Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= DrC_00504 (882 letters) Database: Non-redundant SwissProt sequences 184,735 sequences; 68,354,980 total letters Score E Sequences producing significant alignments: (bits) Value sp|P02465|CO1A2_BOVIN Collagen alpha 2(I) chain precursor 101 3e-21 sp|O46392|CO1A2_CANFA Collagen alpha 2(I) chain precursor 100 9e-21 sp|O42350|CO1A2_RANCA Collagen alpha 2(I) chain precursor 100 9e-21 sp|Q01149|CO1A2_MOUSE Collagen alpha 2(I) chain precursor 99 2e-20 sp|P02467|CO1A2_CHICK Collagen alpha 2(I) chain precursor 99 2e-20 sp|Q28668|CO1A2_RABIT Collagen alpha 2(I) chain precursor 98 3e-20 sp|O93484|CO1A2_ONCMY Collagen alpha 2(I) chain precursor 97 5e-20 sp|P05997|CO5A2_HUMAN Collagen alpha 2(V) chain precursor 96 2e-19 sp|P28481|CO2A1_MOUSE Collagen alpha 1(II) chain precursor ... 95 2e-19 sp|P02466|CO1A2_RAT Collagen alpha 2(I) chain precursor 94 5e-19
>sp|P02465|CO1A2_BOVIN Collagen alpha 2(I) chain precursor Length = 1364 Score = 101 bits (251), Expect = 3e-21 Identities = 72/221 (32%), Positives = 114/221 (51%), Gaps = 19/221 (8%) Frame = +2 Query: 242 DAILVPDGSKNLPGRTCRHLAEVIPSMLDGLYFIDPNGGTIDDAFEVYCKVNTKQTCIKA 421 + +L P+GS+ P RTCR L P G Y+IDPN G DA +VYC +T +TCI+A Sbjct: 1145 ETLLTPEGSRKNPARTCRDLRLSHPEWSSGYYWIDPNQGCTMDAIKVYCDFSTGETCIRA 1204 Query: 422 KSPTVPSRS-YHSLSSDNYKFLSYLTN-SSRLQYNIE-------RAQLNHLKMHSRFGHQ 574 + +P ++ Y + + + ++ N ++ +YN+E QL +++ + Q Sbjct: 1205 QPEDIPVKNWYRNSKAKKHVWVGETINGGTQFEYNVEGVTTKEMATQLAFMRLLANHASQ 1264 Query: 575 IILFKC-SGIKIISE----TENSVILISDND-KILRYKNSIFSYKVNQDNCYSANG---Y 727 I + C + I + E + +VIL ND +++ NS F+Y V D C Sbjct: 1265 NITYHCKNSIAYMDEETGNLKKAVILQGSNDVELVAEGNSRFTYTVLVDGCSKKTNEWQK 1324 Query: 728 TELEIKT-KSRRMPIRDIGLGDLGSLEQHKIEFSIGDVCFQ 847 T +E KT K R+PI DI D+G +Q +I +IG VCF+ Sbjct: 1325 TIIEYKTNKPSRLPILDIAPLDIGGADQ-EIRLNIGPVCFK 1364
>sp|O46392|CO1A2_CANFA Collagen alpha 2(I) chain precursor Length = 1366 Score = 99.8 bits (247), Expect = 9e-21 Identities = 71/221 (32%), Positives = 112/221 (50%), Gaps = 19/221 (8%) Frame = +2 Query: 242 DAILVPDGSKNLPGRTCRHLAEVIPSMLDGLYFIDPNGGTIDDAFEVYCKVNTKQTCIKA 421 + +L P+GS+ P RTCR L P G Y+IDPN G DA +VYC +T +TCI+A Sbjct: 1147 ETLLTPEGSRKNPARTCRDLRLSHPEWSSGYYWIDPNQGCTMDAIKVYCDFSTGETCIRA 