Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_010_D09
(817 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q63474|DDR1_RAT Epithelial discoidin domain receptor 1 p... 58 4e-08
sp|Q03146|DDR1_MOUSE Epithelial discoidin domain receptor 1... 56 1e-07
sp|Q08345|DDR1_HUMAN Epithelial discoidin domain receptor 1... 54 5e-07
sp|Q7YR43|DDR1_PANTR Epithelial discoidin domain receptor 1... 54 5e-07
sp|Q62371|DDR2_MOUSE Discoidin domain receptor 2 precursor ... 37 0.050
sp|Q16832|DDR2_HUMAN Discoidin domain receptor 2 precursor ... 37 0.065
>sp|Q63474|DDR1_RAT Epithelial discoidin domain receptor 1 precursor (Tyrosine kinase
DDR) (Discoidin receptor tyrosine kinase)
(Tyrosine-protein kinase CAK) (Cell adhesion kinase)
(Protein-tyrosine kinase PTK-3)
Length = 910
Score = 57.8 bits (138), Expect = 4e-08
Identities = 35/123 (28%), Positives = 60/123 (48%)
Frame = +2
Query: 50 YVGWNRNEIGSSSDQSVTLWFRFDSVRNFSYVKLYIFENQTLQITRPEKLEAKFSLKGDT 229
YVGW+ + S V + F FD +R+F ++++ TL P +E +F +G
Sbjct: 256 YVGWSNHSFPSGY---VEMEFEFDRLRSFQTMQVHCNNMHTLGARLPGGVECRFK-RGPA 311
Query: 230 FSQKNTIIAHSPETVSGSFSDSNSPWIQFNMQQKIGQYLQLKLYFQTEWILLSEIDFISE 409
+ + + H+ + GS D + I + +G++LQ + F W+L SEI FIS+
Sbjct: 312 MAWEGEPVHHA---LGGSLGDPRARAISVPLGGHVGRFLQCRFLFAGPWLLFSEISFISD 368
Query: 410 TAN 418
N
Sbjct: 369 VVN 371
>sp|Q03146|DDR1_MOUSE Epithelial discoidin domain receptor 1 precursor (Tyrosine kinase
DDR) (Discoidin receptor tyrosine kinase)
(Tyrosine-protein kinase CAK) (Cell adhesion kinase)
(Protein-tyrosine kinase MPK-6)
Length = 911
Score = 56.2 bits (134), Expect = 1e-07
Identities = 34/123 (27%), Positives = 58/123 (47%)
Frame = +2
Query: 50 YVGWNRNEIGSSSDQSVTLWFRFDSVRNFSYVKLYIFENQTLQITRPEKLEAKFSLKGDT 229
YVGW+ + V + F FD +R F ++++ TL P +E +F +G
Sbjct: 257 YVGWSNQSFPTGY---VEMEFEFDRLRTFQTMQVHCNNMHTLGARLPGGVECRFK-RGPA 312
Query: 230 FSQKNTIIAHSPETVSGSFSDSNSPWIQFNMQQKIGQYLQLKLYFQTEWILLSEIDFISE 409
+ + + H+ + GS D + I + +G++LQ + F W+L SEI FIS+
Sbjct: 313 MAWEGEPVRHA---LGGSLGDPRARAISVPLGGHVGRFLQCRFLFAGPWLLFSEISFISD 369
Query: 410 TAN 418
N
Sbjct: 370 VVN 372
>sp|Q08345|DDR1_HUMAN Epithelial discoidin domain receptor 1 precursor (Tyrosine kinase
DDR) (Discoidin receptor tyrosine kinase)
(Tyrosine-protein kinase CAK) (Cell adhesion kinase)
(TRK E) (Protein-tyrosine kinase RTK 6) (CD167a antigen)
(HGK2)
Length = 913
Score = 53.9 bits (128), Expect = 5e-07
Identities = 32/123 (26%), Positives = 59/123 (47%)
Frame = +2
Query: 50 YVGWNRNEIGSSSDQSVTLWFRFDSVRNFSYVKLYIFENQTLQITRPEKLEAKFSLKGDT 229
YVGW+ + S V + F FD +R F ++++ TL P +E +F +G
Sbjct: 255 YVGWSNHSFSSGY---VEMEFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFR-RGPA 310
Query: 230 FSQKNTIIAHSPETVSGSFSDSNSPWIQFNMQQKIGQYLQLKLYFQTEWILLSEIDFISE 409
+ + + H+ + G+ D + + + ++ ++LQ + F W+L SEI FIS+
