Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_013_E24
(777 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|O46392|CO1A2_CANFA Collagen alpha 2(I) chain precursor 87 5e-17
sp|Q01149|CO1A2_MOUSE Collagen alpha 2(I) chain precursor 86 9e-17
sp|P02467|CO1A2_CHICK Collagen alpha 2(I) chain precursor 86 9e-17
sp|P02465|CO1A2_BOVIN Collagen alpha 2(I) chain precursor 86 1e-16
sp|Q28668|CO1A2_RABIT Collagen alpha 2(I) chain precursor 86 1e-16
sp|O93484|CO1A2_ONCMY Collagen alpha 2(I) chain precursor 85 3e-16
sp|P05997|CO5A2_HUMAN Collagen alpha 2(V) chain precursor 84 3e-16
sp|O42350|CO1A2_RANCA Collagen alpha 2(I) chain precursor 84 4e-16
sp|P02466|CO1A2_RAT Collagen alpha 2(I) chain precursor 82 2e-15
sp|P28481|CO2A1_MOUSE Collagen alpha 1(II) chain precursor ... 82 2e-15
>sp|O46392|CO1A2_CANFA Collagen alpha 2(I) chain precursor
Length = 1366
Score = 87.0 bits (214), Expect = 5e-17
Identities = 63/197 (31%), Positives = 99/197 (50%), Gaps = 19/197 (9%)
Frame = +2
Query: 242 DAILVPDGSKNLPGRTCRHLAEVIPSMLDGLYFIDPNGGTIDDAFEVYCKVNTKQTCIKA 421
+ +L P+GS+ P RTCR L P G Y+IDPN G DA +VYC +T +TCI+A
Sbjct: 1147 ETLLTPEGSRKNPARTCRDLRLSHPEWSSGYYWIDPNQGCTMDAIKVYCDFSTGETCIRA 1206
Query: 422 KSPTVPSRS-YHSLSSDNYKFLSYLTN-SSRLQYNIE-------RAQLNHLKMHSRFGHQ 574
+ +P+++ Y + + +L N ++ +YN+E QL +++ + Q
Sbjct: 1207 QPENIPAKNWYRNSKVKKHIWLGETINGGTQFEYNVEGVTTKEMATQLAFMRLLANHASQ 1266
Query: 575 IILFKC-SGIKIISE----TENSVILISDND-KILRYKNSIFSYKVNQDNCYSANG---Y 727
I + C + I + E + +VIL ND +++ NS F+Y V D C
Sbjct: 1267 NITYHCKNSIAYMDEETGNLKKAVILQGSNDVELVAEGNSRFTYTVLVDGCSKKTNEWRK 1326
Query: 728 TELEIKT-KSRRMPIRD 775
T +E KT K R+PI D
Sbjct: 1327 TIIEYKTNKPSRLPILD 1343
>sp|Q01149|CO1A2_MOUSE Collagen alpha 2(I) chain precursor
Length = 1372
Score = 86.3 bits (212), Expect = 9e-17
Identities = 64/197 (32%), Positives = 97/197 (49%), Gaps = 19/197 (9%)
Frame = +2
Query: 242 DAILVPDGSKNLPGRTCRHLAEVIPSMLDGLYFIDPNGGTIDDAFEVYCKVNTKQTCIKA 421
+ +L P+GS+ P RTCR L P Y+IDPN G DA +VYC +T +TCI+A
Sbjct: 1153 ETLLTPEGSRKNPARTCRDLRLSHPEWNSDYYWIDPNQGCTMDAIKVYCDFSTGETCIQA 1212
Query: 422 KSPTVPSR-SYHSLSSDNYKFLSYLTN-SSRLQYNIE-------RAQLNHLKMHSRFGHQ 574
+ P++ SY ++ + +L N S+ +YN+E QL +++ + Q
Sbjct: 1213 QPVNTPAKNSYSRAQANKHVWLGETINGGSQFEYNVEGVSSKEMATQLAFMRLLANRASQ 1272
Query: 575 IILFKC-SGIKIISETENS----VILISDND-KILRYKNSIFSYKVNQDNCYSAN---GY 727
I + C + I + E S V+L ND +++ NS F+Y V D C G
Sbjct: 1273 NITYHCKNSIAYLDEETGSLNKAVLLQGSNDVELVAEGNSRFTYSVLVDGCSKKTNEWGK 1332
Query: 728 TELEIKT-KSRRMPIRD 775
T +E KT K R+P D
