Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= DrC_02958
(884 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q26474|LACH_SCHAM Lachesin precursor 80 1e-14
sp|P15364|AMAL_DROME Amalgam protein precursor 72 3e-12
sp|Q24372|LACH_DROME Lachesin precursor 68 3e-11
sp|P35969|VGFR1_MOUSE Vascular endothelial growth factor re... 61 5e-09
sp|P53767|VGFR1_RAT Vascular endothelial growth factor rece... 60 1e-08
sp|P17948|VGFR1_HUMAN Vascular endothelial growth factor re... 59 2e-08
sp|Q810U3|NFASC_MOUSE Neurofascin precursor 58 3e-08
sp|Q98892|OBCAM_CHICK Opioid-binding protein/cell adhesion ... 58 3e-08
sp|P97685|NFASC_RAT Neurofascin precursor 58 4e-08
sp|O94856|NFASC_HUMAN Neurofascin precursor 57 5e-08
>sp|Q26474|LACH_SCHAM Lachesin precursor
Length = 349
Score = 79.7 bits (195), Expect = 1e-14
Identities = 54/164 (32%), Positives = 87/164 (53%), Gaps = 3/164 (1%)
Frame = +2
Query: 293 YQLVVRDVIDSDSKRYQCKIDLAGFAESMKPFAIGLIILQKAPYITP--IQSQIVEEGKA 466
Y L ++D+ ++D+ YQC++ + + K A + +++ P I+ +S +V EG+A
Sbjct: 93 YTLQIKDIQETDAGFYQCQVIIG---LNNKITAEVDLQVRRPPVISDNSTRSLVVSEGQA 149
Query: 467 LQLDCKANGSPPPRVSWVKANGQAFPLPGSPQRVQNTTLYLPKITRYDRGVFRCHAVNNV 646
++L+C A G P PRVSW + N P GS R L + +I + DRG + C A N V
Sbjct: 150 VRLECYAGGYPAPRVSWRRENNAILPTGGSIYR--GNVLKISRIGKEDRGTYYCVAENGV 207
Query: 647 GLAGEYDVMVEVTFKPRVRQAR-RMGAYAQMANQNYEIMIECIV 775
G ++ VEV F P + R R+G Q Y++ +EC V
Sbjct: 208 GKGARRNIAVEVEFPPVITVPRPRLGQALQ-----YDMDLECHV 246
Score = 33.5 bits (75), Expect = 0.81
Identities = 34/152 (22%), Positives = 63/152 (41%), Gaps = 19/152 (12%)
Frame = +2
Query: 398 LIILQKAPYITPI-QSQIVEEGKALQLDCKANGSPPPRVSWVKA--NGQAFPLP---GSP 559
++ Q+ P I+ I Q QI + G ++L+C + V W+K N Q PLP GS
Sbjct: 15 VVYAQRTPTISYISQEQIKDIGGTVELECSVQYAQDYPVLWMKVDRNRQVDPLPISTGSS 74
Query: 560 QRVQNT-------------TLYLPKITRYDRGVFRCHAVNNVGLAGEYDVMVEVTFKPRV 700
++++ TL + I D G ++C + +GL + V++ + R
Sbjct: 75 LIIRDSRFALRYDTASSTYTLQIKDIQETDAGFYQCQVI--IGLNNKITAEVDLQVR-RP 131
Query: 701 RQARRMGAYAQMANQNYEIMIECIVNGLSRSR 796
+ + ++ + +EC G R
Sbjct: 132 PVISDNSTRSLVVSEGQAVRLECYAGGYPAPR 163
Score = 33.5 bits (75), Expect = 0.81
Identities = 23/79 (29%), Positives = 38/79 (48%), Gaps = 11/79 (13%)
Frame = +2
Query: 458 GKALQ----LDCKANGSPPPRVSWVK-----ANGQAFPLP--GSPQRVQNTTLYLPKITR 604
