Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_016_J20
(386 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P81015|GRN3_CYPCA Granulin-3 61 7e-10
sp|P81014|GRN2_CYPCA Granulin-2 61 7e-10
sp|P81013|GRN1_CYPCA Granulin-1 59 3e-09
sp|P28798|GRN_MOUSE Granulins precursor (Acrogranin) (Proep... 57 2e-08
sp|P28797|GRN_CAVPO Granulins precursor (Proepithelin) (PEP... 55 5e-08
sp|P23785|GRN_RAT Granulins precursor [Contains: Acrogranin... 55 5e-08
sp|P28799|GRN_HUMAN Granulins precursor (Proepithelin) (PEP... 54 8e-08
sp|P80059|PMD1_LOCMI Pars intercerebralis major peptide D1 ... 54 1e-07
sp|P80930|ENA1_HORSE Antimicrobial peptide eNAP-1 50 2e-06
sp|P43297|RD21A_ARATH Cysteine proteinase RD21a precursor (... 44 1e-04
>sp|P81015|GRN3_CYPCA Granulin-3
Length = 57
Score = 61.2 bits (147), Expect = 7e-10
Identities = 25/48 (52%), Positives = 28/48 (58%)
Frame = +2
Query: 116 CPDGNRCPGYQTCCLSYTGHFGCCPFQLGVCCPGGRTCCRHGQRCVSS 259
C G CP TCC S G + CCPF +G CC GR CCRHG C S+
Sbjct: 4 CDAGITCPSGTTCCRSPFGVWYCCPFLMGQCCRDGRHCCRHGYHCDST 51
>sp|P81014|GRN2_CYPCA Granulin-2
Length = 57
Score = 61.2 bits (147), Expect = 7e-10
Identities = 25/48 (52%), Positives = 28/48 (58%)
Frame = +2
Query: 116 CPDGNRCPGYQTCCLSYTGHFGCCPFQLGVCCPGGRTCCRHGQRCVSS 259
C CP TCC S G + CCPF +G CC GR CCRHG RC S+
Sbjct: 4 CNARTTCPSRTTCCRSPFGVWYCCPFLMGQCCRDGRHCCRHGYRCDST 51
>sp|P81013|GRN1_CYPCA Granulin-1
Length = 57
Score = 59.3 bits (142), Expect = 3e-09
Identities = 26/49 (53%), Positives = 29/49 (59%)
Frame = +2
Query: 113 ICPDGNRCPGYQTCCLSYTGHFGCCPFQLGVCCPGGRTCCRHGQRCVSS 259
ICPDG TCCLS G + CCPF +G CC G CCRHG C S+
Sbjct: 9 ICPDGT------TCCLSPYGVWYCCPFSMGQCCRDGIHCCRHGYHCDST 51
>sp|P28798|GRN_MOUSE Granulins precursor (Acrogranin) (Proepithelin) (PEPI) (PC
cell-derived growth factor) (PCDGF) [Contains: Granulin
1; Granulin 2; Granulin 3; Granulin 4; Granulin 5;
Granulin 6; Granulin 7]
Length = 589
Score = 56.6 bits (135), Expect = 2e-08
Identities = 25/56 (44%), Positives = 31/56 (55%)
Frame = +2
Query: 95 KLGNKYICPDGNRCPGYQTCCLSYTGHFGCCPFQLGVCCPGGRTCCRHGQRCVSSG 262
K+GN C +G+ C QTCC G + CCP+ GVCC GR CC G C + G
Sbjct: 511 KVGNVE-CGEGHFCHDNQTCCKDSAGVWACCPYLKGVCCRDGRHCCPGGFHCSARG 565
Score = 55.8 bits (133), Expect = 3e-08
Identities = 21/49 (42%), Positives = 26/49 (53%)
Frame = +2
Query: 116 CPDGNRCPGYQTCCLSYTGHFGCCPFQLGVCCPGGRTCCRHGQRCVSSG 262
C D RCP TCC +G +GCCP VCC + CC G C++ G
