Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= DrC_00586 (553 letters) Database: Non-redundant SwissProt sequences 184,735 sequences; 68,354,980 total letters Score E Sequences producing significant alignments: (bits) Value sp|P01267|THYG_BOVIN Thyroglobulin precursor 62 7e-10 sp|P31226|SAX_RANCA Saxiphilin precursor (SAX) 59 6e-09 sp|P81439|EQST_ACTEQ Equistatin 59 6e-09 sp|P01266|THYG_HUMAN Thyroglobulin precursor 58 1e-08 sp|P06882|THYG_RAT Thyroglobulin precursor 58 2e-08 sp|O08710|THYG_MOUSE Thyroglobulin precursor 57 3e-08 sp|Q8BKV0|TICN3_MOUSE Testican-3 precursor (SPARC/osteonect... 50 4e-06 sp|Q9BQ16|TICN3_HUMAN Testican-3 precursor (SPARC/osteonect... 49 6e-06 sp|Q5RD69|TICN3_PONPY Testican-3 precursor (SPARC/osteonect... 49 6e-06 sp|Q62288|TICN1_MOUSE Testican-1 precursor (SPOCK protein) 49 1e-05
>sp|P01267|THYG_BOVIN Thyroglobulin precursor Length = 2769 Score = 62.4 bits (150), Expect = 7e-10 Identities = 33/104 (31%), Positives = 48/104 (46%), Gaps = 8/104 (7%) Frame = +3 Query: 189 LTLPNCDMEGNYARNQCTGSVCYCVDKYGFQIDKYSFNIGLSANSNCNCARDEVNFKSKK 368 L +P C EG+Y QC C+CVD G ++ G C ++ + + Sbjct: 614 LFVPACTAEGSYEEVQCFAGDCWCVDAQGRELAGSRVRGG---RPRCPTECEKQRARMQS 670 Query: 369 ILG--------LTFSCANNGNYNPVQCVGSSCFCADEIGKPIPG 476 +LG +C + GN+ PVQC S C+C D G+PIPG Sbjct: 671 LLGSQPAGSSLFVPACTSKGNFLPVQCFNSECYCVDTEGQPIPG 714
Score = 40.4 bits (93), Expect = 0.003 Identities = 29/102 (28%), Positives = 47/102 (46%), Gaps = 3/102 (2%) Frame = +3 Query: 189 LTLPNCDMEGNYARNQCTGSVCYCVDKYGFQIDKYSFNIGLSANSNCNCARDEVNFKSKK 368 L +P C G +AR Q + + +CVD + N S C + V + + Sbjct: 1103 LFIPTCLETGEFARLQASEAGTWCVDPASGEGVPPGTNSSAQCPSLCEVLQSGVPSR-RT 1161 Query: 369 ILGLTFSC-ANNGNYNPVQC--VGSSCFCADEIGKPIPGGKV 485 G + +C A +G ++PVQC SC+C G+ +PG +V Sbjct: 1162 SPGYSPACRAEDGGFSPVQCDPAQGSCWCVLGSGEEVPGTRV 1203
Score = 39.7 bits (91), Expect = 0.005 Identities = 37/141 (26%), Positives = 52/141 (36%), Gaps = 14/141 (9%) Frame = +3 Query: 51 NVSGRCYNSKKCRGKFVCLFNECQKNPLNTTCLEQYEKVKSSKLLGLTLPNCDMEGNYAR 230 + GR + RG EC+K L + SS L +P C +GN+ Sbjct: 639 DAQGRELAGSRVRGGRPRCPTECEKQRARMQSLLGSQPAGSS----LFVPACTSKGNFLP 694 Query: 231 NQCTGSVCYCVDKYGFQIDKYSFNIG--LSANSNCNCARDEVNFKSKKILGLTFS----- 389 QC S CYCVD G I +G S C + + + L S Sbjct: 695 VQCFNSECYCVDTEGQPIPGTRSALGEPKKCPSPCQLQAERAFLGTVRTLVSNPSTLPAL 754 Query: 390 -------CANNGNYNPVQCVG 431 C+ +G ++PVQC G Sbjct: 755 SSIYIPQCSASGQWSPVQCDG 775
