Planaria EST Database

DrC_00074

BLASTX 2.2.13 [Nov-27-2005]

Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= DrC_00074
         (1371 letters)

Database: Non-redundant SwissProt sequences 
           184,735 sequences; 68,354,980 total letters



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

sp|Q96PZ0|Y1897_HUMAN  Hypothetical pseudouridine synthase K...   280   5e-75
sp|Q08647|YO7T_YEAST  Hypothetical pseudouridine synthase YO...   220   7e-57
sp|O74343|YH2X_SCHPO  Hypothetical pseudouridine synthase C1...   211   3e-54
sp|Q17426|YQ4B_CAEEL  Hypothetical pseudouridine synthase in...   155   2e-37
sp|Q6L1R2|TRUD_PICTO  Probable tRNA pseudouridine synthase D...   119   2e-26
sp|O28596|TRUD_ARCFU  Probable tRNA pseudouridine synthase D...   117   8e-26
sp|Q9HLL3|TRUD_THEAC  Probable tRNA pseudouridine synthase D...   115   2e-25
sp|Q978K9|TRUD_THEVO  Probable tRNA pseudouridine synthase D...   111   6e-24
sp|Q8TKX2|TRUD_METAC  Probable tRNA pseudouridine synthase D...   110   1e-23
sp|Q58008|TRUD1_METJA  Probable tRNA pseudouridine synthase ...   108   4e-23

>sp|Q96PZ0|Y1897_HUMAN Hypothetical pseudouridine synthase KIAA1897
          Length = 661

 Score =  280 bits (717), Expect = 5e-75
 Identities = 165/435 (37%), Positives = 261/435 (60%), Gaps = 12/435 (2%)
 Frame = +2

Query: 101  EVGIEEFFDNIGVGFSGKIKERWEDFIVNEVDLNNHVVFLENTDLPLPKCVNNNIENRHL 280
            +VGI +F  +   GFSG +KER+ DF+V+E+  +  +  L +  +P+ +   +      L
Sbjct: 113  DVGITKFVSS-HQGFSGILKERYSDFVVHEIGKDGRISHLNDLSIPVDEEDPSEDIFTVL 171

Query: 281  NESVINDLENLSAISCKKE--VIFDAPDDKLIRTDIYNFLKSNYPNLYGNTELKDGKRVF 454
                   LE L     K+    I    D K  RT I+  +KS +P L   TE ++GK+ +
Sbjct: 172  TAEEKQRLEELQLFKNKETSVAIEVIEDTKEKRTIIHQAIKSLFPGLETKTEDREGKK-Y 230

Query: 455  IVTNYEDERSQIA--KKISKTSGDDDYCQFVLYKEGKDTISAISLIAKYLKMKPGSFTYA 628
            IV  +   +  +A  +K S       YC FVLYKE KDT+ AI++++KYL++KP  F+Y 
Sbjct: 231  IVAYHAAGKKALANPRKHSWPKSRGSYCHFVLYKENKDTMDAINVLSKYLRVKPNIFSYM 290

Query: 629  GTKDRRGITSQLVRIRSCAANRLKGLNKCLNGIVLGNFSYHHSPLKLGDLYGNRFRLVIR 808
            GTKD+R IT Q + +    A RL  LNKCL    LGNFSY  +PLKLG+L GN F +V+R
Sbjct: 291  GTKDKRAITVQEIAVLKITAQRLAHLNKCLMNFKLGNFSYQKNPLKLGELQGNHFTVVLR 350

Query: 809  DVHGSDKDIEAAIDRFKK-GFINYFGMQRFGSTEIRSHEIGKLAIASKWEDMIKLILEP- 982
            ++ G+D  ++ A++  K+ GFINY+GMQRFG+T + ++++G+  + + W +++ LIL+P 
Sbjct: 351  NITGTDDQVQQAMNSLKEIGFINYYGMQRFGTTAVPTYQVGRAILQNSWTEVMDLILKPR 410

