Planaria EST Database


DrC_01492

BLASTX 2.2.13 [Nov-27-2005]

Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= DrC_01492
         (885 letters)

Database: Non-redundant SwissProt sequences 
           184,735 sequences; 68,354,980 total letters



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

sp|Q16254|E2F4_HUMAN  Transcription factor E2F4 (E2F-4)           173   5e-43
sp|Q15329|E2F5_HUMAN  Transcription factor E2F5 (E2F-5)           171   3e-42
sp|Q61502|E2F5_MOUSE  Transcription factor E2F5 (E2F-5)           170   4e-42
sp|Q62814|E2F5_RAT  Transcription factor E2F5 (E2F-5)             168   2e-41
sp|O35261|E2F3_MOUSE  Transcription factor E2F3 (E2F-3)           107   3e-23
sp|O00716|E2F3_HUMAN  Transcription factor E2F3 (E2F-3)           107   6e-23
sp|P56931|E2F2_MOUSE  Transcription factor E2F2 (E2F-2)           103   8e-22
sp|Q14209|E2F2_HUMAN  Transcription factor E2F2 (E2F-2)           100   5e-21
sp|O54917|E2F6_MOUSE  Transcription factor E2F6 (E2F-6) (E2F...    98   3e-20
sp|O75461|E2F6_HUMAN  Transcription factor E2F6 (E2F-6)            96   1e-19
>sp|Q16254|E2F4_HUMAN Transcription factor E2F4 (E2F-4)
          Length = 413

 Score =  173 bits (439), Expect = 5e-43
 Identities = 92/188 (48%), Positives = 125/188 (66%)
 Frame = -2

Query: 884 DGSLDLKIAAEYLAVRQKRRIYDITNVLEGIGLIEKKTKNSIQWKGGSAATNSPDMQQRQ 705
           DG LDLK+AA+ LAVRQKRRIYDITNVLEGIGLIEKK+KNSIQWKG     N+ ++  + 
Sbjct: 38  DGVLDLKLAADTLAVRQKRRIYDITNVLEGIGLIEKKSKNSIQWKGVGPGCNTREIADKL 97

Query: 704 TQLKSEVEYLDNLINKVEEHKNKLKQSIANVTEDLDNQEYAYLTHTDLINMFENKTMLVI 525
            +LK+E+E L     ++++HK  ++QSI NVTED+ N   AY+TH D+   F   T+L I
Sbjct: 98  IELKAEIEELQQREQELDQHKVWVQQSIRNVTEDVQNSCLAYVTHEDICRCFAGDTLLAI 157

Query: 524 KAPQGTDVSVPLPEDPSASDAPRSLFSLKKSFQVHLKSHTTPISVLLVKQDELTSQPKLR 345
           +AP GT + VP+PE  +           +K +Q+HLKS + PI VLLV ++  +S P   
Sbjct: 158 RAPSGTSLEVPIPEGLNG----------QKKYQIHLKSVSGPIEVLLVNKEAWSSPPVAV 207

Query: 344 NVPFVDDI 321
            VP  +D+
Sbjct: 208 PVPPPEDL 215

 Score = 33.9 bits (76), Expect = 0.62
 Identities = 13/22 (59%), Positives = 17/22 (77%)
 Frame = -2

Query: 173 DGDYLLILDETEGACDMFDIGV 108
           D DY+  LDE+EG CD+FD+ V
Sbjct: 389 DHDYIYNLDESEGVCDLFDVPV 410
>sp|Q15329|E2F5_HUMAN Transcription factor E2F5 (E2F-5)
          Length = 346

 Score =  171 bits (432), Expect = 3e-42
 Identities = 92/197 (46%), Positives = 128/197 (64%)
 Frame = -2