Sbjct: 364 CDDFTRCPTNNTCCKLNSGDWGCCPIPEAVCCSDNQHCCPQGFTCLAQG 412
Score = 49.3 bits (116), Expect = 3e-06
Identities = 22/61 (36%), Positives = 28/61 (45%), Gaps = 3/61 (4%)
Frame = +2
Query: 92 IKLGNKYICPDGN-RCPGYQTCCLSYTGHFGCCPFQLGVCCPGGRTCCRHGQRC--VSSG 262
+ L +CPD +CP TCC TG +GCCP +CC CC C + S
Sbjct: 199 VSLPFSVVCPDAKTQCPDDSTCCELPTGKYGCCPMPNAICCSDHLHCCPQDTVCDLIQSK 258
Query: 263 C 265
C
Sbjct: 259 C 259
Score = 48.9 bits (115), Expect = 4e-06
Identities = 19/46 (41%), Positives = 21/46 (45%), Gaps = 1/46 (2%)
Frame = +2
Query: 116 CPDGN-RCPGYQTCCLSYTGHFGCCPFQLGVCCPGGRTCCRHGQRC 250
CP CP TCC+ G +GCCP CC CC HG C
Sbjct: 125 CPGSQFECPDSATCCIMVDGSWGCCPMPQASCCEDRVHCCPHGASC 170
Score = 47.8 bits (112), Expect = 8e-06
Identities = 19/49 (38%), Positives = 23/49 (46%)
Frame = +2
Query: 116 CPDGNRCPGYQTCCLSYTGHFGCCPFQLGVCCPGGRTCCRHGQRCVSSG 262
C CP +C L+ +G CCPF GV C G CC G C + G
Sbjct: 61 CQTHGHCPAGYSCLLTVSGTSSCCPFSKGVSCGDGYHCCPQGFHCSADG 109
Score = 47.4 bits (111), Expect = 1e-05
Identities = 19/39 (48%), Positives = 21/39 (53%)
Frame = +2
Query: 134 CPGYQTCCLSYTGHFGCCPFQLGVCCPGGRTCCRHGQRC 250
CP TCC TG +GCCPF VCC CC G +C
Sbjct: 288 CPEGYTCCRLNTGAWGCCPFAKAVCCEDHIHCCPAGFQC 326
Score = 45.1 bits (105), Expect = 5e-05
Identities = 18/45 (40%), Positives = 20/45 (44%)
Frame = +2
Query: 116 CPDGNRCPGYQTCCLSYTGHFGCCPFQLGVCCPGGRTCCRHGQRC 250
C CP QTCC S G + CC VCC + CC G C
Sbjct: 442 CDQHTSCPVGQTCCPSLKGSWACCQLPHAVCCEDRQHCCPAGYTC 486
>sp|P28797|GRN_CAVPO Granulins precursor (Proepithelin) (PEPI) [Contains: Acrogranin;
Granulin-1; Granulin-2; Granulin-3; Granulin-4;
Granulin-5; Granulin-6; Granulin-7]
Length = 591
Score = 55.1 bits (131), Expect = 5e-08
Identities = 23/49 (46%), Positives = 25/49 (51%)
Frame = +2
Query: 116 CPDGNRCPGYQTCCLSYTGHFGCCPFQLGVCCPGGRTCCRHGQRCVSSG 262
C D + C QTCC G + CCPF GVCC R CC G C S G
Sbjct: 518 CGDRHFCHDEQTCCRDSRGGWACCPFHQGVCCKDQRHCCPAGFHCESQG 566
Score = 51.2 bits (121), Expect = 7e-07
Identities = 21/52 (40%), Positives = 26/52 (50%), Gaps = 1/52 (1%)
Frame = +2
Query: 98 LGNKYICPDG-NRCPGYQTCCLSYTGHFGCCPFQLGVCCPGGRTCCRHGQRC 250
L ICPD ++CP TCCL +G +GCCP +CC CC C
Sbjct: 202 LPTSVICPDSRSQCPDDTTCCLLASGEYGCCPMPNAICCSDHLHCCPQDTVC 253
Score = 49.7 bits (117), Expect = 2e-06
Identities = 20/46 (43%), Positives = 21/46 (45%), Gaps = 1/46 (2%)
Frame = +2
Query: 116 CPDGN-RCPGYQTCCLSYTGHFGCCPFQLGVCCPGGRTCCRHGQRC 250
CP G CP TCC G +GCCP CC CC HG C