Query: 983  TPQDLPFMRECKMKFKENQNIDEFLK----ASCNGIERSLVSGISKHGY--ILNAIDTLP 1144
            +  +  ++ +C+ ++ + ++    L+      C  +E  L+ G+SK+G   I++A   +P
Sbjct: 411  SGAEKGYLVKCREEWAKTKDPTAALRKLPVKRC--VEGQLLRGLSKYGMKNIVSAFGIIP 468

Query: 1145 RNLKQLYVHSYQSYVWNKIASMRIRECGNSAVMAGDLIEIGDQQVIVVDEADVNKYTIGD 1324
            RN + +Y+HSYQSYVWN + S RI + G   V  GDL+  G      ++E DVN Y+I D
Sbjct: 469  RNNRLMYIHSYQSYVWNNMVSKRIEDYGLKPV-PGDLVLKG-ATATYIEEDDVNNYSIHD 526

Query: 1325 VVLPLPGYDVKLPEN 1369
            VV+PLPG+DV  P++
Sbjct: 527  VVMPLPGFDVIYPKH 541

>sp|Q08647|YO7T_YEAST Hypothetical pseudouridine synthase YOR243C
          Length = 676

 Score =  220 bits (561), Expect = 7e-57
 Identities = 160/524 (30%), Positives = 246/524 (46%), Gaps = 80/524 (15%)
 Frame = +2

Query: 38   EPPRKRLCVENSSVSCNNRYIEVGIEEFFDNIGVGFSGKIKERWEDFIVNEVDLNNHVVF 217
            E   K+L +E  + +      +VGI  F      GF G+IK+R+ DF+VNE+D    V+ 
Sbjct: 21   ENAAKKLKIEQRTQADGIHEADVGITLFLSPELPGFRGQIKQRYTDFLVNEIDQEGKVIH 80

Query: 218  LENTDLPLPKCVNNNIENRH--------------------------LNESVINDLENLSA 319
            L +    +PK    + E  +                            E  +  +E++  
Sbjct: 81   LTDKGFKMPKKPQRSKEEVNAEKESEAARRQEFNVDPELRNQLVEIFGEEDVLKIESVYR 140

Query: 320  ISCKKEVIFDAPDDKLIRTDIYNFLKSNYPNLYGNTELKDGKRVFIVTNYEDERSQIAKK 499
             + K E   +  +DK +RT I+  L+  + N   +    D     I  +  + R+   +K
Sbjct: 141  TANKMETAKNF-EDKSVRTKIHQLLREAFKNELESVTT-DTNTFKIARSNRNSRTNKQEK 198

Query: 500  ISKTSGDD-----------DYCQFVLYKEGKDTISAISLIAKYLKMKPGSFTYAGTKDRR 646
            I++T   +           D+  F L+KE KDT+ A+++I K L++      YAGTKDRR
Sbjct: 199  INQTRDANGVENWGYGPSKDFIHFTLHKENKDTMEAVNVITKLLRVPSRVIRYAGTKDRR 258

Query: 647  GITSQLVRIRSCAANRLKGLNKCLNGIVLGNFSYHHSPLKLGDLYGNRFRLVIRDV--HG 820
             +T Q V I     +RL  LN+ L G+++GN+++  + L LGDL GN F +VIRDV    
Sbjct: 259  AVTCQRVSISKIGLDRLNALNRTLKGMIIGNYNFSDASLNLGDLKGNEFVVVIRDVTTGN 318

Query: 821  SDKDIEAAIDR-----FKKGFINYFGMQRFGSTEIRSHEIGKLAIASKWEDMIKLILEPT 985
            S+  +E  +        + GFINYFGMQRFG+  I +H IG+  + S W+   +LIL   
Sbjct: 319  SEVSLEEIVSNGCKSLSENGFINYFGMQRFGTFSISTHTIGRELLLSNWKKAAELILSDQ 378

