Planaria EST Database


DrC_01466

BLASTX 2.2.13 [Nov-27-2005]

Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= DrC_01466
         (705 letters)

Database: Non-redundant SwissProt sequences 
           184,735 sequences; 68,354,980 total letters



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

sp|P42687|SPK1_DUGTI  Tyrosine-protein kinase SPK-1               339   4e-93
sp|Q07014|LYN_RAT  Tyrosine-protein kinase Lyn                    192   6e-49
sp|P25911|LYN_MOUSE  Tyrosine-protein kinase Lyn                  192   7e-49
sp|P07948|LYN_HUMAN  Tyrosine-protein kinase Lyn                  191   2e-48
sp|Q95KR7|LCK_SAISC  Proto-oncogene tyrosine-protein kinase ...   191   2e-48
sp|P50545|HCK_RAT  Tyrosine-protein kinase HCK (p56-HCK) (He...   190   4e-48
sp|P08103|HCK_MOUSE  Tyrosine-protein kinase HCK (p56-HCK/p5...   190   4e-48
sp|P08631|HCK_HUMAN  Tyrosine-protein kinase HCK (p59-HCK/p6...   188   1e-47
sp|P42683|LCK_CHICK  Proto-oncogene tyrosine-protein kinase ...   188   1e-47
sp|P00526|SRC_RSVP  Tyrosine-protein kinase transforming pro...   187   2e-47
>sp|P42687|SPK1_DUGTI Tyrosine-protein kinase SPK-1
          Length = 497

 Score =  339 bits (870), Expect = 4e-93
 Identities = 164/210 (78%), Positives = 183/210 (87%)
 Frame = +3

Query: 3   MPMIIIVEFMKNGSLKEYLKSEDGKQIILSQMIHMMAEISEGMAYLEGEKVVHRDLRADN 182
           MPM+IIVE+MKNGSLKEYLK+ DGK+  L+QM+HMMAEISEGMAYLE EKVVHRDLRADN
Sbjct: 288 MPMLIIVEYMKNGSLKEYLKTPDGKKTNLNQMVHMMAEISEGMAYLESEKVVHRDLRADN 347

Query: 183 ILVADDLTVKVADFGLTELTEGNNDSQEKKNLRFPYKWTAPEAAKTKIFTSKSDVWSFGI 362
           ILVA+DLT KVADFGLTELT+G+   QEKK LRFPYKWTAPEAAK+K+FTSKSDVWS+GI
Sbjct: 348 ILVANDLTRKVADFGLTELTDGSLGDQEKKTLRFPYKWTAPEAAKSKVFTSKSDVWSYGI 407

Query: 363 VMYEILTWASPPYPDTPAKEVIDKVSSGYRMPNPEKFIPGARCPDEIYKIMLNCWNVLPE 542
           VM+EILTWAS PYPD PAKEVI+KVS GYRMPNPEKFI G  CPDEIYKIM+ CW+  PE
Sbjct: 408 VMFEILTWASSPYPDIPAKEVIEKVSKGYRMPNPEKFITGVCCPDEIYKIMIWCWDANPE 467

Query: 543 ERPTFASLQEQMDTLIVDNTGSGTYYSQSK 632
           +RPTF  LQE+MD LIVD   +  YYS SK
Sbjct: 468 KRPTFLVLQEKMDLLIVDTLTNNAYYSHSK 497
>sp|Q07014|LYN_RAT Tyrosine-protein kinase Lyn
          Length = 512

 Score =  192 bits (489), Expect = 6e-49
 Identities = 95/200 (47%), Positives = 129/200 (64%)
 Frame = +3

Query: 6   PMIIIVEFMKNGSLKEYLKSEDGKQIILSQMIHMMAEISEGMAYLEGEKVVHRDLRADNI 185
           P+ II EFM  GSL ++LKS++G +++L ++I   A+I+EGMAY+E +  +HRDLRA N+
Sbjct: 314 PIYIITEFMAKGSLLDFLKSDEGSKVLLPKLIDFSAQIAEGMAYIERKNYIHRDLRAANV 373

