Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_026_H23
(544 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P01267|THYG_BOVIN Thyroglobulin precursor 62 7e-10
sp|P31226|SAX_RANCA Saxiphilin precursor (SAX) 59 6e-09
sp|P81439|EQST_ACTEQ Equistatin 59 6e-09
sp|P01266|THYG_HUMAN Thyroglobulin precursor 58 1e-08
sp|P06882|THYG_RAT Thyroglobulin precursor 58 2e-08
sp|O08710|THYG_MOUSE Thyroglobulin precursor 57 3e-08
sp|Q8BKV0|TICN3_MOUSE Testican-3 precursor (SPARC/osteonect... 50 4e-06
sp|Q9BQ16|TICN3_HUMAN Testican-3 precursor (SPARC/osteonect... 49 6e-06
sp|Q5RD69|TICN3_PONPY Testican-3 precursor (SPARC/osteonect... 49 6e-06
sp|Q62288|TICN1_MOUSE Testican-1 precursor (SPOCK protein) 49 1e-05
>sp|P01267|THYG_BOVIN Thyroglobulin precursor
Length = 2769
Score = 62.4 bits (150), Expect = 7e-10
Identities = 33/104 (31%), Positives = 48/104 (46%), Gaps = 8/104 (7%)
Frame = +3
Query: 183 LTLPNCDMEGNYARNQCTGSVCYCVDKYGFQIDKYSFNIGLSANSNCNCARDEVNFKSKK 362
L +P C EG+Y QC C+CVD G ++ G C ++ + +
Sbjct: 614 LFVPACTAEGSYEEVQCFAGDCWCVDAQGRELAGSRVRGG---RPRCPTECEKQRARMQS 670
Query: 363 ILG--------LTFSCANNGNYNPVQCVGSSCFCADEIGKPIPG 470
+LG +C + GN+ PVQC S C+C D G+PIPG
Sbjct: 671 LLGSQPAGSSLFVPACTSKGNFLPVQCFNSECYCVDTEGQPIPG 714
Score = 40.4 bits (93), Expect = 0.003
Identities = 29/102 (28%), Positives = 47/102 (46%), Gaps = 3/102 (2%)
Frame = +3
Query: 183 LTLPNCDMEGNYARNQCTGSVCYCVDKYGFQIDKYSFNIGLSANSNCNCARDEVNFKSKK 362
L +P C G +AR Q + + +CVD + N S C + V + +
Sbjct: 1103 LFIPTCLETGEFARLQASEAGTWCVDPASGEGVPPGTNSSAQCPSLCEVLQSGVPSR-RT 1161
Query: 363 ILGLTFSC-ANNGNYNPVQC--VGSSCFCADEIGKPIPGGKV 479
G + +C A +G ++PVQC SC+C G+ +PG +V
Sbjct: 1162 SPGYSPACRAEDGGFSPVQCDPAQGSCWCVLGSGEEVPGTRV 1203
Score = 39.7 bits (91), Expect = 0.005
Identities = 37/141 (26%), Positives = 52/141 (36%), Gaps = 14/141 (9%)
Frame = +3
Query: 45 NVSGRCYNSKKCRGKFVCLFNECQKNPLNTTCLEQYEKVKSSKLLGLTLPNCDMEGNYAR 224
+ GR + RG EC+K L + SS L +P C +GN+
Sbjct: 639 DAQGRELAGSRVRGGRPRCPTECEKQRARMQSLLGSQPAGSS----LFVPACTSKGNFLP 694
Query: 225 NQCTGSVCYCVDKYGFQIDKYSFNIG--LSANSNCNCARDEVNFKSKKILGLTFS----- 383
QC S CYCVD G I +G S C + + + L S
Sbjct: 695 VQCFNSECYCVDTEGQPIPGTRSALGEPKKCPSPCQLQAERAFLGTVRTLVSNPSTLPAL 754
Query: 384 -------CANNGNYNPVQCVG 425
C+ +G ++PVQC G
Sbjct: 755 SSIYIPQCSASGQWSPVQCDG 775