Query: 986  PQDLPFMRECKMKFKENQNIDEFLK---ASC---NGI------ERSLVSGISKHGYILNA 1129
               LP  +E +  + E ++    LK     C   N +      +R    G         A
Sbjct: 379  DNVLPKSKEARKIWAETKDAALALKQMPRQCLAENALLYSLSNQRKEEDGTYSENAYYTA 438

Query: 1130 IDTLPRNLKQLYVHSYQSYVWNKIASMRIRECGNSAVMAGDLIEIGDQQVIV--VDEADV 1303
            I  +PRNL+ +YVH+YQSYVWN IAS RI   G   V+   +I+  ++  ++  +D+ D 
Sbjct: 439  IMKIPRNLRTMYVHAYQSYVWNSIASKRIELHGLKLVVGDLVIDTSEKSPLISGIDDEDF 498

Query: 1304 N----------------------KYTIGDVVLPLPGYDVKLPEN 1369
            +                      KYT+ DVVLP PG+DV  P N
Sbjct: 499  DEDVREAQFIRAKAVTQEDIDSVKYTMEDVVLPSPGFDVLYPSN 542

>sp|O74343|YH2X_SCHPO Hypothetical pseudouridine synthase C1A4.09 in chromosome II
          Length = 680

 Score =  211 bits (538), Expect = 3e-54
 Identities = 158/508 (31%), Positives = 245/508 (48%), Gaps = 85/508 (16%)
 Frame = +2

Query: 101  EVGIEEFFDNIGVGFSGKIKERWEDFIVNEVDLNNHVVFL---ENTDLPLPKCV------ 253
            +VGI+ F +       G IK R+ DF V EVD + ++V L   E  D  L K        
Sbjct: 51   DVGIDAFLNPNLPSIDGIIKARFTDFAVFEVDTDGNIVHLTDMEAHDPILSKATGDKETE 110

Query: 254  ------NNNIENRHLNES-----------VINDLENLSAISCKKEVIFDA---------- 352
                  N +I N     S           + NDL+++       E I             
Sbjct: 111  DAKDSSNQDISNDQKAPSFKEQEPATLPILPNDLQSIIPKGIGNEFIQSLHKLSVGEITD 170

Query: 353  -----------PDDKLIRTDIYNFLKSNYPNLYGNTELKDGKRVFIVTNYEDERSQIAKK 499
                       P DK  RT ++ F+++N+  L  +T+      V   T     RS+   +
Sbjct: 171  PISLILPENTPPMDKGQRTILHQFIRNNFSGLESSTKGNGTFTVSKTTRKNQPRSRRDPR 230

Query: 500  ISKTSGDDDYCQFVLYKEGKDTISAISLIAKYLKMKPGSFTYAGTKDRRGITSQLVRIRS 679
            +S  +   +YC F LYKE +D++  +  IA+ LK+   + + AGTKDRRG+T Q V I  
Sbjct: 231  LSWKALGGEYCHFHLYKENRDSMDCLGKIARLLKVPTRTLSIAGTKDRRGVTCQRVAIHH 290

Query: 680  CAANRLKGLN-----KCLNGIVLGNFSYHHSPLKLGDLYGNRFRLVIRDVHGSDKDIEAA 844
              A+RL  LN         G +LGN+SY +S L+LGDL GN F +V+R+V    + +  A
Sbjct: 291  VRASRLAQLNSGSLKNSTYGFLLGNYSYKNSNLRLGDLKGNEFHIVVRNVITPKEKVVEA 350

Query: 845  IDRFKK-GFINYFGMQRFGSTEIRSHEIGKLAIASKWEDMIKLILEPTPQDLPFMRECKM 1021
            ++  K+ GFINYFG+QRFG++ + +H IG   + S W+  + LIL P P+    ++E   
Sbjct: 351  LNSLKEHGFINYFGLQRFGTSSVGTHTIGVRLLQSDWKGAVDLILSPRPEHTGSVKEAID 410

