Planaria EST Database


DrC_01377

BLASTX 2.2.13 [Nov-27-2005]

Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= DrC_01377
         (909 letters)

Database: Non-redundant SwissProt sequences 
           184,735 sequences; 68,354,980 total letters



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

sp|Q9EQQ0|SUV92_MOUSE  Histone-lysine N-methyltransferase, H...   218   1e-56
sp|Q9H5I1|SUV92_HUMAN  Histone-lysine N-methyltransferase, H...   214   2e-55
sp|O43463|SUV91_HUMAN  Histone-lysine N-methyltransferase, H...   211   2e-54
sp|O54864|SUV91_MOUSE  Histone-lysine N-methyltransferase, H...   208   1e-53
sp|P45975|SUV9_DROME  Histone-lysine N-methyltransferase, H3...   177   3e-44
sp|O60016|CLR4_SCHPO  Histone-lysine N-methyltransferase, H3...   164   4e-40
sp|Q96KQ7|EHMT2_HUMAN  Histone-lysine N-methyltransferase, H...   148   2e-35
sp|Q9Z148|EHMT2_MOUSE  Histone-lysine N-methyltransferase, H...   146   9e-35
sp|Q9H9B1|EHMT1_HUMAN  Histone-lysine N-methyltransferase, H...   140   5e-33
sp|Q8VZ17|SUV6_ARATH  Histone-lysine N-methyltransferase, H3...   139   8e-33
>sp|Q9EQQ0|SUV92_MOUSE Histone-lysine N-methyltransferase, H3 lysine-9 specific 2 (Histone
           H3-K9 methyltransferase 2) (H3-K9-HMTase 2) (Suppressor
           of variegation 3-9 homolog 2) (Su(var)3-9 homolog 2)
          Length = 477

 Score =  218 bits (556), Expect = 1e-56
 Identities = 120/271 (44%), Positives = 158/271 (58%), Gaps = 2/271 (0%)
 Frame = +3

Query: 3   GPPLDFQFITDY-VSNGIEIHSNPPIGCHCETSCLENKKDCSFIHGGDPPYTITGKVIPR 179
           GPPLDF +I +Y  + GI I+S    GC C T C  +K  C    G    Y    ++  +
Sbjct: 231 GPPLDFYYINEYRPAPGISINSEATFGCSC-TDCFFDKC-CPAEAGVVLAYNKKQQIKIQ 288

Query: 180 VGVPVYECNSACTCDINCRYRVVQRGVKLQLKIFRTVNR-GWGLKTLTKIVKGNFIMEYL 356
            G P+YECNS C C   C  R+VQ+G +  L IF+T N  GWG+KTL KI + +F+MEY+
Sbjct: 289 PGTPIYECNSRCRCGPECPNRIVQKGTQYSLCIFKTSNGCGWGVKTLVKIKRMSFVMEYV 348

Query: 357 GEIVTVDEAEERGKLYDQQNLTYLFDLDFAGDPEFTVDAYKKGNMSHFINHSCNPNMTSR 536
           GE++T +EAE RG+ YD + +TYLFDLD+  D EFTVDA + GN+SHF+NHSC+PN+   
Sbjct: 349 GEVITSEEAERRGQFYDNKGITYLFDLDYESD-EFTVDAARYGNVSHFVNHSCDPNLQVF 407

Query: 537 CVFINNLDIRMPRIAFYADRDIRSGEELTFDYMMTGAMSGNKENEGXXXXXXXXXINVNT 716
            VFI+NLD R+PRIA ++ R I +GEELTFDY M G  SG   ++          +    
Sbjct: 408 SVFIDNLDTRLPRIALFSTRTINAGEELTFDYQMKG--SGEASSDSIDHSPAKKRV---- 461