Score = 39.3 bits (90), Expect = 0.006
Identities = 28/103 (27%), Positives = 48/103 (46%), Gaps = 9/103 (8%)
Frame = +3
Query: 189 LPNCDMEGNYARNQC--TGSVCYCVDKYGFQIDKYSFNIGLSAN--SNCNCARDEV---N 347
+P C +G++ QC G+ C+CVD G ++ S G A S C + ++ +
Sbjct: 49 VPQCAEDGSFQTVQCGKDGASCWCVDADGREVPG-SRQPGRPAACLSFCQLQKQQILLSS 107
Query: 348 FKSKKILGLTFSCANNGNYNPVQC--VGSSCFCADEIGKPIPG 470
+ + C ++G+Y+PVQC C+C D G + G
Sbjct: 108 YINSTATSYLPQCQDSGDYSPVQCDLRRRQCWCVDAEGMEVYG 150
Score = 36.2 bits (82), Expect = 0.053
Identities = 14/33 (42%), Positives = 22/33 (66%), Gaps = 2/33 (6%)
Frame = +3
Query: 384 CANNGNYNPVQCV--GSSCFCADEIGKPIPGGK 476
CA +G++ VQC G+SC+C D G+ +PG +
Sbjct: 52 CAEDGSFQTVQCGKDGASCWCVDADGREVPGSR 84
Score = 35.0 bits (79), Expect = 0.12
Identities = 12/33 (36%), Positives = 18/33 (54%)
Frame = +3
Query: 381 SCANNGNYNPVQCVGSSCFCADEIGKPIPGGKV 479
+C G+Y VQC C+C D G+ + G +V
Sbjct: 618 ACTAEGSYEEVQCFAGDCWCVDAQGRELAGSRV 650
Score = 32.3 bits (72), Expect = 0.76
Identities = 14/31 (45%), Positives = 17/31 (54%), Gaps = 1/31 (3%)
Frame = +3
Query: 381 SCANNGNYNPVQCV-GSSCFCADEIGKPIPG 470
SC +G Y QC G C+C D G+ IPG
Sbjct: 318 SCHPDGEYQAAQCQQGGPCWCVDSRGQEIPG 348
>sp|P31226|SAX_RANCA Saxiphilin precursor (SAX)
Length = 844
Score = 59.3 bits (142), Expect = 6e-09
Identities = 41/128 (32%), Positives = 60/128 (46%), Gaps = 15/128 (11%)
Frame = +3
Query: 138 CLEQYEKVKSSKLLGLTLPNCDMEGNYARNQCTGSV--CYCVDKYGFQIDKYSFNIGLSA 311
CL++ ++ + K++G +P CD +GNY QC GS C+CV+ G +K S
Sbjct: 110 CLKERQQALAKKMIGHYIPQCDEKGNYQPQQCHGSTGHCWCVNAMG---EKISGTNTPPG 166
Query: 312 NSNCNCARDEVNFKSK----------KILG-LTFSCANNGNYNPVQCVGSS--CFCADEI 452
+ C R E+ K K+LG C GNY P Q GS+ +C + I
Sbjct: 167 QTRATCERHELPKCLKERQVALGGDEKVLGRFVPQCDEKGNYEPQQFHGSTGYSWCVNAI 226
Query: 453 GKPIPGGK 476
G+ I G K
Sbjct: 227 GEEIAGTK 234
>sp|P81439|EQST_ACTEQ Equistatin
Length = 199
Score = 59.3 bits (142), Expect = 6e-09
Identities = 36/103 (34%), Positives = 52/103 (50%), Gaps = 7/103 (6%)
Frame = +3
Query: 192 PNCDMEGNYARNQCTGS--VCYCVDKYGFQIDKYSFNIGLSAN---SNCNCARDEVNFKS 356
P+C +G++ QC S CYCVDK G +++ S S C AR + + S
Sbjct: 90 PSCKADGSFDEVQCCASNGECYCVDKKGKELEGTRQKGRPSCERHLSPCEEARLQAHSNS 149
Query: 357 KKILGLTFSCANNGNYNPVQCVGSS--CFCADEIGKPIPGGKV 479
++ C +G+YNPVQC S+ C+C DE G +PG V