1206 Query: 422 KSPTVPSRS-YHSLSSDNYKFLSYLTN-SSRLQYNIE-------RAQLNHLKMHSRFGHQ 574 + +P+++ Y + + +L N ++ +YN+E QL +++ + Q Sbjct: 1207 QPENIPAKNWYRNSKVKKHIWLGETINGGTQFEYNVEGVTTKEMATQLAFMRLLANHASQ 1266 Query: 575 IILFKC-SGIKIISE----TENSVILISDND-KILRYKNSIFSYKVNQDNCYSANG---Y 727 I + C + I + E + +VIL ND +++ NS F+Y V D C Sbjct: 1267 NITYHCKNSIAYMDEETGNLKKAVILQGSNDVELVAEGNSRFTYTVLVDGCSKKTNEWRK 1326 Query: 728 TELEIKT-KSRRMPIRDIGLGDLGSLEQHKIEFSIGDVCFQ 847 T +E KT K R+PI DI D+G +Q + +G VCF+ Sbjct: 1327 TIIEYKTNKPSRLPILDIAPLDIGDADQ-EFRVDVGPVCFK 1366
>sp|O42350|CO1A2_RANCA Collagen alpha 2(I) chain precursor Length = 1355 Score = 99.8 bits (247), Expect = 9e-21 Identities = 73/223 (32%), Positives = 112/223 (50%), Gaps = 21/223 (9%) Frame = +2 Query: 242 DAILVPDGSKNLPGRTCRHLAEVIPSMLDGLYFIDPNGGTIDDAFEVYCKVNTKQTCIKA 421 + IL P+GS+ P RTCR L P G Y+IDPN G DA V+C ++ +TCI A Sbjct: 1134 EVILTPEGSRKNPARTCRDLRLSHPEWTSGFYWIDPNQGCTSDAIRVFCDFSSGETCIHA 1193 Query: 422 KSPTVPSRSYHSLSSDNYK----FLSYLTNSSRLQYNIE-------RAQLNHLKMHSRFG 568 + ++++ +S+ K F L ++ +Y+ E QL +++ + Sbjct: 1194 NPDEITQKNWYINTSNKDKKHLWFGEILNGGTQFEYHDEGLTAKDMATQLAFMRLLANQA 1253 Query: 569 HQIILFKC-SGIKIISE----TENSVILISDNDKILRYK-NSIFSYKVNQDNCYSAN--- 721 Q I + C + I + E + +VIL ND LR + N+ F+Y V +D C Sbjct: 1254 SQNITYHCKNSIAYMDEETGNLKKAVILQGSNDVELRAEGNTRFTYSVLEDGCTKHTGEW 1313 Query: 722 GYTELEIKT-KSRRMPIRDIGLGDLGSLEQHKIEFSIGDVCFQ 847 G T +E +T K R+PI DI D+G +Q +I F IG VCF+ Sbjct: 1314 GKTVIEYRTNKPSRLPILDIAPLDIGGHDQ-EIGFEIGPVCFK 1355
>sp|Q01149|CO1A2_MOUSE Collagen alpha 2(I) chain precursor Length = 1372 Score = 99.0 bits (245), Expect = 2e-20 Identities = 72/221 (32%), Positives = 110/221 (49%), Gaps = 19/221 (8%) Frame = +2 Query: 242 DAILVPDGSKNLPGRTCRHLAEVIPSMLDGLYFIDPNGGTIDDAFEVYCKVNTKQTCIKA 421 + +L P+GS+ P RTCR L P Y+IDPN G DA +VYC +T +TCI+A Sbjct: 1153 ETLLTPEGSRKNPARTCRDLRLSHPEWNSDYYWIDPNQGCTMDAIKVYCDFSTGETCIQA 1212 Query: 422 KSPTVPSR-SYHSLSSDNYKFLSYLTN-SSRLQYNIE-------RAQLNHLKMHSRFGHQ 574 + P++ SY ++ + +L N S+ +YN+E QL +++ + Q Sbjct: 1213 QPVNTPAKNSYSRAQANKHVWLGETINGGSQFEYNVEGVSSKEMATQLAFMRLLANRASQ 1272 Query: 575 IILFKC-SGIKIISETENS----VILISDND-KILRYKNSIFSYKVNQDNCYSAN---GY 727 I + C + I + E S V+L ND +++ NS F+Y V D C G Sbjct: 1273 NITYHCKNSIAYLDEETGSLNKAVLLQGSNDVELVAEGNSRFTYSVLVDGCSKKTNEWGK 1332 Query: 728 TELEIKT-KSRRMPIRDIGLGDLGSLEQHKIEFSIGDVCFQ 847 T +E KT K R+P DI D+G +Q + +G VCF+ Sbjct: 1333 TIIEYKTNKPSRLPFLDIAPLDIGGADQ-EFRVEVGPVCFK 1372
