Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= DrC_01470 (490 letters) Database: Non-redundant SwissProt sequences 184,735 sequences; 68,354,980 total letters Score E Sequences producing significant alignments: (bits) Value sp|O13811|PDI2_SCHPO Putative protein disulfide-isomerase C... 39 0.006 sp|P54399|PDI_DROME Protein disulfide-isomerase precursor (... 37 0.025 sp|P09102|PDIA1_CHICK Protein disulfide-isomerase precursor... 37 0.032 sp|P38661|PDIA6_MEDSA Probable protein disulfide-isomerase ... 35 0.072 sp|P07237|PDIA1_HUMAN Protein disulfide-isomerase precursor... 34 0.16 sp|P04785|PDIA1_RAT Protein disulfide-isomerase precursor (... 34 0.16 sp|Q5R5B6|PDIA1_PONPY Protein disulfide-isomerase precursor... 34 0.16 sp|P12244|GSBP_CHICK Dolichyl-diphosphooligosaccharide-prot... 34 0.16 sp|P05307|PDIA1_BOVIN Protein disulfide-isomerase precursor... 34 0.16 sp|P09103|PDIA1_MOUSE Protein disulfide-isomerase precursor... 34 0.21
>sp|O13811|PDI2_SCHPO Putative protein disulfide-isomerase C17H9.14c precursor Length = 359 Score = 38.9 bits (89), Expect = 0.006 Identities = 24/90 (26%), Positives = 37/90 (41%), Gaps = 7/90 (7%) Frame = +1 Query: 229 EPNKSTFVFIYAKWCRFSMAAAPIFNGLGRVF---PQLEFI---APAIKDFQEFKHTSYI 390 + K V YA WC + AP + LG+VF P +E + A D + Sbjct: 156 DDKKDVLVEFYADWCGYCKRLAPTYETLGKVFKNEPNVEIVKINADVFADIGRLHEVASF 215 Query: 391 PRIKMY-FGSKSVREFNGSDSDFDALVEFV 477 P IK + K E D ++L+E++ Sbjct: 216 PTIKFFPKDDKDKPELYEGDRSLESLIEYI 245
Score = 31.6 bits (70), Expect = 1.0 Identities = 24/92 (26%), Positives = 38/92 (41%), Gaps = 8/92 (8%) Frame = +1 Query: 238 KSTFVFIYAKWCRFSMAAAPIFNGLGRVFPQLEFI------APAIKDFQEFKHTSYIPRI 399 K + YA WC + AP++ LG +F + A D + H + P + Sbjct: 40 KGALIEFYATWCGHCKSLAPVYEELGALFEDHNDVLIGKIDADTHSDVADKYHITGFPTL 99 Query: 400 KMY--FGSKSVREFNGSDSDFDALVEFVYANT 489 + GS+ V+ N D D+L +FV T Sbjct: 100 IWFPPDGSEPVQYSNA--RDVDSLTQFVSEKT 129
>sp|P54399|PDI_DROME Protein disulfide-isomerase precursor (PDI) Length = 496 Score = 37.0 bits (84), Expect = 0.025 Identities = 38/124 (30%), Positives = 55/124 (44%), Gaps = 7/124 (5%) Frame = +1 Query: 136 VLQMDRPSEKDNIKAEMSSALNSSSEATKKNEPNKSTFVFIYAKWCRFSMAAAPIFNGLG 315 +L + P + D ++ + N S A K+ KS V YA WC API++ L Sbjct: 355 LLSQELPEDWDKNPVKVLVSSNFESVALDKS---KSVLVEFYAPWCGHCKQLAPIYDQLA 411 Query: 316 RVFPQLEFIAPAIKD-----FQEFKHTSYIPRIKMYFGSK--SVREFNGSDSDFDALVEF 474 + E I A D + K +S+ P IK YF + V +FN D D V+F Sbjct: 412 EKYKDNEDIVIAKMDSTANELESIKISSF-PTIK-YFRKEDNKVIDFN-LDRTLDDFVKF 468 Query: 475 VYAN 486 + AN Sbjct: 469 LDAN 472
