Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_005_B21
(943 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P33947|ERD22_HUMAN ER lumen protein retaining receptor 2... 315 9e-86
sp|Q9CQM2|ERD22_MOUSE ER lumen protein retaining receptor 2... 315 2e-85
sp|P33946|ERD21_BOVIN ER lumen protein retaining receptor 1... 314 2e-85
sp|Q99JH8|ERD21_MOUSE ER lumen protein retaining receptor 1... 314 3e-85
sp|P24390|ERD21_HUMAN ER lumen protein retaining receptor 1... 314 3e-85
sp|O43731|ERD23_HUMAN ER lumen protein retaining receptor 3... 306 7e-83
sp|O42580|ERD2_XENLA ER lumen protein retaining receptor (K... 305 1e-82
sp|O76767|ERD2_DROME ER lumen protein retaining receptor 300 4e-81
sp|Q8R1L4|ERD23_MOUSE ER lumen protein retaining receptor 3... 298 1e-80
sp|Q09473|ERD22_CAEEL Putative ER lumen protein retaining r... 282 8e-76
>sp|P33947|ERD22_HUMAN ER lumen protein retaining receptor 2 (KDEL receptor 2) (KDEL
endoplasmic reticulum protein retention receptor 2)
(ERD2-like protein 1) (ELP-1)
Length = 212
Score = 315 bits (808), Expect = 9e-86
Identities = 149/211 (70%), Positives = 180/211 (85%)
Frame = +3
Query: 15 MNIFRLFGDLSHLGAIIILLLKIWKTRSCAGVSGKTQILFLIVFTARYLDLFTNYVSVYN 194
MNIFRL GDLSHL AI+ILLLKIWKTRSCAG+SGK+Q+LF +VFT RYLDLFT+++S+YN
Sbjct: 1 MNIFRLTGDLSHLAAIVILLLKIWKTRSCAGISGKSQLLFALVFTTRYLDLFTSFISLYN 60
Query: 195 TAMKIIYLALISATVYFIYKKFRATFNSEDDTFRIEFILIPTFALAVLENHKSELIEILW 374
T+MK+IYLA ATVY IY KF+AT++ DTFR+EF+++P L+ L NH +EILW
Sbjct: 61 TSMKVIYLACSYATVYLIYLKFKATYDGNHDTFRVEFLVVPVGGLSFLVNHDFSPLEILW 120
Query: 375 TFSIYLESLAILPQLFMISKTGSAESITYHYLFALGIYRALYIVNWIYRYYTEGFYDLIA 554
TFSIYLES+AILPQLFMISKTG AE+IT HYLF LG+YRALY+VNWI+R+Y EGF+DLIA
Sbjct: 121 TFSIYLESVAILPQLFMISKTGEAETITTHYLFFLGLYRALYLVNWIWRFYFEGFFDLIA 180
Query: 555 IVAGCVQTVFYLDFFYLYATRVLKGKDVILP 647
+VAG VQT+ Y DFFYLY T+VLKGK + LP
Sbjct: 181 VVAGVVQTILYCDFFYLYITKVLKGKKLSLP 211
>sp|Q9CQM2|ERD22_MOUSE ER lumen protein retaining receptor 2 (KDEL receptor 2) (KDEL
endoplasmic reticulum protein retention receptor 2)
sp|Q5U305|ERD22_RAT ER lumen protein retaining receptor 2 (KDEL receptor 2) (KDEL
endoplasmic reticulum protein retention receptor 2)
Length = 212
Score = 315 bits (806), Expect = 2e-85
Identities = 148/211 (70%), Positives = 180/211 (85%)
Frame = +3
