Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_020_G04
(905 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q61074|PP2CG_MOUSE Protein phosphatase 2C gamma isoform ... 219 8e-57
sp|O15355|PP2CG_HUMAN Protein phosphatase 2C gamma isoform ... 218 2e-56
sp|P49595|PP2C1_CAEEL Probable protein phosphatase 2C F42G9... 216 5e-56
sp|P79126|PP2CG_BOVIN Protein phosphatase 2C gamma isoform ... 215 2e-55
sp|Q09172|PP2C2_SCHPO Protein phosphatase 2C homolog 2 (PP2... 158 2e-38
sp|P49444|PP2C_PARTE Protein phosphatase 2C (PP2C) 154 3e-37
sp|P49596|PP2C2_CAEEL Probable protein phosphatase 2C T23F1... 144 3e-34
sp|Q09173|PP2C3_SCHPO Protein phosphatase 2C homolog 3 (PP2... 142 1e-33
sp|P34221|PP2C3_YEAST Protein phosphatase 2C homolog 3 (PP2... 135 1e-31
sp|P39966|PP2C2_YEAST Protein phosphatase 2C homolog 2 (PP2... 135 1e-31
>sp|Q61074|PP2CG_MOUSE Protein phosphatase 2C gamma isoform (PP2C-gamma) (Protein
phosphatase magnesium-dependent 1 gamma) (Protein
phosphatase 1C) (Fibroblast growth factor inducible
protein 13) (FIN13)
Length = 542
Score = 219 bits (558), Expect = 8e-57
Identities = 112/232 (48%), Positives = 158/232 (68%), Gaps = 7/232 (3%)
Frame = +1
Query: 184 RNAPGFDSGSTAVLSLINRKTNKVYVANVGDSRCVLCRNGEAVDLSIDHKPEDEIESQRI 363
+ PG DSG+TAV++LI K ++ VAN GDSRCV+ G+A+D+S DHKPEDE+E RI
Sbjct: 317 KEEPGSDSGTTAVVALIRGK--QLIVANAGDSRCVVSEAGKALDMSYDHKPEDEVELARI 374
Query: 364 AKAGGMLSEDGRVNGGLNLSRSLGDHSYKKNKEMEMKDQMISAFPDIQIIDLKPYEDEFL 543
AGG ++ DGRVNGGLNLSR++GDH YK+NK + ++QMISA PDI+++ L + EF+
Sbjct: 375 KNAGGKVTMDGRVNGGLNLSRAIGDHFYKRNKNLPPQEQMISALPDIKVLTLTD-DHEFM 433
Query: 544 VLACDGIWNTFSSQQLMDFVKKRISTMP-------VTEIISEIFSHCLAPNTSGDGTGCD 702
V+ACDGIWN SSQ+++DF++ +IS ++ I+ E+ CLAP+TSGDGTGCD
Sbjct: 434 VIACDGIWNVMSSQEVVDFIQSKISQRDENGELRLLSSIVEELLDQCLAPDTSGDGTGCD 493
Query: 703 NMTCIIVTFKFPSPISICNGKSNKKRAATKDLDEESIPVTKVTKTQNEESVK 858
NMTCII+ FK + + + +S K++ EE++ T N + K
Sbjct: 494 NMTCIIICFKPRNTVEL-QAESGKRKL------EEALSTEGAEDTGNSDKKK 538
>sp|O15355|PP2CG_HUMAN Protein phosphatase 2C gamma isoform (PP2C-gamma) (Protein
phosphatase magnesium-dependent 1 gamma) (Protein
phosphatase 1C)
Length = 546
Score = 218 bits (555), Expect = 2e-56
Identities = 112/230 (48%), Positives = 154/230 (66%), Gaps = 26/230 (11%)
Frame = +1
Query: 184 RNAPGFDSGSTAVLSLINRKTNKVYVANVGDSRCVLCRNGEAVDLSIDHKPEDEIESQRI 363
+ PG DSG+TAV++LI K ++ VAN GDSRCV+ G+A+D+S DHKPEDE+E RI
Sbjct: 320 KEEPGSDSGTTAVVALIRGK--QLIVANAGDSRCVVSEAGKALDMSYDHKPEDEVELARI 377
Query: 364 AKAGGMLSEDGRVNGGLNLSRSLGDHSYKKNKEMEMKDQMISAFPDIQIIDLKPYEDEFL 543
