Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= DrC_01275 (730 letters) Database: Non-redundant SwissProt sequences 184,735 sequences; 68,354,980 total letters Score E Sequences producing significant alignments: (bits) Value sp|O73672|PSA2_CARAU Proteasome subunit alpha type 2 313 2e-85 sp|P17220|PSA2_RAT Proteasome subunit alpha type 2 (Proteas... 310 3e-84 sp|P49722|PSA2_MOUSE Proteasome subunit alpha type 2 (Prote... 310 3e-84 sp|P25787|PSA2_HUMAN Proteasome subunit alpha type 2 (Prote... 309 6e-84 sp|P24495|PSA2_XENLA Proteasome subunit alpha type 2 (Prote... 308 1e-83 sp|P40301|PSA2_DROME Proteasome subunit alpha type 2 (Prote... 299 6e-81 sp|Q8L4A7|PSA2B_ARATH Proteasome subunit alpha type 2-B (20... 270 3e-72 sp|O23708|PSA2A_ARATH Proteasome subunit alpha type 2-A (20... 268 8e-72 sp|Q9LSU2|PSA2_ORYSA Proteasome subunit alpha type 2 (20S p... 268 1e-71 sp|Q27488|PSA2_CAEEL Proteasome subunit alpha type 2 (Prote... 267 2e-71
>sp|O73672|PSA2_CARAU Proteasome subunit alpha type 2 Length = 234 Score = 313 bits (803), Expect = 2e-85 Identities = 160/229 (69%), Positives = 184/229 (80%) Frame = +3 Query: 3 SFSLTTFSPSGKLVQIEYALKAVDGGAPSVGIKACNGAVLAVEKKFNSLLIDETSIKRIQ 182 SFSLTTFSPSGKLVQIEYAL AV GAPSVGIKA NG VLA EKK S+L DE S+ +I+ Sbjct: 7 SFSLTTFSPSGKLVQIEYALAAVAAGAPSVGIKASNGVVLATEKKQKSILYDEQSVHKIE 66 Query: 183 EITTNIGFVYSGLSPDYRLLVKKAIKIADDYLLSHGNLISPEQLAKSISAVMQEYTQSGG 362 IT +IG VYSG+ PDYR+LV++A K+A Y L + I QL + +++VMQEYTQSGG Sbjct: 67 PITKHIGMVYSGMGPDYRVLVRRARKLAQQYFLVYQEPIPTGQLVQRVASVMQEYTQSGG 126 Query: 363 VRPFGVSLLIAGWDNEIDRPFLFQCDPSGTYFPWKATALGKNSGNGKSFLEKRYNDKLEL 542 VRPFGVSLLIAGWD DRP+LFQ DPSG YF WKATA+GK+ NGK+FLEKRYN+ LEL Sbjct: 127 VRPFGVSLLIAGWDE--DRPYLFQSDPSGAYFAWKATAMGKSYVNGKTFLEKRYNEDLEL 184 Query: 543 EDAIHTSILTLKESFEGVMTEENIEVAICTDKGFRILDQSEVRDYLTAI 689 EDAIHT+ILTLKESFEG MTEENIEV IC + GFR L +EV+DYL AI Sbjct: 185 EDAIHTAILTLKESFEGQMTEENIEVGICNEAGFRRLSPAEVKDYLAAI 233
>sp|P17220|PSA2_RAT Proteasome subunit alpha type 2 (Proteasome component C3) (Macropain subunit C3) (Multicatalytic endopeptidase complex subunit C3) Length = 234 Score = 310 bits (794), Expect = 3e-84 Identities = 158/229 (68%), Positives = 182/229 (79%) Frame = +3 Query: 3 SFSLTTFSPSGKLVQIEYALKAVDGGAPSVGIKACNGAVLAVEKKFNSLLIDETSIKRIQ 182 SFSLTTFSPSGKLVQIEYAL AV GGAPSVGIKA NG VLA EKK S+L DE S+ +++ Sbjct: 7 SFSLTTFSPSGKLVQIEYALAAVAGGAPSVGIKAANGVVLATEKKQKSILYDERSVHKVE 66 Query: 183 