Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= DrC_00789 (906 letters) Database: Non-redundant SwissProt sequences 184,735 sequences; 68,354,980 total letters Score E Sequences producing significant alignments: (bits) Value sp|Q61074|PP2CG_MOUSE Protein phosphatase 2C gamma isoform ... 219 8e-57 sp|O15355|PP2CG_HUMAN Protein phosphatase 2C gamma isoform ... 218 2e-56 sp|P49595|PP2C1_CAEEL Probable protein phosphatase 2C F42G9... 216 5e-56 sp|P79126|PP2CG_BOVIN Protein phosphatase 2C gamma isoform ... 215 2e-55 sp|Q09172|PP2C2_SCHPO Protein phosphatase 2C homolog 2 (PP2... 158 2e-38 sp|P49444|PP2C_PARTE Protein phosphatase 2C (PP2C) 154 3e-37 sp|P49596|PP2C2_CAEEL Probable protein phosphatase 2C T23F1... 144 3e-34 sp|Q09173|PP2C3_SCHPO Protein phosphatase 2C homolog 3 (PP2... 142 1e-33 sp|P34221|PP2C3_YEAST Protein phosphatase 2C homolog 3 (PP2... 135 1e-31 sp|P39966|PP2C2_YEAST Protein phosphatase 2C homolog 2 (PP2... 135 1e-31
>sp|Q61074|PP2CG_MOUSE Protein phosphatase 2C gamma isoform (PP2C-gamma) (Protein phosphatase magnesium-dependent 1 gamma) (Protein phosphatase 1C) (Fibroblast growth factor inducible protein 13) (FIN13) Length = 542 Score = 219 bits (558), Expect = 8e-57 Identities = 112/232 (48%), Positives = 158/232 (68%), Gaps = 7/232 (3%) Frame = +1 Query: 184 RNAPGFDSGSTAVLSLINRKTNKVYVANVGDSRCVLCRNGEAVDLSIDHKPEDEIESQRI 363 + PG DSG+TAV++LI K ++ VAN GDSRCV+ G+A+D+S DHKPEDE+E RI Sbjct: 317 KEEPGSDSGTTAVVALIRGK--QLIVANAGDSRCVVSEAGKALDMSYDHKPEDEVELARI 374 Query: 364 AKAGGMLSEDGRVNGGLNLSRSLGDHSYKKNKEMEMKDQMISAFPDIQIIDLKPYEDEFL 543 AGG ++ DGRVNGGLNLSR++GDH YK+NK + ++QMISA PDI+++ L + EF+ Sbjct: 375 KNAGGKVTMDGRVNGGLNLSRAIGDHFYKRNKNLPPQEQMISALPDIKVLTLTD-DHEFM 433 Query: 544 VLACDGIWNTFSSQQLMDFVKKRISTMP-------VTEIISEIFSHCLAPNTSGDGTGCD 702 V+ACDGIWN SSQ+++DF++ +IS ++ I+ E+ CLAP+TSGDGTGCD Sbjct: 434 VIACDGIWNVMSSQEVVDFIQSKISQRDENGELRLLSSIVEELLDQCLAPDTSGDGTGCD 493 Query: 703 NMTCIIVTFKFPSPISICNGKSNKKRAATKDLDEESIPVTKVTKTQNEESVK 858 NMTCII+ FK + + + +S K++ EE++ T N + K Sbjct: 494 NMTCIIICFKPRNTVEL-QAESGKRKL------EEALSTEGAEDTGNSDKKK 538
>sp|O15355|PP2CG_HUMAN Protein phosphatase 2C gamma isoform (PP2C-gamma) (Protein phosphatase magnesium-dependent 1 gamma) (Protein phosphatase 1C) Length = 546 Score = 218 bits (555), Expect = 2e-56 Identities = 112/230 (48%), Positives = 154/230 (66%), Gaps = 26/230 (11%) Frame = +1 Query: 184 RNAPGFDSGSTAVLSLINRKTNKVYVANVGDSRCVLCRNGEAVDLSIDHKPEDEIESQRI 363 + PG DSG+TAV++LI K ++ VAN GDSRCV+ G+A+D+S DHKPEDE+E RI Sbjct: 320 KEEPGSDSGTTAVVALIRGK--QLIVANAGDSRCVVSEAGKALDMSYDHKPEDEVELARI 377 Query: 364 AKAGGMLSEDGRVNGGLNLSRSLGDHSYKKNKEMEMKDQMISAFPDIQIIDLKPYEDEFL 