Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= DrC_03067
(921 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q8HYN7|KCIP4_MACFA Kv channel-interacting protein 4 (KCh... 75 3e-13
sp|Q6PHZ8|KCIP4_MOUSE Kv channel-interacting protein 4 (KCh... 75 3e-13
sp|Q9JJ57|KCIP1_MOUSE Kv channel-interacting protein 1 (KCh... 70 6e-12
sp|Q9NZI2|KCIP1_HUMAN Kv channel-interacting protein 1 (KCh... 70 6e-12
sp|Q8R426|KCIP1_RAT Kv channel-interacting protein 1 (KChIP... 70 6e-12
sp|Q9NS61|KCIP2_HUMAN Kv channel-interacting protein 2 (KCh... 68 4e-11
sp|Q9JJ69|KCIP2_MOUSE Kv channel-interacting protein 2 (KCh... 68 4e-11
sp|Q8WN03|KCIP2_MUSPF Kv channel-interacting protein 2 (KCh... 67 5e-11
sp|P37236|FREQ_DROME Frequenin-1 (d-FRQ) 67 7e-11
sp|Q9Y2W7|CSEN_HUMAN Calsenilin (DRE-antagonist modulator) ... 67 9e-11
>sp|Q8HYN7|KCIP4_MACFA Kv channel-interacting protein 4 (KChIP4) (A-type potassium channel
modulatory protein 4) (Potassium channel-interacting
protein 4)
sp|Q6PIL6|KCIP4_HUMAN Kv channel-interacting protein 4 (KChIP4) (A-type potassium channel
modulatory protein 4) (Potassium channel-interacting
protein 4) (Calsenilin-like protein)
Length = 250
Score = 74.7 bits (182), Expect = 3e-13
Identities = 34/87 (39%), Positives = 55/87 (63%)
Frame = +1
Query: 286 FKVFVYQFNLLLGKGSTARFARLLYGSIKNKNETVMKFEDFLRTIDILANGDVLEKLNWT 465
FK QF +G + +A L+ + + + FEDF++ + IL G V EKLNW
Sbjct: 108 FKEIYSQF---FPQGDSTTYAHFLFNAFDTDHNGAVSFEDFIKGLSILLRGTVQEKLNWA 164
Query: 466 FDLYDIDKDGIISKEDLIEVMSAIFNI 546
F+LYDI+KDG I+KE+++++M AI+++
Sbjct: 165 FNLYDINKDGYITKEEMLDIMKAIYDM 191
>sp|Q6PHZ8|KCIP4_MOUSE Kv channel-interacting protein 4 (KChIP4) (A-type potassium channel
modulatory protein 4) (Potassium channel-interacting
protein 4) (Calsenilin-like protein)
sp|Q99MG9|KCIP4_RAT Kv channel-interacting protein 4 (KChIP4) (A-type potassium channel
modulatory protein 4) (Potassium channel-interacting
protein 4)
Length = 250
Score = 74.7 bits (182), Expect = 3e-13
Identities = 34/87 (39%), Positives = 55/87 (63%)
Frame = +1
Query: 286 FKVFVYQFNLLLGKGSTARFARLLYGSIKNKNETVMKFEDFLRTIDILANGDVLEKLNWT 465
FK QF +G + +A L+ + + + FEDF++ + IL G V EKLNW
Sbjct: 108 FKEIYSQF---FPQGDSTTYAHFLFNAFDTDHNGAVSFEDFIKGLSILLRGTVQEKLNWA 164
Query: 466 FDLYDIDKDGIISKEDLIEVMSAIFNI 546
F+LYDI+KDG I+KE+++++M AI+++
Sbjct: 165 FNLYDINKDGYITKEEMLDIMKAIYDM 191
>sp|Q9JJ57|KCIP1_MOUSE Kv channel-interacting protein 1 (KChIP1) (A-type potassium channel
modulatory protein 1) (Potassium channel-interacting
protein 1)
Length = 227
Score = 70.5 bits (171), Expect = 6e-12