G+ALQ L+C PPP ++W+K +N Q + + + +TT + I +
Sbjct: 233 GQALQYDMDLECHVEAYPPPAITWLKDETVLSNNQHYSISHFATADEFTDTTRVI-TIEK 291
Query: 605 YDRGVFRCHAVNNVGLAGE 661
G ++C A N +G A E
Sbjct: 292 RQYGKYQCKAANKLGEARE 310
>sp|P15364|AMAL_DROME Amalgam protein precursor
Length = 333
Score = 71.6 bits (174), Expect = 3e-12
Identities = 48/167 (28%), Positives = 83/167 (49%), Gaps = 4/167 (2%)
Frame = +2
Query: 293 YQLVVRDVIDSDSKRYQCKIDLAGFAESMKPFAIGL----IILQKAPYITPIQSQIVEEG 460
Y ++++ SD Y+C++ ++ + K ++ + +I + P +S +V EG
Sbjct: 100 YTFRIQNIEVSDMGPYECQVLVSATEKVTKKLSLQIKTPPVIAENTP-----KSTLVTEG 154
Query: 461 KALQLDCKANGSPPPRVSWVKANGQAFPLPGSPQRVQNTTLYLPKITRYDRGVFRCHAVN 640
+ L+L C ANG P P +SW + + P G + TL + + R DRG + C A N
Sbjct: 155 QNLELTCHANGFPKPTISWAREHNAVMPAGG--HLLAEPTLRIRSVHRMDRGGYYCIAQN 212
Query: 641 NVGLAGEYDVMVEVTFKPRVRQARRMGAYAQMANQNYEIMIECIVNG 781
G + + VEV F+P++ A + AQM + + E +EC V G
Sbjct: 213 GEGQPDKRLIRVEVEFRPQI--AVQRPKIAQMVSHSAE--LECSVQG 255
Score = 30.8 bits (68), Expect = 5.2
Identities = 44/174 (25%), Positives = 67/174 (38%), Gaps = 11/174 (6%)
Frame = +2
Query: 167 GTTLELPVRKDTNGNDKYIVNFIHKRPSYVPTMPGQSQDVWNYQLVVRDVIDSDSKRYQC 346
G LEL NG K +++ + + MP + L +R V D Y C
Sbjct: 154 GQNLELTCH--ANGFPKPTISWAREHNA---VMPAGGHLLAEPTLRIRSVHRMDRGGYYC 208
Query: 347 KIDLAGFAESMKPFAIGLIILQKAPYITPIQSQIVEE-GKALQLDCKANGSPPPRVSWVK 523
+A E + + ++ P I + +I + + +L+C G P P V W K
Sbjct: 209 ---IAQNGEGQPDKRLIRVEVEFRPQIAVQRPKIAQMVSHSAELECSVQGYPAPTVVWHK 265
Query: 524 ANGQAFPLPGS-PQRVQNT---------TLYLPKITRYDRGVFRCHAVNNVGLA 655
NG PL S V NT L + + D G + C+A N +G A
Sbjct: 266 -NG--VPLQSSRHHEVANTASSSGTTTSVLRIDSVGEEDFGDYYCNATNKLGHA 316
>sp|Q24372|LACH_DROME Lachesin precursor
Length = 359
Score = 68.2 bits (165), Expect = 3e-11
Identities = 45/162 (27%), Positives = 80/162 (49%), Gaps = 3/162 (1%)
Frame = +2
Query: 293 YQLVVRDVIDSDSKRYQCKIDLAGFAESMKPFAIGLIILQKAPYITP--IQSQIVEEGKA 466
Y+L ++D+ ++D+ Y C++ ++ K A + +++ P I+ QS + EG
Sbjct: 96 YKLQIKDIQETDAGTYTCQVVISTVH---KVSAEVKLSVRRPPVISDNSTQSVVASEGSE 152
Query: 467 LQLDCKANGSPPPRVSWVKANGQAFPLPGSPQRVQNTTLYLPKITRYDRGVFRCHAVNNV 646
+Q++C A+G P P ++W + N LP TL + + + DRG + C A N V
Sbjct: 153 VQMECYASGYPTPTITWRRENNAI--LPTDSATYVGNTLRIKSVKKEDRGTYYCVADNGV 210
Query: 647 GLAGEYDVMVEVTFKPRVRQAR-RMGAYAQMANQNYEIMIEC 769
++ VEV F P + R R+G Q Y++ +EC