>sp|P09102|PDIA1_CHICK Protein disulfide-isomerase precursor (PDI) (Prolyl 4-hydroxylase beta subunit) (Cellular thyroid hormone binding protein) (Retina cognin) (R-cognin) Length = 515 Score = 36.6 bits (83), Expect = 0.032 Identities = 26/81 (32%), Positives = 36/81 (44%), Gaps = 1/81 (1%) Frame = +1 Query: 121 GKI-PLVLQMDRPSEKDNIKAEMSSALNSSSEATKKNEPNKSTFVFIYAKWCRFSMAAAP 297 GKI P ++ D P + D ++ N A + NK+ FV YA WC AP Sbjct: 354 GKIKPHLMSQDLPEDWDKQPVKVLVGKNFEEVAF---DENKNVFVEFYAPWCGHCKQLAP 410 Query: 298 IFNGLGRVFPQLEFIAPAIKD 360 I++ LG + E I A D Sbjct: 411 IWDKLGETYRDHENIVIAKMD 431
>sp|P38661|PDIA6_MEDSA Probable protein disulfide-isomerase A6 precursor (P5) Length = 364 Score = 35.4 bits (80), Expect = 0.072 Identities = 23/86 (26%), Positives = 32/86 (37%), Gaps = 6/86 (6%) Frame = +1 Query: 238 KSTFVFIYAKWCRFSMAAAPIFNGLGRVFPQLEFI------APAIKDFQEFKHTSYIPRI 399 K V YA WC + API+ + VF + + A +D E S P + Sbjct: 166 KDVLVEFYAPWCGHCKSLAPIYEKVAAVFKSEDDVVIANLDADKYRDLAEKYDVSGFPTL 225 Query: 400 KMYFGSKSVREFNGSDSDFDALVEFV 477 K + E G D D V F+ Sbjct: 226 KFFPKGNKAGEDYGGGRDLDDFVAFI 251
>sp|P07237|PDIA1_HUMAN Protein disulfide-isomerase precursor (PDI) (Prolyl 4-hydroxylase beta subunit) (Cellular thyroid hormone binding protein) (p55) Length = 508 Score = 34.3 bits (77), Expect = 0.16 Identities = 31/114 (27%), Positives = 48/114 (42%), Gaps = 7/114 (6%) Frame = +1 Query: 121 GKI-PLVLQMDRPSEKDNIKAEMSSALNSSSEATKKNEPNKSTFVFIYAKWCRFSMAAAP 297 GKI P ++ + P + D ++ N A + K+ FV YA WC AP Sbjct: 349 GKIKPHLMSQELPEDWDKQPVKVLVGKNFEDVAF---DEKKNVFVEFYAPWCGHCKQLAP 405 Query: 298 IFNGLGRVFPQLEFIAPAIKDFQ----EFKHTSYIPRIKMYFGS--KSVREFNG 441 I++ LG + E I A D E P +K + S ++V ++NG Sbjct: 406 IWDKLGETYKDHENIVIAKMDSTANEVEAVKVHSFPTLKFFPASADRTVIDYNG 459
>sp|P04785|PDIA1_RAT Protein disulfide-isomerase precursor (PDI) (Prolyl 4-hydroxylase beta subunit) (Cellular thyroid hormone binding protein) Length = 509 Score = 34.3 bits (77), Expect = 0.16 Identities = 31/114 (27%), Positives = 48/114 (42%), Gaps = 7/114 (6%) Frame = +1 Query: 121 GKI-PLVLQMDRPSEKDNIKAEMSSALNSSSEATKKNEPNKSTFVFIYAKWCRFSMAAAP 297 GKI P ++ + P + D ++ N A + K+ FV YA WC AP Sbjct: 351 GKIKPHLMSQELPEDWDKQPVKVLVGKNFEEVAF---DEKKNVFVEFYAPWCGHCKQLAP 407 Query: 298 IFNGLGRVFPQLEFIAPAIKDFQ----EFKHTSYIPRIKMYFGS--KSVREFNG 441 I++ LG + E I A D E P +K + S ++V ++NG Sbjct: 408 IWDKLGETYKDHENIVIAKMDSTANEVEAVKVHSFPTLKFFPASADRTVIDYNG 461
>sp|Q5R5B6|PDIA1_PONPY Protein disulfide-isomerase precursor (PDI) (Prolyl 4-hydroxylase beta subunit) Length = 508 Score = 34.3 bits (77), Expect = 0.16 Identities = 31/114 (27%), Positives = 48/114 (42%), Gaps = 7/114 (6%) Frame = +1 Query: 121 GKI-PLVLQMDRPSEKDNIKAEMSSALNSSSEATKKNEPNKSTFVFIYAKWCRFSMAAAP 297 GKI P ++ + P + D ++ N A + K+ FV YA WC AP Sbjct: 349 GKIKPHLMSQELPDDWDKQPVKVLVGKNFEDVAF---DEKKNVFVEFYAPWCGHCKQLAP 405 Query: 298 IFNGLGRVFPQLEFIAPAIKDFQ----EFKHTSYIPRIKMYFGS--KSVREFNG 441 I++ LG + E I A D E P +K + S ++V ++NG Sbjct: 406 IWDKLGETYKDHENIVIAKMDSTANEVEAVKVHSFPTLKFFPASADRTVIDYNG 459
