DrC_00462
- Cluster detail
- GO Category :
- Consensus Sequence :
BLASTX 2.2.13 [Nov-27-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= DrC_00462 (1481 letters) Database: Non-redundant SwissProt sequences 184,735 sequences; 68,354,980 total letters Score E Sequences producing significant alignments: (bits) Value sp|P30038|AL4A1_HUMAN Delta-1-pyrroline-5-carboxylate dehyd... 565 e-160 sp|Q8CHT0|AL4A1_MOUSE Delta-1-pyrroline-5-carboxylate dehyd... 559 e-159 sp|O74766|PUT2_SCHPO Probable delta-1-pyrroline-5-carboxyla... 442 e-123 sp|Q9P8I0|PUT2_EMENI Delta-1-pyrroline-5-carboxylate dehydr... 421 e-117 sp|P78568|PUT2_AGABI Delta-1-pyrroline-5-carboxylate dehydr... 411 e-114 sp|P07275|PUT2_YEAST Delta-1-pyrroline-5-carboxylate dehydr... 403 e-112 sp|Q8ERF4|ROCA_OCEIH 1-pyrroline-5-carboxylate dehydrogenas... 242 2e-63 sp|P39634|ROCA_BACSU 1-pyrroline-5-carboxylate dehydrogenas... 238 3e-62 sp|Q4L966|ROCA_STAHJ 1-pyrroline-5-carboxylate dehydrogenas... 237 7e-62 sp|Q9K9B2|ROCA1_BACHD 1-pyrroline-5-carboxylate dehydrogena... 236 2e-61
>sp|P30038|AL4A1_HUMAN Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial precursor (P5C dehydrogenase) (Aldehyde dehydrogenase 4A1) Length = 563 Score = 565 bits (1456), Expect = e-160 Identities = 268/474 (56%), Positives = 359/474 (75%), Gaps = 1/474 (0%) Frame = +1 Query: 4 PFDHKKNLAQFYFADEKIINKAIKSCLEAREKWDKTPLKDRAQIFLKAADLMSKTYRPHL 183 PF+H +A+F +AD+ ++NKAI++ L AR++WD P+ DRAQIFLKAAD++S R + Sbjct: 84 PFNHGHKVAKFCYADKSLLNKAIEAALAARKEWDLKPIADRAQIFLKAADMLSGPRRAEI 143 Query: 184 VATTMLGQAKTIFQAEIDAAVELIDFLRFNTEAAAKVTKYKPISTPGVINEVIWRGMEGF 363 +A TM+GQ KT+ QAEIDAA ELIDF RFN + A ++ +PIS P N ++RG+EGF Sbjct: 144 LAKTMVGQGKTVIQAEIDAAAELIDFFRFNAKYAVELEGQQPISVPPSTNSTVYRGLEGF 203 Query: 364 WAAITPFNFTAIGGNLAATPALMGNSVLWKPTDSSILSNYTIYKILRECNLPPGVINFVP 543 AAI+PFNFTAIGGNLA PALMGN VLWKP+D+++L++Y +Y+ILRE LPP +I FVP Sbjct: 204 VAAISPFNFTAIGGNLAGAPALMGNVVLWKPSDTAMLASYAVYRILREAGLPPNIIQFVP 263 Query: 544 CAGSVFGKVITLNPNLAGINFTGSVNTFRVLLEEVGKNIYEYSSYPRLIGECGGKNFHFV 723 G +FG +T + +L GINFTGSV TF+ L ++V +N+ + ++PRL GECGGKNFHFV Sbjct: 264 ADGPLFGDTVTSSEHLCGINFTGSVPTFKHLWKQVAQNLDRFHTFPRLAGECGGKNFHFV 323 Query: 724 HETADLDNVSVSTVRSAFEYGGQKCSACSRLYAPESKWPALKEKIINILNQVKIDSPLVK 903 H +AD+++V T+RSAFEYGGQKCSACSRLY P S WP +K +++ +++K+ P Sbjct: 324 HRSADVESVVSGTLRSAFEYGGQKCSACSRLYVPHSLWPQIKGRLLEEHSRIKVGDPAED 383 Query: 904 -DTFYSAVIDKIAFDRIKSYIDYAENNNKLSIEYGGKCDDSVGYFVHPTVIRTSDPDDKI 1080 TF+SAVID +F RIK ++++A ++ L+I GGKCDDSVGYFV