Planaria EST Database

DrC_00289

BLASTX 2.2.13 [Nov-27-2005]

Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= DrC_00289
         (672 letters)

Database: Non-redundant SwissProt sequences 
           184,735 sequences; 68,354,980 total letters



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

sp|P98074|ENTK_PIG  Enteropeptidase precursor (Enterokinase)...    50   7e-06
sp|P97435|ENTK_MOUSE  Enteropeptidase (Enterokinase) [Contai...    47   5e-05
sp|Q9Y5Q5|CORIN_HUMAN  Atrial natriuteric peptide-converting...    45   1e-04
sp|Q9Z319|CORIN_MOUSE  Atrial natriuteric peptide-converting...    45   2e-04
sp|P98158|LRP2_RAT  Low-density lipoprotein receptor-related...    45   2e-04
sp|P98072|ENTK_BOVIN  Enteropeptidase precursor (Enterokinas...    44   3e-04
sp|P98162|RSVR_COTJA  Subgroup A Rous sarcoma virus receptor...    43   7e-04
sp|Q04833|LRP_CAEEL  Low-density lipoprotein receptor-relate...    43   7e-04
sp|P01130|LDLR_HUMAN  Low-density lipoprotein receptor precu...    43   7e-04
sp|Q07954|LRP1_HUMAN  Low-density lipoprotein receptor-relat...    42   0.001

>sp|P98074|ENTK_PIG Enteropeptidase precursor (Enterokinase) [Contains: Enteropeptidase
           non-catalytic mini chain; Enteropeptidase non-catalytic
           heavy chain; Enteropeptidase catalytic light chain]
          Length = 1034

 Score = 49.7 bits (117), Expect = 7e-06
 Identities = 28/66 (42%), Positives = 33/66 (50%), Gaps = 7/66 (10%)
 Frame = +1

Query: 52  YLTIAAFATEDKTGTSS-----GNGCPESQPW--PCKTPGKCLSFDFICDGEPDCPDKYD 210
           Y T +   T DK  TSS     GN   E  P   PC    KC++ D  CDGE +CPD  D
Sbjct: 171 YSTTSPSTTSDKLTTSSPPATPGNVSIECLPGSRPCADALKCIAVDLFCDGELNCPDGSD 230

Query: 211 EDQSLC 228
           ED  +C
Sbjct: 231 EDSKIC 236

>sp|P97435|ENTK_MOUSE Enteropeptidase (Enterokinase) [Contains: Enteropeptidase
           non-catalytic heavy chain; Enteropeptidase catalytic
           light chain]
          Length = 1069

 Score = 47.0 bits (110), Expect = 5e-05
 Identities = 27/63 (42%), Positives = 33/63 (52%), Gaps = 2/63 (3%)
 Frame = +1

Query: 46  LLYLTIAAFATEDKTGTSSGNGCPESQPW--PCKTPGKCLSFDFICDGEPDCPDKYDEDQ 219
           L  L+ A FAT      +SG+   E QP   PC     C++ D  CDGE +CPD  DED 
Sbjct: 210 LCNLSTATFAT------TSGHVSIECQPGSRPCAHAWNCVATDLFCDGEVNCPDGSDEDT 263

Query: 220 SLC 228
            LC
Sbjct: 264 GLC 266

>sp|Q9Y5Q5|CORIN_HUMAN Atrial natriuteric peptide-converting enzyme (pro-ANP-converting
           enzyme) (Corin) (Heart-specific serine proteinase ATC2)
           (Transmembrane protease, serine 10)
          Length = 1042

 Score = 45.4 bits (106), Expect = 1e-04
 Identities = 18/35 (51%), Positives = 20/35 (57%)
 Frame = +1

Query: 109 GCPESQPWPCKTPGKCLSFDFICDGEPDCPDKYDE 213
           GC E   W C +  +CL    ICDG PDCPD  DE
Sbjct: 615 GCKERDLWECPSNKQCLKHTVICDGFPDCPDYMDE 649


 Score = 36.6 bits (83), Expect = 0.061
 Identities = 12/27 (44%), Positives = 19/27 (70%)
 Frame = +1

Query: 148 GKCLSFDFICDGEPDCPDKYDEDQSLC 228
           G+C++ +++CDG+ DC DK DE    C
Sbjct: 353 GRCIAMEWVCDGDHDCVDKSDEVNCSC 379


 Score = 35.4 bits (80), Expect = 0.14
 Identities = 15/31 (48%), Positives = 18/31 (58%)
 Frame = +1

Query: 136 CKTPGKCLSFDFICDGEPDCPDKYDEDQSLC 228
           C T GKCL++  +CDG  DC D  DE    C
Sbjct: 313 CHT-GKCLNYSLVCDGYDDCGDLSDEQNCDC 342


 Score = 31.6 bits (70), Expect = 2.0
 Identities = 24/83 (28%), Positives = 33/83 (39%), Gaps = 12/83 (14%)
 Frame = +1

Query: 154 CLSFDFICDGEPDCPDKYDE------------DQSLCTAKNRPPYEVLEGFLQKYVSWLI 297
           C+S D  CDGE DC D  DE               L   +    + V     Q+ +S L 
Sbjct: 667 CVSRDLWCDGEADCSDSSDEWDCVTLSINVNSSSFLMVHRAATEHHVCADGWQEILSQLA 726