EITTNIGFVYSGLSPDYRLLVKKAIKIADDYLLSHGNLISPEQLAKSISAVMQEYTQSGG 362 IT +IG VYSG+ PDYR+LV +A K+A Y L + I QL + +++VMQEYTQSGG Sbjct: 67 PITKHIGLVYSGMGPDYRVLVHRARKLAQQYYLVYQEPIPTAQLVQRVASVMQEYTQSGG 126 Query: 363 VRPFGVSLLIAGWDNEIDRPFLFQCDPSGTYFPWKATALGKNSGNGKSFLEKRYNDKLEL 542 VRPFGVSLLI GW+ RP+LFQ DPSG YF WKATA+GKN NGK+FLEKRYN+ LEL Sbjct: 127 VRPFGVSLLICGWNE--GRPYLFQSDPSGAYFAWKATAMGKNYVNGKTFLEKRYNEDLEL 184 Query: 543 EDAIHTSILTLKESFEGVMTEENIEVAICTDKGFRILDQSEVRDYLTAI 689 EDAIHT+ILTLKESFEG MTE+NIEV IC + GFR L +EVRDYL AI Sbjct: 185 EDAIHTAILTLKESFEGQMTEDNIEVGICNEAGFRRLTPTEVRDYLAAI 233
>sp|P49722|PSA2_MOUSE Proteasome subunit alpha type 2 (Proteasome component C3) (Macropain subunit C3) (Multicatalytic endopeptidase complex subunit C3) Length = 234 Score = 310 bits (794), Expect = 3e-84 Identities = 158/229 (68%), Positives = 182/229 (79%) Frame = +3 Query: 3 SFSLTTFSPSGKLVQIEYALKAVDGGAPSVGIKACNGAVLAVEKKFNSLLIDETSIKRIQ 182 SFSLTTFSPSGKLVQIEYAL AV GGAPSVGIKA NG VLA EKK S+L DE S+ +++ Sbjct: 7 SFSLTTFSPSGKLVQIEYALAAVAGGAPSVGIKAANGVVLATEKKQKSILYDERSVHKVE 66 Query: 183 EITTNIGFVYSGLSPDYRLLVKKAIKIADDYLLSHGNLISPEQLAKSISAVMQEYTQSGG 362 IT +IG VYSG+ PDYR+LV +A K+A Y L + I QL + +++VMQEYTQSGG Sbjct: 67 PITKHIGLVYSGMGPDYRVLVHRARKLAQQYYLVYQEPIPTAQLVQRVASVMQEYTQSGG 126 Query: 363 VRPFGVSLLIAGWDNEIDRPFLFQCDPSGTYFPWKATALGKNSGNGKSFLEKRYNDKLEL 542 VRPFGVSLLI GW+ RP+LFQ DPSG YF WKATA+GKN NGK+FLEKRYN+ LEL Sbjct: 127 VRPFGVSLLICGWNE--GRPYLFQSDPSGAYFAWKATAMGKNYVNGKTFLEKRYNEDLEL 184 Query: 543 EDAIHTSILTLKESFEGVMTEENIEVAICTDKGFRILDQSEVRDYLTAI 689 EDAIHT+ILTLKESFEG MTE+NIEV IC + GFR L +EVRDYL AI Sbjct: 185 EDAIHTAILTLKESFEGQMTEDNIEVGICNEAGFRRLTPTEVRDYLAAI 233
>sp|P25787|PSA2_HUMAN Proteasome subunit alpha type 2 (Proteasome component C3) (Macropain subunit C3) (Multicatalytic endopeptidase complex subunit C3) Length = 234 Score = 309 bits (791), Expect = 6e-84 Identities = 157/229 (68%), Positives = 182/229 (79%) Frame = +3 Query: 3 SFSLTTFSPSGKLVQIEYALKAVDGGAPSVGIKACNGAVLAVEKKFNSLLIDETSIKRIQ 182 SFSLTTFSPSGKLVQIEYAL AV GGAPSVGIKA NG VLA EKK S+L DE S+ +++ Sbjct: 7 SFSLTTFSPSGKLVQIEYALAAVAGGAPSVGIKAANGVVLATEKKQKSILYDERSVHKVE 66 Query: 183 EITTNIGFVYSGLSPDYRLLVKKAIKIADDYLLSHGNLISPEQLAKSISAVMQEYTQSGG 362 IT +IG VYSG+ PDYR+LV +A K+A Y L + I QL + +++VMQEYTQSGG Sbjct: 67 PITKHIGLVYSGMGPDYRVLVHRARKLAQQYYLVYQEPIPTAQLVQRVASVMQEYTQSGG 126 Query: 363 VRPFGVSLLIAGWDNEIDRPFLFQCDPSGTYFPWKATALGKNSGNGKSFLEKRYNDKLEL 542 VRPFGVSLLI GW+ RP+LFQ DPSG YF WKATA+GKN NGK+FLEKRYN+ LEL Sbjct: 127 VRPFGVSLLICGWNE--GRPYLFQSDPSGAYFAWKATAMGKNYVNGKTFLEKRYNEDLEL 184 Query: 543 EDAIHTSILTLKESFEGVMTEENIEVAICTDKGFRILDQSEVRDYLTAI 689 EDAIHT+ILTLKESFEG MTE+NIEV IC + GFR L +EV+DYL AI Sbjct: 185 EDAIHTAILTLKESFEGQMTEDNIEVGICNEAGFRRLTPTEVKDYLAAI 233