P ++ + DP + I Sbjct: 384 FGTFFSAVIDAKSFARIKKWLEHARSSPSLTILAGGKCDDSVGYFVEPCIVESKDPQEPI 443 Query: 1081 MKEEIFGPILSVYVYPDSAVEKTLELVDKTTPFGLTGAVFAEDEKFIEYATKKLRHSTGN 1260 MKEEIFGP+LSVYVYPD ++TL+LVD TT +GLTGAVF++D+ ++ ATK LR++ GN Sbjct: 444 MKEEIFGPVLSVYVYPDDKYKETLQLVDSTTSYGLTGAVFSQDKDVVQEATKVLRNAAGN 503 Query: 1261 FYINVQSTGSVVGQQPFGGSRLSRTNDKAGGPFYILKFLSMQSIKFQTGPVQSW 1422 FYIN +STGS+VGQQPFGG+R S TNDK GGP YIL++ S Q IK P+ W Sbjct: 504 FYINDKSTGSIVGQQPFGGARASGTNDKPGGPHYILRWTSPQVIKETHKPLGDW 557
>sp|Q8CHT0|AL4A1_MOUSE Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial precursor (P5C dehydrogenase) (Aldehyde dehydrogenase 4A1) Length = 562 Score = 559 bits (1440), Expect = e-159 Identities = 266/474 (56%), Positives = 356/474 (75%), Gaps = 1/474 (0%) Frame = +1 Query: 4 PFDHKKNLAQFYFADEKIINKAIKSCLEAREKWDKTPLKDRAQIFLKAADLMSKTYRPHL 183 PF+H +A+F +AD+ ++N+AI + L AR++WD P+ DRAQ+FLKAAD++S R + Sbjct: 83 PFNHAHKVAKFCYADKALLNRAIDAALAARKEWDLKPMADRAQVFLKAADMLSGPRRAEV 142 Query: 184 VATTMLGQAKTIFQAEIDAAVELIDFLRFNTEAAAKVTKYKPISTPGVINEVIWRGMEGF 363 +A TM+GQ KT+ QAEIDAA ELIDF RFN + A ++ +PIS P N ++RG+EGF Sbjct: 143 LAKTMVGQGKTVIQAEIDAAAELIDFFRFNAKFAVELEGEQPISVPPSTNHTVYRGLEGF 202 Query: 364 WAAITPFNFTAIGGNLAATPALMGNSVLWKPTDSSILSNYTIYKILRECNLPPGVINFVP 543 AAI+PFNFTAIGGNLA PALMGN VLWKP+D+++L++Y +Y+ILRE LPP +I FVP Sbjct: 203 VAAISPFNFTAIGGNLAGAPALMGNVVLWKPSDTAMLASYAVYRILREAGLPPNIIQFVP 262 Query: 544 CAGSVFGKVITLNPNLAGINFTGSVNTFRVLLEEVGKNIYEYSSYPRLIGECGGKNFHFV 723 G FG +T + +L GINFTGSV TF+ L +V +N+ + ++PRL GECGGKNFHFV Sbjct: 263 ADGPTFGDTVTSSEHLCGINFTGSVPTFKHLWRQVAQNLDRFRTFPRLAGECGGKNFHFV 322 Query: 724 HETADLDNVSVSTVRSAFEYGGQKCSACSRLYAPESKWPALKEKIINILNQVKIDSPLVK 903 H +AD+D+V T+RSAFEYGGQKCSACSRLY P+S WP +K +++ +++K+ P Sbjct: 323 HSSADVDSVVSGTLRSAFEYGGQKCSACSRLYVPKSLWPQIKGRLLEEHSRIKVGDPAED 382 Query: 904 -DTFYSAVIDKIAFDRIKSYIDYAENNNKLSIEYGGKCDDSVGYFVHPTVIRTSDPDDKI 1080 TF+SAVID AF RIK ++++A ++ LSI GG+C++SVGY+V P +I + DP + I Sbjct: 383 FGTFFSAVIDAKAFARIKKWLEHARSSPSLSILAGGQCNESVGYYVEPCIIESKDPQEPI 442 Query: 1081 MKEEIFGPILSVYVYPDSAVEKTLELVDKTTPFGLTGAVFAEDEKFIEYATKKLRHSTGN 1260 MKEEIFGP+L+VYVYPD +TL+LVD TT +GLTGAVFA+D+ ++ AT+ LR++ GN Sbjct: 443 MKEEIFGPVLTVYVYPDDKYRETLKLVDSTTSYGLTGAVFAQDKAIVQEATRMLRNAAGN 502 Query: 1261 FYINVQSTGSVVGQQPFGGSRLSRTNDKAGGPFYILKFLSMQSIKFQTGPVQSW 1422 FYIN +STGSVVGQQPFGG+R S TNDK GGP YIL++ S Q IK P+ W Sbjct: 503 FYINDKSTGSVVGQQPFGGARASGTNDKPGGPHYILRWTSPQVIKETHKPLGDW 556