AGG ++ DGRVNGGLNLSR++GDH YK+NK + ++QMISA PDI+++ L + EF+
Sbjct: 378 KNAGGKVTMDGRVNGGLNLSRAIGDHFYKRNKNLPPEEQMISALPDIKVLTLTD-DHEFM 436
Query: 544 VLACDGIWNTFSSQQLMDFVKKRISTMP-------VTEIISEIFSHCLAPNTSGDGTGCD 702
V+ACDGIWN SSQ+++DF++ +IS ++ I+ E+ CLAP+TSGDGTGCD
Sbjct: 437 VIACDGIWNVMSSQEVVDFIQSKISQRDENGELRLLSSIVEELLDQCLAPDTSGDGTGCD 496
Query: 703 NMTCIIVTFKFPSPISIC-------------------NGKSNKKRAATKD 795
NMTCII+ FK + + NG S+KK+ A +D
Sbjct: 497 NMTCIIICFKPRNTAELQPESGKRKLEEVLSTEGAEENGNSDKKKKAKRD 546
>sp|P49595|PP2C1_CAEEL Probable protein phosphatase 2C F42G9.1 (PP2C)
Length = 491
Score = 216 bits (551), Expect = 5e-56
Identities = 108/180 (60%), Positives = 138/180 (76%), Gaps = 1/180 (0%)
Frame = +1
Query: 193 PGFDSGSTAVLSLINRKTNKVYVANVGDSRCVLCRNGEAVDLSIDHKPEDEIESQRIAKA 372
PG DSG+TA + L+ + +KV VAN GDSR VLCRNG+AVDLS+DHKPEDE+E+ RI A
Sbjct: 311 PGEDSGTTACVCLVGK--DKVIVANAGDSRAVLCRNGKAVDLSVDHKPEDEVETNRIHAA 368
Query: 373 GGMLSEDGRVNGGLNLSRSLGDHSYKKNKEMEMKDQMISAFPDIQIIDLKPYEDEFLVLA 552
GG + EDGRVNGGLNLSR+ GDH+YKKN+E+ +K+QMI+A PD++I L P EDEF+V+A
Sbjct: 369 GGQI-EDGRVNGGLNLSRAFGDHAYKKNQELGLKEQMITALPDVKIEALTP-EDEFIVVA 426
Query: 553 CDGIWNTFSSQQLMDFVKKRIST-MPVTEIISEIFSHCLAPNTSGDGTGCDNMTCIIVTF 729
CDGIWN+ SQQ++DFV+ ++ E+ + CLA +T GDGTGCDNMT I TF
Sbjct: 427 CDGIWNSMESQQVVDFVRDLLAKGSSCAEVCDALCDACLADSTDGDGTGCDNMTVICTTF 486
>sp|P79126|PP2CG_BOVIN Protein phosphatase 2C gamma isoform (PP2C-gamma) (Protein
phosphatase magnesium-dependent 1 gamma) (Protein
phosphatase 1B) (Magnesium-dependent calcium inhibitable
phosphatase) (MCPP)
Length = 543
Score = 215 bits (547), Expect = 2e-55
Identities = 104/190 (54%), Positives = 141/190 (74%), Gaps = 7/190 (3%)
Frame = +1
Query: 184 RNAPGFDSGSTAVLSLINRKTNKVYVANVGDSRCVLCRNGEAVDLSIDHKPEDEIESQRI 363
+ PG DSG+TAV++LI K ++ VAN GDSRCV+ G+A+D+S DHKPEDE+E RI
Sbjct: 318 KEEPGSDSGTTAVVALIRGK--QLIVANAGDSRCVVSEAGKALDMSYDHKPEDEVELARI 375
Query: 364 AKAGGMLSEDGRVNGGLNLSRSLGDHSYKKNKEMEMKDQMISAFPDIQIIDLKPYEDEFL 543
AGG ++ DGRVNGGLNLSR++GDH YK+NK + ++QMISA PDI+++ L + EF+
Sbjct: 376 KNAGGKVTMDGRVNGGLNLSRAIGDHFYKRNKNLPPEEQMISALPDIKVLTLTD-DHEFM 434
Query: 544 VLACDGIWNTFSSQQLMDFVKKRISTMP-------VTEIISEIFSHCLAPNTSGDGTGCD 702
V+ACDGIWN SSQ+++DF++ +IS ++ I+ + CLAP+TSGDGTGCD
Sbjct: 435 VIACDGIWNVMSSQEVIDFIQSKISQRDENGELRLLSSIVEYLLDQCLAPDTSGDGTGCD 494
Query: 703 NMTCIIVTFK 732
NMTCII+ FK
Sbjct: 495 NMTCIIICFK 504
>sp|Q09172|PP2C2_SCHPO Protein phosphatase 2C homolog 2 (PP2C-2)
Length = 370
Score = 158 bits (399), Expect = 2e-38
Identities = 85/176 (48%), Positives = 115/176 (65%), Gaps = 1/176 (0%)
