Planaria EST Database


DrC_01307

BLASTX 2.2.13 [Nov-27-2005]

Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= DrC_01307
         (758 letters)

Database: Non-redundant SwissProt sequences 
           184,735 sequences; 68,354,980 total letters



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

sp|Q9H0M4|ZCPW1_HUMAN  Zinc finger CW-type PWWP domain prote...   102   9e-22
sp|Q6IR42|ZCPW1_MOUSE  Zinc finger CW-type PWWP domain prote...    99   9e-21
sp|P52701|MSH6_HUMAN  DNA mismatch repair protein MSH6 (MutS...    60   5e-09
sp|P54276|MSH6_MOUSE  DNA mismatch repair protein MSH6 (MutS...    60   6e-09
sp|Q8MT36|MES4_DROME  Probable histone methyltransferase Mes...    46   1e-04
sp|Q96L73|NSD1_HUMAN  Histone-lysine N-methyltransferase, H3...    42   0.002
sp|O88509|DNM3B_MOUSE  DNA (cytosine-5)-methyltransferase 3B...    39   0.012
sp|Q9UBC3|DNM3B_HUMAN  DNA (cytosine-5)-methyltransferase 3B...    38   0.034
sp|P47405|RL29_MYCGE  50S ribosomal protein L29                    36   0.098
sp|O88508|DNM3A_MOUSE  DNA (cytosine-5)-methyltransferase 3A...    33   0.83 
>sp|Q9H0M4|ZCPW1_HUMAN Zinc finger CW-type PWWP domain protein 1
          Length = 494

 Score =  102 bits (255), Expect = 9e-22
 Identities = 55/160 (34%), Positives = 88/160 (55%), Gaps = 3/160 (1%)
 Frame = +2

Query: 26  LNPSDIPSTWTCEMANNKSLN-CTVPEENFENSADYFINNNYTLGSVVWAKAPGFCWWPA 202
           ++PS +P  W+C+   +   N C +PEE +          +Y  GS++WAK  G+ WWP 
Sbjct: 274 IDPSVLPDNWSCDQNTDVQYNRCDIPEETWTGLESDVAYASYIPGSIIWAKQYGYPWWPG 333

Query: 203 LIDDDPDLNMFYWCYDHSNDV-SHYHVTFLDDDVSRSWITTKDVKVFRG-KADMSSMKFA 376
           +I+ DPDL  ++    H + + S YHVTF  + VSR+WI    +K F+    ++S MK  
Sbjct: 334 MIESDPDLGEYFLFTSHLDSLPSKYHVTFFGETVSRAWIPVNMLKNFQELSLELSVMK-- 391

Query: 377 KSKKDYLKLLTKAAERAEECLTLSLQKRLDKYSFAVRFTG 496
           K + D  + L  A   A+E   +S+Q+R++ + F  RF G
Sbjct: 392 KRRNDCSQKLGVALMMAQEAEQISIQERVNLFGFWSRFNG 431
>sp|Q6IR42|ZCPW1_MOUSE Zinc finger CW-type PWWP domain protein 1 homolog
          Length = 630

 Score = 99.4 bits (246), Expect = 9e-21
 Identities = 69/246 (28%), Positives = 114/246 (46%), Gaps = 4/246 (1%)
 Frame = +2

Query: 26  LNPSDIPSTWTCEMANNKSLN-CTVPEENFENSADYFINNNYTLGSVVWAKAPGFCWWPA 202
           ++PS +P  W+C+   + + N C +PEE++          +Y  GS++WAK  G+ WWP 
Sbjct: 265 IDPSVLPDDWSCDQNPDPNYNRCDIPEESWAGCESDVAYASYVPGSIIWAKQYGYPWWPG 324

Query: 203 LIDDDPDLNMFYWCYDHSNDV-SHYHVTFLDDDVSRSWITTKDVKVFRGKADMSSMKFAK 379
           +I+ DPDL  ++    H + + S YHVTF  + VSR+WI  + +K F+ +  +  +K  K
Sbjct: 325 MIEADPDLGEYFLFASHLDSLPSKYHVTFFGETVSRAWIPVRMLKNFQ-ELSLELVKKCK 383

Query: 380 SKKDYLKL--LTKAAERAEECLTLSLQKRLDKYSFAVRFTGKPNVWTSKKHTATKRKIKS 553
           +K    KL      A RAE+    S+Q+R++ + F  R+ G                   
Sbjct: 384 NKNPNQKLEAAIAMAHRAEQ---TSIQERVNLFGFWSRYNG------------------- 421

