Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= DrC_00730 (856 letters) Database: Non-redundant SwissProt sequences 184,735 sequences; 68,354,980 total letters Score E Sequences producing significant alignments: (bits) Value sp|Q99020|ROAA_MOUSE Heterogeneous nuclear ribonucleoprotei... 95 2e-19 sp|Q14103|HNRPD_HUMAN Heterogeneous nuclear ribonucleoprote... 92 2e-18 sp|P17132|HNRPC_RAT Heterogeneous nuclear ribonucleoprotein... 92 2e-18 sp|Q9JJ54|HNRPD_RAT Heterogeneous nuclear ribonucleoprotein... 92 2e-18 sp|Q60668|HNRPD_MOUSE Heterogeneous nuclear ribonucleoprote... 92 2e-18 sp|Q99729|ROAA_HUMAN Heterogeneous nuclear ribonucleoprotei... 87 6e-17 sp|P07029|HNRU2_HUMAN Heterogeneous nuclear ribonucleoprote... 82 1e-15 sp|Q08473|SQD_DROME RNA-binding protein squid (Heterogeneou... 82 2e-15 sp|Q920Q6|MSI2H_MOUSE RNA-binding protein Musashi homolog 2... 67 5e-11 sp|Q96DH6|MSI2H_HUMAN RNA-binding protein Musashi homolog 2... 67 5e-11
>sp|Q99020|ROAA_MOUSE Heterogeneous nuclear ribonucleoprotein A/B (hnRNP A/B) (CArG-binding factor-A) (CBF-A) Length = 285 Score = 95.1 bits (235), Expect = 2e-19 Identities = 46/96 (47%), Positives = 64/96 (66%), Gaps = 1/96 (1%) Frame = +2 Query: 2 LEVPEHRLKNKKIDPKPAKPTK-EPNKKIFVGGLSPDVTEEQIKEYFSQYGSVESVDLPF 178 L+ EHRL + IDPK A K +P KKIFVGGL+P+ TEE+I+EYF Q+G +E+++LP Sbjct: 133 LDQKEHRLDGRVIDPKKAMAMKKDPVKKIFVGGLNPEATEEKIREYFGQFGEIEAIELPI 192 Query: 179 DTSKGKRKPYVFLSFTTEDAAKNAIINEKQDVLGSK 286 D KR+ +VF++F ED K + + V GSK Sbjct: 193 DPKLNKRRGFVFITFKEEDPVKKVLEKKFHTVSGSK 228
Score = 48.9 bits (115), Expect = 2e-05 Identities = 22/82 (26%), Positives = 49/82 (59%) Frame = +2 Query: 53 AKPTKEPNKKIFVGGLSPDVTEEQIKEYFSQYGSVESVDLPFDTSKGKRKPYVFLSFTTE 232 A +E K+FVGGLS D +++ +K+YF+++G V + D + G+ + + F+ F + Sbjct: 67 ASKNEEDAGKMFVGGLSWDTSKKDLKDYFTKFGEVVDCTIKMDPNTGRSRGFGFILF-KD 125 Query: 233 DAAKNAIINEKQDVLGSKLVCP 298 ++ ++++K+ L +++ P Sbjct: 126 SSSVEKVLDQKEHRLDGRVIDP 147
>sp|Q14103|HNRPD_HUMAN Heterogeneous nuclear ribonucleoprotein D0 (hnRNP D0) (AU-rich element RNA-binding protein 1) Length = 355 Score = 92.0 bits (227), Expect = 2e-18 Identities = 47/97 (48%), Positives = 63/97 (64%), Gaps = 2/97 (2%) Frame = +2 Query: 2 LEVPEHRLKNKKIDPKPAKP--TKEPNKKIFVGGLSPDVTEEQIKEYFSQYGSVESVDLP 175 ++ EH+L K IDPK AK TKEP KKIFVGGLSPD EE+I+EYF +G VES++LP Sbjct: 155 MDQKEHKLNGKVIDPKRAKAMKTKEPVKKIFVGGLSPDTPEEKIREYFGGFGEVESIELP 214 Query: 176 FDTSKGKRKPYVFLSFTTEDAAKNAIINEKQDVLGSK 286 D KR+ + F++F E+ K + + +V SK Sbjct: 215 MDNKTNKRRGFCFITFKEEEPVKKIMEKKYHNVGLSK 251