>sp|O74766|PUT2_SCHPO Probable delta-1-pyrroline-5-carboxylate dehydrogenase (P5C dehydrogenase) Length = 548 Score = 442 bits (1137), Expect = e-123 Identities = 220/469 (46%), Positives = 319/469 (68%), Gaps = 5/469 (1%) Frame = +1 Query: 4 PFDHKKNLAQFYFADEKIINKAIKSCLEAREKWDKTPLKDRAQIFLKAADLMSKTYRPHL 183 PF+HKK +A+++ A K + AI++ L ++ W+ P DR+ IFLKAA L+S YR L Sbjct: 65 PFEHKKVVARYHRAGAKHVEDAIEAALRGKKVWESLPFADRSAIFLKAAHLISTKYRYKL 124 Query: 184 VATTMLGQAKTIFQAEIDAAVELIDFLRFNTEAAAKV-TKYKPISTPGVINEVIWRGMEG 360 +A TM+GQ K I+QAEIDA +E+IDFLRFNT+ A+++ P +TPGV N + +R +EG Sbjct: 125 MAATMIGQGKNIWQAEIDAGMEIIDFLRFNTKYASELYASQPPENTPGVWNRMEYRPLEG 184 Query: 361 FWAAITPFNFTAIGGNLAATPALMGNSVLWKPTDSSILSNYTIYKILRECNLPPGVINFV 540 F AITPFNFTAI GNLAA P LMGN VL KP+D ++LS+Y +Y+I RE LP G + F+ Sbjct: 185 FVYAITPFNFTAIAGNLAAAPLLMGNVVLMKPSDHAVLSSYIVYQIFREAGLPAGALQFI 244 Query: 541 PCAGSVFGKVITLNPNLAGINFTGSVNTFRVLLEEVGKNIY--EYSSYPRLIGECGGKNF 714 P KV +P AG++FTGS FR L +G+N+ +Y +YP+++GE GGKNF Sbjct: 245 PGDAVEVSKVCFNHPEFAGLHFTGSTAVFRSLWGTIGENVANGKYRTYPKIVGETGGKNF 304 Query: 715 HFVHETADLDNVSVSTVRSAFEYGGQKCSACSRLYAPESKWP-ALKEKIINILNQVKIDS 891 H VH +A++ + V+ VR+AFEY GQKCSA SRLY + W ++++ + +K+ + Sbjct: 305 HLVHSSAEIKSAVVNAVRAAFEYQGQKCSALSRLYVSKYAWENGFRDELTKQVKSLKVGA 364 Query: 892 PLVK-DTFYSAVIDKIAFDRIKSYIDYAENNNKLSIEYGGKCDDSVGYFVHPTVIRTSDP 1068 PL F VI + +F+++K ++ A +++++ + GGK DDS G+FV PTV+ + +P Sbjct: 365 PLTDFANFVGPVIHQASFNKLKKVLESAASDSEIEVLAGGKADDSEGFFVEPTVLLSKNP 424 Query: 1069 DDKIMKEEIFGPILSVYVYPDSAVEKTLELVDKTTPFGLTGAVFAEDEKFIEYATKKLRH 1248 I E+FGP+LSVYVY D ++ +L+D TTP+GLTG++FA+D + T +LR+ Sbjct: 425 KHDIFVNELFGPVLSVYVYEDDNLDAVCDLIDTTTPYGLTGSIFAQDRVVVRKLTDRLRN 484 Query: 1249 STGNFYINVQSTGSVVGQQPFGGSRLSRTNDKAGGPFYILKFLSMQSIK 1395 + GNFYIN + TG+VVG+QPFGG+R S TNDKAG + +F+S +SIK Sbjct: 485 AAGNFYINDKCTGAVVGEQPFGGARASGTNDKAGSGMILSRFVSPRSIK 533
>sp|Q9P8I0|PUT2_EMENI Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial precursor (P5C dehydrogenase) Length = 572 Score = 421 bits (1081), Expect = e-117 Identities = 219/468 (46%), Positives = 303/468 (64%), Gaps = 6/468 (1%) Frame = +1 Query: 25 LAQFYFADEKIINKAIKSCLEAREKWDKTPLKDRAQIFLKAADLMSKTYRPHLVATTMLG 204 +A + A K + AI+S LEAR+ W TP DRA +FLKAADL+S YR ++A TM G Sbjct: 94 VATYSNATAKDVQAAIESALEARKSWASTPFADRASVFLKAADLISTKYRYDVMAVTMHG 153 Query: 205 QAKTIFQAEIDAAVELIDFLRFNTEAAAKVTKYKPIS-TPGVINEVIWRGMEGFWAAITP 381 Q K +QAEID+A EL DF RF + A + +P+ PGV N V +R +EGF AI+P Sbjct: 154 QGKNAWQAEIDSAAELCDFFRFGVKYAEDLYAQQPVHHAPGVWNRVEYRPLEGFVYAISP 213 Query: 382 