Planaria EST Database


DrC_01394

BLASTX 2.2.13 [Nov-27-2005]

Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= DrC_01394
         (835 letters)

Database: Non-redundant SwissProt sequences 
           184,735 sequences; 68,354,980 total letters



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

sp|Q9EQH3|VPS35_MOUSE  Vacuolar protein sorting 35 (Vesicle ...   284   2e-76
sp|Q96QK1|VPS35_HUMAN  Vacuolar protein sorting 35 (Vesicle ...   284   2e-76
sp|P34110|VPS35_YEAST  Vacuolar protein sorting-associated p...   136   8e-32
sp|O74552|VPS35_SCHPO  Vacuolar protein sorting-associated p...   132   9e-31
sp|Q58611|YC14_METJA  Hypothetical protein MJ1214                  34   0.43 
sp|Q8TDY2|RBCC1_HUMAN  RB1-inducible coiled-coil protein 1         34   0.57 
sp|Q859W7|YCF2_ANTFO  Protein ycf2                                 32   1.7  
sp|O60566|BUB1B_HUMAN  Mitotic checkpoint serine/threonine-p...    32   2.8  
sp|Q61098|IL18R_MOUSE  Interleukin-18 receptor 1 precursor (...    31   4.8  
sp|Q8TMT1|DNLI_METAC  DNA ligase (Polydeoxyribonucleotide sy...    30   6.3  
>sp|Q9EQH3|VPS35_MOUSE Vacuolar protein sorting 35 (Vesicle protein sorting 35)
            (Maternal-embryonic 3)
          Length = 796

 Score =  284 bits (727), Expect = 2e-76
 Identities = 137/278 (49%), Positives = 198/278 (71%)
 Frame = +2

Query: 2    FL*MNKLWVRMQHQGHTXXXXXXXXXXXXXXXXVGTNLNRLSQLESIDVERYKTTVLPAV 181
            F  MNKLWVRMQHQGH+                VGTNL RLSQLE ++VERYK  VL  +
Sbjct: 187  FAEMNKLWVRMQHQGHSRDREKRERERQELRILVGTNLVRLSQLEGVNVERYKQIVLTGI 246

Query: 182  LEQIVNCHDAIAQEYLMDVVIQVFPDEFHLETLETLLRATSELEPNVHIKSIIGALIERL 361
            LEQ+VNC DA+AQEYLM+ +IQVFPDEFHL+TL   LRA +EL  NV++K+II ALI+RL
Sbjct: 247  LEQVVNCRDALAQEYLMECIIQVFPDEFHLQTLNPFLRACAELHQNVNVKNIIIALIDRL 306

Query: 362  SQYATEESGTGIPDSIPLFDIFSREVNSMVERRKDLPPEDIMSLEASLLHLALKVYPNKL 541
            + +A  E G GIP  I LFDIFS++V ++++ R+D+P ED++SL+ SL++LA+K YP+++
Sbjct: 307  ALFAHREDGPGIPAEIKLFDIFSQQVATVIQSRQDMPSEDVVSLQVSLINLAMKCYPDRV 366

Query: 542  ELVDNVVKGATEALRNMNISKISYSSCLSRELIRLLKMPIDVYKDIRIILKLENYSDLIQ 721
            + VD V++   E    +N+  I+ SS +S+EL RLLK+P+D Y +I  +LKL+++  L +
Sbjct: 367  DYVDKVLETTVEIFNKLNLEHIATSSAVSKELTRLLKIPVDTYNNILTVLKLKHFHPLFE 426

Query: 722  NLEYNGRKLISCHLLTNTLDQNHVLNTEEQLDSLFKCI 835
              +Y  RK +SC++L+N LD N  + +++Q+DS+   +
Sbjct: 427  YFDYESRKSMSCYVLSNVLDYNTEIVSQDQVDSIMNLV 464
>sp|Q96QK1|VPS35_HUMAN Vacuolar protein sorting 35 (Vesicle protein sorting 35) (hVPS35)
            (Maternal-embryonic 3)
          Length = 796

 Score =  284 bits (727), Expect = 2e-76
 Identities = 137/278 (49%), Positives = 198/278 (71%)
 Frame = +2

Query: 2    FL*MNKLWVRMQHQGHTXXXXXXXXXXXXXXXXVGTNLNRLSQLESIDVERYKTTVLPAV 181
            F  MNKLWVRMQHQGH+                VGTNL RLSQLE ++VERYK  VL  +
Sbjct: 187  FAEMNKLWVRMQHQGHSRDREKRERERQELRILVGTNLVRLSQLEGVNVERYKQIVLTGI 246

