Planaria EST Database


DrC_01493

BLASTX 2.2.13 [Nov-27-2005]

Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= DrC_01493
         (752 letters)

Database: Non-redundant SwissProt sequences 
           184,735 sequences; 68,354,980 total letters



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

sp|Q13614|MTMR2_HUMAN  Myotubularin-related protein 2             259   7e-69
sp|Q9Z2D1|MTMR2_MOUSE  Myotubularin-related protein 2             258   1e-68
sp|Q9Z2C4|MTMR1_MOUSE  Myotubularin-related protein 1             245   8e-65
sp|Q9Z2C5|MTM1_MOUSE  Myotubularin                                244   1e-64
sp|Q13496|MTM1_HUMAN  Myotubularin                                244   2e-64
sp|Q13613|MTMR1_HUMAN  Myotubularin-related protein 1             243   3e-64
sp|Q9Z2C9|MTMR7_MOUSE  Myotubularin-related protein 7             197   2e-50
sp|Q9Y217|MTMR6_HUMAN  Myotubularin-related protein 6             194   2e-49
sp|Q22712|YW91_CAEEL  Hypothetical protein T24A11.1 in chrom...   176   6e-44
sp|Q9Y216|MTMR7_HUMAN  Myotubularin-related protein 7             169   6e-42
>sp|Q13614|MTMR2_HUMAN Myotubularin-related protein 2
          Length = 643

 Score =  259 bits (661), Expect = 7e-69
 Identities = 120/230 (52%), Positives = 169/230 (73%), Gaps = 1/230 (0%)
 Frame = +1

Query: 1   FQRQLIESNNWRISKVNHNYEVCETYPDEVAVPKDVSDETITNACQFRTKNRFPVLCWIH 180
           ++RQ I + +WRI+K+N  YE+C+TYP  + VP ++ DE +     FR++ R PVL WIH
Sbjct: 215 YRRQGIPNESWRITKINERYELCDTYPALLVVPANIPDEELKRVASFRSRGRIPVLSWIH 274

Query: 181 PDTKATLTRSSQPATGLTWKRNESDERYLKAIKDANAYNNLLTIIDARPMINARANMARG 360
           P+++AT+TR SQP  G++ KR++ DE+YL+AI D+NA ++ + I DARP +NA AN A+G
Sbjct: 275 PESQATITRCSQPMVGVSGKRSKEDEKYLQAIMDSNAQSHKIFIFDARPSVNAVANKAKG 334

Query: 361 GGIESQNIYTSISYDFLNIPNIHVMRESMRKLADLCYPKPDNNNWNKALEETKWLNYIRQ 540
           GG ES++ Y +    FL+I NIHVMRES+RKL ++ YP  +  +W   LE T WL +I+ 
Sbjct: 335 GGYESEDAYQNAELVFLDIHNIHVMRESLRKLKEIVYPNIEETHWLSNLESTHWLEHIKL 394

Query: 541 ILLGSLMVAEKINS-QRSVLVHCSDGWDRTAQITSLPQLMLDPYFRTIRG 687
           IL G+L +A+K+ S + SV+VHCSDGWDRTAQ+TSL  LMLD Y+RTIRG
Sbjct: 395 ILAGALRIADKVESGKTSVVVHCSDGWDRTAQLTSLAMLMLDGYYRTIRG 444
>sp|Q9Z2D1|MTMR2_MOUSE Myotubularin-related protein 2
          Length = 643

 Score =  258 bits (659), Expect = 1e-68
 Identities = 120/230 (52%), Positives = 169/230 (73%), Gaps = 1/230 (0%)
 Frame = +1

Query: 1   FQRQLIESNNWRISKVNHNYEVCETYPDEVAVPKDVSDETITNACQFRTKNRFPVLCWIH 180
           ++RQ I + +WRI+K+N  YE+C+TYP  + VP ++ DE +     FR++ R PVL WIH
Sbjct: 215 YRRQGIPNESWRITKINERYELCDTYPALLVVPANIPDEELKRVASFRSRGRIPVLSWIH 274

Query: 181 PDTKATLTRSSQPATGLTWKRNESDERYLKAIKDANAYNNLLTIIDARPMINARANMARG 360
           P+++AT+TR SQP  G++ KR++ DE+YL+AI D+NA ++ + I DARP +NA AN A+G
Sbjct: 275 PESQATVTRCSQPMVGVSGKRSKEDEKYLQAIMDSNAQSHKIFIFDARPSVNAVANKAKG 334

