Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_002_N04
(730 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|O73672|PSA2_CARAU Proteasome subunit alpha type 2 313 2e-85
sp|P17220|PSA2_RAT Proteasome subunit alpha type 2 (Proteas... 310 3e-84
sp|P49722|PSA2_MOUSE Proteasome subunit alpha type 2 (Prote... 310 3e-84
sp|P25787|PSA2_HUMAN Proteasome subunit alpha type 2 (Prote... 309 6e-84
sp|P24495|PSA2_XENLA Proteasome subunit alpha type 2 (Prote... 308 1e-83
sp|P40301|PSA2_DROME Proteasome subunit alpha type 2 (Prote... 299 6e-81
sp|Q8L4A7|PSA2B_ARATH Proteasome subunit alpha type 2-B (20... 270 3e-72
sp|O23708|PSA2A_ARATH Proteasome subunit alpha type 2-A (20... 268 8e-72
sp|Q9LSU2|PSA2_ORYSA Proteasome subunit alpha type 2 (20S p... 268 1e-71
sp|Q27488|PSA2_CAEEL Proteasome subunit alpha type 2 (Prote... 267 2e-71
>sp|O73672|PSA2_CARAU Proteasome subunit alpha type 2
Length = 234
Score = 313 bits (803), Expect = 2e-85
Identities = 160/229 (69%), Positives = 184/229 (80%)
Frame = +3
Query: 3 SFSLTTFSPSGKLVQIEYALKAVDGGAPSVGIKACNGAVLAVEKKFNSLLIDETSIKRIQ 182
SFSLTTFSPSGKLVQIEYAL AV GAPSVGIKA NG VLA EKK S+L DE S+ +I+
Sbjct: 7 SFSLTTFSPSGKLVQIEYALAAVAAGAPSVGIKASNGVVLATEKKQKSILYDEQSVHKIE 66
Query: 183 EITTNIGFVYSGLSPDYRLLVKKAIKIADDYLLSHGNLISPEQLAKSISAVMQEYTQSGG 362
IT +IG VYSG+ PDYR+LV++A K+A Y L + I QL + +++VMQEYTQSGG
Sbjct: 67 PITKHIGMVYSGMGPDYRVLVRRARKLAQQYFLVYQEPIPTGQLVQRVASVMQEYTQSGG 126
Query: 363 VRPFGVSLLIAGWDNEIDRPFLFQCDPSGTYFPWKATALGKNSGNGKSFLEKRYNDKLEL 542
VRPFGVSLLIAGWD DRP+LFQ DPSG YF WKATA+GK+ NGK+FLEKRYN+ LEL
Sbjct: 127 VRPFGVSLLIAGWDE--DRPYLFQSDPSGAYFAWKATAMGKSYVNGKTFLEKRYNEDLEL 184
Query: 543 EDAIHTSILTLKESFEGVMTEENIEVAICTDKGFRILDQSEVRDYLTAI 689
EDAIHT+ILTLKESFEG MTEENIEV IC + GFR L +EV+DYL AI
Sbjct: 185 EDAIHTAILTLKESFEGQMTEENIEVGICNEAGFRRLSPAEVKDYLAAI 233
>sp|P17220|PSA2_RAT Proteasome subunit alpha type 2 (Proteasome component C3)
(Macropain subunit C3) (Multicatalytic endopeptidase
complex subunit C3)
Length = 234
Score = 310 bits (794), Expect = 3e-84
Identities = 158/229 (68%), Positives = 182/229 (79%)
Frame = +3
Query: 3 SFSLTTFSPSGKLVQIEYALKAVDGGAPSVGIKACNGAVLAVEKKFNSLLIDETSIKRIQ 182
SFSLTTFSPSGKLVQIEYAL AV GGAPSVGIKA NG VLA EKK S+L DE S+ +++
Sbjct: 7 SFSLTTFSPSGKLVQIEYALAAVAGGAPSVGIKAANGVVLATEKKQKSILYDERSVHKVE 66
Query: 183 EITTNIGFVYSGLSPDYRLLVKKAIKIADDYLLSHGNLISPEQLAKSISAVMQEYTQSGG 362
