Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_007_D11
(533 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|O49923|ADK_PHYPA Adenosine kinase (AK) (Adenosine 5'-pho... 157 2e-38
sp|Q9SF85|ADK1_ARATH Adenosine kinase 1 (AK 1) (Adenosine 5... 155 6e-38
sp|Q9LZG0|ADK2_ARATH Adenosine kinase 2 (AK 2) (Adenosine 5... 151 1e-36
sp|P55264|ADK_MOUSE Adenosine kinase (AK) (Adenosine 5'-pho... 138 7e-33
sp|Q64640|ADK_RAT Adenosine kinase (AK) (Adenosine 5'-phosp... 135 6e-32
sp|P55262|ADK_CRIGR Adenosine kinase (AK) (Adenosine 5'-pho... 132 4e-31
sp|P55263|ADK_HUMAN Adenosine kinase (AK) (Adenosine 5'-pho... 130 2e-30
sp|P78825|ADK_SCHPO Adenosine kinase 113 3e-25
sp|P47143|ADK_YEAST Adenosine kinase 97 3e-20
sp|O93919|ADK_SCHCO Adenosine kinase 95 1e-19
>sp|O49923|ADK_PHYPA Adenosine kinase (AK) (Adenosine 5'-phosphotransferase)
Length = 343
Score = 157 bits (396), Expect = 2e-38
Identities = 77/158 (48%), Positives = 103/158 (65%)
Frame = +2
Query: 11 KTIKYSV*TSGAEFLVEFFNPQVTEAIEYSNVVFGNEAEATKFAQVKEFGTTDIKEIAIK 190
+T KY + A F+ +FF + E Y + +FGNE+EA FAQV+ + T D K IA+K
Sbjct: 184 ETGKYYMINLAAPFICQFFKDPLMELFPYVDFIFGNESEARAFAQVQGWETEDTKVIAVK 243
Query: 191 MSKMPSKIPNKHRTIVITQGADPTIIVHEGEVKLFPINPIQKEKIVDTTGAGDAFVGGFL 370
++ +P R VITQG DPTI+ +G+V FP+ PI KEK+VDT AGD+FVGGFL
Sbjct: 244 LAALPKAGGTHKRVAVITQGTDPTIVAEDGKVTEFPVTPIPKEKLVDTNAAGDSFVGGFL 303
Query: 371 VQLLRGKSLEECVRCANWTAGAIIQQSGCTFPKECCFE 484
QL+ GK + +CVR N+ A IIQ+SGCTFP + FE
Sbjct: 304 SQLVLGKDIAQCVRAGNYAASVIIQRSGCTFPSKPSFE 341
>sp|Q9SF85|ADK1_ARATH Adenosine kinase 1 (AK 1) (Adenosine 5'-phosphotransferase 1)
Length = 344
Score = 155 bits (392), Expect = 6e-38
Identities = 71/143 (49%), Positives = 101/143 (70%)
Frame = +2
Query: 44 AEFLVEFFNPQVTEAIEYSNVVFGNEAEATKFAQVKEFGTTDIKEIAIKMSKMPSKIPNK 223
A F+ EFF + + Y + +FGNE EA F++V + T D+++IAIKMS++P
Sbjct: 198 APFICEFFKDVQEKCLPYMDYIFGNETEARTFSRVHGWETDDVEQIAIKMSQLPKASGTY 257
Query: 224 HRTIVITQGADPTIIVHEGEVKLFPINPIQKEKIVDTTGAGDAFVGGFLVQLLRGKSLEE 403
RT VITQGADP ++ +G+VK +P+ P+ KEK+VDT GAGDAFVGGFL QL+ GK +EE
Sbjct: 258 KRTTVITQGADPVVVAEDGKVKKYPVIPLPKEKLVDTNGAGDAFVGGFLSQLVHGKGIEE 317
Query: 404 CVRCANWTAGAIIQQSGCTFPKE 472
CVR + + +IQ+SGCT+P++
Sbjct: 318 CVRAGCYASNVVIQRSGCTYPEK 340
>sp|Q9LZG0|ADK2_ARATH Adenosine kinase 2 (AK 2) (Adenosine 5'-phosphotransferase 2)
Length = 345
Score = 151 bits (381), Expect = 1e-36
Identities = 69/143 (48%), Positives = 102/143 (71%)
Frame = +2
Query: 44 AEFLVEFFNPQVTEAIEYSNVVFGNEAEATKFAQVKEFGTTDIKEIAIKMSKMPSKIPNK 223
A F+ EFF + + Y + VFGNE EA F++V + T D+++IAIK+S++P
Sbjct: 199 APFICEFFKDVQEKFLPYMDFVFGNETEARTFSRVHGWETEDVEQIAIKISQLPKATGTY 258
Query: 224 HRTIVITQGADPTIIVHEGEVKLFPINPIQKEKIVDTTGAGDAFVGGFLVQLLRGKSLEE 403
RT VITQGADP ++ +G+VK +P+ P+ KEK+VDT GAGDAFVGGF+ QL++ KS+EE
