Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= DrC_03035
(681 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q5BKM3|CHMP3_XENTR Charged multivesicular body protein 3... 176 4e-44
sp|Q6NRM7|CHMP3_XENLA Charged multivesicular body protein 3... 175 9e-44
sp|Q6NY88|CHMP3_BRARE Charged multivesicular body protein 3... 175 9e-44
sp|Q8CGS4|CHMP3_RAT Charged multivesicular body protein 3 (... 173 3e-43
sp|Q5RAU5|CHMP3_PONPY Charged multivesicular body protein 3... 172 6e-43
sp|Q9Y3E7|CHMP3_HUMAN Charged multivesicular body protein 3... 172 7e-43
sp|Q9CQ10|CHMP3_MOUSE Charged multivesicular body protein 3... 172 1e-42
sp|Q4R574|CHMP3_MACFA Charged multivesicular body protein 3... 171 1e-42
sp|Q58CS7|CHMP3_BOVIN Charged multivesicular body protein 3... 171 2e-42
sp|Q6NXD2|CHM2B_BRARE Charged multivesicular body protein 2... 95 2e-19
>sp|Q5BKM3|CHMP3_XENTR Charged multivesicular body protein 3 (Chromatin modifying protein
3) (Vacuolar protein sorting 24)
Length = 220
Score = 176 bits (447), Expect = 4e-44
Identities = 92/198 (46%), Positives = 140/198 (70%)
Frame = +2
Query: 2 EERKLDRDINSIDRSLKQQELEIKKYAKQGNLDAAKILAKELINAKKSISRLYSAKAQMN 181
E R +DR I I R ++ + IK+ AK+GN +A ILAKE++++KK++++LY++KA MN
Sbjct: 26 EMRLIDRQIRDIQREQEKVKRSIKESAKKGNREACVILAKEVVHSKKAVNKLYASKAHMN 85
Query: 182 SVVMNLNHQASLVRMAGTLQKSTEVMKSMSSLIKVPEIQKTMQELSKEMTKAGIMEELVN 361
SV+M++ +Q +++R++G+LQKSTEVMK+M +L+K+PEIQ TM++LSKEM KAGI+EE++
Sbjct: 86 SVLMSMKNQLAVLRVSGSLQKSTEVMKAMQNLVKIPEIQATMRDLSKEMMKAGIIEEMLE 145
Query: 362 DTLXXXXXXXXXXXXXXXXXVDKILFDLTAGAMGAAPDAVRDTLPSGTPVAKGASSSVPV 541
DT +D+ILF++TAGA+G AP V D LP P GA ++
Sbjct: 146 DTF-EGMEDQDEMEEQAEMEIDRILFEITAGALGKAPSKVTDALPE--PEITGAMAASDE 202
Query: 542 EDDEDFDEMKARLEALRS 595
E++ED + M++RL ALRS
Sbjct: 203 EEEEDLEAMQSRLAALRS 220
>sp|Q6NRM7|CHMP3_XENLA Charged multivesicular body protein 3 (Chromatin modifying protein
3) (Vacuolar protein sorting 24)
Length = 220
Score = 175 bits (444), Expect = 9e-44
Identities = 93/198 (46%), Positives = 138/198 (69%)
Frame = +2
Query: 2 EERKLDRDINSIDRSLKQQELEIKKYAKQGNLDAAKILAKELINAKKSISRLYSAKAQMN 181
E R +DR I I R ++ + IK+ AK+GN +A ILAKE++ +KK++++LY++KA MN