Frame = +1
Query: 205 SGSTAVLSLINRKTNKVYVANVGDSRCVLCRNGEAVDLSIDHKPEDEIESQRIAKAGGML 384
SG TA +LI +Y AN GDSR VL R G A LS DHKP +++E RI AGG +
Sbjct: 119 SGCTATTALIVDH-QVIYCANAGDSRTVLGRKGTAEPLSFDHKPNNDVEKARITAAGGFI 177
Query: 385 SEDGRVNGGLNLSRSLGDHSYKKNKEMEMKDQMISAFPDIQIIDLKPYEDEFLVLACDGI 564
+ GRVNG L LSR++GD YKK+ + + Q+++AFPD+ I ++ P +DEFL+LACDGI
Sbjct: 178 -DFGRVNGSLALSRAIGDFEYKKDSSLPPEKQIVTAFPDVVIHNIDP-DDEFLILACDGI 235
Query: 565 WNTFSSQQLMDFVKKRISTMPVTEIISE-IFSHCLAPNTSGDGTGCDNMTCIIVTF 729
W+ SSQQ+++FV++ I E+I E + C+A N+ G GCDNMT IV F
Sbjct: 236 WDCKSSQQVVEFVRRGIVARQSLEVICENLMDRCIASNSESCGIGCDNMTICIVAF 291
>sp|P49444|PP2C_PARTE Protein phosphatase 2C (PP2C)
Length = 300
Score = 154 bits (390), Expect = 3e-37
Identities = 83/178 (46%), Positives = 119/178 (66%), Gaps = 5/178 (2%)
Frame = +1
Query: 205 SGSTAVLSLINRKTNKVYVANVGDSRCVLCRNGEAVDLSIDHKPEDEIESQRIAKAGGML 384
+G TA ++LI + T +YVAN GDSR VLCRN D+S+DHKP++ E RI +AGG +
Sbjct: 124 AGCTANVALIYKNT--LYVANAGDSRSVLCRNNTNHDMSVDHKPDNPEEKSRIERAGGFV 181
Query: 385 SEDGRVNGGLNLSRSLGDHSYKKNKEMEMKDQMISAFPDIQIIDLKPYEDEFLVLACDGI 564
S DGRVNG LNLSR+LGD YK++ ++ +Q+I A PD++ +L P +D+F+++ CDG+
Sbjct: 182 S-DGRVNGNLNLSRALGDLEYKRDNKLRSNEQLIIALPDVKKTELTP-QDKFILMGCDGV 239
Query: 565 WNTFSSQQLMDFVKKRISTMPVTEII-----SEIFSHCLAPNTSGDGTGCDNMTCIIV 723
+ T + Q+L+ V I VTE + ++ LAP+TS GTGCDNMT I+V
Sbjct: 240 FETLNHQELLKQVNSTIGQAQVTEELLKKAAEDLLDQLLAPDTS-QGTGCDNMTTILV 296
>sp|P49596|PP2C2_CAEEL Probable protein phosphatase 2C T23F11.1 (PP2C)
Length = 356
Score = 144 bits (364), Expect = 3e-34
Identities = 80/174 (45%), Positives = 112/174 (64%), Gaps = 1/174 (0%)
Frame = +1
Query: 205 SGSTAVLSLINRKTNKVYVANVGDSRCVLCRNGEAVDLSIDHKPEDEIESQRIAKAGGML 384
SG+TAV+ LI K VY N GDSR V GEA LS DHKP E E++RI AGG +
Sbjct: 115 SGTTAVVVLI--KEGDVYCGNAGDSRAVSSVVGEARPLSFDHKPSHETEARRIIAAGGWV 172
Query: 385 SEDGRVNGGLNLSRSLGDHSYKKNKEMEMKDQMISAFPDIQIIDLKPYEDEFLVLACDGI 564
E RVNG L LSR+LGD ++K ++Q+++AFPD+ L P + EF+VLACDGI
Sbjct: 173 -EFNRVNGNLALSRALGDFAFKNCDTKPAEEQIVTAFPDVITDKLTP-DHEFIVLACDGI 230
Query: 565 WNTFSSQQLMDFVKKRIS-TMPVTEIISEIFSHCLAPNTSGDGTGCDNMTCIIV 723
W+ ++Q+++DFV+++++ I E+ + CLAP+ G GCDNMT ++V
Sbjct: 231 WDVMTNQEVVDFVREKLAEKRDPQSICEELLTRCLAPDCQMGGLGCDNMTVVLV 284
>sp|Q09173|PP2C3_SCHPO Protein phosphatase 2C homolog 3 (PP2C-3)
Length = 414
Score = 142 bits (359), Expect = 1e-33
Identities = 82/174 (47%), Positives = 113/174 (64%), Gaps = 1/174 (0%)
Frame = +1
Query: 205 SGSTAVLSLINRKTNKVYVANVGDSRCVLCRNGEAVDLSIDHKPEDEIESQRIAKAGGML 384
SG TA + L R NK+Y AN GDSR VL G A LS DHKP +E E RI AGG +