Query: 361 GGIESQNIYTSISYDFLNIPNIHVMRESMRKLADLCYPKPDNNNWNKALEETKWLNYIRQ 540
           GG ES++ Y +    FL+I NIHVMRES+RKL ++ YP  +  +W   LE T WL +I+ 
Sbjct: 335 GGYESEDAYQNAELVFLDIHNIHVMRESLRKLKEIVYPTIEETHWLSNLESTHWLEHIKL 394

Query: 541 ILLGSLMVAEKINS-QRSVLVHCSDGWDRTAQITSLPQLMLDPYFRTIRG 687
           IL G+L +A+K+ S + SV+VHCSDGWDRTAQ+TSL  LMLD Y+RTIRG
Sbjct: 395 ILAGALRIADKVESGKTSVVVHCSDGWDRTAQLTSLAMLMLDGYYRTIRG 444
>sp|Q9Z2C4|MTMR1_MOUSE Myotubularin-related protein 1
          Length = 669

 Score =  245 bits (626), Expect = 8e-65
 Identities = 116/230 (50%), Positives = 161/230 (70%), Gaps = 1/230 (0%)
 Frame = +1

Query: 1   FQRQLIESNNWRISKVNHNYEVCETYPDEVAVPKDVSDETITNACQFRTKNRFPVLCWIH 180
           ++RQ + + +W+ISK+N NYE C+TYP  + VP  V D+ ++    FR K R PVL WIH
Sbjct: 240 YKRQGLPNESWKISKINSNYEFCDTYPAIIVVPTSVKDDDLSKVAAFRAKGRVPVLSWIH 299

Query: 181 PDTKATLTRSSQPATGLTWKRNESDERYLKAIKDANAYNNLLTIIDARPMINARANMARG 360
           P+++AT+TR SQP  G   KR + DE+YL+ I DANA ++ LTI DAR    A  N A+G
Sbjct: 300 PESQATITRCSQPLVGPNDKRCKEDEKYLQTIMDANAQSHKLTIFDARQNSVADTNKAKG 359

Query: 361 GGIESQNIYTSISYDFLNIPNIHVMRESMRKLADLCYPKPDNNNWNKALEETKWLNYIRQ 540
           GG E+++ Y +    FL I NIHVMRES+RKL ++ YP  D ++W   ++ T WL YIR 
Sbjct: 360 GGYENESAYPNAELIFLEIHNIHVMRESLRKLKEIVYPSIDESHWLSNVDGTHWLEYIRV 419

Query: 541 ILLGSLMVAEKINS-QRSVLVHCSDGWDRTAQITSLPQLMLDPYFRTIRG 687
           +L G++ +A+KI S + SV++HCSDGWDRT+Q+TSL  LMLD Y+RTI+G
Sbjct: 420 LLAGAVRIADKIESGKTSVVIHCSDGWDRTSQLTSLAMLMLDSYYRTIKG 469
>sp|Q9Z2C5|MTM1_MOUSE Myotubularin
          Length = 603

 Score =  244 bits (624), Expect = 1e-64
 Identities = 114/230 (49%), Positives = 161/230 (70%), Gaps = 1/230 (0%)
 Frame = +1

Query: 1   FQRQLIESNNWRISKVNHNYEVCETYPDEVAVPKDVSDETITNACQFRTKNRFPVLCWIH 180
           ++RQ + +++WRIS +N  YE+CETYP  + VP   SD+ +     FR++NR PVL WIH
Sbjct: 173 YRRQGLPNHHWRISFINKCYELCETYPALLVVPYRTSDDDLRRIATFRSRNRLPVLSWIH 232

Query: 181 PDTKATLTRSSQPATGLTWKRNESDERYLKAIKDANAYNNLLTIIDARPMINARANMARG 360
           P+ K  + R SQP  G++ KRN+ DE+YL  I++ N   + L I DARP +NA AN A G
Sbjct: 233 PENKMVIMRCSQPLVGMSGKRNKDDEKYLDVIRETNKQTSKLMIYDARPSVNAVANKATG 292

