Planaria EST Database


DrC_01369

BLASTX 2.2.13 [Nov-27-2005]

Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= DrC_01369
         (789 letters)

Database: Non-redundant SwissProt sequences 
           184,735 sequences; 68,354,980 total letters



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

sp|O00410|IMB3_HUMAN  Importin beta-3 (Karyopherin beta-3) (...   174   2e-43
sp|O60518|RNBP6_HUMAN  Ran-binding protein 6 (RanBP6)             174   2e-43
sp|Q8BIV3|RNBP6_MOUSE  Ran-binding protein 6 (RanBP6)             173   4e-43
sp|Q8BKC5|IMB3_MOUSE  Importin beta-3 (Karyopherin beta-3) (...   171   2e-42
sp|O74476|IMB3_SCHPO  Importin beta-3 subunit                     119   1e-26
sp|P32337|IMB3_YEAST  Importin beta-3 subunit (Karyopherin b...    69   1e-11
sp|Q8VI75|IPO4_MOUSE  Importin-4 (Importin 4a) (Imp4a) (Ran-...    52   1e-06
sp|Q8TEX9|IPO4_HUMAN  Importin-4 (Importin 4b) (Imp4b) (Ran-...    45   2e-04
sp|O60100|IMB4_SCHPO  Probable importin beta-4 subunit (Kary...    44   7e-04
sp|Q86VP6|CAND1_HUMAN  Cullin-associated NEDD8-dissociated p...    35   0.31 
>sp|O00410|IMB3_HUMAN Importin beta-3 (Karyopherin beta-3) (Ran-binding protein 5) (RanBP5)
          Length = 1097

 Score =  174 bits (442), Expect = 2e-43
 Identities = 82/233 (35%), Positives = 144/233 (61%)
 Frame = +1

Query: 10   VIKLIDPSRPWSDLQYGLCFLDDLLEFTGHDSWQHCCTLLPVFRSAIEHPIPEVRQAAAY 189
            ++ LI P RPW D Q+GLC  DD++E     S+++    L      +    PEVRQAAAY
Sbjct: 868  IVNLICPHRPWPDRQWGLCIFDDVIEHCSPASFKYAEYFLRPMLQYVCDNSPEVRQAAAY 927

Query: 190  GFGLMAIHGGPQYQQFLSEVSEIMMRIMSNKNCRDVDNNLSTENVISALTKICKYQPNCI 369
            G G+MA +GG  Y+ F +E   +++R++ + + +  +N  +TEN ISA+ KI K++P+C+
Sbjct: 928  GLGVMAQYGGDNYRPFCTEALPLLVRVIQSADSKTKENVNATENCISAVGKIMKFKPDCV 987

Query: 370  LGGDVNRFLEVWLTWLPVYEDEEETPYVYGYLCELLENNNPVIIGSDNSNLGRVVKAIAT 549
               +V   L  WL+WLP++ED+EE    + YLC+L+E+N+P+++G +N+NL ++   IA 
Sbjct: 988  ---NVEEVLPHWLSWLPLHEDKEEAVQTFNYLCDLIESNHPIVLGPNNTNLPKIFSIIAE 1044

Query: 550  CITKEALPVDNEVYRRCLGIIRMIQTNEQFFNQCVQNLSDDEKMSLIRALDRA 708
                EA+  ++   +R   ++R +QT+   + +C+  LS +++ ++   L+ A
Sbjct: 1045 GEMHEAIKHEDPCAKRLANVVRQVQTSGGLWTECIAQLSPEQQAAIQELLNSA 1097
>sp|O60518|RNBP6_HUMAN Ran-binding protein 6 (RanBP6)
          Length = 1105

 Score =  174 bits (442), Expect = 2e-43
 Identities = 86/233 (36%), Positives = 141/233 (60%)
 Frame = +1