Query: 182  LEQIVNCHDAIAQEYLMDVVIQVFPDEFHLETLETLLRATSELEPNVHIKSIIGALIERL 361
            LEQ+VNC DA+AQEYLM+ +IQVFPDEFHL+TL   LRA +EL  NV++K+II ALI+RL
Sbjct: 247  LEQVVNCRDALAQEYLMECIIQVFPDEFHLQTLNPFLRACAELHQNVNVKNIIIALIDRL 306

Query: 362  SQYATEESGTGIPDSIPLFDIFSREVNSMVERRKDLPPEDIMSLEASLLHLALKVYPNKL 541
            + +A  E G GIP  I LFDIFS++V ++++ R+D+P ED++SL+ SL++LA+K YP+++
Sbjct: 307  ALFAHREDGPGIPADIKLFDIFSQQVATVIQSRQDMPSEDVVSLQVSLINLAMKCYPDRV 366

Query: 542  ELVDNVVKGATEALRNMNISKISYSSCLSRELIRLLKMPIDVYKDIRIILKLENYSDLIQ 721
            + VD V++   E    +N+  I+ SS +S+EL RLLK+P+D Y +I  +LKL+++  L +
Sbjct: 367  DYVDKVLETTVEIFNKLNLEHIATSSAVSKELTRLLKIPVDTYNNILTVLKLKHFHPLFE 426

Query: 722  NLEYNGRKLISCHLLTNTLDQNHVLNTEEQLDSLFKCI 835
              +Y  RK +SC++L+N LD N  + +++Q+DS+   +
Sbjct: 427  YFDYESRKSMSCYVLSNVLDYNTEIVSQDQVDSIMNLV 464
>sp|P34110|VPS35_YEAST Vacuolar protein sorting-associated protein VPS35
          Length = 944

 Score =  136 bits (342), Expect = 8e-32
 Identities = 75/213 (35%), Positives = 116/213 (54%), Gaps = 7/213 (3%)
 Frame = +2

Query: 2   FL*MNKLWVRMQHQGHTXXXXXXXXXXXXXXXXVGTNLNRLSQLESIDVERYKTTVLPAV 181
           F+ MNKLWVR+QHQG                  VG+ L RLSQ+   + + YK  +LP +
Sbjct: 168 FIEMNKLWVRLQHQGPLRERETRTRERKELQILVGSQLVRLSQIIDDNFQMYKQDILPTI 227

Query: 182 LEQIVNCHDAIAQEYLMDVVIQVFPDEFHLETLETLLRATSELEPNVHIKSIIGALIERL 361
           LEQ++ C D ++QEYL+DV+ QVF DEFHL+TL+TLL+ T  L P+V I  I+  L++RL
Sbjct: 228 LEQVIQCRDLVSQEYLLDVICQVFADEFHLKTLDTLLQTTLHLNPDVSINKIVLTLVDRL 287

Query: 362 SQYATEE-------SGTGIPDSIPLFDIFSREVNSMVERRKDLPPEDIMSLEASLLHLAL 520
           + Y T +       + T     + +F  F   +  +   R DL  +  + L  S++ L+L
Sbjct: 288 NDYVTRQLEDDPNATSTNAYLDMDVFGTFWDYLTVLNHERPDLSLQQFIPLVESVIVLSL 347

Query: 521 KVYPNKLELVDNVVKGATEALRNMNISKISYSS 619
           K YPN  + ++ + +   +  ++     IS  S
Sbjct: 348 KWYPNNFDNLNKLFELVLQKTKDYGQKNISLES 380
>sp|O74552|VPS35_SCHPO Vacuolar protein sorting-associated protein vps35
          Length = 785

 Score =  132 bits (333), Expect = 9e-31
 Identities = 88/309 (28%), Positives = 150/309 (48%), Gaps = 39/309 (12%)
 Frame = +2

Query: 2    FL*MNKLWVRMQHQGHTXXXXXXXXXXXXXXXXVGTNLNRLSQLESIDVERYKTTVLPAV 181
            F  MNKLWVR+QH G                  VG NL RLSQL ++D++ Y+  VLPA+
Sbjct: 137  FTEMNKLWVRIQHLGPIKEFSKRTQERNELKVLVGLNLVRLSQL-NLDIDTYRDHVLPAI 195