Query: 884 DGSLDLKIAAEYLAVRQKRRIYDITNVLEGIGLIEKKTKNSIQWKGGSAATNSPDMQQRQ 705
           DG LDLK AA+ LAVRQKRRIYDITNVLEGI LIEKK+KNSIQWKG  A  N+ ++  R 
Sbjct: 71  DGVLDLKAAADTLAVRQKRRIYDITNVLEGIDLIEKKSKNSIQWKGVGAGCNTKEVIDRL 130

Query: 704 TQLKSEVEYLDNLINKVEEHKNKLKQSIANVTEDLDNQEYAYLTHTDLINMFENKTMLVI 525
             LK+E+E L+    ++++ K  L+QSI NV +D  N  ++Y+TH D+ N F   T+L I
Sbjct: 131 RYLKAEIEDLELKERELDQQKLWLQQSIKNVMDDSINNRFSYVTHEDICNCFNGDTLLAI 190

Query: 524 KAPQGTDVSVPLPEDPSASDAPRSLFSLKKSFQVHLKSHTTPISVLLVKQDELTSQPKLR 345
           +AP GT + VP+PE              +K +Q++LKSH+ PI VLL+ ++  +S+P + 
Sbjct: 191 QAPSGTQLEVPIPEMGQNG---------QKKYQINLKSHSGPIHVLLINKESSSSKPVVF 241

Query: 344 NVPFVDDINTNNDIKMT 294
            VP  DD+   +   +T
Sbjct: 242 PVPPPDDLTQPSSQSLT 258
>sp|Q61502|E2F5_MOUSE Transcription factor E2F5 (E2F-5)
          Length = 335

 Score =  170 bits (431), Expect = 4e-42
 Identities = 92/188 (48%), Positives = 125/188 (66%)
 Frame = -2

Query: 884 DGSLDLKIAAEYLAVRQKRRIYDITNVLEGIGLIEKKTKNSIQWKGGSAATNSPDMQQRQ 705
           DG LDLK AA+ LAVRQKRRIYDITNVLEGI LIEKK+KNSIQWKG  A  N+ ++  R 
Sbjct: 61  DGVLDLKAAADTLAVRQKRRIYDITNVLEGIDLIEKKSKNSIQWKGVGAGCNTKEVIDRL 120

Query: 704 TQLKSEVEYLDNLINKVEEHKNKLKQSIANVTEDLDNQEYAYLTHTDLINMFENKTMLVI 525
             LK+E+E L+    ++++ K  L+QSI NV ED  N  ++Y+TH D+ N F   T+L I
Sbjct: 121 RCLKAEIEDLELKERELDQQKLWLQQSIKNVMEDSINNRFSYVTHEDICNCFHGDTLLAI 180

Query: 524 KAPQGTDVSVPLPEDPSASDAPRSLFSLKKSFQVHLKSHTTPISVLLVKQDELTSQPKLR 345
           +AP GT + VP+PE              +K +Q++LKSH+ PI VLL+ ++  +S+P + 
Sbjct: 181 QAPSGTQLEVPIPEMGQNG---------QKKYQINLKSHSGPIHVLLINKESSSSKPVVF 231

Query: 344 NVPFVDDI 321
            VP  DD+
Sbjct: 232 PVPPPDDL 239
>sp|Q62814|E2F5_RAT Transcription factor E2F5 (E2F-5)
          Length = 300

 Score =  168 bits (425), Expect = 2e-41
 Identities = 91/188 (48%), Positives = 125/188 (66%)
 Frame = -2

Query: 884 DGSLDLKIAAEYLAVRQKRRIYDITNVLEGIGLIEKKTKNSIQWKGGSAATNSPDMQQRQ 705
           DG LDLK AA+ LAVRQKRRIYDITNVLEGI LIEKK+KNSIQWKG  A  N+ ++  R 
Sbjct: 26  DGVLDLKAAADTLAVRQKRRIYDITNVLEGIDLIEKKSKNSIQWKGVGAGCNTKEVIDRL 85

