DrC_00535
- Cluster detail
- GO Category : Not Available
- Consensus Sequence :
BLASTX 2.2.13 [Nov-27-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= DrC_00535 (1007 letters) Database: Non-redundant SwissProt sequences 184,735 sequences; 68,354,980 total letters Score E Sequences producing significant alignments: (bits) Value sp|Q09543|2AAA_CAEEL Probable protein phosphatase PP2A regu... 59 2e-08 sp|P54612|2AAA_PIG Serine/threonine protein phosphatase 2A,... 47 7e-05 sp|P30153|2AAA_HUMAN Serine/threonine protein phosphatase 2... 47 7e-05 sp|P36179|2AAA_DROME Protein phosphatase PP2A, 65 kDa regul... 47 9e-05 sp|Q9UT08|2AAA_SCHPO Protein phosphatase PP2A regulatory su... 46 2e-04 sp|P36875|2AAA_PEA Protein phosphatase PP2A regulatory subu... 42 0.003 sp|P30154|2AAB_HUMAN Serine/threonine protein phosphatase 2... 41 0.006 sp|Q9P1A2|PP4RL_HUMAN Serine/threonine phosphatase 4 regula... 40 0.008 sp|P54613|2AAB_PIG Serine/threonine protein phosphatase 2A,... 39 0.018 sp|Q9VKB9|RBGPR_DROME Rab3 GTPase-activating protein regula... 31 6.4
>sp|Q09543|2AAA_CAEEL Probable protein phosphatase PP2A regulatory subunit (Protein phosphatase PP2A regulatory subunit A) Length = 590 Score = 58.9 bits (141), Expect = 2e-08 Identities = 46/180 (25%), Positives = 84/180 (46%) Frame = +1 Query: 7 DKNWRIRSGVVASLMLIVPLVDEACCRDSLLLTTLSWLRDPVWNIRQGTCEIIGSITGRF 186 D WR+R +V + L+ + + + LL L+WL D V++IR+ + I+ +T +F Sbjct: 416 DGKWRVRLAIVQFMPLLASQLGQEFFDEKLLPLCLNWLTDHVFSIREASTLIMKELTQKF 475 Query: 187 PGLLAEKLVNEKIFKELFEDVNYHFRQCWCFLIEAICKSQPKDCKSDLLTSFLTNHINNL 366 G A + K+ ++L +D NY R F + + ++ ++ + I + Sbjct: 476 GGQWASTNIVPKM-QKLQKDTNYLQRMTCLFCLNTLSEAMTQE--------QILKEIMPI 526 Query: 367 LLQMIEKDPVPNVQISAIRSIKLLSVYLDKTFXXXXXXXXXXXXSTSSSDIDVRDFSDTA 546 + ++E D VPNV+ +A +S+K + L + SD DVR FS+ A Sbjct: 527 VKDLVE-DDVPNVRFNAAKSLKRIGKNLTPSTLTSEVKPLLEKLG-KDSDFDVRYFSEEA 584
>sp|P54612|2AAA_PIG Serine/threonine protein phosphatase 2A, 65 kDa regulatory subunit A, alpha isoform (PP2A, subunit A, PR65-alpha isoform) (PP2A, subunit A, R1-alpha isoform) sp|Q76MZ3|2AAA_MOUSE Serine/threonine protein phosphatase 2A, 65 kDa regulatory subunit A, alpha isoform (PP2A, subunit A, PR65-alpha isoform) (PP2A, subunit A, R1-alpha isoform) Length = 589 Score = 47.4 bits (111), Expect = 7e-05 Identities = 42/181 (23%), Positives = 75/181 (41%) Frame = +1 Query: 7 DKNWRIRSGVVASLMLIVPLVDEACCRDSLLLTTLSWLRDPVWNIRQGTCEIIGSITGRF 186 D WR+R ++ + L+ + + L ++WL D V+ IR+ + + +F Sbjct: 414 DAKWRVRLAIIEYMPLLAGQLGVEFFDEKLNSLCMAWLVDHVYAIREAATSNLKKLVEKF 473 Query: 187 PGLLAEKLVNEKIFKELFEDVNYHFRQCWCFLIEAICKSQPKDCKSDLLTSFLTNHINNL 366 A + K+ + D NY R F I + + C D+ T H+ Sbjct: 474 GKEWAHATIIPKVL-AMSGDPNYLHRMTTLFCINVLSEV----CGQDI----TTKHMLPT 524 Query: 367 LLQMIEKDPVPNVQISAIRSIKLLSVYLDKTFXXXXXXXXXXXXSTSSSDIDVRDFSDTA 546 +L+M DPV NV+ + +S++ + LD + T D+DV+ F+ A Sbjct: 525 VLRM-AGDPVANVRFNVAKSLQKIGPILDNS-TLQSEVKPILEKLTQDQDVDVKYFAQEA 582 Query: 547 L 549 L Sbjct: 583 L 583