Sbjct: 118 SGCTATVVL--RVGNKLYCANAGDSRTVLGSKGIAKPLSADHKPSNEAEKARICAAGGFV 175
Query: 385 SEDGRVNGGLNLSRSLGDHSYKKNKEMEMKDQMISAFPDIQIIDLKPYEDEFLVLACDGI 564
+ GRVNG L LSR++GD + KN +E + Q+++A PD+ + ++ +DEF+VLACDGI
Sbjct: 176 -DFGRVNGNLALSRAIGDFEF-KNSNLEPEKQIVTALPDVVVHEITD-DDEFVVLACDGI 232
Query: 565 WNTFSSQQLMDFVKKRISTMPVTEIISE-IFSHCLAPNTSGDGTGCDNMTCIIV 723
W+ +SQQ+++FV++ I E I+E + +C+A +T G GCDNMT IV
Sbjct: 233 WDCKTSQQVIEFVRRGIVAGTSLEKIAENLMDNCIASDTETTGLGCDNMTVCIV 286
>sp|P34221|PP2C3_YEAST Protein phosphatase 2C homolog 3 (PP2C-3)
Length = 468
Score = 135 bits (341), Expect = 1e-31
Identities = 75/175 (42%), Positives = 104/175 (59%), Gaps = 2/175 (1%)
Frame = +1
Query: 205 SGSTAVLSLINRKTNKVYVANVGDSRCVLCRNGEAVDLSIDHKPEDEIESQRIAKAGGML 384
SG TA + L+++ + AN GDSR VL G + +S DHKP E RI A G +
Sbjct: 118 SGCTATVILVSQLKKLLICANSGDSRTVLSTGGNSKAMSFDHKPTLLSEKSRIVAADGFV 177
Query: 385 SEDGRVNGGLNLSRSLGDHSYKKNKEMEMKDQMISAFPDIQIIDLKPYEDEFLVLACDGI 564
D RVNG L LSR++GD +K N ++ +Q+++ PDI +L EDEF++LACDGI
Sbjct: 178 EMD-RVNGNLALSRAIGDFEFKSNTKLGPHEQVVTCVPDIICHNLNYDEDEFVILACDGI 236
Query: 565 WNTFSSQQLMDFVKKRIS--TMPVTEIISEIFSHCLAPNTSGDGTGCDNMTCIIV 723
W+ +SQ+ +D V IS M +++I S I C +P T G G GCDNM+ IV
Sbjct: 237 WDCLTSQECVDLVHYGISQGNMTLSDISSRIVDVCCSPTTEGSGIGCDNMSISIV 291
>sp|P39966|PP2C2_YEAST Protein phosphatase 2C homolog 2 (PP2C-2)
Length = 464
Score = 135 bits (341), Expect = 1e-31
Identities = 74/174 (42%), Positives = 100/174 (57%), Gaps = 1/174 (0%)
Frame = +1
Query: 205 SGSTAVLSLINRKTNKVYVANVGDSRCVLCRNGEAVDLSIDHKPEDEIESQRIAKAGGML 384
SG TA L+++ N + N GDSR VL +G A LS DHKP E RI A G +
Sbjct: 118 SGCTATSILVSKSQNLLVCGNAGDSRTVLATDGNAKALSYDHKPTLASEKSRIVAADGFV 177
Query: 385 SEDGRVNGGLNLSRSLGDHSYKKNKEMEMKDQMISAFPDIQIIDLKPYEDEFLVLACDGI 564
D RVNG L LSR++GD +K N ++ ++Q+++ PDI L DEF++LACDGI
Sbjct: 178 EMD-RVNGNLALSRAIGDFEFKSNPKLGPEEQIVTCVPDILEHSLDYDRDEFVILACDGI 236
Query: 565 WNTFSSQQLMDFVKKRI-STMPVTEIISEIFSHCLAPNTSGDGTGCDNMTCIIV 723
W+ +SQ +D V + + EI S I C AP T G G GCDNM+ ++V
Sbjct: 237 WDCLTSQDCVDLVHLGLREGKTLNEISSRIIDVCCAPTTEGTGIGCDNMSIVVV 290
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 92,231,021
Number of Sequences: 369166
Number of extensions: 1875359
Number of successful extensions: 5249
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 4995
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5161
length of database: 68,354,980
effective HSP length: 110
effective length of database: 48,034,130
effective search space used: 9174518830
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)