Query: 1022 KFKENQNIDEFLKASCNGI--ERSLVSGISKHGY---ILNAIDTLPRNLKQLYVHSYQSY 1186
             +    + +  L+     +  E S++   S+ G     L A   +PR+L+ +Y H+YQSY
Sbjct: 411  LWHSTHDAEASLRILPRRMIAESSILETWSRSGNQTDYLGAFQRIPRHLRSIYPHAYQSY 470

Query: 1187 VWNKIASMRIRECGNSAVMAGDLI------EIGDQQVIV--------------------- 1285
            VWN++AS RI+  G+  V+ GDL+       +  +  IV                     
Sbjct: 471  VWNRVASWRIKNLGDRPVV-GDLVYSTESNGLSQKSPIVDPEAPDLLEDLPVSSKLSARP 529

Query: 1286 VDEADVNKYTIGDVVLPLPGYDVKLPEN 1369
            ++E +VN ++I D+VLPLPG +V  P+N
Sbjct: 530  IEEDEVNNFSIYDIVLPLPGRNVIYPKN 557

>sp|Q17426|YQ4B_CAEEL Hypothetical pseudouridine synthase in chromosome V
          Length = 577

 Score =  155 bits (393), Expect = 2e-37
 Identities = 123/426 (28%), Positives = 207/426 (48%), Gaps = 29/426 (6%)
 Frame = +2

Query: 155  IKERWEDFIVNEVDLNNHVVFLENTDLPLPKCVNNNIENRHLNESVIN----DLENLSAI 322
            +KE + DFIV E+  ++ V+ + + D+ L +   +  E+  + E V        E L+A+
Sbjct: 23   LKEMYSDFIVQEILADHTVLAIPSPDVVL-ESTGSKKEDIEIEECVAKPDCISEETLAAL 81

Query: 323  ----SCKKEVIFDAPDD--KLIRTDIYNFLKSNYPNLYGNTELKDGKRVFIVTNYEDERS 484
                S K + +    DD  K  R  I++F++  Y  +      +DG    I+ ++   +S
Sbjct: 82   NDRFSTKGDPVLVKVDDLSKEDRKSIHHFIRERYAGVLITETKEDG----ILVSHGHTKS 137

Query: 485  QIAKKISKTSGDDDYCQFVLYKEGKDTISAISLIAKYLKMKPGSFTYAGTKDRRGITSQL 664
               +K+       + C F + KE K+T  A  LIAK+L + P +    G KD+R +TSQ 
Sbjct: 138  SRKRKLWDEKVPKE-CHFTICKENKETSFACQLIAKFLNVGPNNIRTHGIKDKRAVTSQR 196

Query: 665  VRIRSCAANRLKGLNKCLNGIVLGNFSYHHSPLKLGDLYGNRFRLVIRDV-HGSDKDIEA 841
            V +       +  LN  L GI +    Y   P+++G  +GNRF +V+R +   S++ +  
Sbjct: 197  VSVTKVHERTILDLNSKLRGIRVFGCEYKDDPVQMGAHWGNRFSIVLRSLPDDSEQLLHQ 256

Query: 842  AIDRFKK-GFINYFGMQRFGSTEIRSHEIGKLAIASKWEDMIKLILEPTPQD------LP 1000
             ++ F+  GFINYFG QRFGS    + EIG   +   WE  +K+I+     D      + 
Sbjct: 257  RLETFQNTGFINYFGTQRFGSRSSTTAEIGLAIVKRDWEKAVKMIMTNAMPDHLGYGSVG 316

Query: 1001 FMRECKMKFKENQNIDEFLKA--SCNGIERSLVSGISKHGYILNAI-DTLPRNLKQLYVH 1171
            +  +C  +  + +     LK   +   +E +++  +SK G   N I + +P   + LYVH
Sbjct: 317  YAAKCFSQTGDARKAFSKLKGAQAFATVEGNILKCLSKGGTWQNCITEAIPIQSRSLYVH 376