Sbjct: 26 EMRVIDRQIRDIQREQEKVKRSIKESAKKGNREACVILAKEVVQSKKAVNKLYASKAHMN 85
Query: 182 SVVMNLNHQASLVRMAGTLQKSTEVMKSMSSLIKVPEIQKTMQELSKEMTKAGIMEELVN 361
SV+M++ +Q +++R++G+LQKSTEVMK+M +L+K+PEIQ TM+ELSKEM KAGI+EE++
Sbjct: 86 SVLMSMKNQLAVLRVSGSLQKSTEVMKAMQNLVKLPEIQATMRELSKEMMKAGIIEEMLE 145
Query: 362 DTLXXXXXXXXXXXXXXXXXVDKILFDLTAGAMGAAPDAVRDTLPSGTPVAKGASSSVPV 541
DT +D+ILF++TAGA+G AP V D LP P GA ++
Sbjct: 146 DTF-EGMEDQDEMEEQAEMEIDRILFEVTAGALGKAPSKVTDALPE--PEITGAMAASDE 202
Query: 542 EDDEDFDEMKARLEALRS 595
E++ED + M +RL ALRS
Sbjct: 203 EEEEDLEAMHSRLAALRS 220
>sp|Q6NY88|CHMP3_BRARE Charged multivesicular body protein 3 (Chromatin modifying protein
3) (Vacuolar protein sorting 24)
Length = 221
Score = 175 bits (444), Expect = 9e-44
Identities = 96/198 (48%), Positives = 136/198 (68%)
Frame = +2
Query: 2 EERKLDRDINSIDRSLKQQELEIKKYAKQGNLDAAKILAKELINAKKSISRLYSAKAQMN 181
E R +DR I I R ++ + IK AK+G D ILAKE+I +K++I++LY++KAQMN
Sbjct: 26 EMRVIDRQIRDIQREEEKVKRSIKDAAKKGQKDVCIILAKEMIQSKRAINKLYASKAQMN 85
Query: 182 SVVMNLNHQASLVRMAGTLQKSTEVMKSMSSLIKVPEIQKTMQELSKEMTKAGIMEELVN 361
SV++++ +Q S++R+AG LQKSTEVMK+M SL+K+PEIQ TM++LSKEM KAGI+EE++
Sbjct: 86 SVLLSMKNQLSVLRVAGALQKSTEVMKAMQSLVKIPEIQATMRDLSKEMMKAGIIEEMLE 145
Query: 362 DTLXXXXXXXXXXXXXXXXXVDKILFDLTAGAMGAAPDAVRDTLPSGTPVAKGASSSVPV 541
DTL VDKILF++TAGA+G AP V D LP + A+
Sbjct: 146 DTL-EGMDDEEEMEEAAEAEVDKILFEITAGALGKAPSKVTD-LPDPVAIGATAAPEEES 203
Query: 542 EDDEDFDEMKARLEALRS 595
E++E+ +EM++RL ALRS
Sbjct: 204 EEEEEIEEMQSRLAALRS 221
>sp|Q8CGS4|CHMP3_RAT Charged multivesicular body protein 3 (Chromatin modifying protein
3) (Vacuolar protein sorting 24) (mVps24p)
Length = 223
Score = 173 bits (439), Expect = 3e-43
Identities = 93/199 (46%), Positives = 133/199 (66%), Gaps = 1/199 (0%)
Frame = +2
Query: 2 EERKLDRDINSIDRSLKQQELEIKKYAKQGNLDAAKILAKELINAKKSISRLYSAKAQMN 181
E R +DR I I R ++ + +K AK+G + +LAKE+I ++K++S+LY++KA MN
Sbjct: 26 EMRVVDRQIRDIQREEEKVKRSVKDAAKKGQKEVCVVLAKEMIRSRKAVSKLYASKAHMN 85
Query: 182 SVVMNLNHQASLVRMAGTLQKSTEVMKSMSSLIKVPEIQKTMQELSKEMTKAGIMEELVN 361
SV+M + +Q +++R+AG+LQKSTEVMK+M SL+K+PEIQ TM+ELSKEM KAGI+EE++