Sbjct: 150 LRVGMFVPQCLEDGSYNPVQCWPSTGYCWCVDEGGVKVPGSDV 192
Score = 53.9 bits (128), Expect = 2e-07
Identities = 33/123 (26%), Positives = 58/123 (47%), Gaps = 14/123 (11%)
Frame = +3
Query: 144 EQYEKVKSSKLLGLTLPNCDMEGNYARNQCTGSV--CYCVDKYGFQIDKYSFNIGLSANS 317
+Q + +S L+G +P C G + QC GS C+CVD+ G +I +G
Sbjct: 6 QQLQASANSGLIGAYVPQCKETGEFEEKQCWGSTGYCWCVDEDGKEI------LGTKIRG 59
Query: 318 NCNCARDEVNFKSKKILGLTF----------SCANNGNYNPVQCVGSS--CFCADEIGKP 461
+ +C+R + +++ SC +G+++ VQC S+ C+C D+ GK
Sbjct: 60 SPDCSRRKAALTLCQMMQAIIVNVPGWCGPPSCKADGSFDEVQCCASNGECYCVDKKGKE 119
Query: 462 IPG 470
+ G
Sbjct: 120 LEG 122
Score = 30.4 bits (67), Expect = 2.9
Identities = 17/50 (34%), Positives = 28/50 (56%), Gaps = 3/50 (6%)
Frame = +3
Query: 138 CLEQYEKVKSSKL-LGLTLPNCDMEGNYARNQCTGSV--CYCVDKYGFQI 278
C E + S+ L +G+ +P C +G+Y QC S C+CVD+ G ++
Sbjct: 138 CEEARLQAHSNSLRVGMFVPQCLEDGSYNPVQCWPSTGYCWCVDEGGVKV 187
>sp|P01266|THYG_HUMAN Thyroglobulin precursor
Length = 2768
Score = 58.2 bits (139), Expect = 1e-08
Identities = 31/102 (30%), Positives = 49/102 (48%), Gaps = 6/102 (5%)
Frame = +3
Query: 183 LTLPNCDMEGNYARNQCTGSVCYCVDKYGFQIDKYSFNIGLSANSNCNCARDEVNFKS-- 356
L +P+C EG+Y QC C+CV+ +G ++ G +C + +S
Sbjct: 615 LFVPSCTTEGSYEDVQCFSGECWCVNSWGKELPGSRVRGG-QPRCPTDCEKQRARMQSLM 673
Query: 357 -KKILGLTF---SCANNGNYNPVQCVGSSCFCADEIGKPIPG 470
+ G T +C + G++ PVQC S C+C D G+ IPG
Sbjct: 674 GSQPAGSTLFVPACTSEGHFLPVQCFNSECYCVDAEGQAIPG 715
Score = 47.4 bits (111), Expect = 2e-05
Identities = 31/102 (30%), Positives = 49/102 (48%), Gaps = 3/102 (2%)
Frame = +3
Query: 183 LTLPNCDMEGNYARNQCTGSVCYCVDKYGFQIDKYSFNIGLSANSNCNCARDEVNFKSKK 362
L +P C G YAR Q +G+ +CVD + + + S CN + V +
Sbjct: 1103 LFVPACLETGEYARLQASGAGTWCVDPASGEELRPGSSSSAQCPSLCNVLKSGV-LSRRV 1161
Query: 363 ILGLTFSC-ANNGNYNPVQC--VGSSCFCADEIGKPIPGGKV 479
G +C A +G ++PVQC SC+C + G+ +PG +V
Sbjct: 1162 SPGYVPACRAEDGGFSPVQCDQAQGSCWCVMDSGEEVPGTRV 1203
Score = 39.7 bits (91), Expect = 0.005
Identities = 14/33 (42%), Positives = 19/33 (57%)
Frame = +3
Query: 381 SCANNGNYNPVQCVGSSCFCADEIGKPIPGGKV 479
SC G+Y VQC C+C + GK +PG +V
Sbjct: 619 SCTTEGSYEDVQCFSGECWCVNSWGKELPGSRV 651
Score = 34.3 bits (77), Expect = 0.20
Identities = 24/102 (23%), Positives = 43/102 (42%), Gaps = 8/102 (7%)
Frame = +3
Query: 189 LPNCDMEGNYARNQCT--GSVCYCVDKYGFQI-DKYSFNIGLSANSNCNCARDEV---NF 350
