Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= DrC_00253 (535 letters) Database: Non-redundant SwissProt sequences 184,735 sequences; 68,354,980 total letters Score E Sequences producing significant alignments: (bits) Value sp|O49923|ADK_PHYPA Adenosine kinase (AK) (Adenosine 5'-pho... 157 2e-38 sp|Q9SF85|ADK1_ARATH Adenosine kinase 1 (AK 1) (Adenosine 5... 155 6e-38 sp|Q9LZG0|ADK2_ARATH Adenosine kinase 2 (AK 2) (Adenosine 5... 151 1e-36 sp|P55264|ADK_MOUSE Adenosine kinase (AK) (Adenosine 5'-pho... 138 7e-33 sp|Q64640|ADK_RAT Adenosine kinase (AK) (Adenosine 5'-phosp... 135 6e-32 sp|P55262|ADK_CRIGR Adenosine kinase (AK) (Adenosine 5'-pho... 132 4e-31 sp|P55263|ADK_HUMAN Adenosine kinase (AK) (Adenosine 5'-pho... 130 2e-30 sp|P78825|ADK_SCHPO Adenosine kinase 113 3e-25 sp|P47143|ADK_YEAST Adenosine kinase 97 3e-20 sp|O93919|ADK_SCHCO Adenosine kinase 95 1e-19
>sp|O49923|ADK_PHYPA Adenosine kinase (AK) (Adenosine 5'-phosphotransferase) Length = 343 Score = 157 bits (396), Expect = 2e-38 Identities = 77/158 (48%), Positives = 103/158 (65%) Frame = +2 Query: 11 KTIKYSV*TSGAEFLVEFFNPQVTEAIEYSNVVFGNEAEATKFAQVKEFGTTDIKEIAIK 190 +T KY + A F+ +FF + E Y + +FGNE+EA FAQV+ + T D K IA+K Sbjct: 184 ETGKYYMINLAAPFICQFFKDPLMELFPYVDFIFGNESEARAFAQVQGWETEDTKVIAVK 243 Query: 191 MSKMPSKIPNKHRTIVITQGADPTIIVHEGEVKLFPINPIQKEKIVDTTGAGDAFVGGFL 370 ++ +P R VITQG DPTI+ +G+V FP+ PI KEK+VDT AGD+FVGGFL Sbjct: 244 LAALPKAGGTHKRVAVITQGTDPTIVAEDGKVTEFPVTPIPKEKLVDTNAAGDSFVGGFL 303 Query: 371 VQLLRGKSLEECVRCANWTAGAIIQQSGCTFPKECCFE 484 QL+ GK + +CVR N+ A IIQ+SGCTFP + FE Sbjct: 304 SQLVLGKDIAQCVRAGNYAASVIIQRSGCTFPSKPSFE 341
>sp|Q9SF85|ADK1_ARATH Adenosine kinase 1 (AK 1) (Adenosine 5'-phosphotransferase 1) Length = 344 Score = 155 bits (392), Expect = 6e-38 Identities = 71/143 (49%), Positives = 101/143 (70%) Frame = +2 Query: 44 AEFLVEFFNPQVTEAIEYSNVVFGNEAEATKFAQVKEFGTTDIKEIAIKMSKMPSKIPNK 223 A F+ EFF + + Y + +FGNE EA F++V + T D+++IAIKMS++P Sbjct: 198 APFICEFFKDVQEKCLPYMDYIFGNETEARTFSRVHGWETDDVEQIAIKMSQLPKASGTY 257 Query: 224 HRTIVITQGADPTIIVHEGEVKLFPINPIQKEKIVDTTGAGDAFVGGFLVQLLRGKSLEE 403 RT VITQGADP ++ +G+VK +P+ P+ KEK+VDT GAGDAFVGGFL QL+ GK +EE Sbjct: 258 KRTTVITQGADPVVVAEDGKVKKYPVIPLPKEKLVDTNGAGDAFVGGFLSQLVHGKGIEE 317 Query: 404 CVRCANWTAGAIIQQSGCTFPKE 472 CVR + + +IQ+SGCT+P++ Sbjct: 318 CVRAGCYASNVVIQRSGCTYPEK 340