Sbjct: 112 CPGGEFECPDSSTCCHMLDGSWGCCPMPQASCCEDRVHCCPHGASC 157
Score = 48.9 bits (115), Expect = 4e-06
Identities = 20/45 (44%), Positives = 22/45 (48%)
Frame = +2
Query: 116 CPDGNRCPGYQTCCLSYTGHFGCCPFQLGVCCPGGRTCCRHGQRC 250
C CP QTCC +G +GCCPF VCC CC RC
Sbjct: 283 CDQEVSCPEGQTCCRLQSGKWGCCPFPKAVCCEDHVHCCPERFRC 327
Score = 45.4 bits (106), Expect = 4e-05
Identities = 18/45 (40%), Positives = 20/45 (44%)
Frame = +2
Query: 116 CPDGNRCPGYQTCCLSYTGHFGCCPFQLGVCCPGGRTCCRHGQRC 250
C CP QTCC G + CC VCC G+ CC G C
Sbjct: 441 CDQHASCPVRQTCCPKLGGGWACCQLPHAVCCEDGQHCCPAGYTC 485
Score = 43.9 bits (102), Expect = 1e-04
Identities = 17/49 (34%), Positives = 22/49 (44%)
Frame = +2
Query: 116 CPDGNRCPGYQTCCLSYTGHFGCCPFQLGVCCPGGRTCCRHGQRCVSSG 262
C CP +C L+ G CCPF + C G CC +G C + G
Sbjct: 47 CQSPANCPIGHSCVLTAAGTAACCPFSQAMACGDGHHCCPYGFHCSTDG 95
Score = 33.9 bits (76), Expect = 0.12
Identities = 14/44 (31%), Positives = 19/44 (43%)
Frame = +2
Query: 98 LGNKYICPDGNRCPGYQTCCLSYTGHFGCCPFQLGVCCPGGRTC 229
L ++ C + C CC +G +GCCP G C G C
Sbjct: 372 LRSEISCDEVVSCRPGNICCRLASGEWGCCPSSEGYLCMAGERC 415
>sp|P23785|GRN_RAT Granulins precursor [Contains: Acrogranin; Granulin-1 (Granulin G);
Granulin-2 (Granulin F); Granulin-3 (Granulin B)
(Epithelin-2); Granulin-4 (Granulin A) (Epithelin-1);
Granulin-5 (Granulin C); Granulin-6 (Granulin D);
Granulin-7 (Granulin E)]
Length = 588
Score = 55.1 bits (131), Expect = 5e-08
Identities = 22/55 (40%), Positives = 28/55 (50%)
Frame = +2
Query: 98 LGNKYICPDGNRCPGYQTCCLSYTGHFGCCPFQLGVCCPGGRTCCRHGQRCVSSG 262
L N C D + CP TCC +G +GCCP VCC + CC G +C+ G
Sbjct: 357 LKNDVPCDDFSSCPSNNTCCRLSSGDWGCCPMPEAVCCLDHQHCCPQGFKCMDEG 411
Score = 53.5 bits (127), Expect = 1e-07
Identities = 24/56 (42%), Positives = 30/56 (53%)
Frame = +2
Query: 95 KLGNKYICPDGNRCPGYQTCCLSYTGHFGCCPFQLGVCCPGGRTCCRHGQRCVSSG 262
K+GN C G+ C Q+CC G + CCP+ GVCC GR CC G C + G
Sbjct: 510 KVGNVE-CGAGHFCHDNQSCCKDSQGGWACCPYVKGVCCRDGRHCCPIGFHCSAKG 564
Score = 50.1 bits (118), Expect = 2e-06
Identities = 25/59 (42%), Positives = 30/59 (50%)
Frame = +2
Query: 74 PLNELLIKLGNKYICPDGNRCPGYQTCCLSYTGHFGCCPFQLGVCCPGGRTCCRHGQRC 250
P+NE +K + CPDG TCC TG +GCCPF VCC CC G +C
Sbjct: 275 PVNE--VKCDLEVSCPDG------YTCCRLNTGAWGCCPFTKAVCCEDHIHCCPAGFQC 325
Score = 48.9 bits (115), Expect = 4e-06
Identities = 19/46 (41%), Positives = 21/46 (45%), Gaps = 1/46 (2%)
Frame = +2
Query: 116 CPDGN-RCPGYQTCCLSYTGHFGCCPFQLGVCCPGGRTCCRHGQRC 250
