Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_003_D21
(766 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q9WUB0|UB7I3_MOUSE Ubiquitin-conjugating enzyme 7-intera... 69 1e-11
sp|Q62921|UB7I3_RAT Ubiquitin-conjugating enzyme 7-interact... 68 2e-11
sp|Q9BYM8|UB7I3_HUMAN Ubiquitin-conjugating enzyme 7-intera... 64 3e-10
sp|Q9UBS8|RNF14_HUMAN RING finger protein 14 (Androgen rece... 60 8e-09
sp|Q9JI90|RNF14_MOUSE RING finger protein 14 (Androgen rece... 60 8e-09
sp|O95376|ARI2_HUMAN Ariadne-2 protein homolog (ARI-2) (Tri... 52 2e-06
sp|Q9Y4X5|ARI1_HUMAN Ariadne-1 protein homolog (ARI-1) (Ubi... 51 4e-06
sp|Q9Z1K5|ARI1_MOUSE Ariadne-1 protein homolog (ARI-1) (Ubi... 51 4e-06
sp|P36113|YKZ7_YEAST Hypothetical 63.6 kDa protein in YPT52... 51 4e-06
sp|Q9Z1K6|ARI2_MOUSE Ariadne-2 protein homolog (ARI-2) (Tri... 50 5e-06
>sp|Q9WUB0|UB7I3_MOUSE Ubiquitin-conjugating enzyme 7-interacting protein 3
(UbcM4-interacting protein 28)
Length = 498
Score = 68.9 bits (167), Expect = 1e-11
Identities = 41/146 (28%), Positives = 71/146 (48%), Gaps = 19/146 (13%)
Frame = +1
Query: 43 EKCLLCNDEKDEC----------EKVKLK-CNHVFCWICFEKYLKINLSVTIKCPVV--- 180
++ L+ N E EC E V L+ C H FC C + ++ + + CP +
Sbjct: 258 QRSLVLNTEPTECPVCYSVLAPGEAVVLRECLHTFCRECLQGTIRNSQEAEVACPFIDST 317
Query: 181 -SCQEIIHDDQIRKVLCWEDLEKYENLCLK----DFTKAHYCLLPQCRIPVFYQDPNVQF 345
SC + + +IR +L ED +++ +L + T +++C P CR F++D +F
Sbjct: 318 YSCPGKLLEREIRALLSPEDYQRFLDLGVSIAENRSTLSYHCKTPDCRGWCFFEDDVNEF 377
Query: 346 ECANCSLYNCIKCQAAHGFIGCKAYQ 423
C C+ NC+ C+A H + C+ YQ
Sbjct: 378 TCPVCTRVNCLLCKAIHEHMNCREYQ 403
>sp|Q62921|UB7I3_RAT Ubiquitin-conjugating enzyme 7-interacting protein 3 (RBCC protein
interacting with PKC) (Protein kinase C-binding protein
beta-15)
Length = 498
Score = 68.2 bits (165), Expect = 2e-11
Identities = 41/146 (28%), Positives = 71/146 (48%), Gaps = 19/146 (13%)
Frame = +1
Query: 43 EKCLLCNDEKDEC----------EKVKLK-CNHVFCWICFEKYLKINLSVTIKCPVV--- 180
++ L+ N E EC E V L+ C H FC C + ++ + + CP +
Sbjct: 258 QRSLVLNTEPAECPVCYSVLAPGEAVVLRECLHTFCRECLQGTIRNSQEAEVSCPFIDNT 317
Query: 181 -SCQEIIHDDQIRKVLCWEDLEKYENLCLK----DFTKAHYCLLPQCRIPVFYQDPNVQF 345
SC + + +IR +L ED +++ +L + T +++C P CR F++D +F
Sbjct: 318 YSCPGKLLEREIRALLSPEDYQRFLDLGVSIAENRSTLSYHCKTPDCRGWCFFEDDVNEF 377
Query: 346 ECANCSLYNCIKCQAAHGFIGCKAYQ 423
