Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= DrC_00167 (943 letters) Database: Non-redundant SwissProt sequences 184,735 sequences; 68,354,980 total letters Score E Sequences producing significant alignments: (bits) Value sp|P33947|ERD22_HUMAN ER lumen protein retaining receptor 2... 315 9e-86 sp|Q9CQM2|ERD22_MOUSE ER lumen protein retaining receptor 2... 315 2e-85 sp|P33946|ERD21_BOVIN ER lumen protein retaining receptor 1... 314 2e-85 sp|Q99JH8|ERD21_MOUSE ER lumen protein retaining receptor 1... 314 3e-85 sp|P24390|ERD21_HUMAN ER lumen protein retaining receptor 1... 314 3e-85 sp|O43731|ERD23_HUMAN ER lumen protein retaining receptor 3... 306 7e-83 sp|O42580|ERD2_XENLA ER lumen protein retaining receptor (K... 305 1e-82 sp|O76767|ERD2_DROME ER lumen protein retaining receptor 300 4e-81 sp|Q8R1L4|ERD23_MOUSE ER lumen protein retaining receptor 3... 298 1e-80 sp|Q09473|ERD22_CAEEL Putative ER lumen protein retaining r... 282 8e-76
>sp|P33947|ERD22_HUMAN ER lumen protein retaining receptor 2 (KDEL receptor 2) (KDEL endoplasmic reticulum protein retention receptor 2) (ERD2-like protein 1) (ELP-1) Length = 212 Score = 315 bits (808), Expect = 9e-86 Identities = 149/211 (70%), Positives = 180/211 (85%) Frame = +3 Query: 15 MNIFRLFGDLSHLGAIIILLLKIWKTRSCAGVSGKTQILFLIVFTARYLDLFTNYVSVYN 194 MNIFRL GDLSHL AI+ILLLKIWKTRSCAG+SGK+Q+LF +VFT RYLDLFT+++S+YN Sbjct: 1 MNIFRLTGDLSHLAAIVILLLKIWKTRSCAGISGKSQLLFALVFTTRYLDLFTSFISLYN 60 Query: 195 TAMKIIYLALISATVYFIYKKFRATFNSEDDTFRIEFILIPTFALAVLENHKSELIEILW 374 T+MK+IYLA ATVY IY KF+AT++ DTFR+EF+++P L+ L NH +EILW Sbjct: 61 TSMKVIYLACSYATVYLIYLKFKATYDGNHDTFRVEFLVVPVGGLSFLVNHDFSPLEILW 120 Query: 375 TFSIYLESLAILPQLFMISKTGSAESITYHYLFALGIYRALYIVNWIYRYYTEGFYDLIA 554 TFSIYLES+AILPQLFMISKTG AE+IT HYLF LG+YRALY+VNWI+R+Y EGF+DLIA Sbjct: 121 TFSIYLESVAILPQLFMISKTGEAETITTHYLFFLGLYRALYLVNWIWRFYFEGFFDLIA 180 Query: 555 IVAGCVQTVFYLDFFYLYATRVLKGKDVILP 647 +VAG VQT+ Y DFFYLY T+VLKGK + LP Sbjct: 181 VVAGVVQTILYCDFFYLYITKVLKGKKLSLP 211
>sp|Q9CQM2|ERD22_MOUSE ER lumen protein retaining receptor 2 (KDEL receptor 2) (KDEL endoplasmic reticulum protein retention receptor 2) sp|Q5U305|ERD22_RAT ER lumen protein retaining receptor 2 (KDEL receptor 2) (KDEL endoplasmic reticulum protein retention receptor 2) Length = 212 Score = 315 bits (806), Expect = 2e-85 Identities = 148/211 (70%), Positives = 180/211 (85%) Frame = +3 Query: 15 MNIFRLFGDLSHLGAIIILLLKIWKTRSCAGVSGKTQILFLIVFTARYLDLFTNYVSVYN 194 MNIFRL GDLSHL AI+ILLLKIWKTRSCAG+SGK+Q+LF +VFT RYLDLFT+++S+YN Sbjct: 1 MNIFRLTGDLSHLAAIVILLLKIWKTRSCAGISGKSQLLFALVFTTRYLDLFTSFISLYN 60 Query: 195 TAMKIIYLALISATVYFIYKKFRATFNSEDDTFRIEFILIPTFALAVLENHKSELIEILW 374 T+MK+IY+A ATVY IY KF+AT++ DTFR+EF+++P L+ L NH +EILW Sbjct: 61 TSMKLIYIACSYATVYLIYMKFKATYDGNHDTFRVEFLVVPVGGLSFLVNHDFSPLEILW 120 Query: 375 TFSIYLESLAILPQLFMISKTGSAESITYHYLFALGIYRALYIVNWIYRYYTEGFYDLIA 554 TFSIYLES+AILPQLFMISKTG AE+IT HYLF LG+YRALY+VNWI+R+Y EGF+DLIA Sbjct: 121 TFSIYLESVAILPQLFMISKTGEAETITTHYLFFLGLYRALYLVNWIWRFYFEGFFDLIA 180 Query: 555 IVAGCVQTVFYLDFFYLYATRVLKGKDVILP 647 +VAG VQT+ Y DFFYLY T+VLKGK + LP Sbjct: 181 VVAGVVQTILYCDFFYLYITKVLKGKKLSLP 211
>sp|P33946|ERD21_BOVIN ER lumen protein retaining receptor 1 (KDEL receptor 1) (KDEL endoplasmic reticulum protein retention receptor 1) Length = 212 Score = 314 bits (805), Expect = 2e-85 Identities = 148/211 (70%), Positives = 178/211 (84%) Frame = +3 Query: 15 MNIFRLFGDLSHLGAIIILLLKIWKTRSCAGVSGKTQILFLIVFTARYLDLFTNYVSVYN 194 MN+FR GDLSHL AII+LLLKIWK+RSCAG+SGK+Q+LF +VFTARYLDLFTNY+S+YN Sbjct: 1 MNLFRFLGDLSHLLAIILLLLKIWKSRSCAGISGKSQVLFAVVFTARYLDLFTNYISLYN 60 Query: 195 TAMKIIYLALISATVYFIYKKFRATFNSEDDTFRIEFILIPTFALAVLENHKSELIEILW 374 T MK++Y+A TV+ IY KF+AT++ DTFR+EF++IPT LA L NH +EILW Sbjct: 61 TCMKVVYIACSFTTVWLIYSKFKATYDGNHDTFRVEFLVIPTAILAFLVNHDFTPLEILW 120 Query: 375 TFSIYLESLAILPQLFMISKTGSAESITYHYLFALGIYRALYIVNWIYRYYTEGFYDLIA 554 TFSIYLES+AILPQLFM+SKTG AE+IT HYLFALG+YR LY+ NWI+RY+ EGF+DLIA Sbjct: 121 TFSIYLESVAILPQLFMVSKTGEAETITSHYLFALGVYRTLYLFNWIWRYHFEGFFDLIA 180 Query: 555 IVAGCVQTVFYLDFFYLYATRVLKGKDVILP 647 IVAG VQTV Y DFFYLY T+VLKGK + LP Sbjct: 181 IVAGLVQTVLYCDFFYLYITKVLKGKKLSLP 211
>sp|Q99JH8|ERD21_MOUSE ER lumen protein retaining receptor 1 (KDEL receptor 1) (KDEL endoplasmic reticulum protein retention receptor 1) Length = 212 Score = 314 bits (804), Expect = 3e-85 Identities = 147/211 (69%), Positives = 178/211 (84%) Frame = +3 Query: 15 MNIFRLFGDLSHLGAIIILLLKIWKTRSCAGVSGKTQILFLIVFTARYLDLFTNYVSVYN 194 MN+FR GDLSHL AII+LLLKIWK+RSCAG+SGK+Q+LF +VFTARYLDLFTNY+S+YN Sbjct: 1 MNLFRFLGDLSHLLAIILLLLKIWKSRSCAGISGKSQVLFAVVFTARYLDLFTNYISLYN 60 Query: 195 TAMKIIYLALISATVYFIYKKFRATFNSEDDTFRIEFILIPTFALAVLENHKSELIEILW 374 T MK++Y+A TV+ IY KF+AT++ DTFR+EF+++PT LA L NH +EILW Sbjct: 61 