Query: 298 PKYLGQGSTAEITTRLIESTNAE 366
            K +G G  +   T+LI+    E
Sbjct: 727 CKQMGLGEPS--VTKLIQEQEKE 747


 Score = 30.8 bits (68), Expect = 3.3
 Identities = 11/23 (47%), Positives = 15/23 (65%)
 Frame = +1

Query: 148 GKCLSFDFICDGEPDCPDKYDED 216
           G+C+   F CDG+ DC D  DE+
Sbjct: 390 GQCIPSTFQCDGDEDCKDGSDEE 412


 Score = 30.4 bits (67), Expect = 4.4
 Identities = 14/36 (38%), Positives = 19/36 (52%)
 Frame = +1

Query: 148 GKCLSFDFICDGEPDCPDKYDEDQSLCTAKNRPPYE 255
           G+C+     CDG+ DC D  D D+  C  K R  +E
Sbjct: 590 GQCVLASRRCDGQADCDD--DSDEENCGCKERDLWE 623

>sp|Q9Z319|CORIN_MOUSE Atrial natriuteric peptide-converting enzyme (pro-ANP-converting
           enzyme) (Corin) (Low density lipoprotein
           receptor-related protein 4)
          Length = 1113

 Score = 45.1 bits (105), Expect = 2e-04
 Identities = 18/35 (51%), Positives = 19/35 (54%)
 Frame = +1

Query: 109 GCPESQPWPCKTPGKCLSFDFICDGEPDCPDKYDE 213
           GC E   W C    +CL    ICDG PDCPD  DE
Sbjct: 683 GCKERALWECPFNKQCLKHTLICDGFPDCPDSMDE 717


 Score = 35.8 bits (81), Expect = 0.10
 Identities = 12/27 (44%), Positives = 19/27 (70%)
 Frame = +1

Query: 148 GKCLSFDFICDGEPDCPDKYDEDQSLC 228
           G+C++ +++CDG+ DC DK DE    C
Sbjct: 421 GRCIAAEWVCDGDHDCVDKSDEVNCSC 447


 Score = 34.3 bits (77), Expect = 0.30
 Identities = 13/27 (48%), Positives = 15/27 (55%)
 Frame = +1

Query: 148 GKCLSFDFICDGEPDCPDKYDEDQSLC 228
           GKCL +  +CDG  DC D  DE    C
Sbjct: 384 GKCLHYSLLCDGYDDCGDPSDEQNCDC 410


 Score = 33.1 bits (74), Expect = 0.67
 Identities = 16/42 (38%), Positives = 22/42 (52%)
 Frame = +1

Query: 142 TPGKCLSFDFICDGEPDCPDKYDEDQSLCTAKNRPPYEVLEG 267
           T G+C+   F CDG+ DC D  DE+   C+    P  E  +G
Sbjct: 456 TSGQCIPSTFQCDGDEDCKDGSDEEN--CSDSQTPCPEGEQG 495


 Score = 30.4 bits (67), Expect = 4.4
 Identities = 14/36 (38%), Positives = 19/36 (52%)
 Frame = +1

Query: 148 GKCLSFDFICDGEPDCPDKYDEDQSLCTAKNRPPYE 255
           G+C+     CDG+ DC D  D D+  C  K R  +E
Sbjct: 658 GRCVLGSRRCDGQADCDD--DSDEENCGCKERALWE 691

>sp|P98158|LRP2_RAT Low-density lipoprotein receptor-related protein 2 precursor
           (Megalin) (Glycoprotein 330) (gp330)
          Length = 4660

 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 19/54 (35%), Positives = 28/54 (51%), Gaps = 8/54 (14%)
 Frame = +1

Query: 79  EDKTGTSSGNGCPESQP--------WPCKTPGKCLSFDFICDGEPDCPDKYDED 216
           +D   +   +GC  +Q         W C   G+C+S D +CDG PDCP+  DE+
Sbjct: 245 DDCQDSGDEDGCESNQSHHRCYpreWACPGSGRCISIDKVCDGVPDCPEGDDEN 298


 Score = 39.3 bits (90), Expect = 0.009
 Identities = 21/47 (44%), Positives = 28/47 (59%)
 Frame = +1

Query: 79   EDKTGTSSGNGCPESQPWPCKTPGKCLSFDFICDGEPDCPDKYDEDQ 219
            E  T   S N C  SQ + C   G+C+S +++CDG+ DC D  DEDQ
Sbjct: 2897 EPDTCGHSVNTCRASQ-FQCDN-GRCISGNWVCDGDNDCGDMSDEDQ 2941


 Score = 36.2 bits (82), Expect = 0.080
 Identities = 18/51 (35%), Positives = 24/51 (47%), Gaps = 4/51 (7%)
 Frame = +1

Query: 94   TSSGNGCPESQPWP----CKTPGKCLSFDFICDGEPDCPDKYDEDQSLCTA 234
            TS    CP     P    C+T   C+   F+CDG+ DC D  DE+   C +
Sbjct: 2812 TSDEKNCPPHTCPPDFTKCQTTNICVPRAFLCDGDNDCGDGSDENPIYCAS 2862