Query: 1172 SYQSYVWNKIASMRIRECGNSAVMAGDLIEIGDQQVIVVDEADV--NKYTIG------DV 1327
            +YQS +WNK+AS R++E G                   V E+DV  N +++G      D+
Sbjct: 377  AYQSLIWNKVASRRVKEYGTR-----------------VHESDVGANGFSLGEHATHYDI 419

Query: 1328 VLPLPG 1345
             +PLPG
Sbjct: 420  HIPLPG 425

>sp|Q6L1R2|TRUD_PICTO Probable tRNA pseudouridine synthase D (tRNA-uridine isomerase D)
            (tRNA pseudouridylate synthase D)
          Length = 414

 Score =  119 bits (298), Expect = 2e-26
 Identities = 97/339 (28%), Positives = 165/339 (48%), Gaps = 21/339 (6%)
 Frame = +2

Query: 413  LYGNTELKDGKRVFIVTNYEDERSQIAKKISKTSGDDDYCQFVLYKEGK---DTISAISL 583
            +YG     +     I +N ED    I ++I      DD  ++++ K      DT   +  
Sbjct: 15   MYGYITKTEKLNGMIKSNPEDF---IVEEIPFDIKKDDNGKYLIIKARLYDWDTNRFVMY 71

Query: 584  IAKYLKMKPGSFTYAGTKDRRGITSQLVRIRSCAANRLKGLNKCLNGIVLGNFSYHHSPL 763
            +A+++ +     TYAGTKD+R +T+Q   I     N  +  +  +NGI +      +  +
Sbjct: 72   LARHMNISRKRITYAGTKDKRAVTTQYFCI-----NTDRMFSGSINGIEIIEQFRSNDII 126

Query: 764  KLGDLYGNRFRLVIRDVHGSDKDIEAAIDRF--KKGFINYFGMQRFGSTEIRSHEIGKLA 937
            KLGDLYGNRF + +      +KD    +     K GF N+FG+QRFGS    +H IGK+ 
Sbjct: 127  KLGDLYGNRFLIKVDYPGDLEKDSSETLKEINEKGGFPNFFGVQRFGSMRSNTHYIGKMI 186

Query: 938  IASKWEDMIKLILEPTPQDLPFMRECKMKFKENQNIDEFLKASCNGI--ERSLVSGISKH 1111
            I  ++E      L     D     E ++ + +N +    LK     +  ERS++  I+  
Sbjct: 187  IKGEYEKAADKYLYDDNFD---TEEYRINYGKNMDAKNSLKEYPGNLTFERSILGAIAS- 242

Query: 1112 GYILNAIDTLPRNLKQLYVHSYQSYVWNKIASMRIRECGN-SAVMAGDLIEIGDQQVIVV 1288
            G   +A + LP+NL  ++VH++QSY++NK+ S R++   +   V+ GDL+   D      
Sbjct: 243  GNKSSAFNALPKNLSIMFVHAFQSYLFNKMLSERMKHVKDLKTVIEGDLLYNIDDYFNPD 302

Query: 1289 DE--ADVNKYTIGDV-----------VLPLPGYDVKLPE 1366
             +   + N+Y +  +           V+PLPG+D ++P+
Sbjct: 303  KKRLIEANRYNLEMLNNLSSMDKIRPVIPLPGFDTRMPD 341

>sp|O28596|TRUD_ARCFU Probable tRNA pseudouridine synthase D (tRNA-uridine isomerase D)
            (tRNA pseudouridylate synthase D)
          Length = 411

 Score =  117 bits (293), Expect = 8e-26
 Identities = 84/304 (27%), Positives = 152/304 (50%), Gaps = 21/304 (6%)
 Frame = +2

Query: 512  SGDDDYCQFVLYKEGKDTISAISLIAKYLKMKPGSFTYAGTKDRRGITSQLVRIRSCAAN 691
            S + D+    + K+  DT++   +++  L +     ++AGTKD+R +T Q   I      
Sbjct: 39   SDEGDFLIIRVEKKNWDTLNFARVLSNALGISQKRISFAGTKDKRALTVQYFSIYGVKKE 98