Query: 10   VIKLIDPSRPWSDLQYGLCFLDDLLEFTGHDSWQHCCTLLPVFRSAIEHPIPEVRQAAAY 189
            ++ LI  SRPW D Q+GLC  DD++E     S+++           +    PEVRQAAAY
Sbjct: 876  IVNLICSSRPWPDRQWGLCIFDDIIEHCSPTSFKYVEYFRWPMLLNMRDNNPEVRQAAAY 935

Query: 190  GFGLMAIHGGPQYQQFLSEVSEIMMRIMSNKNCRDVDNNLSTENVISALTKICKYQPNCI 369
            G G+MA  GG  Y+   SE   ++++++   N +   N ++TEN ISA+ KI K++PNC+
Sbjct: 936  GLGVMAQFGGDDYRSLCSEAVPLLVKVIKCANSKTKKNVIATENCISAIGKILKFKPNCV 995

Query: 370  LGGDVNRFLEVWLTWLPVYEDEEETPYVYGYLCELLENNNPVIIGSDNSNLGRVVKAIAT 549
               +V+  L  WL+WLP++ED+EE      +LC+L+E+N+PV+IG +NSNL +++  IA 
Sbjct: 996  ---NVDEVLPHWLSWLPLHEDKEEAIQTLSFLCDLIESNHPVVIGPNNSNLPKIISIIAE 1052

Query: 550  CITKEALPVDNEVYRRCLGIIRMIQTNEQFFNQCVQNLSDDEKMSLIRALDRA 708
                E +  ++   +R   ++R +QT+E  + +CV  L D+++ +L   L+ A
Sbjct: 1053 GKINETINYEDPCAKRLANVVRQVQTSEDLWLECVSQLDDEQQEALQELLNFA 1105
>sp|Q8BIV3|RNBP6_MOUSE Ran-binding protein 6 (RanBP6)
          Length = 439

 Score =  173 bits (439), Expect = 4e-43
 Identities = 86/233 (36%), Positives = 140/233 (60%)
 Frame = +1

Query: 10  VIKLIDPSRPWSDLQYGLCFLDDLLEFTGHDSWQHCCTLLPVFRSAIEHPIPEVRQAAAY 189
           ++ LI  SRPW D Q+GLC  DD++E     S+++           +    PEVRQAAAY
Sbjct: 210 IVNLICSSRPWPDRQWGLCIFDDIIEHCSPTSFKYVEYFRWPMLLNMRDNNPEVRQAAAY 269

Query: 190 GFGLMAIHGGPQYQQFLSEVSEIMMRIMSNKNCRDVDNNLSTENVISALTKICKYQPNCI 369
           G G+MA  GG  Y+   SE   ++++++   N +   N ++TEN ISA+ KI K++PNC+
Sbjct: 270 GLGVMAQFGGDDYRSLCSEAVPLLVKVIKCANSKTKKNVIATENCISAIGKILKFKPNCV 329

Query: 370 LGGDVNRFLEVWLTWLPVYEDEEETPYVYGYLCELLENNNPVIIGSDNSNLGRVVKAIAT 549
              +V+  L  WL+WLP++ED+EE      +LC+L+E+N+PV+IG +NSNL +++  IA 
Sbjct: 330 ---NVDEVLPHWLSWLPLHEDKEEAIQTLNFLCDLIESNHPVVIGPNNSNLPKIISIIAE 386

Query: 550 CITKEALPVDNEVYRRCLGIIRMIQTNEQFFNQCVQNLSDDEKMSLIRALDRA 708
               E +  ++   +R   ++R IQT+E+ + +C   L D+++ +L   L  A
Sbjct: 387 GKINETISHEDPCAKRLANVVRQIQTSEELWLECTSQLDDEQQEALHELLSFA 439
>sp|Q8BKC5|IMB3_MOUSE Importin beta-3 (Karyopherin beta-3) (Ran-binding protein 5) (RanBP5)
          Length = 1097

 Score =  171 bits (433), Expect = 2e-42
 Identities = 80/233 (34%), Positives = 141/233 (60%)
 Frame = +1