Identities = 30/73 (41%), Positives = 49/73 (67%)
Frame = +1
Query: 328 GSTARFARLLYGSIKNKNETVMKFEDFLRTIDILANGDVLEKLNWTFDLYDIDKDGIISK 507
G + +A L+ + +KFEDF+ + IL G V EKL WTF+LYDI+KDG I+K
Sbjct: 96 GDASTYAHYLFNAFDTTQTGSVKFEDFVTALSILLRGTVHEKLRWTFNLYDINKDGYINK 155
Query: 508 EDLIEVMSAIFNI 546
E++++++ AI+++
Sbjct: 156 EEMMDIVKAIYDM 168
>sp|Q9NZI2|KCIP1_HUMAN Kv channel-interacting protein 1 (KChIP1) (A-type potassium channel
modulatory protein 1) (Potassium channel-interacting
protein 1) (Vesicle APC-binding protein)
Length = 227
Score = 70.5 bits (171), Expect = 6e-12
Identities = 30/73 (41%), Positives = 49/73 (67%)
Frame = +1
Query: 328 GSTARFARLLYGSIKNKNETVMKFEDFLRTIDILANGDVLEKLNWTFDLYDIDKDGIISK 507
G + +A L+ + +KFEDF+ + IL G V EKL WTF+LYDI+KDG I+K
Sbjct: 96 GDASTYAHYLFNAFDTTQTGSVKFEDFVTALSILLRGTVHEKLRWTFNLYDINKDGYINK 155
Query: 508 EDLIEVMSAIFNI 546
E++++++ AI+++
Sbjct: 156 EEMMDIVKAIYDM 168
>sp|Q8R426|KCIP1_RAT Kv channel-interacting protein 1 (KChIP1) (A-type potassium channel
modulatory protein 1) (Potassium channel-interacting
protein 1)
Length = 227
Score = 70.5 bits (171), Expect = 6e-12
Identities = 30/73 (41%), Positives = 49/73 (67%)
Frame = +1
Query: 328 GSTARFARLLYGSIKNKNETVMKFEDFLRTIDILANGDVLEKLNWTFDLYDIDKDGIISK 507
G + +A L+ + +KFEDF+ + IL G V EKL WTF+LYDI+KDG I+K
Sbjct: 96 GDASTYAHYLFNAFDTTQTGSVKFEDFVTALSILLRGTVHEKLRWTFNLYDINKDGYINK 155
Query: 508 EDLIEVMSAIFNI 546
E++++++ AI+++
Sbjct: 156 EEMMDIVKAIYDM 168
>sp|Q9NS61|KCIP2_HUMAN Kv channel-interacting protein 2 (KChIP2) (A-type potassium channel
modulatory protein 2) (Potassium channel-interacting
protein 2) (Cardiac voltage gated potassium channel
modulatory subunit)
Length = 270
Score = 67.8 bits (164), Expect = 4e-11
Identities = 32/121 (26%), Positives = 67/121 (55%)
Frame = +1
Query: 286 FKVFVYQFNLLLGKGSTARFARLLYGSIKNKNETVMKFEDFLRTIDILANGDVLEKLNWT 465
FK QF +G ++ +A L+ + ++ + FEDF+ + ++ G V ++LNW
Sbjct: 128 FKQIYSQF---FPQGDSSTYATFLFNAFDTNHDGSVSFEDFVAGLSVILRGTVDDRLNWA 184
Query: 466 FDLYDIDKDGIISKEDLIEVMSAIFNISNDIFCVDTSKNVWVDYSISLMSKIDKLPSALM 645
F+LYD++KDG I+KE+++++M +I+++ + ++ S K+D+ ++
Sbjct: 185 FNLYDLNKDGCITKEEMLDIMKSIYDMMGKYTYPALREEApreHVESFFQKMDRNKDGVV 244
Query: 646 T 648
T
Sbjct: 245 T 245
>sp|Q9JJ69|KCIP2_MOUSE Kv channel-interacting protein 2 (KChIP2) (A-type potassium channel
modulatory protein 2) (Potassium channel-interacting
protein 2)
Length = 270
Score = 67.8 bits (164), Expect = 4e-11
Identities = 31/121 (25%), Positives = 67/121 (55%)
Frame = +1
Query: 286 FKVFVYQFNLLLGKGSTARFARLLYGSIKNKNETVMKFEDFLRTIDILANGDVLEKLNWT 465