+P C +G++ QC G C+CV G ++ ++ S C + ++ +
Sbjct: 49 VPQCAEDGSFQTVQCQNDGRSCWCVGANGSEVLGSRQPGRPVACLSFCQLQKQQILLSGY 108
Query: 351 KSKKILGLTFSCANNGNYNPVQC--VGSSCFCADEIGKPIPG 470
+ C ++G+Y PVQC C+C D G + G
Sbjct: 109 INSTDTSYLPQCQDSGDYAPVQCDVQQVQCWCVDAEGMEVYG 150
Score = 31.6 bits (70), Expect = 1.3
Identities = 14/31 (45%), Positives = 17/31 (54%), Gaps = 1/31 (3%)
Frame = +3
Query: 381 SCANNGNYNPVQC-VGSSCFCADEIGKPIPG 470
SC NG+Y VQC C+C D GK + G
Sbjct: 318 SCRRNGDYQAVQCQTEGPCWCVDAQGKEMHG 348
Score = 30.0 bits (66), Expect = 3.8
Identities = 27/106 (25%), Positives = 40/106 (37%), Gaps = 17/106 (16%)
Frame = +3
Query: 180 GLTLPNCDMEGNYARNQCTGSV--CYCVDKYG-----------FQIDKYSFNIGLSAN-- 314
G +P CD G++ QC C+CVD+ G QI + S
Sbjct: 1025 GPYMPQCDAFGSWEPVQCHAGTGHCWCVDEKGGFIPGSLTARSLQIPQCPTTCEKSRTSG 1084
Query: 315 --SNCNCARDEVNFKSKKILGLTFSCANNGNYNPVQCVGSSCFCAD 446
S+ AR + N K + +C G Y +Q G+ +C D
Sbjct: 1085 LLSSWKQARSQENPSPKDL--FVPACLETGEYARLQASGAGTWCVD 1128
Score = 29.6 bits (65), Expect = 4.9
Identities = 14/31 (45%), Positives = 18/31 (58%), Gaps = 2/31 (6%)
Frame = +3
Query: 384 CANNGNYNPVQCVGSS--CFCADEIGKPIPG 470
C G++ PVQC + C+C DE G IPG
Sbjct: 1031 CDAFGSWEPVQCHAGTGHCWCVDEKGGFIPG 1061
>sp|P06882|THYG_RAT Thyroglobulin precursor
Length = 2768
Score = 57.8 bits (138), Expect = 2e-08
Identities = 31/99 (31%), Positives = 50/99 (50%), Gaps = 5/99 (5%)
Frame = +3
Query: 189 LPNCDMEGNYARNQCTGSVCYCVDKYGFQIDKYSFNIGLS-ANSNCNCARDEV-NFKSKK 362
+P+C EG+Y QC C+CV+ G +++ + G + C R ++ N +
Sbjct: 617 VPSCTAEGSYEDIQCYAGECWCVNSQGKEVEGSRVSGGHPRCPTKCEKQRAQMQNLAGAQ 676
Query: 363 ILGLTF---SCANNGNYNPVQCVGSSCFCADEIGKPIPG 470
G +F +C + G + PVQC S C+C D G+ IPG
Sbjct: 677 PAGSSFFVPTCTSEGYFLPVQCFNSECYCVDAEGQVIPG 715
Score = 48.9 bits (115), Expect = 8e-06
Identities = 34/104 (32%), Positives = 50/104 (48%), Gaps = 4/104 (3%)
Frame = +3
Query: 183 LTLPNCDMEGNYARNQCTGSVCYCVDKYGFQIDKYSFNIGLSANSNCNCARDEVNFKSKK 362
L P C G Y R Q +G+ +CVD + + N C+ + V S+K
Sbjct: 1104 LFTPVCLQTGEYVRQQTSGTGAWCVDPSSGEGVPTNTNSSAQCPGLCDALKSRV--LSRK 1161
Query: 363 I-LGLTFSC-ANNGNYNPVQC--VGSSCFCADEIGKPIPGGKVV 482
+ LG T C A +G ++PVQC SC+C G+ +PG +VV
Sbjct: 1162 VGLGYTPVCEALDGGFSPVQCDLAQGSCWCVLASGEEVPGTRVV 1205
Score = 40.4 bits (93), Expect = 0.003