Sbjct: 86 SVLMGMKNQLAVLRVAGSLQKSTEVMKAMQSLVKIPEIQATMRELSKEMMKAGIIEEMLE 145
Query: 362 DTLXXXXXXXXXXXXXXXXXVDKILFDLTAGAMGAAPDAVRDTLPSGTPVAKGASSSVPV 541
DT +D+ILF++TAGA+G AP V D LP P A+S
Sbjct: 146 DTF-ESMDDQEEMEEAAEMEIDRILFEITAGALGKAPSKVTDALPEPEPAGAMAASEGDE 204
Query: 542 EDD-EDFDEMKARLEALRS 595
EDD ED + M++RL LRS
Sbjct: 205 EDDEEDLEAMQSRLATLRS 223
>sp|Q5RAU5|CHMP3_PONPY Charged multivesicular body protein 3 (Chromatin modifying protein
3) (Vacuolar protein sorting 24)
Length = 222
Score = 172 bits (437), Expect = 6e-43
Identities = 91/198 (45%), Positives = 132/198 (66%)
Frame = +2
Query: 2 EERKLDRDINSIDRSLKQQELEIKKYAKQGNLDAAKILAKELINAKKSISRLYSAKAQMN 181
E R +DR I I R ++ + +K AK+G D +LAKE+I ++K++S+LY++KA MN
Sbjct: 26 EMRVVDRQIRDIQREEEKVKRSVKDAAKKGQKDVCVVLAKEMIRSRKAVSKLYASKAHMN 85
Query: 182 SVVMNLNHQASLVRMAGTLQKSTEVMKSMSSLIKVPEIQKTMQELSKEMTKAGIMEELVN 361
SV+M + +Q +++R+AG+LQKSTEVMK+M SL+K+PEIQ TM+ELSKEM KAGI+EE++
Sbjct: 86 SVLMGMKNQLAVLRVAGSLQKSTEVMKAMQSLVKIPEIQATMRELSKEMMKAGIIEEMLE 145
Query: 362 DTLXXXXXXXXXXXXXXXXXVDKILFDLTAGAMGAAPDAVRDTLPSGTPVAKGASSSVPV 541
DT +D+ILF++TAGA+G AP V D LP P A+S
Sbjct: 146 DTF-ESMDDQEEMEEEAEMEIDRILFEITAGALGKAPSKVTDALPEPEPSGAMAASEDEE 204
Query: 542 EDDEDFDEMKARLEALRS 595
E++E + M++RL LRS
Sbjct: 205 EEEEALEAMQSRLATLRS 222
>sp|Q9Y3E7|CHMP3_HUMAN Charged multivesicular body protein 3 (Chromatin modifying protein
3) (Vacuolar protein sorting 24) (hVps24)
(Neuroendocrine differentiation factor)
Length = 222
Score = 172 bits (436), Expect = 7e-43
Identities = 91/198 (45%), Positives = 132/198 (66%)
Frame = +2
Query: 2 EERKLDRDINSIDRSLKQQELEIKKYAKQGNLDAAKILAKELINAKKSISRLYSAKAQMN 181
E R +DR I I R ++ + +K AK+G D +LAKE+I ++K++S+LY++KA MN
Sbjct: 26 EMRVVDRQIRDIQREEEKVKRSVKDAAKKGQKDVCIVLAKEMIRSRKAVSKLYASKAHMN 85
Query: 182 SVVMNLNHQASLVRMAGTLQKSTEVMKSMSSLIKVPEIQKTMQELSKEMTKAGIMEELVN 361
SV+M + +Q +++R+AG+LQKSTEVMK+M SL+K+PEIQ TM+ELSKEM KAGI+EE++
Sbjct: 86 SVLMGMKNQLAVLRVAGSLQKSTEVMKAMQSLVKIPEIQATMRELSKEMMKAGIIEEMLE 145
Query: 362 DTLXXXXXXXXXXXXXXXXXVDKILFDLTAGAMGAAPDAVRDTLPSGTPVAKGASSSVPV 541
DT +D+ILF++TAGA+G AP V D LP P A+S
Sbjct: 146 DTF-ESMDDQEEMEEEAEMEIDRILFEITAGALGKAPSKVTDALPEPEPPGAMAASEDEE 204