Score = 51.2 bits (121), Expect = 4e-06 Identities = 24/73 (32%), Positives = 45/73 (61%) Frame = +2 Query: 80 KIFVGGLSPDVTEEQIKEYFSQYGSVESVDLPFDTSKGKRKPYVFLSFTTEDAAKNAIIN 259 K+F+GGLS D T++ +K+YFS++G V L D G+ + + F+ F E + + +++ Sbjct: 98 KMFIGGLSWDTTKKDLKDYFSKFGEVVDCTLKLDPITGRSRGFGFVLF-KESESVDKVMD 156 Query: 260 EKQDVLGSKLVCP 298 +K+ L K++ P Sbjct: 157 QKEHKLNGKVIDP 169
>sp|P17132|HNRPC_RAT Heterogeneous nuclear ribonucleoprotein C (hnRNP C) (hnRNP core protein C) Length = 158 Score = 92.0 bits (227), Expect = 2e-18 Identities = 47/97 (48%), Positives = 63/97 (64%), Gaps = 2/97 (2%) Frame = +2 Query: 2 LEVPEHRLKNKKIDPKPAKP--TKEPNKKIFVGGLSPDVTEEQIKEYFSQYGSVESVDLP 175 ++ EH+L K IDPK AK TKEP KKIFVGGLSPD EE+I+EYF +G VES++LP Sbjct: 7 MDQKEHKLNGKVIDPKRAKAMKTKEPVKKIFVGGLSPDTPEEKIREYFGGFGEVESIELP 66 Query: 176 FDTSKGKRKPYVFLSFTTEDAAKNAIINEKQDVLGSK 286 D KR+ + F++F E+ K + + +V SK Sbjct: 67 MDNKTNKRRGFCFITFKEEEPVKKIMEKKYHNVGLSK 103
>sp|Q9JJ54|HNRPD_RAT Heterogeneous nuclear ribonucleoprotein D0 (hnRNP D0) (AU-rich element RNA-binding protein 1) Length = 353 Score = 92.0 bits (227), Expect = 2e-18 Identities = 47/97 (48%), Positives = 63/97 (64%), Gaps = 2/97 (2%) Frame = +2 Query: 2 LEVPEHRLKNKKIDPKPAKP--TKEPNKKIFVGGLSPDVTEEQIKEYFSQYGSVESVDLP 175 ++ EH+L K IDPK AK TKEP KKIFVGGLSPD EE+I+EYF +G VES++LP Sbjct: 153 MDQKEHKLNGKVIDPKRAKAMKTKEPVKKIFVGGLSPDTPEEKIREYFGGFGEVESIELP 212 Query: 176 FDTSKGKRKPYVFLSFTTEDAAKNAIINEKQDVLGSK 286 D KR+ + F++F E+ K + + +V SK Sbjct: 213 MDNKTNKRRGFCFITFKEEEPVKKIMEKKYHNVGLSK 249
Score = 51.2 bits (121), Expect = 4e-06 Identities = 24/73 (32%), Positives = 45/73 (61%) Frame = +2 Query: 80 KIFVGGLSPDVTEEQIKEYFSQYGSVESVDLPFDTSKGKRKPYVFLSFTTEDAAKNAIIN 259 K+F+GGLS D T++ +K+YFS++G V L D G+ + + F+ F E + + +++ Sbjct: 96 KMFIGGLSWDTTKKDLKDYFSKFGDVVDCTLKLDPITGRSRGFGFVLF-KESESVDKVMD 154 Query: 260 EKQDVLGSKLVCP 298 +K+ L K++ P Sbjct: 155 QKEHKLNGKVIDP 167
>sp|Q60668|HNRPD_MOUSE Heterogeneous nuclear ribonucleoprotein D0 (hnRNP D0) (AU-rich element RNA-binding protein 1) Length = 355 Score = 92.0 bits (227), Expect = 2e-18 Identities = 47/97 (48%), Positives = 63/97 (64%), Gaps = 2/97 (2%) Frame = +2 Query: 2 LEVPEHRLKNKKIDPKPAKP--TKEPNKKIFVGGLSPDVTEEQIKEYFSQYGSVESVDLP 175 ++ EH+L K IDPK AK TKEP KKIFVGGLSPD EE+I+EYF +G VES++LP Sbjct: 155 MDQKEHKLNGKVIDPKRAKAMKTKEPVKKIFVGGLSPDTPEEKIREYFGGFGEVESIELP 214 Query: 176 FDTSKGKRKPYVFLSFTTEDAAKNAIINEKQDVLGSK 286 D KR+ + F++F E+ K + + +V SK Sbjct: 215 MDNKTNKRRGFCFITFKEEEPVKKIMEKKYHNVGLSK 251