Identities = 28/103 (27%), Positives = 43/103 (41%), Gaps = 9/103 (8%)
Frame = +3
Query: 189 LPNCDMEGNYARNQCT--GSVCYCVDKYGFQIDKYSFNIGLSANSNCNCARDEVNFKSKK 362
+P C +G++ QC G C+CVD G ++ S +G C +
Sbjct: 50 VPQCSEDGSFQTVQCQNDGQSCWCVDSDGTEVPG-SRQLGRPTACLSFCQLHKQRILLSS 108
Query: 363 ILGLTFS-----CANNGNYNPVQC--VGSSCFCADEIGKPIPG 470
+ T + C ++GNY PVQC C+C D G + G
Sbjct: 109 YINSTDALYLPQCQDSGNYAPVQCDLQQVQCWCVDTEGMEVYG 151
Score = 38.5 bits (88), Expect = 0.011
Identities = 14/44 (31%), Positives = 22/44 (50%)
Frame = +3
Query: 381 SCANNGNYNPVQCVGSSCFCADEIGKPIPGGKVVNIYNKLTLKC 512
SC G+Y +QC C+C + GK + G +V + + KC
Sbjct: 619 SCTAEGSYEDIQCYAGECWCVNSQGKEVEGSRVSGGHPRCPTKC 662
Score = 35.8 bits (81), Expect = 0.069
Identities = 27/96 (28%), Positives = 37/96 (38%), Gaps = 17/96 (17%)
Frame = +3
Query: 189 LPNCDMEGNYARNQCTGSVCYCVDKYGFQIDKYSFNIG--LSANSNCNCARDEVNFKSKK 362
+P C EG + QC S CYCVD G I IG S C ++
Sbjct: 684 VPTCTSEGYFLPVQCFNSECYCVDAEGQVIPGTQSTIGEPKLCPSVCQLQAEQAFL---G 740
Query: 363 ILGLTFS---------------CANNGNYNPVQCVG 425
++G+ S C+ +G + PVQC G
Sbjct: 741 VVGVLLSNSSMVPPISSVYIPQCSTSGQWMPVQCDG 776
Score = 34.7 bits (78), Expect = 0.15
Identities = 16/54 (29%), Positives = 27/54 (50%), Gaps = 2/54 (3%)
Frame = +3
Query: 321 CNCARDEVNFKSKKILGLTFSCANNGNYNPVQCV--GSSCFCADEIGKPIPGGK 476
C R++ K + + C+ +G++ VQC G SC+C D G +PG +
Sbjct: 35 CELQREKAFLKQDEYVP---QCSEDGSFQTVQCQNDGQSCWCVDSDGTEVPGSR 85
Score = 32.3 bits (72), Expect = 0.76
Identities = 24/86 (27%), Positives = 33/86 (38%), Gaps = 7/86 (8%)
Frame = +3
Query: 183 LTLPNCDMEGNYARNQC--TGSVCYCVDKYGFQIDKYSFNIGLSANSNCNCARDEVNFKS 356
L LP C GNYA QC C+CVD G ++ G +S
Sbjct: 116 LYLPQCQDSGNYAPVQCDLQQVQCWCVDTEGMEV------YGTRQQGRPTRCPRSCEIRS 169
Query: 357 KKIL-----GLTFSCANNGNYNPVQC 419
+++L C +G + PVQC
Sbjct: 170 RRLLHGVGDKSPPQCDADGEFMPVQC 195
Score = 30.8 bits (68), Expect = 2.2
Identities = 14/31 (45%), Positives = 18/31 (58%), Gaps = 1/31 (3%)
Frame = +3
Query: 381 SCANNGNYNPVQC-VGSSCFCADEIGKPIPG 470
SC +G+Y VQC + C+C D G IPG
Sbjct: 319 SCHRDGHYQTVQCQMERMCWCVDAQGIEIPG 349
Score = 30.4 bits (67), Expect = 2.9
Identities = 12/31 (38%), Positives = 19/31 (61%), Gaps = 1/31 (3%)
Frame = +3
Query: 189 LPNCDMEGNYARNQC-TGSVCYCVDKYGFQI 278
+P+C +G+Y QC +C+CVD G +I
Sbjct: 317 IPSCHRDGHYQTVQCQMERMCWCVDAQGIEI 347
