Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= DrC_00756 (1131 letters) Database: Non-redundant SwissProt sequences 184,735 sequences; 68,354,980 total letters Score E Sequences producing significant alignments: (bits) Value sp|Q96MU7|YT521_HUMAN Putative splicing factor YT521 198 3e-50 sp|Q9QY02|YT521_RAT Putative splicing factor YT521 (RA301-b... 194 4e-49 sp|Q9Y5A9|YTHD2_HUMAN YTH domain protein 2 (High-glucose-re... 63 1e-09 sp|Q9BYJ9|YTHD1_HUMAN YTH domain protein 1 (Dermatomyositis... 57 1e-07 sp|P59326|YTHD1_MOUSE YTH domain protein 1 (Dermatomyositis... 56 2e-07 sp|Q9NYU1|UGGG2_HUMAN UDP-glucose:glycoprotein glucosyltran... 33 2.0 sp|Q9QZQ0|NPAS3_MOUSE Neuronal PAS domain protein 3 (Neuron... 33 2.0 sp|Q9HC84|MUC5B_HUMAN Mucin-5B precursor (Mucin 5 subtype B... 31 5.7 sp|P47642|ATPD_MYCGE ATP synthase delta chain 31 7.5 sp|O52788|PTK_ACIJO Tyrosine-protein kinase ptk 30 9.8
>sp|Q96MU7|YT521_HUMAN Putative splicing factor YT521 Length = 727 Score = 198 bits (503), Expect = 3e-50 Identities = 103/194 (53%), Positives = 129/194 (66%), Gaps = 14/194 (7%) Frame = +2 Query: 155 TRIKYLFHEARYFMIKSNNFENVSLAKVKNVWSTTRANEIRLNKAYYETKNVLLIFSVKE 334 +++KY+ +AR+F+IKSNN ENVSLAK K VWST NE +LN A+ ++V+LIFSV+E Sbjct: 346 SKLKYVLQDARFFLIKSNNHENVSLAKAKGVWSTLPVNEKKLNLAFRSARSVILIFSVRE 405 Query: 335 SGKFQGYARLSSASNPK-KHINWVLPTHMSQKQLSGIFQIDWLSREEVPFSKTNHLVNAW 511 SGKFQG+ARLSS S+ I+WVLP MS K L G+F+IDW+ R E+PF+K+ HL N W Sbjct: 406 SGKFQGFARLSSESHHGGSPIHWVLPAGMSAKMLGGVFKIDWICRRELPFTKSAHLTNPW 465 Query: 512 NEHKPVKIGRDGQEIEPSCGEFLCRLFVLDEDCKFNEIIDKAK-----------AGPPEY 658 NEHKPVKIGRDGQEIE CG LC LF DE ++I K + G P Sbjct: 466 NEHKPVKIGRDGQEIELECGTQLCLLFPPDESIDLYQVIHKMRHKRRMHSQPRSRGRPSR 525 Query: 659 RD--RDSNRTHPSD 694 R+ RD R P D Sbjct: 526 REPVRDVGRRRPED 539
>sp|Q9QY02|YT521_RAT Putative splicing factor YT521 (RA301-binding protein) Length = 738 Score = 194 bits (493), Expect = 4e-49 Identities = 102/194 (52%), Positives = 128/194 (65%), Gaps = 14/194 (7%) Frame = +2 Query: 155 TRIKYLFHEARYFMIKSNNFENVSLAKVKNVWSTTRANEIRLNKAYYETKNVLLIFSVKE 334 +++K + +AR+F+IKSNN ENVSLAK K VWST NE +LN A+ ++V+LIFSV+E Sbjct: 349 SKLKSVLQDARFFLIKSNNHENVSLAKAKGVWSTLPVNEKKLNLAFRSARSVILIFSVRE 408 Query: 335 SGKFQGYARLSSASNPK-KHINWVLPTHMSQKQLSGIFQIDWLSREEVPFSKTNHLVNAW 511 SGKFQG+ARLSS S+ I+WVLP MS K L G+F+IDW+ R E+PF+K+ HL N W Sbjct: 409 SGKFQGFARLSSESHHGGSPIHWVLPAGMSAKMLGGVFKIDWICRRELPFTKSAHLTNPW 468 Query: 512 NEHKPVKIGRDGQEIEPSCGEFLCRLFVLDEDCKFNEIIDKAK-----------AGPPEY 658 NEHKPVKIGRDGQEIE CG LC LF DE ++I K + G P Sbjct: 469 NEHKPVKIGRDGQEIELECGTQLCLLFPPDESIDLYQLIHKMRHKRRMHSQPRSRGRPSR 528 Query: 659 RD--RDSNRTHPSD 694 R+ RD R P D Sbjct: 529 REPVRDVGRRRPED 542