Query: 692  RLKGLNKCLNGIVLGNFSYHHSPLKLGDLYGNRFRLVIRDVHGSDKDIEAAIDRFKKGFI 871
             ++ +N  L    +    Y    ++LGDL GN FR+ +      +   E   +  +KG  
Sbjct: 99   EIERVN--LKDAKIEVIGYARRAIQLGDLLGNFFRIRVYGCRDGEIFQETRNELMEKGTP 156

Query: 872  NYFGMQRFGSTEIRSHEIGKLAIASKWEDMIKLIL----EPTPQDLPFMRECKMKFKEN- 1036
            N+FG+QRFGS    +HE+GKL + + +E+   + +    E   +++  +RE   + ++  
Sbjct: 157  NFFGLQRFGSIRFITHEVGKLILQNNYEEAFWVYVAKPFEGENEEVRKIREILWETRDAK 216

Query: 1037 ---QNIDEFLKASCNGIERSLVSGISKHGYILNAIDTLPRNLKQLYVHSYQSYVWNKIAS 1207
               + + ++L+      ER+L+  + +      A+ +LP+NLK ++VH+YQSY++N++ S
Sbjct: 217  LGLRELPKYLR-----YERNLLQKLREGKSEEEALLSLPKNLKMMFVHAYQSYIFNRLLS 271

Query: 1208 MRIRECGN-SAVMAGDLI---------EIGDQQVIVVDEADVN---KYTIGDVVLPLPGY 1348
             RIR+ G+   +  GD              D   + V+EA V    K  +  + LPL GY
Sbjct: 272  ERIRQFGSLKTLEEGDFACYLTFKTRPTFSDCSEVEVNEARVRFLVKERVASLALPLVGY 331

Query: 1349 DVKL 1360
            D KL
Sbjct: 332  DTKL 335

>sp|Q9HLL3|TRUD_THEAC Probable tRNA pseudouridine synthase D (tRNA-uridine isomerase D)
            (tRNA pseudouridylate synthase D)
          Length = 411

 Score =  115 bits (289), Expect = 2e-25
 Identities = 78/237 (32%), Positives = 123/237 (51%), Gaps = 6/237 (2%)
 Frame = +2

Query: 560  DTISAISLIAKYLKMKPGSFTYAGTKDRRGITSQLVRIRS---CAANRLKGLNKCLNGIV 730
            DT   +  IA  L++     +YAGTKD+R    Q   I +    +    KG        +
Sbjct: 53   DTNRIVEEIASALRISRKRISYAGTKDKRARKIQYFCINAPVDVSVLAFKGFR------I 106

Query: 731  LGNFSYHHSPLKLGDLYGNRFRLVIRDVHGSDKDIEAAIDRFKK--GFINYFGMQRFGST 904
            +  F   H  L+LGDL  N FR  IR    SD  IE   ++  +  GF NYFG QRFGS 
Sbjct: 107  IDRFRSDHY-LRLGDLTANHFR--IRFQGASDDYIEQRYEKMMECGGFPNYFGQQRFGSR 163

Query: 905  EIRSHEIGKLAIASKWEDMIKLILEPTPQDLP-FMRECKMKFKENQNIDEFLKASCNGIE 1081
               +H++G+L +  ++ED ++L L     D+  + RE       N+ +++F +      E
Sbjct: 164  RRNTHDVGRLIVTGRYEDAVRLYLYDERYDIEDYRREFIETLDYNRALEKFPRTL--RFE 221

Query: 1082 RSLVSGISKHGYILNAIDTLPRNLKQLYVHSYQSYVWNKIASMRIRECGNSAVMAGD 1252
            RS++   ++H     A D LP+NL  ++VH+YQSY++N++ S+RI + G +  + GD
Sbjct: 222  RSIIGYYAQHHTFKGAFDALPKNLSIMFVHAYQSYLFNRMLSLRIEKYGLNRAIPGD 278