>sp|O08710|THYG_MOUSE Thyroglobulin precursor
Length = 2766
Score = 57.0 bits (136), Expect = 3e-08
Identities = 32/99 (32%), Positives = 48/99 (48%), Gaps = 5/99 (5%)
Frame = +3
Query: 189 LPNCDMEGNYARNQCTGSVCYCVDKYGFQIDKYSFNIGLS-ANSNCNCARDEV-NFKSKK 362
+P+C G+Y QC C+CVD G ++D G + C R ++ + S +
Sbjct: 617 VPSCTAGGSYEDIQCYAGECWCVDSRGKELDGSRVRGGRPRCPTKCEKQRAQMQSLASAQ 676
Query: 363 ILGLTF---SCANNGNYNPVQCVGSSCFCADEIGKPIPG 470
G +F +C G + PVQC S C+C D G+ IPG
Sbjct: 677 PAGSSFFVPTCTREGYFLPVQCFNSECYCVDTEGQVIPG 715
Score = 44.7 bits (104), Expect = 1e-04
Identities = 32/104 (30%), Positives = 50/104 (48%), Gaps = 4/104 (3%)
Frame = +3
Query: 183 LTLPNCDMEGNYARNQCTGSVCYCVDKYGFQIDKYSFNIGLSANSNCNCARDEVNFKSKK 362
L +P C G Y R Q +G+ +CVD + + N C+ + S+K
Sbjct: 1104 LFIPVCLQTGEYVRKQTSGTGTWCVDPASGEGMPVNTNGSAQCPGLCDVLKSRA--LSRK 1161
Query: 363 I-LGLTFSC-ANNGNYNPVQC--VGSSCFCADEIGKPIPGGKVV 482
+ LG + C A +G ++PVQC SC+C G+ +PG +VV
Sbjct: 1162 VGLGYSPVCEALDGAFSPVQCDLAQGSCWCVLGSGEEVPGTRVV 1205
Score = 38.9 bits (89), Expect = 0.008
Identities = 28/103 (27%), Positives = 43/103 (41%), Gaps = 9/103 (8%)
Frame = +3
Query: 189 LPNCDMEGNYARNQCT--GSVCYCVDKYGFQIDKYSFNIGLSANSNCNCARDEVNFKSKK 362
+P C +G++ QC G C+CVD G ++ S +G C +
Sbjct: 50 VPQCSEDGSFQTVQCQNDGQSCWCVDSDGREVPG-SRQLGRPTVCLSFCQLHKQRILLGS 108
Query: 363 ILGLTFS-----CANNGNYNPVQC--VGSSCFCADEIGKPIPG 470
+ T + C ++GNY PVQC C+C D G + G
Sbjct: 109 YINSTDALYLPQCQDSGNYAPVQCDLQRVQCWCVDTEGMEVYG 151
Score = 38.1 bits (87), Expect = 0.014
Identities = 15/44 (34%), Positives = 21/44 (47%)
Frame = +3
Query: 381 SCANNGNYNPVQCVGSSCFCADEIGKPIPGGKVVNIYNKLTLKC 512
SC G+Y +QC C+C D GK + G +V + KC
Sbjct: 619 SCTAGGSYEDIQCYAGECWCVDSRGKELDGSRVRGGRPRCPTKC 662
Score = 35.8 bits (81), Expect = 0.069
Identities = 16/54 (29%), Positives = 28/54 (51%), Gaps = 2/54 (3%)
Frame = +3
Query: 321 CNCARDEVNFKSKKILGLTFSCANNGNYNPVQCV--GSSCFCADEIGKPIPGGK 476
C R++ K + + C+ +G++ VQC G SC+C D G+ +PG +
Sbjct: 35 CELQREKAFLKQAEYVP---QCSEDGSFQTVQCQNDGQSCWCVDSDGREVPGSR 85
Score = 34.7 bits (78), Expect = 0.15
Identities = 34/140 (24%), Positives = 51/140 (36%), Gaps = 16/140 (11%)
Frame = +3
Query: 54 GRCYNSKKCRGKFVCLFNECQKNPLNTTCLEQYEKVKSSKLLGLTLPNCDMEGNYARNQC 233
G+ + + RG +C+K L + SS +P C EG + QC
Sbjct: 643 GKELDGSRVRGGRPRCPTKCEKQRAQMQSLASAQPAGSS----FFVPTCTREGYFLPVQC 698
