Planaria EST Database

DrC_00592

BLASTX 2.2.13 [Nov-27-2005]

Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= DrC_00592
         (876 letters)

Database: Non-redundant SwissProt sequences 
           184,735 sequences; 68,354,980 total letters



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

sp|Q16563|SYPL_HUMAN  Synaptophysin-like protein (Pantophysin)     79   2e-14
sp|P07825|SYPH_RAT  Synaptophysin (Major synaptic vesicle pr...    77   8e-14
sp|Q62277|SYPH_MOUSE  Synaptophysin (Major synaptic vesicle ...    77   8e-14
sp|P08247|SYPH_HUMAN  Synaptophysin (Major synaptic vesicle ...    76   1e-13
sp|P20488|SYPH_BOVIN  Synaptophysin (Major synaptic vesicle ...    76   1e-13
sp|O09117|SYPL_MOUSE  Synaptophysin-like protein (Pantophysin)     74   7e-13
sp|Q8BGN8|SYNPR_MOUSE  Synaptoporin                                70   1e-11
sp|P22831|SYNPR_RAT  Synaptoporin                                  69   2e-11
sp|Q8TBG9|SYNPR_HUMAN  Synaptoporin                                68   4e-11
sp|Q5VXT5|SYPL2_HUMAN  Synaptophysin-like protein 2                62   2e-09

>sp|Q16563|SYPL_HUMAN Synaptophysin-like protein (Pantophysin)
          Length = 259

 Score = 79.0 bits (193), Expect = 2e-14
 Identities = 64/234 (27%), Positives = 87/234 (37%), Gaps = 12/234 (5%)
 Frame = +1

Query: 52  NLEVFKEPKGXXXXXXXXXXXXXXXXXXXXGGKVSLFFNCTDLPAITINVDVY----YPF 219
           NL   KEP G                     G+  +  NC   PA+T N  V     YPF
Sbjct: 25  NLNPLKEPLGFIKVLEWIASIFAFATCGGFKGQTEIQVNCP--PAVTENKTVTATFGYPF 82

Query: 220 NLVNQ--------NITVWNATNIAAKINYESSAQFSVFISSVSLIYCLCALAVYILLNDF 375
            L           NI   N  +     +Y SSAQF V  +    +YC+ AL +Y+     
Sbjct: 83  RLNEASFQPPPGVNICDVNWKDYVLIGDYSSSAQFYVTFAVFVFLYCIAALLLYVGYTSL 142

Query: 376 LYQDPKIRKADFVIEAVLTFLWFVVGIAWSDVSVKLKSDISTSLCGQLTPSLKSHSNVTC 555
                K+   DFV+  V TFLW V   AW+     +K     ++  +L P  K    V C
Sbjct: 143 YLDSRKLPMIDFVVTLVATFLWLVSTSAWAKALTDIKIATGHNIIDELPPCKK--KAVLC 200

Query: 556 SVAKDIPFGSAYIGIIASFTTFCLMLSGLWFLWKETAWFKSPPQSNPYVDNESP 717
                   GS  + +I  F    L     WF++KET+       S P+     P
Sbjct: 201 YFGSVTSMGSLNVSVIFGFLNMILWGGNAWFVYKETSLHSPSNTSAPHSQGGIP 254

>sp|P07825|SYPH_RAT Synaptophysin (Major synaptic vesicle protein p38)
          Length = 307

 Score = 76.6 bits (187), Expect = 8e-14
 Identities = 61/239 (25%), Positives = 96/239 (40%), Gaps = 9/239 (3%)
 Frame = +1

Query: 61  VFKEPKGXXXXXXXXXXXXXXXXXXXXGGKVSLFFNCTDLP--AITINVDVYYPFNLVN- 231
           V KEP G                     G++ L   C +    A+ I V+  YPF L   
Sbjct: 15  VVKEPLGFVKVLQWVFAIFAFATCGSYTGELRLSVECANKTESALNIEVEFEYPFRLHQV 74