Score = 51.2 bits (121), Expect = 4e-06 Identities = 24/73 (32%), Positives = 45/73 (61%) Frame = +2 Query: 80 KIFVGGLSPDVTEEQIKEYFSQYGSVESVDLPFDTSKGKRKPYVFLSFTTEDAAKNAIIN 259 K+F+GGLS D T++ +K+YFS++G V L D G+ + + F+ F E + + +++ Sbjct: 98 KMFIGGLSWDTTKKDLKDYFSKFGEVVDCTLKLDPITGRSRGFGFVLF-KESESVDKVMD 156 Query: 260 EKQDVLGSKLVCP 298 +K+ L K++ P Sbjct: 157 QKEHKLNGKVIDP 169
>sp|Q99729|ROAA_HUMAN Heterogeneous nuclear ribonucleoprotein A/B (hnRNP A/B) (APOBEC-1 binding protein 1) (ABBP-1) Length = 331 Score = 87.0 bits (214), Expect = 6e-17 Identities = 44/97 (45%), Positives = 64/97 (65%), Gaps = 2/97 (2%) Frame = +2 Query: 2 LEVPEHRLKNKKIDPKPAKPTK-EPNKKIFVGGLSPDV-TEEQIKEYFSQYGSVESVDLP 175 L+ EHRL + IDPK A K +P KKIFVGGL+P+ TEE+I+EYF ++G +E+++LP Sbjct: 126 LDQKEHRLDGRVIDPKKAMAMKKDPVKKIFVGGLNPESPTEEKIREYFGEFGEIEAIELP 185 Query: 176 FDTSKGKRKPYVFLSFTTEDAAKNAIINEKQDVLGSK 286 D KR+ +VF++F E+ K + + V GSK Sbjct: 186 MDPKLNKRRGFVFITFKEEEPVKKVLEKKFHTVSGSK 222
Score = 50.1 bits (118), Expect = 8e-06 Identities = 25/96 (26%), Positives = 53/96 (55%) Frame = +2 Query: 11 PEHRLKNKKIDPKPAKPTKEPNKKIFVGGLSPDVTEEQIKEYFSQYGSVESVDLPFDTSK 190 P ++ D A +E K+FVGGLS D +++ +K+YF+++G V + D + Sbjct: 46 PRAGIRTAPRDQINASKNEEDAGKMFVGGLSWDTSKKDLKDYFTKFGEVVDCTIKMDPNT 105 Query: 191 GKRKPYVFLSFTTEDAAKNAIINEKQDVLGSKLVCP 298 G+ + + F+ F + A+ ++++K+ L +++ P Sbjct: 106 GRSRGFGFILF-KDAASVEKVLDQKEHRLDGRVIDP 140
>sp|P07029|HNRU2_HUMAN Heterogeneous nuclear ribonucleoprotein UP2 Length = 225 Score = 82.4 bits (202), Expect = 1e-15 Identities = 40/70 (57%), Positives = 50/70 (71%), Gaps = 2/70 (2%) Frame = +2 Query: 32 KKIDPKPAKP--TKEPNKKIFVGGLSPDVTEEQIKEYFSQYGSVESVDLPFDTSKGKRKP 205 K IDPK AK TKEP KKIFVGGLSPD EE+I+EYF +G VES++LP D KR+ Sbjct: 155 KVIDPKRAKAMKTKEPVKKIFVGGLSPDTPEEKIREYFGGFGEVESIELPMDNKTNKRRG 214 Query: 206 YVFLSFTTED 235 + F++F E+ Sbjct: 215 FCFITFNQEE 224
>sp|Q08473|SQD_DROME RNA-binding protein squid (Heterogeneous nuclear ribonucleoprotein 40) (HNRNP 40) Length = 344 Score = 81.6 bits (200), Expect = 2e-15 Identities = 36/92 (39%), Positives = 61/92 (66%) Frame = +2 Query: 14 EHRLKNKKIDPKPAKPTKEPNKKIFVGGLSPDVTEEQIKEYFSQYGSVESVDLPFDTSKG 193 EH + +KK+DPK AK + KIFVGGL+ ++++E+IK YF Q+G++ V++PFD K Sbjct: 118 EHIINSKKVDPKKAKAR---HGKIFVGGLTTEISDEEIKTYFGQFGNIVEVEMPFDKQKS 174 Query: 194 KRKPYVFLSFTTEDAAKNAIINEKQDVLGSKL 289 +RK + F++F +E + + KQ + G ++ Sbjct: 175 QRKGFCFITFDSEQVVTDLLKTPKQKIAGKEV 206
Score = 57.8 bits (138), Expect = 4e-08 Identities = 25/82 (30%), Positives = 52/82 (63%) Frame = +2 Query: 53 AKPTKEPNKKIFVGGLSPDVTEEQIKEYFSQYGSVESVDLPFDTSKGKRKPYVFLSFTTE 232 A ++ ++K+FVGGLS + TE++++++F +YG +ES+++ D G+ + + F+ FT Sbjct: 48 ASGQRDDDRKLFVGGLSWETTEKELRDHFGKYGEIESINVKTDPQTGRSRGFAFIVFTNT 107 Query: 233 DAAKNAIINEKQDVLGSKLVCP 298 +A + + + ++ SK V P Sbjct: 108 EAI-DKVSAADEHIINSKKVDP 128
