Planaria EST Database

DrC_00626

BLASTX 2.2.13 [Nov-27-2005]

Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= DrC_00626
         (386 letters)

Database: Non-redundant SwissProt sequences 
           184,735 sequences; 68,354,980 total letters



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

sp|P81015|GRN3_CYPCA  Granulin-3                                   61   7e-10
sp|P81014|GRN2_CYPCA  Granulin-2                                   61   7e-10
sp|P81013|GRN1_CYPCA  Granulin-1                                   59   3e-09
sp|P28798|GRN_MOUSE  Granulins precursor (Acrogranin) (Proep...    57   2e-08
sp|P28797|GRN_CAVPO  Granulins precursor (Proepithelin) (PEP...    55   5e-08
sp|P23785|GRN_RAT  Granulins precursor [Contains: Acrogranin...    55   5e-08
sp|P28799|GRN_HUMAN  Granulins precursor (Proepithelin) (PEP...    54   8e-08
sp|P80059|PMD1_LOCMI  Pars intercerebralis major peptide D1 ...    54   1e-07
sp|P80930|ENA1_HORSE  Antimicrobial peptide eNAP-1                 50   2e-06
sp|P43297|RD21A_ARATH  Cysteine proteinase RD21a precursor (...    44   1e-04

>sp|P81015|GRN3_CYPCA Granulin-3
          Length = 57

 Score = 61.2 bits (147), Expect = 7e-10
 Identities = 25/48 (52%), Positives = 28/48 (58%)
 Frame = +2

Query: 116 CPDGNRCPGYQTCCLSYTGHFGCCPFQLGVCCPGGRTCCRHGQRCVSS 259
           C  G  CP   TCC S  G + CCPF +G CC  GR CCRHG  C S+
Sbjct: 4   CDAGITCPSGTTCCRSPFGVWYCCPFLMGQCCRDGRHCCRHGYHCDST 51

>sp|P81014|GRN2_CYPCA Granulin-2
          Length = 57

 Score = 61.2 bits (147), Expect = 7e-10
 Identities = 25/48 (52%), Positives = 28/48 (58%)
 Frame = +2

Query: 116 CPDGNRCPGYQTCCLSYTGHFGCCPFQLGVCCPGGRTCCRHGQRCVSS 259
           C     CP   TCC S  G + CCPF +G CC  GR CCRHG RC S+
Sbjct: 4   CNARTTCPSRTTCCRSPFGVWYCCPFLMGQCCRDGRHCCRHGYRCDST 51

>sp|P81013|GRN1_CYPCA Granulin-1
          Length = 57

 Score = 59.3 bits (142), Expect = 3e-09
 Identities = 26/49 (53%), Positives = 29/49 (59%)
 Frame = +2

Query: 113 ICPDGNRCPGYQTCCLSYTGHFGCCPFQLGVCCPGGRTCCRHGQRCVSS 259
           ICPDG       TCCLS  G + CCPF +G CC  G  CCRHG  C S+
Sbjct: 9   ICPDGT------TCCLSPYGVWYCCPFSMGQCCRDGIHCCRHGYHCDST 51

>sp|P28798|GRN_MOUSE Granulins precursor (Acrogranin) (Proepithelin) (PEPI) (PC
           cell-derived growth factor) (PCDGF) [Contains: Granulin
           1; Granulin 2; Granulin 3; Granulin 4; Granulin 5;
           Granulin 6; Granulin 7]
          Length = 589

 Score = 56.6 bits (135), Expect = 2e-08
 Identities = 25/56 (44%), Positives = 31/56 (55%)
 Frame = +2

Query: 95  KLGNKYICPDGNRCPGYQTCCLSYTGHFGCCPFQLGVCCPGGRTCCRHGQRCVSSG 262
           K+GN   C +G+ C   QTCC    G + CCP+  GVCC  GR CC  G  C + G
Sbjct: 511 KVGNVE-CGEGHFCHDNQTCCKDSAGVWACCPYLKGVCCRDGRHCCPGGFHCSARG 565


 Score = 55.8 bits (133), Expect = 3e-08
 Identities = 21/49 (42%), Positives = 26/49 (53%)
 Frame = +2

Query: 116 CPDGNRCPGYQTCCLSYTGHFGCCPFQLGVCCPGGRTCCRHGQRCVSSG 262
           C D  RCP   TCC   +G +GCCP    VCC   + CC  G  C++ G
Sbjct: 364 CDDFTRCPTNNTCCKLNSGDWGCCPIPEAVCCSDNQHCCPQGFTCLAQG 412