Query: 10   VIKLIDPSRPWSDLQYGLCFLDDLLEFTGHDSWQHCCTLLPVFRSAIEHPIPEVRQAAAY 189
            ++ LI P RPW D Q+GLC  DD++E     S+++    +      +    PEVRQAAAY
Sbjct: 868  IVNLICPQRPWPDRQWGLCIFDDIVEHCSPASFKYAEYFISPMLQYVCDNSPEVRQAAAY 927

Query: 190  GFGLMAIHGGPQYQQFLSEVSEIMMRIMSNKNCRDVDNNLSTENVISALTKICKYQPNCI 369
            G G+MA  GG  Y+ F ++   +++R++     +  +N  +TEN ISA+ KI K++P+C+
Sbjct: 928  GLGVMAQFGGDNYRPFCTDALPLLVRVIQAPEAKTKENVNATENCISAVGKIMKFKPDCV 987

Query: 370  LGGDVNRFLEVWLTWLPVYEDEEETPYVYGYLCELLENNNPVIIGSDNSNLGRVVKAIAT 549
               +V   L  WL+WLP++ED+EE    + YLC+L+E+N+P+++G +N+NL ++   IA 
Sbjct: 988  ---NVEEVLPHWLSWLPLHEDKEEAVQTFSYLCDLIESNHPIVLGPNNTNLPKIFSIIAE 1044

Query: 550  CITKEALPVDNEVYRRCLGIIRMIQTNEQFFNQCVQNLSDDEKMSLIRALDRA 708
                EA+  ++   +R   ++R +QT+   + +C+  LS +++ ++   L+ A
Sbjct: 1045 GEMHEAIKHEDPCAKRLANVVRQVQTSGGLWTECIAQLSPEQQAAIQELLNSA 1097
>sp|O74476|IMB3_SCHPO Importin beta-3 subunit
          Length = 1095

 Score =  119 bits (297), Expect = 1e-26
 Identities = 55/149 (36%), Positives = 87/149 (58%)
 Frame = +1

Query: 52   QYGLCFLDDLLEFTGHDSWQHCCTLLPVFRSAIEHPIPEVRQAAAYGFGLMAIHGGPQYQ 231
            Q+ LC +DDL+EFTG DSW +    LP     I+   PE+RQAA+YG G+ A HGG  Y 
Sbjct: 886  QWALCMMDDLIEFTGPDSWNYKDHFLPYLAEGIQSSEPEIRQAASYGIGVAAQHGGELYA 945

Query: 232  QFLSEVSEIMMRIMSNKNCRDVDNNLSTENVISALTKICKYQPNCILGGDVNRFLEVWLT 411
            +  S     + +++   + RD +   +TEN+  A+ KIC++    +   D+++ +  W+ 
Sbjct: 946  EICSSALPALFKMLELPDARDEEQIYATENICVAICKICRFCSQRV--QDLDKVVTYWIN 1003

Query: 412  WLPVYEDEEETPYVYGYLCELLENNNPVI 498
             LPV  DE++ PY Y +L EL+E N+  +
Sbjct: 1004 TLPVTHDEDDAPYAYTFLAELMEQNHVAV 1032
>sp|P32337|IMB3_YEAST Importin beta-3 subunit (Karyopherin beta-3 subunit) (Protein
            secretion enhancer 1)
          Length = 1089

 Score = 69.3 bits (168), Expect = 1e-11
 Identities = 43/173 (24%), Positives = 81/173 (46%), Gaps = 1/173 (0%)
 Frame = +1

Query: 55   YGLCFLDDLLEFTGHDSWQHCCTLLPVFRSAIEHPIPEVRQAAAYGFGLMAIHGGPQYQQ 234
            + L  + DL+++ G  +       +P     +  P   +RQAA+Y  G+ A +    Y  
Sbjct: 878  FALVVIGDLIQYGGEQTASMKNAFIPKVTECLISPDARIRQAASYIIGVCAQYAPSTYAD 937