Query: 704 TQLKSEVEYLDNLINKVEEHKNKLKQSIANVTEDLDNQEYAYLTHTDLINMFENKTMLVI 525
             LK+E+E L+    ++++ K  L+QSI NV ED  N  ++Y+TH D+ + F   T+L I
Sbjct: 86  RCLKAEIEDLELKERELDQQKLWLQQSIKNVMEDSINNRFSYVTHEDICSCFNGDTLLAI 145

Query: 524 KAPQGTDVSVPLPEDPSASDAPRSLFSLKKSFQVHLKSHTTPISVLLVKQDELTSQPKLR 345
           +AP GT + VP+PE              +K +Q++LKSH+ PI VLL+ ++  +S+P + 
Sbjct: 146 QAPSGTQLEVPIPEMGQNG---------QKKYQINLKSHSGPIHVLLINKESNSSKPVVF 196

Query: 344 NVPFVDDI 321
            VP  DD+
Sbjct: 197 PVPPPDDL 204
>sp|O35261|E2F3_MOUSE Transcription factor E2F3 (E2F-3)
          Length = 457

 Score =  107 bits (268), Expect = 3e-23
 Identities = 92/271 (33%), Positives = 127/271 (46%), Gaps = 15/271 (5%)
 Frame = -2

Query: 884 DGSLDLKIAAEYLAVRQKRRIYDITNVLEGIGLIEKKTKNSIQWKGGSAATNSPDMQQRQ 705
           DG LDL  AAE L V QKRRIYDITNVLEGI LI+KK+KN++QW G S + +   + Q Q
Sbjct: 191 DGVLDLNKAAEVLKV-QKRRIYDITNVLEGIHLIKKKSKNNVQWMGCSLSEDGGMLAQCQ 249

Query: 704 TQLKSEVEYLDNLINKVEEHKNKLKQSIANVTEDLDNQEYAYLTHTDL--INMFENKTML 531
             L  EV  L     K++E        +  +TED +NQ  AY+T+ D+  I+  +++T++
Sbjct: 250 -GLSKEVTELSQEEKKLDELIQSCTLDLKLLTEDSENQRLAYVTYQDIRKISGLKDQTVI 308

Query: 530 VIKAPQGTDVSVPLPEDPSASDAPRSLFSLKKSFQVHLKSHTTPISVLLVKQDELTSQPK 351
           V+KAP  T + VP        D+  SL       Q+HL S   PI V L  ++  T +P 
Sbjct: 309 VVKAPPETRLEVP--------DSIESL-------QIHLASTQGPIEVYLCPEETETHRPM 353

Query: 350 LRN---------VPFVDDINTNN----DIKMTXXXXXXXXXXXXXXXXXXXEMEINXXXX 210
             N          P   D+ +NN    D  ++                   ++  N    
Sbjct: 354 KTNNQDHNGNIPKPTSKDLASNNSGHSDCSVSTANLSPLASPANLLQQTEDQIPSN---L 410

Query: 209 XXXXXXXXXXPCDGDYLLILDETEGACDMFD 117
                         DYLL L E EG  D+FD
Sbjct: 411 EGPFVNLLPPLLQEDYLLSLGEEEGISDLFD 441
>sp|O00716|E2F3_HUMAN Transcription factor E2F3 (E2F-3)
          Length = 465

 Score =  107 bits (266), Expect = 6e-23
 Identities = 75/183 (40%), Positives = 102/183 (55%), Gaps = 2/183 (1%)
 Frame = -2

Query: 884 DGSLDLKIAAEYLAVRQKRRIYDITNVLEGIGLIEKKTKNSIQWKGGSAATNSPDMQQRQ 705
           DG LDL  AAE L V QKRRIYDITNVLEGI LI+KK+KN++QW G S + +   + Q Q
Sbjct: 199 DGVLDLNKAAEVLKV-QKRRIYDITNVLEGIHLIKKKSKNNVQWMGCSLSEDGGMLAQCQ 257