>sp|P24495|PSA2_XENLA Proteasome subunit alpha type 2 (Proteasome component C3) (Macropain subunit C3) (Multicatalytic endopeptidase complex subunit C3) (xC3) Length = 234 Score = 308 bits (789), Expect = 1e-83 Identities = 157/229 (68%), Positives = 182/229 (79%) Frame = +3 Query: 3 SFSLTTFSPSGKLVQIEYALKAVDGGAPSVGIKACNGAVLAVEKKFNSLLIDETSIKRIQ 182 SFSLTTFSPSGKLVQIEYAL AV GAPSVGIKA NG VLA EKK S+L DE S +++ Sbjct: 7 SFSLTTFSPSGKLVQIEYALAAVAAGAPSVGIKATNGVVLATEKKQKSILYDEQSAHKVE 66 Query: 183 EITTNIGFVYSGLSPDYRLLVKKAIKIADDYLLSHGNLISPEQLAKSISAVMQEYTQSGG 362 IT +IG VYSG+ PDYR+LV++A K+A Y L + I QL + +++VMQEYTQSGG Sbjct: 67 PITKHIGMVYSGMGPDYRVLVRRARKLAQQYYLVYQEPIPTAQLVQRVASVMQEYTQSGG 126 Query: 363 VRPFGVSLLIAGWDNEIDRPFLFQCDPSGTYFPWKATALGKNSGNGKSFLEKRYNDKLEL 542 VRPFGVSLLIAGWD RP+LFQ DPSG YF WKATA+GKN NGK+FLEKRYN+ LEL Sbjct: 127 VRPFGVSLLIAGWDE--GRPYLFQSDPSGAYFAWKATAMGKNYVNGKTFLEKRYNEDLEL 184 Query: 543 EDAIHTSILTLKESFEGVMTEENIEVAICTDKGFRILDQSEVRDYLTAI 689 EDAIHT+ILTLKESFEG MTE+NIEV IC + GF+ L +EV+DYL AI Sbjct: 185 EDAIHTAILTLKESFEGQMTEDNIEVGICNEAGFKRLTPAEVKDYLAAI 233
>sp|P40301|PSA2_DROME Proteasome subunit alpha type 2 (Proteasome 25 kDa subunit) (PROS-Dm25) Length = 234 Score = 299 bits (765), Expect = 6e-81 Identities = 147/230 (63%), Positives = 180/230 (78%) Frame = +3 Query: 3 SFSLTTFSPSGKLVQIEYALKAVDGGAPSVGIKACNGAVLAVEKKFNSLLIDETSIKRIQ 182 SFSLTTFSPSGKLVQ+EYAL AV GGAPSVGI A NG V+A E K S L ++ S+ R++ Sbjct: 7 SFSLTTFSPSGKLVQLEYALAAVSGGAPSVGIIASNGVVIATENKHKSPLYEQHSVHRVE 66 Query: 183 EITTNIGFVYSGLSPDYRLLVKKAIKIADDYLLSHGNLISPEQLAKSISAVMQEYTQSGG 362 I +IG VYSG+ PDYRLLVK+A KIA Y L++ I QL + ++ +MQEYTQSGG Sbjct: 67 MIYNHIGMVYSGMGPDYRLLVKQARKIAQTYYLTYKEPIPVSQLVQRVATLMQEYTQSGG 126 Query: 363 VRPFGVSLLIAGWDNEIDRPFLFQCDPSGTYFPWKATALGKNSGNGKSFLEKRYNDKLEL 542 VRPFGVSLLI GWDN DRP+L+Q DPSG YF WKATA+GKN+ NGK+FLEKRY++ LEL Sbjct: 127 VRPFGVSLLICGWDN--DRPYLYQSDPSGAYFAWKATAMGKNAVNGKTFLEKRYSEDLEL 184 Query: 543 EDAIHTSILTLKESFEGVMTEENIEVAICTDKGFRILDQSEVRDYLTAIP 692 +DA+HT+ILTLKE FEG MT +NIE+ IC GF+ LD + ++DYL +IP Sbjct: 185 DDAVHTAILTLKEGFEGKMTADNIEIGICDQNGFQRLDPASIKDYLASIP 234
