Planaria EST Database

DrC_00377

BLASTX 2.2.13 [Nov-27-2005]

Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= DrC_00377
         (817 letters)

Database: Non-redundant SwissProt sequences 
           184,735 sequences; 68,354,980 total letters



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

sp|Q63474|DDR1_RAT  Epithelial discoidin domain receptor 1 p...    58   4e-08
sp|Q03146|DDR1_MOUSE  Epithelial discoidin domain receptor 1...    56   1e-07
sp|Q08345|DDR1_HUMAN  Epithelial discoidin domain receptor 1...    54   5e-07
sp|Q7YR43|DDR1_PANTR  Epithelial discoidin domain receptor 1...    54   5e-07
sp|Q62371|DDR2_MOUSE  Discoidin domain receptor 2 precursor ...    37   0.050
sp|Q16832|DDR2_HUMAN  Discoidin domain receptor 2 precursor ...    37   0.065

>sp|Q63474|DDR1_RAT Epithelial discoidin domain receptor 1 precursor (Tyrosine kinase
           DDR) (Discoidin receptor tyrosine kinase)
           (Tyrosine-protein kinase CAK) (Cell adhesion kinase)
           (Protein-tyrosine kinase PTK-3)
          Length = 910

 Score = 57.8 bits (138), Expect = 4e-08
 Identities = 35/123 (28%), Positives = 60/123 (48%)
 Frame = +2

Query: 50  YVGWNRNEIGSSSDQSVTLWFRFDSVRNFSYVKLYIFENQTLQITRPEKLEAKFSLKGDT 229
           YVGW+ +   S     V + F FD +R+F  ++++     TL    P  +E +F  +G  
Sbjct: 256 YVGWSNHSFPSGY---VEMEFEFDRLRSFQTMQVHCNNMHTLGARLPGGVECRFK-RGPA 311

Query: 230 FSQKNTIIAHSPETVSGSFSDSNSPWIQFNMQQKIGQYLQLKLYFQTEWILLSEIDFISE 409
            + +   + H+   + GS  D  +  I   +   +G++LQ +  F   W+L SEI FIS+
Sbjct: 312 MAWEGEPVHHA---LGGSLGDPRARAISVPLGGHVGRFLQCRFLFAGPWLLFSEISFISD 368

Query: 410 TAN 418
             N
Sbjct: 369 VVN 371

>sp|Q03146|DDR1_MOUSE Epithelial discoidin domain receptor 1 precursor (Tyrosine kinase
           DDR) (Discoidin receptor tyrosine kinase)
           (Tyrosine-protein kinase CAK) (Cell adhesion kinase)
           (Protein-tyrosine kinase MPK-6)
          Length = 911

 Score = 56.2 bits (134), Expect = 1e-07
 Identities = 34/123 (27%), Positives = 58/123 (47%)
 Frame = +2

Query: 50  YVGWNRNEIGSSSDQSVTLWFRFDSVRNFSYVKLYIFENQTLQITRPEKLEAKFSLKGDT 229
           YVGW+     +     V + F FD +R F  ++++     TL    P  +E +F  +G  
Sbjct: 257 YVGWSNQSFPTGY---VEMEFEFDRLRTFQTMQVHCNNMHTLGARLPGGVECRFK-RGPA 312

Query: 230 FSQKNTIIAHSPETVSGSFSDSNSPWIQFNMQQKIGQYLQLKLYFQTEWILLSEIDFISE 409
            + +   + H+   + GS  D  +  I   +   +G++LQ +  F   W+L SEI FIS+
Sbjct: 313 MAWEGEPVRHA---LGGSLGDPRARAISVPLGGHVGRFLQCRFLFAGPWLLFSEISFISD 369

Query: 410 TAN 418
             N
Sbjct: 370 VVN 372

>sp|Q08345|DDR1_HUMAN Epithelial discoidin domain receptor 1 precursor (Tyrosine kinase
           DDR) (Discoidin receptor tyrosine kinase)
           (Tyrosine-protein kinase CAK) (Cell adhesion kinase)
           (TRK E) (Protein-tyrosine kinase RTK 6) (CD167a antigen)
           (HGK2)
          Length = 913

 Score = 53.9 bits (128), Expect = 5e-07
 Identities = 32/123 (26%), Positives = 59/123 (47%)
 Frame = +2

Query: 50  YVGWNRNEIGSSSDQSVTLWFRFDSVRNFSYVKLYIFENQTLQITRPEKLEAKFSLKGDT 229
           YVGW+ +   S     V + F FD +R F  ++++     TL    P  +E +F  +G  
Sbjct: 255 YVGWSNHSFSSGY---VEMEFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFR-RGPA 310

Query: 230 FSQKNTIIAHSPETVSGSFSDSNSPWIQFNMQQKIGQYLQLKLYFQTEWILLSEIDFISE 409
            + +   + H+   + G+  D  +  +   +  ++ ++LQ +  F   W+L SEI FIS+
Sbjct: 311 MAWEGEPMRHN---LGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFSEISFISD 367