FNFTAIGGNLAATPALMGNSVLWKPTDSSILSNYTIYKILRECNLPPGVINFVPCAGSVF 561 FNFTAIGGNLA PALMGN V+WKP+ S+I SN+ +++IL E LP VI FVP Sbjct: 214 FNFTAIGGNLAGAPALMGNVVVWKPSPSAIASNWLVHQILLEAGLPKNVIQFVPGEAEEV 273 Query: 562 GKVITLNPNLAGINFTGSVNTFRVLLEEVGKNIY--EYSSYPRLIGECGGKNFHFVHETA 735 K + +P+ A ++FTGS N FR L ++ + +Y SYPR++GE GGKNFH +H++A Sbjct: 274 TKTVLDHPDFAALHFTGSTNVFRNLYGQISTRVAAGKYRSYPRIVGETGGKNFHLIHKSA 333 Query: 736 DLDNVSVSTVRSAFEYGGQKCSACSRLYAPESKWPALKEKIINILNQVKIDSPLVKDTFY 915 D+ N +V TVR AFEY GQKCSA SR+Y S + E++ + +K+ P F Sbjct: 334 DIRNAAVQTVRGAFEYQGQKCSATSRVYVASSIADSFLEQVASEAKSLKVGPPSDFTNFC 393 Query: 916 SAVIDKIAFDRIKSYIDYAENNNKLSIEYGGKCDDSVGYFVHPTVIRTSDPDDKIMKEEI 1095 VI + +F ++ ID A+N+ +L + GG D S G+++ PTV RT++PD ++ E+ Sbjct: 394 GPVIHEASFTKLAKVIDEAKNDPELELLAGGSYDSSKGWYIQPTVYRTTNPDHPLLTREL 453 Query: 1096 FGPILSVYVYPDSA---VEKTLELVDKTTPFGLTGAVFAEDEKFIEYATKKLRHSTGNFY 1266 FGPIL VY YPD+ + + +D T +GLTG+VFA+D + + A LR++ GNFY Sbjct: 454 FGPILVVYAYPDATEADFARIAQKIDATGEYGLTGSVFAQDREALAVANDVLRNAAGNFY 513 Query: 1267 INVQSTGSVVGQQPFGGSRLSRTNDKAGGPFYILKFLSMQSIKFQTGP 1410 IN +STG+VVGQQPFGG+R S TNDKAG + +F+S++SIK + P Sbjct: 514 INCKSTGAVVGQQPFGGARASGTNDKAGSGNLLSRFVSLRSIKEEFVP 561
>sp|P78568|PUT2_AGABI Delta-1-pyrroline-5-carboxylate dehydrogenase (P5C dehydrogenase) Length = 546 Score = 411 bits (1057), Expect = e-114 Identities = 211/466 (45%), Positives = 295/466 (63%), Gaps = 2/466 (0%) Frame = +1 Query: 4 PFDHKKNLAQFYFADEKIINKAIKSCLEAREKWDKTPLKDRAQIFLKAADLMSKTYRPHL 183 P DH ++L F+ +++ KA L+A++ W+ P DRA IFLKAADL S YR L Sbjct: 67 PHDHARHLCTFHEGSPELVEKATCGALQAKDGWETMPWNDRAAIFLKAADLASGKYRYKL 126 Query: 184 VATTMLGQAKTIFQAEIDAAVELIDFLRFNTEAAAKV-TKYKPISTPGVINEVIWRGMEG 360 +A TMLGQ K +QAEIDAA EL DF RF ++ + P + PG N +R +EG Sbjct: 127 MAATMLGQGKNTWQAEIDAAAELADFFRFGVSYVEELYAQQPPKNAPGCWNRTEYRPLEG 186 Query: 361 FWAAITPFNFTAIGGNLAATPALMGNSVLWKPTDSSILSNYTIYKILRECNLPPGVINFV 540 F A++PFNFTAIGGNL +PAL+GN V+WKP ++ SNY ++KIL E +PPGVI F+ Sbjct: 187 FVLAVSPFNFTAIGGNLPGSPALVGNVVVWKPAPAATYSNYLVFKILSEAGVPPGVIQFI 246 Query: 541 PCAGSVFGKVITLNPNLAGINFTGSVNTFRVLLEEVGKNIYEYSSYPRLIGECGGKNFHF 720 P + I +PN ++FTGS N F+ L +++ N+ +Y YPR++GE GGKN+H Sbjct: 247 PGGAEIVQAAIQ-SPNFRSLHFTGSTNVFKSLWKDISSNLDKYKVYPRIVGETGGKNWHV 305 Query: 721 VHETADLDNVSVSTVRSAFEYGGQKCSACSRLYAPESKWP-ALKEKIINILNQVKIDSPL 897 +H++A++ N + +VR AFEY GQKCSA SRLY S W K + + + ++K+ L Sbjct: 306 IHKSAEVRNAVLQSVRGAFEYQGQKCSALSRLYVSRSVWENGFKTQYLEEIAKIKVGPCL 365 Query: 898 VKDTFYSAVIDKIAFDRIKSYIDYAENNNKLSIEYGGKCDDSVGYFVHPTVIRTSDPDDK 1077 + + VI + A+D I +I A+ + GG DDS G+F+ PTVI T P Sbjct: 366 DWNNYMGPVIGRRAYDNITGFIKKAKEEGG-EVLIGGSGDDSKGFFIQPTVILTKVPRST 424 Query: 1078 IMKEEIFGPILSVYVYPDSAVEKTLELVDKTTPFGLTGAVFAEDEKFIEYATKKLRHSTG 1257 M EIFGP+++ YV+ DS EKTLEL+D T+ +GLTGA+FA + + + AT + R++ G Sbjct: 425 TMVGEIFGPVVTAYVFEDSDYEKTLELIDTTSIYGLTGAIFASERQALLTATNRSRNAAG 484 Query: 1258 NFYINVQSTGSVVGQQPFGGSRLSRTNDKAGGPFYILKFLSMQSIK 1395 N Y N + TG+VVGQQPFGG+R S TNDKAG +F+S +SIK Sbjct: 485 NIYYNEKCTGAVVGQQPFGGARGSGTNDKAGSISIFYRFVSARSIK 530
>sp|P07275|PUT2_YEAST Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial precursor (P5C dehydrogenase) Length = 575 Score = 403 bits (1035), Expect = e-112 Identities = 211/476 (44%), Positives = 299/476 (62%), Gaps = 12/476 (2%) Frame = +1 Query: 4 PFDHKKNLAQFYFADEKIINKAIKSCLEAREKWDKTPLKDRAQIFLKAADLMSKTYRPHL 183 P +H++ LA A EK + A+K+ +A++ W P DR+ IFLKAADL+S YR + Sbjct: 84 PANHQQVLANVTQATEKDVMNAVKAAKDAKKDWYNLPFYDRSAIFLKAADLISTKYRYDM 143 Query: 184 VATTMLGQAKTIFQAEIDAAVELIDFLRFNTEAAAKVTKYKPI-STPGVINEVIWRGMEG 360 +A TMLGQ K ++QAEID EL DF R+ + A+ + +P+ S G N+ +R +EG Sbjct: 144 LAATMLGQGKNVYQAEIDCITELSDFFRYYVKYASDLYAQQPVESADGTWNKAEYRPLEG 203 Query: 361 FWAAITPFNFTAIGGNLAATPALMGNSVLWKPTDSSILSNYTIYKILRECNLPPGVINFV 540 F A++PFNFTAI NL PALMGN+V+WKP+ ++ LSNY + +L E LP GVINF+ Sbjct: 204 FVYAVSPFNFTAIAANLIGAPALMGNTVVWKPSQTAALSNYLLMTVLEEAGLPKGVINFI 263 Query: 541 PCAGSVFGKVITLNPNLAGINFTGSVNTFRVLLEEVGKNIYE--YSSYPRLIGECGGKNF 714 P + + + ++FTGS N F+ L ++ + E Y YPR+IGE GGKNF Sbjct: 264 PGDPVQVTDQVLADKDFGALHFTGSTNVFKSLYGKIQSGVVEGKYRDYPRIIGETGGKNF 323 Query: 715 HFVHETADLDNVSVSTVRSAFEYGGQKCSACSRLYAPESKWPALKEKIINILNQVKI--- 885 H VH +A++ + +ST+R FE+ GQKCSA SRLY PESK + IL + Sbjct: 324 HLVHPSANISHAVLSTIRGTFEFQGQKCSAASRLYLPESKSEEFLSDMFGILQSQNVVPM 383 Query: 886 ---DSPLVKDT---FYSAVIDKIAFDRIKSYIDYAENNNKLSIEYGGKCDDSVGYFVHPT 1047 SP+ F VI + +FD++ I+ A+ + +L I YGG+ D S G+FV PT Sbjct: 384 NTSASPISGGNLRGFMGPVIHEQSFDKLVKVIEDAKKDPELEILYGGQYDKSQGWFVGPT 443 Query: 1048 VIRTSDPDDKIMKEEIFGPILSVYVYPDSAVEKTLELVDKTTPFGLTGAVFAEDEKFIEY 1227 VI+ PD M E FGPIL+VY YPD+ + +++D T+ + LTGA+FA+D K IEY Sbjct: 444 VIKAKRPDHPYMSTEFFGPILTVYEYPDTEFNEICDIIDNTSQYALTGAIFAKDRKAIEY 503 Query: 1228 ATKKLRHSTGNFYINVQSTGSVVGQQPFGGSRLSRTNDKAGGPFYILKFLSMQSIK 1395 A +KL+ S GNFYIN + TG+VV QQ FGG+R+S T+DKAGGP + +F+S+++ K Sbjct: 504 ADEKLKFSAGNFYINDKCTGAVVSQQWFGGARMSGTDDKAGGPNILSRFVSIRNTK 559