Sbjct: 211 SKGDRRNINVEVEFAPVITVPRPRLGQALQ-----YDMDLEC 247
Score = 33.5 bits (75), Expect = 0.81
Identities = 34/142 (23%), Positives = 56/142 (39%), Gaps = 11/142 (7%)
Frame = +2
Query: 263 MPGQSQDVWNYQLVVRDVIDSDSKRYQCKIDLAGFAESMKPFAIGLIILQKAPYITPIQS 442
+P S L ++ V D Y C D + + + + AP IT +
Sbjct: 177 LPTDSATYVGNTLRIKSVKKEDRGTYYCVADNGVSKGDRRNINVEV---EFAPVITVPRP 233
Query: 443 QIVEEGKALQ----LDCKANGSPPPRVSWVK-----ANGQAFPLP--GSPQRVQNTTLYL 589
++ G+ALQ L+C PPP + W K AN Q + + + ++TL +
Sbjct: 234 RL---GQALQYDMDLECHIEAYPPPAIVWTKDDIQLANNQHYSISHFATADEYTDSTLRV 290
Query: 590 PKITRYDRGVFRCHAVNNVGLA 655
+ + G + C A N G A
Sbjct: 291 ITVEKRQYGDYVCKATNRFGEA 312
>sp|P35969|VGFR1_MOUSE Vascular endothelial growth factor receptor 1 precursor (VEGFR-1)
(Tyrosine-protein kinase receptor FLT) (FLT-1)
(Embryonic receptor kinase 2)
Length = 1333
Score = 60.8 bits (146), Expect = 5e-09
Identities = 37/118 (31%), Positives = 58/118 (49%), Gaps = 1/118 (0%)
Frame = +2
Query: 299 LVVRDVIDSDSKRYQCKIDLAGFAESMKPFAIGLIILQKAPYITPIQSQI-VEEGKALQL 475
LV+++V DS Y C+ E + L+ +AP++ S V + L
Sbjct: 622 LVIKNVSLEDSGTYACRARNIYTGEDILRKTEVLVRDSEAPHLLQNLSDYEVSISGSTTL 681
Query: 476 DCKANGSPPPRVSWVKANGQAFPLPGSPQRVQNTTLYLPKITRYDRGVFRCHAVNNVG 649
DC+A G P P+++W K N + PG N+TL++ ++T D GV+RC A N G
Sbjct: 682 DCQARGVPAPQITWFKNNHKIQQEPGIILGPGNSTLFIERVTEEDEGVYRCRATNQKG 739
Score = 30.0 bits (66), Expect = 8.9
Identities = 26/116 (22%), Positives = 47/116 (40%), Gaps = 4/116 (3%)
Frame = +2
Query: 281 DVWNYQLVVRDVIDSDSKRYQCKIDLAGFAESMKPFAIGLIILQKAPYITPIQSQIVEEG 460
+V++ L + +V D Y C++ S + F + + +K + Q V+E
Sbjct: 291 NVFHSVLKINNVESRDKGLYTCRVKSGS---SFQSFNTSVHVYEKGFISVKHRKQPVQET 347
Query: 461 KA----LQLDCKANGSPPPRVSWVKANGQAFPLPGSPQRVQNTTLYLPKITRYDRG 616
A +L K P P + W+K +G L + V +L + +T D G
Sbjct: 348 TAGRRSYRLSMKVKAFPSPEIVWLK-DGSPATLKSARYLVHGYSLIIKDVTTEDAG 402
>sp|P53767|VGFR1_RAT Vascular endothelial growth factor receptor 1 precursor (VEGFR-1)
(Tyrosine-protein kinase receptor FLT) (FLT-1)
Length = 1336
Score = 59.7 bits (143), Expect = 1e-08
Identities = 36/119 (30%), Positives = 58/119 (48%), Gaps = 1/119 (0%)
Frame = +2
Query: 299 LVVRDVIDSDSKRYQCKIDLAGFAESMKPFAIGLIILQKAPYITP-IQSQIVEEGKALQL 475
LV+++V DS Y C+ E + L+ +AP + + V + L
Sbjct: 621 LVIKNVSLEDSGTYACRARNIYTGEEILRKTEVLVRDLEAPLLLQNLSDHEVSISGSTTL 680