Query: 186 LVADDLTVKVADFGLTELTEGNNDSQEKKNLRFPYKWTAPEAAKTKIFTSKSDVWSFGIV 365
           LV++ L  K+ADFGL  + E +N+   ++  +FP KWTAPEA     FT KSDVWSFGI+
Sbjct: 374 LVSESLMCKIADFGLARVIE-DNEYTAREGAKFPIKWTAPEAINFGCFTIKSDVWSFGIL 432

Query: 366 MYEILTWASPPYPDTPAKEVIDKVSSGYRMPNPEKFIPGARCPDEIYKIMLNCWNVLPEE 545
           +YEI+T+   PYP     +V+  +S GYRMP  E       CPDE+Y IM  CW    EE
Sbjct: 433 LYEIVTYGKIPYPGRTNADVMTALSQGYRMPRME------NCPDELYDIMKMCWKESAEE 486

Query: 546 RPTFASLQEQMDTLIVDNTG 605
           RPTF  LQ  +D       G
Sbjct: 487 RPTFDYLQSVLDDFYTATEG 506
>sp|P25911|LYN_MOUSE Tyrosine-protein kinase Lyn
          Length = 512

 Score =  192 bits (488), Expect = 7e-49
 Identities = 95/200 (47%), Positives = 129/200 (64%)
 Frame = +3

Query: 6   PMIIIVEFMKNGSLKEYLKSEDGKQIILSQMIHMMAEISEGMAYLEGEKVVHRDLRADNI 185
           P+ II EFM  GSL ++LKS++G +++L ++I   A+I+EGMAY+E +  +HRDLRA N+
Sbjct: 314 PIYIITEFMAKGSLLDFLKSDEGGKVLLPKLIDFSAQIAEGMAYIERKNYIHRDLRAANV 373

Query: 186 LVADDLTVKVADFGLTELTEGNNDSQEKKNLRFPYKWTAPEAAKTKIFTSKSDVWSFGIV 365
           LV++ L  K+ADFGL  + E +N+   ++  +FP KWTAPEA     FT KSDVWSFGI+
Sbjct: 374 LVSESLMCKIADFGLARVIE-DNEYTAREGAKFPIKWTAPEAINFGCFTIKSDVWSFGIL 432

Query: 366 MYEILTWASPPYPDTPAKEVIDKVSSGYRMPNPEKFIPGARCPDEIYKIMLNCWNVLPEE 545
           +YEI+T+   PYP     +V+  +S GYRMP  E       CPDE+Y IM  CW    EE
Sbjct: 433 LYEIVTYGKIPYPGRTNADVMSALSQGYRMPRME------NCPDELYDIMKMCWKEKAEE 486

Query: 546 RPTFASLQEQMDTLIVDNTG 605
           RPTF  LQ  +D       G
Sbjct: 487 RPTFDYLQSVLDDFYTATEG 506
>sp|P07948|LYN_HUMAN Tyrosine-protein kinase Lyn
          Length = 512

 Score =  191 bits (484), Expect = 2e-48
 Identities = 94/200 (47%), Positives = 129/200 (64%)
 Frame = +3

Query: 6   PMIIIVEFMKNGSLKEYLKSEDGKQIILSQMIHMMAEISEGMAYLEGEKVVHRDLRADNI 185
           P+ II E+M  GSL ++LKS++G +++L ++I   A+I+EGMAY+E +  +HRDLRA N+
Sbjct: 314 PIYIITEYMAKGSLLDFLKSDEGGKVLLPKLIDFSAQIAEGMAYIERKNYIHRDLRAANV 373

Query: 186 LVADDLTVKVADFGLTELTEGNNDSQEKKNLRFPYKWTAPEAAKTKIFTSKSDVWSFGIV 365
           LV++ L  K+ADFGL  + E +N+   ++  +FP KWTAPEA     FT KSDVWSFGI+
Sbjct: 374 LVSESLMCKIADFGLARVIE-DNEYTAREGAKFPIKWTAPEAINFGCFTIKSDVWSFGIL 432