Query: 234 TGSVCYCVDKYGFQIDKYSFNIGLSANSNCNC-ARDEVNFKSKKILGLTFS--------- 383
S CYCVD G I +G + C + E F ++G+ S
Sbjct: 699 FNSECYCVDTEGQVIPGTQSTVGEAKQCPSVCQLQAEQAFLG--VVGVLLSNSSMVPSIS 756
Query: 384 ------CANNGNYNPVQCVG 425
C+ +G + VQC G
Sbjct: 757 NVYIPQCSASGQWRHVQCDG 776
Score = 34.3 bits (77), Expect = 0.20
Identities = 30/111 (27%), Positives = 41/111 (36%), Gaps = 15/111 (13%)
Frame = +3
Query: 132 TTCLEQYEKVKSSKLLG--------LTLPNCDMEGNYARNQC--TGSVCYCVDKYGFQID 281
T CL + K LLG L LP C GNYA QC C+CVD G ++
Sbjct: 91 TVCLSFCQLHKQRILLGSYINSTDALYLPQCQDSGNYAPVQCDLQRVQCWCVDTEGMEV- 149
Query: 282 KYSFNIGLSANSNCNCARDEVNFKSKKIL-----GLTFSCANNGNYNPVQC 419
G +++++L C +G + PVQC
Sbjct: 150 -----YGTRQQGRPTRCPRSCEIRNRRLLHGVGDRSPPQCTADGEFMPVQC 195
Score = 31.2 bits (69), Expect = 1.7
Identities = 12/31 (38%), Positives = 19/31 (61%), Gaps = 1/31 (3%)
Frame = +3
Query: 189 LPNCDMEGNYARNQC-TGSVCYCVDKYGFQI 278
+P C +G+Y QC T +C+CVD G ++
Sbjct: 317 IPRCHRDGHYQTVQCQTEGMCWCVDAQGREV 347
Score = 30.8 bits (68), Expect = 2.2
Identities = 12/30 (40%), Positives = 17/30 (56%), Gaps = 1/30 (3%)
Frame = +3
Query: 384 CANNGNYNPVQC-VGSSCFCADEIGKPIPG 470
C +G+Y VQC C+C D G+ +PG
Sbjct: 320 CHRDGHYQTVQCQTEGMCWCVDAQGREVPG 349
>sp|Q8BKV0|TICN3_MOUSE Testican-3 precursor (SPARC/osteonectin, CWCV, and Kazal-like
domains proteoglycan 3)
Length = 436
Score = 50.1 bits (118), Expect = 4e-06
Identities = 29/81 (35%), Positives = 40/81 (49%), Gaps = 2/81 (2%)
Frame = +3
Query: 102 FNECQKNPLNTTCLEQYEKVKSSKLLGLTLPNCDMEGNYARNQCTGSV--CYCVDKYGFQ 275
F Q P +T ++ KLLG +P CD +G Y QC GSV C+CVD+YG +
Sbjct: 309 FQRQQDPPCHTELSNIQKRQGIKKLLGQYIPLCDEDGYYKPTQCHGSVGQCWCVDRYGNE 368
Query: 276 IDKYSFNIGLSANSNCNCARD 338
+ +G N +CA D
Sbjct: 369 V------VGSRINGVADCAID 383
Score = 35.4 bits (80), Expect = 0.090
Identities = 17/44 (38%), Positives = 23/44 (52%), Gaps = 3/44 (6%)
Frame = +3
Query: 357 KKILGLTFS-CANNGNYNPVQCVGS--SCFCADEIGKPIPGGKV 479
KK+LG C +G Y P QC GS C+C D G + G ++
Sbjct: 331 KKLLGQYIPLCDEDGYYKPTQCHGSVGQCWCVDRYGNEVVGSRI 374
>sp|Q9BQ16|TICN3_HUMAN Testican-3 precursor (SPARC/osteonectin, CWCV, and Kazal-like
domains proteoglycan 3)
Length = 436
Score = 49.3 bits (116), Expect = 6e-06
Identities = 31/84 (36%), Positives = 44/84 (52%), Gaps = 3/84 (3%)
Frame = +3
