Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= DrC_03075
(554 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P35208|SPT10_YEAST SPT10 protein 35 0.095
sp|P59047|NALP5_HUMAN NACHT-, LRR- and PYD-containing prote... 34 0.21
sp|P10775|RINI_PIG Ribonuclease inhibitor (Ribonuclease/ang... 33 0.36
sp|Q9C000|NALP1_HUMAN NACHT-, LRR- and PYD-containing prote... 33 0.47
sp|Q96P20|CIAS1_HUMAN Cold autoinflammatory syndrome 1 prot... 33 0.47
sp|Q9Y239|CARD4_HUMAN Caspase recruitment domain protein 4 ... 32 1.4
sp|Q8HZP9|RINI_PANTR Ribonuclease inhibitor (Ribonuclease/a... 32 1.4
sp|Q86W24|NAL14_HUMAN NACHT-, LRR- and PYD-containing prote... 31 1.8
sp|P13489|RINI_HUMAN Ribonuclease inhibitor (Ribonuclease/a... 31 2.3
sp|Q59801|HYSA_STAAU Hyaluronate lyase precursor (Hyaluroni... 30 3.0
>sp|P35208|SPT10_YEAST SPT10 protein
Length = 640
Score = 35.4 bits (80), Expect = 0.095
Identities = 23/60 (38%), Positives = 34/60 (56%), Gaps = 2/60 (3%)
Frame = +2
Query: 377 LLKTIIANSKDLEDIDLFGNDI--GDLGSRQLLEGLMMRKVNKLPQIGIRVGHRINQDTF 550
L++T I SK L F I ++G R++LEGL R++ KLP+ GI G + D+F
Sbjct: 204 LMETFIEWSKKLGFTSSFFPLIYGTNVGIRRILEGLNFRRIGKLPEAGILKGFDVPVDSF 263
>sp|P59047|NALP5_HUMAN NACHT-, LRR- and PYD-containing protein 5 (Mater protein homolog)
Length = 1200
Score = 34.3 bits (77), Expect = 0.21
Identities = 18/51 (35%), Positives = 31/51 (60%)
Frame = +2
Query: 368 CMQLLKTIIANSKDLEDIDLFGNDIGDLGSRQLLEGLMMRKVNKLPQIGIR 520
C + L +I+ S+ L+ +DL N +GD G L EGL +K + L ++G++
Sbjct: 1053 CCESLSCVISRSRHLKSLDLTDNALGDGGVAALCEGL-KQKNSVLTRLGLK 1102
>sp|P10775|RINI_PIG Ribonuclease inhibitor (Ribonuclease/angiogenin inhibitor 1)
Length = 456
Score = 33.5 bits (75), Expect = 0.36
Identities = 21/63 (33%), Positives = 31/63 (49%)
Frame = +2
Query: 293 QIEKLRLADNGIDQMGRGGNFAPMRCMQLLKTIIANSKDLEDIDLFGNDIGDLGSRQLLE 472
Q+E LRL + G+ P C L I+A+ L ++DL N +GD G +L
Sbjct: 195 QLETLRLENCGL---------TPANCKDLCG-IVASQASLRELDLGSNGLGDAGIAELCP 244
Query: 473 GLM 481
GL+
Sbjct: 245 GLL 247
>sp|Q9C000|NALP1_HUMAN NACHT-, LRR- and PYD-containing protein 2 (Death effector
filament-forming ced-4-like apoptosis protein)
(Nucleotide-binding domain and caspase recruitment
domain) (Caspase recruitment domain protein 7)
Length = 1473
Score = 33.1 bits (74), Expect = 0.47
Identities = 15/37 (40%), Positives = 25/37 (67%)
Frame = +2
Query: 368 CMQLLKTIIANSKDLEDIDLFGNDIGDLGSRQLLEGL 478
C Q L ++++ S L+++DL N++ D+G R L EGL
Sbjct: 910 CCQDLASVLSASPSLKELDLQQNNLDDVGVRLLCEGL 946
>sp|Q96P20|CIAS1_HUMAN Cold autoinflammatory syndrome 1 protein (Cryopyrin) (NACHT-, LRR-
and PYD-containing protein 3) (PYRIN-containing
APAF1-like protein 1) (Angiotensin/vasopressin receptor
AII/AVP-like)
Length = 1034
Score = 33.1 bits (74), Expect = 0.47
Identities = 17/62 (27%), Positives = 34/62 (54%)
Frame = +2
Query: 296 IEKLRLADNGIDQMGRGGNFAPMRCMQLLKTIIANSKDLEDIDLFGNDIGDLGSRQLLEG 475
++KL L ++G+ + C L ++++ +++L + L GN +GD G + L EG