Query: 361 GGIESQNIYTSISYDFLNIPNIHVMRESMRKLADLCYPKPDNNNWNKALEETKWLNYIRQ 540
           GG ES + Y +    FL+I NIHVMRES++K+ D+ YP  + ++W  +LE T WL +I+ 
Sbjct: 293 GGYESDDAYQNSELSFLDIHNIHVMRESLKKVKDIVYPNIEESHWLSSLESTHWLEHIKL 352

Query: 541 ILLGSLMVAEKINS-QRSVLVHCSDGWDRTAQITSLPQLMLDPYFRTIRG 687
           +L G++ VA++++S + SVLVHCSDGWDRTAQ+TSL  LMLD ++RTI G
Sbjct: 353 VLTGAIQVADQVSSGKSSVLVHCSDGWDRTAQLTSLAMLMLDSFYRTIEG 402
>sp|Q13496|MTM1_HUMAN Myotubularin
          Length = 603

 Score =  244 bits (622), Expect = 2e-64
 Identities = 113/230 (49%), Positives = 162/230 (70%), Gaps = 1/230 (0%)
 Frame = +1

Query: 1   FQRQLIESNNWRISKVNHNYEVCETYPDEVAVPKDVSDETITNACQFRTKNRFPVLCWIH 180
           ++RQ + +++WRI+ +N  YE+C+TYP  + VP   SD+ +     FR++NR PVL WIH
Sbjct: 173 YRRQGLPNHHWRITFINKCYELCDTYPALLVVPYRASDDDLRRVATFRSRNRIPVLSWIH 232

Query: 181 PDTKATLTRSSQPATGLTWKRNESDERYLKAIKDANAYNNLLTIIDARPMINARANMARG 360
           P+ K  + R SQP  G++ KRN+ DE+YL  I++ N   + LTI DARP +NA AN A G
Sbjct: 233 PENKTVIVRCSQPLVGMSGKRNKDDEKYLDVIRETNKQISKLTIYDARPSVNAVANKATG 292

Query: 361 GGIESQNIYTSISYDFLNIPNIHVMRESMRKLADLCYPKPDNNNWNKALEETKWLNYIRQ 540
           GG ES + Y +    FL+I NIHVMRES++K+ D+ YP  + ++W  +LE T WL +I+ 
Sbjct: 293 GGYESDDAYHNAELFFLDIHNIHVMRESLKKVKDIVYPNVEESHWLSSLESTHWLEHIKL 352

Query: 541 ILLGSLMVAEKINS-QRSVLVHCSDGWDRTAQITSLPQLMLDPYFRTIRG 687
           +L G++ VA+K++S + SVLVHCSDGWDRTAQ+TSL  LMLD ++R+I G
Sbjct: 353 VLTGAIQVADKVSSGKSSVLVHCSDGWDRTAQLTSLAMLMLDSFYRSIEG 402
>sp|Q13613|MTMR1_HUMAN Myotubularin-related protein 1
          Length = 665

 Score =  243 bits (621), Expect = 3e-64
 Identities = 117/230 (50%), Positives = 157/230 (68%), Gaps = 1/230 (0%)
 Frame = +1

Query: 1   FQRQLIESNNWRISKVNHNYEVCETYPDEVAVPKDVSDETITNACQFRTKNRFPVLCWIH 180
           ++RQ + + +W+ISK+N NYE C+TYP  + VP  V D+ ++    FR K R PVL WIH
Sbjct: 236 YKRQGLPNESWKISKINSNYEFCDTYPAIIVVPTSVKDDDLSKVAAFRAKGRVPVLSWIH 295

Query: 181 PDTKATLTRSSQPATGLTWKRNESDERYLKAIKDANAYNNLLTIIDARPMINARANMARG 360
           P+++AT+TR SQP  G   KR + DE+YL+ I DANA ++ L I DAR    A  N  +G
Sbjct: 296 PESQATITRCSQPLVGPNDKRCKEDEKYLQTIMDANAQSHKLIIFDARQNSVADTNKTKG 355

Query: 361 GGIESQNIYTSISYDFLNIPNIHVMRESMRKLADLCYPKPDNNNWNKALEETKWLNYIRQ 540
           GG ES++ Y +    FL I NIHVMRES+RKL ++ YP  D   W   ++ T WL YIR 
Sbjct: 356 GGYESESAYPNAELVFLEIHNIHVMRESLRKLKEIVYPSIDEARWLSNVDGTHWLEYIRM 415