IT +IG VYSG+ PDYR+LV +A K+A Y L + I QL + +++VMQEYTQSGG
Sbjct: 67 PITKHIGLVYSGMGPDYRVLVHRARKLAQQYYLVYQEPIPTAQLVQRVASVMQEYTQSGG 126
Query: 363 VRPFGVSLLIAGWDNEIDRPFLFQCDPSGTYFPWKATALGKNSGNGKSFLEKRYNDKLEL 542
VRPFGVSLLI GW+ RP+LFQ DPSG YF WKATA+GKN NGK+FLEKRYN+ LEL
Sbjct: 127 VRPFGVSLLICGWNE--GRPYLFQSDPSGAYFAWKATAMGKNYVNGKTFLEKRYNEDLEL 184
Query: 543 EDAIHTSILTLKESFEGVMTEENIEVAICTDKGFRILDQSEVRDYLTAI 689
EDAIHT+ILTLKESFEG MTE+NIEV IC + GFR L +EVRDYL AI
Sbjct: 185 EDAIHTAILTLKESFEGQMTEDNIEVGICNEAGFRRLTPTEVRDYLAAI 233
>sp|P49722|PSA2_MOUSE Proteasome subunit alpha type 2 (Proteasome component C3)
(Macropain subunit C3) (Multicatalytic endopeptidase
complex subunit C3)
Length = 234
Score = 310 bits (794), Expect = 3e-84
Identities = 158/229 (68%), Positives = 182/229 (79%)
Frame = +3
Query: 3 SFSLTTFSPSGKLVQIEYALKAVDGGAPSVGIKACNGAVLAVEKKFNSLLIDETSIKRIQ 182
SFSLTTFSPSGKLVQIEYAL AV GGAPSVGIKA NG VLA EKK S+L DE S+ +++
Sbjct: 7 SFSLTTFSPSGKLVQIEYALAAVAGGAPSVGIKAANGVVLATEKKQKSILYDERSVHKVE 66
Query: 183 EITTNIGFVYSGLSPDYRLLVKKAIKIADDYLLSHGNLISPEQLAKSISAVMQEYTQSGG 362
IT +IG VYSG+ PDYR+LV +A K+A Y L + I QL + +++VMQEYTQSGG
Sbjct: 67 PITKHIGLVYSGMGPDYRVLVHRARKLAQQYYLVYQEPIPTAQLVQRVASVMQEYTQSGG 126
Query: 363 VRPFGVSLLIAGWDNEIDRPFLFQCDPSGTYFPWKATALGKNSGNGKSFLEKRYNDKLEL 542
VRPFGVSLLI GW+ RP+LFQ DPSG YF WKATA+GKN NGK+FLEKRYN+ LEL
Sbjct: 127 VRPFGVSLLICGWNE--GRPYLFQSDPSGAYFAWKATAMGKNYVNGKTFLEKRYNEDLEL 184
Query: 543 EDAIHTSILTLKESFEGVMTEENIEVAICTDKGFRILDQSEVRDYLTAI 689
EDAIHT+ILTLKESFEG MTE+NIEV IC + GFR L +EVRDYL AI
Sbjct: 185 EDAIHTAILTLKESFEGQMTEDNIEVGICNEAGFRRLTPTEVRDYLAAI 233
>sp|P25787|PSA2_HUMAN Proteasome subunit alpha type 2 (Proteasome component C3)
(Macropain subunit C3) (Multicatalytic endopeptidase
complex subunit C3)
Length = 234
Score = 309 bits (791), Expect = 6e-84
Identities = 157/229 (68%), Positives = 182/229 (79%)
Frame = +3
Query: 3 SFSLTTFSPSGKLVQIEYALKAVDGGAPSVGIKACNGAVLAVEKKFNSLLIDETSIKRIQ 182
SFSLTTFSPSGKLVQIEYAL AV GGAPSVGIKA NG VLA EKK S+L DE S+ +++
Sbjct: 7 SFSLTTFSPSGKLVQIEYALAAVAGGAPSVGIKAANGVVLATEKKQKSILYDERSVHKVE 66
Query: 183 EITTNIGFVYSGLSPDYRLLVKKAIKIADDYLLSHGNLISPEQLAKSISAVMQEYTQSGG 362
IT +IG VYSG+ PDYR+LV +A K+A Y L + I QL + +++VMQEYTQSGG
Sbjct: 67 PITKHIGLVYSGMGPDYRVLVHRARKLAQQYYLVYQEPIPTAQLVQRVASVMQEYTQSGG 126
Query: 363 VRPFGVSLLIAGWDNEIDRPFLFQCDPSGTYFPWKATALGKNSGNGKSFLEKRYNDKLEL 542