Sbjct: 311 MAWEGEPMRHN---LGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFSEISFISD 367
Query: 410 TAN 418
N
Sbjct: 368 VVN 370
>sp|Q7YR43|DDR1_PANTR Epithelial discoidin domain receptor 1 precursor (Tyrosine kinase
DDR) (Discoidin receptor tyrosine kinase)
Length = 909
Score = 53.9 bits (128), Expect = 5e-07
Identities = 32/123 (26%), Positives = 59/123 (47%)
Frame = +2
Query: 50 YVGWNRNEIGSSSDQSVTLWFRFDSVRNFSYVKLYIFENQTLQITRPEKLEAKFSLKGDT 229
YVGW+ + S V + F FD +R F ++++ TL P +E +F +G
Sbjct: 251 YVGWSNHSFSSGY---VEMEFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFR-RGPA 306
Query: 230 FSQKNTIIAHSPETVSGSFSDSNSPWIQFNMQQKIGQYLQLKLYFQTEWILLSEIDFISE 409
+ + + H+ + G+ D + + + ++ ++LQ + F W+L SEI FIS+
Sbjct: 307 MAWEGEPMRHN---LGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFSEISFISD 363
Query: 410 TAN 418
N
Sbjct: 364 VVN 366
>sp|Q62371|DDR2_MOUSE Discoidin domain receptor 2 precursor (Receptor protein-tyrosine
kinase TKT) (Tyrosine-protein kinase TYRO 10)
(Neurotrophic tyrosine kinase, receptor-related 3)
Length = 854
Score = 37.4 bits (85), Expect = 0.050
Identities = 26/122 (21%), Positives = 58/122 (47%)
Frame = +2
Query: 50 YVGWNRNEIGSSSDQSVTLWFRFDSVRNFSYVKLYIFENQTLQITRPEKLEAKFSLKGDT 229
YVGW RNE S+++ + + F FD +RNF+ +K++ + ++++ F +
Sbjct: 256 YVGW-RNE--SATNGFIEIMFEFDRIRNFTTMKVHCNNMFAKGVKIFKEVQCYFRSEASE 312
Query: 230 FSQKNTIIAHSPETVSGSFSDSNSPWIQFNMQQKIGQYLQLKLYFQTEWILLSEIDFISE 409
+ + V+ S + ++ + ++ ++ + +F W++ SEI F S+
Sbjct: 313 WEPTAVYFPLVLDDVNPS-----ARFVTVPLHHRMASAIKCQYHFADTWMMFSEITFQSD 367
Query: 410 TA 415
A
Sbjct: 368 AA 369
>sp|Q16832|DDR2_HUMAN Discoidin domain receptor 2 precursor (Receptor protein-tyrosine
kinase TKT) (Tyrosine-protein kinase TYRO 10)
(Neurotrophic tyrosine kinase, receptor-related 3)
Length = 855
Score = 37.0 bits (84), Expect = 0.065
Identities = 26/122 (21%), Positives = 58/122 (47%)
Frame = +2
Query: 50 YVGWNRNEIGSSSDQSVTLWFRFDSVRNFSYVKLYIFENQTLQITRPEKLEAKFSLKGDT 229
YVGW RNE S+++ + + F FD +RNF+ +K++ + ++++ F +
Sbjct: 256 YVGW-RNE--SATNGYIEIMFEFDRIRNFTTMKVHCNNMFAKGVKIFKEVQCYFRSEASE 312
Query: 230 FSQKNTIIAHSPETVSGSFSDSNSPWIQFNMQQKIGQYLQLKLYFQTEWILLSEIDFISE 409
+ + V+ S + ++ + ++ ++ + +F W++ SEI F S+
Sbjct: 313 WEPNAISFPLVLDDVNPS-----ARFVTVPLHHRMASAIKCQYHFADTWMMFSEITFQSD 367
Query: 410 TA 415
A
Sbjct: 368 AA 369
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 87,958,308
Number of Sequences: 369166
Number of extensions: 1608589
Number of successful extensions: 3973
Number of sequences better than 10.0: 6
Number of HSP's better than 10.0 without gapping: 3850
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3970
length of database: 68,354,980
effective HSP length: 109
effective length of database: 48,218,865
effective search space used: 7811456130
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)