>sp|Q9LZG0|ADK2_ARATH Adenosine kinase 2 (AK 2) (Adenosine 5'-phosphotransferase 2) Length = 345 Score = 151 bits (381), Expect = 1e-36 Identities = 69/143 (48%), Positives = 102/143 (71%) Frame = +2 Query: 44 AEFLVEFFNPQVTEAIEYSNVVFGNEAEATKFAQVKEFGTTDIKEIAIKMSKMPSKIPNK 223 A F+ EFF + + Y + VFGNE EA F++V + T D+++IAIK+S++P Sbjct: 199 APFICEFFKDVQEKFLPYMDFVFGNETEARTFSRVHGWETEDVEQIAIKISQLPKATGTY 258 Query: 224 HRTIVITQGADPTIIVHEGEVKLFPINPIQKEKIVDTTGAGDAFVGGFLVQLLRGKSLEE 403 RT VITQGADP ++ +G+VK +P+ P+ KEK+VDT GAGDAFVGGF+ QL++ KS+EE Sbjct: 259 KRTTVITQGADPVVVAEDGKVKKYPVIPLPKEKLVDTNGAGDAFVGGFMSQLVKEKSIEE 318 Query: 404 CVRCANWTAGAIIQQSGCTFPKE 472 CV+ + + +IQ+SGCT+P++ Sbjct: 319 CVKAGCYASNVVIQRSGCTYPEK 341
>sp|P55264|ADK_MOUSE Adenosine kinase (AK) (Adenosine 5'-phosphotransferase) Length = 361 Score = 138 bits (348), Expect = 7e-33 Identities = 65/143 (45%), Positives = 94/143 (65%) Frame = +2 Query: 44 AEFLVEFFNPQVTEAIEYSNVVFGNEAEATKFAQVKEFGTTDIKEIAIKMSKMPSKIPNK 223 A F+ +FF + + + Y +++FGNE EA FA+ + F T DIKEIA K +P + Sbjct: 215 APFISQFFKEALMDVMPYVDILFGNETEAATFAREQGFETKDIKEIAKKAQALPKVNSKR 274 Query: 224 HRTIVITQGADPTIIVHEGEVKLFPINPIQKEKIVDTTGAGDAFVGGFLVQLLRGKSLEE 403 RT++ TQG D TI+ E +V FP+ +E+I+DT GAGDAFVGGFL QL+ K L E Sbjct: 275 QRTVIFTQGRDDTIVAAENDVTAFPVLDQNQEEIIDTNGAGDAFVGGFLSQLVSDKPLTE 334 Query: 404 CVRCANWTAGAIIQQSGCTFPKE 472 C+R ++ A II+++GCTFP++ Sbjct: 335 CIRAGHYAASVIIRRTGCTFPEK 357
>sp|Q64640|ADK_RAT Adenosine kinase (AK) (Adenosine 5'-phosphotransferase) Length = 361 Score = 135 bits (340), Expect = 6e-32 Identities = 65/143 (45%), Positives = 92/143 (64%) Frame = +2 Query: 44 AEFLVEFFNPQVTEAIEYSNVVFGNEAEATKFAQVKEFGTTDIKEIAIKMSKMPSKIPNK 223 A F+ +FF + + Y +++FGNE EA FA+ + F T DIKEIA K +P + Sbjct: 215 APFISQFFKEALMAVMPYVDILFGNETEAATFAREQGFETKDIKEIARKTQALPKVNSKR 274 Query: 224 HRTIVITQGADPTIIVHEGEVKLFPINPIQKEKIVDTTGAGDAFVGGFLVQLLRGKSLEE 403 RT++ TQG D TI+ +V FP+ +E+IVDT GAGDAFVGGFL QL+ K L E Sbjct: 275 QRTVIFTQGRDDTIVATGNDVTAFPVLDQNQEEIVDTNGAGDAFVGGFLSQLVSNKPLTE 334 Query: 404 CVRCANWTAGAIIQQSGCTFPKE 472 C+R ++ A II+++GCTFP++ Sbjct: 335 CIRAGHYAASVIIRRTGCTFPEK 357
