +  +   +VHK+INL DD 
Sbjct: 302  LCLDTLGNSDN-LHLHVSKPPKEGSPQYTLLKELETVVAHQHPDLKFAMVHKKINLADDT 360

Query: 182  LQWEHERFSLRKIPAITIS-AEKDRLNNRKSILDDR-----------------ISVELLQ 307
            L WEHERF +R++PA T+S  E  R   R SI+D R                 + +  L 
Sbjct: 361  LAWEHERFGIRRLPAFTLSHLESHRSPARHSIMDMRSVSPSLEGAGEATTGPHVDLGKLS 420

Query: 308  RNTLSVADSLMRLLYGLED----GHGPI-TEDHWVSEEAINADLALLTRFPRGQQLIDPK 472
            RNT  +A++L R++Y L +    G   I TE   V E+ + + +  LT  PR  QL+D  
Sbjct: 421  RNTKVIAETLARVIYNLTEKGVTGDLEIFTEQMQVQEDQLASLVDWLTAQPRAAQLLDKD 480

Query: 473  HPLVLSWERMFNRYLQNVRTTKIRADPRDPEFVLYSDAEVIVTAHRVKPALFDFMVACVI 652
              ++ + E   +RYL++V+   +RAD RDPEFV Y   +  + A+RVKPA+FD ++A  I
Sbjct: 481  SSIINTLEHQLSRYLKDVKRHLVRADKRDPEFVFYDQLKQTMNAYRVKPAIFDLLLAVCI 540

Query: 653  ISYLGLVYLFIENFSSISRFVLKISLVQEK 742
             SYLG++YL I+NF  +  F+ +++  + K
Sbjct: 541  ASYLGVLYLAIQNFGLLYGFLRRVTAPRVK 570
>sp|Q5ZJH2|NCLN_CHICK Nicalin precursor (Nicastrin-like protein)
          Length = 562

 Score =  143 bits (361), Expect = 5e-34
 Identities = 90/259 (34%), Positives = 138/259 (53%), Gaps = 18/259 (6%)
 Frame = +2

Query: 8    VCLERLALSDGGLFVHVSKPPKEGTSGHRLVEALNYTATLFNSSV--NIVHKRINLNDDE 181
            +CL+ L   +  L +HVSKPPKEGT  H  +  L          V  ++VHK+INL +D 
Sbjct: 308  LCLDTLGRGNS-LHLHVSKPPKEGTLQHAFLRELEMVVASQFPEVKFSMVHKKINLAEDI 366

Query: 182  LQWEHERFSLRKIPAITIS-AEKDRLNNRKSILDDRISVELLQRNTLSVADSLMRLLYGL 358
            L WEHERF++R++PA TIS  E  R + R SI+D R  V+     T ++         G 
Sbjct: 367  LAWEHERFAIRRLPAFTISHLESHRDSLRNSIMDRRSQVD-----TKALTQEYQDHCGGF 421

Query: 359  EDGHGPITEDHWVSEEAINADL---------------ALLTRFPRGQQLIDPKHPLVLSW 493
            ++GH    + +       +ADL                L  +  +  QLID     + + 
Sbjct: 422  DEGH---LQPNREGSTCRSADLHGSDADPGGAARISDGLAEQSAQAAQLIDKDSTFLSTL 478

Query: 494  ERMFNRYLQNVRTTKIRADPRDPEFVLYSDAEVIVTAHRVKPALFDFMVACVIISYLGLV 673
            E    RYL++V+   ++AD RDPEFV Y   + ++ A+RVKPA+FD ++A  I +YLG+ 
Sbjct: 479  EYYMGRYLKDVKQHHVKADKRDPEFVFYDQLKQVMNAYRVKPAIFDLLLAVCIAAYLGVA 538

Query: 674  YLFIENFSSISRFVLKISL 730
            Y+ ++NF  + R + ++SL
Sbjct: 539  YVAVQNFGLLYRMIQRLSL 557
>sp|O31501|SWRC_BACSU Swarming motility protein swrC
          Length = 1052

 Score = 34.7 bits (78), Expect = 0.32
 Identities = 23/69 (33%), Positives = 31/69 (44%)
 Frame = +2

Query: 155 KRINLNDDELQWEHERFSLRKIPAITISAEKDRLNNRKSILDDRISVELLQRNTLSVADS 334
           + +NL DD    E  R+SL   P +T+S   D+ N              LQ  T  V DS
Sbjct: 114 ENVNLPDDAKDPEISRYSLNSFPILTLSVSSDKDN--------------LQELTKQVEDS 159