 Score = 35.8 bits (81), Expect = 0.10
 Identities = 18/53 (33%), Positives = 25/53 (47%), Gaps = 4/53 (7%)
 Frame = +1

Query: 76  TEDKTGTSSGNGCP----ESQPWPCKTPGKCLSFDFICDGEPDCPDKYDEDQS 222
           T D    +   GCP    ES  + C   G C+   ++CD + DC D  DE Q+
Sbjct: 50  TRDCLDDTDEIGCPPRSCESGLFLCPAEGTCIPSSWVCDEDKDCSDGADEQQN 102


 Score = 35.0 bits (79), Expect = 0.18
 Identities = 14/34 (41%), Positives = 19/34 (55%)
 Frame = +1

Query: 112  CPESQPWPCKTPGKCLSFDFICDGEPDCPDKYDE 213
            CP +Q W C     C++   +CDG  DCP+  DE
Sbjct: 1313 CPSTQ-WQCPGYSTCINLSALCDGVFDCPNGTDE 1345


 Score = 34.7 bits (78), Expect = 0.23
 Identities = 16/44 (36%), Positives = 21/44 (47%)
 Frame = +1

Query: 118  ESQPWPCKTPGKCLSFDFICDGEPDCPDKYDEDQSLCTAKNRPP 249
            ES  W C    +C+   + CD   DC D  DED S C ++   P
Sbjct: 3597 ESNEWQCANK-RCIPQSWQCDSVNDCLDNSDEDTSHCASRTCRP 3639


 Score = 34.7 bits (78), Expect = 0.23
 Identities = 18/43 (41%), Positives = 24/43 (55%)
 Frame = +1

Query: 100  SGNGCPESQPWPCKTPGKCLSFDFICDGEPDCPDKYDEDQSLC 228
            +G  CP +  + CK    C+   +ICDGE DC D  DE+  LC
Sbjct: 3840 NGTYCPAAM-FECKNH-VCIQSFWICDGENDCVDGSDEEIHLC 3880


 Score = 34.3 bits (77), Expect = 0.30
 Identities = 11/23 (47%), Positives = 18/23 (78%)
 Frame = +1

Query: 148 GKCLSFDFICDGEPDCPDKYDED 216
           G+C++ +++CDG+ DC D  DED
Sbjct: 232 GQCINQNWVCDGDDDCQDSGDED 254


 Score = 33.9 bits (76), Expect = 0.40
 Identities = 13/31 (41%), Positives = 18/31 (58%)
 Frame = +1

Query: 121  SQPWPCKTPGKCLSFDFICDGEPDCPDKYDE 213
            S  + C +P +C+   + CDGE DC D  DE
Sbjct: 2867 SNEFQCLSPQRCIPSYWFCDGEADCADGSDE 2897


 Score = 33.1 bits (74), Expect = 0.67
 Identities = 16/33 (48%), Positives = 18/33 (54%)
 Frame = +1

Query: 121  SQPWPCKTPGKCLSFDFICDGEPDCPDKYDEDQ 219
            S  +PC   GKC+   F CDG  DC D  DE Q
Sbjct: 1027 SLSFPCNN-GKCVPSFFRCDGVDDCHDNSDEHQ 1058


 Score = 33.1 bits (74), Expect = 0.67
 Identities = 21/67 (31%), Positives = 25/67 (37%), Gaps = 7/67 (10%)
 Frame = +1

Query: 82   DKTGTSSGNGCPESQP-------WPCKTPGKCLSFDFICDGEPDCPDKYDEDQSLCTAKN 240
            D    S   GCP   P       + C+  G C+   + CDG PDC    DE    C  K 
Sbjct: 1213 DCRDNSDEAGCPTRPPGMCHPDEFQCQGDGTCIPNTWECDGHPDCIHGSDEHTG-CVPKT 1271

Query: 241  RPPYEVL 261
              P   L
Sbjct: 1272 CSPTHFL 1278


 Score = 33.1 bits (74), Expect = 0.67
 Identities = 12/27 (44%), Positives = 17/27 (62%)
 Frame = +1

Query: 148  GKCLSFDFICDGEPDCPDKYDEDQSLC 228
            G+C+   F+CD + DC D  DE + LC
Sbjct: 3044 GRCIPRFFVCDEDNDCGDGSDEQEHLC 3070


 Score = 31.6 bits (70), Expect = 2.0
 Identities = 12/46 (26%), Positives = 21/46 (45%)
 Frame = +1

Query: 112  CPESQPWPCKTPGKCLSFDFICDGEPDCPDKYDEDQSLCTAKNRPP 249
            C  +  + C   G+C+   ++C+G  +C D    D+  C     PP
Sbjct: 2781 CNSTTEFTCSN-GRCIPLSYVCNGINNCHDNDTSDEKNCPPHTCPP 2825


 Score = 31.6 bits (70), Expect = 2.0
 Identities = 13/40 (32%), Positives = 20/40 (50%)
 Frame = +1

Query: 94   TSSGNGCPESQPWPCKTPGKCLSFDFICDGEPDCPDKYDE 213
            T++   C     + CKT  +C+    +C+G  DC D  DE
Sbjct: 3674 TTAAYNCDNHTEFSCKTNYRCIPQWAVCNGFDDCRDNSDE 3713