Query: 366 MYEILTWASPPYPDTPAKEVIDKVSSGYRMPNPEKFIPGARCPDEIYKIMLNCWNVLPEE 545
           +YEI+T+   PYP     +V+  +S GYRMP  E       CPDE+Y IM  CW    EE
Sbjct: 433 LYEIVTYGKIPYPGRTNADVMTALSQGYRMPRVE------NCPDELYDIMKMCWKEKAEE 486

Query: 546 RPTFASLQEQMDTLIVDNTG 605
           RPTF  LQ  +D       G
Sbjct: 487 RPTFDYLQSVLDDFYTATEG 506
>sp|Q95KR7|LCK_SAISC Proto-oncogene tyrosine-protein kinase LCK (p56-LCK) (Lymphocyte
           cell-specific protein-tyrosine kinase)
          Length = 509

 Score =  191 bits (484), Expect = 2e-48
 Identities = 93/200 (46%), Positives = 130/200 (65%)
 Frame = +3

Query: 6   PMIIIVEFMKNGSLKEYLKSEDGKQIILSQMIHMMAEISEGMAYLEGEKVVHRDLRADNI 185
           P+ II E+M+NGSL ++LK+  G ++ +++++ M A+I EGMA+LE    +HRDLRA NI
Sbjct: 311 PIYIITEYMENGSLVDFLKTPSGIKLTINKLLDMAAQIVEGMAFLEERNYIHRDLRAANI 370

Query: 186 LVADDLTVKVADFGLTELTEGNNDSQEKKNLRFPYKWTAPEAAKTKIFTSKSDVWSFGIV 365
           LV+D L+ K+ADFGL  L E +N+   ++  +FP KWTAPEA     FT KSDVWSFGI+
Sbjct: 371 LVSDTLSCKIADFGLARLIE-DNEYTAREGAKFPIKWTAPEAINYGTFTIKSDVWSFGIL 429

Query: 366 MYEILTWASPPYPDTPAKEVIDKVSSGYRMPNPEKFIPGARCPDEIYKIMLNCWNVLPEE 545
           M EI+T    PYP     EVI  +  GYRMP P+       CP+E+YK+M+ CW   P++
Sbjct: 430 MTEIVTHGRIPYPGMTNPEVIQNLERGYRMPRPD------NCPEELYKLMMQCWRERPDD 483

Query: 546 RPTFASLQEQMDTLIVDNTG 605
           RPTF  L+  ++       G
Sbjct: 484 RPTFDYLRSVLEDFFTATEG 503
>sp|P50545|HCK_RAT Tyrosine-protein kinase HCK (p56-HCK) (Hemopoietic cell kinase)
          Length = 503

 Score =  190 bits (482), Expect = 4e-48
 Identities = 94/192 (48%), Positives = 125/192 (65%)
 Frame = +3

Query: 6   PMIIIVEFMKNGSLKEYLKSEDGKQIILSQMIHMMAEISEGMAYLEGEKVVHRDLRADNI 185
           P+ I+ EFM  GSL ++LKSE+G +  L ++I   A+ISEGMA++E    +HRDLRA NI
Sbjct: 305 PIFIVTEFMAKGSLLDFLKSEEGSKQPLPKLIDFSAQISEGMAFIEQRNYIHRDLRAANI 364

Query: 186 LVADDLTVKVADFGLTELTEGNNDSQEKKNLRFPYKWTAPEAAKTKIFTSKSDVWSFGIV 365
           LV+  L  K+ADFGL  + E +N+   ++  +FP KWTAPEA     FT KSDVWSFGI+
Sbjct: 365 LVSASLVCKIADFGLARIIE-DNEYTAREGAKFPIKWTAPEAINFGSFTIKSDVWSFGIL 423

Query: 366 MYEILTWASPPYPDTPAKEVIDKVSSGYRMPNPEKFIPGARCPDEIYKIMLNCWNVLPEE 545
           + EI+T+   PYP     EVI  +  GYRMP P+       CP+E+Y IM+ CW   PEE
Sbjct: 424 LMEIVTYGRIPYPGMSNPEVIRALEHGYRMPRPD------NCPEELYSIMIRCWKNRPEE 477