Query: 235  FLSEVSEIMMRIMSNKNCRDVDNNLSTENVISALTKIC-KYQPNCILGGDVNRFLEVWLT 411
                  + +++I+     +  +N  STEN  +A+ KI   Y  N     +V+ +   W  
Sbjct: 938  VCIPTLDTLVQIVDFPGSKLEENRSSTENASAAIAKILYAYNSNI---PNVDTYTANWFK 994

Query: 412  WLPVYEDEEETPYVYGYLCELLENNNPVIIGSDNSNLGRVVKAIATCITKEAL 570
             LP   D+E   + Y +L +L+ENN+P++     SN+  VV ++   + + +L
Sbjct: 995  TLPTITDKEAASFNYQFLSQLIENNSPIVCA--QSNISAVVDSVIQALNERSL 1045
>sp|Q8VI75|IPO4_MOUSE Importin-4 (Importin 4a) (Imp4a) (Ran-binding protein 4) (RanBP4)
          Length = 1082

 Score = 52.4 bits (124), Expect = 1e-06
 Identities = 49/206 (23%), Positives = 89/206 (43%)
 Frame = +1

Query: 70   LDDLLEFTGHDSWQHCCTLLPVFRSAIEHPIPEVRQAAAYGFGLMAIHGGPQYQQFLSEV 249
            L + ++  G  S Q    L PV  +      PEVR  A +G G++A HGG   Q    ++
Sbjct: 883  LAESIQGLGTASAQFVSRLFPVLLNNAREADPEVRSNAIFGLGVLAEHGGCPAQDHFPKL 942

Query: 250  SEIMMRIMSNKNCRDVDNNLSTENVISALTKICKYQPNCILGGDVNRFLEVWLTWLPVYE 429
              +++ +++ +      ++   +N+  AL ++    P   +G    + L   L  LP+ E
Sbjct: 943  LGLLLPLLARER-----HDRVRDNICGALARVLMASP---VGKTEPQVLATLLRALPLKE 994

Query: 430  DEEETPYVYGYLCELLENNNPVIIGSDNSNLGRVVKAIATCITKEALPVDNEVYRRCLGI 609
            D EE     G+L   L  NNP  +    S L R+   I   +    +P D +     L +
Sbjct: 995  DMEEW-LTIGHLFSFLHQNNPEQVVDVASELLRICSLI---LPDNRIPPDTKAALLLL-L 1049

Query: 610  IRMIQTNEQFFNQCVQNLSDDEKMSL 687
              + + +   F+  + +L +D+   L
Sbjct: 1050 TFLAKQHTDSFHTALGSLPNDKAQEL 1075
>sp|Q8TEX9|IPO4_HUMAN Importin-4 (Importin 4b) (Imp4b) (Ran-binding protein 4) (RanBP4)
          Length = 1081

 Score = 45.1 bits (105), Expect = 2e-04
 Identities = 37/141 (26%), Positives = 64/141 (45%)
 Frame = +1

Query: 70   LDDLLEFTGHDSWQHCCTLLPVFRSAIEHPIPEVRQAAAYGFGLMAIHGGPQYQQFLSEV 249
            L + ++  G  S Q    LLPV  S  +   PEVR  A +G G++A HGG   Q+   ++
Sbjct: 882  LAETIQGLGAASAQFVSRLLPVLLSTAQEADPEVRSNAIFGMGVLAEHGGHPAQEHFPKL 941

Query: 250  SEIMMRIMSNKNCRDVDNNLSTENVISALTKICKYQPNCILGGDVNRFLEVWLTWLPVYE 429
              ++  +++ +      ++   +N+  AL ++    P         + L   L  LP+ E
Sbjct: 942  LGLLFPLLARER-----HDRVRDNICGALARLLMASPT---RKPEPQVLAALLHALPLKE 993