Query: 717 KYXXXXXXXXXXQVTGRVPCLCDAANCRKYL 809
                           R  C C A  CR YL
Sbjct: 462 ----------------RTQCKCGAETCRGYL 476
>sp|Q9H5I1|SUV92_HUMAN Histone-lysine N-methyltransferase, H3 lysine-9 specific 2 (Histone
           H3-K9 methyltransferase 2) (H3-K9-HMTase 2) (Suppressor
           of variegation 3-9 homolog 2) (Su(var)3-9 homolog 2)
          Length = 410

 Score =  214 bits (546), Expect = 2e-55
 Identities = 119/271 (43%), Positives = 158/271 (58%), Gaps = 2/271 (0%)
 Frame = +3

Query: 3   GPPLDFQFITDYV-SNGIEIHSNPPIGCHCETSCLENKKDCSFIHGGDPPYTITGKVIPR 179
           GPP DF +I +Y  + GI + +    GC C T C   +K C    G    Y    ++   
Sbjct: 164 GPPSDFYYINEYKPAPGISLVNEATFGCSC-TDCFF-QKCCPAEAGVLLAYNKNQQIKIP 221

Query: 180 VGVPVYECNSACTCDINCRYRVVQRGVKLQLKIFRTVN-RGWGLKTLTKIVKGNFIMEYL 356
            G P+YECNS C C  +C  R+VQ+G +  L IFRT N RGWG+KTL KI + +F+MEY+
Sbjct: 222 PGTPIYECNSRCQCGPDCPNRIVQKGTQYSLCIFRTSNGRGWGVKTLVKIKRMSFVMEYV 281

Query: 357 GEIVTVDEAEERGKLYDQQNLTYLFDLDFAGDPEFTVDAYKKGNMSHFINHSCNPNMTSR 536
           GE++T +EAE RG+ YD + +TYLFDLD+  D EFTVDA + GN+SHF+NHSC+PN+   
Sbjct: 282 GEVITSEEAERRGQFYDNKGITYLFDLDYESD-EFTVDAARYGNVSHFVNHSCDPNLQVF 340

Query: 537 CVFINNLDIRMPRIAFYADRDIRSGEELTFDYMMTGAMSGNKENEGXXXXXXXXXINVNT 716
            VFI+NLD R+PRIA ++ R I +GEELTFDY M G  SG+  ++          +    
Sbjct: 341 NVFIDNLDTRLPRIALFSTRTINAGEELTFDYQMKG--SGDISSDSIDHSPAKKRV---- 394

Query: 717 KYXXXXXXXXXXQVTGRVPCLCDAANCRKYL 809
                           R  C C A  CR YL
Sbjct: 395 ----------------RTVCKCGAVTCRGYL 409
>sp|O43463|SUV91_HUMAN Histone-lysine N-methyltransferase, H3 lysine-9 specific 1 (Histone
           H3-K9 methyltransferase 1) (H3-K9-HMTase 1) (Suppressor
           of variegation 3-9 homolog 1) (Su(var)3-9 homolog 1)
          Length = 412

 Score =  211 bits (538), Expect = 2e-54
 Identities = 124/280 (44%), Positives = 165/280 (58%), Gaps = 11/280 (3%)
 Frame = +3

Query: 3   GPPLDFQFITDY-VSNGIEIHSNPPIGCHCETSCLENKKDCSFIH-GGDPP--------Y 152
           GPP  F +I +Y V  GI ++    +GC C+        DC +   GG  P        Y
Sbjct: 155 GPPRAFVYINEYRVGEGITLNQ-VAVGCECQ--------DCLWAPTGGCCPGASLHKFAY 205

Query: 153 TITGKVIPRVGVPVYECNSACTCDINCRYRVVQRGVKLQLKIFRTVN-RGWGLKTLTKIV 329
              G+V  R G+P+YECNS C C  +C  RVVQ+G++  L IFRT + RGWG++TL KI 
Sbjct: 206 NDQGQVRLRAGLPIYECNSRCRCGYDCPNRVVQKGIRYDLCIFRTDDGRGWGVRTLEKIR 265