Score = 39.3 bits (90), Expect = 0.006 Identities = 28/103 (27%), Positives = 48/103 (46%), Gaps = 9/103 (8%) Frame = +3 Query: 195 LPNCDMEGNYARNQC--TGSVCYCVDKYGFQIDKYSFNIGLSAN--SNCNCARDEV---N 353 +P C +G++ QC G+ C+CVD G ++ S G A S C + ++ + Sbjct: 49 VPQCAEDGSFQTVQCGKDGASCWCVDADGREVPG-SRQPGRPAACLSFCQLQKQQILLSS 107 Query: 354 FKSKKILGLTFSCANNGNYNPVQC--VGSSCFCADEIGKPIPG 476 + + C ++G+Y+PVQC C+C D G + G Sbjct: 108 YINSTATSYLPQCQDSGDYSPVQCDLRRRQCWCVDAEGMEVYG 150
Score = 36.2 bits (82), Expect = 0.055 Identities = 14/33 (42%), Positives = 22/33 (66%), Gaps = 2/33 (6%) Frame = +3 Query: 390 CANNGNYNPVQCV--GSSCFCADEIGKPIPGGK 482 CA +G++ VQC G+SC+C D G+ +PG + Sbjct: 52 CAEDGSFQTVQCGKDGASCWCVDADGREVPGSR 84
Score = 35.0 bits (79), Expect = 0.12 Identities = 12/33 (36%), Positives = 18/33 (54%) Frame = +3 Query: 387 SCANNGNYNPVQCVGSSCFCADEIGKPIPGGKV 485 +C G+Y VQC C+C D G+ + G +V Sbjct: 618 ACTAEGSYEEVQCFAGDCWCVDAQGRELAGSRV 650
Score = 32.3 bits (72), Expect = 0.79 Identities = 14/31 (45%), Positives = 17/31 (54%), Gaps = 1/31 (3%) Frame = +3 Query: 387 SCANNGNYNPVQCV-GSSCFCADEIGKPIPG 476 SC +G Y QC G C+C D G+ IPG Sbjct: 318 SCHPDGEYQAAQCQQGGPCWCVDSRGQEIPG 348
>sp|P31226|SAX_RANCA Saxiphilin precursor (SAX) Length = 844 Score = 59.3 bits (142), Expect = 6e-09 Identities = 41/128 (32%), Positives = 60/128 (46%), Gaps = 15/128 (11%) Frame = +3 Query: 144 CLEQYEKVKSSKLLGLTLPNCDMEGNYARNQCTGSV--CYCVDKYGFQIDKYSFNIGLSA 317 CL++ ++ + K++G +P CD +GNY QC GS C+CV+ G +K S Sbjct: 110 CLKERQQALAKKMIGHYIPQCDEKGNYQPQQCHGSTGHCWCVNAMG---EKISGTNTPPG 166 Query: 318 NSNCNCARDEVNFKSK----------KILG-LTFSCANNGNYNPVQCVGSS--CFCADEI 458 + C R E+ K K+LG C GNY P Q GS+ +C + I Sbjct: 167 QTRATCERHELPKCLKERQVALGGDEKVLGRFVPQCDEKGNYEPQQFHGSTGYSWCVNAI 226 Query: 459 GKPIPGGK 482 G+ I G K Sbjct: 227 GEEIAGTK 234
>sp|P81439|EQST_ACTEQ Equistatin Length = 199 Score = 59.3 bits (142), Expect = 6e-09 Identities = 36/103 (34%), Positives = 52/103 (50%), Gaps = 7/103 (6%) Frame = +3 Query: 198 PNCDMEGNYARNQCTGS--VCYCVDKYGFQIDKYSFNIGLSAN---SNCNCARDEVNFKS 362 P+C +G++ QC S CYCVDK G +++ S S C AR + + S Sbjct: 90 PSCKADGSFDEVQCCASNGECYCVDKKGKELEGTRQKGRPSCERHLSPCEEARLQAHSNS 149 Query: 363 KKILGLTFSCANNGNYNPVQCVGSS--CFCADEIGKPIPGGKV 485 ++ C +G+YNPVQC S+ C+C DE G +PG V Sbjct: 150 LRVGMFVPQCLEDGSYNPVQCWPSTGYCWCVDEGGVKVPGSDV 192