>sp|P12244|GSBP_CHICK Dolichyl-diphosphooligosaccharide-protein glycotransferase precursor (Glycosylation site-binding chain) (GSBP) Length = 508 Score = 34.3 bits (77), Expect = 0.16 Identities = 30/114 (26%), Positives = 51/114 (44%), Gaps = 7/114 (6%) Frame = +1 Query: 121 GKIPLVLQMDRPSEKDNIKAEMSSALNSSSEATKKNEPNKSTFVFIYAKWCRFSMAAAPI 300 GKI L + P +D K + + + E +E K+ F+ YA WC AP+ Sbjct: 349 GKIKPHLMSNEPLPEDWDKQPVKVLVGKNYEEVAFDE-KKNVFIEFYAPWCGHCKQLAPM 407 Query: 301 FNGLGRVFPQLEFIAPA-----IKDFQEFKHTSYIPRIKMYFGS--KSVREFNG 441 ++ LG + E I A + + K S+ P +K + S ++V ++NG Sbjct: 408 WDRLGEAYKDDENIVIAKMESTANEVEAIKVHSF-PTLKFFPASAERTVIDYNG 460
>sp|P05307|PDIA1_BOVIN Protein disulfide-isomerase precursor (PDI) (Prolyl 4-hydroxylase beta subunit) (Cellular thyroid hormone binding protein) (p55) Length = 510 Score = 34.3 bits (77), Expect = 0.16 Identities = 31/114 (27%), Positives = 48/114 (42%), Gaps = 7/114 (6%) Frame = +1 Query: 121 GKI-PLVLQMDRPSEKDNIKAEMSSALNSSSEATKKNEPNKSTFVFIYAKWCRFSMAAAP 297 GKI P ++ + P + D ++ N A + K+ FV YA WC AP Sbjct: 351 GKIKPHLMSQELPDDWDKQPVKVLVGKNFEEVAF---DEKKNVFVEFYAPWCGHCKQLAP 407 Query: 298 IFNGLGRVFPQLEFIAPAIKDFQ----EFKHTSYIPRIKMYFGS--KSVREFNG 441 I++ LG + E I A D E P +K + S ++V ++NG Sbjct: 408 IWDKLGETYKDHENIVIAKMDSTANEVEAVKVHSFPTLKFFPASADRTVIDYNG 461
>sp|P09103|PDIA1_MOUSE Protein disulfide-isomerase precursor (PDI) (Prolyl 4-hydroxylase beta subunit) (Cellular thyroid hormone binding protein) (p55) (Erp59) Length = 509 Score = 33.9 bits (76), Expect = 0.21 Identities = 31/114 (27%), Positives = 48/114 (42%), Gaps = 7/114 (6%) Frame = +1 Query: 121 GKI-PLVLQMDRPSEKDNIKAEMSSALNSSSEATKKNEPNKSTFVFIYAKWCRFSMAAAP 297 GKI P ++ + P + D ++ N A + K+ FV YA WC AP Sbjct: 351 GKIKPHLMSQEVPEDWDKQPVKVLVGANFEEVAF---DEKKNVFVEFYAPWCGHCKQLAP 407 Query: 298 IFNGLGRVFPQLEFIAPAIKDFQ----EFKHTSYIPRIKMYFGS--KSVREFNG 441 I++ LG + E I A D E P +K + S ++V ++NG Sbjct: 408 IWDKLGETYKDHENIIIAKMDSTANEVEAVKVHSFPTLKFFPASADRTVIDYNG 461
Database: Non-redundant SwissProt sequences Posted date: Dec 6, 2005 7:40 AM Number of letters in database: 68,354,980 Number of sequences in database: 184,735 Database: swissprot.01 Posted date: Dec 6, 2005 8:18 AM Number of letters in database: 66,202,850 Number of sequences in database: 184,431 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 53,975,087 Number of Sequences: 369166 Number of extensions: 1018409 Number of successful extensions: 3303 Number of sequences better than 10.0: 10 Number of HSP's better than 10.0 without gapping: 3267 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 3303 length of database: 68,354,980 effective HSP length: 102 effective length of database: 49,512,010 effective search space used: 2970720600 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)