CP CP TCC+ G +GCCP CC CC HG C
Sbjct: 125 CPGSQFECPDSATCCIMIDGSWGCCPMPQASCCEDRVHCCPHGASC 170
Score = 48.9 bits (115), Expect = 4e-06
Identities = 21/54 (38%), Positives = 26/54 (48%), Gaps = 3/54 (5%)
Frame = +2
Query: 113 ICPDGN-RCPGYQTCCLSYTGHFGCCPFQLGVCCPGGRTCCRHGQRC--VSSGC 265
+CPD +CP TCC TG +GCCP +CC CC C + S C
Sbjct: 205 VCPDAKTQCPDDSTCCELPTGKYGCCPMPNAICCSDHLHCCPQDTVCDLIQSKC 258
Score = 48.1 bits (113), Expect = 6e-06
Identities = 19/49 (38%), Positives = 25/49 (51%)
Frame = +2
Query: 116 CPDGNRCPGYQTCCLSYTGHFGCCPFQLGVCCPGGRTCCRHGQRCVSSG 262
C + CP +C L+ +G CCPF GV C G+ CC G C + G
Sbjct: 61 CQIRDHCPDGYSCLLTVSGTSSCCPFSEGVSCDDGQHCCPRGFHCSADG 109
Score = 47.0 bits (110), Expect = 1e-05
Identities = 20/63 (31%), Positives = 27/63 (42%)
Frame = +2
Query: 62 VERKPLNELLIKLGNKYICPDGNRCPGYQTCCLSYTGHFGCCPFQLGVCCPGGRTCCRHG 241
+E+ P+ + + C CP QTCC S G + CC VCC + CC G
Sbjct: 423 LEKMPVRQTTLLQHGDIGCDQHTSCPVGQTCCPSLKGSWACCQLPHAVCCEDRQHCCPAG 482
Query: 242 QRC 250
C
Sbjct: 483 YTC 485
>sp|P28799|GRN_HUMAN Granulins precursor (Proepithelin) (PEPI) [Contains: Acrogranin;
Paragranulin; Granulin-1 (Granulin G); Granulin-2
(Granulin F); Granulin-3 (Granulin B); Granulin-4
(Granulin A); Granulin-5 (Granulin C); Granulin-6
(Granulin D); Granulin-7 (Granulin E)]
Length = 593
Score = 54.3 bits (129), Expect = 8e-08
Identities = 20/49 (40%), Positives = 26/49 (53%)
Frame = +2
Query: 116 CPDGNRCPGYQTCCLSYTGHFGCCPFQLGVCCPGGRTCCRHGQRCVSSG 262
C + + CP TCC +G +GCCP VCC + CC G CV+ G
Sbjct: 366 CDNVSSCPSSDTCCQLTSGEWGCCPIPEAVCCSDHQHCCPQGYTCVAEG 414
Score = 53.9 bits (128), Expect = 1e-07
Identities = 21/49 (42%), Positives = 27/49 (55%)
Frame = +2
Query: 116 CPDGNRCPGYQTCCLSYTGHFGCCPFQLGVCCPGGRTCCRHGQRCVSSG 262
C +G+ C QTCC + CCP++ GVCC R CC G RC + G
Sbjct: 521 CGEGHFCHDNQTCCRDNRQGWACCPYRQGVCCADRRHCCPAGFRCAARG 569
Score = 52.8 bits (125), Expect = 2e-07
Identities = 20/46 (43%), Positives = 23/46 (50%), Gaps = 1/46 (2%)
Frame = +2
Query: 116 CPDGN-RCPGYQTCCLSYTGHFGCCPFQLGVCCPGGRTCCRHGQRC 250
CPD CP + TCC+ G +GCCP CC CC HG C
Sbjct: 126 CPDSQFECPDFSTCCVMVDGSWGCCPMPQASCCEDRVHCCPHGAFC 171
Score = 49.7 bits (117), Expect = 2e-06
Identities = 22/61 (36%), Positives = 29/61 (47%), Gaps = 3/61 (4%)
Frame = +2
Query: 92 IKLGNKYICPDG-NRCPGYQTCCLSYTGHFGCCPFQLGVCCPGGRTCCRHGQRC--VSSG 262
+ L + +CPD +RCP TCC +G +GCCP CC CC C + S
Sbjct: 200 VALSSSVMCPDARSRCPDGSTCCELPSGKYGCCPMPNATCCSDHLHCCPQDTVCDLIQSK 259