>sp|P02467|CO1A2_CHICK Collagen alpha 2(I) chain precursor Length = 1362 Score = 98.6 bits (244), Expect = 2e-20 Identities = 73/223 (32%), Positives = 108/223 (48%), Gaps = 21/223 (9%) Frame = +2 Query: 242 DAILVPDGSKNLPGRTCRHLAEVIPSMLDGLYFIDPNGGTIDDAFEVYCKVNTKQTCIKA 421 + +L P+GSK P RTCR L P G Y+IDPN G DA YC T +TCI A Sbjct: 1141 ETLLTPEGSKKNPARTCRDLRLSHPEWSSGFYWIDPNQGCTADAIRAYCDFATGETCIHA 1200 Query: 422 KSPTVPSRSYHSLSSDNYK----FLSYLTNSSRLQYNIE-------RAQLNHLKMHSRFG 568 +P+++++ + K F + ++ +YN E QL +++ + Sbjct: 1201 SLEDIPTKTWYVSKNPKDKKHIWFGETINGGTQFEYNGEGVTTKDMATQLAFMRLLANHA 1260 Query: 569 HQIILFKC-SGIKIISE----TENSVILISDNDKILRYK-NSIFSYKVNQDNCYSAN--- 721 Q I + C + I + E + +VIL ND LR + NS F++ V D C N Sbjct: 1261 SQNITYHCKNSIAYMDEETGNLKKAVILQGSNDVELRAEGNSRFTFSVLVDGCSKKNNKW 1320 Query: 722 GYTELEIKT-KSRRMPIRDIGLGDLGSLEQHKIEFSIGDVCFQ 847 G T +E +T K R+PI DI D+G +Q + IG VCF+ Sbjct: 1321 GKTIIEYRTNKPSRLPILDIAPLDIGGADQ-EFGLHIGPVCFK 1362
>sp|Q28668|CO1A2_RABIT Collagen alpha 2(I) chain precursor Length = 526 Score = 97.8 bits (242), Expect = 3e-20 Identities = 70/221 (31%), Positives = 108/221 (48%), Gaps = 19/221 (8%) Frame = +2 Query: 242 DAILVPDGSKNLPGRTCRHLAEVIPSMLDGLYFIDPNGGTIDDAFEVYCKVNTKQTCIKA 421 + +L P+GS+ P RTCR L P G Y+IDPN G DA +VYC +T +TCI+A Sbjct: 307 ETLLTPEGSRKNPARTCRDLRLSHPEWSSGYYWIDPNQGCTMDAIKVYCDFSTGETCIRA 366 Query: 422 KSPTVPSRS-YHSLSSDNYKFLSYLTN-SSRLQYNIE-------RAQLNHLKMHSRFGHQ 574 + + ++ Y S + + +L N ++ +YN+E QL +++ + Q Sbjct: 367 QPENISVKNWYKSSKAKKHVWLGETINGGTQFEYNVEGVTSKEMATQLAFMRLLANHASQ 426 Query: 575 IILFKCSGIKIISETE-----NSVILISDND-KILRYKNSIFSYKVNQDNCYSAN---GY 727 I + C + E +VIL ND +++ NS F+Y V D C G Sbjct: 427 NITYHCKNSIAYMDEETGNLNKAVILQGSNDVELVAEGNSRFTYTVLVDGCTKKTNEWGK 486 Query: 728 TELEIKT-KSRRMPIRDIGLGDLGSLEQHKIEFSIGDVCFQ 847 T +E KT K R+P DI D+G +Q + +G VCF+ Sbjct: 487 TIIEYKTNKPSRLPFLDIAPLDIGGADQ-EFYVDVGPVCFK 526