Query: 541 ILLGSLMVAEKINS-QRSVLVHCSDGWDRTAQITSLPQLMLDPYFRTIRG 687
           +L G++ +A+KI S + SV+VHCSDGWDRTAQ+TSL  LMLD Y+RTI+G
Sbjct: 416 LLAGAVRIADKIESGKTSVVVHCSDGWDRTAQLTSLAMLMLDSYYRTIKG 465
>sp|Q9Z2C9|MTMR7_MOUSE Myotubularin-related protein 7
          Length = 660

 Score =  197 bits (502), Expect = 2e-50
 Identities = 94/231 (40%), Positives = 156/231 (67%), Gaps = 2/231 (0%)
 Frame = +1

Query: 1   FQRQLIESNNWRISKVNHNYEVCETYPDEVAVPKDVSDETITNACQFRTKNRFPVLCWIH 180
           ++R  +  N W++S VN +Y VC++YP E+ VP+  +   I  + +FR++ RFP L +  
Sbjct: 136 YKRMGLPDNYWQLSDVNRDYRVCDSYPTELYVPRSATAHIIVGSSKFRSRRRFPALSYYC 195

Query: 181 PDTKATLTRSSQPATGLTWKRNESDERYLKAIKDANAYNNLLTIIDARPMINARANMARG 360
            D+ A++ RSSQP +G + +  E DE+ L+AI+ AN  ++ + ++D RP +NA AN A G
Sbjct: 196 KDSHASICRSSQPLSGFSARCLE-DEQMLQAIRKANPGSDFIYVVDTRPKLNAMANRAAG 254

Query: 361 GGIESQNIYTSISYDFLNIPNIHVMRESMRKLADLCYPK-PDNNNWNKALEETKWLNYIR 537
            G E+++ Y++I + F+ I NIHVMR S++K+ ++C  K P  +++   LE + WL +I+
Sbjct: 255 KGYENEDNYSNIKFQFIGIENIHVMRNSLQKMLEVCELKSPSMSDFLWGLENSGWLRHIK 314

Query: 538 QILLGSLMVAEKINSQ-RSVLVHCSDGWDRTAQITSLPQLMLDPYFRTIRG 687
            I+   + +A+ ++ +  SVLVHCSDGWDRTAQ+ S+  L+LDPY+RT++G
Sbjct: 315 AIMDAGIFIAKAVSEEGASVLVHCSDGWDRTAQVCSVASLLLDPYYRTLKG 365
>sp|Q9Y217|MTMR6_HUMAN Myotubularin-related protein 6
          Length = 621

 Score =  194 bits (493), Expect = 2e-49
 Identities = 97/231 (41%), Positives = 151/231 (65%), Gaps = 2/231 (0%)
 Frame = +1

Query: 1   FQRQLIESNNWRISKVNHNYEVCETYPDEVAVPKDVSDETITNACQFRTKNRFPVLCWIH 180
           ++R  + +++W++S  N +Y++CETYP E+ VP+  S   I  + +FR+K RFPVL + H
Sbjct: 134 YKRMGVPNSHWQLSDANRDYKICETYpreLYVPRIASKPIIVGSSKFRSKGRFPVLSYYH 193

Query: 181 PDTKATLTRSSQPATGLTWKRNESDERYLKAIKDANAYNNLLTIIDARPMINARANMARG 360
            D +A + R SQP +G +  R   DE  L+AI  AN  N  + ++D RP +NA AN A G
Sbjct: 194 QDKEAAICRCSQPLSGFS-ARCLEDEHLLQAISKANPVNRYMYVMDTRPKLNAMANRAAG 252

Query: 361 GGIESQNIYTSISYDFLNIPNIHVMRESMRKLADLCYPKP-DNNNWNKALEETKWLNYIR 537
            G E+++ Y++I + F+ I NIHVMR S++KL ++   K    N++   LE + WL +I+
Sbjct: 253 KGYENEDNYSNIRFQFVGIENIHVMRSSLQKLLEVNGTKGLSVNDFYSGLESSGWLRHIK 312

Query: 538 QILLGSLMVAEKINSQR-SVLVHCSDGWDRTAQITSLPQLMLDPYFRTIRG 687
            ++  ++ +A+ I  +  SVLVHCSDGWDRT+Q+ SL  L+LD Y+RTI+G
Sbjct: 313 AVMDAAVFLAKAITVENASVLVHCSDGWDRTSQVCSLGSLLLDSYYRTIKG 363
>sp|Q22712|YW91_CAEEL Hypothetical protein T24A11.1 in chromosome III
          Length = 938