Query: 330 KGNFIMEYLGEIVTVDEAEERGKLYDQQNLTYLFDLDFAGDPEFTVDAYKKGNMSHFINH 509
           K +F+MEY+GEI+T +EAE RG++YD+Q  TYLFDLD+  D  +TVDA   GN+SHF+NH
Sbjct: 266 KNSFVMEYVGEIITSEEAERRGQIYDRQGATYLFDLDYVEDV-YTVDAAYYGNISHFVNH 324

Query: 510 SCNPNMTSRCVFINNLDIRMPRIAFYADRDIRSGEELTFDYMMTGAMSGNKENEGXXXXX 689
           SC+PN+    VFI+NLD R+PRIAF+A R IR+GEELTFDY M      + E+       
Sbjct: 325 SCDPNLQVYNVFIDNLDERLPRIAFFATRTIRAGEELTFDYNMQ-VDPVDMESTRMDSNF 383

Query: 690 XXXXINVNTKYXXXXXXXXXXQVTGRVPCLCDAANCRKYL 809
               +  + K               R+ C C   +CRKYL
Sbjct: 384 GLAGLPGSPKKRV------------RIECKCGTESCRKYL 411
>sp|O54864|SUV91_MOUSE Histone-lysine N-methyltransferase, H3 lysine-9 specific 1 (Histone
           H3-K9 methyltransferase 1) (H3-K9-HMTase 1) (Suppressor
           of variegation 3-9 homolog 1) (Su(var)3-9 homolog 1)
           (Position-effect variegation 3-9 homolog)
          Length = 412

 Score =  208 bits (530), Expect = 1e-53
 Identities = 110/217 (50%), Positives = 146/217 (67%), Gaps = 5/217 (2%)
 Frame = +3

Query: 3   GPPLDFQFITDY-VSNGIEIHSNPPIGCHCETSCLENKKDC---SFIHGGDPPYTITGKV 170
           GPP  F +I +Y V  GI ++    +GC C+   L     C   + +H     Y   G+V
Sbjct: 155 GPPRSFVYINEYRVGEGITLNQ-VAVGCECQDCLLAPTGGCCPGASLHKF--AYNDQGQV 211

Query: 171 IPRVGVPVYECNSACTCDINCRYRVVQRGVKLQLKIFRTVN-RGWGLKTLTKIVKGNFIM 347
             + G P+YECNS C C  +C  RVVQ+G++  L IFRT + RGWG++TL KI K +F+M
Sbjct: 212 RLKAGQPIYECNSRCCCGYDCPNRVVQKGIRYDLCIFRTNDGRGWGVRTLEKIRKNSFVM 271

Query: 348 EYLGEIVTVDEAEERGKLYDQQNLTYLFDLDFAGDPEFTVDAYKKGNMSHFINHSCNPNM 527
           EY+GEI+T +EAE RG++YD+Q  TYLFDLD+  D  +TVDA   GN+SHF+NHSC+PN+
Sbjct: 272 EYVGEIITSEEAERRGQIYDRQGATYLFDLDYVEDV-YTVDAAYYGNISHFVNHSCDPNL 330

Query: 528 TSRCVFINNLDIRMPRIAFYADRDIRSGEELTFDYMM 638
               VFI+NLD R+PRIAF+A R I +GEELTFDY M
Sbjct: 331 QVYNVFIDNLDERLPRIAFFATRTIWAGEELTFDYNM 367
>sp|P45975|SUV9_DROME Histone-lysine N-methyltransferase, H3 lysine-9 specific (Histone
            H3-K9 methyltransferase) (H3-K9-HMTase) (Suppressor of
            variegation protein 3-9)
          Length = 635

 Score =  177 bits (450), Expect = 3e-44
 Identities = 101/252 (40%), Positives = 140/252 (55%), Gaps = 7/252 (2%)
 Frame = +3