>sp|O93484|CO1A2_ONCMY Collagen alpha 2(I) chain precursor Length = 1356 Score = 97.4 bits (241), Expect = 5e-20 Identities = 73/226 (32%), Positives = 108/226 (47%), Gaps = 20/226 (8%) Frame = +2 Query: 230 NFGADAILVPDGSKNLPGRTCRHLAEVIPSMLDGLYFIDPNGGTIDDAFEVYCKVNTKQT 409 N + +L P+GSK P RTCR + P G Y+IDPN G I DA + YC +T T Sbjct: 1133 NSQIENLLTPEGSKKNPARTCRDIRLSHPDWSSGFYWIDPNQGCIADAIKAYCDFSTGHT 1192 Query: 410 CIKAKSPTVPSRSYHSLSSDNYK---FLSYLTNSSRLQYNIE-------RAQLNHLKMHS 559 CI ++ ++++ SS+N K F + + YN E QL +++ + Sbjct: 1193 CIHPHPESIARKNWYR-SSENKKHVWFGETINGGTEFAYNDETLSPQSMATQLAFMRLLA 1251 Query: 560 RFGHQIILFKCSGIKIISETEN-----SVILISDNDKILRYK-NSIFSYKVNQDNCYSAN 721 Q I + C + EN +V+L ND LR + NS F++ V +D C Sbjct: 1252 NQATQNITYHCKNSVAYMDGENGNLKKAVLLQGSNDVELRAEGNSRFTFNVLEDGCTRHT 1311 Query: 722 GY---TELEIKT-KSRRMPIRDIGLGDLGSLEQHKIEFSIGDVCFQ 847 G T +E +T K R+PI DI D+G +Q + IG VCF+ Sbjct: 1312 GQWSKTVIEYRTNKPSRLPILDIAPLDIGEADQ-EFGLDIGPVCFK 1356
>sp|P05997|CO5A2_HUMAN Collagen alpha 2(V) chain precursor Length = 1496 Score = 95.5 bits (236), Expect = 2e-19 Identities = 69/215 (32%), Positives = 106/215 (49%), Gaps = 19/215 (8%) Frame = +2 Query: 257 PDGSKNLPGRTCRHLAEVIPSMLDGLYFIDPNGGTIDDAFEVYCKVNTKQTCIKAKSPTV 436 PDGSK P RTC L + G Y+IDPN G+++DA +VYC + T +TCI A +V Sbjct: 1282 PDGSKKHPARTCDDLKLCHSAKQSGEYWIDPNQGSVEDAIKVYCNMETGETCISANPSSV 1341 Query: 437 PSRSYHSLSSDNYKFLSY---LTNSSRLQY------NIERAQLNHLKMHSRFGHQIILFK 589 P +++ + S + K + Y + S+ Y N Q+ L++ S+ Q I + Sbjct: 1342 PRKTWWASKSPDNKPVWYGLDMNRGSQFAYGDHQSPNTAITQMTFLRLLSKEASQNITYI 1401 Query: 590 CSGI-----KIISETENSVILISDNDKILRYKNSI-FSYKVNQDNCYSAN---GYTELEI 742 C + +V+L ND ++ + +I F Y V QD C N G T E Sbjct: 1402 CKNSVGYMDDQAKNLKKAVVLKGANDLDIKAEGNIRFRYIVLQDTCSKRNGNVGKTVFEY 1461 Query: 743 KTKS-RRMPIRDIGLGDLGSLEQHKIEFSIGDVCF 844 +T++ R+PI D+ D+G +Q + IG VCF Sbjct: 1462 RTQNVARLPIIDLAPVDVGGTDQ-EFGVEIGPVCF 1495
>sp|P28481|CO2A1_MOUSE Collagen alpha 1(II) chain precursor [Contains: Chondrocalcin] Length = 1459 Score = 95.1 bits (235), Expect = 2e-19 Identities = 69/221 (31%), Positives = 106/221 (47%), Gaps = 20/221 (9%) Frame = +2 Query: 242 DAILVPDGSKNLPGRTCRHLAEVIPSMLDGLYFIDPNGGTIDDAFEVYCKVNTKQTCIKA 421 ++I PDGS+ P RTC+ L P G Y+IDPN G DA +V+C + T +TC+ Sbjct: 1239 ESIRSPDGSRKNPARTCQDLKLCHPEWKSGDYWIDPNQGCTLDAMKVFCNMETGETCVYP 1298 Query: 422 KSPTVPSRSYHSLSSDNYKFL----------SYLTNSSRLQYNIERAQLNHLKMHSRFGH 