>sp|Q978K9|TRUD_THEVO Probable tRNA pseudouridine synthase D (tRNA-uridine isomerase D)
            (tRNA pseudouridylate synthase D)
          Length = 409

 Score =  111 bits (277), Expect = 6e-24
 Identities = 79/237 (33%), Positives = 124/237 (52%), Gaps = 5/237 (2%)
 Frame = +2

Query: 560  DTISAISLIAKYLKMKPGSFTYAGTKDRRGITSQLVRIRSCAANRLKGLNKCLNGIVLGN 739
            DT    + IA+ L M     T+AGTKD+R +  Q   I S   + +  L+   +  V+ +
Sbjct: 47   DTNRIAAEIARRLHMSRKRVTFAGTKDKRAVKLQYFCINSADVD-VASLSGIKDFEVIES 105

Query: 740  FSYHHSPLKLGDLYGNRFRLVIRDVHGSDKDIEAAIDRF-----KKGFINYFGMQRFGST 904
            F   H  L LGDL  N F++    +     D E   +R+     K GF N+FG QRFGS 
Sbjct: 106  FKSSHY-LTLGDLIANHFKIRFYGI-----DPEMFRERYVHIISKGGFPNFFGDQRFGSR 159

Query: 905  EIRSHEIGKLAIASKWEDMIKLILEPTPQDLPFMRECKMKFKENQNIDEFLKASCNGIER 1084
               +HEIGKL I  ++E+ +K  +     D    R+  +   + +   E    S +  ER
Sbjct: 160  RRNTHEIGKLIIKGEYEEAVKKYIYDEKYDKESYRKHFIDTLDYKTALERFPHSLS-FER 218

Query: 1085 SLVSGISKHGYILNAIDTLPRNLKQLYVHSYQSYVWNKIASMRIRECGNSAVMAGDL 1255
            SL+   +++G    A D+LP+NL  ++VH+YQSY++N+I   R++  G +AV+ GD+
Sbjct: 219  SLIGYYARNGTFKGAFDSLPKNLTIMFVHAYQSYLFNRILDERLKIYGLNAVLPGDI 275

>sp|Q8TKX2|TRUD_METAC Probable tRNA pseudouridine synthase D (tRNA-uridine isomerase D)
            (tRNA pseudouridylate synthase D)
          Length = 441

 Score =  110 bits (274), Expect = 1e-23
 Identities = 101/344 (29%), Positives = 161/344 (46%), Gaps = 28/344 (8%)
 Frame = +2

Query: 410  NLYG-NTELKDGKRVFIVTNYEDERSQIAKKISKTSGDDD--YCQFVLYKEGKDTISAIS 580
            NLY  NTE   G+    V ++      I K+I+      D  Y    L K   DT     
Sbjct: 16   NLYSTNTEGLGGRLRQEVEDF------IVKEITNREEGKDGRYLVLELTKRDWDTHHFTR 69

Query: 581  LIAKYLKMKPGSFTYAGTKDRRGITSQLVRIRSCAANRLKGLNKCLNGIVLGNFSYHHSP 760
             +AK L++     + AGTKD+R +T+Q + I    A  ++ ++  L  + L         
Sbjct: 70   TLAKILQISQKRISVAGTKDKRALTTQKISIFDIDALEIEKIH--LKDVELKVLGRSRKS 127

Query: 761  LKLGDLYGNRFRLVIRDVHGSDKDIEAAIDRFKK------GFINYFGMQRFGSTEIRSHE 922
            ++LGDL+GN F + IRD+  S ++    +++         G  N+FG+QRFGS    +H 
Sbjct: 128  VELGDLWGNEFIITIRDISSSPEETRTILEKTNSKVLTQGGVPNFFGVQRFGSVRSVTHL 187

Query: 923  IGKLAIASKWEDMIKL-ILEPTPQDLPFMRECKMKFKENQNIDEFLKASCN--GIERSLV 1093
            +GK  +   +E    L I EP P++    +  +   KE ++  E LK      G ER+++
Sbjct: 188  VGKAIVEGNFEKAAMLYIAEPFPEEPEETKAARQFVKETRDFKEGLKTYPLRLGHERAMM 247