Sbjct: 884 LQKLGLVNSGLTSV----------CCSALSSVLSTNQNLTHLYLRGNTLGDKGIKLLCEG 933
Query: 476 LM 481
L+
Sbjct: 934 LL 935
Score = 29.6 bits (65), Expect = 5.2
Identities = 14/37 (37%), Positives = 20/37 (54%)
Frame = +2
Query: 368 CMQLLKTIIANSKDLEDIDLFGNDIGDLGSRQLLEGL 478
C L T++ +S+ L + L ND+GDLG E L
Sbjct: 955 CCWDLSTLLTSSQSLRKLSLGNNDLGDLGVMMFCEVL 991
>sp|Q9Y239|CARD4_HUMAN Caspase recruitment domain protein 4 (Nod1 protein)
Length = 953
Score = 31.6 bits (70), Expect = 1.4
Identities = 14/52 (26%), Positives = 26/52 (50%)
Frame = +2
Query: 323 GIDQMGRGGNFAPMRCMQLLKTIIANSKDLEDIDLFGNDIGDLGSRQLLEGL 478
G+ + G N + L + NSK + ++ ++GN +GD G++ E L
Sbjct: 785 GLTHLKLGKNKITSEGGKYLALAVKNSKSISEVGMWGNQVGDEGAKAFAEAL 836
>sp|Q8HZP9|RINI_PANTR Ribonuclease inhibitor (Ribonuclease/angiogenin inhibitor 1)
Length = 461
Score = 31.6 bits (70), Expect = 1.4
Identities = 22/77 (28%), Positives = 35/77 (45%), Gaps = 15/77 (19%)
Frame = +2
Query: 293 QIEKLRLADNGIDQMGRG---------------GNFAPMRCMQLLKTIIANSKDLEDIDL 427
QI RL D G+ ++ +G + + C L T++AN L ++DL
Sbjct: 347 QISNNRLEDAGVQELCQGLGQPGSVLRVLWLADCDVSDSSCSSLAATLLANHS-LRELDL 405
Query: 428 FGNDIGDLGSRQLLEGL 478
N +GD G QL+E +
Sbjct: 406 SNNCLGDAGILQLVESV 422
>sp|Q86W24|NAL14_HUMAN NACHT-, LRR- and PYD-containing protein 14 (Nucleotide-binding
oligomerization domain protein 5)
Length = 1093
Score = 31.2 bits (69), Expect = 1.8
Identities = 15/35 (42%), Positives = 23/35 (65%)
Frame = +2
Query: 374 QLLKTIIANSKDLEDIDLFGNDIGDLGSRQLLEGL 478
Q + T + ++K+L +DL G+DIGD G + L E L
Sbjct: 719 QDISTSLIHNKNLMHLDLKGSDIGDNGVKSLCEAL 753
>sp|P13489|RINI_HUMAN Ribonuclease inhibitor (Ribonuclease/angiogenin inhibitor 1) (RAI)
(Placental ribonuclease inhibitor) (RNase inhibitor)
(RI)
Length = 461
Score = 30.8 bits (68), Expect = 2.3
Identities = 22/77 (28%), Positives = 35/77 (45%), Gaps = 15/77 (19%)
Frame = +2
Query: 293 QIEKLRLADNGIDQMGRG---------------GNFAPMRCMQLLKTIIANSKDLEDIDL 427
QI RL D G+ ++ +G + + C L T++AN L ++DL
Sbjct: 347 QISNNRLEDAGVRELCQGLGQPGSVLRVLWLADCDVSDSSCSSLAATLLANHS-LRELDL 405
Query: 428 FGNDIGDLGSRQLLEGL 478
N +GD G QL+E +
Sbjct: 406 SNNCLGDAGILQLVESV 422
>sp|Q59801|HYSA_STAAU Hyaluronate lyase precursor (Hyaluronidase) (HYase)
Length = 807
Score = 30.4 bits (67), Expect = 3.0
Identities = 19/58 (32%), Positives = 31/58 (53%), Gaps = 2/58 (3%)
Frame = +2
Query: 263 FMAPPPPVGPQIEKLRLADNGIDQMGRGGNFAPMRCMQLLKTIIANSKDL--EDIDLF 430
F AP P +K+ L+ G ++ +GGN + ++LL+ II KD+ + ID F
Sbjct: 213 FTAPIKTFAPDSDKI-LSSVGKAELAKGGNLVDISKVKLLECIIEEDKDMMKKSIDSF 269
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 48,800,468
Number of Sequences: 369166
Number of extensions: 742132
Number of successful extensions: 1960
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 1867
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 1959
length of database: 68,354,980
effective HSP length: 104
effective length of database: 49,142,540
effective search space used: 3931403200
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)