Query: 546 RPTFASLQEQMD 581
           RPTF  +Q  +D
Sbjct: 478 RPTFEYIQSVLD 489
>sp|P08103|HCK_MOUSE Tyrosine-protein kinase HCK (p56-HCK/p59-HCK) (Hemopoietic cell
           kinase) (B-cell/myeloid kinase) (BMK)
          Length = 524

 Score =  190 bits (482), Expect = 4e-48
 Identities = 94/192 (48%), Positives = 125/192 (65%)
 Frame = +3

Query: 6   PMIIIVEFMKNGSLKEYLKSEDGKQIILSQMIHMMAEISEGMAYLEGEKVVHRDLRADNI 185
           P+ I+ EFM  GSL ++LKSE+G +  L ++I   A+ISEGMA++E    +HRDLRA NI
Sbjct: 326 PIFIVTEFMAKGSLLDFLKSEEGSKQPLPKLIDFSAQISEGMAFIEQRNYIHRDLRAANI 385

Query: 186 LVADDLTVKVADFGLTELTEGNNDSQEKKNLRFPYKWTAPEAAKTKIFTSKSDVWSFGIV 365
           LV+  L  K+ADFGL  + E +N+   ++  +FP KWTAPEA     FT KSDVWSFGI+
Sbjct: 386 LVSASLVCKIADFGLARIIE-DNEYTAREGAKFPIKWTAPEAINFGSFTIKSDVWSFGIL 444

Query: 366 MYEILTWASPPYPDTPAKEVIDKVSSGYRMPNPEKFIPGARCPDEIYKIMLNCWNVLPEE 545
           + EI+T+   PYP     EVI  +  GYRMP P+       CP+E+Y IM+ CW   PEE
Sbjct: 445 LMEIVTYGRIPYPGMSNPEVIRALEHGYRMPRPD------NCPEELYNIMIRCWKNRPEE 498

Query: 546 RPTFASLQEQMD 581
           RPTF  +Q  +D
Sbjct: 499 RPTFEYIQSVLD 510
>sp|P08631|HCK_HUMAN Tyrosine-protein kinase HCK (p59-HCK/p60-HCK) (Hemopoietic cell
           kinase)
          Length = 526

 Score =  188 bits (478), Expect = 1e-47
 Identities = 94/192 (48%), Positives = 125/192 (65%)
 Frame = +3

Query: 6   PMIIIVEFMKNGSLKEYLKSEDGKQIILSQMIHMMAEISEGMAYLEGEKVVHRDLRADNI 185
           P+ II EFM  GSL ++LKS++G +  L ++I   A+I+EGMA++E    +HRDLRA NI
Sbjct: 328 PIYIITEFMAKGSLLDFLKSDEGSKQPLPKLIDFSAQIAEGMAFIEQRNYIHRDLRAANI 387

Query: 186 LVADDLTVKVADFGLTELTEGNNDSQEKKNLRFPYKWTAPEAAKTKIFTSKSDVWSFGIV 365
           LV+  L  K+ADFGL  + E +N+   ++  +FP KWTAPEA     FT KSDVWSFGI+
Sbjct: 388 LVSASLVCKIADFGLARVIE-DNEYTAREGAKFPIKWTAPEAINFGSFTIKSDVWSFGIL 446

Query: 366 MYEILTWASPPYPDTPAKEVIDKVSSGYRMPNPEKFIPGARCPDEIYKIMLNCWNVLPEE 545
           + EI+T+   PYP     EVI  +  GYRMP PE       CP+E+Y IM+ CW   PEE
Sbjct: 447 LMEIVTYGRIPYPGMSNPEVIRALERGYRMPRPE------NCPEELYNIMMRCWKNRPEE 500

Query: 546 RPTFASLQEQMD 581
           RPTF  +Q  +D
Sbjct: 501 RPTFEYIQSVLD 512
>sp|P42683|LCK_CHICK Proto-oncogene tyrosine-protein kinase LCK (Protein-tyrosine kinase
           C-TKL) (p56tk1)
          Length = 508