>sp|P30153|2AAA_HUMAN Serine/threonine protein phosphatase 2A, 65 kDa regulatory subunit A, alpha isoform (PP2A, subunit A, PR65-alpha isoform) (PP2A, subunit A, R1-alpha isoform) (Medium tumor antigen-associated 61 kDa protein) Length = 589 Score = 47.4 bits (111), Expect = 7e-05 Identities = 42/181 (23%), Positives = 75/181 (41%) Frame = +1 Query: 7 DKNWRIRSGVVASLMLIVPLVDEACCRDSLLLTTLSWLRDPVWNIRQGTCEIIGSITGRF 186 D WR+R ++ + L+ + + L ++WL D V+ IR+ + + +F Sbjct: 414 DAKWRVRLAIIEYMPLLAGQLGVEFFDEKLNSLCMAWLVDHVYAIREAATSNLKKLVEKF 473 Query: 187 PGLLAEKLVNEKIFKELFEDVNYHFRQCWCFLIEAICKSQPKDCKSDLLTSFLTNHINNL 366 A + K+ + D NY R F I + + C D+ T H+ Sbjct: 474 GKEWAHATIIPKVL-AMSGDPNYLHRMTTLFCINVLSEV----CGQDI----TTKHMLPT 524 Query: 367 LLQMIEKDPVPNVQISAIRSIKLLSVYLDKTFXXXXXXXXXXXXSTSSSDIDVRDFSDTA 546 +L+M DPV NV+ + +S++ + LD + T D+DV+ F+ A Sbjct: 525 VLRM-AGDPVANVRFNVAKSLQKIGPILDNS-TLQSEVKPILEKLTQDQDVDVKYFAQEA 582 Query: 547 L 549 L Sbjct: 583 L 583
>sp|P36179|2AAA_DROME Protein phosphatase PP2A, 65 kDa regulatory subunit (Protein phosphatase PP2A regulatory subunit A) (PR65) Length = 591 Score = 47.0 bits (110), Expect = 9e-05 Identities = 37/184 (20%), Positives = 78/184 (42%) Frame = +1 Query: 7 DKNWRIRSGVVASLMLIVPLVDEACCRDSLLLTTLSWLRDPVWNIRQGTCEIIGSITGRF 186 D WR+R ++ + + + + L + WL D V+ IR+ + + +F Sbjct: 416 DSKWRVRLAIIEYMPALAGQLGQEFFDQKLRGLCMGWLNDHVYAIREAATLNMKKLVEQF 475 Query: 187 PGLLAEKLVNEKIFKELFEDVNYHFRQCWCFLIEAICKSQPKDCKSDLLTSFLTNHINNL 366 AE+ + I + + NY R F + + + C +D+ T L + Sbjct: 476 GAPWAEQAIIPMIL-VMSRNKNYLHRMTCLFCLNVLAEV----CGTDITTKLLLPTV--- 527 Query: 367 LLQMIEKDPVPNVQISAIRSIKLLSVYLDKTFXXXXXXXXXXXXSTSSSDIDVRDFSDTA 546 ++ DPV NV+ + ++++ +S +L+ + +T +D+DV+ F+ A Sbjct: 528 --LLLAADPVANVRFNVAKTLQKISPFLEASVIDAQVKPTLDKLNT-DTDVDVKHFAAQA 584 Query: 547 LKDI 558 + I Sbjct: 585 IAGI 588
>sp|Q9UT08|2AAA_SCHPO Protein phosphatase PP2A regulatory subunit A (PR65) (Protein phosphatase 2A 65 kDa regulatory subunit) Length = 590 Score = 45.8 bits (107), Expect = 2e-04 Identities = 43/186 (23%), Positives = 78/186 (41%), Gaps = 4/186 (2%) Frame = +1 Query: 7 DKNWRIRSGVVASLMLIVPLVDEACCRDSLLLTTLSWLRDPVWNIRQGTCEIIGSITGRF 186 DK WR+R ++ + L+ + + + +SWL D V++IR+ + + +T F Sbjct: 412 DKQWRVRLAIIDYIPLLAQQLGVEFFNEKMGNLCMSWLEDHVYSIREAAIKNLRKLTEIF 471 Query: 187 PGLLAEKLVNEKIFKELFEDVNYHFRQCWCFLIEAICKSQPKDCKSDLLTSFLTNHINNL 366 A + + K F + NY +R F I I + L + I Sbjct: 472 GLEWATETIIPK-FLAMRSHPNYLYRMTTIFAISEIAPA--------LNAEVIEKQILPT 522 Query: 367 LLQMIEKDPVPNVQISAIRSIKLLSVYL----DKTFXXXXXXXXXXXXSTSSSDIDVRDF 534 L Q++ DP+PN++ + ++ ++L L D T T +D DV+ F Sbjct: 523 LEQLV-NDPIPNIRFNVAKAFEVLKPVLAAGGDSTVYEQQIIPLLEQL-TKDNDPDVQYF 580 Query: 535 SDTALK 552 + AL+ Sbjct: 581 ATQALE 586