Query: 75   IGCHCETS---CLENKKDCSFIHGGDPPYT-ITGKVIPRVGVPVYECNSACTCDINCRYR 242
            +GC C      C  + K C+   G    Y   T ++  R G  +YECNS C+CD +C  R
Sbjct: 410  VGCKCTEDTEECTASTKCCARFAGELFAYERSTRRLRLRPGSAIYECNSRCSCDSSCSNR 469

Query: 243  VVQRGVKLQLKIFRTVN-RGWGLKTLTKIVKGNFIMEYLGEIVTVDEAEERGKLYDQQNL 419
            +VQ G ++ L +F+T N  GWG++  T + KG F+ EY+GEI+T DEA ERGK YD    
Sbjct: 470  LVQHGRQVPLVLFKTANGSGWGVRAATALRKGEFVCEYIGEIITSDEANERGKAYDDNGR 529

Query: 420  TYLFDLDF--AGDPEFTVDAYKKGNMSHFINHSCNPNMTSRCVFINNLDIRMPRIAFYAD 593
            TYLFDLD+  A D E+T+DA   GN+SHFINHSC+PN+     +I +L++ +P + F+  
Sbjct: 530  TYLFDLDYNTAQDSEYTIDAANYGNISHFINHSCDPNLAVFPCWIEHLNVALPHLVFFTL 589

Query: 594  RDIRSGEELTFDYMMTGAMSGNKENEGXXXXXXXXXINVNTKYXXXXXXXXXXQVTGRVP 773
            R I++GEEL+FDY+         +NE           N++T                RV 
Sbjct: 590  RPIKAGEELSFDYI-------RADNEDVPYE------NLSTAV--------------RVE 622

Query: 774  CLCDAANCRKYL 809
            C C   NCRK L
Sbjct: 623  CRCGRDNCRKVL 634
>sp|O60016|CLR4_SCHPO Histone-lysine N-methyltransferase, H3 lysine-9 specific (Histone
           H3-K9 methyltransferase) (H3-K9-HMTase) (Cryptic loci
           regulator 4)
          Length = 490

 Score =  164 bits (414), Expect = 4e-40
 Identities = 95/219 (43%), Positives = 125/219 (57%), Gaps = 10/219 (4%)
 Frame = +3

Query: 6   PPLDFQFITDYVSNGIEIHSNPPI--GCHCET--SC-LENKKDCSFIHGGDPP----YTI 158
           P LDFQFI+ Y      I  +P    GC+C +   C L N   C  +   D P    Y  
Sbjct: 233 PSLDFQFISQYRLTQGVIPPDPNFQSGCNCSSLGGCDLNNPSRCECLDDLDEPTHFAYDA 292

Query: 159 TGKVIPRVGVPVYECNSACTCDINCRYRVVQRGVKLQLKIFRTVNRGWGLKTLTKIVKGN 338
            G+V    G  +YECNS C+C + C  RVVQRG  L L+IF+T  +GWG+++L     G 
Sbjct: 293 QGRVRADTGAVIYECNSFCSCSMECPNRVVQRGRTLPLEIFKTKEKGWGVRSLRFAPAGT 352

Query: 339 FIMEYLGEIVTVDEAEERGKLYDQQNLTYLFDLDFAGD-PEFTVDAYKKGNMSHFINHSC 515
           FI  YLGE++T  EA +R K YD   +TYLFDLD   D  E+TVDA   G++S F NHSC
Sbjct: 353 FITCYLGEVITSAEAAKRDKNYDDDGITYLFDLDMFDDASEYTVDAQNYGDVSRFFNHSC 412

Query: 516 NPNMTSRCVFINNLDIRMPRIAFYADRDIRSGEELTFDY 632
           +PN+       N+    +  +AF+A +DI+  EELTFDY
Sbjct: 413 SPNIAIYSAVRNHGFRTIYDLAFFAIKDIQPLEELTFDY 451
>sp|Q96KQ7|EHMT2_HUMAN Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (Histone
            H3-K9 methyltransferase 3) (H3-K9-HMTase 3) (Euchromatic
            histone-lysine N-methyltransferase 2) (HLA-B associated
            transcript 8) (G9a protein)
          Length = 1210