 Score =  188 bits (477), Expect = 1e-47
 Identities = 89/200 (44%), Positives = 131/200 (65%)
 Frame = +3

Query: 6   PMIIIVEFMKNGSLKEYLKSEDGKQIILSQMIHMMAEISEGMAYLEGEKVVHRDLRADNI 185
           P+ II E+M+ GSL ++LK+ +G ++ +++++ M A+I+EGMA++E +  +HRDLRA NI
Sbjct: 310 PIYIITEYMEKGSLVDFLKTSEGIKLSINKLLDMAAQIAEGMAFIEAKNYIHRDLRAANI 369

Query: 186 LVADDLTVKVADFGLTELTEGNNDSQEKKNLRFPYKWTAPEAAKTKIFTSKSDVWSFGIV 365
           LV++ L  K+ADFGL  L E +N+   ++  +FP KWTAPEA     FT KSDVWSFGI+
Sbjct: 370 LVSEALCCKIADFGLARLIE-DNEYTAREGAKFPIKWTAPEAINYGTFTIKSDVWSFGIL 428

Query: 366 MYEILTWASPPYPDTPAKEVIDKVSSGYRMPNPEKFIPGARCPDEIYKIMLNCWNVLPEE 545
           + EI+T+   PYP     EVI  +  GYRMP P+       CP E+Y++M+ CW   PEE
Sbjct: 429 LTEIVTYGRIPYPGMTNPEVIQNLERGYRMPQPD------NCPQELYELMMQCWKEQPEE 482

Query: 546 RPTFASLQEQMDTLIVDNTG 605
           RPTF  ++  ++       G
Sbjct: 483 RPTFEYMKSVLEDFFTATEG 502
>sp|P00526|SRC_RSVP Tyrosine-protein kinase transforming protein Src (p60-Src) (v-Src)
           (pp60v-src)
          Length = 526

 Score =  187 bits (476), Expect = 2e-47
 Identities = 95/191 (49%), Positives = 126/191 (65%)
 Frame = +3

Query: 6   PMIIIVEFMKNGSLKEYLKSEDGKQIILSQMIHMMAEISEGMAYLEGEKVVHRDLRADNI 185
           P+ I++E+M  GSL ++LK E GK + L Q++ M A+I+ GMAY+E    VHRDLRA NI
Sbjct: 333 PIYIVIEYMSKGSLLDFLKGEMGKYLRLPQLVDMAAQIASGMAYVERMNYVHRDLRAANI 392

Query: 186 LVADDLTVKVADFGLTELTEGNNDSQEKKNLRFPYKWTAPEAAKTKIFTSKSDVWSFGIV 365
           LV ++L  KVADFGL  L E +N+   ++  +FP KWTAPEAA    FT KSDVWSFGI+
Sbjct: 393 LVGENLVCKVADFGLARLIE-DNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGIL 451

Query: 366 MYEILTWASPPYPDTPAKEVIDKVSSGYRMPNPEKFIPGARCPDEIYKIMLNCWNVLPEE 545
           + E+ T    PYP    +EV+D+V  GYRMP P +      CP+ ++ +M  CW   PEE
Sbjct: 452 LTELTTKGRVPYPGMVNREVLDQVERGYRMPCPPE------CPESLHDLMCQCWRKDPEE 505

Query: 546 RPTFASLQEQM 578
           RPTF  LQ Q+
Sbjct: 506 RPTFKYLQAQL 516
  Database: Non-redundant SwissProt sequences
    Posted date:  Dec 6, 2005  7:40 AM
  Number of letters in database: 68,354,980
  Number of sequences in database:  184,735
  
  Database: swissprot.01
    Posted date:  Dec 6, 2005  8:18 AM
  Number of letters in database: 66,202,850
  Number of sequences in database:  184,431
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 80,591,189
Number of Sequences: 369166
Number of extensions: 1656809
Number of successful extensions: 8090
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 6066
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 6303
length of database: 68,354,980
effective HSP length: 107
effective length of database: 48,588,335
effective search space used: 6170718545
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)