Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_001_O12
(742 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|O94312|YH57_SCHPO PWWP domain protein C215.07c 33 1.0
sp|P25588|MRC1_YEAST Mediator of replication checkpoint pro... 32 2.3
sp|P38742|YHC3_YEAST Hypothetical 130.0 kDa protein in SNF6... 31 4.0
sp|P45978|SCD6_YEAST Protein SCD6 31 4.0
sp|O94466|RGA7_SCHPO Probable Rho-GTPase-activating protein 7 31 4.0
sp|Q62315|JARD2_MOUSE Jumonji protein (Jumonji/ARID domain-... 30 8.8
sp|P16237|HMDH_SCHMA 3-hydroxy-3-methylglutaryl-coenzyme A ... 30 8.8
sp|Q9UU99|YJX4_SCHPO Protein C23B6.04c in chromosome III 30 8.8
sp|P78022|RPOD_MYCPN RNA polymerase sigma factor rpoD (Sigm... 30 8.8
sp|Q8NEZ4|MLL3_HUMAN Myeloid/lymphoid or mixed-lineage leuk... 30 8.8
>sp|O94312|YH57_SCHPO PWWP domain protein C215.07c
Length = 568
Score = 32.7 bits (73), Expect = 1.0
Identities = 22/84 (26%), Positives = 40/84 (47%), Gaps = 12/84 (14%)
Frame = +3
Query: 195 FGVGRSSLRKGSDS--PINSEVLTR--NSPSPT--------KTVKFNPTLHCKTIPNSSN 338
F + L GSDS P+ SE +++ P P K + P L ++P+S +
Sbjct: 169 FFPNKEYLWTGSDSLTPLTSEAISQFLEKPKPKTASLIKAYKMAQSTPDLDSLSVPSSES 228
Query: 339 RNKDIKTKSRKPKPSPNKDDFNDS 410
+ ++ +PSP ++D+ND+
Sbjct: 229 EVSEEESDQEMSEPSPIEEDYNDT 252
>sp|P25588|MRC1_YEAST Mediator of replication checkpoint protein 1 (DNA replication
checkpoint mediator MRC1)
Length = 1096
Score = 31.6 bits (70), Expect = 2.3
Identities = 17/56 (30%), Positives = 26/56 (46%)
Frame = +3
Query: 243 NSEVLTRNSPSPTKTVKFNPTLHCKTIPNSSNRNKDIKTKSRKPKPSPNKDDFNDS 410
N E P PTK + +SSN + DIK ++ PKP N D+ +++
Sbjct: 310 NVEYKKPQKPIPTKKFFSKESFLADFDDSSSNEDDDIKLENAHPKPVQNDDELHEN 365
>sp|P38742|YHC3_YEAST Hypothetical 130.0 kDa protein in SNF6-SPO11 intergenic region
Length = 1146
Score = 30.8 bits (68), Expect = 4.0
Identities = 23/78 (29%), Positives = 36/78 (46%), Gaps = 2/78 (2%)
Frame = +3
Query: 249 EVLTRNSPSPTKTVKFNPTLHCKTIPNSSNRNKDIKTKSRKPKPSPNKDD--FNDSLFMT 422
+++ PS T + NPT H N +N NK+ T NK++ FN T
Sbjct: 24 QIVYHYPPSNTAFLTNNPTKHQHLYGNHANLNKNTST---------NKEEKLFNSGSTKT 74
Query: 423 SSNIGLVEAHESFISECT 476
+S I L E+ +S+ + T
Sbjct: 75 ASQIALNESAKSYNTAIT 92
>sp|P45978|SCD6_YEAST Protein SCD6
Length = 349
Score = 30.8 bits (68), Expect = 4.0
Identities = 35/163 (21%), Positives = 69/163 (42%), Gaps = 7/163 (4%)
Frame = +3
Query: 162 PSDCEAPPQAQFG--VGRSSLRKGSDSPINSEVLTRNSPSPTKTVKFNPTLHCKTIPNSS 335
P ++PPQAQ V + +S + + V +PT T +++ K+ P +
Sbjct: 100 PQQAQSPPQAQAQAHVQTNPQVPKPESNVPAAVAGYGVYTPTSTETATASMNDKSTPQDT 159
Query: 336 NRNKDIKTKSR----KPKPSPNKDDFNDSLFMTSSNIGLVEAHESFISECTHLIRFQMSL 503
N N + + + +PK NK+ ++ ++ N + +E F + + +
Sbjct: 160 NVNSQSRERGKNGENEPKYQRNKNRSSNRPPQSNRNFKVDIPNEDFDFQSNNAKFTKGDS 219
Query: 504 MENFREKKISSRSYQRD-LIEIIEKQKRSLLDFHLTVTNCPTN 629
+ +EK++ S +++D E +K S D T T TN
Sbjct: 220 TDVEKEKELESAVHKQDESDEQFYNKKSSFFDTISTSTETNTN 262
>sp|O94466|RGA7_SCHPO Probable Rho-GTPase-activating protein 7
Length = 695
Score = 30.8 bits (68), Expect = 4.0
Identities = 28/95 (29%), Positives = 42/95 (44%), Gaps = 12/95 (12%)
Frame = +3