Query: 15 MNIFRLFGDLSHLGAIIILLLKIWKTRSCAGVSGKTQILFLIVFTARYLDLFTNYVSVYN 194
MNIFRL GDLSHL AI+ILLLKIWKTRSCAG+SGK+Q+LF +VFT RYLDLFT+++S+YN
Sbjct: 1 MNIFRLTGDLSHLAAIVILLLKIWKTRSCAGISGKSQLLFALVFTTRYLDLFTSFISLYN 60
Query: 195 TAMKIIYLALISATVYFIYKKFRATFNSEDDTFRIEFILIPTFALAVLENHKSELIEILW 374
T+MK+IY+A ATVY IY KF+AT++ DTFR+EF+++P L+ L NH +EILW
Sbjct: 61 TSMKLIYIACSYATVYLIYMKFKATYDGNHDTFRVEFLVVPVGGLSFLVNHDFSPLEILW 120
Query: 375 TFSIYLESLAILPQLFMISKTGSAESITYHYLFALGIYRALYIVNWIYRYYTEGFYDLIA 554
TFSIYLES+AILPQLFMISKTG AE+IT HYLF LG+YRALY+VNWI+R+Y EGF+DLIA
Sbjct: 121 TFSIYLESVAILPQLFMISKTGEAETITTHYLFFLGLYRALYLVNWIWRFYFEGFFDLIA 180
Query: 555 IVAGCVQTVFYLDFFYLYATRVLKGKDVILP 647
+VAG VQT+ Y DFFYLY T+VLKGK + LP
Sbjct: 181 VVAGVVQTILYCDFFYLYITKVLKGKKLSLP 211
>sp|P33946|ERD21_BOVIN ER lumen protein retaining receptor 1 (KDEL receptor 1) (KDEL
endoplasmic reticulum protein retention receptor 1)
Length = 212
Score = 314 bits (805), Expect = 2e-85
Identities = 148/211 (70%), Positives = 178/211 (84%)
Frame = +3
Query: 15 MNIFRLFGDLSHLGAIIILLLKIWKTRSCAGVSGKTQILFLIVFTARYLDLFTNYVSVYN 194
MN+FR GDLSHL AII+LLLKIWK+RSCAG+SGK+Q+LF +VFTARYLDLFTNY+S+YN
Sbjct: 1 MNLFRFLGDLSHLLAIILLLLKIWKSRSCAGISGKSQVLFAVVFTARYLDLFTNYISLYN 60
Query: 195 TAMKIIYLALISATVYFIYKKFRATFNSEDDTFRIEFILIPTFALAVLENHKSELIEILW 374
T MK++Y+A TV+ IY KF+AT++ DTFR+EF++IPT LA L NH +EILW
Sbjct: 61 TCMKVVYIACSFTTVWLIYSKFKATYDGNHDTFRVEFLVIPTAILAFLVNHDFTPLEILW 120
Query: 375 TFSIYLESLAILPQLFMISKTGSAESITYHYLFALGIYRALYIVNWIYRYYTEGFYDLIA 554
TFSIYLES+AILPQLFM+SKTG AE+IT HYLFALG+YR LY+ NWI+RY+ EGF+DLIA
Sbjct: 121 TFSIYLESVAILPQLFMVSKTGEAETITSHYLFALGVYRTLYLFNWIWRYHFEGFFDLIA 180
Query: 555 IVAGCVQTVFYLDFFYLYATRVLKGKDVILP 647
IVAG VQTV Y DFFYLY T+VLKGK + LP
Sbjct: 181 IVAGLVQTVLYCDFFYLYITKVLKGKKLSLP 211
>sp|Q99JH8|ERD21_MOUSE ER lumen protein retaining receptor 1 (KDEL receptor 1) (KDEL
endoplasmic reticulum protein retention receptor 1)
Length = 212
Score = 314 bits (804), Expect = 3e-85
Identities = 147/211 (69%), Positives = 178/211 (84%)
Frame = +3
Query: 15 MNIFRLFGDLSHLGAIIILLLKIWKTRSCAGVSGKTQILFLIVFTARYLDLFTNYVSVYN 194
MN+FR GDLSHL AII+LLLKIWK+RSCAG+SGK+Q+LF +VFTARYLDLFTNY+S+YN
Sbjct: 1 MNLFRFLGDLSHLLAIILLLLKIWKSRSCAGISGKSQVLFAVVFTARYLDLFTNYISLYN 60
Query: 195 TAMKIIYLALISATVYFIYKKFRATFNSEDDTFRIEFILIPTFALAVLENHKSELIEILW 374