 Score = 30.8 bits (68), Expect = 3.3
 Identities = 12/27 (44%), Positives = 15/27 (55%)
 Frame = +1

Query: 148  GKCLSFDFICDGEPDCPDKYDEDQSLC 228
            G C S   +C+   DC D  DED+ LC
Sbjct: 3565 GNCTSPQALCNARQDCADGSDEDRVLC 3591


 Score = 30.4 bits (67), Expect = 4.4
 Identities = 15/44 (34%), Positives = 22/44 (50%)
 Frame = +1

Query: 82  DKTGTSSGNGCPESQPWPCKTPGKCLSFDFICDGEPDCPDKYDE 213
           D+    +G  C  +Q   C   G+C+  ++ CD   DCPD  DE
Sbjct: 98  DEQQNCAGTTC-SAQQMTCSN-GQCIPSEYRCDHVSDCPDGSDE 139


 Score = 30.4 bits (67), Expect = 4.4
 Identities = 16/47 (34%), Positives = 26/47 (55%), Gaps = 1/47 (2%)
 Frame = +1

Query: 76   TEDKTGTSSGNGCPESQPWPCKTPG-KCLSFDFICDGEPDCPDKYDE 213
            +++K   +SG      QP   + P  +C+S  ++CDG+ DC D  DE
Sbjct: 1139 SDEKNCQASGT----CQPTQFRCPDHRCISPLYVCDGDKDCADGSDE 1181


 Score = 30.0 bits (66), Expect = 5.7
 Identities = 12/29 (41%), Positives = 19/29 (65%)
 Frame = +1

Query: 151  KCLSFDFICDGEPDCPDKYDEDQSLCTAK 237
            +C+   ++CDG+ DC D  DE Q+ CT +
Sbjct: 2966 RCIPQYWVCDGDADCSDALDELQN-CTMR 2993


 Score = 29.6 bits (65), Expect = 7.5
 Identities = 11/27 (40%), Positives = 17/27 (62%)
 Frame = +1

Query: 148  GKCLSFDFICDGEPDCPDKYDEDQSLC 228
            G C++ D+ CD + DC D  DE  ++C
Sbjct: 2711 GHCINQDWKCDNDNDCGDGSDELPTVC 2737

>sp|P98072|ENTK_BOVIN Enteropeptidase precursor (Enterokinase) [Contains: Enteropeptidase
           non-catalytic heavy chain; Enteropeptidase catalytic
           light chain]
          Length = 1035

 Score = 44.3 bits (103), Expect = 3e-04
 Identities = 30/85 (35%), Positives = 39/85 (45%), Gaps = 9/85 (10%)
 Frame = +1

Query: 1   IINMAVILNSFFIGVLL--YLTIAAFATEDKTGTS-----SGNGCPESQPWP--CKTPGK 153
           ++   + LNS  I   L  + TI+   T +K  TS      GN   E  P    C    K
Sbjct: 152 LVTFHIDLNSIDITASLENFSTISPATTSEKLTTSIPLATPGNVSIECPPDSRLCADALK 211

Query: 154 CLSFDFICDGEPDCPDKYDEDQSLC 228
           C++ D  CDGE +CPD  DED   C
Sbjct: 212 CIAIDLFCDGELNCPDGSDEDNKTC 236


 Score = 30.8 bits (68), Expect = 3.3
 Identities = 18/46 (39%), Positives = 21/46 (45%), Gaps = 6/46 (13%)
 Frame = +1

Query: 94  TSSGNGCPESQPWPCKTP------GKCLSFDFICDGEPDCPDKYDE 213
           T  G G PE    PCK        G+C+    +CDG P C D  DE
Sbjct: 649 TGYGLGIPE----PCKEDNFQCKDGECIPLVNLCDGFPHCKDGSDE 690

>sp|P98162|RSVR_COTJA Subgroup A Rous sarcoma virus receptors PG800 and PG900 precursor
           (Low density lipoprotein receptor-related protein)
          Length = 157

 Score = 43.1 bits (100), Expect = 7e-04
 Identities = 23/50 (46%), Positives = 27/50 (54%), Gaps = 8/50 (16%)
 Frame = +1

Query: 88  TGTSSGNG----CPESQPWPCKTP----GKCLSFDFICDGEPDCPDKYDE 213
           TG  SGNG    CP  Q + C  P    G+C   D++CDG PDC D  DE
Sbjct: 18  TGNGSGNGSLSRCPPGQ-FRCSEPPGAHGECYPQDWLCDGHPDCDDGRDE 66

>sp|Q04833|LRP_CAEEL Low-density lipoprotein receptor-related protein precursor (LRP)
          Length = 4753

 Score = 43.1 bits (100), Expect = 7e-04
 Identities = 20/58 (34%), Positives = 30/58 (51%), Gaps = 3/58 (5%)
 Frame = +1

Query: 79   EDKTGTSSGNGCPES-QPW--PCKTPGKCLSFDFICDGEPDCPDKYDEDQSLCTAKNR 243
            +D   +S    C ++  PW   C   G+C+   F CDG+ DC D+ DE  +LC +  R
Sbjct: 3694 DDCGDSSDEQNCDKACDPWMFKCAATGRCIPRRFTCDGDDDCGDRSDEADTLCMSAER 3751