VRPFGVSLLI GW+ RP+LFQ DPSG YF WKATA+GKN NGK+FLEKRYN+ LEL
Sbjct: 127 VRPFGVSLLICGWNE--GRPYLFQSDPSGAYFAWKATAMGKNYVNGKTFLEKRYNEDLEL 184
Query: 543 EDAIHTSILTLKESFEGVMTEENIEVAICTDKGFRILDQSEVRDYLTAI 689
EDAIHT+ILTLKESFEG MTE+NIEV IC + GFR L +EV+DYL AI
Sbjct: 185 EDAIHTAILTLKESFEGQMTEDNIEVGICNEAGFRRLTPTEVKDYLAAI 233
>sp|P24495|PSA2_XENLA Proteasome subunit alpha type 2 (Proteasome component C3)
(Macropain subunit C3) (Multicatalytic endopeptidase
complex subunit C3) (xC3)
Length = 234
Score = 308 bits (789), Expect = 1e-83
Identities = 157/229 (68%), Positives = 182/229 (79%)
Frame = +3
Query: 3 SFSLTTFSPSGKLVQIEYALKAVDGGAPSVGIKACNGAVLAVEKKFNSLLIDETSIKRIQ 182
SFSLTTFSPSGKLVQIEYAL AV GAPSVGIKA NG VLA EKK S+L DE S +++
Sbjct: 7 SFSLTTFSPSGKLVQIEYALAAVAAGAPSVGIKATNGVVLATEKKQKSILYDEQSAHKVE 66
Query: 183 EITTNIGFVYSGLSPDYRLLVKKAIKIADDYLLSHGNLISPEQLAKSISAVMQEYTQSGG 362
IT +IG VYSG+ PDYR+LV++A K+A Y L + I QL + +++VMQEYTQSGG
Sbjct: 67 PITKHIGMVYSGMGPDYRVLVRRARKLAQQYYLVYQEPIPTAQLVQRVASVMQEYTQSGG 126
Query: 363 VRPFGVSLLIAGWDNEIDRPFLFQCDPSGTYFPWKATALGKNSGNGKSFLEKRYNDKLEL 542
VRPFGVSLLIAGWD RP+LFQ DPSG YF WKATA+GKN NGK+FLEKRYN+ LEL
Sbjct: 127 VRPFGVSLLIAGWDE--GRPYLFQSDPSGAYFAWKATAMGKNYVNGKTFLEKRYNEDLEL 184
Query: 543 EDAIHTSILTLKESFEGVMTEENIEVAICTDKGFRILDQSEVRDYLTAI 689
EDAIHT+ILTLKESFEG MTE+NIEV IC + GF+ L +EV+DYL AI
Sbjct: 185 EDAIHTAILTLKESFEGQMTEDNIEVGICNEAGFKRLTPAEVKDYLAAI 233
>sp|P40301|PSA2_DROME Proteasome subunit alpha type 2 (Proteasome 25 kDa subunit)
(PROS-Dm25)
Length = 234
Score = 299 bits (765), Expect = 6e-81
Identities = 147/230 (63%), Positives = 180/230 (78%)
Frame = +3
Query: 3 SFSLTTFSPSGKLVQIEYALKAVDGGAPSVGIKACNGAVLAVEKKFNSLLIDETSIKRIQ 182
SFSLTTFSPSGKLVQ+EYAL AV GGAPSVGI A NG V+A E K S L ++ S+ R++
Sbjct: 7 SFSLTTFSPSGKLVQLEYALAAVSGGAPSVGIIASNGVVIATENKHKSPLYEQHSVHRVE 66
Query: 183 EITTNIGFVYSGLSPDYRLLVKKAIKIADDYLLSHGNLISPEQLAKSISAVMQEYTQSGG 362
I +IG VYSG+ PDYRLLVK+A KIA Y L++ I QL + ++ +MQEYTQSGG
Sbjct: 67 MIYNHIGMVYSGMGPDYRLLVKQARKIAQTYYLTYKEPIPVSQLVQRVATLMQEYTQSGG 126
Query: 363 VRPFGVSLLIAGWDNEIDRPFLFQCDPSGTYFPWKATALGKNSGNGKSFLEKRYNDKLEL 542
VRPFGVSLLI GWDN DRP+L+Q DPSG YF WKATA+GKN+ NGK+FLEKRY++ LEL
Sbjct: 127 VRPFGVSLLICGWDN--DRPYLYQSDPSGAYFAWKATAMGKNAVNGKTFLEKRYSEDLEL 184
Query: 543 EDAIHTSILTLKESFEGVMTEENIEVAICTDKGFRILDQSEVRDYLTAIP 692