Query: 232 ----QNITVWNATNIAAKINYESSAQFSVFISSVSLIYCLCALAVYILLNDFLYQDPKIR 399
                +      T I    +Y SSA+F V ++  + +Y + ALA YI L +   ++ K  
Sbjct: 75  YFDAPSCVKGGTTKIFLVGDYSSSAEFFVTVAVFAFLYSMGALATYIFLQNKYRENNKGP 134

Query: 400 KADFVIEAVLTFLWFVVGIAWSD--VSVKLKSDISTSLCGQLTPSLKSHSNVTCSVAKDI 573
             DF+  AV  F+W V   AW+     VK+ +D    +  +  P  +   N TC   +D 
Sbjct: 135 MMDFLATAVFAFMWLVSSSAWAKGLSDVKMATDPENII--KEMPMCRQTGN-TCKELRDP 191

Query: 574 PFGSAYIGIIASFTTFCLMLSGLWFLWKETAWFKSPPQSNPYVDNESPRGDESQNDRTY 750
                   ++  F    L +  LWF++KET W     ++ P    + P   ++  D  Y
Sbjct: 192 VTSGLNTSVVFGFLNLVLWVGNLWFVFKETGWAAPFMRAPPGAPEKQPAPGDAYGDAGY 250

>sp|Q62277|SYPH_MOUSE Synaptophysin (Major synaptic vesicle protein p38) (BM89 antigen)
          Length = 314

 Score = 76.6 bits (187), Expect = 8e-14
 Identities = 61/239 (25%), Positives = 96/239 (40%), Gaps = 9/239 (3%)
 Frame = +1

Query: 61  VFKEPKGXXXXXXXXXXXXXXXXXXXXGGKVSLFFNCTDLP--AITINVDVYYPFNLVN- 231
           V KEP G                     G++ L   C +    A+ I V+  YPF L   
Sbjct: 21  VVKEPLGFVKVLQWVFAIFAFATCGSYTGELRLSVECANKTESALNIEVEFEYPFRLHQV 80

Query: 232 ----QNITVWNATNIAAKINYESSAQFSVFISSVSLIYCLCALAVYILLNDFLYQDPKIR 399
                +      T I    +Y SSA+F V ++  + +Y + ALA YI L +   ++ K  
Sbjct: 81  YFDAPSCVKGGTTKIFLVGDYSSSAEFFVTVAVFAFLYSMGALATYIFLQNKYRENNKGP 140

Query: 400 KADFVIEAVLTFLWFVVGIAWSD--VSVKLKSDISTSLCGQLTPSLKSHSNVTCSVAKDI 573
             DF+  AV  F+W V   AW+     VK+ +D    +  +  P  +   N TC   +D 
Sbjct: 141 MMDFLATAVFAFMWLVSSSAWAKGLSDVKMATDPENII--KEMPMCRQTGN-TCKELRDP 197

Query: 574 PFGSAYIGIIASFTTFCLMLSGLWFLWKETAWFKSPPQSNPYVDNESPRGDESQNDRTY 750
                   ++  F    L +  LWF++KET W     ++ P    + P   ++  D  Y
Sbjct: 198 VTSGLNTSVVFGFLNLVLWVGNLWFVFKETGWAAPFMRAPPGAPEKQPAPGDAYGDAGY 256

>sp|P08247|SYPH_HUMAN Synaptophysin (Major synaptic vesicle protein p38)
          Length = 313

 Score = 75.9 bits (185), Expect = 1e-13
 Identities = 59/238 (24%), Positives = 96/238 (40%), Gaps = 8/238 (3%)
 Frame = +1

Query: 61  VFKEPKGXXXXXXXXXXXXXXXXXXXXGGKVSLFFNCTDLPA--ITINVDVYYPFNLVNQ 234
           V KEP G                     G++ L  +C +     ++I V+  YPF L   
Sbjct: 21  VVKEPLGFVKVLQWVFAIFAFATCGSYSGELQLSVDCANKTESDLSIEVEFEYPFRLHQV 80

Query: 235 NITVWNATNIAAKI----NYESSAQFSVFISSVSLIYCLCALAVYILLNDFLYQDPKIRK 402
                       K+    +Y SSA+F V ++  + +Y + ALA YI L +   ++ K   
Sbjct: 81  YFDAPTCRGGTTKVFLVGDYSSSAEFFVTVAVFAFLYSMGALATYIFLQNKYRENNKGPM 140