FK QF +G ++ +A L+ + ++ + FEDF+ + ++ G + ++LNW
Sbjct: 128 FKQIYSQF---FPQGDSSNYATFLFNAFDTNHDGSVSFEDFVAGLSVILRGTIDDRLNWA 184
Query: 466 FDLYDIDKDGIISKEDLIEVMSAIFNISNDIFCVDTSKNVWVDYSISLMSKIDKLPSALM 645
F+LYD++KDG I+KE+++++M +I+++ + ++ S K+D+ ++
Sbjct: 185 FNLYDLNKDGCITKEEMLDIMKSIYDMMGKYTYPALREEApreHVESFFQKMDRNKDGVV 244
Query: 646 T 648
T
Sbjct: 245 T 245
>sp|Q8WN03|KCIP2_MUSPF Kv channel-interacting protein 2 (KChIP2) (A-type potassium channel
modulatory protein 2) (Potassium channel-interacting
protein 2)
Length = 270
Score = 67.4 bits (163), Expect = 5e-11
Identities = 31/121 (25%), Positives = 67/121 (55%)
Frame = +1
Query: 286 FKVFVYQFNLLLGKGSTARFARLLYGSIKNKNETVMKFEDFLRTIDILANGDVLEKLNWT 465
FK QF +G ++ +A L+ + ++ + FEDF+ + ++ G + ++LNW
Sbjct: 128 FKQIYSQF---FPQGDSSTYATFLFNAFDTNHDGSVSFEDFVAGLSVILRGTIDDRLNWA 184
Query: 466 FDLYDIDKDGIISKEDLIEVMSAIFNISNDIFCVDTSKNVWVDYSISLMSKIDKLPSALM 645
F+LYD++KDG I+KE+++++M +I+++ + ++ S K+D+ ++
Sbjct: 185 FNLYDLNKDGCITKEEMLDIMKSIYDMMGKYTYPALREEApreHVESFFQKMDRNKDGVV 244
Query: 646 T 648
T
Sbjct: 245 T 245
>sp|P37236|FREQ_DROME Frequenin-1 (d-FRQ)
Length = 187
Score = 67.0 bits (162), Expect = 7e-11
Identities = 26/84 (30%), Positives = 52/84 (61%)
Frame = +1
Query: 295 FVYQFNLLLGKGSTARFARLLYGSIKNKNETVMKFEDFLRTIDILANGDVLEKLNWTFDL 474
F+ + +G ++FA L++ N+ ++FE+F+R + + + G++ EKL W F L
Sbjct: 48 FIKIYKQFFPQGDPSKFASLVFRVFDENNDGSIEFEEFIRALSVTSKGNLDEKLQWAFRL 107
Query: 475 YDIDKDGIISKEDLIEVMSAIFNI 546
YD+D DG I++E++ ++ AI+ +
Sbjct: 108 YDVDNDGYITREEMYNIVDAIYQM 131
>sp|Q9Y2W7|CSEN_HUMAN Calsenilin (DRE-antagonist modulator) (DREAM) (Kv
channel-interacting protein 3) (KChIP3) (A-type
potassium channel modulatory protein 3)
Length = 256
Score = 66.6 bits (161), Expect = 9e-11
Identities = 32/87 (36%), Positives = 51/87 (58%)
Frame = +1
Query: 286 FKVFVYQFNLLLGKGSTARFARLLYGSIKNKNETVMKFEDFLRTIDILANGDVLEKLNWT 465
FK+ QF +G +A L+ + + FEDF+ + IL G V EKL W
Sbjct: 114 FKLIYAQF---FPQGDATTYAHFLFNAFDADGNGAIHFEDFVVGLSILLRGTVHEKLKWA 170
Query: 466 FDLYDIDKDGIISKEDLIEVMSAIFNI 546
F+LYDI+KDG I+KE+++ +M +I+++
Sbjct: 171 FNLYDINKDGYITKEEMLAIMKSIYDM 197
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 95,040,870
Number of Sequences: 369166
Number of extensions: 1804890
Number of successful extensions: 4804
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 4577
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4795
length of database: 68,354,980
effective HSP length: 110
effective length of database: 48,034,130
effective search space used: 9414689480
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)