Query: 554 QPNNSDSDDESTGTKLTACSNKNEMKIKTERKVQDLKIAVAKIEAKTDNLVKLNQSTKYD 733
                 +D    G  LT C + N      E++ +DL+    + E K D  +   +  K  
Sbjct: 422 ------ADISEEGEDLTLCESNNPESC-LEKEEKDLEEEKEEEEEKKDPTLPRPKPAKMQ 474

Query: 734 LIKKNS 751
             K  S
Sbjct: 475 TKKPKS 480
>sp|P52701|MSH6_HUMAN DNA mismatch repair protein MSH6 (MutS-alpha 160 kDa subunit) (G/T
           mismatch binding protein) (GTBP) (GTMBP) (p160)
          Length = 1360

 Score = 60.5 bits (145), Expect = 5e-09
 Identities = 50/190 (26%), Positives = 82/190 (43%), Gaps = 5/190 (2%)
 Frame = +2

Query: 143 NYTLGSVVWAKAPGFCWWPALIDDDPDLNMFYWCYDHSNDVSHYHVTFLDDDVSRSWITT 322
           +++ G +VWAK  G+ WWP L+ + P    F             HV F DD  +R W++ 
Sbjct: 89  DFSPGDLVWAKMEGYPWWPCLVYNHPFDGTF---IREKGKSVRVHVQFFDDSPTRGWVSK 145

Query: 323 KDVKVFRGKADMSSMK---FAKSKKDYLKLLTKAAERAEECLTLSLQKRLDKYSFAVRFT 493
           + +K + G     + K   F  +K + L    +A +RA+E L     KRL+         
Sbjct: 146 RLLKPYTGSKSKEAQKGGHFYSAKPEIL----RAMQRADEALNKDKIKRLE--LAVCDEP 199

Query: 494 GKPNVWTSKKHTATKRKIKSQPNNSDSDDESTGTKLTACSNKNEMKIKTERKVQDLK--I 667
            +P      +   T    KS+ +N    +E    K T  S ++  +IK  R + D +  I
Sbjct: 200 SEPEEEEEMEVGTTYVTDKSEEDNEIESEEEVQPK-TQGSRRSSRQIKKRRVISDSESDI 258

Query: 668 AVAKIEAKTD 697
             + +E K D
Sbjct: 259 GGSDVEFKPD 268
>sp|P54276|MSH6_MOUSE DNA mismatch repair protein MSH6 (MutS-alpha 160 kDa subunit) (G/T
           mismatch binding protein) (GTBP) (GTMBP) (p160)
          Length = 1358

 Score = 60.1 bits (144), Expect = 6e-09
 Identities = 48/192 (25%), Positives = 85/192 (44%), Gaps = 7/192 (3%)
 Frame = +2

Query: 143 NYTLGSVVWAKAPGFCWWPALIDDDPDLNMFYWCYDHSNDVSHYHVTFLDDDVSRSWITT 322
           +++ G +VWAK  G+ WWP L+ + P    F      S  V   HV F DD  +R W++ 
Sbjct: 89  DFSPGDLVWAKMEGYPWWPCLVYNHPFDGTFIRKKGKSVRV---HVQFFDDSPTRGWVSK 145

Query: 323 KDVKVFRGKADMSSMK---FAKSKKDYLKLLTKAAERAEECLTLSLQKRLDKYSFAVRFT 493
           + +K + G     + K   F  SK + L    +A +RA+E L+    +RL      +   
Sbjct: 146 RMLKPYTGSKSKEAQKGGHFYSSKSEIL----RAMQRADEALSKDTAERLQ-----LAVC 196

Query: 494 GKPNVWTSKKHTATKRKIKSQPNNSDSDDESTGTKLTACS--NKNEMKIKTERKVQDLK- 664
            +P+    ++ T       S  +  D+ +ES      +     ++  ++K  R + D + 
Sbjct: 197 DEPSEPEEEEETEVHEAYLSDKSEEDNYNESEEEAQPSVQGPRRSSRQVKKRRVISDSES 256

Query: 665 -IAVAKIEAKTD 697
            I  + +E K D
Sbjct: 257 DIGGSDVEFKPD 268
>sp|Q8MT36|MES4_DROME Probable histone methyltransferase Mes-4 (Maternal-effect sterile 4)
          Length = 1427