Query: 403 ADFVIEAVLTFLWFVVGIAWSD--VSVKLKSDISTSLCGQLTPSLKSHSNVTCSVAKDIP 576
            DF+  AV  F+W V   AW+     VK+ +D    +  +  P  +   N TC   +D  
Sbjct: 141 LDFLATAVFAFMWLVSSSAWAKGLSDVKMATDPENII--KEMPVCRQTGN-TCKELRDPV 197

Query: 577 FGSAYIGIIASFTTFCLMLSGLWFLWKETAWFKSPPQSNPYVDNESPRGDESQNDRTY 750
                  ++  F    L +  LWF++KET W     ++ P    + P   ++  D  Y
Sbjct: 198 TSGLNTSVVFGFLNLVLWVGNLWFVFKETGWAAPFLRAPPGAPEKQPAPGDAYGDAGY 255

>sp|P20488|SYPH_BOVIN Synaptophysin (Major synaptic vesicle protein p38)
          Length = 313

 Score = 75.9 bits (185), Expect = 1e-13
 Identities = 58/220 (26%), Positives = 89/220 (40%), Gaps = 12/220 (5%)
 Frame = +1

Query: 61  VFKEPKGXXXXXXXXXXXXXXXXXXXXGGKVSLFFNCTDLPAITINVDVY--YPFNLVNQ 234
           V KEP G                     G++ L  +C +     +N++V   YPF L   
Sbjct: 21  VVKEPLGFVKVLQWVFAIFAFATCGSYSGELQLSVDCANKTKSDLNIEVEFEYPFRLHEV 80

Query: 235 NITVWNATNIAAKI----NYESSAQFSVFISSVSLIYCLCALAVYILLNDFLYQDPKIRK 402
                       KI    NY SSA+F V ++  + +Y + ALA YI L +   ++ K   
Sbjct: 81  YFEAPTCQGDPKKIFLVGNYSSSAEFFVTVAVFAFLYSMGALATYIFLQNKYRENNKGPM 140

Query: 403 ADFVIEAVLTFLWFVVGIAWSD--VSVKLKSDISTSLCGQLTPSLKSHSNVTCSVAKDIP 576
            DF+  AV  F+W V   AW+     VK+ +D    + G     +      TC   +D  
Sbjct: 141 LDFLATAVFAFMWLVSSSAWAKGLSDVKMATDPENIIKGM---HVCHQPGNTCKELRDPV 197

Query: 577 FGSAYIGIIASFTTFCLMLSGLWFLWKETAW----FKSPP 684
                  ++  F    L +  LWF++KET W     ++PP
Sbjct: 198 TSGLNTSVVFGFLNLVLWVGNLWFVFKETGWAAPFLRAPP 237

>sp|O09117|SYPL_MOUSE Synaptophysin-like protein (Pantophysin)
          Length = 261

 Score = 73.6 bits (179), Expect = 7e-13
 Identities = 60/222 (27%), Positives = 88/222 (39%), Gaps = 17/222 (7%)
 Frame = +1

Query: 52  NLEVFKEPKGXXXXXXXXXXXXXXXXXXXXGGKVSLFFNCTDLPAI---TINVDVYYPFN 222
           NL   KEP G                     GK  +  NC  +      T+     YPF 
Sbjct: 25  NLNPLKEPLGFIKILEWFASIFAFATCGGFKGKTEIQVNCPKVGVNKNQTVTATFGYPFR 84

Query: 223 LVNQ-------NITV----WNATNIAAKINYESSAQFSVFISSVSLIYCLCALAVYILLN 369
           L NQ       N++V    W    +    +Y SSAQF V  +    +YC+ AL +Y+   
Sbjct: 85  L-NQASFHTPPNVSVCDVNWEKHVLIG--DYSSSAQFYVTFAVFVFLYCIAALLLYVGYT 141

