Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= DrC_01311 (766 letters) Database: Non-redundant SwissProt sequences 184,735 sequences; 68,354,980 total letters Score E Sequences producing significant alignments: (bits) Value sp|Q9WUB0|UB7I3_MOUSE Ubiquitin-conjugating enzyme 7-intera... 69 1e-11 sp|Q62921|UB7I3_RAT Ubiquitin-conjugating enzyme 7-interact... 68 2e-11 sp|Q9BYM8|UB7I3_HUMAN Ubiquitin-conjugating enzyme 7-intera... 64 3e-10 sp|Q9UBS8|RNF14_HUMAN RING finger protein 14 (Androgen rece... 60 8e-09 sp|Q9JI90|RNF14_MOUSE RING finger protein 14 (Androgen rece... 60 8e-09 sp|O95376|ARI2_HUMAN Ariadne-2 protein homolog (ARI-2) (Tri... 52 2e-06 sp|Q9Y4X5|ARI1_HUMAN Ariadne-1 protein homolog (ARI-1) (Ubi... 51 4e-06 sp|Q9Z1K5|ARI1_MOUSE Ariadne-1 protein homolog (ARI-1) (Ubi... 51 4e-06 sp|P36113|YKZ7_YEAST Hypothetical 63.6 kDa protein in YPT52... 51 4e-06 sp|Q9Z1K6|ARI2_MOUSE Ariadne-2 protein homolog (ARI-2) (Tri... 50 5e-06
>sp|Q9WUB0|UB7I3_MOUSE Ubiquitin-conjugating enzyme 7-interacting protein 3 (UbcM4-interacting protein 28) Length = 498 Score = 68.9 bits (167), Expect = 1e-11 Identities = 41/146 (28%), Positives = 71/146 (48%), Gaps = 19/146 (13%) Frame = +1 Query: 43 EKCLLCNDEKDEC----------EKVKLK-CNHVFCWICFEKYLKINLSVTIKCPVV--- 180 ++ L+ N E EC E V L+ C H FC C + ++ + + CP + Sbjct: 258 QRSLVLNTEPTECPVCYSVLAPGEAVVLRECLHTFCRECLQGTIRNSQEAEVACPFIDST 317 Query: 181 -SCQEIIHDDQIRKVLCWEDLEKYENLCLK----DFTKAHYCLLPQCRIPVFYQDPNVQF 345 SC + + +IR +L ED +++ +L + T +++C P CR F++D +F Sbjct: 318 YSCPGKLLEREIRALLSPEDYQRFLDLGVSIAENRSTLSYHCKTPDCRGWCFFEDDVNEF 377 Query: 346 ECANCSLYNCIKCQAAHGFIGCKAYQ 423 C C+ NC+ C+A H + C+ YQ Sbjct: 378 TCPVCTRVNCLLCKAIHEHMNCREYQ 403
>sp|Q62921|UB7I3_RAT Ubiquitin-conjugating enzyme 7-interacting protein 3 (RBCC protein interacting with PKC) (Protein kinase C-binding protein beta-15) Length = 498 Score = 68.2 bits (165), Expect = 2e-11 Identities = 41/146 (28%), Positives = 71/146 (48%), Gaps = 19/146 (13%) Frame = +1 Query: 43 EKCLLCNDEKDEC----------EKVKLK-CNHVFCWICFEKYLKINLSVTIKCPVV--- 180 ++ L+ N E EC E V L+ C H FC C + ++ + + CP + Sbjct: 258 QRSLVLNTEPAECPVCYSVLAPGEAVVLRECLHTFCRECLQGTIRNSQEAEVSCPFIDNT 317 Query: 181 -SCQEIIHDDQIRKVLCWEDLEKYENLCLK----DFTKAHYCLLPQCRIPVFYQDPNVQF 345 SC + + +IR +L ED +++ +L + T +++C P CR F++D +F Sbjct: 318 YSCPGKLLEREIRALLSPEDYQRFLDLGVSIAENRSTLSYHCKTPDCRGWCFFEDDVNEF 377 Query: 346 ECANCSLYNCIKCQAAHGFIGCKAYQ 423 C C+ NC+ C+A H + C+ YQ Sbjct: 378 TCPVCTRVNCLLCKAIHERMNCREYQ 403