>sp|Q8L4A7|PSA2B_ARATH Proteasome subunit alpha type 2-B (20S proteasome alpha subunit B-2) Length = 235 Score = 270 bits (690), Expect = 3e-72 Identities = 137/230 (59%), Positives = 177/230 (76%), Gaps = 1/230 (0%) Frame = +3 Query: 3 SFSLTTFSPSGKLVQIEYALKAVDGGAPSVGIKACNGAVLAVEKKFNSLLIDETSIKRIQ 182 SFSLTTFSPSGKLVQIE+AL AV G S+GIKA NG V+A EKK S+L+DE S+++IQ Sbjct: 7 SFSLTTFSPSGKLVQIEHALTAVGSGQTSLGIKASNGVVIATEKKLPSILVDEASVQKIQ 66 Query: 183 EITTNIGFVYSGLSPDYRLLVKKAIKIADDYLLSHGNLISPEQLAKSISAVMQEYTQSGG 362 +T NIG VYSG+ PD+R+LV+K+ K A+ YL + I QL + + VMQE+TQSGG Sbjct: 67 HLTPNIGTVYSGMGPDFRVLVRKSRKQAEQYLRLYKEPIPVTQLVRETATVMQEFTQSGG 126 Query: 363 VRPFGVSLLIAGWDNEIDRPFLFQCDPSGTYFPWKATALGKNSGNGKSFLEKRYNDKLEL 542 VRPFGVSLL+AG+D++ P L+Q DPSG+YF WKA+A+GKN N K+FLEKRY + +EL Sbjct: 127 VRPFGVSLLVAGYDDK--GPQLYQVDPSGSYFSWKASAMGKNVSNAKTFLEKRYTEDMEL 184 Query: 543 EDAIHTSILTLKESFEGVMTEENIEVA-ICTDKGFRILDQSEVRDYLTAI 689 +DAIHT+ILTLKE FEG ++ +NIE+ I TDK FR+L +E+ DYL + Sbjct: 185 DDAIHTAILTLKEGFEGEISSKNIEIGKIGTDKVFRVLTPAEIDDYLAEV 234
>sp|O23708|PSA2A_ARATH Proteasome subunit alpha type 2-A (20S proteasome alpha subunit B) (Proteasome component 3) Length = 235 Score = 268 bits (686), Expect = 8e-72 Identities = 136/230 (59%), Positives = 176/230 (76%), Gaps = 1/230 (0%) Frame = +3 Query: 3 SFSLTTFSPSGKLVQIEYALKAVDGGAPSVGIKACNGAVLAVEKKFNSLLIDETSIKRIQ 182 SFSLTTFSPSGKLVQIE+AL AV G S+GIKA NG V+A EKK S+L+DE S+++IQ Sbjct: 7 SFSLTTFSPSGKLVQIEHALTAVGSGQTSLGIKASNGVVIATEKKLPSILVDEASVQKIQ 66 Query: 183 EITTNIGFVYSGLSPDYRLLVKKAIKIADDYLLSHGNLISPEQLAKSISAVMQEYTQSGG 362 +T NIG VYSG+ PD+R+LV+K+ K A+ YL + I QL + + VMQE+TQSGG Sbjct: 67 HLTPNIGVVYSGMGPDFRVLVRKSRKQAEQYLRLYKEPIPVTQLVRETATVMQEFTQSGG 126 Query: 363 VRPFGVSLLIAGWDNEIDRPFLFQCDPSGTYFPWKATALGKNSGNGKSFLEKRYNDKLEL 542 VRPFGVSLL+AG+D++ P L+Q DPSG+YF WKA+A+GKN N K+FLEKRY + +EL Sbjct: 127 VRPFGVSLLVAGYDDK--GPQLYQVDPSGSYFSWKASAMGKNVSNAKTFLEKRYTEDMEL 184 Query: 543 EDAIHTSILTLKESFEGVMTEENIEVA-ICTDKGFRILDQSEVRDYLTAI 689 +DAIHT+ILTLKE FEG ++ +NIE+ I DK FR+L +E+ DYL + Sbjct: 185 DDAIHTAILTLKEGFEGEISSKNIEIGKIGADKVFRVLTPAEIDDYLAEV 234
>sp|Q9LSU2|PSA2_ORYSA Proteasome subunit alpha type 2 (20S proteasome alpha subunit B) (20S proteasome subunit alpha-2) Length = 235 Score = 268 bits (685), Expect = 1e-71 Identities = 134/230 (58%), Positives = 177/230 (76%), Gaps = 1/230 (0%) Frame = +3 Query: 3 SFSLTTFSPSGKLVQIEYALKAVDGGAPSVGIKACNGAVLAVEKKFNSLLIDETSIKRIQ 182 SFSLTTFSPSGKLVQIE+AL AV G S+GIKA NG V+A EKK S+L+DETS+++IQ Sbjct: 7 