Query: 370 DFLYQDPKIRKADFVIEAVLTFLWFVVGIAWSDVSVKLKSDISTSLCGQLTPSLK---SH 540
           +      K+   DF++  V TFLW V   AW+    K  +DI  +   ++   L+     
Sbjct: 142 NLYRDSRKLPMIDFIVTLVATFLWLVSSSAWA----KALTDIKVATGHRIVEELEICNPE 197

Query: 541 SNVTCSVAKDIPFGSAYIGIIASFTTFCLMLSGLWFLWKETA 666
           S V+C        GS  + +I  F    L     WF++KET+
Sbjct: 198 SGVSCYFVSVTSMGSLNVSVIFGFLNMILWGGNAWFVYKETS 239

>sp|Q8BGN8|SYNPR_MOUSE Synaptoporin
          Length = 265

 Score = 69.7 bits (169), Expect = 1e-11
 Identities = 57/215 (26%), Positives = 92/215 (42%), Gaps = 13/215 (6%)
 Frame = +1

Query: 145 GKVSLFFNCTDLPAITINVDVY--YPFNLVNQNITVWNAT-------NIAAKINYESSAQ 297
           G + L  +C +     +++D+   YPF L  Q +T    T        +A   +  SSA+
Sbjct: 23  GGLRLSVDCVNKTESNLSIDIAFAYPFRL--QQVTFEVPTCEGKEQQKLALVGDSSSSAE 80

Query: 298 FSVFISSVSLIYCLCALAVYILLNDFLYQDPKIRKADFVIEAVLTFLWFVVGIAWSD--V 471
           F V ++  + +Y L A  VYI   +   ++ +    DF++  V +FLW V   AW+    
Sbjct: 81  FFVTVAVFAFLYSLAATVVYIFFQNKYRENNRGPLIDFIVTVVFSFLWLVGSSAWAKGLS 140

Query: 472 SVKLKSDISTSLCGQLTPSLKSHSNVTCSVAKDIPFGSAYIGIIASFTTFCLMLSGLWFL 651
            VK+ +D    L   L  + K  SN  C         S    ++  F  F L    +WF+
Sbjct: 141 DVKVATDPKEVLL--LMSACKQPSN-KCMAVHSPVMSSLNTSVVFGFLNFILWAGNIWFV 197

Query: 652 WKETAWFKSPPQ--SNPYVDNESPRGDESQNDRTY 750
           +KET W  S  +  S+P   + S       N  +Y
Sbjct: 198 FKETGWHSSGQRYLSDPMEKHSSSYNQGRYNQESY 232

>sp|P22831|SYNPR_RAT Synaptoporin
          Length = 265

 Score = 68.6 bits (166), Expect = 2e-11
 Identities = 55/213 (25%), Positives = 89/213 (41%), Gaps = 11/213 (5%)
 Frame = +1

Query: 145 GKVSLFFNCTDLPAITINVDVY--YPFNLVNQNITVWNATN-----IAAKINYESSAQFS 303
           G + L  +C +     +++D+   YPF L      V          +A   +  SSA+F 
Sbjct: 23  GGLRLSVDCVNKTESNLSIDIAFAYPFRLHQVTFEVPTCEGKERQKLALVGDSSSSAEFF 82

Query: 304 VFISSVSLIYCLCALAVYILLNDFLYQDPKIRKADFVIEAVLTFLWFVVGIAWSD--VSV 477
           V ++  + +Y L A  VYI   +   ++ +    DF++  V +FLW V   AW+     V
Sbjct: 83  VTVAVFAFLYSLAATVVYIFFQNKYRENNRGPLIDFIVTVVFSFLWLVGSSAWAKGLSDV 142

Query: 478 KLKSDISTSLCGQLTPSLKSHSNVTCSVAKDIPFGSAYIGIIASFTTFCLMLSGLWFLWK 657
           K+ +D    L   L  + K  SN  C         S    ++  F  F L    +WF++K
Sbjct: 143 KVATDPKEVLL--LMSACKQPSN-KCMAVHSPVMSSLNTSVVFGFLNFILWAGNIWFVFK 199