>sp|P36875|2AAA_PEA Protein phosphatase PP2A regulatory subunit A (PR65) Length = 395 Score = 42.0 bits (97), Expect = 0.003 Identities = 40/186 (21%), Positives = 82/186 (44%), Gaps = 4/186 (2%) Frame = +1 Query: 7 DKNWRIRSGVVASLMLIVPLVDEACCRDSLLLTTLSWLRDPVWNIRQGTCEIIGSITGR- 183 D++WR+R ++ + L+ + D L + WL+D ++IR + + Sbjct: 215 DRHWRVRLAIIEYIPLLASQLGVGFFDDKLGALIMQWLKDKEYSIRNAAANNVKRLAAEE 274 Query: 184 -FPGLLAEKLVNEKIFKELFEDVNYHFRQCWCFLIEAICKSQPKDCKSDLLTSFLTNHIN 360 P + ++ + + ++ D +Y +R ++ AI P +L S +T+ Sbjct: 275 FGPEWAMQHIIPQVL--DMINDPHYLYRMT---ILHAISLLAP------VLGSEITS--T 321 Query: 361 NLLLQMI--EKDPVPNVQISAIRSIKLLSVYLDKTFXXXXXXXXXXXXSTSSSDIDVRDF 534 NLL ++ KD VPN++ + + ++ L +D++ S D+DVR F Sbjct: 322 NLLPLVVNASKDRVPNIKFNVAKVLQSLIPIVDESVVESTIRPCLVELS-EDPDVDVRFF 380 Query: 535 SDTALK 552 + AL+ Sbjct: 381 ASQALQ 386
Score = 34.3 bits (77), Expect = 0.58
Identities = 37/145 (25%), Positives = 61/145 (42%), Gaps = 4/145 (2%)
Frame = +1
Query: 7 DKNWRIRSGVVASLMLIVPLVDEACCRDSLLLTTLSWLRDPVWNIRQGTCEIIGSITGRF 186
DK+WR+R V L + V + L+ + LRD V +R G ++ +F
Sbjct: 59 DKSWRVRYMVANQLYELCEAVGPDSTKTELVPAYVRLLRDNVAEVRIAAA---GKVS-KF 114
Query: 187 PGLLAEKLVNEKIF---KELFEDVNYHFRQCWCFLIEAICKSQPKDCK-SDLLTSFLTNH 354
+L+ +L + I KEL D + H R +I + KD LL FL+
Sbjct: 115 SRILSPELAIQHILPCVKELSTDSSQHVRSALASVIMGMAPVLGKDATIEQLLPIFLS-- 172
Query: 355 INNLLLQMIEKDPVPNVQISAIRSI 429
+ KD P+V+++ I +
Sbjct: 173 --------LLKDEFPDVRLNIISKL 189
>sp|P30154|2AAB_HUMAN Serine/threonine protein phosphatase 2A, 65 kDa regulatory subunit A, beta isoform (PP2A, subunit A, PR65-beta isoform) (PP2A, subunit A, R1-beta isoform) Length = 601 Score = 40.8 bits (94), Expect = 0.006 Identities = 39/181 (21%), Positives = 76/181 (41%) Frame = +1 Query: 7 DKNWRIRSGVVASLMLIVPLVDEACCRDSLLLTTLSWLRDPVWNIRQGTCEIIGSITGRF 186 D WR+R ++ + L+ + + L ++WL D V+ IR+ + + +F Sbjct: 426 DAKWRVRLAIIEYMPLLAGQLGVEFFDEKLNSLCMAWLVDHVYAIREAATNNLMKLVQKF 485 Query: 187 PGLLAEKLVNEKIFKELFEDVNYHFRQCWCFLIEAICKSQPKDCKSDLLTSFLTNHINNL 366 A+ + K+ + D NY R F I A+ ++ C ++ T + + Sbjct: 486 GTEWAQNTIVPKVL-VMANDPNYLHRMTTLFCINALSEA----CGQEI----TTKQMLPI 536 Query: 367 LLQMIEKDPVPNVQISAIRSIKLLSVYLDKTFXXXXXXXXXXXXSTSSSDIDVRDFSDTA 546 +L+M D V NV+ + +S++ + LD T D+DV+ F+ A Sbjct: 537 VLKM-AGDQVANVRFNVAKSLQKIGPILD-TNALQGEVKPVLQKLGQDEDMDVKYFAQEA 594 Query: 547 L 549 + Sbjct: 595 I 595