C C+ NC+ C+A H + C+ YQ
Sbjct: 378 TCPVCTRVNCLLCKAIHERMNCREYQ 403
>sp|Q9BYM8|UB7I3_HUMAN Ubiquitin-conjugating enzyme 7-interacting protein 3 (Hepatitis B
virus X-associated protein 4) (HBV-associated factor 4)
(RING finger protein 54)
Length = 500
Score = 64.3 bits (155), Expect = 3e-10
Identities = 39/146 (26%), Positives = 69/146 (47%), Gaps = 19/146 (13%)
Frame = +1
Query: 43 EKCLLCNDEKDEC----------EKVKLK-CNHVFCWICFEKYLKINLSVTIKCPVV--- 180
++ L+ N E EC E V L+ C H FC C + ++ + + CP +
Sbjct: 260 QRSLVLNTEPAECPVCYSVLAPGEAVVLRECLHTFCRECLQGTIRNSQEAEVSCPFIDNT 319
Query: 181 -SCQEIIHDDQIRKVLCWEDLEKYENLCLKDFTK----AHYCLLPQCRIPVFYQDPNVQF 345
SC + + +I+ +L ED +++ +L + +++C P C+ F++D +F
Sbjct: 320 YSCSGKLLEREIKALLTPEDYQRFLDLGISIAENRSAFSYHCKTPDCKGWCFFEDDVNEF 379
Query: 346 ECANCSLYNCIKCQAAHGFIGCKAYQ 423
C C NC+ C+A H + CK YQ
Sbjct: 380 TCPVCFHVNCLLCKAIHEQMNCKEYQ 405
>sp|Q9UBS8|RNF14_HUMAN RING finger protein 14 (Androgen receptor-associated protein 54)
(Triad2 protein) (HFB30)
Length = 474
Score = 59.7 bits (143), Expect = 8e-09
Identities = 40/151 (26%), Positives = 66/151 (43%), Gaps = 11/151 (7%)
Frame = +1
Query: 10 FSNQFFL*LNMEKCLLCNDEK--DECEKVKLKCNHVFCWICFEKYLKINLS----VTIKC 171
F+++ FL C +C EK EC L+C HV+C C + Y +I + + C
Sbjct: 213 FNSKLFL------CSICFCEKLGSECMYF-LECRHVYCKACLKDYFEIQIRDGQVQCLNC 265
Query: 172 PVVSCQEIIHDDQIRKVLCWEDLEKYENLCLKD----FTKAHYCLLPQCRIPVFYQDPNV 339
P C + Q+++++ E +Y+ L L+ YC P C++PV +
Sbjct: 266 PEPKCPSVATPGQVKELVEAELFARYDRLLLQSSLDLMADVVYCPRPCCQLPVMQEPGCT 325
Query: 340 QFECANCSLYNCIKCQAA-HGFIGCKAYQSK 429
C++C+ C C+ HG CK K
Sbjct: 326 MGICSSCNFAFCTLCRLTYHGVSPCKVTAEK 356
>sp|Q9JI90|RNF14_MOUSE RING finger protein 14 (Androgen receptor-associated protein 54)
(Triad2 protein)
Length = 485
Score = 59.7 bits (143), Expect = 8e-09
Identities = 38/151 (25%), Positives = 66/151 (43%), Gaps = 11/151 (7%)
Frame = +1
Query: 10 FSNQFFL*LNMEKCLLCNDEK--DECEKVKLKCNHVFCWICFEKYLKINLS----VTIKC 171
F+++ FL C +C EK +C L+C HV+C C + Y +I + + C
Sbjct: 214 FNSKLFL------CSICFCEKLGSDCMYF-LECKHVYCKACLKDYFEIQIKDGQVKCLNC 266
Query: 172 PVVSCQEIIHDDQIRKVLCWEDLEKYENLCLKD----FTKAHYCLLPQCRIPVFYQDPNV 339
P C + Q+++++ + +Y+ L L+ YC P C++PV +
Sbjct: 267 PEPQCPSVATPGQVKELVEADLFARYDRLLLQSTLDLMADVVYCPRPCCQLPVMQEPGGT 326
Query: 340 QFECANCSLYNCIKCQAA-HGFIGCKAYQSK 429