Sbjct: 1333 TIIEYKTNKPSRLPFLD 1349
>sp|P02467|CO1A2_CHICK Collagen alpha 2(I) chain precursor
Length = 1362
Score = 86.3 bits (212), Expect = 9e-17
Identities = 64/199 (32%), Positives = 95/199 (47%), Gaps = 21/199 (10%)
Frame = +2
Query: 242 DAILVPDGSKNLPGRTCRHLAEVIPSMLDGLYFIDPNGGTIDDAFEVYCKVNTKQTCIKA 421
+ +L P+GSK P RTCR L P G Y+IDPN G DA YC T +TCI A
Sbjct: 1141 ETLLTPEGSKKNPARTCRDLRLSHPEWSSGFYWIDPNQGCTADAIRAYCDFATGETCIHA 1200
Query: 422 KSPTVPSRSYHSLSSDNYK----FLSYLTNSSRLQYNIE-------RAQLNHLKMHSRFG 568
+P+++++ + K F + ++ +YN E QL +++ +
Sbjct: 1201 SLEDIPTKTWYVSKNPKDKKHIWFGETINGGTQFEYNGEGVTTKDMATQLAFMRLLANHA 1260
Query: 569 HQIILFKC-SGIKIISE----TENSVILISDNDKILRYK-NSIFSYKVNQDNCYSAN--- 721
Q I + C + I + E + +VIL ND LR + NS F++ V D C N
Sbjct: 1261 SQNITYHCKNSIAYMDEETGNLKKAVILQGSNDVELRAEGNSRFTFSVLVDGCSKKNNKW 1320
Query: 722 GYTELEIKT-KSRRMPIRD 775
G T +E +T K R+PI D
Sbjct: 1321 GKTIIEYRTNKPSRLPILD 1339
>sp|P02465|CO1A2_BOVIN Collagen alpha 2(I) chain precursor
Length = 1364
Score = 85.9 bits (211), Expect = 1e-16
Identities = 62/197 (31%), Positives = 99/197 (50%), Gaps = 19/197 (9%)
Frame = +2
Query: 242 DAILVPDGSKNLPGRTCRHLAEVIPSMLDGLYFIDPNGGTIDDAFEVYCKVNTKQTCIKA 421
+ +L P+GS+ P RTCR L P G Y+IDPN G DA +VYC +T +TCI+A
Sbjct: 1145 ETLLTPEGSRKNPARTCRDLRLSHPEWSSGYYWIDPNQGCTMDAIKVYCDFSTGETCIRA 1204
Query: 422 KSPTVPSRS-YHSLSSDNYKFLSYLTN-SSRLQYNIE-------RAQLNHLKMHSRFGHQ 574
+ +P ++ Y + + + ++ N ++ +YN+E QL +++ + Q
Sbjct: 1205 QPEDIPVKNWYRNSKAKKHVWVGETINGGTQFEYNVEGVTTKEMATQLAFMRLLANHASQ 1264
Query: 575 IILFKC-SGIKIISE----TENSVILISDND-KILRYKNSIFSYKVNQDNCYSANG---Y 727
I + C + I + E + +VIL ND +++ NS F+Y V D C
Sbjct: 1265 NITYHCKNSIAYMDEETGNLKKAVILQGSNDVELVAEGNSRFTYTVLVDGCSKKTNEWQK 1324
Query: 728 TELEIKT-KSRRMPIRD 775
T +E KT K R+PI D
Sbjct: 1325 TIIEYKTNKPSRLPILD 1341
>sp|Q28668|CO1A2_RABIT Collagen alpha 2(I) chain precursor
Length = 526
Score = 85.9 bits (211), Expect = 1e-16
Identities = 62/197 (31%), Positives = 95/197 (48%), Gaps = 19/197 (9%)
Frame = +2
Query: 242 DAILVPDGSKNLPGRTCRHLAEVIPSMLDGLYFIDPNGGTIDDAFEVYCKVNTKQTCIKA 421
+ +L P+GS+ P RTCR L P G Y+IDPN G DA +VYC +T +TCI+A
Sbjct: 307 ETLLTPEGSRKNPARTCRDLRLSHPEWSSGYYWIDPNQGCTMDAIKVYCDFSTGETCIRA 366
Query: 422 KSPTVPSRS-YHSLSSDNYKFLSYLTN-SSRLQYNIE-------RAQLNHLKMHSRFGHQ 574
+ + ++ Y S + + +L N ++ +YN+E QL +++ + Q
Sbjct: 367 QPENISVKNWYKSSKAKKHVWLGETINGGTQFEYNVEGVTSKEMATQLAFMRLLANHASQ 426
Query: 575 IILFKCSGIKIISETE-----NSVILISDND-KILRYKNSIFSYKVNQDNCYSAN---GY 727
I + C + E +VIL ND +++ NS F+Y V D C G