>sp|Q9P1A2|PP4RL_HUMAN Serine/threonine phosphatase 4 regulatory subunit 1-like Length = 438 Score = 40.4 bits (93), Expect = 0.008 Identities = 41/157 (26%), Positives = 72/157 (45%), Gaps = 9/157 (5%) Frame = +1 Query: 4 SDKNWRIRSGVVASLMLIVPLVDEACCRDSLLLTTLSWLRDPVWNIRQGTCEIIGSITGR 183 + +NWR R + L+LI+ L D L+ L D V +R + +++ +I + Sbjct: 242 NSRNWRFRYELAEQLILILELYSPNDVYDYLMHIALKLCADQVSEVRWISFKLVVAILQK 301 Query: 184 F----PGLLAEKLVNEKI--FKELFEDVNYHFRQCWCFLIEAICKSQPKDCKSDLLTSFL 345 F L +NE I F+ + V RQ + F+ +A+ K+C + F+ Sbjct: 302 FYSNSESALGLNFINELIIRFRHCSKWVG---RQAFAFICQAVVS---KECVP--VDQFM 353 Query: 346 TNHINNLLLQMIEKDPVPNVQI---SAIRSIKLLSVY 447 + + +LL + DPVPNV++ A+R + L Y Sbjct: 354 EHLLPSLL--SLASDPVPNVRVLLAKALRQMLLEKAY 388
>sp|P54613|2AAB_PIG Serine/threonine protein phosphatase 2A, 65 kDa regulatory subunit A, beta isoform (PP2A, subunit A, PR65-beta isoform) (PP2A, subunit A, R1-beta isoform) Length = 602 Score = 39.3 bits (90), Expect = 0.018 Identities = 38/181 (20%), Positives = 75/181 (41%) Frame = +1 Query: 7 DKNWRIRSGVVASLMLIVPLVDEACCRDSLLLTTLSWLRDPVWNIRQGTCEIIGSITGRF 186 D WR+R ++ + L+ + + L ++WL D V+ IR+ + + +F Sbjct: 427 DAKWRVRLAIIEYMPLLAGQLGVEFFDEKLNSLCMAWLVDHVYAIREAATNNLMKLVQKF 486 Query: 187 PGLLAEKLVNEKIFKELFEDVNYHFRQCWCFLIEAICKSQPKDCKSDLLTSFLTNHINNL 366 A+ + K+ + D NY R F I + ++ C ++ T + + Sbjct: 487 GTEWAQNTIVPKVL-VMANDPNYLHRMTTLFCINVLSEA----CGQEI----TTKQMLPI 537 Query: 367 LLQMIEKDPVPNVQISAIRSIKLLSVYLDKTFXXXXXXXXXXXXSTSSSDIDVRDFSDTA 546 +L+M D V NV+ + +S++ + LD T D+DV+ F+ A Sbjct: 538 VLKM-AGDQVANVRFNVAKSLQKIGPILD-TDALQEEVKPVLQKLGQDEDMDVKYFAQEA 595 Query: 547 L 549 + Sbjct: 596 I 596
>sp|Q9VKB9|RBGPR_DROME Rab3 GTPase-activating protein regulatory subunit Length = 1341 Score = 30.8 bits (68), Expect = 6.4 Identities = 22/71 (30%), Positives = 35/71 (49%), Gaps = 5/71 (7%) Frame = +1 Query: 22 IRSGVVASLMLIVPLVDEACCRDSL-----LLTTLSWLRDPVWNIRQGTCEIIGSITGRF 186 + SGV+ SLM +V + SL L L+ R P W ++ G C ++ + T +F Sbjct: 962 LESGVLLSLMSWQYMVQWSKQLSSLDHLKAALLCLNQFRTPDWALKHGICCMLWNATLKF 1021 Query: 187 PGLLAEKLVNE 219 P A KL+ + Sbjct: 1022 PLQAAAKLIQK 1032
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 110,789,037
Number of Sequences: 369166
Number of extensions: 2157769
Number of successful extensions: 4718
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 4518
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4715
length of database: 68,354,980
effective HSP length: 111
effective length of database: 47,849,395
effective search space used: 10718264480
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
Cluster detail