Query: 476 DCKANGSPPPRVSWVKANGQAFPLPGSPQRVQNTTLYLPKITRYDRGVFRCHAVNNVGL 652
DC+A G P P+++W K N + PG N+TL++ ++T D GV+RC A N G+
Sbjct: 681 DCQARGVPAPQITWFKNNHKIQQEPGIILGPGNSTLFIERVTEEDEGVYRCRATNQKGV 739
>sp|P17948|VGFR1_HUMAN Vascular endothelial growth factor receptor 1 precursor (VEGFR-1)
(Vascular permeability factor receptor)
(Tyrosine-protein kinase receptor FLT) (Flt-1)
(Tyrosine-protein kinase FRT) (Fms-like tyrosine kinase
1)
Length = 1338
Score = 58.9 bits (141), Expect = 2e-08
Identities = 36/118 (30%), Positives = 55/118 (46%), Gaps = 1/118 (0%)
Frame = +2
Query: 299 LVVRDVIDSDSKRYQCKIDLAGFAESMKPFAIGLIILQKAPYITP-IQSQIVEEGKALQL 475
L + +V DS Y C+ E + I Q+APY+ + V + L
Sbjct: 621 LTIMNVSLQDSGTYACRARNVYTGEEILQKKEITIRDQEAPYLLRNLSDHTVAISSSTTL 680
Query: 476 DCKANGSPPPRVSWVKANGQAFPLPGSPQRVQNTTLYLPKITRYDRGVFRCHAVNNVG 649
DC ANG P P+++W K N + PG ++TL++ ++T D GV+ C A N G
Sbjct: 681 DCHANGVPEPQITWFKNNHKIQQEPGIILGPGSSTLFIERVTEEDEGVYHCKATNQKG 738
>sp|Q810U3|NFASC_MOUSE Neurofascin precursor
Length = 1240
Score = 58.2 bits (139), Expect = 3e-08
Identities = 61/228 (26%), Positives = 94/228 (41%), Gaps = 3/228 (1%)
Frame = +2
Query: 101 ISETQKARATWYSMDEQKTIAWGTTLELPVRKDTNGNDKYIVNFIHKRPSYVPTMPGQSQ 280
IS KA W + +A G L R NGN K V ++ P ++
Sbjct: 329 ISVRVKAAPYWLDEPKNLILAPGEDGRLVCR--ANGNPKPTVQWMVNGEPLQSAPPNPNR 386
Query: 281 DVWNYQLVVRDVIDSDSKRYQCKIDLAGFAESMKPFAIGLIILQKAPYITPIQSQIVEE- 457
+V ++ RD S YQC F + +L P + ++Q++
Sbjct: 387 EVAGDTIIFRDTQISSRAVYQCNTSNEHGYLLANAF---VSVLDVPPRMLSARNQLIRVI 443
Query: 458 -GKALQLDCKANGSPPPRVSWVKANGQAFPLPGSPQRV-QNTTLYLPKITRYDRGVFRCH 631
+LDC GSP P + W K NGQ L G V +N +L + I + D+G++ C
Sbjct: 444 LYNRTRLDCPFFGSPIPTLRWFK-NGQGSNLDGGNYHVYENGSLEIKMIRKEDQGIYTCV 502
Query: 632 AVNNVGLAGEYDVMVEVTFKPRVRQARRMGAYAQMANQNYEIMIECIV 775
A N +G A E V +EV R+ + Q+A + + +EC V
Sbjct: 503 ATNILGKA-ENQVRLEVKDPTRIYRMPE----DQVAKRGTTVQLECRV 545
Score = 42.7 bits (99), Expect = 0.001
Identities = 40/148 (27%), Positives = 68/148 (45%), Gaps = 6/148 (4%)
Frame = +2
Query: 287 WNYQLVVRDVIDSDSKRYQCKIDLAGFAESMKPFAIGLIILQKAPYITPIQSQIVEEGKA 466
+N L + +V + DS Y C LA I + + ++ ++ I+ G+
Sbjct: 297 FNKALRITNVSEEDSGEYFC---LASNKMGSIRHTISVRVKAAPYWLDEPKNLILAPGED 353
Query: 467 LQLDCKANGSPPPRVSWVKANGQAFPLPGSP----QRVQNTTLYLPKITRYDRGVFRCHA 634