>sp|Q8ERF4|ROCA_OCEIH 1-pyrroline-5-carboxylate dehydrogenase (P5C dehydrogenase) Length = 515 Score = 242 bits (617), Expect = 2e-63 Identities = 157/455 (34%), Positives = 250/455 (54%), Gaps = 5/455 (1%) Frame = +1 Query: 43 ADEKIINKAIKSCLEAREKWDKTPLKDRAQIFLKAADLMSKTYRPHLVATTMLGQA-KTI 219 A ++ I +A S EA ++W +DRA++ +AA ++ + R H + + A K Sbjct: 70 ATKQHIEEAFTSAKEAFKEWKSWSAEDRARVLYRAAAIVRR--RKHEFSAWLSYDAGKPW 127 Query: 220 FQAEIDAAVELIDFLRFNTEAAAKVTKYKPIST-PGVINEVIWRGMEGFWAAITPFNFT- 393 QA+ D A E IDFL + ++ K KP++ P N+ ++ + G I P+NF Sbjct: 128 DQADGDTA-EGIDFLEYYARHMVELEKGKPLADRPNEDNKYFYQPL-GPGVVIPPWNFAF 185 Query: 394 AIGGNLAATPALMGNSVLWKPTDSSILSNYTIYKILRECNLPPGVINFVPCAGSVFGKVI 573 AI P + GN VL KP++++ + Y + ++L E LP GV+NFVP + G + Sbjct: 186 AIVCGTTVAPIVAGNPVLLKPSENTPVIAYKLVEVLEEAGLPKGVLNFVPGDPAEIGDYL 245 Query: 574 TLNPNLAGINFTGSVNTFRVLLEEVGKNIYEYSSYPRLIGECGGKNFHFVHETADLDNVS 753 + + INFTGS T + E K + R++ E GGK+ V E+ADLD + Sbjct: 246 VDHKDTHFINFTGSRATGVRIFERATKIQDGQTHLKRIVAEMGGKDTIIVDESADLDLAA 305 Query: 754 VSTVRSAFEYGGQKCSACSRLYAPESKWPALKEKIINILNQVKIDSPLVKDTFYSAVIDK 933 S V SAF + GQKCSACSR ES + + EK + + + + +P + + ++V+++ Sbjct: 306 ESIVHSAFGFSGQKCSACSRAVIHESVYDEVIEKSVELAKTLTVGNPTEDNVYMASVVNQ 365 Query: 934 IAFDRIKSYIDYAENNNKLSIEYGGKCDDSVGYFVHPTVIRTSDPDDKIMKEEIFGPILS 1113 FD+IK YI+ + +L +GG+ DD+ G+FVHPT+ + DP +IM+EEIFGP+++ Sbjct: 366 KQFDKIKDYIEVGKQEGEL--VFGGETDDNKGFFVHPTIFKDLDPKARIMQEEIFGPVVA 423 Query: 1114 VYVYPDSAVEKTLELVD--KTTPFGLTGAVFAEDEKFIEYATKKLRHSTGNFYINVQSTG 1287 S + EL+D T +GLTGAV + + + + A + GN Y N T Sbjct: 424 F-----SKAKSFDELLDIANNTEYGLTGAVISNNRENLNRA--QTEFLVGNLYFNRGCTA 476 Query: 1288 SVVGQQPFGGSRLSRTNDKAGGPFYILKFLSMQSI 1392 ++VG QPFGG ++S T+ KAGGP Y+ FL+ + + Sbjct: 477 AIVGYQPFGGFKMSGTDSKAGGPDYLQHFLNAKVV 511
>sp|P39634|ROCA_BACSU 1-pyrroline-5-carboxylate dehydrogenase (P5C dehydrogenase) Length = 515 Score = 238 bits (608), Expect = 3e-62 Identities = 156/460 (33%), Positives = 250/460 (54%), Gaps = 11/460 (2%) Frame = +1 Query: 43 ADEKIINKAIKSCLEAREKWDKTPLKDRAQIFLKAADLMSKTYRPHLVATTMLGQA-KTI 219 AD+++ KA+++ L+A + W K + RA I KAA ++ + R H ++ ++ +A K Sbjct: 70 ADQELAEKAMQAALQAFDSWKKQRPEHRANILFKAAAILRR--RKHEFSSYLVKEAGKPW 127 Query: 220 FQAEIDAAVELIDFLRFNTEAAAKVTKYKPI-STPGVINEVIWRGMEGFWAAITPFNFT- 393 +A+ D A E IDFL F K+ + P+ S G +N+ + + G I+PFNF Sbjct: 128 KEADADTA-EAIDFLEFYARQMLKLKEGAPVKSRAGEVNQYHYEAL-GVGIVISPFNFPL 185 Query: 394 AIGGNLAATPALMGNSVLWKPTDSSILSNYTIYKILRECNLPPGVINFVPCAGSVFGKVI 573 AI A + GN++L KP D++ + +++ E LP GV+N++P G+ G + Sbjct: 186 AIMAGTAVAAIVTGNTILLKPADAAPVVAAKFVEVMEEAGLPNGVLNYIPGDGAEIGDFL 245 Query: 574 