>sp|Q9BYM8|UB7I3_HUMAN Ubiquitin-conjugating enzyme 7-interacting protein 3 (Hepatitis B virus X-associated protein 4) (HBV-associated factor 4) (RING finger protein 54) Length = 500 Score = 64.3 bits (155), Expect = 3e-10 Identities = 39/146 (26%), Positives = 69/146 (47%), Gaps = 19/146 (13%) Frame = +1 Query: 43 EKCLLCNDEKDEC----------EKVKLK-CNHVFCWICFEKYLKINLSVTIKCPVV--- 180 ++ L+ N E EC E V L+ C H FC C + ++ + + CP + Sbjct: 260 QRSLVLNTEPAECPVCYSVLAPGEAVVLRECLHTFCRECLQGTIRNSQEAEVSCPFIDNT 319 Query: 181 -SCQEIIHDDQIRKVLCWEDLEKYENLCLKDFTK----AHYCLLPQCRIPVFYQDPNVQF 345 SC + + +I+ +L ED +++ +L + +++C P C+ F++D +F Sbjct: 320 YSCSGKLLEREIKALLTPEDYQRFLDLGISIAENRSAFSYHCKTPDCKGWCFFEDDVNEF 379 Query: 346 ECANCSLYNCIKCQAAHGFIGCKAYQ 423 C C NC+ C+A H + CK YQ Sbjct: 380 TCPVCFHVNCLLCKAIHEQMNCKEYQ 405
>sp|Q9UBS8|RNF14_HUMAN RING finger protein 14 (Androgen receptor-associated protein 54) (Triad2 protein) (HFB30) Length = 474 Score = 59.7 bits (143), Expect = 8e-09 Identities = 40/151 (26%), Positives = 66/151 (43%), Gaps = 11/151 (7%) Frame = +1 Query: 10 FSNQFFL*LNMEKCLLCNDEK--DECEKVKLKCNHVFCWICFEKYLKINLS----VTIKC 171 F+++ FL C +C EK EC L+C HV+C C + Y +I + + C Sbjct: 213 FNSKLFL------CSICFCEKLGSECMYF-LECRHVYCKACLKDYFEIQIRDGQVQCLNC 265 Query: 172 PVVSCQEIIHDDQIRKVLCWEDLEKYENLCLKD----FTKAHYCLLPQCRIPVFYQDPNV 339 P C + Q+++++ E +Y+ L L+ YC P C++PV + Sbjct: 266 PEPKCPSVATPGQVKELVEAELFARYDRLLLQSSLDLMADVVYCPRPCCQLPVMQEPGCT 325 Query: 340 QFECANCSLYNCIKCQAA-HGFIGCKAYQSK 429 C++C+ C C+ HG CK K Sbjct: 326 MGICSSCNFAFCTLCRLTYHGVSPCKVTAEK 356
>sp|Q9JI90|RNF14_MOUSE RING finger protein 14 (Androgen receptor-associated protein 54) (Triad2 protein) Length = 485 Score = 59.7 bits (143), Expect = 8e-09 Identities = 38/151 (25%), Positives = 66/151 (43%), Gaps = 11/151 (7%) Frame = +1 Query: 10 FSNQFFL*LNMEKCLLCNDEK--DECEKVKLKCNHVFCWICFEKYLKINLS----VTIKC 171 F+++ FL C +C EK +C L+C HV+C C + Y +I + + C Sbjct: 214 FNSKLFL------CSICFCEKLGSDCMYF-LECKHVYCKACLKDYFEIQIKDGQVKCLNC 266 Query: 172 PVVSCQEIIHDDQIRKVLCWEDLEKYENLCLKD----FTKAHYCLLPQCRIPVFYQDPNV 339 P C + Q+++++ + +Y+ L L+ YC P C++PV + Sbjct: 267 PEPQCPSVATPGQVKELVEADLFARYDRLLLQSTLDLMADVVYCPRPCCQLPVMQEPGGT 326 Query: 340 QFECANCSLYNCIKCQAA-HGFIGCKAYQSK 429 C++C+ C C+ HG CK K Sbjct: 327 MAICSSCNFAFCTLCRLTYHGLSPCKVTAEK 357