 Score = 46.2 bits (108), Expect = 1e-04
 Identities = 50/231 (21%), Positives = 88/231 (38%), Gaps = 35/231 (15%)
 Frame = +2

Query: 146  YTLGSVVWAKAPGFCWWPALIDDDP--------DLNMFYWCYDHSNDVSHYHVTFLDDDV 301
            Y +G + W K   +C+WP ++  DP          +      D++N     HV F  D+ 
Sbjct: 393  YQVGDLFWGKVFSYCFWPCMVCPDPLGQIVGNMPSHPQRSSLDNANVPIQVHVRFFADNG 452

Query: 302  SRSWITTKDVKVFRGKADMSSM----------KFAK-----SKKDYLKLLTKAAERAEEC 436
             R+WI  +++  F G      M          K AK      K+  + +  +A E A+  
Sbjct: 453  RRNWIKPENLLTFAGLKAFDDMREELRIKHGPKSAKYRQMVPKRTKVVIWRQAIEEAQAM 512

Query: 437  LTLSLQKRLDKYSFAVRFTGKPNVWTSKKHTATKRKIKSQP---------NNSDSDDEST 589
              +    RL+K+     +    NV T  +    + K   Q          +++D+     
Sbjct: 513  TQIPYSDRLEKF-----YQTYENVVTLNRQKRKRTKYMMQDTSDVGSSLYDSTDNLHNKQ 567

Query: 590  GTKLTACSNKNEMKIKTERKVQDLKIAVAKIEAKTDNLV---KLNQSTKYD 733
            GT+L A        +K ER       A + +++K +      KL+  T+ D
Sbjct: 568  GTQLLA--------VKRERSESPFSPAFSPVKSKNEKRAKRRKLSNGTEAD 610

 Score = 32.0 bits (71), Expect = 1.9
 Identities = 11/18 (61%), Positives = 13/18 (72%)
 Frame = +2

Query: 155  GSVVWAKAPGFCWWPALI 208
            G +VWAK   F WWPA+I
Sbjct: 1050 GEIVWAKFNNFRWWPAII 1067
>sp|Q96L73|NSD1_HUMAN Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20
           specific (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear
           receptor binding SET domain containing protein 1)
           (NR-binding SET domain containing protein) (Androgen
           receptor-associated coregulator 267)
          Length = 2696

 Score = 41.6 bits (96), Expect = 0.002
 Identities = 20/69 (28%), Positives = 31/69 (44%), Gaps = 1/69 (1%)
 Frame = +2

Query: 146 YTLGSVVWAKAPGFCWWPALIDDDPDLNMF-YWCYDHSNDVSHYHVTFLDDDVSRSWITT 322
           Y +G ++WAK     WWP  I  DP +N        +      Y+V    D   R+W+  
Sbjct: 321 YEVGDLIWAKFKRRPWWPCRICSDPLINTHSKMKVSNRRPYRQYYVEAFGDPSERAWVAG 380

Query: 323 KDVKVFRGK 349
           K + +F G+
Sbjct: 381 KAIVMFEGR 389

 Score = 32.3 bits (72), Expect = 1.4
 Identities = 46/171 (26%), Positives = 66/171 (38%), Gaps = 12/171 (7%)
 Frame = +2

Query: 71   NNKSLNCTVPEENFENSADYFINNNYTLGSVVWAKAPGFCWWPALIDDDPDLNMFYWCYD 250
            + + LN  +PE N+  + D           +VW K   + WWPA I           C+ 
Sbjct: 1730 HRECLNIDIPEGNWYCN-DCKAGKKPHYREIVWVKVGRYRWWPAEI-----------CHP 1777

Query: 251  HS---------NDVSHYHVTFLDDDVSRSWITTKDVKVF-RGKADMSSM-KFAKS-KKDY 394
             +         +DV  + V F     S  ++ T   +VF   + D+SS  K  K     Y
Sbjct: 1778 RAVPSNIDKMRHDVGEFPVLFFG---SNDYLWTHQARVFPYMEGDVSSKDKMGKGVDGTY 1834

