Planaria EST Database


DrC_01286

BLASTX 2.2.13 [Nov-27-2005]

Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= DrC_01286
         (574 letters)

Database: Non-redundant SwissProt sequences 
           184,735 sequences; 68,354,980 total letters



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

sp|Q12965|MYO1E_HUMAN  Myosin Ie (Myosin Ic)                       72   8e-13
sp|Q63356|MYO1E_RAT  Myosin Ie (Myosin heavy chain myr 3)          72   1e-12
sp|P80192|M3K9_HUMAN  Mitogen-activated protein kinase kinas...    66   7e-11
sp|Q9JLQ0|CD2AP_MOUSE  CD2-associated protein (Mesenchym-to-...    64   3e-10
sp|O89100|GRAP2_MOUSE  GRB2-related adaptor protein 2 (GADS ...    64   3e-10
sp|P70248|MYO1F_MOUSE  Myosin If                                   62   8e-10
sp|O00160|MYO1F_HUMAN  Myosin If (Myosin-IE)                       62   8e-10
sp|Q9Y5K6|CD2AP_HUMAN  CD2-associated protein (Cas ligand wi...    62   1e-09
sp|O75791|GRAP2_HUMAN  GRB2-related adaptor protein 2 (GADS ...    62   1e-09
sp|Q96B97|SH3K1_HUMAN  SH3-domain kinase binding protein 1 (...    61   2e-09
>sp|Q12965|MYO1E_HUMAN Myosin Ie (Myosin Ic)
          Length = 1109

 Score = 72.4 bits (176), Expect = 8e-13
 Identities = 34/82 (41%), Positives = 47/82 (57%)
 Frame = +3

Query: 228  GVKRDDNAKDKVIXXXXXXXXXXXXXVNKVEALYDYEATDTDELTIRIGDIIELIKEDNE 407
            GV+R   ++                 V + +ALY Y+A DTDEL+    DII++IKED  
Sbjct: 1028 GVRRQTTSRPPPAGGRPKPQPKPKPQVPQCKALYAYDAQDTDELSFNANDIIDIIKEDPS 1087

Query: 408  GWWTGKIGNRTGLMPSNYVKKI 473
            GWWTG++  + GL P+NYV KI
Sbjct: 1088 GWWTGRLRGKPGLFPNNYVTKI 1109
>sp|Q63356|MYO1E_RAT Myosin Ie (Myosin heavy chain myr 3)
          Length = 1107

 Score = 72.0 bits (175), Expect = 1e-12
 Identities = 33/82 (40%), Positives = 47/82 (57%)
 Frame = +3

Query: 228  GVKRDDNAKDKVIXXXXXXXXXXXXXVNKVEALYDYEATDTDELTIRIGDIIELIKEDNE 407
            GV+R   ++                 V + +ALY Y+A DTDEL+    D+I++IKED  
Sbjct: 1026 GVRRQTTSRPPPAGGRPKPQPKPKPQVPQCKALYAYDAQDTDELSFNANDVIDIIKEDPS 1085

Query: 408  GWWTGKIGNRTGLMPSNYVKKI 473
            GWWTG++  + GL P+NYV KI
Sbjct: 1086 GWWTGRLRGKQGLFPNNYVTKI 1107
>sp|P80192|M3K9_HUMAN Mitogen-activated protein kinase kinase kinase 9 (Mixed lineage
           kinase 1)
          Length = 1104

 Score = 65.9 bits (159), Expect = 7e-11
 Identities = 26/53 (49%), Positives = 40/53 (75%), Gaps = 5/53 (9%)
 Frame = +3

Query: 321 ALYDYEATDTDELTIRIGDIIELIKED-----NEGWWTGKIGNRTGLMPSNYV 464
           A+++YEA   DELT+R+GD++E++ +D     +EGWWTG++  R G+ PSNYV
Sbjct: 59  AVFEYEAAGEDELTLRLGDVVEVLSKDSQVSGDEGWWTGQLNQRVGIFPSNYV 111
>sp|Q9JLQ0|CD2AP_MOUSE CD2-associated protein (Mesenchym-to-epithelium transition protein
           with SH3 domains 1) (METS-1)
          Length = 637

 Score = 63.9 bits (154), Expect = 3e-10
 Identities = 24/52 (46%), Positives = 39/52 (75%)
 Frame = +3

Query: 318 EALYDYEATDTDELTIRIGDIIELIKEDNEGWWTGKIGNRTGLMPSNYVKKI 473
           + L+DY   + DEL + +GD+I++I+E  EGWW+G + N+ GL PSN+VK++
Sbjct: 114 KVLFDYSPQNEDELELIVGDVIDVIEEVEEGWWSGTLNNKLGLFPSNFVKEL 165

 Score = 57.0 bits (136), Expect = 3e-08
 Identities = 25/50 (50%), Positives = 35/50 (70%), Gaps = 1/50 (2%)
 Frame = +3