Query: 542 EDDEDFDEMKARLEALRS 595
E++E + M++RL LRS
Sbjct: 205 EEEEALEAMQSRLATLRS 222
>sp|Q9CQ10|CHMP3_MOUSE Charged multivesicular body protein 3 (Chromatin modifying protein
3) (Vacuolar protein sorting 24)
Length = 224
Score = 172 bits (435), Expect = 1e-42
Identities = 92/200 (46%), Positives = 133/200 (66%), Gaps = 2/200 (1%)
Frame = +2
Query: 2 EERKLDRDINSIDRSLKQQELEIKKYAKQGNLDAAKILAKELINAKKSISRLYSAKAQMN 181
E R +DR I I R ++ + +K AK+G + +LAKE+I ++K++S+LY++KA MN
Sbjct: 26 EMRVVDRQIRDIQREEEKVKRSVKDAAKKGQKEVCVVLAKEMIRSRKAVSKLYASKAHMN 85
Query: 182 SVVMNLNHQASLVRMAGTLQKSTEVMKSMSSLIKVPEIQKTMQELSKEMTKAGIMEELVN 361
SV+M + +Q +++R+AG+LQKSTEVMK+M SL+K+PEIQ TM+ELSKEM KAGI+EE++
Sbjct: 86 SVLMGMKNQLAVLRVAGSLQKSTEVMKAMQSLVKIPEIQATMRELSKEMMKAGIIEEMLE 145
Query: 362 DTLXXXXXXXXXXXXXXXXXVDKILFDLTAGAMGAAPDAVRDTLPSGTPVAKGASS--SV 535
DT +D+ILF++TAGA+G AP V D LP P A+S
Sbjct: 146 DTF-ESMDDQEEMEEAAEMEIDRILFEITAGALGKAPSKVTDALPEPEPAGAMAASEEGE 204
Query: 536 PVEDDEDFDEMKARLEALRS 595
ED+ED + M++RL LRS
Sbjct: 205 EEEDEEDLEAMQSRLATLRS 224
>sp|Q4R574|CHMP3_MACFA Charged multivesicular body protein 3 (Chromatin modifying protein
3) (Vacuolar protein sorting 24)
Length = 222
Score = 171 bits (434), Expect = 1e-42
Identities = 90/198 (45%), Positives = 132/198 (66%)
Frame = +2
Query: 2 EERKLDRDINSIDRSLKQQELEIKKYAKQGNLDAAKILAKELINAKKSISRLYSAKAQMN 181
E R +DR I I R ++ + +K AK+G D +LAKE+I ++K++S+LY++KA MN
Sbjct: 26 EMRVVDRQIRDIQREEEKVKRSVKDAAKKGQKDVCVVLAKEMIRSRKAVSKLYASKAHMN 85
Query: 182 SVVMNLNHQASLVRMAGTLQKSTEVMKSMSSLIKVPEIQKTMQELSKEMTKAGIMEELVN 361
SV+M + +Q +++R+AG+LQKSTEVMK+M SL+K+PEI+ TM+ELSKEM KAGI+EE++
Sbjct: 86 SVLMGMKNQLAVLRVAGSLQKSTEVMKAMQSLVKIPEIRATMRELSKEMMKAGIIEEMLE 145
Query: 362 DTLXXXXXXXXXXXXXXXXXVDKILFDLTAGAMGAAPDAVRDTLPSGTPVAKGASSSVPV 541
DT +D+ILF++TAGA+G AP V D LP P A+S
Sbjct: 146 DTF-ESMDDQEEMEEAAEMEIDRILFEITAGALGKAPSKVTDALPEPEPSGAMAASDEEE 204
Query: 542 EDDEDFDEMKARLEALRS 595
E++E + M++RL LRS
Sbjct: 205 EEEEALEAMQSRLATLRS 222
>sp|Q58CS7|CHMP3_BOVIN Charged multivesicular body protein 3 (Chromatin modifying protein
3) (Vacuolar protein sorting 24)
Length = 222
Score = 171 bits (433), Expect = 2e-42