 Score = 49.3 bits (116), Expect = 3e-06
 Identities = 22/61 (36%), Positives = 28/61 (45%), Gaps = 3/61 (4%)
 Frame = +2

Query: 92  IKLGNKYICPDGN-RCPGYQTCCLSYTGHFGCCPFQLGVCCPGGRTCCRHGQRC--VSSG 262
           + L    +CPD   +CP   TCC   TG +GCCP    +CC     CC     C  + S 
Sbjct: 199 VSLPFSVVCPDAKTQCPDDSTCCELPTGKYGCCPMPNAICCSDHLHCCPQDTVCDLIQSK 258

Query: 263 C 265
           C
Sbjct: 259 C 259


 Score = 48.9 bits (115), Expect = 4e-06
 Identities = 19/46 (41%), Positives = 21/46 (45%), Gaps = 1/46 (2%)
 Frame = +2

Query: 116 CPDGN-RCPGYQTCCLSYTGHFGCCPFQLGVCCPGGRTCCRHGQRC 250
           CP     CP   TCC+   G +GCCP     CC     CC HG  C
Sbjct: 125 CPGSQFECPDSATCCIMVDGSWGCCPMPQASCCEDRVHCCPHGASC 170


 Score = 47.8 bits (112), Expect = 8e-06
 Identities = 19/49 (38%), Positives = 23/49 (46%)
 Frame = +2

Query: 116 CPDGNRCPGYQTCCLSYTGHFGCCPFQLGVCCPGGRTCCRHGQRCVSSG 262
           C     CP   +C L+ +G   CCPF  GV C  G  CC  G  C + G
Sbjct: 61  CQTHGHCPAGYSCLLTVSGTSSCCPFSKGVSCGDGYHCCPQGFHCSADG 109


 Score = 47.4 bits (111), Expect = 1e-05
 Identities = 19/39 (48%), Positives = 21/39 (53%)
 Frame = +2

Query: 134 CPGYQTCCLSYTGHFGCCPFQLGVCCPGGRTCCRHGQRC 250
           CP   TCC   TG +GCCPF   VCC     CC  G +C
Sbjct: 288 CPEGYTCCRLNTGAWGCCPFAKAVCCEDHIHCCPAGFQC 326


 Score = 45.1 bits (105), Expect = 5e-05
 Identities = 18/45 (40%), Positives = 20/45 (44%)
 Frame = +2

Query: 116 CPDGNRCPGYQTCCLSYTGHFGCCPFQLGVCCPGGRTCCRHGQRC 250
           C     CP  QTCC S  G + CC     VCC   + CC  G  C
Sbjct: 442 CDQHTSCPVGQTCCPSLKGSWACCQLPHAVCCEDRQHCCPAGYTC 486

>sp|P28797|GRN_CAVPO Granulins precursor (Proepithelin) (PEPI) [Contains: Acrogranin;
           Granulin-1; Granulin-2; Granulin-3; Granulin-4;
           Granulin-5; Granulin-6; Granulin-7]
          Length = 591

 Score = 55.1 bits (131), Expect = 5e-08
 Identities = 23/49 (46%), Positives = 25/49 (51%)
 Frame = +2

Query: 116 CPDGNRCPGYQTCCLSYTGHFGCCPFQLGVCCPGGRTCCRHGQRCVSSG 262
           C D + C   QTCC    G + CCPF  GVCC   R CC  G  C S G
Sbjct: 518 CGDRHFCHDEQTCCRDSRGGWACCPFHQGVCCKDQRHCCPAGFHCESQG 566


 Score = 51.2 bits (121), Expect = 7e-07
 Identities = 21/52 (40%), Positives = 26/52 (50%), Gaps = 1/52 (1%)
 Frame = +2

Query: 98  LGNKYICPDG-NRCPGYQTCCLSYTGHFGCCPFQLGVCCPGGRTCCRHGQRC 250
           L    ICPD  ++CP   TCCL  +G +GCCP    +CC     CC     C
Sbjct: 202 LPTSVICPDSRSQCPDDTTCCLLASGEYGCCPMPNAICCSDHLHCCPQDTVC 253


 Score = 49.7 bits (117), Expect = 2e-06
 Identities = 20/46 (43%), Positives = 21/46 (45%), Gaps = 1/46 (2%)
 Frame = +2

Query: 116 CPDGN-RCPGYQTCCLSYTGHFGCCPFQLGVCCPGGRTCCRHGQRC 250
           CP G   CP   TCC    G +GCCP     CC     CC HG  C
Sbjct: 112 CPGGEFECPDSSTCCHMLDGSWGCCPMPQASCCEDRVHCCPHGASC 157