 Score =  148 bits (373), Expect = 2e-35
 Identities = 70/147 (47%), Positives = 102/147 (69%)
 Frame = +3

Query: 192  VYECNSACTCDINCRYRVVQRGVKLQLKIFRTVNRGWGLKTLTKIVKGNFIMEYLGEIVT 371
            ++ECN AC+C  NC+ RVVQ G+K++L+++RT   GWG++ L  I +G FI EY+GE+++
Sbjct: 1014 IFECNQACSCWRNCKNRVVQSGIKVRLQLYRTAKMGWGVRALQTIPQGTFICEYVGELIS 1073

Query: 372  VDEAEERGKLYDQQNLTYLFDLDFAGDPEFTVDAYKKGNMSHFINHSCNPNMTSRCVFIN 551
              EA+ R      ++ +YLFDLD      + +DA   GN+S FINH C+PN+    VF+ 
Sbjct: 1074 DAEADVR------EDDSYLFDLDNKDGEVYCIDARYYGNISRFINHLCDPNIIPVRVFML 1127

Query: 552  NLDIRMPRIAFYADRDIRSGEELTFDY 632
            + D+R PRIAF++ RDIR+GEEL FDY
Sbjct: 1128 HQDLRFPRIAFFSSRDIRTGEELGFDY 1154
>sp|Q9Z148|EHMT2_MOUSE Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (Histone
            H3-K9 methyltransferase 3) (H3-K9-HMTase 3) (Euchromatic
            histone-lysine N-methyltransferase 2) (HLA-B associated
            transcript 8) (G9a protein)
          Length = 1263

 Score =  146 bits (368), Expect = 9e-35
 Identities = 69/147 (46%), Positives = 102/147 (69%)
 Frame = +3

Query: 192  VYECNSACTCDINCRYRVVQRGVKLQLKIFRTVNRGWGLKTLTKIVKGNFIMEYLGEIVT 371
            ++ECN AC+C  +C+ RVVQ G+K++L+++RT   GWG++ L  I +G FI EY+GE+++
Sbjct: 1067 IFECNQACSCWRSCKNRVVQSGIKVRLQLYRTAKMGWGVRALQTIPQGTFICEYVGELIS 1126

Query: 372  VDEAEERGKLYDQQNLTYLFDLDFAGDPEFTVDAYKKGNMSHFINHSCNPNMTSRCVFIN 551
              EA+ R      ++ +YLFDLD      + +DA   GN+S FINH C+PN+    VF+ 
Sbjct: 1127 DAEADVR------EDDSYLFDLDNKDGEVYCIDARYYGNISRFINHLCDPNIIPVRVFML 1180

Query: 552  NLDIRMPRIAFYADRDIRSGEELTFDY 632
            + D+R PRIAF++ RDIR+GEEL FDY
Sbjct: 1181 HQDLRFPRIAFFSSRDIRTGEELGFDY 1207
>sp|Q9H9B1|EHMT1_HUMAN Histone-lysine N-methyltransferase, H3 lysine-9 specific 5 (Histone
            H3-K9 methyltransferase 5) (H3-K9-HMTase 5) (Euchromatic
            histone-lysine N-methyltransferase 1) (Eu-HMTase1)
            (G9a-like protein 1) (GLP1)
          Length = 1267

 Score =  140 bits (353), Expect = 5e-33
 Identities = 69/165 (41%), Positives = 105/165 (63%), Gaps = 4/165 (2%)
 Frame = +3

Query: 150  YTITGKVIPRVGVP----VYECNSACTCDINCRYRVVQRGVKLQLKIFRTVNRGWGLKTL 317
            Y   G+++P   +     ++ECN AC+C  NCR RVVQ G++ +L+++RT + GWG+++L
Sbjct: 1053 YDKDGRLLPEFNMAEPPLIFECNHACSCWRNCRNRVVQNGLRARLQLYRTRDMGWGVRSL 1112