Score = 53.9 bits (128), Expect = 3e-07 Identities = 33/123 (26%), Positives = 58/123 (47%), Gaps = 14/123 (11%) Frame = +3 Query: 150 EQYEKVKSSKLLGLTLPNCDMEGNYARNQCTGSV--CYCVDKYGFQIDKYSFNIGLSANS 323 +Q + +S L+G +P C G + QC GS C+CVD+ G +I +G Sbjct: 6 QQLQASANSGLIGAYVPQCKETGEFEEKQCWGSTGYCWCVDEDGKEI------LGTKIRG 59 Query: 324 NCNCARDEVNFKSKKILGLTF----------SCANNGNYNPVQCVGSS--CFCADEIGKP 467 + +C+R + +++ SC +G+++ VQC S+ C+C D+ GK Sbjct: 60 SPDCSRRKAALTLCQMMQAIIVNVPGWCGPPSCKADGSFDEVQCCASNGECYCVDKKGKE 119 Query: 468 IPG 476 + G Sbjct: 120 LEG 122
Score = 30.4 bits (67), Expect = 3.0 Identities = 17/50 (34%), Positives = 28/50 (56%), Gaps = 3/50 (6%) Frame = +3 Query: 144 CLEQYEKVKSSKL-LGLTLPNCDMEGNYARNQCTGSV--CYCVDKYGFQI 284 C E + S+ L +G+ +P C +G+Y QC S C+CVD+ G ++ Sbjct: 138 CEEARLQAHSNSLRVGMFVPQCLEDGSYNPVQCWPSTGYCWCVDEGGVKV 187
>sp|P01266|THYG_HUMAN Thyroglobulin precursor Length = 2768 Score = 58.2 bits (139), Expect = 1e-08 Identities = 31/102 (30%), Positives = 49/102 (48%), Gaps = 6/102 (5%) Frame = +3 Query: 189 LTLPNCDMEGNYARNQCTGSVCYCVDKYGFQIDKYSFNIGLSANSNCNCARDEVNFKS-- 362 L +P+C EG+Y QC C+CV+ +G ++ G +C + +S Sbjct: 615 LFVPSCTTEGSYEDVQCFSGECWCVNSWGKELPGSRVRGG-QPRCPTDCEKQRARMQSLM 673 Query: 363 -KKILGLTF---SCANNGNYNPVQCVGSSCFCADEIGKPIPG 476 + G T +C + G++ PVQC S C+C D G+ IPG Sbjct: 674 GSQPAGSTLFVPACTSEGHFLPVQCFNSECYCVDAEGQAIPG 715
Score = 47.4 bits (111), Expect = 2e-05 Identities = 31/102 (30%), Positives = 49/102 (48%), Gaps = 3/102 (2%) Frame = +3 Query: 189 LTLPNCDMEGNYARNQCTGSVCYCVDKYGFQIDKYSFNIGLSANSNCNCARDEVNFKSKK 368 L +P C G YAR Q +G+ +CVD + + + S CN + V + Sbjct: 1103 LFVPACLETGEYARLQASGAGTWCVDPASGEELRPGSSSSAQCPSLCNVLKSGV-LSRRV 1161 Query: 369 ILGLTFSC-ANNGNYNPVQC--VGSSCFCADEIGKPIPGGKV 485 G +C A +G ++PVQC SC+C + G+ +PG +V Sbjct: 1162 SPGYVPACRAEDGGFSPVQCDQAQGSCWCVMDSGEEVPGTRV 1203
Score = 39.7 bits (91), Expect = 0.005 Identities = 14/33 (42%), Positives = 19/33 (57%) Frame = +3 Query: 387 SCANNGNYNPVQCVGSSCFCADEIGKPIPGGKV 485 SC G+Y VQC C+C + GK +PG +V Sbjct: 619 SCTTEGSYEDVQCFSGECWCVNSWGKELPGSRV 651