Query: 410 TAN 418
             N
Sbjct: 368 VVN 370

>sp|Q7YR43|DDR1_PANTR Epithelial discoidin domain receptor 1 precursor (Tyrosine kinase
           DDR) (Discoidin receptor tyrosine kinase)
          Length = 909

 Score = 53.9 bits (128), Expect = 5e-07
 Identities = 32/123 (26%), Positives = 59/123 (47%)
 Frame = +2

Query: 50  YVGWNRNEIGSSSDQSVTLWFRFDSVRNFSYVKLYIFENQTLQITRPEKLEAKFSLKGDT 229
           YVGW+ +   S     V + F FD +R F  ++++     TL    P  +E +F  +G  
Sbjct: 251 YVGWSNHSFSSGY---VEMEFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFR-RGPA 306

Query: 230 FSQKNTIIAHSPETVSGSFSDSNSPWIQFNMQQKIGQYLQLKLYFQTEWILLSEIDFISE 409
            + +   + H+   + G+  D  +  +   +  ++ ++LQ +  F   W+L SEI FIS+
Sbjct: 307 MAWEGEPMRHN---LGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFSEISFISD 363

Query: 410 TAN 418
             N
Sbjct: 364 VVN 366

>sp|Q62371|DDR2_MOUSE Discoidin domain receptor 2 precursor (Receptor protein-tyrosine
           kinase TKT) (Tyrosine-protein kinase TYRO 10)
           (Neurotrophic tyrosine kinase, receptor-related 3)
          Length = 854

 Score = 37.4 bits (85), Expect = 0.050
 Identities = 26/122 (21%), Positives = 58/122 (47%)
 Frame = +2

Query: 50  YVGWNRNEIGSSSDQSVTLWFRFDSVRNFSYVKLYIFENQTLQITRPEKLEAKFSLKGDT 229
           YVGW RNE  S+++  + + F FD +RNF+ +K++        +   ++++  F  +   
Sbjct: 256 YVGW-RNE--SATNGFIEIMFEFDRIRNFTTMKVHCNNMFAKGVKIFKEVQCYFRSEASE 312

Query: 230 FSQKNTIIAHSPETVSGSFSDSNSPWIQFNMQQKIGQYLQLKLYFQTEWILLSEIDFISE 409
           +           + V+ S     + ++   +  ++   ++ + +F   W++ SEI F S+
Sbjct: 313 WEPTAVYFPLVLDDVNPS-----ARFVTVPLHHRMASAIKCQYHFADTWMMFSEITFQSD 367

Query: 410 TA 415
            A
Sbjct: 368 AA 369

>sp|Q16832|DDR2_HUMAN Discoidin domain receptor 2 precursor (Receptor protein-tyrosine
           kinase TKT) (Tyrosine-protein kinase TYRO 10)
           (Neurotrophic tyrosine kinase, receptor-related 3)
          Length = 855

 Score = 37.0 bits (84), Expect = 0.065
 Identities = 26/122 (21%), Positives = 58/122 (47%)
 Frame = +2

Query: 50  YVGWNRNEIGSSSDQSVTLWFRFDSVRNFSYVKLYIFENQTLQITRPEKLEAKFSLKGDT 229
           YVGW RNE  S+++  + + F FD +RNF+ +K++        +   ++++  F  +   
Sbjct: 256 YVGW-RNE--SATNGYIEIMFEFDRIRNFTTMKVHCNNMFAKGVKIFKEVQCYFRSEASE 312

Query: 230 FSQKNTIIAHSPETVSGSFSDSNSPWIQFNMQQKIGQYLQLKLYFQTEWILLSEIDFISE 409
           +           + V+ S     + ++   +  ++   ++ + +F   W++ SEI F S+
Sbjct: 313 WEPNAISFPLVLDDVNPS-----ARFVTVPLHHRMASAIKCQYHFADTWMMFSEITFQSD 367

Query: 410 TA 415
            A
Sbjct: 368 AA 369

  Database: Non-redundant SwissProt sequences
    Posted date:  Dec 6, 2005  7:40 AM
  Number of letters in database: 68,354,980
  Number of sequences in database:  184,735
  
  Database: swissprot.01
    Posted date:  Dec 6, 2005  8:18 AM
  Number of letters in database: 66,202,850
  Number of sequences in database:  184,431
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 87,873,685
Number of Sequences: 369166
Number of extensions: 1605788
Number of successful extensions: 4281
Number of sequences better than 10.0: 6
Number of HSP's better than 10.0 without gapping: 4161
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4278
length of database: 68,354,980
effective HSP length: 109
effective length of database: 48,218,865
effective search space used: 7811456130
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)

Cluster detail

DrC_00377

  1. Dr_sW_019_P16
  2. Dr_sW_010_D09