TLNPNLAGINFTGSVNTFRVLLEEVGKNIYEYSS--------YPRLIGECGGKNFHFVHE 729 +P ++FTGS VG IYE ++ R+I E GGK+ V + Sbjct: 246 VEHPKTRFVSFTGS--------RAVGCRIYERAAKVQPGQKWLKRVIAEMGGKDTVLVDK 297 Query: 730 TADLDNVSVSTVRSAFEYGGQKCSACSRLYAPESKWPALKEKIINILNQVKIDSPLVKDT 909 ADLD + S V SAF Y GQKCSA SR + + + EK + + + + +P DT Sbjct: 298 DADLDLAASSIVYSAFGYSGQKCSAGSRAVIHQDVYDEVVEKAVALTKTLTVGNPEDPDT 357 Query: 910 FYSAVIDKIAFDRIKSYIDYAENNNKLSIEYGGKCDDSVGYFVHPTVIRTSDPDDKIMKE 1089 + VI + +++++ YI+ ++ KL GG+ DDS GYF+ PT+ D + ++M+E Sbjct: 358 YMGPVIHEASYNKVMKYIEIGKSEGKLLA--GGEGDDSKGYFIQPTIFADVDENARLMQE 415 Query: 1090 EIFGPILSVYVYPDSAVEKTLELVDKTTPFGLTGAVFAEDEKFIEYATKKLRHSTGNFYI 1269 EIFGP++++ D + LE+ + T +GLTGA+ ++ IE A + GN Y Sbjct: 416 EIFGPVVAICKARD--FDHMLEIAN-NTEYGLTGALLTKNRAHIERAREDFH--VGNLYF 470 Query: 1270 NVQSTGSVVGQQPFGGSRLSRTNDKAGGPFYILKFLSMQS 1389 N TG++VG QPFGG +S T+ KAGGP Y++ L MQ+ Sbjct: 471 NRGCTGAIVGYQPFGGFNMSGTDSKAGGPDYLI--LHMQA 508
>sp|Q4L966|ROCA_STAHJ 1-pyrroline-5-carboxylate dehydrogenase (P5C dehydrogenase) Length = 514 Score = 237 bits (604), Expect = 7e-62 Identities = 156/474 (32%), Positives = 249/474 (52%), Gaps = 11/474 (2%) Frame = +1 Query: 4 PFDHKKNLAQFYFADEKIINKAIKSCLEAREKWDKTPLKDRAQIFLKAADLMSKTYRPHL 183 P + + +A+ A ++ ++KA +S +A + W + KDRA++ L+ A ++ + R Sbjct: 57 PANTSELIAKVSKATKEDVDKAFESSNKAYKAWRQWSHKDRAELLLRVAAIIRR--RKEE 114 Query: 184 VATTMLGQAKTIFQAEIDAAVELIDFLRFNTEAAAKVTKYKPI-STPGVINEVIWRGMEG 360 ++ M+ +A + + A E IDF+ + + ++ KP+ G N+ ++ + G Sbjct: 115 ISAVMVYEAGKPWDEAVGDAAEGIDFIEYYARSMMELADGKPVLDREGEHNKYFYKSI-G 173 Query: 361 FWAAITPFNFT-AIGGNLAATPALMGNSVLWKPTDSSILSNYTIYKILRECNLPPGVINF 537 I P+NF AI P + GN+VL KP + ++L+ Y + +IL E LP GV+NF Sbjct: 174 TGVTIPPWNFPFAIMAGTTLAPVVAGNTVLLKPAEDTVLTAYKLIEILEEAGLPKGVVNF 233 Query: 538 VPCAGSVFGKVITLNPNLAGINFTGSVNTFRVLLEEVGKNIYEYSS--------YPRLIG 693 VP G + + + + FTGS T G IYE S+ R+I Sbjct: 234 VPGDPKEIGDYLVDSVHTHFVTFTGSRAT--------GTRIYERSAVVQEGQTFLKRVIA 285 Query: 694 ECGGKNFHFVHETADLDNVSVSTVRSAFEYGGQKCSACSRLYAPESKWPALKEKIINILN 873 E GGK+ V E D D + S + SAF + GQKCSACSR S + + EK + + Sbjct: 286 EMGGKDAIVVDENIDTDLAAESIITSAFGFSGQKCSACSRAIVHSSVYDEVLEKAVALTK 345 Query: 874 QVKIDSPLVKDTFYSAVIDKIAFDRIKSYIDYAENNNKLSIEYGGKCDDSVGYFVHPTVI 1053 ++ + + V +TF VI+K FD+IK YI+ K IE GG+ DDS GYF+ PT+I Sbjct: 346 ELTVGN-TVDNTFMGPVINKKQFDKIKKYIEIGGKEGK--IEIGGEADDSTGYFIKPTII 402 Query: 1054 RTSDPDDKIMKEEIFGPILSVYVYPDSAVEKTLELVDKTTPFGLTGAVFAED-EKFIEYA 1230 D++M+EEIFGP++ + + E+ +E+ + T +GLTGAV + E +I+ Sbjct: 403 SGLKSSDQVMQEEIFGPVVGFTKFDN--FEEAIEIAN-DTDYGLTGAVITNNRENWIKAV 459 Query: 1231 TKKLRHSTGNFYINVQSTGSVVGQQPFGGSRLSRTNDKAGGPFYILKFLSMQSI 1392 + GN Y+N T +VVG PFGG ++S T+ K G P Y+L FL + + Sbjct: 460 NE---FDVGNLYLNRGCTAAVVGYHPFGGFKMSGTDAKTGSPDYLLNFLEQKVV 510