Identities = 90/198 (45%), Positives = 132/198 (66%)
Frame = +2
Query: 2 EERKLDRDINSIDRSLKQQELEIKKYAKQGNLDAAKILAKELINAKKSISRLYSAKAQMN 181
E R +DR I I R ++ + +K AK+G D +LAKE+I ++K++S+LY++KA MN
Sbjct: 26 EMRVVDRQIRDIQREEEKVKRSVKDAAKKGQKDVCVVLAKEMIRSRKAVSKLYASKAHMN 85
Query: 182 SVVMNLNHQASLVRMAGTLQKSTEVMKSMSSLIKVPEIQKTMQELSKEMTKAGIMEELVN 361
SV+M + +Q +++R+AG+LQKSTEVMK+M SL+K+PEIQ TM+ELSKEM KAGI+EE++
Sbjct: 86 SVLMGMKNQLAVLRVAGSLQKSTEVMKAMQSLVKIPEIQATMRELSKEMMKAGIIEEMLE 145
Query: 362 DTLXXXXXXXXXXXXXXXXXVDKILFDLTAGAMGAAPDAVRDTLPSGTPVAKGASSSVPV 541
DT +D+ILF++TAGA+ AP V D LP P+ A+S
Sbjct: 146 DTF-ESMDDQEEMEEAAEMEIDRILFEITAGALXKAPSKVTDALPEPEPLGAMAASEDEE 204
Query: 542 EDDEDFDEMKARLEALRS 595
E++E + M++RL LRS
Sbjct: 205 EEEEALEAMQSRLATLRS 222
>sp|Q6NXD2|CHM2B_BRARE Charged multivesicular body protein 2b (Chromatin modifying protein
2b) (CHMP2b)
Length = 214
Score = 94.7 bits (234), Expect = 2e-19
Identities = 60/194 (30%), Positives = 104/194 (53%), Gaps = 4/194 (2%)
Frame = +2
Query: 5 ERKLDRDINSIDRSLKQQELEIKKYAKQGNLDAAKILAKELINAKKSISRLYSAKAQMNS 184
+R++ RD ++++ KQ E+EIKK AK GN DA K+LAK+L+ +K +R Y+ +++ S
Sbjct: 25 QRQIARDRTALEKQEKQLEMEIKKMAKTGNRDACKVLAKQLVQVRKQKTRTYAVSSKVTS 84
Query: 185 VVMNLNHQASLVRMAGTLQKSTEVMKSMSSLIKVPEIQKTMQELSKEMTKAGIMEELVND 364
+ S ++MAG + +T+ M++++ + + +T+Q KE K + EE++ND
Sbjct: 85 MSTQTKLMNSQMKMAGAMATTTKTMQAVNKKMDPKKTMQTLQNFQKETAKMDMTEEMMND 144
Query: 365 TLXXXXXXXXXXXXXXXXXVDKILFDL---TAGAMGAAPDAVRDTLPSGTPVAKGASSSV 535
TL V+++L ++ +G M AP A R T + T A G S
Sbjct: 145 TL-DEIFEDSGDEEESQDIVNQVLDEIGIEISGKMAHAPSAARKTPSAATAKADGIS--- 200
Query: 536 PVEDDEDFD-EMKA 574
DED + ++KA
Sbjct: 201 ----DEDIERQLKA 210
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 56,324,115
Number of Sequences: 369166
Number of extensions: 871995
Number of successful extensions: 3398
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 3308
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3380
length of database: 68,354,980
effective HSP length: 107
effective length of database: 48,588,335
effective search space used: 5782011865
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)