 Score = 39.7 bits (91), Expect = 0.007
 Identities = 17/45 (37%), Positives = 23/45 (51%)
 Frame = +1

Query: 112  CPESQPWPCKTPGKCLSFDFICDGEPDCPDKYDEDQSLCTAKNRP 246
            C +   + C T GKC+   ++CD E DC D  DE  + C    RP
Sbjct: 3833 CDDVGEFRCATSGKCIPRRWMCDTENDCGDNSDELDASCGGTTRP 3877


 Score = 37.4 bits (85), Expect = 0.036
 Identities = 19/45 (42%), Positives = 26/45 (57%)
 Frame = +1

Query: 79   EDKTGTSSGNGCPESQPWPCKTPGKCLSFDFICDGEPDCPDKYDE 213
            E K G +SG  C   Q + C   G+C+  +++CDGE DC D  DE
Sbjct: 1302 EPKFGCTSGRQCSSDQ-FKCGN-GRCILNNWLCDGENDCGDGSDE 1344


 Score = 36.6 bits (83), Expect = 0.061
 Identities = 14/37 (37%), Positives = 19/37 (51%)
 Frame = +1

Query: 136  CKTPGKCLSFDFICDGEPDCPDKYDEDQSLCTAKNRP 246
            C+   KC+   + CDG+ DC D  DED   C    +P
Sbjct: 1108 CRNTKKCIPAQYGCDGDNDCGDYSDEDVKYCKDGQKP 1144


 Score = 36.2 bits (82), Expect = 0.080
 Identities = 19/55 (34%), Positives = 26/55 (47%)
 Frame = +1

Query: 82   DKTGTSSGNGCPESQPWPCKTPGKCLSFDFICDGEPDCPDKYDEDQSLCTAKNRP 246
            D+    S   C E   +PC   G C++   +CDG  DC D+   D+SL T    P
Sbjct: 2864 DELDCPSAVACAEGT-FPCSN-GHCINQTKVCDGHNDCHDEQVSDESLATCPGLP 2916


 Score = 35.8 bits (81), Expect = 0.10
 Identities = 15/42 (35%), Positives = 23/42 (54%)
 Frame = +1

Query: 103  GNGCPESQPWPCKTPGKCLSFDFICDGEPDCPDKYDEDQSLC 228
            GN    +  + C   G+C+   ++CDG+ DC D  DED+  C
Sbjct: 1183 GNATCAANQFSCAN-GRCIPIYWLCDGDNDCYDGTDEDKERC 1223


 Score = 34.7 bits (78), Expect = 0.23
 Identities = 15/36 (41%), Positives = 18/36 (50%)
 Frame = +1

Query: 112 CPESQPWPCKTPGKCLSFDFICDGEPDCPDKYDEDQ 219
           CP  + W C   G C+    +CDG  DC D  DE Q
Sbjct: 262 CPPGK-WNCPGTGHCIDQLKLCDGSKDCADGADEQQ 296


 Score = 34.7 bits (78), Expect = 0.23
 Identities = 16/52 (30%), Positives = 27/52 (51%)
 Frame = +1

Query: 79   EDKTGTSSGNGCPESQPWPCKTPGKCLSFDFICDGEPDCPDKYDEDQSLCTA 234
            ED    ++ +  P+   + C + G C+   + CDG+ DC D  DE +  CT+
Sbjct: 1260 EDSCAVTAESCTPDQ--FKCVSSGLCIPASWKCDGQQDCDDGSDEPKFGCTS 1309


 Score = 34.7 bits (78), Expect = 0.23
 Identities = 12/33 (36%), Positives = 18/33 (54%)
 Frame = +1

Query: 148  GKCLSFDFICDGEPDCPDKYDEDQSLCTAKNRP 246
            G C+     CD +PDC D  DE+ + C  ++ P
Sbjct: 2803 GSCILLGATCDSKPDCADASDENPNYCNTRSCP 2835


 Score = 33.9 bits (76), Expect = 0.40
 Identities = 14/21 (66%), Positives = 15/21 (71%)
 Frame = +1

Query: 151  KCLSFDFICDGEPDCPDKYDE 213
            KC+S  FICDGE DC D  DE
Sbjct: 3018 KCISRAFICDGEDDCGDGSDE 3038


 Score = 33.5 bits (75), Expect = 0.52
 Identities = 12/28 (42%), Positives = 18/28 (64%)
 Frame = +1

Query: 148  GKCLSFDFICDGEPDCPDKYDEDQSLCT 231
            G+C+   + CDG+ DC D +DE  + CT
Sbjct: 2971 GRCIPETWQCDGDNDCSDGWDETHTNCT 2998


 Score = 33.1 bits (74), Expect = 0.67
 Identities = 15/33 (45%), Positives = 20/33 (60%), Gaps = 1/33 (3%)
 Frame = +1

Query: 154  CLSFDFICDGEPDCPDKYDEDQSLC-TAKNRPP 249
            C+   F+CDG+ DC D  DE  S C +A+  PP
Sbjct: 3971 CIPRKFMCDGDNDCGDNSDETSSECRSAQCDPP 4003