>sp|Q9K9B2|ROCA1_BACHD 1-pyrroline-5-carboxylate dehydrogenase 1 (P5C dehydrogenase 1) Length = 515 Score = 236 bits (601), Expect = 2e-61 Identities = 157/461 (34%), Positives = 247/461 (53%), Gaps = 11/461 (2%) Frame = +1 Query: 43 ADEKIINKAIKSCLEAREKWDKTPLKDRAQIFLKAADLMSKTYRPHLVATTMLGQA-KTI 219 A++ + KAI+S EA + W ++RA I +KAA ++ + R H + ++ +A K Sbjct: 70 ANQDLAEKAIQSADEAFQTWRNVNPEERANILVKAAAIIRR--RKHEFSAWLVHEAGKPW 127 Query: 220 FQAEIDAAVELIDFLRFNTEAAAKVTKYKPI-STPGVINEVIWRGMEGFWAAITPFNFT- 393 +A+ D A E IDFL + ++ + K I S PG N + M G I+P+NF Sbjct: 128 KEADADTA-EAIDFLEYYARQMIELNRGKEILSRPGEQNRYFYTPM-GVTVTISPWNFAL 185 Query: 394 AIGGNLAATPALMGNSVLWKPTDSSILSNYTIYKILRECNLPPGVINFVPCAGSVFGKVI 573 AI A P + GN+V+ KP ++ + ++L + LP GVIN+VP +G+ G + Sbjct: 186 AIMVGTAVAPIVTGNTVVLKPASTTPVVAAKFVEVLEDAGLPKGVINYVPGSGAEVGDYL 245 Query: 574 TLNPNLAGINFTGSVNTFRVLLEEVGKNIYEYSSY--------PRLIGECGGKNFHFVHE 729 +P + I FTGS ++VG +YE ++ R+I E GGK+ V Sbjct: 246 VDHPKTSLITFTGS--------KDVGVRLYERAAVVRPGQNHLKRVIVEMGGKDTVVVDR 297 Query: 730 TADLDNVSVSTVRSAFEYGGQKCSACSRLYAPESKWPALKEKIINILNQVKIDSPLVKDT 909 ADLD + S + SAF + GQKCSA SR + + + EK + + + + P +D Sbjct: 298 DADLDLAAESILVSAFGFSGQKCSAGSRAVIHKDVYDEVLEKTVALAKNLTVGDPTNRDN 357 Query: 910 FYSAVIDKIAFDRIKSYIDYAENNNKLSIEYGGKCDDSVGYFVHPTVIRTSDPDDKIMKE 1089 + VID+ AF++I SYI+ + +L GG+ D S G+F+ PT+I DP+ IM+E Sbjct: 358 YMGPVIDEKAFEKIMSYIEIGKKEGRLMT--GGEGDSSTGFFIQPTIIADLDPEAVIMQE 415 Query: 1090 EIFGPILSVYVYPDSAVEKTLELVDKTTPFGLTGAVFAEDEKFIEYATKKLRHSTGNFYI 1269 EIFGP+++ D + LE+ + T +GLTGAV + IE A ++ GN Y Sbjct: 416 EIFGPVVAFSKAND--FDHALEIAN-NTEYGLTGAVITRNRAHIEQAKREFH--VGNLYF 470 Query: 1270 NVQSTGSVVGQQPFGGSRLSRTNDKAGGPFYILKFLSMQSI 1392 N TG++VG PFGG ++S T+ KAGGP Y+ + +++ Sbjct: 471 NRNCTGAIVGYHPFGGFKMSGTDSKAGGPDYLALHMQAKTV 511
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 167,014,916
Number of Sequences: 369166
Number of extensions: 3491422
Number of successful extensions: 9710
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 8867
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 9320
length of database: 68,354,980
effective HSP length: 115
effective length of database: 47,110,455
effective search space used: 17807751990
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
Cluster detail