>sp|Q920Q6|MSI2H_MOUSE RNA-binding protein Musashi homolog 2 (Musashi-2) Length = 346 Score = 67.4 bits (163), Expect = 5e-11 Identities = 34/84 (40%), Positives = 47/84 (55%), Gaps = 6/84 (7%) Frame = +2 Query: 11 PEHRLKNKKIDPKPAKPTKEP------NKKIFVGGLSPDVTEEQIKEYFSQYGSVESVDL 172 P H L +K IDPK A P + KKIFVGGLS + E +K+YF Q+G VE L Sbjct: 82 PHHELDSKTIDPKVAFPRRAQPKMVTRTKKIFVGGLSANTVVEDVKQYFEQFGKVEDAML 141 Query: 173 PFDTSKGKRKPYVFLSFTTEDAAK 244 FD + + + + F++F ED + Sbjct: 142 MFDKTTNRHRGFGFVTFENEDVVE 165
Score = 40.0 bits (92), Expect = 0.008 Identities = 18/73 (24%), Positives = 42/73 (57%) Frame = +2 Query: 80 KIFVGGLSPDVTEEQIKEYFSQYGSVESVDLPFDTSKGKRKPYVFLSFTTEDAAKNAIIN 259 K+F+GGLS + + +++YFS++G + + D + + + + F++F + A+ + ++ Sbjct: 22 KMFIGGLSWQTSPDSLRDYFSKFGEIRECMVMRDPTTKRSRGFGFVTF-ADPASVDKVLG 80 Query: 260 EKQDVLGSKLVCP 298 + L SK + P Sbjct: 81 QPHHELDSKTIDP 93
>sp|Q96DH6|MSI2H_HUMAN RNA-binding protein Musashi homolog 2 (Musashi-2) Length = 328 Score = 67.4 bits (163), Expect = 5e-11 Identities = 34/84 (40%), Positives = 47/84 (55%), Gaps = 6/84 (7%) Frame = +2 Query: 11 PEHRLKNKKIDPKPAKPTKEP------NKKIFVGGLSPDVTEEQIKEYFSQYGSVESVDL 172 P H L +K IDPK A P + KKIFVGGLS + E +K+YF Q+G VE L Sbjct: 82 PHHELDSKTIDPKVAFPRRAQPKMVTRTKKIFVGGLSANTVVEDVKQYFEQFGKVEDAML 141 Query: 173 PFDTSKGKRKPYVFLSFTTEDAAK 244 FD + + + + F++F ED + Sbjct: 142 MFDKTTNRHRGFGFVTFENEDVVE 165
Score = 40.0 bits (92), Expect = 0.008 Identities = 18/73 (24%), Positives = 42/73 (57%) Frame = +2 Query: 80 KIFVGGLSPDVTEEQIKEYFSQYGSVESVDLPFDTSKGKRKPYVFLSFTTEDAAKNAIIN 259 K+F+GGLS + + +++YFS++G + + D + + + + F++F + A+ + ++ Sbjct: 22 KMFIGGLSWQTSPDSLRDYFSKFGEIRECMVMRDPTTKRSRGFGFVTF-ADPASVDKVLG 80 Query: 260 EKQDVLGSKLVCP 298 + L SK + P Sbjct: 81 QPHHELDSKTIDP 93
Database: Non-redundant SwissProt sequences Posted date: Dec 6, 2005 7:40 AM Number of letters in database: 68,354,980 Number of sequences in database: 184,735 Database: swissprot.01 Posted date: Dec 6, 2005 8:18 AM Number of letters in database: 66,202,850 Number of sequences in database: 184,431 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 89,565,011 Number of Sequences: 369166 Number of extensions: 1757531 Number of successful extensions: 5299 Number of sequences better than 10.0: 10 Number of HSP's better than 10.0 without gapping: 4997 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 5275 length of database: 68,354,980 effective HSP length: 109 effective length of database: 48,218,865 effective search space used: 8438301375 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)