Score = 34.3 bits (77), Expect = 0.21 Identities = 24/102 (23%), Positives = 43/102 (42%), Gaps = 8/102 (7%) Frame = +3 Query: 195 LPNCDMEGNYARNQCT--GSVCYCVDKYGFQI-DKYSFNIGLSANSNCNCARDEV---NF 356 +P C +G++ QC G C+CV G ++ ++ S C + ++ + Sbjct: 49 VPQCAEDGSFQTVQCQNDGRSCWCVGANGSEVLGSRQPGRPVACLSFCQLQKQQILLSGY 108 Query: 357 KSKKILGLTFSCANNGNYNPVQC--VGSSCFCADEIGKPIPG 476 + C ++G+Y PVQC C+C D G + G Sbjct: 109 INSTDTSYLPQCQDSGDYAPVQCDVQQVQCWCVDAEGMEVYG 150
Score = 31.6 bits (70), Expect = 1.4 Identities = 14/31 (45%), Positives = 17/31 (54%), Gaps = 1/31 (3%) Frame = +3 Query: 387 SCANNGNYNPVQC-VGSSCFCADEIGKPIPG 476 SC NG+Y VQC C+C D GK + G Sbjct: 318 SCRRNGDYQAVQCQTEGPCWCVDAQGKEMHG 348
Score = 30.0 bits (66), Expect = 3.9 Identities = 27/106 (25%), Positives = 40/106 (37%), Gaps = 17/106 (16%) Frame = +3 Query: 186 GLTLPNCDMEGNYARNQCTGSV--CYCVDKYG-----------FQIDKYSFNIGLSAN-- 320 G +P CD G++ QC C+CVD+ G QI + S Sbjct: 1025 GPYMPQCDAFGSWEPVQCHAGTGHCWCVDEKGGFIPGSLTARSLQIPQCPTTCEKSRTSG 1084 Query: 321 --SNCNCARDEVNFKSKKILGLTFSCANNGNYNPVQCVGSSCFCAD 452 S+ AR + N K + +C G Y +Q G+ +C D Sbjct: 1085 LLSSWKQARSQENPSPKDL--FVPACLETGEYARLQASGAGTWCVD 1128
Score = 29.6 bits (65), Expect = 5.1 Identities = 14/31 (45%), Positives = 18/31 (58%), Gaps = 2/31 (6%) Frame = +3 Query: 390 CANNGNYNPVQCVGSS--CFCADEIGKPIPG 476 C G++ PVQC + C+C DE G IPG Sbjct: 1031 CDAFGSWEPVQCHAGTGHCWCVDEKGGFIPG 1061
>sp|P06882|THYG_RAT Thyroglobulin precursor Length = 2768 Score = 57.8 bits (138), Expect = 2e-08 Identities = 31/99 (31%), Positives = 50/99 (50%), Gaps = 5/99 (5%) Frame = +3 Query: 195 LPNCDMEGNYARNQCTGSVCYCVDKYGFQIDKYSFNIGLS-ANSNCNCARDEV-NFKSKK 368 +P+C EG+Y QC C+CV+ G +++ + G + C R ++ N + Sbjct: 617 VPSCTAEGSYEDIQCYAGECWCVNSQGKEVEGSRVSGGHPRCPTKCEKQRAQMQNLAGAQ 676 Query: 369 ILGLTF---SCANNGNYNPVQCVGSSCFCADEIGKPIPG 476 G +F +C + G + PVQC S C+C D G+ IPG Sbjct: 677 PAGSSFFVPTCTSEGYFLPVQCFNSECYCVDAEGQVIPG 715
Score = 48.9 bits (115), Expect = 8e-06 Identities = 34/104 (32%), Positives = 50/104 (48%), Gaps = 4/104 (3%) Frame = +3 Query: 189 LTLPNCDMEGNYARNQCTGSVCYCVDKYGFQIDKYSFNIGLSANSNCNCARDEVNFKSKK 368 L P C G Y R Q +G+ +CVD + + N C+ + V S+K Sbjct: 1104 LFTPVCLQTGEYVRQQTSGTGAWCVDPSSGEGVPTNTNSSAQCPGLCDALKSRV--LSRK 1161 Query: 369 I-LGLTFSC-ANNGNYNPVQC--VGSSCFCADEIGKPIPGGKVV 488 + LG T C A +G ++PVQC SC+C G+ +PG +VV Sbjct: 1162 VGLGYTPVCEALDGGFSPVQCDLAQGSCWCVLASGEEVPGTRVV 1205