T MK++Y+A TV+ IY KF+AT++ DTFR+EF+++PT LA L NH +EILW
Sbjct: 61 TCMKVVYIACSFTTVWMIYSKFKATYDGNHDTFRVEFLVVPTAILAFLVNHDFTPLEILW 120
Query: 375 TFSIYLESLAILPQLFMISKTGSAESITYHYLFALGIYRALYIVNWIYRYYTEGFYDLIA 554
TFSIYLES+AILPQLFM+SKTG AE+IT HYLFALG+YR LY+ NWI+RY+ EGF+DLIA
Sbjct: 121 TFSIYLESVAILPQLFMVSKTGEAETITSHYLFALGVYRTLYLFNWIWRYHFEGFFDLIA 180
Query: 555 IVAGCVQTVFYLDFFYLYATRVLKGKDVILP 647
IVAG VQTV Y DFFYLY T+VLKGK + LP
Sbjct: 181 IVAGLVQTVLYCDFFYLYITKVLKGKKLSLP 211
>sp|P24390|ERD21_HUMAN ER lumen protein retaining receptor 1 (KDEL receptor 1) (KDEL
endoplasmic reticulum protein retention receptor 1)
Length = 212
Score = 314 bits (804), Expect = 3e-85
Identities = 147/211 (69%), Positives = 178/211 (84%)
Frame = +3
Query: 15 MNIFRLFGDLSHLGAIIILLLKIWKTRSCAGVSGKTQILFLIVFTARYLDLFTNYVSVYN 194
MN+FR GDLSHL AII+LLLKIWK+RSCAG+SGK+Q+LF +VFTARYLDLFTNY+S+YN
Sbjct: 1 MNLFRFLGDLSHLLAIILLLLKIWKSRSCAGISGKSQVLFAVVFTARYLDLFTNYISLYN 60
Query: 195 TAMKIIYLALISATVYFIYKKFRATFNSEDDTFRIEFILIPTFALAVLENHKSELIEILW 374
T MK++Y+A TV+ IY KF+AT++ DTFR+EF+++PT LA L NH +EILW
Sbjct: 61 TCMKVVYIACSFTTVWLIYSKFKATYDGNHDTFRVEFLVVPTAILAFLVNHDFTPLEILW 120
Query: 375 TFSIYLESLAILPQLFMISKTGSAESITYHYLFALGIYRALYIVNWIYRYYTEGFYDLIA 554
TFSIYLES+AILPQLFM+SKTG AE+IT HYLFALG+YR LY+ NWI+RY+ EGF+DLIA
Sbjct: 121 TFSIYLESVAILPQLFMVSKTGEAETITSHYLFALGVYRTLYLFNWIWRYHFEGFFDLIA 180
Query: 555 IVAGCVQTVFYLDFFYLYATRVLKGKDVILP 647
IVAG VQTV Y DFFYLY T+VLKGK + LP
Sbjct: 181 IVAGLVQTVLYCDFFYLYITKVLKGKKLSLP 211
>sp|O43731|ERD23_HUMAN ER lumen protein retaining receptor 3 (KDEL receptor 3) (KDEL
endoplasmic reticulum protein retention receptor 3)
Length = 214
Score = 306 bits (783), Expect = 7e-83
Identities = 142/212 (66%), Positives = 176/212 (83%)
Frame = +3
Query: 15 MNIFRLFGDLSHLGAIIILLLKIWKTRSCAGVSGKTQILFLIVFTARYLDLFTNYVSVYN 194
MN+FR+ GDLSHL A+I+LL KIW+++ C G+SGK+QILF +VFT RYLDLFTN++S+YN
Sbjct: 1 MNVFRILGDLSHLLAMILLLGKIWRSKCCKGISGKSQILFALVFTTRYLDLFTNFISIYN 60
Query: 195 TAMKIIYLALISATVYFIYKKFRATFNSEDDTFRIEFILIPTFALAVLENHKSELIEILW 374
T MK+++L TVY IY KFR TF+SE+DTFR+EF+L+P L+ LEN+ L+EILW
Sbjct: 61 TVMKVVFLLCAYVTVYMIYGKFRKTFDSENDTFRLEFLLVPVIGLSFLENYSFTLLEILW 120
Query: 375 TFSIYLESLAILPQLFMISKTGSAESITYHYLFALGIYRALYIVNWIYRYYTEGFYDLIA 554
TFSIYLES+AILPQLFMISKTG AE+IT HYLF LG+YRALY+ NWI RY TE FYD IA