 Score = 32.7 bits (73), Expect = 0.88
 Identities = 17/50 (34%), Positives = 23/50 (46%), Gaps = 4/50 (8%)
 Frame = +1

Query: 112  CPESQ----PWPCKTPGKCLSFDFICDGEPDCPDKYDEDQSLCTAKNRPP 249
            CP  Q     + C    +C+     CDG+ DC D  DED    TA++  P
Sbjct: 1223 CPPVQCSALQFRCANGRQCVPLRNHCDGQSDCEDGSDEDSCAVTAESCTP 1272


 Score = 32.3 bits (72), Expect = 1.1
 Identities = 13/31 (41%), Positives = 16/31 (51%)
 Frame = +1

Query: 136  CKTPGKCLSFDFICDGEPDCPDKYDEDQSLC 228
            C     C+    +CDG  DC DK DE+Q  C
Sbjct: 2926 CPNTNICIQPADLCDGYDDCGDKADENQLFC 2956


 Score = 32.0 bits (71), Expect = 1.5
 Identities = 14/31 (45%), Positives = 20/31 (64%)
 Frame = +1

Query: 121  SQPWPCKTPGKCLSFDFICDGEPDCPDKYDE 213
            S  + CK  G+C+  ++ CDGE DC D+ DE
Sbjct: 1058 STQFQCKN-GRCIPKEWKCDGENDCLDESDE 1087


 Score = 32.0 bits (71), Expect = 1.5
 Identities = 14/27 (51%), Positives = 18/27 (66%), Gaps = 1/27 (3%)
 Frame = +1

Query: 151  KCLSFDFICDGEPDCPDKYDE-DQSLC 228
            KC+   + CDGEPDC D  DE  +S+C
Sbjct: 3640 KCIPKLWYCDGEPDCRDGSDEPGESIC 3666


 Score = 30.8 bits (68), Expect = 3.3
 Identities = 16/56 (28%), Positives = 24/56 (42%)
 Frame = +1

Query: 55  LTIAAFATEDKTGTSSGNGCPESQPWPCKTPGKCLSFDFICDGEPDCPDKYDEDQS 222
           +T  A  +++K   +S   C     + C    +C      CDG+ DC D  DE  S
Sbjct: 119 ITDCADGSDEKDCPASTVDCSSQNVFMCADGRQCFDVSKKCDGKYDCRDLSDEKDS 174


 Score = 30.8 bits (68), Expect = 3.3
 Identities = 11/31 (35%), Positives = 17/31 (54%)
 Frame = +1

Query: 136  CKTPGKCLSFDFICDGEPDCPDKYDEDQSLC 228
            C +  +C+     C+G+ DC D  DED+  C
Sbjct: 3800 CSSSYRCIPNWAFCNGQDDCRDNSDEDKQRC 3830


 Score = 30.4 bits (67), Expect = 4.4
 Identities = 15/57 (26%), Positives = 25/57 (43%), Gaps = 4/57 (7%)
 Frame = +1

Query: 76  TEDKTGTSSGNGCPESQPWPCKTPGKCLSFDFICDGEPDCPDKYDEDQSL----CTA 234
           +++K   S  +       + C    +C+   ++CDG  DC D  DE  +     CTA
Sbjct: 169 SDEKDSCSRNHTACFQYQFRCADKTQCIQKSWVCDGSKDCADGSDEPDTCEFKKCTA 225


 Score = 30.4 bits (67), Expect = 4.4
 Identities = 18/46 (39%), Positives = 23/46 (50%)
 Frame = +1

Query: 112  CPESQPWPCKTPGKCLSFDFICDGEPDCPDKYDEDQSLCTAKNRPP 249
            C ES+ + C   GKC+    +CDG   C D  DE Q  CT +   P
Sbjct: 3878 CSESE-FRCND-GKCIPGSKVCDGTIQCSDGLDESQ--CTLRRCLP 3919


 Score = 29.6 bits (65), Expect = 7.5
 Identities = 11/22 (50%), Positives = 14/22 (63%)
 Frame = +1

Query: 148 GKCLSFDFICDGEPDCPDKYDE 213
           GKC+  ++ CDG  DC D  DE
Sbjct: 63  GKCIRTEWKCDGSGDCSDGEDE 84

>sp|P01130|LDLR_HUMAN Low-density lipoprotein receptor precursor (LDL receptor)
          Length = 860

 Score = 43.1 bits (100), Expect = 7e-04
 Identities = 19/46 (41%), Positives = 28/46 (60%)
 Frame = +1

Query: 91  GTSSGNGCPESQPWPCKTPGKCLSFDFICDGEPDCPDKYDEDQSLC 228
           GT+ G+ C E   + C+  GKC+S+ ++CDG  +C D  DE Q  C
Sbjct: 20  GTAVGDRC-ERNEFQCQD-GKCISYKWVCDGSAECQDGSDESQETC 63


 Score = 33.5 bits (75), Expect = 0.52
 Identities = 18/45 (40%), Positives = 21/45 (46%), Gaps = 6/45 (13%)
 Frame = +1

Query: 97  SSGNGCPESQPWPCKTP------GKCLSFDFICDGEPDCPDKYDE 213
           S   GCP   P  C         GKC+S  F+CD + DC D  DE
Sbjct: 99  SDEQGCP---PKTCSQDEFRCHDGKCISRQFVCDSDRDCLDGSDE 140