Query: 327 YDYEATDTDELTIRIGDIIELIKE-DNEGWWTGKIGNRTGLMPSNYVKKI 473
           YDY+A   DELTIR+G+II  +K+   EGW  G++  R G+ P N+VK+I
Sbjct: 8   YDYDAVHDDELTIRVGEIIRNVKKLQEEGWLEGELNGRRGMFPDNFVKEI 57

 Score = 49.3 bits (116), Expect = 7e-06
 Identities = 24/52 (46%), Positives = 33/52 (63%), Gaps = 2/52 (3%)
 Frame = +3

Query: 324 LYDYEATDTDELTIRIGDIIELI-KEDNE-GWWTGKIGNRTGLMPSNYVKKI 473
           L+ Y  T+ DELT R G+II LI KE  E GWW G++  + G+ P N+  +I
Sbjct: 277 LFPYTGTNEDELTFREGEIIHLISKETGEAGWWKGELNGKEGVFPDNFAVQI 328
>sp|O89100|GRAP2_MOUSE GRB2-related adaptor protein 2 (GADS protein) (Growth factor
           receptor binding protein) (GRBLG) (GRB-2-like protein)
           (GRB2L) (Hematopoietic cell-associated adaptor protein
           GrpL) (GRB-2-related monocytic adapter protein)
           (Monocytic adapter) (MONA) (Adapter protein GRID)
          Length = 322

 Score = 63.5 bits (153), Expect = 3e-10
 Identities = 25/53 (47%), Positives = 36/53 (67%)
 Frame = +3

Query: 306 VNKVEALYDYEATDTDELTIRIGDIIELIKEDNEGWWTGKIGNRTGLMPSNYV 464
           V    ALYD+EA + DEL  R G+++E++   N  WWTG++ N+ GL P+NYV
Sbjct: 265 VRWARALYDFEALEEDELGFRSGEVVEVLDSSNPSWWTGRLHNKLGLFPANYV 317

 Score = 40.8 bits (94), Expect = 0.002
 Identities = 16/48 (33%), Positives = 31/48 (64%)
 Frame = +3

Query: 321 ALYDYEATDTDELTIRIGDIIELIKEDNEGWWTGKIGNRTGLMPSNYV 464
           A +D+ A+  DEL+ R GDI++++    E W   ++G++ G +P N++
Sbjct: 5   AKFDFMASGEDELSFRTGDILKILSNQEE-WLKAELGSQEGYVPKNFI 51
>sp|P70248|MYO1F_MOUSE Myosin If
          Length = 1099

 Score = 62.4 bits (150), Expect = 8e-10
 Identities = 24/54 (44%), Positives = 36/54 (66%)
 Frame = +3

Query: 312  KVEALYDYEATDTDELTIRIGDIIELIKEDNEGWWTGKIGNRTGLMPSNYVKKI 473
            +  ALY Y   D DEL+  + ++IE++ ED+ GWW G++  + GL P NYV+KI
Sbjct: 1046 RCRALYQYIGQDVDELSFNVNEVIEILIEDSSGWWKGRLHGQEGLFPGNYVEKI 1099
>sp|O00160|MYO1F_HUMAN Myosin If (Myosin-IE)
          Length = 1098

 Score = 62.4 bits (150), Expect = 8e-10
 Identities = 24/54 (44%), Positives = 35/54 (64%)
 Frame = +3

Query: 312  KVEALYDYEATDTDELTIRIGDIIELIKEDNEGWWTGKIGNRTGLMPSNYVKKI 473
            +  ALY Y   D DEL+  + ++IE++ ED  GWW G++  + GL P NYV+KI
Sbjct: 1045 RCRALYQYVGQDVDELSFNVNEVIEILMEDPSGWWKGRLHGQEGLFPGNYVEKI 1098
>sp|Q9Y5K6|CD2AP_HUMAN CD2-associated protein (Cas ligand with multiple SH3 domains)
           (Adapter protein CMS)
          Length = 639

 Score = 62.0 bits (149), Expect = 1e-09
 Identities = 25/62 (40%), Positives = 43/62 (69%)
 Frame = +3

Query: 318 EALYDYEATDTDELTIRIGDIIELIKEDNEGWWTGKIGNRTGLMPSNYVKKI*FNNFFYT 497
           + L++Y   + DEL +++GDII++ +E  EGWW+G + N+ GL PSN+VK++   +   T
Sbjct: 114 KVLFEYIPQNEDELELKVGDIIDINEEVEEGWWSGTLNNKLGLFPSNFVKELEVTDDGET 173

Query: 498 HK 503
           H+
Sbjct: 174 HE 175

 Score = 57.0 bits (136), Expect = 3e-08
 Identities = 25/50 (50%), Positives = 35/50 (70%), Gaps = 1/50 (2%)
 Frame = +3