>sp|P55262|ADK_CRIGR Adenosine kinase (AK) (Adenosine 5'-phosphotransferase) Length = 361 Score = 132 bits (333), Expect = 4e-31 Identities = 64/143 (44%), Positives = 92/143 (64%) Frame = +2 Query: 44 AEFLVEFFNPQVTEAIEYSNVVFGNEAEATKFAQVKEFGTTDIKEIAIKMSKMPSKIPNK 223 A F+ +FF + E + Y +++FGNE EA FA+ + F T DIKEIA K + + Sbjct: 215 APFISQFFKESLMEVMPYVDILFGNETEAATFAREQGFETKDIKEIAKKAQALAKVNSKR 274 Query: 224 HRTIVITQGADPTIIVHEGEVKLFPINPIQKEKIVDTTGAGDAFVGGFLVQLLRGKSLEE 403 RT+V TQG D T++ E EV F + +++I+DT GAGDAFVGGFL QL+ K L E Sbjct: 275 PRTVVFTQGRDDTVVATENEVMAFAVLDQNQKEIIDTNGAGDAFVGGFLSQLVYNKPLTE 334 Query: 404 CVRCANWTAGAIIQQSGCTFPKE 472 C+R ++ A II+++GCTFP++ Sbjct: 335 CIRAGHYAASVIIRRTGCTFPEK 357
>sp|P55263|ADK_HUMAN Adenosine kinase (AK) (Adenosine 5'-phosphotransferase) Length = 362 Score = 130 bits (328), Expect = 2e-30 Identities = 62/143 (43%), Positives = 92/143 (64%) Frame = +2 Query: 44 AEFLVEFFNPQVTEAIEYSNVVFGNEAEATKFAQVKEFGTTDIKEIAIKMSKMPSKIPNK 223 A F+ +F+ + + + Y +++FGNE EA FA+ + F T DIKEIA K +P + Sbjct: 216 APFISQFYKESLMKVMPYVDILFGNETEAATFAREQGFETKDIKEIAKKTQALPKMNSKR 275 Query: 224 HRTIVITQGADPTIIVHEGEVKLFPINPIQKEKIVDTTGAGDAFVGGFLVQLLRGKSLEE 403 R ++ TQG D TI+ E EV F + +++I+DT GAGDAFVGGFL QL+ K L E Sbjct: 276 QRIVIFTQGRDDTIMATESEVTAFAVLDQDQKEIIDTNGAGDAFVGGFLSQLVSDKPLTE 335 Query: 404 CVRCANWTAGAIIQQSGCTFPKE 472 C+R ++ A II+++GCTFP++ Sbjct: 336 CIRAGHYAASIIIRRTGCTFPEK 358
>sp|P78825|ADK_SCHPO Adenosine kinase Length = 340 Score = 113 bits (282), Expect = 3e-25 Identities = 56/141 (39%), Positives = 82/141 (58%) Frame = +2 Query: 44 AEFLVEFFNPQVTEAIEYSNVVFGNEAEATKFAQVKEFGTTDIKEIAIKMSKMPSKIPNK 223 A FL +FF Q+ I Y + V GNEAE + + +TD++EIA+ +S + + Sbjct: 191 APFLSQFFKEQMDSVIPYCDYVIGNEAEILSYGENHGIKSTDVQEIALALSSVEKVNKKR 250 Query: 224 HRTIVITQGADPTIIVHEGEVKLFPINPIQKEKIVDTTGAGDAFVGGFLVQLLRGKSLEE 403 R +VITQGAD TI+ +G+V + N + E+IVDT GAGDAF GGF+ L +G+ ++ Sbjct: 251 TRVVVITQGADATIVAKDGKVTTYKPNRVPSEEIVDTNGAGDAFAGGFIAALSQGQGIDY 310 Query: 404 CVRCANWTAGAIIQQSGCTFP 466 V +W I+ SG T P Sbjct: 311 AVTLGHWLGQECIKVSGTTLP 331
