Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= DrC_00997 (868 letters) Database: Non-redundant SwissProt sequences 184,735 sequences; 68,354,980 total letters Score E Sequences producing significant alignments: (bits) Value sp|Q27655|ENO_FASHE Enolase (2-phosphoglycerate dehydratase... 367 e-101 sp|P33676|ENO_SCHJA Enolase (2-phosphoglycerate dehydratase... 365 e-100 sp|O02654|ENO_LOLPE Enolase (2-phosphoglycerate dehydratase... 355 7e-98 sp|Q27527|ENO_CAEEL Enolase (2-phosphoglycerate dehydratase... 349 5e-96 sp|Q27877|ENO_SCHMA Enolase (2-phosphoglycerate dehydratase... 348 1e-95 sp|P09104|ENOG_HUMAN Gamma-enolase (2-phospho-D-glycerate h... 346 5e-95 sp|P17183|ENOG_MOUSE Gamma-enolase (2-phospho-D-glycerate h... 345 9e-95 sp|P07323|ENOG_RAT Gamma-enolase (2-phospho-D-glycerate hyd... 344 2e-94 sp|Q9PVK2|ENOA_ALLMI Alpha-enolase (2-phospho-D-glycerate h... 344 2e-94 sp|P19140|ENOA_ANAPL Alpha-enolase (2-phospho-D-glycerate h... 343 3e-94
>sp|Q27655|ENO_FASHE Enolase (2-phosphoglycerate dehydratase) (2-phospho-D-glycerate hydro-lyase) Length = 431 Score = 367 bits (941), Expect = e-101 Identities = 179/226 (79%), Positives = 192/226 (84%) Frame = +3 Query: 3 VGDEGGFAPNILDNFEGLELLKVAIEAAGYTGKIKIGMDVAASEFYKEGKYDLDFKNPHS 182 VGDEGGFAP+I DN EGLELL+ AI+ AGYTGK+ I MD AASEFYKEGKYDLDFKNP S Sbjct: 206 VGDEGGFAPSIQDNLEGLELLRTAIDKAGYTGKVXIAMDCAASEFYKEGKYDLDFKNPKS 265 Query: 183 DKSKWLTSSELAAVYTDMIHKYPIVSIEDPFDQDDWSAWTDFSGKAGIQIVGDDLTVTNP 362 S W+TS +A VY M+ YPIVSIEDPFDQDDW AWT +G+ IQIVGDDLTVTNP Sbjct: 266 QASSWITSDAMADVYKKMMSTYPIVSIEDPFDQDDWPAWTKLTGECKIQIVGDDLTVTNP 325 Query: 363 TRVQKGIDVKACNCLLLKVNQIGSVTESIQACKMSQNAGWGVMVSHRSGETEDNTIADLV 542 RVQK ID KACNCLLLKVNQIGSV+ESI+ACKM+Q AGWGVMVSHRSGETEDN IADLV Sbjct: 326 LRVQKAIDQKACNCLLLKVNQIGSVSESIKACKMAQEAGWGVMVSHRSGETEDNFIADLV 385 Query: 543 VGLRTGQIKTGAPCRSERLAKYNQLLRIEEELGAKAAYAGEKFHHP 680 VGLRTGQIKTGAPCRSERLAKYNQLLRIEE+LG A YAGE F P Sbjct: 386 VGLRTGQIKTGAPCRSERLAKYNQLLRIEEDLGGAAKYAGENFRRP 431
>sp|P33676|ENO_SCHJA Enolase (2-phosphoglycerate dehydratase) (2-phospho-D-glycerate hydro-lyase) Length = 434 Score = 365 bits (936), Expect = e-100 Identities = 175/226 (77%), Positives = 195/226 (86%) Frame = +3 Query: 3 VGDEGGFAPNILDNFEGLELLKVAIEAAGYTGKIKIGMDVAASEFYKEGKYDLDFKNPHS 182 VGDEGGFAPNI DN +GL+LL+ AI+ AGYTGK++IGMD AASE+YK+GKYDLDFKNP S Sbjct: 207 VGDEGGFAPNIQDNMKGLQLLEEAIKIAGYTGKVEIGMDCAASEYYKKGKYDLDFKNPQS 