Query: 182  LEQIVNCHDAIAQEYLMDVVIQVFPDEFHLETLETLLRATSELEPNVHIKSIIGALIERL 361
            +EQI+ C D++AQEYL++V+ Q F D  HL+TL+T      +L P+V++  ++ A++ RL
Sbjct: 196  IEQIIECRDSLAQEYLVEVICQAFSDNMHLQTLDTYFGTVIKLSPSVNVTQLVVAMLNRL 255

Query: 362  SQY-----------------ATEESG-------------------TGIPDSIPLFDIFSR 433
            + Y                  TE+ G                     IP    + ++   
Sbjct: 256  TDYVQREYESDSSNEDESETVTEKLGDIKINEEVQQKDEQECPGDKVIPPEYAIQEVLWS 315

Query: 434  EVNSMVERRKDLPPEDIMSLEASLLHLALKVYPNKLELVDNVVKGATEALRNM-NISKIS 610
             V  +++ R  LP + I+S+ +S+L+  L+ YP K +  D V +   E + N  ++    
Sbjct: 316  HVVEVIQSRSGLPLDCIVSILSSILNFFLRCYPYKPQYADRVFQYINEHIINQPSLRSAL 375

Query: 611  YSSCLSRELIRLLKMPIDVYKDIRIILKLENYSDLIQNLEYNGRKLISCHLLTNTLDQNH 790
            +   L + L  +L +P+  +      L+L+N+  +    + N R  I+  ++   +++ H
Sbjct: 376  HERPLQKSLCAILLLPLTYFPSFSYCLELQNFLPVFNAQDPNLRYDIARMIVQKIIEKGH 435

Query: 791  VLN--TEEQ 811
             L+  TE Q
Sbjct: 436  SLSELTEAQ 444
>sp|Q58611|YC14_METJA Hypothetical protein MJ1214
          Length = 1018

 Score = 34.3 bits (77), Expect = 0.43
 Identities = 30/132 (22%), Positives = 62/132 (46%), Gaps = 1/132 (0%)
 Frame = +2

Query: 419  DIFSREVN-SMVERRKDLPPEDIMSLEASLLHLALKVYPNKLELVDNVVKGATEALRNMN 595
            DI S  +N  ++E  K+   ++I  + A +++ AL    NK E +  ++      L+N  
Sbjct: 846  DIASTSINPQLLENLKN--KDEINVIVADMIYYALDTLQNKKEPIYRMIYDRINELKNAY 903

Query: 596  ISKISYSSCLSRELIRLLKMPIDVYKDIRIILKLENYSDLIQNLEYNGRKLISCHLLTNT 775
            ISK   +  +  ELI  L       ++ + + K E     I+N+ +  + + +C++    
Sbjct: 904  ISKTKKNEYVINELINCLNALKTYEEEEKTLSKSEK---AIKNMLFYLKNVENCNIKKLP 960

Query: 776  LDQNHVLNTEEQ 811
            L +  + N E++
Sbjct: 961  LTEKTLKNLEDK 972
>sp|Q8TDY2|RBCC1_HUMAN RB1-inducible coiled-coil protein 1
          Length = 1594

 Score = 33.9 bits (76), Expect = 0.57
 Identities = 51/208 (24%), Positives = 88/208 (42%), Gaps = 16/208 (7%)
 Frame = +2

Query: 179  VLEQIVNCHDAIAQE---YLMDVVIQV---------FPDEFHLETLET----LLRATSEL 310
            ++ QI   H  I QE    L ++ ++V            E  L+  ET    +L   S  
Sbjct: 1024 IINQIQESHAEIIQEKEKQLQELKLKVSDLSDTRCKLEVELALKEAETDEIKILLEESRA 1083

Query: 311  EPNVHIKSIIGALIERLSQYATEESGTGIPDSIPLFDIFSREVNSMVERRKDLPPEDIMS 490
            +    +KS++    E L +    +    I D+   + +   E+ +++   KD    +++S
Sbjct: 1084 QQKETLKSLLEQETENL-RTEISKLNQKIQDNNENYQVGLAELRTLMTIEKDQCISELIS 1142

Query: 491  LEASLLHLALKVYPNKLELVDNVVKGATEALRNMNISKISYSSCLSRELIRLLKMPIDVY 670
                  ++ LK   NK+  + N    A E  +N+    I   S L  EL  L +      
Sbjct: 1143 RHEEESNI-LKAELNKVTSLHNQ---AFEIEKNLKEQIIELQSKLDSELSALERQ----- 1193