+DA+HT+ILTLKE FEG MT +NIE+ IC GF+ LD + ++DYL +IP
Sbjct: 185 DDAVHTAILTLKEGFEGKMTADNIEIGICDQNGFQRLDPASIKDYLASIP 234
>sp|Q8L4A7|PSA2B_ARATH Proteasome subunit alpha type 2-B (20S proteasome alpha subunit
B-2)
Length = 235
Score = 270 bits (690), Expect = 3e-72
Identities = 137/230 (59%), Positives = 177/230 (76%), Gaps = 1/230 (0%)
Frame = +3
Query: 3 SFSLTTFSPSGKLVQIEYALKAVDGGAPSVGIKACNGAVLAVEKKFNSLLIDETSIKRIQ 182
SFSLTTFSPSGKLVQIE+AL AV G S+GIKA NG V+A EKK S+L+DE S+++IQ
Sbjct: 7 SFSLTTFSPSGKLVQIEHALTAVGSGQTSLGIKASNGVVIATEKKLPSILVDEASVQKIQ 66
Query: 183 EITTNIGFVYSGLSPDYRLLVKKAIKIADDYLLSHGNLISPEQLAKSISAVMQEYTQSGG 362
+T NIG VYSG+ PD+R+LV+K+ K A+ YL + I QL + + VMQE+TQSGG
Sbjct: 67 HLTPNIGTVYSGMGPDFRVLVRKSRKQAEQYLRLYKEPIPVTQLVRETATVMQEFTQSGG 126
Query: 363 VRPFGVSLLIAGWDNEIDRPFLFQCDPSGTYFPWKATALGKNSGNGKSFLEKRYNDKLEL 542
VRPFGVSLL+AG+D++ P L+Q DPSG+YF WKA+A+GKN N K+FLEKRY + +EL
Sbjct: 127 VRPFGVSLLVAGYDDK--GPQLYQVDPSGSYFSWKASAMGKNVSNAKTFLEKRYTEDMEL 184
Query: 543 EDAIHTSILTLKESFEGVMTEENIEVA-ICTDKGFRILDQSEVRDYLTAI 689
+DAIHT+ILTLKE FEG ++ +NIE+ I TDK FR+L +E+ DYL +
Sbjct: 185 DDAIHTAILTLKEGFEGEISSKNIEIGKIGTDKVFRVLTPAEIDDYLAEV 234
>sp|O23708|PSA2A_ARATH Proteasome subunit alpha type 2-A (20S proteasome alpha subunit B)
(Proteasome component 3)
Length = 235
Score = 268 bits (686), Expect = 8e-72
Identities = 136/230 (59%), Positives = 176/230 (76%), Gaps = 1/230 (0%)
Frame = +3
Query: 3 SFSLTTFSPSGKLVQIEYALKAVDGGAPSVGIKACNGAVLAVEKKFNSLLIDETSIKRIQ 182
SFSLTTFSPSGKLVQIE+AL AV G S+GIKA NG V+A EKK S+L+DE S+++IQ
Sbjct: 7 SFSLTTFSPSGKLVQIEHALTAVGSGQTSLGIKASNGVVIATEKKLPSILVDEASVQKIQ 66
Query: 183 EITTNIGFVYSGLSPDYRLLVKKAIKIADDYLLSHGNLISPEQLAKSISAVMQEYTQSGG 362
+T NIG VYSG+ PD+R+LV+K+ K A+ YL + I QL + + VMQE+TQSGG
Sbjct: 67 HLTPNIGVVYSGMGPDFRVLVRKSRKQAEQYLRLYKEPIPVTQLVRETATVMQEFTQSGG 126
Query: 363 VRPFGVSLLIAGWDNEIDRPFLFQCDPSGTYFPWKATALGKNSGNGKSFLEKRYNDKLEL 542
VRPFGVSLL+AG+D++ P L+Q DPSG+YF WKA+A+GKN N K+FLEKRY + +EL
Sbjct: 127 VRPFGVSLLVAGYDDK--GPQLYQVDPSGSYFSWKASAMGKNVSNAKTFLEKRYTEDMEL 184
Query: 543 EDAIHTSILTLKESFEGVMTEENIEVA-ICTDKGFRILDQSEVRDYLTAI 689
+DAIHT+ILTLKE FEG ++ +NIE+ I DK FR+L +E+ DYL +
Sbjct: 185 DDAIHTAILTLKEGFEGEISSKNIEIGKIGADKVFRVLTPAEIDDYLAEV 234
>sp|Q9LSU2|PSA2_ORYSA Proteasome subunit alpha type 2 (20S proteasome alpha subunit B)
(20S proteasome subunit alpha-2)
Length = 235
Score = 268 bits (685), Expect = 1e-71