 Score =  176 bits (446), Expect = 6e-44
 Identities = 88/226 (38%), Positives = 132/226 (58%), Gaps = 4/226 (1%)
 Frame = +1

Query: 22  SNNWRISKVNHNYEVCETYPDEVAVPKDVSDETITNACQFRTKNRFPVLCWIHPDTKATL 201
           S +++IS VN N+EVC TYP+++ VPK ++D+ I     +R+  RFP + W    T+A L
Sbjct: 261 SEHFQISSVNENFEVCPTYPEKIIVPKGITDDDIRKGAPYRSIGRFPAVIWRCRKTRAVL 320

Query: 202 TRSSQPATGLTWKRNESDERYL----KAIKDANAYNNLLTIIDARPMINARANMARGGGI 369
            RSSQP  G+   RN +DE+ +    KA +          I+DAR   +A AN AR GG 
Sbjct: 321 MRSSQPQVGILSWRNPTDEKIIEEAVKASRIEGEEKKQFIIMDARGYTSAFANRARSGGF 380

Query: 370 ESQNIYTSISYDFLNIPNIHVMRESMRKLADLCYPKPDNNNWNKALEETKWLNYIRQILL 549
           E+   Y     +FL +PNIH +R S   +  + +    N     +L+ T WL  +  +L+
Sbjct: 381 ENTEYYQQAKLEFLGLPNIHAVRGSFNNVRTMLHNLGPNEQLLTSLQTTGWLLNLSNLLV 440

Query: 550 GSLMVAEKINSQRSVLVHCSDGWDRTAQITSLPQLMLDPYFRTIRG 687
            +   A+ ++   SVLVHCSDGWDRT Q+T+L ++MLD Y+RT++G
Sbjct: 441 NAANCADHLSKGHSVLVHCSDGWDRTTQVTTLAKIMLDEYYRTVKG 486
>sp|Q9Y216|MTMR7_HUMAN Myotubularin-related protein 7
          Length = 391

 Score =  169 bits (429), Expect = 6e-42
 Identities = 83/200 (41%), Positives = 136/200 (68%), Gaps = 2/200 (1%)
 Frame = +1

Query: 94  VPKDVSDETITNACQFRTKNRFPVLCWIHPDTKATLTRSSQPATGLTWKRNESDERYLKA 273
           VPK  +   I  + +FR++ RFPVL + + D  A++ RSSQP +G + +  E DE+ L+A
Sbjct: 3   VPKSATAHIIVGSSKFRSRRRFPVLSYYYKDNHASICRSSQPLSGFSARCLE-DEQMLQA 61

Query: 274 IKDANAYNNLLTIIDARPMINARANMARGGGIESQNIYTSISYDFLNIPNIHVMRESMRK 453
           I+ AN  ++ + ++D RP +NA AN A G G E+++ Y++I + F+ I NIHVMR S++K
Sbjct: 62  IRKANPGSDFVYVVDTRPKLNAMANRAAGKGYENEDNYSNIKFQFIGIENIHVMRNSLQK 121

Query: 454 LADLCYPK-PDNNNWNKALEETKWLNYIRQILLGSLMVAEKINSQ-RSVLVHCSDGWDRT 627
           + ++C  K P  +++   LE + WL +I+ I+   + +A+ ++ +  SVLVHCSDGWDRT
Sbjct: 122 MLEVCELKSPSMSDFLWGLENSGWLRHIKAIMDAGIFIAKAVSEEGASVLVHCSDGWDRT 181

Query: 628 AQITSLPQLMLDPYFRTIRG 687
           AQ+ S+  L+LDP++RT++G
Sbjct: 182 AQVCSVASLLLDPHYRTLKG 201
  Database: Non-redundant SwissProt sequences
    Posted date:  Dec 6, 2005  7:40 AM
  Number of letters in database: 68,354,980
  Number of sequences in database:  184,735
  
  Database: swissprot.01
    Posted date:  Dec 6, 2005  8:18 AM
  Number of letters in database: 66,202,850
  Number of sequences in database:  184,431
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 81,945,446
Number of Sequences: 369166
Number of extensions: 1555339
Number of successful extensions: 3905
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 3785
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3875
length of database: 68,354,980
effective HSP length: 108
effective length of database: 48,403,600
effective search space used: 6873311200
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)