Score = 40.4 bits (93), Expect = 0.003 Identities = 28/103 (27%), Positives = 43/103 (41%), Gaps = 9/103 (8%) Frame = +3 Query: 195 LPNCDMEGNYARNQCT--GSVCYCVDKYGFQIDKYSFNIGLSANSNCNCARDEVNFKSKK 368 +P C +G++ QC G C+CVD G ++ S +G C + Sbjct: 50 VPQCSEDGSFQTVQCQNDGQSCWCVDSDGTEVPG-SRQLGRPTACLSFCQLHKQRILLSS 108 Query: 369 ILGLTFS-----CANNGNYNPVQC--VGSSCFCADEIGKPIPG 476 + T + C ++GNY PVQC C+C D G + G Sbjct: 109 YINSTDALYLPQCQDSGNYAPVQCDLQQVQCWCVDTEGMEVYG 151
Score = 38.5 bits (88), Expect = 0.011 Identities = 14/44 (31%), Positives = 22/44 (50%) Frame = +3 Query: 387 SCANNGNYNPVQCVGSSCFCADEIGKPIPGGKVVNIYNKLTLKC 518 SC G+Y +QC C+C + GK + G +V + + KC Sbjct: 619 SCTAEGSYEDIQCYAGECWCVNSQGKEVEGSRVSGGHPRCPTKC 662
Score = 35.8 bits (81), Expect = 0.072 Identities = 27/96 (28%), Positives = 37/96 (38%), Gaps = 17/96 (17%) Frame = +3 Query: 195 LPNCDMEGNYARNQCTGSVCYCVDKYGFQIDKYSFNIG--LSANSNCNCARDEVNFKSKK 368 +P C EG + QC S CYCVD G I IG S C ++ Sbjct: 684 VPTCTSEGYFLPVQCFNSECYCVDAEGQVIPGTQSTIGEPKLCPSVCQLQAEQAFL---G 740 Query: 369 ILGLTFS---------------CANNGNYNPVQCVG 431 ++G+ S C+ +G + PVQC G Sbjct: 741 VVGVLLSNSSMVPPISSVYIPQCSTSGQWMPVQCDG 776
Score = 34.7 bits (78), Expect = 0.16 Identities = 16/54 (29%), Positives = 27/54 (50%), Gaps = 2/54 (3%) Frame = +3 Query: 327 CNCARDEVNFKSKKILGLTFSCANNGNYNPVQCV--GSSCFCADEIGKPIPGGK 482 C R++ K + + C+ +G++ VQC G SC+C D G +PG + Sbjct: 35 CELQREKAFLKQDEYVP---QCSEDGSFQTVQCQNDGQSCWCVDSDGTEVPGSR 85
Score = 32.3 bits (72), Expect = 0.79 Identities = 24/86 (27%), Positives = 33/86 (38%), Gaps = 7/86 (8%) Frame = +3 Query: 189 LTLPNCDMEGNYARNQC--TGSVCYCVDKYGFQIDKYSFNIGLSANSNCNCARDEVNFKS 362 L LP C GNYA QC C+CVD G ++ G +S Sbjct: 116 LYLPQCQDSGNYAPVQCDLQQVQCWCVDTEGMEV------YGTRQQGRPTRCPRSCEIRS 169 Query: 363 KKIL-----GLTFSCANNGNYNPVQC 425 +++L C +G + PVQC Sbjct: 170 RRLLHGVGDKSPPQCDADGEFMPVQC 195
Score = 30.8 bits (68), Expect = 2.3 Identities = 14/31 (45%), Positives = 18/31 (58%), Gaps = 1/31 (3%) Frame = +3 Query: 387 SCANNGNYNPVQC-VGSSCFCADEIGKPIPG 476 SC +G+Y VQC + C+C D G IPG Sbjct: 319 SCHRDGHYQTVQCQMERMCWCVDAQGIEIPG 349
Score = 30.4 bits (67), Expect = 3.0 Identities = 12/31 (38%), Positives = 19/31 (61%), Gaps = 1/31 (3%) Frame = +3 Query: 195 LPNCDMEGNYARNQC-TGSVCYCVDKYGFQI 284 +P+C +G+Y QC +C+CVD G +I Sbjct: 317 IPSCHRDGHYQTVQCQMERMCWCVDAQGIEI 347