C++C+ C C+ HG CK K
Sbjct: 327 MAICSSCNFAFCTLCRLTYHGLSPCKVTAEK 357
>sp|O95376|ARI2_HUMAN Ariadne-2 protein homolog (ARI-2) (Triad1 protein)
Length = 493
Score = 51.6 bits (122), Expect = 2e-06
Identities = 32/123 (26%), Positives = 56/123 (45%), Gaps = 10/123 (8%)
Frame = +1
Query: 49 CLLCNDEKDECEKVKLKCNHVFCWICFEKY----LKINLSVTIKCPVVSCQEIIHDDQIR 216
C +C + + L C H FC C+E++ +K + V + C C +D +
Sbjct: 139 CAVCMQFVRKENLLSLACQHQFCRSCWEQHCSVLVKDGVGVGVSCMAQDCPLRTPEDFVF 198
Query: 217 KVLCWEDL-EKYENLCLKDFTKAHY----CLLPQCRIPVFYQDPNV-QFECANCSLYNCI 378
+L E+L EKY +D+ ++HY C C + + Q+P + +C C+ C
Sbjct: 199 PLLPNEELREKYRRYLFRDYVESHYQLQLCPGADCPMVIRVQEPRARRVQCNRCNEVFCF 258
Query: 379 KCQ 387
KC+
Sbjct: 259 KCR 261
Score = 32.0 bits (71), Expect = 1.9
Identities = 11/28 (39%), Positives = 17/28 (60%), Gaps = 1/28 (3%)
Frame = +1
Query: 46 KCLLCNDEKDECEKVKL-KCNHVFCWIC 126
KC +C ++ C ++ KC H FCW+C
Sbjct: 299 KCNICIEKNGGCNHMQCSKCKHDFCWMC 326
>sp|Q9Y4X5|ARI1_HUMAN Ariadne-1 protein homolog (ARI-1) (Ubiquitin-conjugating enzyme
E2-binding protein 1) (UbcH7-binding protein)
(UbcM4-interacting protein) (HHARI) (H7-AP2) (MOP-6)
Length = 557
Score = 50.8 bits (120), Expect = 4e-06
Identities = 36/154 (23%), Positives = 63/154 (40%), Gaps = 11/154 (7%)
Frame = +1
Query: 49 CLLCNDEKDECEKVKLKCNHVFCWICFEKYL-----KINLSVTIKCPVVSCQEIIHDDQI 213
C +C L+C H FC C+ +YL + + TI CP C ++ D+ +
Sbjct: 186 CQICYLNYPNSYFTGLECGHKFCMQCWSEYLTTKIMEEGMGQTISCPAHGCDILVDDNTV 245
Query: 214 RKVLCWEDLE-KYENLCLKDFTKAH----YCLLPQCRIPVFYQDPNVQFECANCSLYNCI 378
+++ ++ KY++L F + + +C P C V Q P+ + C C
Sbjct: 246 MRLITDSKVKLKYQHLITNSFVECNRLLKWCPAPDCHHVVKVQYPDAKPVRCKCGRQFCF 305
Query: 379 KC-QAAHGFIGCKAYQSKPSKNKVKVCEGRDDIS 477
C + H + CK K +K C+ + S
Sbjct: 306 NCGENWHDPVKCKWL-----KKWIKKCDDDSETS 334
>sp|Q9Z1K5|ARI1_MOUSE Ariadne-1 protein homolog (ARI-1) (Ubiquitin-conjugating enzyme
E2-binding protein 1) (UbcH7-binding protein)
(UbcM4-interacting protein 77)
Length = 555
Score = 50.8 bits (120), Expect = 4e-06
Identities = 36/154 (23%), Positives = 63/154 (40%), Gaps = 11/154 (7%)
Frame = +1
Query: 49 CLLCNDEKDECEKVKLKCNHVFCWICFEKYL-----KINLSVTIKCPVVSCQEIIHDDQI 213
C +C L+C H FC C+ +YL + + TI CP C ++ D+ +
Sbjct: 184 CQICYLNYPNSYFTGLECGHKFCMQCWSEYLTTKIMEEGMGQTISCPAHGCDILVDDNTV 243