266 Query: 183 DKSKWLTSSELAAVYTDMIHKYPIVSIEDPFDQDDWSAWTDFSGKAGIQIVGDDLTVTNP 362 +S WL+ E+A VY +MI KYPIVSIEDPFDQDDW AW + IQIVGDDLTVTNP Sbjct: 267 AESHWLSPDEMANVYKEMIQKYPIVSIEDPFDQDDWDAWPKLTASTNIQIVGDDLTVTNP 326 Query: 363 TRVQKGIDVKACNCLLLKVNQIGSVTESIQACKMSQNAGWGVMVSHRSGETEDNTIADLV 542 R++K I VKACNCLLLKVNQIGS+TESI+ACKM+Q AGWGVMVSHRSGETEDN IADLV Sbjct: 327 KRIEKAIKVKACNCLLLKVNQIGSITESIEACKMAQKAGWGVMVSHRSGETEDNFIADLV 386 Query: 543 VGLRTGQIKTGAPCRSERLAKYNQLLRIEEELGAKAAYAGEKFHHP 680 VGL TGQIKTGAPCRSERLAKYNQLLRIEEELG+ A YAG+ F HP Sbjct: 387 VGLCTGQIKTGAPCRSERLAKYNQLLRIEEELGSTAKYAGKHFRHP 432
>sp|O02654|ENO_LOLPE Enolase (2-phosphoglycerate dehydratase) (2-phospho-D-glycerate hydro-lyase) Length = 434 Score = 355 bits (912), Expect = 7e-98 Identities = 178/226 (78%), Positives = 193/226 (85%) Frame = +3 Query: 3 VGDEGGFAPNILDNFEGLELLKVAIEAAGYTGKIKIGMDVAASEFYKEGKYDLDFKNPHS 182 VGDEGGFAPNILDN EGLELLK AI AGYT +I+IGMDVAASEF KE KYDLDFKNP S Sbjct: 207 VGDEGGFAPNILDNKEGLELLKTAIANAGYTAEIEIGMDVAASEFCKEKKYDLDFKNPDS 266 Query: 183 DKSKWLTSSELAAVYTDMIHKYPIVSIEDPFDQDDWSAWTDFSGKAGIQIVGDDLTVTNP 362 + + WLTS +LA VY D + YP+VSIEDPFDQDDW A+T + IQIVGDDL VTNP Sbjct: 267 NPNDWLTSDQLADVYKDFVKNYPVVSIEDPFDQDDWEAYTKMTKDMDIQIVGDDLLVTNP 326 Query: 363 TRVQKGIDVKACNCLLLKVNQIGSVTESIQACKMSQNAGWGVMVSHRSGETEDNTIADLV 542 RVQKGID+KA N LLLKVNQIGSVTESIQACKMSQ+AGWGVMVSHRSGETED IADLV Sbjct: 327 KRVQKGIDLKAANALLLKVNQIGSVTESIQACKMSQDAGWGVMVSHRSGETEDTFIADLV 386 Query: 543 VGLRTGQIKTGAPCRSERLAKYNQLLRIEEELGAKAAYAGEKFHHP 680 VGL TGQIKTGAPCRSERLAKYNQ+LRIEEELG KA +AG+KF +P Sbjct: 387 VGLCTGQIKTGAPCRSERLAKYNQILRIEEELGDKAVFAGKKFRNP 432
>sp|Q27527|ENO_CAEEL Enolase (2-phosphoglycerate dehydratase) (2-phospho-D-glycerate hydro-lyase) Length = 434 Score = 349 bits (896), Expect = 5e-96 Identities = 170/226 (75%), Positives = 186/226 (82%) Frame = +3 Query: 3 VGDEGGFAPNILDNFEGLELLKVAIEAAGYTGKIKIGMDVAASEFYKEGKYDLDFKNPHS 182 VGDEGGFAPNI DN EGL+LL AI+ AGYTGKI IGMDVAASEF+K+GKYDLDFKNP S Sbjct: 207 VGDEGGFAPNIQDNKEGLDLLNTAIDKAGYTGKISIGMDVAASEFFKDGKYDLDFKNPAS 266 Query: 183 DKSKWLTSSELAAVYTDMIHKYPIVSIEDPFDQDDWSAWTDFSGKAGIQIVGDDLTVTNP 362 D SKWL+ +L +Y I +YP+VSIED FDQDDW W F G IQ+VGDDLTVTNP Sbjct: 267 DSSKWLSGEQLTELYQSFIKEYPVVSIEDAFDQDDWDNWGKFHGATSIQLVGDDLTVTNP 326 Query: 363 TRVQKGIDVKACNCLLLKVNQIGSVTESIQACKMSQNAGWGVMVSHRSGETEDNTIADLV 542 R+Q ID K+CNCLLLKVNQIGSVTESI+A K+S+ GWGVMVSHRSGETED IADLV Sbjct: 327 KRIQTAIDKKSCNCLLLKVNQIGSVTESIEAAKLSRANGWGVMVSHRSGETEDTFIADLV 386 Query: 543 VGLRTGQIKTGAPCRSERLAKYNQLLRIEEELGAKAAYAGEKFHHP 680 VGL TGQIKTGAPCRSERLAKYNQLLRIEEELGA A YAG F +P Sbjct: 387 VGLATGQIKTGAPCRSERLAKYNQLLRIEEELGADAVYAGHNFRNP 432