SFSLTTFSPSGKLVQIEHALTAVGSGQTSLGIKAANGVVIATEKKLPSILVDETSVQKIQ 66 Query: 183 EITTNIGFVYSGLSPDYRLLVKKAIKIADDYLLSHGNLISPEQLAKSISAVMQEYTQSGG 362 +T NIG VYSG+ PD+R+LV+K+ K A Y + I QL + +AVMQE+TQSGG Sbjct: 67 SLTPNIGVVYSGMGPDFRVLVRKSRKQAQQYYRLYKETIPVTQLVRETAAVMQEFTQSGG 126 Query: 363 VRPFGVSLLIAGWDNEIDRPFLFQCDPSGTYFPWKATALGKNSGNGKSFLEKRYNDKLEL 542 VRPFGVSLLIAG+D+ + P L+Q DPSG+YF WKA+A+GKN N K+FLEKRY + +EL Sbjct: 127 VRPFGVSLLIAGYDD--NGPQLYQVDPSGSYFSWKASAMGKNVSNAKTFLEKRYTEDMEL 184 Query: 543 EDAIHTSILTLKESFEGVMTEENIEVAIC-TDKGFRILDQSEVRDYLTAI 689 +DAIHT+ILTLKE +EG ++ NIE+ I +D+ F++L +E++D+L + Sbjct: 185 DDAIHTAILTLKEGYEGQISANNIEIGIIRSDREFKVLSPAEIKDFLEEV 234
>sp|Q27488|PSA2_CAEEL Proteasome subunit alpha type 2 (Proteasome subunit alpha 2) Length = 231 Score = 267 bits (682), Expect = 2e-71 Identities = 135/225 (60%), Positives = 169/225 (75%) Frame = +3 Query: 6 FSLTTFSPSGKLVQIEYALKAVDGGAPSVGIKACNGAVLAVEKKFNSLLIDETSIKRIQE 185 FSLTTFSPSGKL+QIEYAL AV G PSVG++A +G VLA E S+L D+ ++++ Sbjct: 7 FSLTTFSPSGKLMQIEYALNAVKNGQPSVGLRAKDGVVLATEN-VGSVLTDDQP--KVEQ 63 Query: 186 ITTNIGFVYSGLSPDYRLLVKKAIKIADDYLLSHGNLISPEQLAKSISAVMQEYTQSGGV 365 I+ +IG VYSG+ PD+R+LVKKA KIA +Y + +G + QL I+AVMQEYTQSGGV Sbjct: 64 ISKHIGCVYSGMGPDFRILVKKARKIAMEYEMMYGEEMPTIQLVTDIAAVMQEYTQSGGV 123 Query: 366 RPFGVSLLIAGWDNEIDRPFLFQCDPSGTYFPWKATALGKNSGNGKSFLEKRYNDKLELE 545 RPFG SLLIAGWD RP LFQCDPSG YF WKATALGKN N K+FLEKR+++ LEL+ Sbjct: 124 RPFGASLLIAGWDKNPGRPLLFQCDPSGAYFAWKATALGKNDVNAKTFLEKRFSEALELD 183 Query: 546 DAIHTSILTLKESFEGVMTEENIEVAICTDKGFRILDQSEVRDYL 680 D IHT++LTL+ESF+ M E N+EVA+C GF L + +V D+L Sbjct: 184 DGIHTALLTLRESFDVGMNENNVEVAVCNSTGFHRLTKQQVHDHL 228
Database: Non-redundant SwissProt sequences Posted date: Dec 6, 2005 7:40 AM Number of letters in database: 68,354,980 Number of sequences in database: 184,735 Database: swissprot.01 Posted date: Dec 6, 2005 8:18 AM Number of letters in database: 66,202,850 Number of sequences in database: 184,431 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 82,455,857 Number of Sequences: 369166 Number of extensions: 1645837 Number of successful extensions: 4828 Number of sequences better than 10.0: 10 Number of HSP's better than 10.0 without gapping: 4528 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 4645 length of database: 68,354,980 effective HSP length: 108 effective length of database: 48,403,600 effective search space used: 6486082400 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)