Query: 327 YDYEATDTDELTIRIGDIIELIKE-DNEGWWTGKIGNRTGLMPSNYVKKI 473
           YDY+A   DELTIR+G+II  +K+   EGW  G++  R G+ P N+VK+I
Sbjct: 8   YDYDAVHDDELTIRVGEIIRNVKKLQEEGWLEGELNGRRGMFPDNFVKEI 57

 Score = 50.1 bits (118), Expect = 4e-06
 Identities = 24/52 (46%), Positives = 34/52 (65%), Gaps = 2/52 (3%)
 Frame = +3

Query: 324 LYDYEATDTDELTIRIGDIIELI-KEDNE-GWWTGKIGNRTGLMPSNYVKKI 473
           L+ YE T+ DELT + G+II LI KE  E GWW G++  + G+ P N+  +I
Sbjct: 277 LFAYEGTNEDELTFKEGEIIHLISKETGEAGWWRGELNGKEGVFPDNFAVQI 328
>sp|O75791|GRAP2_HUMAN GRB2-related adaptor protein 2 (GADS protein) (Growth factor
           receptor binding protein) (GRBLG) (Grf40 adaptor
           protein) (Grf-40) (GRB-2-like protein) (GRB2L) (GRBX)
           (P38) (Hematopoietic cell-associated adaptor protein
           GrpL) (Adapter protein GRID) (SH3-SH2-SH3 adaptor Mona)
          Length = 330

 Score = 61.6 bits (148), Expect = 1e-09
 Identities = 24/53 (45%), Positives = 35/53 (66%)
 Frame = +3

Query: 306 VNKVEALYDYEATDTDELTIRIGDIIELIKEDNEGWWTGKIGNRTGLMPSNYV 464
           V    ALYD+EA + DEL    G+++E++   N  WWTG++ N+ GL P+NYV
Sbjct: 273 VRWARALYDFEALEDDELGFHSGEVVEVLDSSNPSWWTGRLHNKLGLFPANYV 325

 Score = 40.0 bits (92), Expect = 0.004
 Identities = 14/48 (29%), Positives = 31/48 (64%)
 Frame = +3

Query: 321 ALYDYEATDTDELTIRIGDIIELIKEDNEGWWTGKIGNRTGLMPSNYV 464
           A +D+ A+  DEL+   GD+++++    E W+  ++G++ G +P N++
Sbjct: 5   AKFDFTASGEDELSFHTGDVLKILSNQEE-WFKAELGSQEGYVPKNFI 51
>sp|Q96B97|SH3K1_HUMAN SH3-domain kinase binding protein 1 (Cbl-interacting protein of 85
           kDa) (Human Src-family kinase binding protein 1) (HSB-1)
           (CD2 binding protein 3) (CD2BP3)
          Length = 665

 Score = 60.8 bits (146), Expect = 2e-09
 Identities = 27/55 (49%), Positives = 40/55 (72%), Gaps = 2/55 (3%)
 Frame = +3

Query: 315 VEAL--YDYEATDTDELTIRIGDIIELIKEDNEGWWTGKIGNRTGLMPSNYVKKI 473
           VEA+  +DY+A   DELTI +G+II  I++++ GWW G+I  R GL P N+V++I
Sbjct: 2   VEAIVEFDYQAQHDDELTISVGEIITNIRKEDGGWWEGQINGRRGLFPDNFVREI 56

 Score = 58.9 bits (141), Expect = 9e-09
 Identities = 21/54 (38%), Positives = 37/54 (68%)
 Frame = +3

Query: 312 KVEALYDYEATDTDELTIRIGDIIELIKEDNEGWWTGKIGNRTGLMPSNYVKKI 473
           + +  + Y   + DEL +++GDIIE++ E  EGWW G +  +TG+ PSN++K++
Sbjct: 102 RCQVAFSYLPQNDDELELKVGDIIEVVGEVEEGWWEGVLNGKTGMFPSNFIKEL 155

 Score = 56.2 bits (134), Expect = 6e-08
 Identities = 24/52 (46%), Positives = 36/52 (69%), Gaps = 2/52 (3%)
 Frame = +3

Query: 318 EALYDYEATDTDELTIRIGDIIELIKED--NEGWWTGKIGNRTGLMPSNYVK 467
           + ++ YEA + DELTI+ GDI+ LI +D  + GWW G++  R G+ P N+VK
Sbjct: 273 KVIFPYEAQNDDELTIKEGDIVTLINKDCIDVGWWEGELNGRRGVFPDNFVK 324
  Database: Non-redundant SwissProt sequences
    Posted date:  Dec 6, 2005  7:40 AM
  Number of letters in database: 68,354,980
  Number of sequences in database:  184,735
  
  Database: swissprot.01
    Posted date:  Dec 6, 2005  8:18 AM
  Number of letters in database: 66,202,850
  Number of sequences in database:  184,431
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 51,004,864
Number of Sequences: 369166
Number of extensions: 844335
Number of successful extensions: 2888
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 2659
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 2796
length of database: 68,354,980
effective HSP length: 104
effective length of database: 49,142,540
effective search space used: 4226258440
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)