>sp|Q27877|ENO_SCHMA Enolase (2-phosphoglycerate dehydratase) (2-phospho-D-glycerate hydro-lyase) Length = 434 Score = 348 bits (893), Expect = 1e-95 Identities = 166/226 (73%), Positives = 190/226 (84%) Frame = +3 Query: 3 VGDEGGFAPNILDNFEGLELLKVAIEAAGYTGKIKIGMDVAASEFYKEGKYDLDFKNPHS 182 VGDEGGFAPNI DN +GL+LL+ AI+ AGYTGK++IGMD AASEF+K GKYDLDFKNPHS Sbjct: 207 VGDEGGFAPNIQDNMKGLQLLEEAIKIAGYTGKVEIGMDCAASEFHKNGKYDLDFKNPHS 266 Query: 183 DKSKWLTSSELAAVYTDMIHKYPIVSIEDPFDQDDWSAWTDFSGKAGIQIVGDDLTVTNP 362 +S WL+ +A +Y MI K+PIVSIEDPFDQDDW W + IQIVGDDLTVTNP Sbjct: 267 AESTWLSPDAMANMYKQMISKFPIVSIEDPFDQDDWETWPKLTSSTNIQIVGDDLTVTNP 326 Query: 363 TRVQKGIDVKACNCLLLKVNQIGSVTESIQACKMSQNAGWGVMVSHRSGETEDNTIADLV 542 R+++ I KACNCLLLKVNQIGS+TESI+ACK++Q++GWGVMVSHRSGETED IADLV Sbjct: 327 KRIKQAIASKACNCLLLKVNQIGSLTESIEACKLAQDSGWGVMVSHRSGETEDTFIADLV 386 Query: 543 VGLRTGQIKTGAPCRSERLAKYNQLLRIEEELGAKAAYAGEKFHHP 680 VGL TGQIKTGAPCRS+RLAKYNQLLRIEEELG A YAG+ F HP Sbjct: 387 VGLCTGQIKTGAPCRSDRLAKYNQLLRIEEELGTAAKYAGKNFRHP 432
>sp|P09104|ENOG_HUMAN Gamma-enolase (2-phospho-D-glycerate hydro-lyase) (Neural enolase) (Neuron-specific enolase) (NSE) (Enolase 2) Length = 434 Score = 346 bits (887), Expect = 5e-95 Identities = 165/226 (73%), Positives = 194/226 (85%) Frame = +3 Query: 3 VGDEGGFAPNILDNFEGLELLKVAIEAAGYTGKIKIGMDVAASEFYKEGKYDLDFKNPHS 182 VGDEGGFAPNIL+N E LEL+K AI+ AGYT KI IGMDVAASEFY++GKYDLDFK+P + Sbjct: 207 VGDEGGFAPNILENSEALELVKEAIDKAGYTEKIVIGMDVAASEFYRDGKYDLDFKSP-T 265 Query: 183 DKSKWLTSSELAAVYTDMIHKYPIVSIEDPFDQDDWSAWTDFSGKAGIQIVGDDLTVTNP 362 D S+++T +L A+Y D + YP+VSIEDPFDQDDW+AW+ F+ GIQIVGDDLTVTNP Sbjct: 266 DPSRYITGDQLGALYQDFVRDYPVVSIEDPFDQDDWAAWSKFTANVGIQIVGDDLTVTNP 325 Query: 363 TRVQKGIDVKACNCLLLKVNQIGSVTESIQACKMSQNAGWGVMVSHRSGETEDNTIADLV 542 R+++ ++ KACNCLLLKVNQIGSVTE+IQACK++Q GWGVMVSHRSGETED IADLV Sbjct: 326 KRIERAVEEKACNCLLLKVNQIGSVTEAIQACKLAQENGWGVMVSHRSGETEDTFIADLV 385 Query: 543 VGLRTGQIKTGAPCRSERLAKYNQLLRIEEELGAKAAYAGEKFHHP 680 VGL TGQIKTGAPCRSERLAKYNQL+RIEEELG +A +AG F +P Sbjct: 386 VGLCTGQIKTGAPCRSERLAKYNQLMRIEEELGDEARFAGHNFRNP 431