Query: 318  TKIVKGNFIMEYLGEIVTVDEAEERGKLYDQQNLTYLFDLDFAGDPEFTVDAYKKGNMSH 497
              I  G F+ EY+GE+++  EA+ R      +  +YLFDLD      + +DA   GN+S 
Sbjct: 1113 QDIPPGTFVCEYVGELISDSEADVR------EEDSYLFDLDNKDGEVYCIDARFYGNVSR 1166

Query: 498  FINHSCNPNMTSRCVFINNLDIRMPRIAFYADRDIRSGEELTFDY 632
            FINH C PN+    VF+ + D+R PRIAF++ R I +GE+L FDY
Sbjct: 1167 FINHHCEPNLVPVRVFMAHQDLRFPRIAFFSTRLIEAGEQLGFDY 1211
>sp|Q8VZ17|SUV6_ARATH Histone-lysine N-methyltransferase, H3 lysine-9 specific 6 (Histone
            H3-K9 methyltransferase 6) (H3-K9-HMTase 6) (Suppressor
            of variegation 3-9 homolog 6) (Su(var)3-9 homolog 6)
          Length = 790

 Score =  139 bits (351), Expect = 8e-33
 Identities = 90/271 (33%), Positives = 133/271 (49%), Gaps = 24/271 (8%)
 Frame = +3

Query: 69   PPIGCHCETSCLENK-KDCSFI--HGGDPPYTITGKVIPRVGVPVYECNSACTCDINCRY 239
            PP  C C T C E + + C+ +  +GG+ PY   G ++      +YEC   C C  +C  
Sbjct: 549  PPKSCCCTTRCTEAEARVCACVEKNGGEIPYNFDGAIVGAKPT-IYECGPLCKCPSSCYL 607

Query: 240  RVVQRGVKLQLKIFRTVNRGWGLKTLTKIVKGNFIMEYLGEIVTVDEAEER--------- 392
            RV Q G+KL L+IF+T +RGWG++ L  I  G+FI EY+GE++   EAE R         
Sbjct: 608  RVTQHGIKLPLEIFKTKSRGWGVRCLKSIPIGSFICEYVGELLEDSEAERRIGNDEYLFD 667

Query: 393  -GKLYDQQNLTYLFDLDFA---------GDPE--FTVDAYKKGNMSHFINHSCNPNMTSR 536
             G  YD      + +L            GD    FT+DA  KGN+  FINHSC+PN+ ++
Sbjct: 668  IGNRYDNSLAQGMSELMLGTQAGRSMAEGDESSGFTIDAASKGNVGRFINHSCSPNLYAQ 727

Query: 537  CVFINNLDIRMPRIAFYADRDIRSGEELTFDYMMTGAMSGNKENEGXXXXXXXXXINVNT 716
             V  ++ D R+P + F+A  +I   +EL +DY    A+   ++++G          N+  
Sbjct: 728  NVLYDHEDSRIPHVMFFAQDNIPPLQELCYDY--NYALDQVRDSKG----------NIKQ 775

Query: 717  KYXXXXXXXXXXQVTGRVPCLCDAANCRKYL 809
            K                 PC C AA CR+ L
Sbjct: 776  K-----------------PCFCGAAVCRRRL 789
  Database: Non-redundant SwissProt sequences
    Posted date:  Dec 6, 2005  7:40 AM
  Number of letters in database: 68,354,980
  Number of sequences in database:  184,735
  
  Database: swissprot.01
    Posted date:  Dec 6, 2005  8:18 AM
  Number of letters in database: 66,202,850
  Number of sequences in database:  184,431
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 92,925,832
Number of Sequences: 369166
Number of extensions: 1793618
Number of successful extensions: 4390
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 4143
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4286
length of database: 68,354,980
effective HSP length: 110
effective length of database: 48,034,130
effective search space used: 9222552960
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)