Sbjct: 427 NITYHCKNSIAYMDEETGNLNKAVILQGSNDVELVAEGNSRFTYTVLVDGCTKKTNEWGK 486
Query: 728 TELEIKT-KSRRMPIRD 775
T +E KT K R+P D
Sbjct: 487 TIIEYKTNKPSRLPFLD 503
>sp|O93484|CO1A2_ONCMY Collagen alpha 2(I) chain precursor
Length = 1356
Score = 84.7 bits (208), Expect = 3e-16
Identities = 64/202 (31%), Positives = 95/202 (47%), Gaps = 20/202 (9%)
Frame = +2
Query: 230 NFGADAILVPDGSKNLPGRTCRHLAEVIPSMLDGLYFIDPNGGTIDDAFEVYCKVNTKQT 409
N + +L P+GSK P RTCR + P G Y+IDPN G I DA + YC +T T
Sbjct: 1133 NSQIENLLTPEGSKKNPARTCRDIRLSHPDWSSGFYWIDPNQGCIADAIKAYCDFSTGHT 1192
Query: 410 CIKAKSPTVPSRSYHSLSSDNYK---FLSYLTNSSRLQYNIE-------RAQLNHLKMHS 559
CI ++ ++++ SS+N K F + + YN E QL +++ +
Sbjct: 1193 CIHPHPESIARKNWYR-SSENKKHVWFGETINGGTEFAYNDETLSPQSMATQLAFMRLLA 1251
Query: 560 RFGHQIILFKCSGIKIISETEN-----SVILISDNDKILRYK-NSIFSYKVNQDNCYSAN 721
Q I + C + EN +V+L ND LR + NS F++ V +D C
Sbjct: 1252 NQATQNITYHCKNSVAYMDGENGNLKKAVLLQGSNDVELRAEGNSRFTFNVLEDGCTRHT 1311
Query: 722 GY---TELEIKT-KSRRMPIRD 775
G T +E +T K R+PI D
Sbjct: 1312 GQWSKTVIEYRTNKPSRLPILD 1333
>sp|P05997|CO5A2_HUMAN Collagen alpha 2(V) chain precursor
Length = 1496
Score = 84.3 bits (207), Expect = 3e-16
Identities = 61/192 (31%), Positives = 94/192 (48%), Gaps = 19/192 (9%)
Frame = +2
Query: 257 PDGSKNLPGRTCRHLAEVIPSMLDGLYFIDPNGGTIDDAFEVYCKVNTKQTCIKAKSPTV 436
PDGSK P RTC L + G Y+IDPN G+++DA +VYC + T +TCI A +V
Sbjct: 1282 PDGSKKHPARTCDDLKLCHSAKQSGEYWIDPNQGSVEDAIKVYCNMETGETCISANPSSV 1341
Query: 437 PSRSYHSLSSDNYKFLSY---LTNSSRLQY------NIERAQLNHLKMHSRFGHQIILFK 589
P +++ + S + K + Y + S+ Y N Q+ L++ S+ Q I +
Sbjct: 1342 PRKTWWASKSPDNKPVWYGLDMNRGSQFAYGDHQSPNTAITQMTFLRLLSKEASQNITYI 1401
Query: 590 CSGI-----KIISETENSVILISDNDKILRYKNSI-FSYKVNQDNCYSAN---GYTELEI 742
C + +V+L ND ++ + +I F Y V QD C N G T E
Sbjct: 1402 CKNSVGYMDDQAKNLKKAVVLKGANDLDIKAEGNIRFRYIVLQDTCSKRNGNVGKTVFEY 1461
Query: 743 KTKS-RRMPIRD 775
+T++ R+PI D
Sbjct: 1462 RTQNVARLPIID 1473
>sp|O42350|CO1A2_RANCA Collagen alpha 2(I) chain precursor
Length = 1355
Score = 84.0 bits (206), Expect = 4e-16
Identities = 62/199 (31%), Positives = 97/199 (48%), Gaps = 21/199 (10%)
Frame = +2
Query: 242 DAILVPDGSKNLPGRTCRHLAEVIPSMLDGLYFIDPNGGTIDDAFEVYCKVNTKQTCIKA 421
+ IL P+GS+ P RTCR L P G Y+IDPN G DA V+C ++ +TCI A
Sbjct: 1134 EVILTPEGSRKNPARTCRDLRLSHPEWTSGFYWIDPNQGCTSDAIRVFCDFSSGETCIHA 1193
Query: 422 KSPTVPSRSYHSLSSDNYK----FLSYLTNSSRLQYNIE-------RAQLNHLKMHSRFG 568
+ ++++ +S+ K F L ++ +Y+ E QL +++ +
Sbjct: 1194 NPDEITQKNWYINTSNKDKKHLWFGEILNGGTQFEYHDEGLTAKDMATQLAFMRLLANQA 1253