>sp|P17183|ENOG_MOUSE Gamma-enolase (2-phospho-D-glycerate hydro-lyase) (Neural enolase) (Neuron-specific enolase) (NSE) (Enolase 2) Length = 434 Score = 345 bits (885), Expect = 9e-95 Identities = 164/226 (72%), Positives = 194/226 (85%) Frame = +3 Query: 3 VGDEGGFAPNILDNFEGLELLKVAIEAAGYTGKIKIGMDVAASEFYKEGKYDLDFKNPHS 182 VGDEGGFAPNIL+N E LEL+K AI+ AGYT K+ IGMDVAASEFY++GKYDLDFK+P + Sbjct: 207 VGDEGGFAPNILENSEALELVKEAIDKAGYTEKMVIGMDVAASEFYRDGKYDLDFKSP-A 265 Query: 183 DKSKWLTSSELAAVYTDMIHKYPIVSIEDPFDQDDWSAWTDFSGKAGIQIVGDDLTVTNP 362 D S+++T +L A+Y D + YP+VSIEDPFDQDDW+AW+ F+ GIQIVGDDLTVTNP Sbjct: 266 DPSRYITGDQLGALYQDFVRNYPVVSIEDPFDQDDWAAWSKFTANVGIQIVGDDLTVTNP 325 Query: 363 TRVQKGIDVKACNCLLLKVNQIGSVTESIQACKMSQNAGWGVMVSHRSGETEDNTIADLV 542 R+++ ++ KACNCLLLKVNQIGSVTE+IQACK++Q GWGVMVSHRSGETED IADLV Sbjct: 326 KRIERAVEEKACNCLLLKVNQIGSVTEAIQACKLAQENGWGVMVSHRSGETEDTFIADLV 385 Query: 543 VGLRTGQIKTGAPCRSERLAKYNQLLRIEEELGAKAAYAGEKFHHP 680 VGL TGQIKTGAPCRSERLAKYNQL+RIEEELG +A +AG F +P Sbjct: 386 VGLCTGQIKTGAPCRSERLAKYNQLMRIEEELGDEARFAGHNFRNP 431
>sp|P07323|ENOG_RAT Gamma-enolase (2-phospho-D-glycerate hydro-lyase) (Neural enolase) (Neuron-specific enolase) (NSE) (Enolase 2) Length = 434 Score = 344 bits (882), Expect = 2e-94 Identities = 164/226 (72%), Positives = 193/226 (85%) Frame = +3 Query: 3 VGDEGGFAPNILDNFEGLELLKVAIEAAGYTGKIKIGMDVAASEFYKEGKYDLDFKNPHS 182 VGDEGGFAPNIL+N E LEL+K AI+ AGYT K+ IGMDVAASEFY++GKYDLDFK+P + Sbjct: 207 VGDEGGFAPNILENSEALELVKEAIDKAGYTEKMVIGMDVAASEFYRDGKYDLDFKSP-A 265 Query: 183 DKSKWLTSSELAAVYTDMIHKYPIVSIEDPFDQDDWSAWTDFSGKAGIQIVGDDLTVTNP 362 D S+ +T +L A+Y D + YP+VSIEDPFDQDDW+AW+ F+ GIQIVGDDLTVTNP Sbjct: 266 DPSRCITGDQLGALYQDFVRNYPVVSIEDPFDQDDWAAWSKFTANVGIQIVGDDLTVTNP 325 Query: 363 TRVQKGIDVKACNCLLLKVNQIGSVTESIQACKMSQNAGWGVMVSHRSGETEDNTIADLV 542 R+++ ++ KACNCLLLKVNQIGSVTE+IQACK++Q GWGVMVSHRSGETED IADLV Sbjct: 326 KRIERAVEEKACNCLLLKVNQIGSVTEAIQACKLAQENGWGVMVSHRSGETEDTFIADLV 385 Query: 543 VGLRTGQIKTGAPCRSERLAKYNQLLRIEEELGAKAAYAGEKFHHP 680 VGL TGQIKTGAPCRSERLAKYNQL+RIEEELG +A +AG F +P Sbjct: 386 VGLCTGQIKTGAPCRSERLAKYNQLMRIEEELGEEARFAGHNFRNP 431
>sp|Q9PVK2|ENOA_ALLMI Alpha-enolase (2-phospho-D-glycerate hydro-lyase) (Phosphopyruvate hydratase) Length = 434 Score = 344 bits (882), Expect = 2e-94 Identities = 166/226 (73%), Positives = 191/226 (84%) Frame = +3 Query: 3 VGDEGGFAPNILDNFEGLELLKVAIEAAGYTGKIKIGMDVAASEFYKEGKYDLDFKNPHS 182 VGDEGGFAPNIL+N E LELLK AI AGY+ KI IGMDVAASEFY++GKYDLDFK+P Sbjct: 207 VGDEGGFAPNILENKEALELLKNAINKAGYSDKIVIGMDVAASEFYRDGKYDLDFKSP-D 