Query: 1094 SG-ISKHGYILNAIDTLPRNLKQLYVHSYQSYVWNKIASMRIRECGNS--AVMAGDLI-- 1258
            +  IS       A   LP+NL +++VH+YQSY++N I   RI E G S    + GD++  
Sbjct: 248  NHLISNPEDYSGAFSVLPKNLYRMFVHAYQSYIYNMILCRRI-ESGISLNRAVEGDIVCF 306

Query: 1259 --EIG---DQQVIVVDEADVN------KYTIGDVVLPLPGYDVK 1357
              E G     +   V    VN      K+    +  PLPG++ +
Sbjct: 307  RNEAGLPDSSKTEKVTSETVNAMNRLIKHGRAFITAPLPGFNTE 350

>sp|Q58008|TRUD1_METJA Probable tRNA pseudouridine synthase D 1 (tRNA-uridine isomerase D 1)
            (tRNA pseudouridylate synthase D 1)
          Length = 392

 Score =  108 bits (270), Expect = 4e-23
 Identities = 77/251 (30%), Positives = 128/251 (50%), Gaps = 6/251 (2%)
 Frame = +2

Query: 524  DYCQFVLYKEGKDTISAISLIAKYLKMKPGSFTYAGTKDRRGITSQLVRIRSCAANRLKG 703
            +Y  F L K    T+ AI  IA  +  +   F +AG KD+  +T+Q V    C   +L+ 
Sbjct: 54   NYIHFTLEKRNWTTLDAIREIANRVGKQRKHFGFAGNKDKYAVTTQRV---GCFNVKLED 110

Query: 704  LNKC-LNGIVLGNFSYHHSPLKLGDLYGNRFRLVIRDVHGSDKDIEAAIDRF--KKGFIN 874
            L K  + GI+L +F   +  ++LGDL+GNRF + +R+     K++E A+++    K F+N
Sbjct: 111  LMKVKIKGIILRDFQKTNRKIRLGDLWGNRFTIRVREPELKGKELEEALNKLCKLKYFLN 170

Query: 875  YFGMQRFGSTEIRSHEIGKLAIASKWEDMIKLIL-EPTPQDLPFMRECKMKFKENQNIDE 1051
            Y+G+QRFG+T   +H +G+  I   WE         P P D     +   +  + +N  E
Sbjct: 171  YYGVQRFGTTRPITHIVGRFIIERDWEGAFHAYCGTPLPYD-DKKSKLARELVDEENFKE 229

Query: 1052 FLKASCNGI--ERSLVSGISKHGYILNAIDTLPRNLKQLYVHSYQSYVWNKIASMRIREC 1225
              K        ER ++    + G    A   LP  L+ +++++YQSY++N+I + R  E 
Sbjct: 230  AYKKFPKAFFYERRMIKAYIETGSYQKAFMILPPYLRCMFINAYQSYLFNEIINRRF-EY 288

Query: 1226 GNSAVMAGDLI 1258
            G    M GD++
Sbjct: 289  GFEP-MEGDIL 298

  Database: Non-redundant SwissProt sequences
    Posted date:  Dec 6, 2005  7:40 AM
  Number of letters in database: 68,354,980
  Number of sequences in database:  184,735
  
  Database: swissprot.01
    Posted date:  Dec 6, 2005  8:18 AM
  Number of letters in database: 66,202,850
  Number of sequences in database:  184,431
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 153,017,840
Number of Sequences: 369166
Number of extensions: 3151773
Number of successful extensions: 8176
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 7609
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 8043
length of database: 68,354,980
effective HSP length: 114
effective length of database: 47,295,190
effective search space used: 16174954980
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)

Cluster detail

DrC_00074

  1. Dr_sW_002_O02
  2. Dr_sW_026_C15