Query: 335 LMRLLYGLE 361
           L+  L G+E
Sbjct: 160 LVSKLEGIE 168
>sp|Q5MZM0|Y2310_SYNP6 Hypothetical UPF0182 protein syc2310_c
          Length = 955

 Score = 33.9 bits (76), Expect = 0.54
 Identities = 16/59 (27%), Positives = 31/59 (52%), Gaps = 2/59 (3%)
 Frame = +2

Query: 458 LIDPKHPLVLSWERMFNRYLQ--NVRTTKIRADPRDPEFVLYSDAEVIVTAHRVKPALF 628
           ++DPK PL+ +W R+F    Q  +     +R+  R P  +  + +  ++T H + P +F
Sbjct: 703 IVDPKDPLIQTWSRLFPSLFQPIDAMAPVLRSHLRYPTDLFKAQSSQLLTYHVLDPQVF 761
>sp|Q68XE8|SYT_RICTY Threonyl-tRNA synthetase (Threonine--tRNA ligase) (ThrRS)
          Length = 635

 Score = 32.0 bits (71), Expect = 2.1
 Identities = 17/57 (29%), Positives = 32/57 (56%)
 Frame = +2

Query: 104 ALNYTATLFNSSVNIVHKRINLNDDELQWEHERFSLRKIPAITISAEKDRLNNRKSI 274
           AL    TL +   N +   IN++ D++ ++   FS +KIP I +  +K++ N + +I
Sbjct: 554 ALEVQKTLID---NNIRTDINISPDKINYKIREFSNQKIPMIAVIGKKEQANKQVTI 607
>sp|P22003|BMP5_HUMAN Bone morphogenetic protein 5 precursor (BMP-5)
          Length = 454

 Score = 30.8 bits (68), Expect = 4.6
 Identities = 33/128 (25%), Positives = 53/128 (41%), Gaps = 14/128 (10%)
 Frame = +2

Query: 119 ATLFNSSVNIVHKRINLNDDELQWEHERFSLRKIP------AITISAEKDRLNNRKSILD 280
           A +  S VN+V +  + +     ++  RF L +IP      A      KDR NNR     
Sbjct: 154 ADMVMSFVNLVERDKDFSHQRRHYKEFRFDLTQIPHGEAVTAAEFRIYKDRSNNRFENET 213

Query: 281 DRISV-ELLQRNTLSVADSLM---RLLYGLEDG----HGPITEDHWVSEEAINADLALLT 436
            +IS+ ++++  T   AD  +   R    L+ G       +T +HWV     N  L L  
Sbjct: 214 IKISIYQIIKEYTNRDADLFLLDTRKAQALDVGWLVFDITVTSNHWVINPQNNLGLQLCA 273

Query: 437 RFPRGQQL 460
               G+ +
Sbjct: 274 ETGDGRSI 281
>sp|P54675|PI3K3_DICDI Phosphatidylinositol 3-kinase 3 (PI3-kinase) (PtdIns-3-kinase)
           (PI3K)
          Length = 1585

 Score = 30.8 bits (68), Expect = 4.6
 Identities = 25/95 (26%), Positives = 44/95 (46%), Gaps = 7/95 (7%)
 Frame = +2

Query: 131 NSSVNIVHKRINLNDDELQWEHERFSLRKIPAITISAEKDRLNN--RKSILDDRISVELL 304
           N+   I +   N ND+  + E    SL+++       EK++L N  R+ IL +R  ++ L
Sbjct: 377 NNEELINNNNNNNNDENYKIEETEESLKEL------LEKEKLENEEREKILKERNEIDNL 430

Query: 305 QRNTLSVADSLMRLLY-----GLEDGHGPITEDHW 394
           ++         MR        GLE+   P+ ++HW
Sbjct: 431 KKKNHLSKGYFMRACNASNDDGLEEEDIPLQDEHW 465
  Database: Non-redundant SwissProt sequences
    Posted date:  Dec 6, 2005  7:40 AM
  Number of letters in database: 68,354,980
  Number of sequences in database:  184,735
  
  Database: swissprot.01
    Posted date:  Dec 6, 2005  8:18 AM
  Number of letters in database: 66,202,850
  Number of sequences in database:  184,431
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 94,553,804
Number of Sequences: 369166
Number of extensions: 1953388
Number of successful extensions: 4837
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 4697
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4825
length of database: 68,354,980
effective HSP length: 109
effective length of database: 48,218,865
effective search space used: 7763237265
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)