Sbjct: 259 KRTTVITQGADPVVVAEDGKVKKYPVIPLPKEKLVDTNGAGDAFVGGFMSQLVKEKSIEE 318
Query: 404 CVRCANWTAGAIIQQSGCTFPKE 472
CV+ + + +IQ+SGCT+P++
Sbjct: 319 CVKAGCYASNVVIQRSGCTYPEK 341
>sp|P55264|ADK_MOUSE Adenosine kinase (AK) (Adenosine 5'-phosphotransferase)
Length = 361
Score = 138 bits (348), Expect = 7e-33
Identities = 65/143 (45%), Positives = 94/143 (65%)
Frame = +2
Query: 44 AEFLVEFFNPQVTEAIEYSNVVFGNEAEATKFAQVKEFGTTDIKEIAIKMSKMPSKIPNK 223
A F+ +FF + + + Y +++FGNE EA FA+ + F T DIKEIA K +P +
Sbjct: 215 APFISQFFKEALMDVMPYVDILFGNETEAATFAREQGFETKDIKEIAKKAQALPKVNSKR 274
Query: 224 HRTIVITQGADPTIIVHEGEVKLFPINPIQKEKIVDTTGAGDAFVGGFLVQLLRGKSLEE 403
RT++ TQG D TI+ E +V FP+ +E+I+DT GAGDAFVGGFL QL+ K L E
Sbjct: 275 QRTVIFTQGRDDTIVAAENDVTAFPVLDQNQEEIIDTNGAGDAFVGGFLSQLVSDKPLTE 334
Query: 404 CVRCANWTAGAIIQQSGCTFPKE 472
C+R ++ A II+++GCTFP++
Sbjct: 335 CIRAGHYAASVIIRRTGCTFPEK 357
>sp|Q64640|ADK_RAT Adenosine kinase (AK) (Adenosine 5'-phosphotransferase)
Length = 361
Score = 135 bits (340), Expect = 6e-32
Identities = 65/143 (45%), Positives = 92/143 (64%)
Frame = +2
Query: 44 AEFLVEFFNPQVTEAIEYSNVVFGNEAEATKFAQVKEFGTTDIKEIAIKMSKMPSKIPNK 223
A F+ +FF + + Y +++FGNE EA FA+ + F T DIKEIA K +P +
Sbjct: 215 APFISQFFKEALMAVMPYVDILFGNETEAATFAREQGFETKDIKEIARKTQALPKVNSKR 274
Query: 224 HRTIVITQGADPTIIVHEGEVKLFPINPIQKEKIVDTTGAGDAFVGGFLVQLLRGKSLEE 403
RT++ TQG D TI+ +V FP+ +E+IVDT GAGDAFVGGFL QL+ K L E
Sbjct: 275 QRTVIFTQGRDDTIVATGNDVTAFPVLDQNQEEIVDTNGAGDAFVGGFLSQLVSNKPLTE 334
Query: 404 CVRCANWTAGAIIQQSGCTFPKE 472
C+R ++ A II+++GCTFP++
Sbjct: 335 CIRAGHYAASVIIRRTGCTFPEK 357
>sp|P55262|ADK_CRIGR Adenosine kinase (AK) (Adenosine 5'-phosphotransferase)
Length = 361
Score = 132 bits (333), Expect = 4e-31
Identities = 64/143 (44%), Positives = 92/143 (64%)
Frame = +2
Query: 44 AEFLVEFFNPQVTEAIEYSNVVFGNEAEATKFAQVKEFGTTDIKEIAIKMSKMPSKIPNK 223
A F+ +FF + E + Y +++FGNE EA FA+ + F T DIKEIA K + +
Sbjct: 215 APFISQFFKESLMEVMPYVDILFGNETEAATFAREQGFETKDIKEIAKKAQALAKVNSKR 274
Query: 224 HRTIVITQGADPTIIVHEGEVKLFPINPIQKEKIVDTTGAGDAFVGGFLVQLLRGKSLEE 403
RT+V TQG D T++ E EV F + +++I+DT GAGDAFVGGFL QL+ K L E
Sbjct: 275 PRTVVFTQGRDDTVVATENEVMAFAVLDQNQKEIIDTNGAGDAFVGGFLSQLVYNKPLTE 334
Query: 404 CVRCANWTAGAIIQQSGCTFPKE 472
C+R ++ A II+++GCTFP++
Sbjct: 335 CIRAGHYAASVIIRRTGCTFPEK 357
>sp|P55263|ADK_HUMAN Adenosine kinase (AK) (Adenosine 5'-phosphotransferase)
Length = 362
Score = 130 bits (328), Expect = 2e-30
Identities = 62/143 (43%), Positives = 92/143 (64%)
Frame = +2
Query: 44 AEFLVEFFNPQVTEAIEYSNVVFGNEAEATKFAQVKEFGTTDIKEIAIKMSKMPSKIPNK 223
A F+ +F+ + + + Y +++FGNE EA FA+ + F T DIKEIA K +P +
Sbjct: 216 APFISQFYKESLMKVMPYVDILFGNETEAATFAREQGFETKDIKEIAKKTQALPKMNSKR 275
Query: 224 HRTIVITQGADPTIIVHEGEVKLFPINPIQKEKIVDTTGAGDAFVGGFLVQLLRGKSLEE 403