Query: 569 HQIILFKC-SGIKIISE----TENSVILISDNDKILRYK-NSIFSYKVNQDNCYSAN--- 721
Q I + C + I + E + +VIL ND LR + N+ F+Y V +D C
Sbjct: 1254 SQNITYHCKNSIAYMDEETGNLKKAVILQGSNDVELRAEGNTRFTYSVLEDGCTKHTGEW 1313
Query: 722 GYTELEIKT-KSRRMPIRD 775
G T +E +T K R+PI D
Sbjct: 1314 GKTVIEYRTNKPSRLPILD 1332
>sp|P02466|CO1A2_RAT Collagen alpha 2(I) chain precursor
Length = 1372
Score = 82.0 bits (201), Expect = 2e-15
Identities = 63/197 (31%), Positives = 96/197 (48%), Gaps = 19/197 (9%)
Frame = +2
Query: 242 DAILVPDGSKNLPGRTCRHLAEVIPSMLDGLYFIDPNGGTIDDAFEVYCKVNTKQTCIKA 421
+ +L P+GS+ P RTCR L P Y+IDPN G DA +VYC +T +TCI+A
Sbjct: 1153 ETLLTPEGSRKNPARTCRDLRLSHPEWKSDYYWIDPNQGCTMDAIKVYCDFSTGETCIQA 1212
Query: 422 KSPTVPSRSYHSLSSDN-YKFLSYLTN-SSRLQYNIE-------RAQLNHLKMHSRFGHQ 574
+ P+++ +S + N + +L N S+ +YN E QL +++ + Q
Sbjct: 1213 QPVNTPAKNAYSRAQANKHVWLGETINGGSQFEYNAEGVSSKEMATQLAFMRLLANRASQ 1272
Query: 575 IILFKC-SGIKIISE----TENSVILISDND-KILRYKNSIFSYKVNQDNCYSANG---Y 727
I + C + I + E +VIL ND +++ NS F+Y V D C
Sbjct: 1273 NITYHCKNSIAYLDEETGRLNKAVILQGSNDVELVAEGNSRFTYTVLVDGCSKKTNEWDK 1332
Query: 728 TELEIKT-KSRRMPIRD 775
T +E KT K R+P D
Sbjct: 1333 TVIEYKTNKPSRLPFLD 1349
>sp|P28481|CO2A1_MOUSE Collagen alpha 1(II) chain precursor [Contains: Chondrocalcin]
Length = 1459
Score = 81.6 bits (200), Expect = 2e-15
Identities = 59/198 (29%), Positives = 94/198 (47%), Gaps = 20/198 (10%)
Frame = +2
Query: 242 DAILVPDGSKNLPGRTCRHLAEVIPSMLDGLYFIDPNGGTIDDAFEVYCKVNTKQTCIKA 421
++I PDGS+ P RTC+ L P G Y+IDPN G DA +V+C + T +TC+
Sbjct: 1239 ESIRSPDGSRKNPARTCQDLKLCHPEWKSGDYWIDPNQGCTLDAMKVFCNMETGETCVYP 1298
Query: 422 KSPTVPSRSYHSLSSDNYKFL----------SYLTNSSRLQYNIERAQLNHLKMHSRFGH 571
TVP +++ S S K + + L N Q+ L++ S G
Sbjct: 1299 NPATVPRKNWWSSKSKEKKHIWFGETMNGGFHFSYGDGNLAPNTANVQMTFLRLLSTEGS 1358
Query: 572 QIILFKC-SGIKIISET----ENSVILISDNDKILRYK-NSIFSYKVNQDNCYSAN---G 724
Q I + C + I + E + ++++ ND +R + NS F+Y +D C G
Sbjct: 1359 QNITYHCKNSIAYLDEAAGNLKKALLIQGSNDVEMRAEGNSRFTYTALKDGCTKHTGKWG 1418
Query: 725 YTELEIKT-KSRRMPIRD 775
T +E ++ K+ R+PI D
Sbjct: 1419 KTVIEYRSQKTSRLPIID 1436
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 78,148,161
Number of Sequences: 369166
Number of extensions: 1492427
Number of successful extensions: 4933
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 4731
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4920
length of database: 68,354,980
effective HSP length: 108
effective length of database: 48,403,600
effective search space used: 7260540000
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)