>sp|P47143|ADK_YEAST Adenosine kinase Length = 340 Score = 96.7 bits (239), Expect = 3e-20 Identities = 49/145 (33%), Positives = 77/145 (53%), Gaps = 2/145 (1%) Frame = +2 Query: 44 AEFLVEFFNPQVTEAIEYSNVVFGNEAEATKFAQVKEF--GTTDIKEIAIKMSKMPSKIP 217 A F+ F + + Y+ V+ NE+EA F + TD++ IA ++ K S + Sbjct: 194 APFIPHVFKDALARVLPYATVIIANESEAEAFCDAFQLDCANTDLEAIAQRIVK-DSPV- 251 Query: 218 NKHRTIVITQGADPTIIVHEGEVKLFPINPIQKEKIVDTTGAGDAFVGGFLVQLLRGKSL 397 +T++ T G +PT++V +P+ P+ KIVDT GAGDAF GGF+ L +G+ L Sbjct: 252 --EKTVIFTHGVEPTVVVSSKGTSTYPVKPLDSSKIVDTNGAGDAFAGGFMAGLTKGEDL 309 Query: 398 EECVRCANWTAGAIIQQSGCTFPKE 472 E + W A IQ+ G ++P E Sbjct: 310 ETSIDMGQWLAALSIQEVGPSYPSE 334
>sp|O93919|ADK_SCHCO Adenosine kinase Length = 344 Score = 94.7 bits (234), Expect = 1e-19 Identities = 50/144 (34%), Positives = 81/144 (56%), Gaps = 4/144 (2%) Frame = +2 Query: 44 AEFLVEFFNPQVTEAIEYSNVVFGNEAEATKFAQVKEF-GTTDIKEIAIKMSKMPSKIPN 220 A F+ +FF P + + + Y ++V NE+EA +A TD+ +A ++ P P Sbjct: 193 APFIPQFFMPAIQQLLPYVDIVIANESEAEAWASASGHPAPTDLAAVAKSLAMQPKTNPA 252 Query: 221 KHRTIVITQGADPTIIVHE---GEVKLFPINPIQKEKIVDTTGAGDAFVGGFLVQLLRGK 391 + R ++ T GA+ T++V+ G V+ F ++ + + +IVDT GAGDAF GGFL L+ G+ Sbjct: 253 RPRVVIFTHGAEETVVVNSAEPGRVRTFKVDKLAEGEIVDTNGAGDAFAGGFLGALVAGR 312 Query: 392 SLEECVRCANWTAGAIIQQSGCTF 463 L++ V + A IQQ G F Sbjct: 313 ELDDSVEAGHKLAKISIQQIGPQF 336
Database: Non-redundant SwissProt sequences Posted date: Dec 6, 2005 7:40 AM Number of letters in database: 68,354,980 Number of sequences in database: 184,735 Database: swissprot.01 Posted date: Dec 6, 2005 8:18 AM Number of letters in database: 66,202,850 Number of sequences in database: 184,431 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 59,012,253 Number of Sequences: 369166 Number of extensions: 1122187 Number of successful extensions: 3128 Number of sequences better than 10.0: 10 Number of HSP's better than 10.0 without gapping: 3052 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 3123 length of database: 68,354,980 effective HSP length: 103 effective length of database: 49,327,275 effective search space used: 3650218350 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)