 Score = 33.5 bits (75), Expect = 0.52
 Identities = 12/23 (52%), Positives = 16/23 (69%)
 Frame = +1

Query: 148 GKCLSFDFICDGEPDCPDKYDED 216
           G+C+   + CDG PDC DK DE+
Sbjct: 207 GECIHSSWRCDGGPDCKDKSDEE 229

>sp|Q07954|LRP1_HUMAN Low-density lipoprotein receptor-related protein 1 precursor (LRP)
            (Alpha-2-macroglobulin receptor) (A2MR) (Apolipoprotein E
            receptor) (APOER) (CD91)
          Length = 4544

 Score = 42.4 bits (98), Expect = 0.001
 Identities = 18/53 (33%), Positives = 27/53 (50%)
 Frame = +1

Query: 79   EDKTGTSSGNGCPESQPWPCKTPGKCLSFDFICDGEPDCPDKYDEDQSLCTAK 237
            +D T  +  + C     + C   G+C++F   CDG P C DK DE  S C ++
Sbjct: 2513 DDLTCRAVNSSCRAQDEFECAN-GECINFSLTCDGVPHCKDKSDEKPSYCNSR 2564


 Score = 40.4 bits (93), Expect = 0.004
 Identities = 16/40 (40%), Positives = 22/40 (55%)
 Frame = +1

Query: 136  CKTPGKCLSFDFICDGEPDCPDKYDEDQSLCTAKNRPPYE 255
            CK  G+C+   + CDGE DC D  DE +  C  +   PY+
Sbjct: 3501 CKDSGRCIPARWKCDGEDDCGDGSDEPKEECDERTCEPYQ 3540


 Score = 39.7 bits (91), Expect = 0.007
 Identities = 19/59 (32%), Positives = 32/59 (54%)
 Frame = +1

Query: 73   ATEDKTGTSSGNGCPESQPWPCKTPGKCLSFDFICDGEPDCPDKYDEDQSLCTAKNRPP 249
            ++++K+     + C  S  + CK   +C+S  ++CDG+ DC D  DE+     A  RPP
Sbjct: 1091 SSDEKSCEGVTHVCDPSVKFGCKDSARCISKAWVCDGDNDCEDNSDEENCESLA-CRPP 1148


 Score = 37.4 bits (85), Expect = 0.036
 Identities = 16/46 (34%), Positives = 27/46 (58%)
 Frame = +1

Query: 112  CPESQPWPCKTPGKCLSFDFICDGEPDCPDKYDEDQSLCTAKNRPP 249
            CP S  + C+   +C+   ++CDG+ DC +  DE  + C+A+  PP
Sbjct: 895  CP-SDRFKCEN-NRCIPNRWLCDGDNDCGNSEDESNATCSARTCPP 938


 Score = 36.6 bits (83), Expect = 0.061
 Identities = 28/72 (38%), Positives = 31/72 (43%), Gaps = 16/72 (22%)
 Frame = +1

Query: 76   TEDKTGTSSGN--GCPESQPWP----CKTPGKCLSFDFICDGEPDCPDKYDE-------- 213
            TED  G  S     CPE +  P    C T G C +  FICDG+ DC D  DE        
Sbjct: 3355 TEDDCGDHSDEPPDCPEFKCRPGQFQCST-GICTNPAFICDGDNDCQDNSDEANCDIHVC 3413

Query: 214  --DQSLCTAKNR 243
               Q  CT  NR
Sbjct: 3414 LPSQFKCTNTNR 3425


 Score = 36.2 bits (82), Expect = 0.080
 Identities = 21/57 (36%), Positives = 32/57 (56%), Gaps = 1/57 (1%)
 Frame = +1

Query: 82   DKTGTSSGNGCPESQPWPCKTPGKCLSFDFICDGEPDCPDKYDEDQSLCTAK-NRPP 249
            D+ G S  + C  +Q + C + G+C+   + CDG+ DC D  DE  + CT +  RPP
Sbjct: 1007 DEAGCS--HSCSSTQ-FKCNS-GRCIPEHWTCDGDNDCGDYSDETHANCTNQATRPP 1059


 Score = 35.8 bits (81), Expect = 0.10
 Identities = 22/61 (36%), Positives = 28/61 (45%)
 Frame = +1

Query: 46  LLYLTIAAFATEDKTGTSSGNGCPESQPWPCKTPGKCLSFDFICDGEPDCPDKYDEDQSL 225
           LL   +AA     KT       C   Q + C+    C+S  + CDGE DCPD  DE   +
Sbjct: 12  LLSALVAAAIDAPKT-------CSPKQ-FACRDQITCISKGWRCDGERDCPDGSDEAPEI 63

Query: 226 C 228
           C
Sbjct: 64  C 64


 Score = 35.0 bits (79), Expect = 0.18
 Identities = 16/48 (33%), Positives = 26/48 (54%)
 Frame = +1

Query: 79   EDKTGTSSGNGCPESQPWPCKTPGKCLSFDFICDGEPDCPDKYDEDQS 222
            ++   T S   CP +Q + C + G+C+   + CD + DC D+ DE  S
Sbjct: 925  DESNATCSARTCPPNQ-FSCAS-GRCIPISWTCDLDDDCGDRSDESAS 970