>sp|O08710|THYG_MOUSE Thyroglobulin precursor Length = 2766 Score = 57.0 bits (136), Expect = 3e-08 Identities = 32/99 (32%), Positives = 48/99 (48%), Gaps = 5/99 (5%) Frame = +3 Query: 195 LPNCDMEGNYARNQCTGSVCYCVDKYGFQIDKYSFNIGLS-ANSNCNCARDEV-NFKSKK 368 +P+C G+Y QC C+CVD G ++D G + C R ++ + S + Sbjct: 617 VPSCTAGGSYEDIQCYAGECWCVDSRGKELDGSRVRGGRPRCPTKCEKQRAQMQSLASAQ 676 Query: 369 ILGLTF---SCANNGNYNPVQCVGSSCFCADEIGKPIPG 476 G +F +C G + PVQC S C+C D G+ IPG Sbjct: 677 PAGSSFFVPTCTREGYFLPVQCFNSECYCVDTEGQVIPG 715
Score = 44.7 bits (104), Expect = 2e-04 Identities = 32/104 (30%), Positives = 50/104 (48%), Gaps = 4/104 (3%) Frame = +3 Query: 189 LTLPNCDMEGNYARNQCTGSVCYCVDKYGFQIDKYSFNIGLSANSNCNCARDEVNFKSKK 368 L +P C G Y R Q +G+ +CVD + + N C+ + S+K Sbjct: 1104 LFIPVCLQTGEYVRKQTSGTGTWCVDPASGEGMPVNTNGSAQCPGLCDVLKSRA--LSRK 1161 Query: 369 I-LGLTFSC-ANNGNYNPVQC--VGSSCFCADEIGKPIPGGKVV 488 + LG + C A +G ++PVQC SC+C G+ +PG +VV Sbjct: 1162 VGLGYSPVCEALDGAFSPVQCDLAQGSCWCVLGSGEEVPGTRVV 1205
Score = 38.9 bits (89), Expect = 0.008 Identities = 28/103 (27%), Positives = 43/103 (41%), Gaps = 9/103 (8%) Frame = +3 Query: 195 LPNCDMEGNYARNQCT--GSVCYCVDKYGFQIDKYSFNIGLSANSNCNCARDEVNFKSKK 368 +P C +G++ QC G C+CVD G ++ S +G C + Sbjct: 50 VPQCSEDGSFQTVQCQNDGQSCWCVDSDGREVPG-SRQLGRPTVCLSFCQLHKQRILLGS 108 Query: 369 ILGLTFS-----CANNGNYNPVQC--VGSSCFCADEIGKPIPG 476 + T + C ++GNY PVQC C+C D G + G Sbjct: 109 YINSTDALYLPQCQDSGNYAPVQCDLQRVQCWCVDTEGMEVYG 151
Score = 38.1 bits (87), Expect = 0.014 Identities = 15/44 (34%), Positives = 21/44 (47%) Frame = +3 Query: 387 SCANNGNYNPVQCVGSSCFCADEIGKPIPGGKVVNIYNKLTLKC 518 SC G+Y +QC C+C D GK + G +V + KC Sbjct: 619 SCTAGGSYEDIQCYAGECWCVDSRGKELDGSRVRGGRPRCPTKC 662
Score = 35.8 bits (81), Expect = 0.072 Identities = 16/54 (29%), Positives = 28/54 (51%), Gaps = 2/54 (3%) Frame = +3 Query: 327 CNCARDEVNFKSKKILGLTFSCANNGNYNPVQCV--GSSCFCADEIGKPIPGGK 482 C R++ K + + C+ +G++ VQC G SC+C D G+ +PG + Sbjct: 35 CELQREKAFLKQAEYVP---QCSEDGSFQTVQCQNDGQSCWCVDSDGREVPGSR 85
Score = 34.7 bits (78), Expect = 0.16 Identities = 34/140 (24%), Positives = 51/140 (36%), Gaps = 16/140 (11%) Frame = +3 Query: 60 GRCYNSKKCRGKFVCLFNECQKNPLNTTCLEQYEKVKSSKLLGLTLPNCDMEGNYARNQC 239 G+ + + RG +C+K L + SS +P C EG + QC Sbjct: 643 GKELDGSRVRGGRPRCPTKCEKQRAQMQSLASAQPAGSS----FFVPTCTREGYFLPVQC 698 Query: 240 TGSVCYCVDKYGFQIDKYSFNIGLSANSNCNC-ARDEVNFKSKKILGLTFS--------- 389 S CYCVD G I +G + C + E F ++G+ S Sbjct: 699 FNSECYCVDTEGQVIPGTQSTVGEAKQCPSVCQLQAEQAFLG--VVGVLLSNSSMVPSIS 756 Query: 390 ------CANNGNYNPVQCVG 431 C+ +G + VQC G Sbjct: 757 NVYIPQCSASGQWRHVQCDG 776