543 AGG ++ DGRVNGGLNLSR++GDH YK+NK + ++QMISA PDI+++ L + EF+ Sbjct: 378 KNAGGKVTMDGRVNGGLNLSRAIGDHFYKRNKNLPPEEQMISALPDIKVLTLTD-DHEFM 436 Query: 544 VLACDGIWNTFSSQQLMDFVKKRISTMP-------VTEIISEIFSHCLAPNTSGDGTGCD 702 V+ACDGIWN SSQ+++DF++ +IS ++ I+ E+ CLAP+TSGDGTGCD Sbjct: 437 VIACDGIWNVMSSQEVVDFIQSKISQRDENGELRLLSSIVEELLDQCLAPDTSGDGTGCD 496 Query: 703 NMTCIIVTFKFPSPISIC-------------------NGKSNKKRAATKD 795 NMTCII+ FK + + NG S+KK+ A +D Sbjct: 497 NMTCIIICFKPRNTAELQPESGKRKLEEVLSTEGAEENGNSDKKKKAKRD 546
>sp|P49595|PP2C1_CAEEL Probable protein phosphatase 2C F42G9.1 (PP2C) Length = 491 Score = 216 bits (551), Expect = 5e-56 Identities = 108/180 (60%), Positives = 138/180 (76%), Gaps = 1/180 (0%) Frame = +1 Query: 193 PGFDSGSTAVLSLINRKTNKVYVANVGDSRCVLCRNGEAVDLSIDHKPEDEIESQRIAKA 372 PG DSG+TA + L+ + +KV VAN GDSR VLCRNG+AVDLS+DHKPEDE+E+ RI A Sbjct: 311 PGEDSGTTACVCLVGK--DKVIVANAGDSRAVLCRNGKAVDLSVDHKPEDEVETNRIHAA 368 Query: 373 GGMLSEDGRVNGGLNLSRSLGDHSYKKNKEMEMKDQMISAFPDIQIIDLKPYEDEFLVLA 552 GG + EDGRVNGGLNLSR+ GDH+YKKN+E+ +K+QMI+A PD++I L P EDEF+V+A Sbjct: 369 GGQI-EDGRVNGGLNLSRAFGDHAYKKNQELGLKEQMITALPDVKIEALTP-EDEFIVVA 426 Query: 553 CDGIWNTFSSQQLMDFVKKRIST-MPVTEIISEIFSHCLAPNTSGDGTGCDNMTCIIVTF 729 CDGIWN+ SQQ++DFV+ ++ E+ + CLA +T GDGTGCDNMT I TF Sbjct: 427 CDGIWNSMESQQVVDFVRDLLAKGSSCAEVCDALCDACLADSTDGDGTGCDNMTVICTTF 486
>sp|P79126|PP2CG_BOVIN Protein phosphatase 2C gamma isoform (PP2C-gamma) (Protein phosphatase magnesium-dependent 1 gamma) (Protein phosphatase 1B) (Magnesium-dependent calcium inhibitable phosphatase) (MCPP) Length = 543 Score = 215 bits (547), Expect = 2e-55 Identities = 104/190 (54%), Positives = 141/190 (74%), Gaps = 7/190 (3%) Frame = +1 Query: 184 RNAPGFDSGSTAVLSLINRKTNKVYVANVGDSRCVLCRNGEAVDLSIDHKPEDEIESQRI 363 + PG DSG+TAV++LI K ++ VAN GDSRCV+ G+A+D+S DHKPEDE+E RI Sbjct: 318 KEEPGSDSGTTAVVALIRGK--QLIVANAGDSRCVVSEAGKALDMSYDHKPEDEVELARI 375 Query: 364 AKAGGMLSEDGRVNGGLNLSRSLGDHSYKKNKEMEMKDQMISAFPDIQIIDLKPYEDEFL 543 AGG ++ DGRVNGGLNLSR++GDH YK+NK + ++QMISA PDI+++ L + EF+ Sbjct: 376 KNAGGKVTMDGRVNGGLNLSRAIGDHFYKRNKNLPPEEQMISALPDIKVLTLTD-DHEFM 434 Query: 544 VLACDGIWNTFSSQQLMDFVKKRISTMP-------VTEIISEIFSHCLAPNTSGDGTGCD 702 V+ACDGIWN SSQ+++DF++ +IS ++ I+ + CLAP+TSGDGTGCD Sbjct: 435 VIACDGIWNVMSSQEVIDFIQSKISQRDENGELRLLSSIVEYLLDQCLAPDTSGDGTGCD 494 Query: 703 NMTCIIVTFK 732 NMTCII+ FK Sbjct: 495 NMTCIIICFK 504