Query: 96 CLFNECQKNPLNTTCLEQYEKVKS-SKLLGLTLPNCDMEGNYARNQCTGSV--CYCVDKY 266
C + Q++P T L +K + KLLG +P CD +G Y QC GSV C+CVD+Y
Sbjct: 306 CYCFQRQQDPPCQTELSNIQKRQGVKKLLGQYIPLCDEDGYYKPTQCHGSVGQCWCVDRY 365
Query: 267 GFQIDKYSFNIGLSANSNCNCARD 338
G ++ +G N +CA D
Sbjct: 366 GNEV------MGSRINGVADCAID 383
Score = 35.4 bits (80), Expect = 0.090
Identities = 17/44 (38%), Positives = 23/44 (52%), Gaps = 3/44 (6%)
Frame = +3
Query: 357 KKILGLTFS-CANNGNYNPVQCVGS--SCFCADEIGKPIPGGKV 479
KK+LG C +G Y P QC GS C+C D G + G ++
Sbjct: 331 KKLLGQYIPLCDEDGYYKPTQCHGSVGQCWCVDRYGNEVMGSRI 374
>sp|Q5RD69|TICN3_PONPY Testican-3 precursor (SPARC/osteonectin, CWCV, and Kazal-like
domains proteoglycan 3)
Length = 436
Score = 49.3 bits (116), Expect = 6e-06
Identities = 31/84 (36%), Positives = 44/84 (52%), Gaps = 3/84 (3%)
Frame = +3
Query: 96 CLFNECQKNPLNTTCLEQYEKVKS-SKLLGLTLPNCDMEGNYARNQCTGSV--CYCVDKY 266
C + Q++P T L +K + KLLG +P CD +G Y QC GSV C+CVD+Y
Sbjct: 306 CYCFQRQQDPPCQTELSNIQKRQGVKKLLGQYIPLCDEDGYYKPTQCHGSVGQCWCVDRY 365
Query: 267 GFQIDKYSFNIGLSANSNCNCARD 338
G ++ +G N +CA D
Sbjct: 366 GNEV------MGSRINGVADCAID 383
Score = 35.4 bits (80), Expect = 0.090
Identities = 17/44 (38%), Positives = 23/44 (52%), Gaps = 3/44 (6%)
Frame = +3
Query: 357 KKILGLTFS-CANNGNYNPVQCVGS--SCFCADEIGKPIPGGKV 479
KK+LG C +G Y P QC GS C+C D G + G ++
Sbjct: 331 KKLLGQYIPLCDEDGYYKPTQCHGSVGQCWCVDRYGNEVMGSRI 374
>sp|Q62288|TICN1_MOUSE Testican-1 precursor (SPOCK protein)
Length = 442
Score = 48.5 bits (114), Expect = 1e-05
Identities = 23/62 (37%), Positives = 32/62 (51%), Gaps = 6/62 (9%)
Frame = +3
Query: 111 CQKNPLNTTCLEQYEKV----KSSKLLGLTLPNCDMEGNYARNQCTGSV--CYCVDKYGF 272
C + P C + ++ K LLG +P C+ EG Y QC GS C+CVDKYG
Sbjct: 307 CFQKPAGLPCQNEMNRIQKLSKGKSLLGAFIPRCNEEGYYKATQCHGSTGQCWCVDKYGN 366
Query: 273 QI 278
++
Sbjct: 367 EL 368
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 61,857,316
Number of Sequences: 369166
Number of extensions: 1290795
Number of successful extensions: 3253
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 3048
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3212
length of database: 68,354,980
effective HSP length: 104
effective length of database: 49,142,540
effective search space used: 3734833040
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)