>sp|O95376|ARI2_HUMAN Ariadne-2 protein homolog (ARI-2) (Triad1 protein) Length = 493 Score = 51.6 bits (122), Expect = 2e-06 Identities = 32/123 (26%), Positives = 56/123 (45%), Gaps = 10/123 (8%) Frame = +1 Query: 49 CLLCNDEKDECEKVKLKCNHVFCWICFEKY----LKINLSVTIKCPVVSCQEIIHDDQIR 216 C +C + + L C H FC C+E++ +K + V + C C +D + Sbjct: 139 CAVCMQFVRKENLLSLACQHQFCRSCWEQHCSVLVKDGVGVGVSCMAQDCPLRTPEDFVF 198 Query: 217 KVLCWEDL-EKYENLCLKDFTKAHY----CLLPQCRIPVFYQDPNV-QFECANCSLYNCI 378 +L E+L EKY +D+ ++HY C C + + Q+P + +C C+ C Sbjct: 199 PLLPNEELREKYRRYLFRDYVESHYQLQLCPGADCPMVIRVQEPRARRVQCNRCNEVFCF 258 Query: 379 KCQ 387 KC+ Sbjct: 259 KCR 261
Score = 32.0 bits (71), Expect = 1.9 Identities = 11/28 (39%), Positives = 17/28 (60%), Gaps = 1/28 (3%) Frame = +1 Query: 46 KCLLCNDEKDECEKVKL-KCNHVFCWIC 126 KC +C ++ C ++ KC H FCW+C Sbjct: 299 KCNICIEKNGGCNHMQCSKCKHDFCWMC 326
>sp|Q9Y4X5|ARI1_HUMAN Ariadne-1 protein homolog (ARI-1) (Ubiquitin-conjugating enzyme E2-binding protein 1) (UbcH7-binding protein) (UbcM4-interacting protein) (HHARI) (H7-AP2) (MOP-6) Length = 557 Score = 50.8 bits (120), Expect = 4e-06 Identities = 36/154 (23%), Positives = 63/154 (40%), Gaps = 11/154 (7%) Frame = +1 Query: 49 CLLCNDEKDECEKVKLKCNHVFCWICFEKYL-----KINLSVTIKCPVVSCQEIIHDDQI 213 C +C L+C H FC C+ +YL + + TI CP C ++ D+ + Sbjct: 186 CQICYLNYPNSYFTGLECGHKFCMQCWSEYLTTKIMEEGMGQTISCPAHGCDILVDDNTV 245 Query: 214 RKVLCWEDLE-KYENLCLKDFTKAH----YCLLPQCRIPVFYQDPNVQFECANCSLYNCI 378 +++ ++ KY++L F + + +C P C V Q P+ + C C Sbjct: 246 MRLITDSKVKLKYQHLITNSFVECNRLLKWCPAPDCHHVVKVQYPDAKPVRCKCGRQFCF 305 Query: 379 KC-QAAHGFIGCKAYQSKPSKNKVKVCEGRDDIS 477 C + H + CK K +K C+ + S Sbjct: 306 NCGENWHDPVKCKWL-----KKWIKKCDDDSETS 334
>sp|Q9Z1K5|ARI1_MOUSE Ariadne-1 protein homolog (ARI-1) (Ubiquitin-conjugating enzyme E2-binding protein 1) (UbcH7-binding protein) (UbcM4-interacting protein 77) Length = 555 Score = 50.8 bits (120), Expect = 4e-06 Identities = 36/154 (23%), Positives = 63/154 (40%), Gaps = 11/154 (7%) Frame = +1 Query: 49 CLLCNDEKDECEKVKLKCNHVFCWICFEKYL-----KINLSVTIKCPVVSCQEIIHDDQI 213 C +C L+C H FC C+ +YL + + TI CP C ++ D+ + Sbjct: 184 CQICYLNYPNSYFTGLECGHKFCMQCWSEYLTTKIMEEGMGQTISCPAHGCDILVDDNTV 243 Query: 214 RKVLCWEDLE-KYENLCLKDFTKAH----YCLLPQCRIPVFYQDPNVQFECANCSLYNCI 378 +++ ++ KY++L F + + +C P C V Q P+ + C C Sbjct: 244 MRLITDSKVKLKYQHLITNSFVECNRLLKWCPAPDCHHVVKVQYPDAKPVRCKCGRQFCF 303 Query: 379 KC-QAAHGFIGCKAYQSKPSKNKVKVCEGRDDIS 477 C + H + CK K +K C+ + S Sbjct: 304 NCGENWHDPVKCKWL-----KKWIKKCDDDSETS 332