 Score = 48.9 bits (115), Expect = 4e-06
 Identities = 20/45 (44%), Positives = 22/45 (48%)
 Frame = +2

Query: 116 CPDGNRCPGYQTCCLSYTGHFGCCPFQLGVCCPGGRTCCRHGQRC 250
           C     CP  QTCC   +G +GCCPF   VCC     CC    RC
Sbjct: 283 CDQEVSCPEGQTCCRLQSGKWGCCPFPKAVCCEDHVHCCPERFRC 327


 Score = 45.4 bits (106), Expect = 4e-05
 Identities = 18/45 (40%), Positives = 20/45 (44%)
 Frame = +2

Query: 116 CPDGNRCPGYQTCCLSYTGHFGCCPFQLGVCCPGGRTCCRHGQRC 250
           C     CP  QTCC    G + CC     VCC  G+ CC  G  C
Sbjct: 441 CDQHASCPVRQTCCPKLGGGWACCQLPHAVCCEDGQHCCPAGYTC 485


 Score = 43.9 bits (102), Expect = 1e-04
 Identities = 17/49 (34%), Positives = 22/49 (44%)
 Frame = +2

Query: 116 CPDGNRCPGYQTCCLSYTGHFGCCPFQLGVCCPGGRTCCRHGQRCVSSG 262
           C     CP   +C L+  G   CCPF   + C  G  CC +G  C + G
Sbjct: 47  CQSPANCPIGHSCVLTAAGTAACCPFSQAMACGDGHHCCPYGFHCSTDG 95


 Score = 33.9 bits (76), Expect = 0.12
 Identities = 14/44 (31%), Positives = 19/44 (43%)
 Frame = +2

Query: 98  LGNKYICPDGNRCPGYQTCCLSYTGHFGCCPFQLGVCCPGGRTC 229
           L ++  C +   C     CC   +G +GCCP   G  C  G  C
Sbjct: 372 LRSEISCDEVVSCRPGNICCRLASGEWGCCPSSEGYLCMAGERC 415

>sp|P23785|GRN_RAT Granulins precursor [Contains: Acrogranin; Granulin-1 (Granulin G);
           Granulin-2 (Granulin F); Granulin-3 (Granulin B)
           (Epithelin-2); Granulin-4 (Granulin A) (Epithelin-1);
           Granulin-5 (Granulin C); Granulin-6 (Granulin D);
           Granulin-7 (Granulin E)]
          Length = 588

 Score = 55.1 bits (131), Expect = 5e-08
 Identities = 22/55 (40%), Positives = 28/55 (50%)
 Frame = +2

Query: 98  LGNKYICPDGNRCPGYQTCCLSYTGHFGCCPFQLGVCCPGGRTCCRHGQRCVSSG 262
           L N   C D + CP   TCC   +G +GCCP    VCC   + CC  G +C+  G
Sbjct: 357 LKNDVPCDDFSSCPSNNTCCRLSSGDWGCCPMPEAVCCLDHQHCCPQGFKCMDEG 411


 Score = 53.5 bits (127), Expect = 1e-07
 Identities = 24/56 (42%), Positives = 30/56 (53%)
 Frame = +2

Query: 95  KLGNKYICPDGNRCPGYQTCCLSYTGHFGCCPFQLGVCCPGGRTCCRHGQRCVSSG 262
           K+GN   C  G+ C   Q+CC    G + CCP+  GVCC  GR CC  G  C + G
Sbjct: 510 KVGNVE-CGAGHFCHDNQSCCKDSQGGWACCPYVKGVCCRDGRHCCPIGFHCSAKG 564


 Score = 50.1 bits (118), Expect = 2e-06
 Identities = 25/59 (42%), Positives = 30/59 (50%)
 Frame = +2

Query: 74  PLNELLIKLGNKYICPDGNRCPGYQTCCLSYTGHFGCCPFQLGVCCPGGRTCCRHGQRC 250
           P+NE  +K   +  CPDG       TCC   TG +GCCPF   VCC     CC  G +C
Sbjct: 275 PVNE--VKCDLEVSCPDG------YTCCRLNTGAWGCCPFTKAVCCEDHIHCCPAGFQC 325


 Score = 48.9 bits (115), Expect = 4e-06
 Identities = 19/46 (41%), Positives = 21/46 (45%), Gaps = 1/46 (2%)
 Frame = +2