Query: 395  LKLLTKAAERAEECLTLSLQKRLDKYSFAVRFTGKPNVWTSKKHTATKRKI 547
             K L +AA R EE   L  QK L +     +   KP  +   KH    R I
Sbjct: 1835 KKALQEAAARFEE---LKAQKELRQLQEDRKNDKKPPPY---KHIKVNRPI 1879
>sp|O88509|DNM3B_MOUSE DNA (cytosine-5)-methyltransferase 3B (Dnmt3b) (DNA
           methyltransferase MmuIIIB) (DNA MTase MmuIIIB)
           (M.MmuIIIB)
          Length = 859

 Score = 39.3 bits (90), Expect = 0.012
 Identities = 19/70 (27%), Positives = 35/70 (50%), Gaps = 4/70 (5%)
 Frame = +2

Query: 11  DFPDILNPSDI--PSTWTCEMANNKSLNCTV--PEENFENSADYFINNNYTLGSVVWAKA 178
           DF + + P  +  PS    +  + + ++ T    E    +S +Y  +  + +G +VW K 
Sbjct: 181 DFMEEVTPKSVSTPSVDLSQDGDQEGMDTTQVDAESRDGDSTEYQDDKEFGIGDLVWGKI 240

Query: 179 PGFCWWPALI 208
            GF WWPA++
Sbjct: 241 KGFSWWPAMV 250
>sp|Q9UBC3|DNM3B_HUMAN DNA (cytosine-5)-methyltransferase 3B (Dnmt3b) (DNA
           methyltransferase HsaIIIB) (DNA MTase HsaIIIB)
           (M.HsaIIIB)
          Length = 853

 Score = 37.7 bits (86), Expect = 0.034
 Identities = 12/31 (38%), Positives = 20/31 (64%)
 Frame = +2

Query: 116 NSADYFINNNYTLGSVVWAKAPGFCWWPALI 208
           +S++Y     + +G +VW K  GF WWPA++
Sbjct: 213 DSSEYQDGKEFGIGDLVWGKIKGFSWWPAMV 243
>sp|P47405|RL29_MYCGE 50S ribosomal protein L29
          Length = 200

 Score = 36.2 bits (82), Expect = 0.098
 Identities = 37/149 (24%), Positives = 58/149 (38%), Gaps = 19/149 (12%)
 Frame = +2

Query: 368 KFAKSKKDYLKLLTKAAERAEECLTLSLQKRL------DKYSFAVRFTGK--PNVWTSK- 520
           K A  + D   L+ K  +     LT+  +++L      DKY    R T +   N W  K 
Sbjct: 32  KLAHGELDKPHLIAKVRKLLAVVLTILTERKLNWQVEKDKYKLLSRKTNELIVNSWKQKL 91

Query: 521 ----------KHTATKRKIKSQPNNSDSDDESTGTKLTACSNKNEMKIKTERKVQDLKIA 670
                     K    K K++S+P +     ++    L   + K E+K K E K   LK  
Sbjct: 92  STKPESKQETKKAEVKPKVESKPESKQETKKAEVKPLKQETKKVEVKPKVEPK--PLKQE 149

Query: 671 VAKIEAKTDNLVKLNQSTKYDLIKKNSTK 757
             K+EA+ +   K+        +KK   K
Sbjct: 150 TKKVEARIETKTKVESKPLKQEVKKVEAK 178
>sp|O88508|DNM3A_MOUSE DNA (cytosine-5)-methyltransferase 3A (Dnmt3a) (DNA
           methyltransferase MmuIIIA) (DNA MTase MmuIIIA)
           (M.MmuIIIA)
          Length = 908

 Score = 33.1 bits (74), Expect = 0.83
 Identities = 11/32 (34%), Positives = 17/32 (53%)
 Frame = +2

Query: 113 ENSADYFINNNYTLGSVVWAKAPGFCWWPALI 208
           ++  +Y     + +G +VW K  GF WWP  I
Sbjct: 275 DDEPEYEDGRGFGIGELVWGKLRGFSWWPGRI 306
  Database: Non-redundant SwissProt sequences
    Posted date:  Dec 6, 2005  7:40 AM
  Number of letters in database: 68,354,980
  Number of sequences in database:  184,735
  
  Database: swissprot.01
    Posted date:  Dec 6, 2005  8:18 AM
  Number of letters in database: 66,202,850
  Number of sequences in database:  184,431
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 75,378,718
Number of Sequences: 369166
Number of extensions: 1327256
Number of successful extensions: 4550
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 4318
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4530
length of database: 68,354,980
effective HSP length: 108
effective length of database: 48,403,600
effective search space used: 6970118400
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)