>sp|Q9Y5A9|YTHD2_HUMAN YTH domain protein 2 (High-glucose-regulated protein 8) (NY-REN-2 antigen) (CLL-associated antigen KW-14) Length = 579 Score = 63.2 bits (152), Expect = 1e-09 Identities = 46/143 (32%), Positives = 68/143 (47%), Gaps = 4/143 (2%) Frame = +2 Query: 140 NYRLPTRIKYLFHEARYFMIKSNNFENVSLAKVKNVWSTTRANEIRLNKAYYETKN---V 310 NY P + R F+IKS + +++ + N+W +T RL+ AY V Sbjct: 397 NYN-PKDFDWNLKHGRVFIIKSYSEDDIHRSIKYNIWCSTEHGNKRLDAAYRSMNGKGPV 455 Query: 311 LLIFSVKESGKFQGYARLSSASNPKKHIN-WVLPTHMSQKQLSGIFQIDWLSREEVPFSK 487 L+FSV SG F G A + SA + W SQ + G F + W+ ++VP S+ Sbjct: 456 YLLFSVNGSGHFCGVAEMKSAVDYNTCAGVW------SQDKWKGRFDVRWIFVKDVPNSQ 509 Query: 488 TNHLVNAWNEHKPVKIGRDGQEI 556 H+ NE+KPV RD QE+ Sbjct: 510 LRHIRLENNENKPVTNSRDTQEV 532
>sp|Q9BYJ9|YTHD1_HUMAN YTH domain protein 1 (Dermatomyositis associated with cancer putative autoantigen 1) (DACA-1) Length = 559 Score = 56.6 bits (135), Expect = 1e-07 Identities = 39/139 (28%), Positives = 67/139 (48%), Gaps = 4/139 (2%) Frame = +2 Query: 152 PTRIKYLFHEARYFMIKSNNFENVSLAKVKNVWSTTRANEIRLNKAYYETKN---VLLIF 322 P ++ R F+IKS + +++ + ++W +T RL+ A+ + V L+F Sbjct: 379 PKEFEWNLKSGRVFIIKSYSEDDIHRSIKYSIWCSTEHGNKRLDSAFRCMSSKGPVYLLF 438 Query: 323 SVKESGKFQGYARLSSASNPKKHIN-WVLPTHMSQKQLSGIFQIDWLSREEVPFSKTNHL 499 SV SG F G A + S + W SQ + G F + W+ ++VP ++ H+ Sbjct: 439 SVNGSGHFCGVAEMKSPVDYGTSAGVW------SQDKWKGKFDVQWIFVKDVPNNQLRHI 492 Query: 500 VNAWNEHKPVKIGRDGQEI 556 N++KPV RD QE+ Sbjct: 493 RLENNDNKPVTNSRDTQEV 511
>sp|P59326|YTHD1_MOUSE YTH domain protein 1 (Dermatomyositis associated with cancer putative autoantigen 1 homolog) (DACA-1 homolog) Length = 559 Score = 56.2 bits (134), Expect = 2e-07 Identities = 39/139 (28%), Positives = 66/139 (47%), Gaps = 4/139 (2%) Frame = +2 Query: 152 PTRIKYLFHEARYFMIKSNNFENVSLAKVKNVWSTTRANEIRLNKAYYETKN---VLLIF 322 P + R F+IKS + +++ + ++W +T RL+ A+ + V L+F Sbjct: 379 PKEFDWNLKSGRVFIIKSYSEDDIHRSIKYSIWCSTEHGNKRLDGAFRSMSSKGPVYLLF 438 Query: 323 SVKESGKFQGYARLSSASNPKKHIN-WVLPTHMSQKQLSGIFQIDWLSREEVPFSKTNHL 499 SV SG F G A + S + W SQ + G F + W+ ++VP ++ H+ Sbjct: 439 SVNGSGHFCGVAEMKSPVDYGTSAGVW------SQDKWKGKFDVKWIFVKDVPNNQLRHI 492 Query: 500 VNAWNEHKPVKIGRDGQEI 556 N++KPV RD QE+ Sbjct: 493 RLENNDNKPVTNSRDTQEV 511
>sp|Q9NYU1|UGGG2_HUMAN UDP-glucose:glycoprotein glucosyltransferase 2 precursor (UDP-glucose ceramide glucosyltransferase-like 1) (UDP--Glc:glycoprotein glucosyltransferase 2) (HUGT2) Length = 1516 Score = 32.7 bits (73), Expect = 2.0 Identities = 20/67 (29%), Positives = 35/67 (52%), Gaps = 4/67 (5%) Frame = +2 Query: 233 KVKNVWSTTRANEIRLNKAYYETKNVLLIFSVKESGKFQGYAR---LSSASNPKKHIN-W 400 K K +W + ++ + L+K + K+VL IFSV ++ + R LS N K + W Sbjct: 1205 KTKGLWDSIKSFTVSLHKENKKEKDVLNIFSVASGHLYERFLRIMMLSVLRNTKTPVKFW 1264 Query: 401 VLPTHMS 421 +L ++S Sbjct: 1265 LLKNYLS 1271