Sbjct: 121 TFSIYLESVAILPQLFMISKTGEAETITTHYLFFLGLYRALYLANWIRRYQTENFYDQIA 180
Query: 555 IVAGCVQTVFYLDFFYLYATRVLKGKDVILPV 650
+V+G VQT+FY DFFYLY T+VLKGK + LP+
Sbjct: 181 VVSGVVQTIFYCDFFYLYVTKVLKGKKLSLPM 212
>sp|O42580|ERD2_XENLA ER lumen protein retaining receptor (KDEL receptor) (KDEL
endoplasmic reticulum protein retention receptor)
Length = 214
Score = 305 bits (781), Expect = 1e-82
Identities = 144/212 (67%), Positives = 178/212 (83%)
Frame = +3
Query: 15 MNIFRLFGDLSHLGAIIILLLKIWKTRSCAGVSGKTQILFLIVFTARYLDLFTNYVSVYN 194
MNIFR+ GD+SHL AIIILLLK+WK++SCAG+SGK+Q+LF +VFT RYLDLFT ++S YN
Sbjct: 1 MNIFRILGDVSHLLAIIILLLKMWKSKSCAGISGKSQLLFALVFTTRYLDLFTVFISPYN 60
Query: 195 TAMKIIYLALISATVYFIYKKFRATFNSEDDTFRIEFILIPTFALAVLENHKSELIEILW 374
T MKII+LA TVY IY K R +++SE+DTFR+EF+L+P L+ LEN++ +EILW
Sbjct: 61 TVMKIIFLACAYVTVYLIYGKLRKSYDSENDTFRLEFLLVPVIGLSFLENYEFTPLEILW 120
Query: 375 TFSIYLESLAILPQLFMISKTGSAESITYHYLFALGIYRALYIVNWIYRYYTEGFYDLIA 554
TFSIYLES+AILPQLFMISKTG AESIT HYLF LG+YR LY+ NWI+RY+TE FYD IA
Sbjct: 121 TFSIYLESVAILPQLFMISKTGEAESITTHYLFFLGLYRVLYLANWIWRYHTEKFYDQIA 180
Query: 555 IVAGCVQTVFYLDFFYLYATRVLKGKDVILPV 650
+V+G VQT+FY DFFYLY T+VLKGK + LP+
Sbjct: 181 VVSGVVQTIFYFDFFYLYVTKVLKGKKLSLPM 212
>sp|O76767|ERD2_DROME ER lumen protein retaining receptor
Length = 212
Score = 300 bits (768), Expect = 4e-81
Identities = 142/211 (67%), Positives = 175/211 (82%)
Frame = +3
Query: 15 MNIFRLFGDLSHLGAIIILLLKIWKTRSCAGVSGKTQILFLIVFTARYLDLFTNYVSVYN 194
MNIFR GDLSH+ AIIILLLKIWKTRSCAG+SGK+QILF +V+ RYLDLFT YVS+YN
Sbjct: 1 MNIFRFAGDLSHVFAIIILLLKIWKTRSCAGISGKSQILFAVVYLTRYLDLFTTYVSLYN 60
Query: 195 TAMKIIYLALISATVYFIYKKFRATFNSEDDTFRIEFILIPTFALAVLENHKSELIEILW 374
+ MK+++LA ATVY +Y KF+AT++ D+FRIEF+L+P L+++ NH+ ++E+LW
Sbjct: 61 SVMKVLFLATSGATVYLMYVKFKATYDHNHDSFRIEFLLVPCALLSLVINHEFTVMEVLW 120
Query: 375 TFSIYLESLAILPQLFMISKTGSAESITYHYLFALGIYRALYIVNWIYRYYTEGFYDLIA 554
TFSIYLES+AILPQLF++S+TG AESIT HYLFALG YRALY++NW+YRY E YDLIA
Sbjct: 121 TFSIYLESVAILPQLFLVSRTGEAESITSHYLFALGSYRALYLLNWVYRYMVESHYDLIA 180
Query: 555 IVAGCVQTVFYLDFFYLYATRVLKGKDVILP 647
I AG VQTV Y DFFYLY T+VLKGK + LP
Sbjct: 181 IFAGVVQTVLYCDFFYLYITKVLKGKKLQLP 211
>sp|Q8R1L4|ERD23_MOUSE ER lumen protein retaining receptor 3 (KDEL receptor 3) (KDEL
endoplasmic reticulum protein retention receptor 3)
Length = 214