TCMKVVYIACSFTTVWMIYSKFKATYDGNHDTFRVEFLVVPTAILAFLVNHDFTPLEILW 120 Query: 375 TFSIYLESLAILPQLFMISKTGSAESITYHYLFALGIYRALYIVNWIYRYYTEGFYDLIA 554 TFSIYLES+AILPQLFM+SKTG AE+IT HYLFALG+YR LY+ NWI+RY+ EGF+DLIA Sbjct: 121 TFSIYLESVAILPQLFMVSKTGEAETITSHYLFALGVYRTLYLFNWIWRYHFEGFFDLIA 180 Query: 555 IVAGCVQTVFYLDFFYLYATRVLKGKDVILP 647 IVAG VQTV Y DFFYLY T+VLKGK + LP Sbjct: 181 IVAGLVQTVLYCDFFYLYITKVLKGKKLSLP 211
>sp|P24390|ERD21_HUMAN ER lumen protein retaining receptor 1 (KDEL receptor 1) (KDEL endoplasmic reticulum protein retention receptor 1) Length = 212 Score = 314 bits (804), Expect = 3e-85 Identities = 147/211 (69%), Positives = 178/211 (84%) Frame = +3 Query: 15 MNIFRLFGDLSHLGAIIILLLKIWKTRSCAGVSGKTQILFLIVFTARYLDLFTNYVSVYN 194 MN+FR GDLSHL AII+LLLKIWK+RSCAG+SGK+Q+LF +VFTARYLDLFTNY+S+YN Sbjct: 1 MNLFRFLGDLSHLLAIILLLLKIWKSRSCAGISGKSQVLFAVVFTARYLDLFTNYISLYN 60 Query: 195 TAMKIIYLALISATVYFIYKKFRATFNSEDDTFRIEFILIPTFALAVLENHKSELIEILW 374 T MK++Y+A TV+ IY KF+AT++ DTFR+EF+++PT LA L NH +EILW Sbjct: 61 TCMKVVYIACSFTTVWLIYSKFKATYDGNHDTFRVEFLVVPTAILAFLVNHDFTPLEILW 120 Query: 375 TFSIYLESLAILPQLFMISKTGSAESITYHYLFALGIYRALYIVNWIYRYYTEGFYDLIA 554 TFSIYLES+AILPQLFM+SKTG AE+IT HYLFALG+YR LY+ NWI+RY+ EGF+DLIA Sbjct: 121 TFSIYLESVAILPQLFMVSKTGEAETITSHYLFALGVYRTLYLFNWIWRYHFEGFFDLIA 180 Query: 555 IVAGCVQTVFYLDFFYLYATRVLKGKDVILP 647 IVAG VQTV Y DFFYLY T+VLKGK + LP Sbjct: 181 IVAGLVQTVLYCDFFYLYITKVLKGKKLSLP 211
>sp|O43731|ERD23_HUMAN ER lumen protein retaining receptor 3 (KDEL receptor 3) (KDEL endoplasmic reticulum protein retention receptor 3) Length = 214 Score = 306 bits (783), Expect = 7e-83 Identities = 142/212 (66%), Positives = 176/212 (83%) Frame = +3 Query: 15 MNIFRLFGDLSHLGAIIILLLKIWKTRSCAGVSGKTQILFLIVFTARYLDLFTNYVSVYN 194 MN+FR+ GDLSHL A+I+LL KIW+++ C G+SGK+QILF +VFT RYLDLFTN++S+YN Sbjct: 1 MNVFRILGDLSHLLAMILLLGKIWRSKCCKGISGKSQILFALVFTTRYLDLFTNFISIYN 60 Query: 195 TAMKIIYLALISATVYFIYKKFRATFNSEDDTFRIEFILIPTFALAVLENHKSELIEILW 374 T MK+++L TVY IY KFR TF+SE+DTFR+EF+L+P L+ LEN+ L+EILW Sbjct: 61 TVMKVVFLLCAYVTVYMIYGKFRKTFDSENDTFRLEFLLVPVIGLSFLENYSFTLLEILW 120 Query: 375 TFSIYLESLAILPQLFMISKTGSAESITYHYLFALGIYRALYIVNWIYRYYTEGFYDLIA 554 TFSIYLES+AILPQLFMISKTG AE+IT HYLF LG+YRALY+ NWI RY TE FYD IA Sbjct: 121 TFSIYLESVAILPQLFMISKTGEAETITTHYLFFLGLYRALYLANWIRRYQTENFYDQIA 180 Query: 555 IVAGCVQTVFYLDFFYLYATRVLKGKDVILPV 650 +V+G VQT+FY DFFYLY T+VLKGK + LP+ Sbjct: 181 VVSGVVQTIFYCDFFYLYVTKVLKGKKLSLPM 212