Query: 116 CPDGN-RCPGYQTCCLSYTGHFGCCPFQLGVCCPGGRTCCRHGQRC 250
           CP     CP   TCC+   G +GCCP     CC     CC HG  C
Sbjct: 125 CPGSQFECPDSATCCIMIDGSWGCCPMPQASCCEDRVHCCPHGASC 170


 Score = 48.9 bits (115), Expect = 4e-06
 Identities = 21/54 (38%), Positives = 26/54 (48%), Gaps = 3/54 (5%)
 Frame = +2

Query: 113 ICPDGN-RCPGYQTCCLSYTGHFGCCPFQLGVCCPGGRTCCRHGQRC--VSSGC 265
           +CPD   +CP   TCC   TG +GCCP    +CC     CC     C  + S C
Sbjct: 205 VCPDAKTQCPDDSTCCELPTGKYGCCPMPNAICCSDHLHCCPQDTVCDLIQSKC 258


 Score = 48.1 bits (113), Expect = 6e-06
 Identities = 19/49 (38%), Positives = 25/49 (51%)
 Frame = +2

Query: 116 CPDGNRCPGYQTCCLSYTGHFGCCPFQLGVCCPGGRTCCRHGQRCVSSG 262
           C   + CP   +C L+ +G   CCPF  GV C  G+ CC  G  C + G
Sbjct: 61  CQIRDHCPDGYSCLLTVSGTSSCCPFSEGVSCDDGQHCCPRGFHCSADG 109


 Score = 47.0 bits (110), Expect = 1e-05
 Identities = 20/63 (31%), Positives = 27/63 (42%)
 Frame = +2

Query: 62  VERKPLNELLIKLGNKYICPDGNRCPGYQTCCLSYTGHFGCCPFQLGVCCPGGRTCCRHG 241
           +E+ P+ +  +       C     CP  QTCC S  G + CC     VCC   + CC  G
Sbjct: 423 LEKMPVRQTTLLQHGDIGCDQHTSCPVGQTCCPSLKGSWACCQLPHAVCCEDRQHCCPAG 482

Query: 242 QRC 250
             C
Sbjct: 483 YTC 485

>sp|P28799|GRN_HUMAN Granulins precursor (Proepithelin) (PEPI) [Contains: Acrogranin;
           Paragranulin; Granulin-1 (Granulin G); Granulin-2
           (Granulin F); Granulin-3 (Granulin B); Granulin-4
           (Granulin A); Granulin-5 (Granulin C); Granulin-6
           (Granulin D); Granulin-7 (Granulin E)]
          Length = 593

 Score = 54.3 bits (129), Expect = 8e-08
 Identities = 20/49 (40%), Positives = 26/49 (53%)
 Frame = +2

Query: 116 CPDGNRCPGYQTCCLSYTGHFGCCPFQLGVCCPGGRTCCRHGQRCVSSG 262
           C + + CP   TCC   +G +GCCP    VCC   + CC  G  CV+ G
Sbjct: 366 CDNVSSCPSSDTCCQLTSGEWGCCPIPEAVCCSDHQHCCPQGYTCVAEG 414


 Score = 53.9 bits (128), Expect = 1e-07
 Identities = 21/49 (42%), Positives = 27/49 (55%)
 Frame = +2

Query: 116 CPDGNRCPGYQTCCLSYTGHFGCCPFQLGVCCPGGRTCCRHGQRCVSSG 262
           C +G+ C   QTCC      + CCP++ GVCC   R CC  G RC + G
Sbjct: 521 CGEGHFCHDNQTCCRDNRQGWACCPYRQGVCCADRRHCCPAGFRCAARG 569


 Score = 52.8 bits (125), Expect = 2e-07
 Identities = 20/46 (43%), Positives = 23/46 (50%), Gaps = 1/46 (2%)
 Frame = +2

Query: 116 CPDGN-RCPGYQTCCLSYTGHFGCCPFQLGVCCPGGRTCCRHGQRC 250
           CPD    CP + TCC+   G +GCCP     CC     CC HG  C
Sbjct: 126 CPDSQFECPDFSTCCVMVDGSWGCCPMPQASCCEDRVHCCPHGAFC 171


 Score = 49.7 bits (117), Expect = 2e-06
 Identities = 22/61 (36%), Positives = 29/61 (47%), Gaps = 3/61 (4%)
 Frame = +2

Query: 92  IKLGNKYICPDG-NRCPGYQTCCLSYTGHFGCCPFQLGVCCPGGRTCCRHGQRC--VSSG 262
           + L +  +CPD  +RCP   TCC   +G +GCCP     CC     CC     C  + S 
Sbjct: 200 VALSSSVMCPDARSRCPDGSTCCELPSGKYGCCPMPNATCCSDHLHCCPQDTVCDLIQSK 259