Score = 298 bits (764), Expect = 1e-80
Identities = 138/212 (65%), Positives = 175/212 (82%)
Frame = +3
Query: 15 MNIFRLFGDLSHLGAIIILLLKIWKTRSCAGVSGKTQILFLIVFTARYLDLFTNYVSVYN 194
MN+FR+ GDLSHL A+I+LL+KIW+++SCAG+SGK+QILF +VFT RYLDLF+N++S+YN
Sbjct: 1 MNVFRILGDLSHLLAMILLLVKIWRSKSCAGISGKSQILFALVFTTRYLDLFSNFISIYN 60
Query: 195 TAMKIIYLALISATVYFIYKKFRATFNSEDDTFRIEFILIPTFALAVLENHKSELIEILW 374
T MK+++L TVY IY KFR TF+ E+DTFR+EF+L+P L+ L N+ +E+LW
Sbjct: 61 TVMKVVFLLCAYVTVYMIYWKFRKTFDIENDTFRLEFLLVPVTGLSFLVNYSYTPMEVLW 120
Query: 375 TFSIYLESLAILPQLFMISKTGSAESITYHYLFALGIYRALYIVNWIYRYYTEGFYDLIA 554
TFSIYLES+AILPQLFMISKTG AE+IT HYLF LG+YR LY+ NWI RY TE FYD I+
Sbjct: 121 TFSIYLESVAILPQLFMISKTGEAETITTHYLFFLGLYRLLYLANWIRRYQTENFYDQIS 180
Query: 555 IVAGCVQTVFYLDFFYLYATRVLKGKDVILPV 650
+V+G VQT+FY DFFYLY T+VLKGK + LPV
Sbjct: 181 VVSGVVQTIFYCDFFYLYVTKVLKGKKLSLPV 212
>sp|Q09473|ERD22_CAEEL Putative ER lumen protein retaining receptor C28H8.4
Length = 213
Score = 282 bits (722), Expect = 8e-76
Identities = 137/213 (64%), Positives = 170/213 (79%), Gaps = 1/213 (0%)
Frame = +3
Query: 15 MNIFRLFGDLSHLGAIIILLLKIWKTRSCAGVSGKTQILFLIVFTARYLDLFTNYVSVYN 194
MNIFR+ D+SHL AIIILLLKIWK+RSC+G+S ++QILF +VFTARYLDLF+ Y+S+YN
Sbjct: 1 MNIFRISADMSHLLAIIILLLKIWKSRSCSGISARSQILFALVFTARYLDLFSTYISLYN 60
Query: 195 TAMKIIYLALISATVYFIYKKFRATFNSEDDTFRIEFILIPTFALAVLENHKSELIEILW 374
T MKI +LA ATVY ++ KFR+T+ E DTFR+E +++P LA+L NH E+LW
Sbjct: 61 TTMKITFLAATYATVYLMFFKFRSTYMRESDTFRVELLIVPAAILALLINHDFAPFELLW 120
Query: 375 TFSIYLESLAILPQLFMISKTGSAESITYHYLFALGIYRALYIVNWIYRYYTEGFYDLIA 554
TFSIYLE++AILPQLF++ TGSAE IT HYLFALG YRALYI NWIYRYYTE ++D I
Sbjct: 121 TFSIYLEAVAILPQLFLLQSTGSAEVITAHYLFALGSYRALYIFNWIYRYYTEDYFDPIV 180
Query: 555 IVAGCVQTVFYLDFFYLYATRVLK-GKDVILPV 650
+VAG VQTV Y DFFYLY TRV++ K + LP+
Sbjct: 181 VVAGIVQTVLYADFFYLYVTRVVQTRKGMELPI 213
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 105,553,063
Number of Sequences: 369166
Number of extensions: 2067466
Number of successful extensions: 5433
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 5221
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5413
length of database: 68,354,980
effective HSP length: 110
effective length of database: 48,034,130
effective search space used: 9750928390
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)