>sp|O42580|ERD2_XENLA ER lumen protein retaining receptor (KDEL receptor) (KDEL endoplasmic reticulum protein retention receptor) Length = 214 Score = 305 bits (781), Expect = 1e-82 Identities = 144/212 (67%), Positives = 178/212 (83%) Frame = +3 Query: 15 MNIFRLFGDLSHLGAIIILLLKIWKTRSCAGVSGKTQILFLIVFTARYLDLFTNYVSVYN 194 MNIFR+ GD+SHL AIIILLLK+WK++SCAG+SGK+Q+LF +VFT RYLDLFT ++S YN Sbjct: 1 MNIFRILGDVSHLLAIIILLLKMWKSKSCAGISGKSQLLFALVFTTRYLDLFTVFISPYN 60 Query: 195 TAMKIIYLALISATVYFIYKKFRATFNSEDDTFRIEFILIPTFALAVLENHKSELIEILW 374 T MKII+LA TVY IY K R +++SE+DTFR+EF+L+P L+ LEN++ +EILW Sbjct: 61 TVMKIIFLACAYVTVYLIYGKLRKSYDSENDTFRLEFLLVPVIGLSFLENYEFTPLEILW 120 Query: 375 TFSIYLESLAILPQLFMISKTGSAESITYHYLFALGIYRALYIVNWIYRYYTEGFYDLIA 554 TFSIYLES+AILPQLFMISKTG AESIT HYLF LG+YR LY+ NWI+RY+TE FYD IA Sbjct: 121 TFSIYLESVAILPQLFMISKTGEAESITTHYLFFLGLYRVLYLANWIWRYHTEKFYDQIA 180 Query: 555 IVAGCVQTVFYLDFFYLYATRVLKGKDVILPV 650 +V+G VQT+FY DFFYLY T+VLKGK + LP+ Sbjct: 181 VVSGVVQTIFYFDFFYLYVTKVLKGKKLSLPM 212
>sp|O76767|ERD2_DROME ER lumen protein retaining receptor Length = 212 Score = 300 bits (768), Expect = 4e-81 Identities = 142/211 (67%), Positives = 175/211 (82%) Frame = +3 Query: 15 MNIFRLFGDLSHLGAIIILLLKIWKTRSCAGVSGKTQILFLIVFTARYLDLFTNYVSVYN 194 MNIFR GDLSH+ AIIILLLKIWKTRSCAG+SGK+QILF +V+ RYLDLFT YVS+YN Sbjct: 1 MNIFRFAGDLSHVFAIIILLLKIWKTRSCAGISGKSQILFAVVYLTRYLDLFTTYVSLYN 60 Query: 195 TAMKIIYLALISATVYFIYKKFRATFNSEDDTFRIEFILIPTFALAVLENHKSELIEILW 374 + MK+++LA ATVY +Y KF+AT++ D+FRIEF+L+P L+++ NH+ ++E+LW Sbjct: 61 SVMKVLFLATSGATVYLMYVKFKATYDHNHDSFRIEFLLVPCALLSLVINHEFTVMEVLW 120 Query: 375 TFSIYLESLAILPQLFMISKTGSAESITYHYLFALGIYRALYIVNWIYRYYTEGFYDLIA 554 TFSIYLES+AILPQLF++S+TG AESIT HYLFALG YRALY++NW+YRY E YDLIA Sbjct: 121 TFSIYLESVAILPQLFLVSRTGEAESITSHYLFALGSYRALYLLNWVYRYMVESHYDLIA 180 Query: 555 IVAGCVQTVFYLDFFYLYATRVLKGKDVILP 647 I AG VQTV Y DFFYLY T+VLKGK + LP Sbjct: 181 IFAGVVQTVLYCDFFYLYITKVLKGKKLQLP 211
>sp|Q8R1L4|ERD23_MOUSE ER lumen protein retaining receptor 3 (KDEL receptor 3) (KDEL endoplasmic reticulum protein retention receptor 3) Length = 214 Score = 298 bits (764), Expect = 1e-80 Identities = 138/212 (65%), Positives = 175/212 (82%) Frame = +3 Query: 15 MNIFRLFGDLSHLGAIIILLLKIWKTRSCAGVSGKTQILFLIVFTARYLDLFTNYVSVYN 194 MN+FR+ GDLSHL A+I+LL+KIW+++SCAG+SGK+QILF +VFT RYLDLF+N++S+YN Sbjct: 1 