Query: 658 ETAWFKSPPQ--SNPYVDNESPRGDESQNDRTY 750
           ET W  S  +  S+P   + S       N  +Y
Sbjct: 200 ETGWHSSGQRYLSDPMEKHSSSYNQGGYNQDSY 232

>sp|Q8TBG9|SYNPR_HUMAN Synaptoporin
          Length = 265

 Score = 67.8 bits (164), Expect = 4e-11
 Identities = 55/213 (25%), Positives = 89/213 (41%), Gaps = 11/213 (5%)
 Frame = +1

Query: 145 GKVSLFFNCTDLPAITINVDVY--YPFNLVNQNITVWNATN-----IAAKINYESSAQFS 303
           G + L  +C +     +++D+   YPF L      V          +A   +  SSA+F 
Sbjct: 23  GGLRLSVDCVNKTESNLSIDIAFAYPFRLHQVTFEVPTCEGKERQKLALIGDSSSSAEFF 82

Query: 304 VFISSVSLIYCLCALAVYILLNDFLYQDPKIRKADFVIEAVLTFLWFVVGIAWSD--VSV 477
           V ++  + +Y L A  VYI   +   ++ +    DF++  V +FLW V   AW+     V
Sbjct: 83  VTVAVFAFLYSLAATVVYIFFQNKYRENNRGPLIDFIVTVVFSFLWLVGSSAWAKGLSDV 142

Query: 478 KLKSDISTSLCGQLTPSLKSHSNVTCSVAKDIPFGSAYIGIIASFTTFCLMLSGLWFLWK 657
           K+ +D    L   L  + K  SN  C         S    ++  F  F L    +WF++K
Sbjct: 143 KVATDPKEVLL--LMSACKQPSN-KCMAIHSPVMSSLNTSVVFGFLNFILWAGNIWFVFK 199

Query: 658 ETAWFKSPPQ--SNPYVDNESPRGDESQNDRTY 750
           ET W  S  +  S+P   + S       N  +Y
Sbjct: 200 ETGWHSSGQRYLSDPMEKHSSSYNQGGYNQDSY 232

>sp|Q5VXT5|SYPL2_HUMAN Synaptophysin-like protein 2
          Length = 272

 Score = 62.4 bits (150), Expect = 2e-09
 Identities = 36/156 (23%), Positives = 62/156 (39%), Gaps = 2/156 (1%)
 Frame = +1

Query: 277 NYESSAQFSVFISSVSLIYCLCALAVYILLNDFLYQDPKIRKADFVIEAVLTFLWFVVGI 456
           ++ + A+F V +   S  Y + AL +Y+  ++   ++ +    DF +    TF W V   
Sbjct: 110 DFSAPAEFFVTLGIFSFFYTMAALVIYLRFHNLYTENKRFPLVDFCVTVSFTFFWLVAAA 169

Query: 457 AWSDVSVKLKSDISTSLCGQLTPSLK--SHSNVTCSVAKDIPFGSAYIGIIASFTTFCLM 630
           AW      +K     S    LT ++         CS       G A I ++  F  F L 
Sbjct: 170 AWGKGLTDVKGATRPS---SLTAAMSVCHGEEAVCSAGATPSMGLANISVLFGFINFFLW 226

Query: 631 LSGLWFLWKETAWFKSPPQSNPYVDNESPRGDESQN 738
               WF++KET W       +   D +  +G   ++
Sbjct: 227 AGNCWFVFKETPWHGQGQGQDQDQDQDQGQGPSQES 262

  Database: Non-redundant SwissProt sequences
    Posted date:  Dec 6, 2005  7:40 AM
  Number of letters in database: 68,354,980
  Number of sequences in database:  184,735
  
  Database: swissprot.01
    Posted date:  Dec 6, 2005  8:18 AM
  Number of letters in database: 66,202,850
  Number of sequences in database:  184,431
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 94,731,126
Number of Sequences: 369166
Number of extensions: 1797069
Number of successful extensions: 4952
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 4701
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4933
length of database: 68,354,980
effective HSP length: 110
effective length of database: 48,034,130
effective search space used: 8694177530
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)

Cluster detail

DrC_00592

  1. Dr_sW_015_H11
  2. Dr_sW_001_L19