Query: 671  KDIRIILKLENYSDLIQNLEYNGRKLIS 754
            KD +I  + E Y  +IQNLE + +KL+S
Sbjct: 1194 KDEKITQQEEKYEAIIQNLEKDRQKLVS 1221
>sp|Q859W7|YCF2_ANTFO Protein ycf2
          Length = 2392

 Score = 32.3 bits (72), Expect = 1.7
 Identities = 16/63 (25%), Positives = 34/63 (53%)
 Frame = +3

Query: 351 LNDFLNMQLKKVEQEFLTVFLYSTYFQERLIQWWNAVKICPLKISCLLKHHYFIWH*KFI 530
           LN+  + +++   +E    ++Y T  +++L  W+   K   + +  ++K +Y I+  KF 
Sbjct: 779 LNEMFHKKVEAHSEENFETYIYPTNHRKKLKLWYELNKGSYICLDNVVKKYYSIYKLKFY 838

Query: 531 LIN 539
           LIN
Sbjct: 839 LIN 841
>sp|O60566|BUB1B_HUMAN Mitotic checkpoint serine/threonine-protein kinase BUB1 beta (hBUBR1)
            (MAD3/BUB1-related protein kinase) (Mitotic checkpoint
            kinase MAD3L) (SSK1)
          Length = 1050

 Score = 31.6 bits (70), Expect = 2.8
 Identities = 26/94 (27%), Positives = 48/94 (51%), Gaps = 1/94 (1%)
 Frame = +3

Query: 282  KLFYEPPQNWSQMYI*NL*LEH*LNDF-LNMQLKKVEQEFLTVFLYSTYFQERLIQWWNA 458
            KLF+  P+N +++ +  +  +    DF +N++LK+   E    F     +Q+  I W   
Sbjct: 779  KLFWVAPRNSAELTVIKVSSQPVPWDFYINLKLKERLNEDFDHFCSCYQYQDGCIVWHQY 838

Query: 459  VKICPLKISCLLKHHYFIWH*KFILINWNLSTML 560
            +    L+   LL+H  +I H   +LI +NL T++
Sbjct: 839  INCFTLQD--LLQHSEYITHEITVLIIYNLLTIV 870
>sp|Q61098|IL18R_MOUSE Interleukin-18 receptor 1 precursor (IL1 receptor-related protein)
           (IL-1Rrp)
          Length = 537

 Score = 30.8 bits (68), Expect = 4.8
 Identities = 20/71 (28%), Positives = 36/71 (50%), Gaps = 2/71 (2%)
 Frame = +2

Query: 518 LKVYPNKLELVDNVVKGATEALRN--MNISKISYSSCLSRELIRLLKMPIDVYKDIRIIL 691
           L+ +P ++E     +       RN  +N++K +  SC S +L+      ++V K + I  
Sbjct: 84  LEFWPVEMEDEGTYISQVGNDRRNWTLNVTKRNKHSCFSDKLVT--SRDVEVNKSLHITC 141

Query: 692 KLENYSDLIQN 724
           K  NY +LIQ+
Sbjct: 142 KNPNYEELIQD 152
>sp|Q8TMT1|DNLI_METAC DNA ligase (Polydeoxyribonucleotide synthase [ATP])
          Length = 568

 Score = 30.4 bits (67), Expect = 6.3
 Identities = 26/78 (33%), Positives = 37/78 (47%), Gaps = 6/78 (7%)
 Frame = +2

Query: 365 QYATEESGTGIPDSIPLFDIFSREVNS-----MVERRKDLPPEDIMSLEAS-LLHLALKV 526
           +Y  EE   GIP  + LFDI      +     +VERRK L      S+E S  + +  +V
Sbjct: 329 KYDVEEKALGIPIQLNLFDIMYLNGRTLIDLPLVERRKALESCVESSVEDSKSISVDEQV 388

Query: 527 YPNKLELVDNVVKGATEA 580
               LELV+ + + A  A
Sbjct: 389 ITGDLELVEKIYREALNA 406
  Database: Non-redundant SwissProt sequences
    Posted date:  Dec 6, 2005  7:40 AM
  Number of letters in database: 68,354,980
  Number of sequences in database:  184,735
  
  Database: swissprot.01
    Posted date:  Dec 6, 2005  8:18 AM
  Number of letters in database: 66,202,850
  Number of sequences in database:  184,431
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 86,937,718
Number of Sequences: 369166
Number of extensions: 1668804
Number of successful extensions: 4613
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 4483
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4604
length of database: 68,354,980
effective HSP length: 109
effective length of database: 48,218,865
effective search space used: 8100769320
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)