MNVFRILGDLSHLLAMILLLVKIWRSKSCAGISGKSQILFALVFTTRYLDLFSNFISIYN 60 Query: 195 TAMKIIYLALISATVYFIYKKFRATFNSEDDTFRIEFILIPTFALAVLENHKSELIEILW 374 T MK+++L TVY IY KFR TF+ E+DTFR+EF+L+P L+ L N+ +E+LW Sbjct: 61 TVMKVVFLLCAYVTVYMIYWKFRKTFDIENDTFRLEFLLVPVTGLSFLVNYSYTPMEVLW 120 Query: 375 TFSIYLESLAILPQLFMISKTGSAESITYHYLFALGIYRALYIVNWIYRYYTEGFYDLIA 554 TFSIYLES+AILPQLFMISKTG AE+IT HYLF LG+YR LY+ NWI RY TE FYD I+ Sbjct: 121 TFSIYLESVAILPQLFMISKTGEAETITTHYLFFLGLYRLLYLANWIRRYQTENFYDQIS 180 Query: 555 IVAGCVQTVFYLDFFYLYATRVLKGKDVILPV 650 +V+G VQT+FY DFFYLY T+VLKGK + LPV Sbjct: 181 VVSGVVQTIFYCDFFYLYVTKVLKGKKLSLPV 212
>sp|Q09473|ERD22_CAEEL Putative ER lumen protein retaining receptor C28H8.4 Length = 213 Score = 282 bits (722), Expect = 8e-76 Identities = 137/213 (64%), Positives = 170/213 (79%), Gaps = 1/213 (0%) Frame = +3 Query: 15 MNIFRLFGDLSHLGAIIILLLKIWKTRSCAGVSGKTQILFLIVFTARYLDLFTNYVSVYN 194 MNIFR+ D+SHL AIIILLLKIWK+RSC+G+S ++QILF +VFTARYLDLF+ Y+S+YN Sbjct: 1 MNIFRISADMSHLLAIIILLLKIWKSRSCSGISARSQILFALVFTARYLDLFSTYISLYN 60 Query: 195 TAMKIIYLALISATVYFIYKKFRATFNSEDDTFRIEFILIPTFALAVLENHKSELIEILW 374 T MKI +LA ATVY ++ KFR+T+ E DTFR+E +++P LA+L NH E+LW Sbjct: 61 TTMKITFLAATYATVYLMFFKFRSTYMRESDTFRVELLIVPAAILALLINHDFAPFELLW 120 Query: 375 TFSIYLESLAILPQLFMISKTGSAESITYHYLFALGIYRALYIVNWIYRYYTEGFYDLIA 554 TFSIYLE++AILPQLF++ TGSAE IT HYLFALG YRALYI NWIYRYYTE ++D I Sbjct: 121 TFSIYLEAVAILPQLFLLQSTGSAEVITAHYLFALGSYRALYIFNWIYRYYTEDYFDPIV 180 Query: 555 IVAGCVQTVFYLDFFYLYATRVLK-GKDVILPV 650 +VAG VQTV Y DFFYLY TRV++ K + LP+ Sbjct: 181 VVAGIVQTVLYADFFYLYVTRVVQTRKGMELPI 213
Database: Non-redundant SwissProt sequences Posted date: Dec 6, 2005 7:40 AM Number of letters in database: 68,354,980 Number of sequences in database: 184,735 Database: swissprot.01 Posted date: Dec 6, 2005 8:18 AM Number of letters in database: 66,202,850 Number of sequences in database: 184,431 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 105,925,069 Number of Sequences: 369166 Number of extensions: 2074150 Number of successful extensions: 5479 Number of sequences better than 10.0: 10 Number of HSP's better than 10.0 without gapping: 5261 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 5459 length of database: 68,354,980 effective HSP length: 110 effective length of database: 48,034,130 effective search space used: 9750928390 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)