Query: 430  DEEETPYVYGYLCELLENNNP 492
            D EE   + G L   L  ++P
Sbjct: 994  DLEEWVTI-GRLFSFLYQSSP 1013
>sp|O60100|IMB4_SCHPO Probable importin beta-4 subunit (Karyopherin beta-4 subunit)
            (Importin 123)
          Length = 1067

 Score = 43.5 bits (101), Expect = 7e-04
 Identities = 34/163 (20%), Positives = 71/163 (43%)
 Frame = +1

Query: 133  VFRSAIEHPIPEVRQAAAYGFGLMAIHGGPQYQQFLSEVSEIMMRIMSNKNCRDVDNNLS 312
            +F +A+E    EVR  AAY  GL+              + + +    + +  R      +
Sbjct: 898  LFMAALEDSEGEVRSNAAYSMGLLCQFSTEDLSSEYLNILQKLQPFFTQEVFR-----TA 952

Query: 313  TENVISALTKICKYQPNCILGGDVNRFLEVWLTWLPVYEDEEETPYVYGYLCELLENNNP 492
             +N I  ++++  +  N I    V++ L +  + LP+ ED  E   +Y  +  L    NP
Sbjct: 953  LDNAIGCISRLILHNQNAI---PVDQVLPIVFSKLPLKEDYLENAPLYHMILALYRQQNP 1009

Query: 493  VIIGSDNSNLGRVVKAIATCITKEALPVDNEVYRRCLGIIRMI 621
             ++     +LG ++   A+ +T     +++E+    L +++ I
Sbjct: 1010 CLV----QHLGELIPVFASVLTGSPEQLNDELRSELLSMVKEI 1048
>sp|Q86VP6|CAND1_HUMAN Cullin-associated NEDD8-dissociated protein 1 (Cullin-associated and
            neddylation-dissociated protein 1) (p120 CAND1)
            (TBP-interacting protein TIP120A) (TBP-interacting
            protein of 120 kDa A)
          Length = 1230

 Score = 34.7 bits (78), Expect = 0.31
 Identities = 42/170 (24%), Positives = 72/170 (42%), Gaps = 9/170 (5%)
 Frame = +1

Query: 124  LLPVFRSAIEHPIPEVRQAAAYGFGLMAIHGGPQYQQFLSE--VSEIMMRIMSNKNCRDV 297
            L  V   A   P  EV+ AA+Y  G +++   P+Y  F+ +   S+   + +   + +++
Sbjct: 857  LKSVILEAFSSPSEEVKSAASYALGSISVGNLPEYLPFVLQEITSQPKRQYLLLHSLKEI 916

Query: 298  DNNLS-------TENVISALTKICKYQPNCILGGDVNRFLEVWLTWLPVYEDEEETPYVY 456
             ++ S        EN+ + L K C+    C   G  N   E  L  L + + E   P + 
Sbjct: 917  ISSASVVGLKPYVENIWALLLKHCE----CAEEGTRNVVAEC-LGKLTLIDPETLLPRLK 971

Query: 457  GYLCELLENNNPVIIGSDNSNLGRVVKAIATCITKEALPVDNEVYRRCLG 606
            GYL          I GS  +    VV A+   I+    P+D  + + C+G
Sbjct: 972  GYL----------ISGSSYAR-SSVVTAVKFTISDHPQPID-PLLKNCIG 1009
  Database: Non-redundant SwissProt sequences
    Posted date:  Dec 6, 2005  7:40 AM
  Number of letters in database: 68,354,980
  Number of sequences in database:  184,735
  
  Database: swissprot.01
    Posted date:  Dec 6, 2005  8:18 AM
  Number of letters in database: 66,202,850
  Number of sequences in database:  184,431
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 84,419,163
Number of Sequences: 369166
Number of extensions: 1659307
Number of successful extensions: 5857
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 5658
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5843
length of database: 68,354,980
effective HSP length: 108
effective length of database: 48,403,600
effective search space used: 7454154400
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)