>sp|Q09172|PP2C2_SCHPO Protein phosphatase 2C homolog 2 (PP2C-2) Length = 370 Score = 158 bits (399), Expect = 2e-38 Identities = 85/176 (48%), Positives = 115/176 (65%), Gaps = 1/176 (0%) Frame = +1 Query: 205 SGSTAVLSLINRKTNKVYVANVGDSRCVLCRNGEAVDLSIDHKPEDEIESQRIAKAGGML 384 SG TA +LI +Y AN GDSR VL R G A LS DHKP +++E RI AGG + Sbjct: 119 SGCTATTALIVDH-QVIYCANAGDSRTVLGRKGTAEPLSFDHKPNNDVEKARITAAGGFI 177 Query: 385 SEDGRVNGGLNLSRSLGDHSYKKNKEMEMKDQMISAFPDIQIIDLKPYEDEFLVLACDGI 564 + GRVNG L LSR++GD YKK+ + + Q+++AFPD+ I ++ P +DEFL+LACDGI Sbjct: 178 -DFGRVNGSLALSRAIGDFEYKKDSSLPPEKQIVTAFPDVVIHNIDP-DDEFLILACDGI 235 Query: 565 WNTFSSQQLMDFVKKRISTMPVTEIISE-IFSHCLAPNTSGDGTGCDNMTCIIVTF 729 W+ SSQQ+++FV++ I E+I E + C+A N+ G GCDNMT IV F Sbjct: 236 WDCKSSQQVVEFVRRGIVARQSLEVICENLMDRCIASNSESCGIGCDNMTICIVAF 291
>sp|P49444|PP2C_PARTE Protein phosphatase 2C (PP2C) Length = 300 Score = 154 bits (390), Expect = 3e-37 Identities = 83/178 (46%), Positives = 119/178 (66%), Gaps = 5/178 (2%) Frame = +1 Query: 205 SGSTAVLSLINRKTNKVYVANVGDSRCVLCRNGEAVDLSIDHKPEDEIESQRIAKAGGML 384 +G TA ++LI + T +YVAN GDSR VLCRN D+S+DHKP++ E RI +AGG + Sbjct: 124 AGCTANVALIYKNT--LYVANAGDSRSVLCRNNTNHDMSVDHKPDNPEEKSRIERAGGFV 181 Query: 385 SEDGRVNGGLNLSRSLGDHSYKKNKEMEMKDQMISAFPDIQIIDLKPYEDEFLVLACDGI 564 S DGRVNG LNLSR+LGD YK++ ++ +Q+I A PD++ +L P +D+F+++ CDG+ Sbjct: 182 S-DGRVNGNLNLSRALGDLEYKRDNKLRSNEQLIIALPDVKKTELTP-QDKFILMGCDGV 239 Query: 565 WNTFSSQQLMDFVKKRISTMPVTEII-----SEIFSHCLAPNTSGDGTGCDNMTCIIV 723 + T + Q+L+ V I VTE + ++ LAP+TS GTGCDNMT I+V Sbjct: 240 FETLNHQELLKQVNSTIGQAQVTEELLKKAAEDLLDQLLAPDTS-QGTGCDNMTTILV 296
>sp|P49596|PP2C2_CAEEL Probable protein phosphatase 2C T23F11.1 (PP2C) Length = 356 Score = 144 bits (364), Expect = 3e-34 Identities = 80/174 (45%), Positives = 112/174 (64%), Gaps = 1/174 (0%) Frame = +1 Query: 205 SGSTAVLSLINRKTNKVYVANVGDSRCVLCRNGEAVDLSIDHKPEDEIESQRIAKAGGML 384 SG+TAV+ LI K VY N GDSR V GEA LS DHKP E E++RI AGG + Sbjct: 115 SGTTAVVVLI--KEGDVYCGNAGDSRAVSSVVGEARPLSFDHKPSHETEARRIIAAGGWV 172 Query: 385 SEDGRVNGGLNLSRSLGDHSYKKNKEMEMKDQMISAFPDIQIIDLKPYEDEFLVLACDGI 564 E RVNG L LSR+LGD ++K ++Q+++AFPD+ L P + EF+VLACDGI Sbjct: 173 -EFNRVNGNLALSRALGDFAFKNCDTKPAEEQIVTAFPDVITDKLTP-DHEFIVLACDGI 230 Query: 565 WNTFSSQQLMDFVKKRIS-TMPVTEIISEIFSHCLAPNTSGDGTGCDNMTCIIV 723 W+ ++Q+++DFV+++++ I E+ + CLAP+ G GCDNMT ++V Sbjct: 231 WDVMTNQEVVDFVREKLAEKRDPQSICEELLTRCLAPDCQMGGLGCDNMTVVLV 284
>sp|Q09173|PP2C3_SCHPO Protein phosphatase 2C homolog 3 (PP2C-3) Length = 414 Score = 142 bits (359), Expect = 1e-33 Identities = 82/174 (47%), Positives = 113/174 (64%), Gaps = 1/174 (0%) Frame = +1 Query: 205 SGSTAVLSLINRKTNKVYVANVGDSRCVLCRNGEAVDLSIDHKPEDEIESQRIAKAGGML 384 SG TA + L R NK+Y AN GDSR VL G A LS DHKP +E E RI AGG + Sbjct: 118 SGCTATVVL--RVGNKLYCANAGDSRTVLGSKGIAKPLSADHKPSNEAEKARICAAGGFV 175 Query: 385 SEDGRVNGGLNLSRSLGDHSYKKNKEMEMKDQMISAFPDIQIIDLKPYEDEFLVLACDGI 564 + GRVNG L LSR++GD + KN +E + Q+++A PD+ + ++ +DEF+VLACDGI Sbjct: 176 -DFGRVNGNLALSRAIGDFEF-KNSNLEPEKQIVTALPDVVVHEITD-DDEFVVLACDGI 232 Query: 565 WNTFSSQQLMDFVKKRISTMPVTEIISE-IFSHCLAPNTSGDGTGCDNMTCIIV 723 W+ +SQQ+++FV++ I E I+E + +C+A +T G GCDNMT IV Sbjct: 233 WDCKTSQQVIEFVRRGIVAGTSLEKIAENLMDNCIASDTETTGLGCDNMTVCIV 286