R ++ TQG D TI+ E EV F + +++I+DT GAGDAFVGGFL QL+ K L E
Sbjct: 276 QRIVIFTQGRDDTIMATESEVTAFAVLDQDQKEIIDTNGAGDAFVGGFLSQLVSDKPLTE 335
Query: 404 CVRCANWTAGAIIQQSGCTFPKE 472
C+R ++ A II+++GCTFP++
Sbjct: 336 CIRAGHYAASIIIRRTGCTFPEK 358
>sp|P78825|ADK_SCHPO Adenosine kinase
Length = 340
Score = 113 bits (282), Expect = 3e-25
Identities = 56/141 (39%), Positives = 82/141 (58%)
Frame = +2
Query: 44 AEFLVEFFNPQVTEAIEYSNVVFGNEAEATKFAQVKEFGTTDIKEIAIKMSKMPSKIPNK 223
A FL +FF Q+ I Y + V GNEAE + + +TD++EIA+ +S + +
Sbjct: 191 APFLSQFFKEQMDSVIPYCDYVIGNEAEILSYGENHGIKSTDVQEIALALSSVEKVNKKR 250
Query: 224 HRTIVITQGADPTIIVHEGEVKLFPINPIQKEKIVDTTGAGDAFVGGFLVQLLRGKSLEE 403
R +VITQGAD TI+ +G+V + N + E+IVDT GAGDAF GGF+ L +G+ ++
Sbjct: 251 TRVVVITQGADATIVAKDGKVTTYKPNRVPSEEIVDTNGAGDAFAGGFIAALSQGQGIDY 310
Query: 404 CVRCANWTAGAIIQQSGCTFP 466
V +W I+ SG T P
Sbjct: 311 AVTLGHWLGQECIKVSGTTLP 331
>sp|P47143|ADK_YEAST Adenosine kinase
Length = 340
Score = 96.7 bits (239), Expect = 3e-20
Identities = 49/145 (33%), Positives = 77/145 (53%), Gaps = 2/145 (1%)
Frame = +2
Query: 44 AEFLVEFFNPQVTEAIEYSNVVFGNEAEATKFAQVKEF--GTTDIKEIAIKMSKMPSKIP 217
A F+ F + + Y+ V+ NE+EA F + TD++ IA ++ K S +
Sbjct: 194 APFIPHVFKDALARVLPYATVIIANESEAEAFCDAFQLDCANTDLEAIAQRIVK-DSPV- 251
Query: 218 NKHRTIVITQGADPTIIVHEGEVKLFPINPIQKEKIVDTTGAGDAFVGGFLVQLLRGKSL 397
+T++ T G +PT++V +P+ P+ KIVDT GAGDAF GGF+ L +G+ L
Sbjct: 252 --EKTVIFTHGVEPTVVVSSKGTSTYPVKPLDSSKIVDTNGAGDAFAGGFMAGLTKGEDL 309
Query: 398 EECVRCANWTAGAIIQQSGCTFPKE 472
E + W A IQ+ G ++P E
Sbjct: 310 ETSIDMGQWLAALSIQEVGPSYPSE 334
>sp|O93919|ADK_SCHCO Adenosine kinase
Length = 344
Score = 94.7 bits (234), Expect = 1e-19
Identities = 50/144 (34%), Positives = 81/144 (56%), Gaps = 4/144 (2%)
Frame = +2
Query: 44 AEFLVEFFNPQVTEAIEYSNVVFGNEAEATKFAQVKEF-GTTDIKEIAIKMSKMPSKIPN 220
A F+ +FF P + + + Y ++V NE+EA +A TD+ +A ++ P P
Sbjct: 193 APFIPQFFMPAIQQLLPYVDIVIANESEAEAWASASGHPAPTDLAAVAKSLAMQPKTNPA 252
Query: 221 KHRTIVITQGADPTIIVHE---GEVKLFPINPIQKEKIVDTTGAGDAFVGGFLVQLLRGK 391
+ R ++ T GA+ T++V+ G V+ F ++ + + +IVDT GAGDAF GGFL L+ G+
Sbjct: 253 RPRVVIFTHGAEETVVVNSAEPGRVRTFKVDKLAEGEIVDTNGAGDAFAGGFLGALVAGR 312
Query: 392 SLEECVRCANWTAGAIIQQSGCTF 463
L++ V + A IQQ G F
Sbjct: 313 ELDDSVEAGHKLAKISIQQIGPQF 336
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 58,840,409
Number of Sequences: 369166
Number of extensions: 1118706
Number of successful extensions: 3127
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 3051
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3122
length of database: 68,354,980
effective HSP length: 103
effective length of database: 49,327,275
effective search space used: 3650218350
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)