Identities = 134/230 (58%), Positives = 177/230 (76%), Gaps = 1/230 (0%)
Frame = +3
Query: 3 SFSLTTFSPSGKLVQIEYALKAVDGGAPSVGIKACNGAVLAVEKKFNSLLIDETSIKRIQ 182
SFSLTTFSPSGKLVQIE+AL AV G S+GIKA NG V+A EKK S+L+DETS+++IQ
Sbjct: 7 SFSLTTFSPSGKLVQIEHALTAVGSGQTSLGIKAANGVVIATEKKLPSILVDETSVQKIQ 66
Query: 183 EITTNIGFVYSGLSPDYRLLVKKAIKIADDYLLSHGNLISPEQLAKSISAVMQEYTQSGG 362
+T NIG VYSG+ PD+R+LV+K+ K A Y + I QL + +AVMQE+TQSGG
Sbjct: 67 SLTPNIGVVYSGMGPDFRVLVRKSRKQAQQYYRLYKETIPVTQLVRETAAVMQEFTQSGG 126
Query: 363 VRPFGVSLLIAGWDNEIDRPFLFQCDPSGTYFPWKATALGKNSGNGKSFLEKRYNDKLEL 542
VRPFGVSLLIAG+D+ + P L+Q DPSG+YF WKA+A+GKN N K+FLEKRY + +EL
Sbjct: 127 VRPFGVSLLIAGYDD--NGPQLYQVDPSGSYFSWKASAMGKNVSNAKTFLEKRYTEDMEL 184
Query: 543 EDAIHTSILTLKESFEGVMTEENIEVAIC-TDKGFRILDQSEVRDYLTAI 689
+DAIHT+ILTLKE +EG ++ NIE+ I +D+ F++L +E++D+L +
Sbjct: 185 DDAIHTAILTLKEGYEGQISANNIEIGIIRSDREFKVLSPAEIKDFLEEV 234
>sp|Q27488|PSA2_CAEEL Proteasome subunit alpha type 2 (Proteasome subunit alpha 2)
Length = 231
Score = 267 bits (682), Expect = 2e-71
Identities = 135/225 (60%), Positives = 169/225 (75%)
Frame = +3
Query: 6 FSLTTFSPSGKLVQIEYALKAVDGGAPSVGIKACNGAVLAVEKKFNSLLIDETSIKRIQE 185
FSLTTFSPSGKL+QIEYAL AV G PSVG++A +G VLA E S+L D+ ++++
Sbjct: 7 FSLTTFSPSGKLMQIEYALNAVKNGQPSVGLRAKDGVVLATEN-VGSVLTDDQP--KVEQ 63
Query: 186 ITTNIGFVYSGLSPDYRLLVKKAIKIADDYLLSHGNLISPEQLAKSISAVMQEYTQSGGV 365
I+ +IG VYSG+ PD+R+LVKKA KIA +Y + +G + QL I+AVMQEYTQSGGV
Sbjct: 64 ISKHIGCVYSGMGPDFRILVKKARKIAMEYEMMYGEEMPTIQLVTDIAAVMQEYTQSGGV 123
Query: 366 RPFGVSLLIAGWDNEIDRPFLFQCDPSGTYFPWKATALGKNSGNGKSFLEKRYNDKLELE 545
RPFG SLLIAGWD RP LFQCDPSG YF WKATALGKN N K+FLEKR+++ LEL+
Sbjct: 124 RPFGASLLIAGWDKNPGRPLLFQCDPSGAYFAWKATALGKNDVNAKTFLEKRFSEALELD 183
Query: 546 DAIHTSILTLKESFEGVMTEENIEVAICTDKGFRILDQSEVRDYL 680
D IHT++LTL+ESF+ M E N+EVA+C GF L + +V D+L
Sbjct: 184 DGIHTALLTLRESFDVGMNENNVEVAVCNSTGFHRLTKQQVHDHL 228
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 82,455,857
Number of Sequences: 369166
Number of extensions: 1645837
Number of successful extensions: 4828
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 4528
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4645
length of database: 68,354,980
effective HSP length: 108
effective length of database: 48,403,600
effective search space used: 6486082400
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)