Score = 34.3 bits (77), Expect = 0.21 Identities = 30/111 (27%), Positives = 41/111 (36%), Gaps = 15/111 (13%) Frame = +3 Query: 138 TTCLEQYEKVKSSKLLG--------LTLPNCDMEGNYARNQC--TGSVCYCVDKYGFQID 287 T CL + K LLG L LP C GNYA QC C+CVD G ++ Sbjct: 91 TVCLSFCQLHKQRILLGSYINSTDALYLPQCQDSGNYAPVQCDLQRVQCWCVDTEGMEV- 149 Query: 288 KYSFNIGLSANSNCNCARDEVNFKSKKIL-----GLTFSCANNGNYNPVQC 425 G +++++L C +G + PVQC Sbjct: 150 -----YGTRQQGRPTRCPRSCEIRNRRLLHGVGDRSPPQCTADGEFMPVQC 195
Score = 31.2 bits (69), Expect = 1.8 Identities = 12/31 (38%), Positives = 19/31 (61%), Gaps = 1/31 (3%) Frame = +3 Query: 195 LPNCDMEGNYARNQC-TGSVCYCVDKYGFQI 284 +P C +G+Y QC T +C+CVD G ++ Sbjct: 317 IPRCHRDGHYQTVQCQTEGMCWCVDAQGREV 347
Score = 30.8 bits (68), Expect = 2.3 Identities = 12/30 (40%), Positives = 17/30 (56%), Gaps = 1/30 (3%) Frame = +3 Query: 390 CANNGNYNPVQC-VGSSCFCADEIGKPIPG 476 C +G+Y VQC C+C D G+ +PG Sbjct: 320 CHRDGHYQTVQCQTEGMCWCVDAQGREVPG 349
>sp|Q8BKV0|TICN3_MOUSE Testican-3 precursor (SPARC/osteonectin, CWCV, and Kazal-like domains proteoglycan 3) Length = 436 Score = 50.1 bits (118), Expect = 4e-06 Identities = 29/81 (35%), Positives = 40/81 (49%), Gaps = 2/81 (2%) Frame = +3 Query: 108 FNECQKNPLNTTCLEQYEKVKSSKLLGLTLPNCDMEGNYARNQCTGSV--CYCVDKYGFQ 281 F Q P +T ++ KLLG +P CD +G Y QC GSV C+CVD+YG + Sbjct: 309 FQRQQDPPCHTELSNIQKRQGIKKLLGQYIPLCDEDGYYKPTQCHGSVGQCWCVDRYGNE 368 Query: 282 IDKYSFNIGLSANSNCNCARD 344 + +G N +CA D Sbjct: 369 V------VGSRINGVADCAID 383
Score = 35.4 bits (80), Expect = 0.094 Identities = 17/44 (38%), Positives = 23/44 (52%), Gaps = 3/44 (6%) Frame = +3 Query: 363 KKILGLTFS-CANNGNYNPVQCVGS--SCFCADEIGKPIPGGKV 485 KK+LG C +G Y P QC GS C+C D G + G ++ Sbjct: 331 KKLLGQYIPLCDEDGYYKPTQCHGSVGQCWCVDRYGNEVVGSRI 374
>sp|Q9BQ16|TICN3_HUMAN Testican-3 precursor (SPARC/osteonectin, CWCV, and Kazal-like domains proteoglycan 3) Length = 436 Score = 49.3 bits (116), Expect = 6e-06 Identities = 31/84 (36%), Positives = 44/84 (52%), Gaps = 3/84 (3%) Frame = +3 Query: 102 CLFNECQKNPLNTTCLEQYEKVKS-SKLLGLTLPNCDMEGNYARNQCTGSV--CYCVDKY 272 C + Q++P T L +K + KLLG +P CD +G Y QC GSV C+CVD+Y Sbjct: 306 CYCFQRQQDPPCQTELSNIQKRQGVKKLLGQYIPLCDEDGYYKPTQCHGSVGQCWCVDRY 365 Query: 273 GFQIDKYSFNIGLSANSNCNCARD 344 G ++ +G N +CA D Sbjct: 366 GNEV------MGSRINGVADCAID 383