265 Query: 183 DKSKWLTSSELAAVYTDMIHKYPIVSIEDPFDQDDWSAWTDFSGKAGIQIVGDDLTVTNP 362 D S+++T +LA +Y + YP+VSIEDPFDQDDW+AW F+ GIQ+VGDDLTVTNP Sbjct: 266 DPSRYITPDQLADLYKSFVKNYPVVSIEDPFDQDDWAAWKKFTASVGIQVVGDDLTVTNP 325 Query: 363 TRVQKGIDVKACNCLLLKVNQIGSVTESIQACKMSQNAGWGVMVSHRSGETEDNTIADLV 542 R+ K +D KACNCLLLKVNQIGSVTES+QACK++Q+ GWGVMVSHRSGETED IADLV Sbjct: 326 KRIAKAVDDKACNCLLLKVNQIGSVTESLQACKLAQSNGWGVMVSHRSGETEDTFIADLV 385 Query: 543 VGLRTGQIKTGAPCRSERLAKYNQLLRIEEELGAKAAYAGEKFHHP 680 VGL TGQIKTGAPCRSERLAKYNQ+LRIEEELG+KA +AG F +P Sbjct: 386 VGLCTGQIKTGAPCRSERLAKYNQILRIEEELGSKARFAGRNFRNP 431
>sp|P19140|ENOA_ANAPL Alpha-enolase (2-phospho-D-glycerate hydro-lyase) (Tau-crystallin) Length = 434 Score = 343 bits (881), Expect = 3e-94 Identities = 165/226 (73%), Positives = 191/226 (84%) Frame = +3 Query: 3 VGDEGGFAPNILDNFEGLELLKVAIEAAGYTGKIKIGMDVAASEFYKEGKYDLDFKNPHS 182 VGDEGGFAPNIL+N E LELLK AI AGY+ K+ IGMDVAASEFY++GKYDLDFK+P Sbjct: 207 VGDEGGFAPNILENKEALELLKTAIGKAGYSDKVVIGMDVAASEFYRDGKYDLDFKSP-D 265 Query: 183 DKSKWLTSSELAAVYTDMIHKYPIVSIEDPFDQDDWSAWTDFSGKAGIQIVGDDLTVTNP 362 D S++++ +LA +Y + YP+VSIEDPFDQDDW AW F+G GIQ+VGDDLTVTNP Sbjct: 266 DPSRYISPDQLADLYKGFVKNYPVVSIEDPFDQDDWGAWKKFTGSVGIQVVGDDLTVTNP 325 Query: 363 TRVQKGIDVKACNCLLLKVNQIGSVTESIQACKMSQNAGWGVMVSHRSGETEDNTIADLV 542 R+ K ++ KACNCLLLKVNQIGSVTES+QACK++Q+ GWGVMVSHRSGETED IADLV Sbjct: 326 KRIAKAVEEKACNCLLLKVNQIGSVTESLQACKLAQSNGWGVMVSHRSGETEDTFIADLV 385 Query: 543 VGLRTGQIKTGAPCRSERLAKYNQLLRIEEELGAKAAYAGEKFHHP 680 VGL TGQIKTGAPCRSERLAKYNQLLRIEEELG+KA +AG F +P Sbjct: 386 VGLCTGQIKTGAPCRSERLAKYNQLLRIEEELGSKARFAGRNFRNP 431
Database: Non-redundant SwissProt sequences Posted date: Dec 6, 2005 7:40 AM Number of letters in database: 68,354,980 Number of sequences in database: 184,735 Database: swissprot.01 Posted date: Dec 6, 2005 8:18 AM Number of letters in database: 66,202,850 Number of sequences in database: 184,431 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 93,688,500 Number of Sequences: 369166 Number of extensions: 1839736 Number of successful extensions: 4982 Number of sequences better than 10.0: 10 Number of HSP's better than 10.0 without gapping: 4334 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 4416 length of database: 68,354,980 effective HSP length: 110 effective length of database: 48,034,130 effective search space used: 8550075140 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)