Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= DrC_01211 (742 letters) Database: Non-redundant SwissProt sequences 184,735 sequences; 68,354,980 total letters Score E Sequences producing significant alignments: (bits) Value sp|O94312|YH57_SCHPO PWWP domain protein C215.07c 33 1.0 sp|P25588|MRC1_YEAST Mediator of replication checkpoint pro... 32 2.3 sp|P38742|YHC3_YEAST Hypothetical 130.0 kDa protein in SNF6... 31 4.0 sp|P45978|SCD6_YEAST Protein SCD6 31 4.0 sp|O94466|RGA7_SCHPO Probable Rho-GTPase-activating protein 7 31 4.0 sp|Q62315|JARD2_MOUSE Jumonji protein (Jumonji/ARID domain-... 30 8.8 sp|P16237|HMDH_SCHMA 3-hydroxy-3-methylglutaryl-coenzyme A ... 30 8.8 sp|Q9UU99|YJX4_SCHPO Protein C23B6.04c in chromosome III 30 8.8 sp|P78022|RPOD_MYCPN RNA polymerase sigma factor rpoD (Sigm... 30 8.8 sp|Q8NEZ4|MLL3_HUMAN Myeloid/lymphoid or mixed-lineage leuk... 30 8.8
>sp|O94312|YH57_SCHPO PWWP domain protein C215.07c Length = 568 Score = 32.7 bits (73), Expect = 1.0 Identities = 22/84 (26%), Positives = 40/84 (47%), Gaps = 12/84 (14%) Frame = +3 Query: 195 FGVGRSSLRKGSDS--PINSEVLTR--NSPSPT--------KTVKFNPTLHCKTIPNSSN 338 F + L GSDS P+ SE +++ P P K + P L ++P+S + Sbjct: 169 FFPNKEYLWTGSDSLTPLTSEAISQFLEKPKPKTASLIKAYKMAQSTPDLDSLSVPSSES 228 Query: 339 RNKDIKTKSRKPKPSPNKDDFNDS 410 + ++ +PSP ++D+ND+ Sbjct: 229 EVSEEESDQEMSEPSPIEEDYNDT 252
>sp|P25588|MRC1_YEAST Mediator of replication checkpoint protein 1 (DNA replication checkpoint mediator MRC1) Length = 1096 Score = 31.6 bits (70), Expect = 2.3 Identities = 17/56 (30%), Positives = 26/56 (46%) Frame = +3 Query: 243 NSEVLTRNSPSPTKTVKFNPTLHCKTIPNSSNRNKDIKTKSRKPKPSPNKDDFNDS 410 N E P PTK + +SSN + DIK ++ PKP N D+ +++ Sbjct: 310 NVEYKKPQKPIPTKKFFSKESFLADFDDSSSNEDDDIKLENAHPKPVQNDDELHEN 365
>sp|P38742|YHC3_YEAST Hypothetical 130.0 kDa protein in SNF6-SPO11 intergenic region Length = 1146 Score = 30.8 bits (68), Expect = 4.0 Identities = 23/78 (29%), Positives = 36/78 (46%), Gaps = 2/78 (2%) Frame = +3 Query: 249 EVLTRNSPSPTKTVKFNPTLHCKTIPNSSNRNKDIKTKSRKPKPSPNKDD--FNDSLFMT 422 +++ PS T + NPT H N +N NK+ T NK++ FN T Sbjct: 24 QIVYHYPPSNTAFLTNNPTKHQHLYGNHANLNKNTST---------NKEEKLFNSGSTKT 74 Query: 423 SSNIGLVEAHESFISECT 476 +S I L E+ +S+ + T Sbjct: 75 ASQIALNESAKSYNTAIT 92
>sp|P45978|SCD6_YEAST Protein SCD6 Length = 349 Score = 30.8 bits (68), Expect = 4.0 Identities = 35/163 (21%), Positives = 69/163 (42%), Gaps = 7/163 (4%) Frame = +3 Query: 162 PSDCEAPPQAQFG--VGRSSLRKGSDSPINSEVLTRNSPSPTKTVKFNPTLHCKTIPNSS 335 P ++PPQAQ V + +S + + V +PT T +++ K+ P + Sbjct: 100 PQQAQSPPQAQAQAHVQTNPQVPKPESNVPAAVAGYGVYTPTSTETATASMNDKSTPQDT 159 Query: 336 NRNKDIKTKSR----KPKPSPNKDDFNDSLFMTSSNIGLVEAHESFISECTHLIRFQMSL 503 N N + + + +PK NK+ ++ ++ N + +E F + + + Sbjct: 160 NVNSQSRERGKNGENEPKYQRNKNRSSNRPPQSNRNFKVDIPNEDFDFQSNNAKFTKGDS 219 Query: 504 MENFREKKISSRSYQRD-LIEIIEKQKRSLLDFHLTVTNCPTN 629 + +EK++ S +++D E +K S D T T TN Sbjct: 220 TDVEKEKELESAVHKQDESDEQFYNKKSSFFDTISTSTETNTN 262
>sp|O94466|RGA7_SCHPO Probable Rho-GTPase-activating protein 7 Length = 695 Score = 30.8 bits (68), Expect = 4.0 Identities = 28/95 (29%), Positives = 42/95 (44%), Gaps = 12/95 (12%) Frame = +3 Query: 183 PQAQFGVGRSSLRKGSDSPINSEV-LTRNSPSPTKTVKF------NPTLHCKTIPNSSNR 341 P + +G G S+ + ++ P+N + +T PSP + NP++ PNSS Sbjct: 336 PPSSYGTGSSAGK--TNPPVNPTIKVTAAIPSPLQNTNPAPSTFPNPSVASPAFPNSSTS 393 Query: 342 NKDIKTKSRKP-----KPSPNKDDFNDSLFMTSSN 431 N S P KPS +D N S +SSN Sbjct: 394 NPSTAPASASPLASTLKPS-TANDTNGSSSSSSSN 427