>sp|P36113|YKZ7_YEAST Hypothetical 63.6 kDa protein in YPT52-GCN3 intergenic region Length = 551 Score = 50.8 bits (120), Expect = 4e-06 Identities = 31/123 (25%), Positives = 52/123 (42%), Gaps = 5/123 (4%) Frame = +1 Query: 49 CLLCNDEKDECEKVKLKCNHVFCWICFEKYLKINLSVTIKCPVVSCQEIIHDDQIRKVLC 228 C++C D+KD E L+C H +C C+ Y+K L + C + ++ I KV+ Sbjct: 179 CIICCDKKDT-ETFALECGHEYCINCYRHYIKDKLHEGNIITCMDCSLALKNEDIDKVMG 237 Query: 229 WEDLEKYENLCLKDFTKAH-----YCLLPQCRIPVFYQDPNVQFECANCSLYNCIKCQAA 393 K + +K F + H +C C+ V +D + E +KC + Sbjct: 238 HPSSSKLMDSSIKSFVQKHNRNYKWCPFADCKSIVHLRDTSSLPEYTRLHYSPFVKCNSF 297 Query: 394 HGF 402 H F Sbjct: 298 HRF 300
>sp|Q9Z1K6|ARI2_MOUSE Ariadne-2 protein homolog (ARI-2) (Triad1 protein) (UbcM4-interacting protein 48) Length = 492 Score = 50.4 bits (119), Expect = 5e-06 Identities = 32/123 (26%), Positives = 56/123 (45%), Gaps = 10/123 (8%) Frame = +1 Query: 49 CLLCNDEKDECEKVKLKCNHVFCWICFEKY----LKINLSVTIKCPVVSCQEIIHDDQIR 216 C +C + + L C H FC C+E++ +K + V I C C +D + Sbjct: 138 CAVCMQFVRKENLLSLACQHQFCRSCWEQHCSVLVKDGVGVGISCMAQDCPLRTPEDFVF 197 Query: 217 KVLCWEDL-EKYENLCLKDFTKAHY----CLLPQCRIPVFYQDPNV-QFECANCSLYNCI 378 +L E+L +KY +D+ ++H+ C C + + Q+P + +C CS C Sbjct: 198 PLLPNEELRDKYRRYLFRDYVESHFQLQLCPGADCPMVIRVQEPRARRVQCNRCSEVFCF 257 Query: 379 KCQ 387 KC+ Sbjct: 258 KCR 260
Score = 32.0 bits (71), Expect = 1.9 Identities = 11/28 (39%), Positives = 17/28 (60%), Gaps = 1/28 (3%) Frame = +1 Query: 46 KCLLCNDEKDECEKVKL-KCNHVFCWIC 126 KC +C ++ C ++ KC H FCW+C Sbjct: 298 KCNICIEKNGGCNHMQCSKCKHDFCWMC 325
Database: Non-redundant SwissProt sequences Posted date: Dec 6, 2005 7:40 AM Number of letters in database: 68,354,980 Number of sequences in database: 184,735 Database: swissprot.01 Posted date: Dec 6, 2005 8:18 AM Number of letters in database: 66,202,850 Number of sequences in database: 184,431 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 79,633,163 Number of Sequences: 369166 Number of extensions: 1617193 Number of successful extensions: 4384 Number of sequences better than 10.0: 10 Number of HSP's better than 10.0 without gapping: 4087 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 4359 length of database: 68,354,980 effective HSP length: 108 effective length of database: 48,403,600 effective search space used: 7066925600 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)