571 TVP +++ S S K + + L N Q+ L++ S G Sbjct: 1299 NPATVPRKNWWSSKSKEKKHIWFGETMNGGFHFSYGDGNLAPNTANVQMTFLRLLSTEGS 1358 Query: 572 QIILFKC-SGIKIISET----ENSVILISDNDKILRYK-NSIFSYKVNQDNCYSAN---G 724 Q I + C + I + E + ++++ ND +R + NS F+Y +D C G Sbjct: 1359 QNITYHCKNSIAYLDEAAGNLKKALLIQGSNDVEMRAEGNSRFTYTALKDGCTKHTGKWG 1418 Query: 725 YTELEIKT-KSRRMPIRDIGLGDLGSLEQHKIEFSIGDVCF 844 T +E ++ K+ R+PI DI D+G EQ + IG VCF Sbjct: 1419 KTVIEYRSQKTSRLPIIDIAPMDIGGAEQ-EFGVDIGPVCF 1458
>sp|P02466|CO1A2_RAT Collagen alpha 2(I) chain precursor Length = 1372 Score = 94.0 bits (232), Expect = 5e-19 Identities = 71/221 (32%), Positives = 108/221 (48%), Gaps = 19/221 (8%) Frame = +2 Query: 242 DAILVPDGSKNLPGRTCRHLAEVIPSMLDGLYFIDPNGGTIDDAFEVYCKVNTKQTCIKA 421 + +L P+GS+ P RTCR L P Y+IDPN G DA +VYC +T +TCI+A Sbjct: 1153 ETLLTPEGSRKNPARTCRDLRLSHPEWKSDYYWIDPNQGCTMDAIKVYCDFSTGETCIQA 1212 Query: 422 KSPTVPSRSYHSLSSDN-YKFLSYLTN-SSRLQYNIE-------RAQLNHLKMHSRFGHQ 574 + P+++ +S + N + +L N S+ +YN E QL +++ + Q Sbjct: 1213 QPVNTPAKNAYSRAQANKHVWLGETINGGSQFEYNAEGVSSKEMATQLAFMRLLANRASQ 1272 Query: 575 IILFKC-SGIKIISE----TENSVILISDND-KILRYKNSIFSYKVNQDNCYSANG---Y 727 I + C + I + E +VIL ND +++ NS F+Y V D C Sbjct: 1273 NITYHCKNSIAYLDEETGRLNKAVILQGSNDVELVAEGNSRFTYTVLVDGCSKKTNEWDK 1332 Query: 728 TELEIKT-KSRRMPIRDIGLGDLGSLEQHKIEFSIGDVCFQ 847 T +E KT K R+P DI D+G Q + +G VCF+ Sbjct: 1333 TVIEYKTNKPSRLPFLDIAPLDIGGTNQ-EFRVEVGPVCFK 1372
Database: Non-redundant SwissProt sequences Posted date: Dec 6, 2005 7:40 AM Number of letters in database: 68,354,980 Number of sequences in database: 184,735 Database: swissprot.01 Posted date: Dec 6, 2005 8:18 AM Number of letters in database: 66,202,850 Number of sequences in database: 184,431 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 91,665,792 Number of Sequences: 369166 Number of extensions: 1813607 Number of successful extensions: 5589 Number of sequences better than 10.0: 10 Number of HSP's better than 10.0 without gapping: 5330 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 5562 length of database: 68,354,980 effective HSP length: 110 effective length of database: 48,034,130 effective search space used: 8790245790 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)