>sp|Q62315|JARD2_MOUSE Jumonji protein (Jumonji/ARID domain-containing protein 2) Length = 1234 Score = 29.6 bits (65), Expect = 8.8 Identities = 23/64 (35%), Positives = 36/64 (56%), Gaps = 2/64 (3%) Frame = +3 Query: 198 GVGR-SSLRKGSDSPINSEVLTRNSPSPTKTVKFNPTLHCKTIPNSSNRNKDIK-TKSRK 371 GV R SSL G++S ++ + PSP+KTVK+ T+ T+ + + + +K TK Sbjct: 308 GVTRMSSLGAGTNS---AKKIREVRPSPSKTVKYTATVTKGTVTYTKAKRELVKETKPNH 364 Query: 372 PKPS 383 KPS Sbjct: 365 HKPS 368
>sp|P16237|HMDH_SCHMA 3-hydroxy-3-methylglutaryl-coenzyme A reductase (HMG-CoA reductase) Length = 948 Score = 29.6 bits (65), Expect = 8.8 Identities = 17/56 (30%), Positives = 27/56 (48%) Frame = +3 Query: 231 DSPINSEVLTRNSPSPTKTVKFNPTLHCKTIPNSSNRNKDIKTKSRKPKPSPNKDD 398 + PINS++ N P +T+ + +P S + DI +SRK +KDD Sbjct: 369 NKPINSQLRNLNIPKIKETLISDQVKQSPVLPKFSKKLNDIPLQSRKRIYCLHKDD 424
>sp|Q9UU99|YJX4_SCHPO Protein C23B6.04c in chromosome III Length = 1008 Score = 29.6 bits (65), Expect = 8.8 Identities = 16/42 (38%), Positives = 20/42 (47%) Frame = +3 Query: 255 LTRNSPSPTKTVKFNPTLHCKTIPNSSNRNKDIKTKSRKPKP 380 LT S SPT T N KT+ NS++ K + PKP Sbjct: 884 LTNRSSSPTVTPTVNTDRQPKTLTNSADELSPQKRRVENPKP 925
>sp|P78022|RPOD_MYCPN RNA polymerase sigma factor rpoD (Sigma-A) Length = 499 Score = 29.6 bits (65), Expect = 8.8 Identities = 20/87 (22%), Positives = 41/87 (47%) Frame = +3 Query: 315 KTIPNSSNRNKDIKTKSRKPKPSPNKDDFNDSLFMTSSNIGLVEAHESFISECTHLIRFQ 494 KT+ + + K + RKPK +P K+ N LF G +++H + +I Sbjct: 65 KTLQENKESDVPKKRRGRKPKHAPLKEKNNLKLFDILE--GSLKSHTE-NDDTNKVISLL 121 Query: 495 MSLMENFREKKISSRSYQRDLIEIIEK 575 + + E +KK ++ +D++ ++ K Sbjct: 122 VEVWEKKNKKKDNNSLSNKDIVNVLSK 148
>sp|Q8NEZ4|MLL3_HUMAN Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein) Length = 4911 Score = 29.6 bits (65), Expect = 8.8 Identities = 23/85 (27%), Positives = 42/85 (49%), Gaps = 9/85 (10%) Frame = +3 Query: 186 QAQFGVGRSSLRKGSDSPINSEVLTRNSPSP-----TKTVKFNPTLHCKTIPNS----SN 338 Q QFG ++ GSD+P +S + + +P P + F+ L K P++ S+ Sbjct: 1785 QQQFGSQHLLVQSGSDTP-SSGIQSPLTPQPGNGNMSPAQSFHKELFTKQPPSTPTSTSS 1843 Query: 339 RNKDIKTKSRKPKPSPNKDDFNDSL 413 + +K ++ P P+P++ DSL Sbjct: 1844 DDVFVKPQAPPPPPAPSRIPIQDSL 1868
Database: Non-redundant SwissProt sequences Posted date: Dec 6, 2005 7:40 AM Number of letters in database: 68,354,980 Number of sequences in database: 184,735 Database: swissprot.01 Posted date: Dec 6, 2005 8:18 AM Number of letters in database: 66,202,850 Number of sequences in database: 184,431 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 77,472,688 Number of Sequences: 369166 Number of extensions: 1468956 Number of successful extensions: 3982 Number of sequences better than 10.0: 10 Number of HSP's better than 10.0 without gapping: 3760 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 3973 length of database: 68,354,980 effective HSP length: 108 effective length of database: 48,403,600 effective search space used: 6679696800 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)