Query: 704 TQLKSEVEYLDNLINKVEEHKNKLKQSIANVTEDLDNQEYAYLTHTDL--INMFENKTML 531
             L  EV  L     K++E        +  +TED +NQ  AY+T+ D+  I+  +++T++
Sbjct: 258 -GLSKEVTELSQEEKKLDELIQSCTLDLKLLTEDSENQRLAYVTYQDIRKISGLKDQTVI 316

Query: 530 VIKAPQGTDVSVPLPEDPSASDAPRSLFSLKKSFQVHLKSHTTPISVLLVKQDELTSQPK 351
           V+KAP  T + VP        D+  SL       Q+HL S   PI V L  ++  T  P 
Sbjct: 317 VVKAPPETRLEVP--------DSIESL-------QIHLASTQGPIEVYLCPEETETHSPM 361

Query: 350 LRN 342
             N
Sbjct: 362 KTN 364
>sp|P56931|E2F2_MOUSE Transcription factor E2F2 (E2F-2)
          Length = 443

 Score =  103 bits (256), Expect = 8e-22
 Identities = 68/173 (39%), Positives = 96/173 (55%), Gaps = 2/173 (1%)
 Frame = -2

Query: 884 DGSLDLKIAAEYLAVRQKRRIYDITNVLEGIGLIEKKTKNSIQWKGGSAATNSPDMQQRQ 705
           DG LDL  AAE L V QKRRIYDITNVLEGI LI KK+KN+IQW  G      P    RQ
Sbjct: 152 DGVLDLNWAAEVLDV-QKRRIYDITNVLEGIQLIRKKSKNNIQWV-GRELFEDPTRPSRQ 209

Query: 704 TQLKSEVEYLDNLINKVEEHKNKLKQSIANVTEDLDNQEYAYLTHTDL--INMFENKTML 531
            QL  E++ L N    +++       S  ++TED  N++ AY+T+ D+  +  F+ +T++
Sbjct: 210 QQLGQELKELMNAEQTLDQLIQSCSLSFKHLTEDNANKKLAYVTYQDIRAVGNFKEQTVI 269

Query: 530 VIKAPQGTDVSVPLPEDPSASDAPRSLFSLKKSFQVHLKSHTTPISVLLVKQD 372
            +KAP  T + VP                 +++ Q++LKS   PI V L  ++
Sbjct: 270 AVKAPPQTRLEVP--------------DRAEENLQIYLKSTQGPIEVYLCPEE 308
>sp|Q14209|E2F2_HUMAN Transcription factor E2F2 (E2F-2)
          Length = 437

 Score =  100 bits (249), Expect = 5e-21
 Identities = 67/173 (38%), Positives = 93/173 (53%), Gaps = 2/173 (1%)
 Frame = -2

Query: 884 DGSLDLKIAAEYLAVRQKRRIYDITNVLEGIGLIEKKTKNSIQWKGGSAATNSPDMQQRQ 705
           DG LDL  AAE L V QKRRIYDITNVLEGI LI KK KN+IQW  G      P    +Q
Sbjct: 150 DGVLDLNWAAEVLDV-QKRRIYDITNVLEGIQLIRKKAKNNIQWV-GRGMFEDPTRPGKQ 207

Query: 704 TQLKSEVEYLDNLINKVEEHKNKLKQSIANVTEDLDNQEYAYLTHTDL--INMFENKTML 531
            QL  E++ L N    +++       S  ++TED  N+  AY+T+ D+  +  F+ +T++
Sbjct: 208 QQLGQELKELMNTEQALDQLIQSCSLSFKHLTEDKANKRLAYVTYQDIRAVGNFKEQTVI 267

Query: 530 VIKAPQGTDVSVPLPEDPSASDAPRSLFSLKKSFQVHLKSHTTPISVLLVKQD 372
            +KAP  T + VP                 + + Q++LKS   PI V L  ++
Sbjct: 268 AVKAPPQTRLEVP--------------DRTEDNLQIYLKSTQGPIEVYLCPEE 306
>sp|O54917|E2F6_MOUSE Transcription factor E2F6 (E2F-6) (E2F-binding site-modulating
           activity protein) (EMA)
          Length = 272