Query: 214 RKVLCWEDLE-KYENLCLKDFTKAH----YCLLPQCRIPVFYQDPNVQFECANCSLYNCI 378
+++ ++ KY++L F + + +C P C V Q P+ + C C
Sbjct: 244 MRLITDSKVKLKYQHLITNSFVECNRLLKWCPAPDCHHVVKVQYPDAKPVRCKCGRQFCF 303
Query: 379 KC-QAAHGFIGCKAYQSKPSKNKVKVCEGRDDIS 477
C + H + CK K +K C+ + S
Sbjct: 304 NCGENWHDPVKCKWL-----KKWIKKCDDDSETS 332
>sp|P36113|YKZ7_YEAST Hypothetical 63.6 kDa protein in YPT52-GCN3 intergenic region
Length = 551
Score = 50.8 bits (120), Expect = 4e-06
Identities = 31/123 (25%), Positives = 52/123 (42%), Gaps = 5/123 (4%)
Frame = +1
Query: 49 CLLCNDEKDECEKVKLKCNHVFCWICFEKYLKINLSVTIKCPVVSCQEIIHDDQIRKVLC 228
C++C D+KD E L+C H +C C+ Y+K L + C + ++ I KV+
Sbjct: 179 CIICCDKKDT-ETFALECGHEYCINCYRHYIKDKLHEGNIITCMDCSLALKNEDIDKVMG 237
Query: 229 WEDLEKYENLCLKDFTKAH-----YCLLPQCRIPVFYQDPNVQFECANCSLYNCIKCQAA 393
K + +K F + H +C C+ V +D + E +KC +
Sbjct: 238 HPSSSKLMDSSIKSFVQKHNRNYKWCPFADCKSIVHLRDTSSLPEYTRLHYSPFVKCNSF 297
Query: 394 HGF 402
H F
Sbjct: 298 HRF 300
>sp|Q9Z1K6|ARI2_MOUSE Ariadne-2 protein homolog (ARI-2) (Triad1 protein)
(UbcM4-interacting protein 48)
Length = 492
Score = 50.4 bits (119), Expect = 5e-06
Identities = 32/123 (26%), Positives = 56/123 (45%), Gaps = 10/123 (8%)
Frame = +1
Query: 49 CLLCNDEKDECEKVKLKCNHVFCWICFEKY----LKINLSVTIKCPVVSCQEIIHDDQIR 216
C +C + + L C H FC C+E++ +K + V I C C +D +
Sbjct: 138 CAVCMQFVRKENLLSLACQHQFCRSCWEQHCSVLVKDGVGVGISCMAQDCPLRTPEDFVF 197
Query: 217 KVLCWEDL-EKYENLCLKDFTKAHY----CLLPQCRIPVFYQDPNV-QFECANCSLYNCI 378
+L E+L +KY +D+ ++H+ C C + + Q+P + +C CS C
Sbjct: 198 PLLPNEELRDKYRRYLFRDYVESHFQLQLCPGADCPMVIRVQEPRARRVQCNRCSEVFCF 257
Query: 379 KCQ 387
KC+
Sbjct: 258 KCR 260
Score = 32.0 bits (71), Expect = 1.9
Identities = 11/28 (39%), Positives = 17/28 (60%), Gaps = 1/28 (3%)
Frame = +1
Query: 46 KCLLCNDEKDECEKVKL-KCNHVFCWIC 126
KC +C ++ C ++ KC H FCW+C
Sbjct: 298 KCNICIEKNGGCNHMQCSKCKHDFCWMC 325
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 79,633,163
Number of Sequences: 369166
Number of extensions: 1617193
Number of successful extensions: 4384
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 4087
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4359
length of database: 68,354,980
effective HSP length: 108
effective length of database: 48,403,600
effective search space used: 7066925600
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)