 Score = 34.3 bits (77), Expect = 0.30
 Identities = 14/35 (40%), Positives = 19/35 (54%)
 Frame = +1

Query: 112  CPESQPWPCKTPGKCLSFDFICDGEPDCPDKYDED 216
            CP ++P+ CK    CL     CDG  +C D  DE+
Sbjct: 3695 CPPNRPFRCKNDRVCLWIGRQCDGTDNCGDGTDEE 3729


 Score = 32.7 bits (73), Expect = 0.88
 Identities = 14/40 (35%), Positives = 20/40 (50%)
 Frame = +1

Query: 94   TSSGNGCPESQPWPCKTPGKCLSFDFICDGEPDCPDKYDE 213
            T    GC  +  + C+  G C+   + CDG+ DC D  DE
Sbjct: 1056 TRPPGGC-HTDEFQCRLDGLCIPLRWRCDGDTDCMDSSDE 1094


 Score = 32.0 bits (71), Expect = 1.5
 Identities = 14/40 (35%), Positives = 23/40 (57%)
 Frame = +1

Query: 94   TSSGNGCPESQPWPCKTPGKCLSFDFICDGEPDCPDKYDE 213
            TS  + C  S  + C + G+C++   +C+G+ DC D  DE
Sbjct: 2898 TSPEHKCNASSQFLCSS-GRCVAEALLCNGQDDCGDSSDE 2936


 Score = 32.0 bits (71), Expect = 1.5
 Identities = 20/52 (38%), Positives = 25/52 (48%)
 Frame = +1

Query: 91   GTSSGNGCPESQPWPCKTPGKCLSFDFICDGEPDCPDKYDEDQSLCTAKNRP 246
            G +  + C  SQ + CK   KC+ F + CD E DC D  DE       K RP
Sbjct: 3327 GRTCVSNCTASQ-FVCKND-KCIPFWWKCDTEDDCGDHSDEPPDCPEFKCRP 3376


 Score = 31.6 bits (70), Expect = 2.0
 Identities = 20/60 (33%), Positives = 27/60 (45%), Gaps = 10/60 (16%)
 Frame = +1

Query: 79   EDKTGTSSGNGC---PESQPWPCKTPG-------KCLSFDFICDGEPDCPDKYDEDQSLC 228
            ED+   + G  C   P   P P   PG       +C+   + CDG+ DC D  DE  +LC
Sbjct: 831  EDQVLDADGVTCLANPSYVPPPQCQPGEFACANSRCIQERWKCDGDNDCLDNSDEAPALC 890


 Score = 31.2 bits (69), Expect = 2.6
 Identities = 14/38 (36%), Positives = 18/38 (47%)
 Frame = +1

Query: 133  PCKTPGKCLSFDFICDGEPDCPDKYDEDQSLCTAKNRP 246
            PC+    C +  ++CDG  DC D  DE    C    RP
Sbjct: 2659 PCERTSLCYAPSWVCDGANDCGDYSDERD--CPGVKRP 2694


 Score = 30.0 bits (66), Expect = 5.7
 Identities = 14/34 (41%), Positives = 21/34 (61%)
 Frame = +1

Query: 112  CPESQPWPCKTPGKCLSFDFICDGEPDCPDKYDE 213
            C E+Q + C+   +C+S  ++CDG  DC D  DE
Sbjct: 2734 CSEAQ-FECQNH-RCISKQWLCDGSDDCGDGSDE 2765


 Score = 29.6 bits (65), Expect = 7.5
 Identities = 16/42 (38%), Positives = 24/42 (57%)
 Frame = +1

Query: 112  CPESQPWPCKTPGKCLSFDFICDGEPDCPDKYDEDQSLCTAK 237
            C ES+ + C   G+C++  + CDG+ DC D  DE    CT +
Sbjct: 3575 CSESE-FSCAN-GRCIAGRWKCDGDHDCADGSDEKD--CTPR 3612


 Score = 29.6 bits (65), Expect = 7.5
 Identities = 13/32 (40%), Positives = 15/32 (46%)
 Frame = +1

Query: 154  CLSFDFICDGEPDCPDKYDEDQSLCTAKNRPP 249
            C    + CDGE DC D  DE+   C     PP
Sbjct: 3666 CKPLAWKCDGEDDCGDNSDENPEECARFVCPP 3697

  Database: Non-redundant SwissProt sequences
    Posted date:  Dec 6, 2005  7:40 AM
  Number of letters in database: 68,354,980
  Number of sequences in database:  184,735
  
  Database: swissprot.01
    Posted date:  Dec 6, 2005  8:18 AM
  Number of letters in database: 66,202,850
  Number of sequences in database:  184,431
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 74,336,313
Number of Sequences: 369166
Number of extensions: 1487356
Number of successful extensions: 5047
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 4426
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5043
length of database: 68,354,980
effective HSP length: 107
effective length of database: 48,588,335
effective search space used: 5636246860
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)

Cluster detail

DrC_00289

  1. Dr_sW_008_A07
  2. Dr_sW_002_F07
  3. Dr_sW_003_J16