>sp|P34221|PP2C3_YEAST Protein phosphatase 2C homolog 3 (PP2C-3) Length = 468 Score = 135 bits (341), Expect = 1e-31 Identities = 75/175 (42%), Positives = 104/175 (59%), Gaps = 2/175 (1%) Frame = +1 Query: 205 SGSTAVLSLINRKTNKVYVANVGDSRCVLCRNGEAVDLSIDHKPEDEIESQRIAKAGGML 384 SG TA + L+++ + AN GDSR VL G + +S DHKP E RI A G + Sbjct: 118 SGCTATVILVSQLKKLLICANSGDSRTVLSTGGNSKAMSFDHKPTLLSEKSRIVAADGFV 177 Query: 385 SEDGRVNGGLNLSRSLGDHSYKKNKEMEMKDQMISAFPDIQIIDLKPYEDEFLVLACDGI 564 D RVNG L LSR++GD +K N ++ +Q+++ PDI +L EDEF++LACDGI Sbjct: 178 EMD-RVNGNLALSRAIGDFEFKSNTKLGPHEQVVTCVPDIICHNLNYDEDEFVILACDGI 236 Query: 565 WNTFSSQQLMDFVKKRIS--TMPVTEIISEIFSHCLAPNTSGDGTGCDNMTCIIV 723 W+ +SQ+ +D V IS M +++I S I C +P T G G GCDNM+ IV Sbjct: 237 WDCLTSQECVDLVHYGISQGNMTLSDISSRIVDVCCSPTTEGSGIGCDNMSISIV 291
>sp|P39966|PP2C2_YEAST Protein phosphatase 2C homolog 2 (PP2C-2) Length = 464 Score = 135 bits (341), Expect = 1e-31 Identities = 74/174 (42%), Positives = 100/174 (57%), Gaps = 1/174 (0%) Frame = +1 Query: 205 SGSTAVLSLINRKTNKVYVANVGDSRCVLCRNGEAVDLSIDHKPEDEIESQRIAKAGGML 384 SG TA L+++ N + N GDSR VL +G A LS DHKP E RI A G + Sbjct: 118 SGCTATSILVSKSQNLLVCGNAGDSRTVLATDGNAKALSYDHKPTLASEKSRIVAADGFV 177 Query: 385 SEDGRVNGGLNLSRSLGDHSYKKNKEMEMKDQMISAFPDIQIIDLKPYEDEFLVLACDGI 564 D RVNG L LSR++GD +K N ++ ++Q+++ PDI L DEF++LACDGI Sbjct: 178 EMD-RVNGNLALSRAIGDFEFKSNPKLGPEEQIVTCVPDILEHSLDYDRDEFVILACDGI 236 Query: 565 WNTFSSQQLMDFVKKRI-STMPVTEIISEIFSHCLAPNTSGDGTGCDNMTCIIV 723 W+ +SQ +D V + + EI S I C AP T G G GCDNM+ ++V Sbjct: 237 WDCLTSQDCVDLVHLGLREGKTLNEISSRIIDVCCAPTTEGTGIGCDNMSIVVV 290
Database: Non-redundant SwissProt sequences Posted date: Dec 6, 2005 7:40 AM Number of letters in database: 68,354,980 Number of sequences in database: 184,735 Database: swissprot.01 Posted date: Dec 6, 2005 8:18 AM Number of letters in database: 66,202,850 Number of sequences in database: 184,431 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 92,415,542 Number of Sequences: 369166 Number of extensions: 1882110 Number of successful extensions: 5258 Number of sequences better than 10.0: 10 Number of HSP's better than 10.0 without gapping: 5004 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 5170 length of database: 68,354,980 effective HSP length: 110 effective length of database: 48,034,130 effective search space used: 9174518830 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)