 Score = 98.2 bits (243), Expect = 3e-20
 Identities = 62/179 (34%), Positives = 99/179 (55%), Gaps = 2/179 (1%)
 Frame = -2

Query: 881 GSLDLKIAAEYLAVRQKRRIYDITNVLEGIGLIEKKTKNSIQWKGGSAATNSPDMQQRQT 702
           G LDL   A  L+VR KRR+YDITNVL+GI L+EKK+KN I+W G     N+     +Q 
Sbjct: 85  GILDLNKVATKLSVR-KRRVYDITNVLDGIELVEKKSKNHIRWIGSD--LNNFGAAPQQK 141

Query: 701 QLKSEVEYLDNLINKVEEHKNKLKQSIANVTEDLDNQEYAYLTHTDL--INMFENKTMLV 528
           +L++E+  L  + + ++E      Q +  +T+D +N+  AY+T+ D+  I  F  + ++ 
Sbjct: 142 KLQAELSDLSAMEDALDELIKDCAQQLLELTDDKENERLAYVTYQDIHGIQAFHEQIVIA 201

Query: 527 IKAPQGTDVSVPLPEDPSASDAPRSLFSLKKSFQVHLKSHTTPISVLLVKQDELTSQPK 351
           +KAP+ T + VP P + S +              VH++S   PI V L + ++  S  K
Sbjct: 202 VKAPEETRLDVPApreDSIT--------------VHIRSTKGPIDVYLCEVEQNHSNGK 246
>sp|O75461|E2F6_HUMAN Transcription factor E2F6 (E2F-6)
          Length = 281

 Score = 95.9 bits (237), Expect = 1e-19
 Identities = 60/173 (34%), Positives = 94/173 (54%), Gaps = 2/173 (1%)
 Frame = -2

Query: 881 GSLDLKIAAEYLAVRQKRRIYDITNVLEGIGLIEKKTKNSIQWKGGSAATNSPDMQQRQT 702
           G LDL   A  L VR KRR+YDITNVL+GI L+EKK+KN I+W G   +      QQ+  
Sbjct: 85  GILDLNKVATKLGVR-KRRVYDITNVLDGIDLVEKKSKNHIRWIGSDLSNFGAVPQQK-- 141

Query: 701 QLKSEVEYLDNLINKVEEHKNKLKQSIANVTEDLDNQEYAYLTHTDL--INMFENKTMLV 528
           +L+ E+  L  + + ++E      Q +  +T+D +N+  AY+T+ D+  I  F  + ++ 
Sbjct: 142 KLQEELSDLSAMEDALDELIKDCAQQLFELTDDKENERLAYVTYQDIHSIQAFHEQIVIA 201

Query: 527 IKAPQGTDVSVPLPEDPSASDAPRSLFSLKKSFQVHLKSHTTPISVLLVKQDE 369
           +KAP  T + VP P + S +              VH++S   PI V L + ++
Sbjct: 202 VKAPAETRLDVPApreDSIT--------------VHIRSTNGPIDVYLCEVEQ 240
  Database: Non-redundant SwissProt sequences
    Posted date:  Dec 6, 2005  7:40 AM
  Number of letters in database: 68,354,980
  Number of sequences in database:  184,735
  
  Database: swissprot.01
    Posted date:  Dec 6, 2005  8:18 AM
  Number of letters in database: 66,202,850
  Number of sequences in database:  184,431
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 88,216,110
Number of Sequences: 369166
Number of extensions: 1660213
Number of successful extensions: 5317
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 5030
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5290
length of database: 68,354,980
effective HSP length: 110
effective length of database: 48,034,130
effective search space used: 8838279920
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)