Query: 183 PQAQFGVGRSSLRKGSDSPINSEV-LTRNSPSPTKTVKF------NPTLHCKTIPNSSNR 341
P + +G G S+ + ++ P+N + +T PSP + NP++ PNSS
Sbjct: 336 PPSSYGTGSSAGK--TNPPVNPTIKVTAAIPSPLQNTNPAPSTFPNPSVASPAFPNSSTS 393
Query: 342 NKDIKTKSRKP-----KPSPNKDDFNDSLFMTSSN 431
N S P KPS +D N S +SSN
Sbjct: 394 NPSTAPASASPLASTLKPS-TANDTNGSSSSSSSN 427
>sp|Q62315|JARD2_MOUSE Jumonji protein (Jumonji/ARID domain-containing protein 2)
Length = 1234
Score = 29.6 bits (65), Expect = 8.8
Identities = 23/64 (35%), Positives = 36/64 (56%), Gaps = 2/64 (3%)
Frame = +3
Query: 198 GVGR-SSLRKGSDSPINSEVLTRNSPSPTKTVKFNPTLHCKTIPNSSNRNKDIK-TKSRK 371
GV R SSL G++S ++ + PSP+KTVK+ T+ T+ + + + +K TK
Sbjct: 308 GVTRMSSLGAGTNS---AKKIREVRPSPSKTVKYTATVTKGTVTYTKAKRELVKETKPNH 364
Query: 372 PKPS 383
KPS
Sbjct: 365 HKPS 368
>sp|P16237|HMDH_SCHMA 3-hydroxy-3-methylglutaryl-coenzyme A reductase (HMG-CoA reductase)
Length = 948
Score = 29.6 bits (65), Expect = 8.8
Identities = 17/56 (30%), Positives = 27/56 (48%)
Frame = +3
Query: 231 DSPINSEVLTRNSPSPTKTVKFNPTLHCKTIPNSSNRNKDIKTKSRKPKPSPNKDD 398
+ PINS++ N P +T+ + +P S + DI +SRK +KDD
Sbjct: 369 NKPINSQLRNLNIPKIKETLISDQVKQSPVLPKFSKKLNDIPLQSRKRIYCLHKDD 424
>sp|Q9UU99|YJX4_SCHPO Protein C23B6.04c in chromosome III
Length = 1008
Score = 29.6 bits (65), Expect = 8.8
Identities = 16/42 (38%), Positives = 20/42 (47%)
Frame = +3
Query: 255 LTRNSPSPTKTVKFNPTLHCKTIPNSSNRNKDIKTKSRKPKP 380
LT S SPT T N KT+ NS++ K + PKP
Sbjct: 884 LTNRSSSPTVTPTVNTDRQPKTLTNSADELSPQKRRVENPKP 925
>sp|P78022|RPOD_MYCPN RNA polymerase sigma factor rpoD (Sigma-A)
Length = 499
Score = 29.6 bits (65), Expect = 8.8
Identities = 20/87 (22%), Positives = 41/87 (47%)
Frame = +3
Query: 315 KTIPNSSNRNKDIKTKSRKPKPSPNKDDFNDSLFMTSSNIGLVEAHESFISECTHLIRFQ 494
KT+ + + K + RKPK +P K+ N LF G +++H + +I
Sbjct: 65 KTLQENKESDVPKKRRGRKPKHAPLKEKNNLKLFDILE--GSLKSHTE-NDDTNKVISLL 121
Query: 495 MSLMENFREKKISSRSYQRDLIEIIEK 575
+ + E +KK ++ +D++ ++ K
Sbjct: 122 VEVWEKKNKKKDNNSLSNKDIVNVLSK 148
>sp|Q8NEZ4|MLL3_HUMAN Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog
(Histone-lysine N-methyltransferase, H3 lysine-4 specific
MLL3) (Homologous to ALR protein)
Length = 4911
Score = 29.6 bits (65), Expect = 8.8
Identities = 23/85 (27%), Positives = 42/85 (49%), Gaps = 9/85 (10%)
Frame = +3
Query: 186 QAQFGVGRSSLRKGSDSPINSEVLTRNSPSP-----TKTVKFNPTLHCKTIPNS----SN 338
Q QFG ++ GSD+P +S + + +P P + F+ L K P++ S+
Sbjct: 1785 QQQFGSQHLLVQSGSDTP-SSGIQSPLTPQPGNGNMSPAQSFHKELFTKQPPSTPTSTSS 1843
Query: 339 RNKDIKTKSRKPKPSPNKDDFNDSL 413
+ +K ++ P P+P++ DSL
Sbjct: 1844 DDVFVKPQAPPPPPAPSRIPIQDSL 1868
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 77,472,688
Number of Sequences: 369166
Number of extensions: 1468956
Number of successful extensions: 3982
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 3760
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3973
length of database: 68,354,980
effective HSP length: 108
effective length of database: 48,403,600
effective search space used: 6679696800
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)