>sp|Q9QZQ0|NPAS3_MOUSE Neuronal PAS domain protein 3 (Neuronal PAS3) (Member of PAS protein 6) (MOP6) Length = 925 Score = 32.7 bits (73), Expect = 2.0 Identities = 18/65 (27%), Positives = 31/65 (47%) Frame = +2 Query: 101 QRICTQSSPNVDANYRLPTRIKYLFHEARYFMIKSNNFENVSLAKVKNVWSTTRANEIRL 280 +R+ + SSP +DA P R+ H A IK+ E ++ ++W+ EI Sbjct: 620 RRLSSASSPGLDAGLVEPPRLLSSPHSASVLKIKTEIAEPINFDNESSIWNYPPNREISR 679 Query: 281 NKAYY 295 N++ Y Sbjct: 680 NESPY 684
>sp|Q9HC84|MUC5B_HUMAN Mucin-5B precursor (Mucin 5 subtype B, tracheobronchial) (High molecular weight salivary mucin MG1) (Sublingual gland mucin) Length = 5703 Score = 31.2 bits (69), Expect = 5.7 Identities = 18/40 (45%), Positives = 23/40 (57%) Frame = +3 Query: 663 IATQIAPTRQTAATKTTIATNQFPMVNLAMMTIDPNITAA 782 IAT + PT TA T +T+ T P V AM T+ P TA+ Sbjct: 4795 IATVMVPTGSTATTSSTLGTAHTPKVVTAMATM-PTATAS 4833
>sp|P47642|ATPD_MYCGE ATP synthase delta chain Length = 176 Score = 30.8 bits (68), Expect = 7.5 Identities = 24/109 (22%), Positives = 50/109 (45%), Gaps = 11/109 (10%) Frame = +2 Query: 158 RIKYLFHEARYFMIKSNNFENVSLAKVKNVWSTTRANEIRLNKAYYETKNVLLIFSVKES 337 ++K ++ E +F+ NF++ SL+ + N ++ T+ ++IRL ++ + + Sbjct: 20 QVKKIYEECHFFLKLMRNFKDGSLSFLLNSYTLTKPDKIRLVDKLFKNHFCQVFVDFLKV 79 Query: 338 GKFQGYARLSSAS--------NPKKHINW---VLPTHMSQKQLSGIFQI 451 +GY L + +KHI + + +S KQL+ I I Sbjct: 80 IILKGYFTLVEQAIKYFFDNVESQKHIQFIKIITAFELSSKQLNKIIAI 128
>sp|O52788|PTK_ACIJO Tyrosine-protein kinase ptk Length = 733 Score = 30.4 bits (67), Expect = 9.8 Identities = 25/110 (22%), Positives = 45/110 (40%), Gaps = 17/110 (15%) Frame = +2 Query: 128 NVDANYRLPTRIKYLFHEARYFMIKSNNFENVSLAKVKN---------VWSTTRANEIRL 280 N+ A++R +I+ F + ++ + + + + K +W+ + + +L Sbjct: 151 NIPASFR-DKKIELRFKDGQFSLTNTQTEQVILTGKTNQSNTLRTADGLWNISIYTQDQL 209 Query: 281 NKAYYETK--------NVLLIFSVKESGKFQGYARLSSASNPKKHINWVL 406 N Y K N+L +SV E GK G L+ K HI VL Sbjct: 210 NDVYLIQKQSLPAAVNNILTNYSVAEKGKLTGILGLNYQGTDKTHITQVL 259
Database: Non-redundant SwissProt sequences Posted date: Dec 6, 2005 7:40 AM Number of letters in database: 68,354,980 Number of sequences in database: 184,735 Database: swissprot.01 Posted date: Dec 6, 2005 8:18 AM Number of letters in database: 66,202,850 Number of sequences in database: 184,431 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 109,687,304 Number of Sequences: 369166 Number of extensions: 1993604 Number of successful extensions: 4262 Number of sequences better than 10.0: 10 Number of HSP's better than 10.0 without gapping: 4140 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 4255 length of database: 68,354,980 effective HSP length: 112 effective length of database: 47,664,660 effective search space used: 12583470240 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)