Query: 263 C 265
C
Sbjct: 260 C 260
Score = 46.2 bits (108), Expect = 2e-05
Identities = 21/53 (39%), Positives = 25/53 (47%)
Frame = +2
Query: 92 IKLGNKYICPDGNRCPGYQTCCLSYTGHFGCCPFQLGVCCPGGRTCCRHGQRC 250
+K + CPDG TCC +G +GCCPF VCC CC G C
Sbjct: 282 VKCDMEVSCPDG------YTCCRLQSGAWGCCPFTQAVCCEDHIHCCPAGFTC 328
Score = 45.1 bits (105), Expect = 5e-05
Identities = 20/63 (31%), Positives = 25/63 (39%)
Frame = +2
Query: 62 VERKPLNELLIKLGNKYICPDGNRCPGYQTCCLSYTGHFGCCPFQLGVCCPGGRTCCRHG 241
+E+ P + C CP QTCC S G + CC VCC + CC G
Sbjct: 426 LEKMPARRASLSHPRDIGCDQHTSCPVGQTCCPSLGGSWACCQLPHAVCCEDRQHCCPAG 485
Query: 242 QRC 250
C
Sbjct: 486 YTC 488
Score = 40.4 bits (93), Expect = 0.001
Identities = 16/49 (32%), Positives = 20/49 (40%)
Frame = +2
Query: 116 CPDGNRCPGYQTCCLSYTGHFGCCPFQLGVCCPGGRTCCRHGQRCVSSG 262
C C +C + +G CCPF V C G CC G C + G
Sbjct: 61 CQVDAHCSAGHSCIFTVSGTSSCCPFPEAVACGDGHHCCPRGFHCSADG 109
>sp|P80059|PMD1_LOCMI Pars intercerebralis major peptide D1 (PMP-D1)
Length = 54
Score = 53.5 bits (127), Expect = 1e-07
Identities = 20/39 (51%), Positives = 24/39 (61%)
Frame = +2
Query: 134 CPGYQTCCLSYTGHFGCCPFQLGVCCPGGRTCCRHGQRC 250
CPG +TCC + G GCCP++ GVCC G CC G C
Sbjct: 7 CPGTETCCTTPQGEEGCCPYKEGVCCLDGIHCCPSGTVC 45
>sp|P80930|ENA1_HORSE Antimicrobial peptide eNAP-1
Length = 46
Score = 49.7 bits (117), Expect = 2e-06
Identities = 19/42 (45%), Positives = 23/42 (54%)
Frame = +2
Query: 116 CPDGNRCPGYQTCCLSYTGHFGCCPFQLGVCCPGGRTCCRHG 241
C +G+ C QTCC + G CCP+ GVCC R CC G
Sbjct: 4 CGEGHFCHDXQTCCRASQGGXACCPYSQGVCCADQRHCCPVG 45
>sp|P43297|RD21A_ARATH Cysteine proteinase RD21a precursor (RD21)
Length = 462
Score = 43.9 bits (102), Expect = 1e-04
Identities = 18/47 (38%), Positives = 22/47 (46%), Gaps = 4/47 (8%)
Frame = +2
Query: 110 YICPDGNRCPGYQTCCLSYTGHF----GCCPFQLGVCCPGGRTCCRH 238
Y CP+ N C CCL G + GCCP + CC +CC H
Sbjct: 379 YTCPESNTC-----CCLFEYGKYCFAWGCCPLEAATCCDDNYSCCPH 420
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 41,735,117
Number of Sequences: 369166
Number of extensions: 874655
Number of successful extensions: 2622
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 2423
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 2593
length of database: 68,354,980
effective HSP length: 95
effective length of database: 50,805,155
effective search space used: 1676570115
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)