Query: 263 C 265
           C
Sbjct: 260 C 260


 Score = 46.2 bits (108), Expect = 2e-05
 Identities = 21/53 (39%), Positives = 25/53 (47%)
 Frame = +2

Query: 92  IKLGNKYICPDGNRCPGYQTCCLSYTGHFGCCPFQLGVCCPGGRTCCRHGQRC 250
           +K   +  CPDG       TCC   +G +GCCPF   VCC     CC  G  C
Sbjct: 282 VKCDMEVSCPDG------YTCCRLQSGAWGCCPFTQAVCCEDHIHCCPAGFTC 328


 Score = 45.1 bits (105), Expect = 5e-05
 Identities = 20/63 (31%), Positives = 25/63 (39%)
 Frame = +2

Query: 62  VERKPLNELLIKLGNKYICPDGNRCPGYQTCCLSYTGHFGCCPFQLGVCCPGGRTCCRHG 241
           +E+ P     +       C     CP  QTCC S  G + CC     VCC   + CC  G
Sbjct: 426 LEKMPARRASLSHPRDIGCDQHTSCPVGQTCCPSLGGSWACCQLPHAVCCEDRQHCCPAG 485

Query: 242 QRC 250
             C
Sbjct: 486 YTC 488


 Score = 40.4 bits (93), Expect = 0.001
 Identities = 16/49 (32%), Positives = 20/49 (40%)
 Frame = +2

Query: 116 CPDGNRCPGYQTCCLSYTGHFGCCPFQLGVCCPGGRTCCRHGQRCVSSG 262
           C     C    +C  + +G   CCPF   V C  G  CC  G  C + G
Sbjct: 61  CQVDAHCSAGHSCIFTVSGTSSCCPFPEAVACGDGHHCCPRGFHCSADG 109

>sp|P80059|PMD1_LOCMI Pars intercerebralis major peptide D1 (PMP-D1)
          Length = 54

 Score = 53.5 bits (127), Expect = 1e-07
 Identities = 20/39 (51%), Positives = 24/39 (61%)
 Frame = +2

Query: 134 CPGYQTCCLSYTGHFGCCPFQLGVCCPGGRTCCRHGQRC 250
           CPG +TCC +  G  GCCP++ GVCC  G  CC  G  C
Sbjct: 7   CPGTETCCTTPQGEEGCCPYKEGVCCLDGIHCCPSGTVC 45

>sp|P80930|ENA1_HORSE Antimicrobial peptide eNAP-1
          Length = 46

 Score = 49.7 bits (117), Expect = 2e-06
 Identities = 19/42 (45%), Positives = 23/42 (54%)
 Frame = +2

Query: 116 CPDGNRCPGYQTCCLSYTGHFGCCPFQLGVCCPGGRTCCRHG 241
           C +G+ C   QTCC +  G   CCP+  GVCC   R CC  G
Sbjct: 4   CGEGHFCHDXQTCCRASQGGXACCPYSQGVCCADQRHCCPVG 45

>sp|P43297|RD21A_ARATH Cysteine proteinase RD21a precursor (RD21)
          Length = 462

 Score = 43.9 bits (102), Expect = 1e-04
 Identities = 18/47 (38%), Positives = 22/47 (46%), Gaps = 4/47 (8%)
 Frame = +2

Query: 110 YICPDGNRCPGYQTCCLSYTGHF----GCCPFQLGVCCPGGRTCCRH 238
           Y CP+ N C     CCL   G +    GCCP +   CC    +CC H
Sbjct: 379 YTCPESNTC-----CCLFEYGKYCFAWGCCPLEAATCCDDNYSCCPH 420

  Database: Non-redundant SwissProt sequences
    Posted date:  Dec 6, 2005  7:40 AM
  Number of letters in database: 68,354,980
  Number of sequences in database:  184,735
  
  Database: swissprot.01
    Posted date:  Dec 6, 2005  8:18 AM
  Number of letters in database: 66,202,850
  Number of sequences in database:  184,431
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 41,735,117
Number of Sequences: 369166
Number of extensions: 874655
Number of successful extensions: 2622
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 2423
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 2593
length of database: 68,354,980
effective HSP length: 95
effective length of database: 50,805,155
effective search space used: 1676570115
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)

Cluster detail

DrC_00626

  1. Dr_sW_016_J20
  2. Dr_sW_003_G01
  3. Dr_sW_019_J17