Score = 35.4 bits (80), Expect = 0.094 Identities = 17/44 (38%), Positives = 23/44 (52%), Gaps = 3/44 (6%) Frame = +3 Query: 363 KKILGLTFS-CANNGNYNPVQCVGS--SCFCADEIGKPIPGGKV 485 KK+LG C +G Y P QC GS C+C D G + G ++ Sbjct: 331 KKLLGQYIPLCDEDGYYKPTQCHGSVGQCWCVDRYGNEVMGSRI 374
>sp|Q5RD69|TICN3_PONPY Testican-3 precursor (SPARC/osteonectin, CWCV, and Kazal-like domains proteoglycan 3) Length = 436 Score = 49.3 bits (116), Expect = 6e-06 Identities = 31/84 (36%), Positives = 44/84 (52%), Gaps = 3/84 (3%) Frame = +3 Query: 102 CLFNECQKNPLNTTCLEQYEKVKS-SKLLGLTLPNCDMEGNYARNQCTGSV--CYCVDKY 272 C + Q++P T L +K + KLLG +P CD +G Y QC GSV C+CVD+Y Sbjct: 306 CYCFQRQQDPPCQTELSNIQKRQGVKKLLGQYIPLCDEDGYYKPTQCHGSVGQCWCVDRY 365 Query: 273 GFQIDKYSFNIGLSANSNCNCARD 344 G ++ +G N +CA D Sbjct: 366 GNEV------MGSRINGVADCAID 383
Score = 35.4 bits (80), Expect = 0.094 Identities = 17/44 (38%), Positives = 23/44 (52%), Gaps = 3/44 (6%) Frame = +3 Query: 363 KKILGLTFS-CANNGNYNPVQCVGS--SCFCADEIGKPIPGGKV 485 KK+LG C +G Y P QC GS C+C D G + G ++ Sbjct: 331 KKLLGQYIPLCDEDGYYKPTQCHGSVGQCWCVDRYGNEVMGSRI 374
>sp|Q62288|TICN1_MOUSE Testican-1 precursor (SPOCK protein) Length = 442 Score = 48.5 bits (114), Expect = 1e-05 Identities = 23/62 (37%), Positives = 32/62 (51%), Gaps = 6/62 (9%) Frame = +3 Query: 117 CQKNPLNTTCLEQYEKV----KSSKLLGLTLPNCDMEGNYARNQCTGSV--CYCVDKYGF 278 C + P C + ++ K LLG +P C+ EG Y QC GS C+CVDKYG Sbjct: 307 CFQKPAGLPCQNEMNRIQKLSKGKSLLGAFIPRCNEEGYYKATQCHGSTGQCWCVDKYGN 366 Query: 279 QI 284 ++ Sbjct: 367 EL 368
Database: Non-redundant SwissProt sequences Posted date: Dec 6, 2005 7:40 AM Number of letters in database: 68,354,980 Number of sequences in database: 184,735 Database: swissprot.01 Posted date: Dec 6, 2005 8:18 AM Number of letters in database: 66,202,850 Number of sequences in database: 184,431 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 61,874,545 Number of Sequences: 369166 Number of extensions: 1291696 Number of successful extensions: 3263 Number of sequences better than 10.0: 10 Number of HSP's better than 10.0 without gapping: 3056 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 3222 length of database: 68,354,980 effective HSP length: 104 effective length of database: 49,142,540 effective search space used: 3882260660 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)