+L C+ANG+P P V W+ NG+ PL +P + V T+ R V++C+
Sbjct: 354 GRLVCRANGNPKPTVQWM-VNGE--PLQSAPPNPNREVAGDTIIFRDTQISSRAVYQCNT 410
Query: 635 VNNVG--LAGEYDVMVEVTFKPRVRQAR 712
N G LA + +++V PR+ AR
Sbjct: 411 SNEHGYLLANAFVSVLDV--PPRMLSAR 436
Score = 42.4 bits (98), Expect = 0.002
Identities = 24/72 (33%), Positives = 37/72 (51%), Gaps = 2/72 (2%)
Frame = +2
Query: 440 SQIVEEGKALQLDCKANGSPPPRVSWVKANGQAFPLPGSPQRVQ--NTTLYLPKITRYDR 613
SQ+V G L L+C A+G P P ++W K G LP + + + N L + ++ D
Sbjct: 255 SQMVLRGMDLLLECIASGVPTPDIAWYKKGGD---LPSNKAKFENFNKALRITNVSEEDS 311
Query: 614 GVFRCHAVNNVG 649
G + C A N +G
Sbjct: 312 GEYFCLASNKMG 323
Score = 33.9 bits (76), Expect = 0.62
Identities = 27/106 (25%), Positives = 51/106 (48%), Gaps = 10/106 (9%)
Frame = +2
Query: 407 LQKAPYITP--IQSQIVEEGKALQLDCKANGSPPPRVSWVKANGQAFPLPGSPQ---RVQ 571
L + P IT ++ IV+ + ++C+A G+P P W + N + F + P+ R +
Sbjct: 37 LTQPPTITKQSVKDHIVDPRDNILIECEAKGNPAPSFHWTR-NSRFFNIAKDPRVSMRRR 95
Query: 572 NTTLYLP-----KITRYDRGVFRCHAVNNVGLAGEYDVMVEVTFKP 694
+ TL + + Y+ G ++C A N G A + ++V+ P
Sbjct: 96 SGTLVIDFRSGGRPEEYE-GEYQCFARNKFGTALSNRIRLQVSKSP 140
>sp|Q98892|OBCAM_CHICK Opioid-binding protein/cell adhesion molecule homolog precursor
(Neurite inhibitor GP55-A) (OBCAM protein gamma isoform)
Length = 337
Score = 58.2 bits (139), Expect = 3e-08
Identities = 42/145 (28%), Positives = 65/145 (44%), Gaps = 1/145 (0%)
Frame = +2
Query: 293 YQLVVRDVIDSDSKRYQCKIDLAGFAESMKPFAIGLIILQKAPYITPIQSQI-VEEGKAL 469
Y + + +V D Y C + ++ + +I+Q P I I S I V EG ++
Sbjct: 91 YSIKIHNVDVYDEGPYTCSVQTDNHPKTSRVH----LIVQVPPQIVNISSDITVNEGSSV 146
Query: 470 QLDCKANGSPPPRVSWVKANGQAFPLPGSPQRVQNTTLYLPKITRYDRGVFRCHAVNNVG 649
L C A G P P V+W +G+ G ++ L + ITR G + C AVN+V
Sbjct: 147 TLMCLAFGRPEPTVTWRHLSGK-----GQGFVSEDEYLEITGITREQSGEYECSAVNDVA 201
Query: 650 LAGEYDVMVEVTFKPRVRQARRMGA 724
+ V V V + P + A+ GA
Sbjct: 202 VPDVRKVKVTVNYPPYISNAKNTGA 226
>sp|P97685|NFASC_RAT Neurofascin precursor
Length = 1240
Score = 57.8 bits (138), Expect = 4e-08
Identities = 61/228 (26%), Positives = 94/228 (41%), Gaps = 3/228 (1%)
Frame = +2
Query: 101 ISETQKARATWYSMDEQKTIAWGTTLELPVRKDTNGNDKYIVNFIHKRPSYVPTMPGQSQ 280
IS KA W + +A G L R NGN K V ++ P ++
Sbjct: 329 ISVRVKAAPYWLDEPKNLILAPGEDGRLVCR--ANGNPKPTVQWLVNGDPLQSAPPNPNR 386
Query: 281 DVWNYQLVVRDVIDSDSKRYQCKIDLAGFAESMKPFAIGLIILQKAPYITPIQSQIVEE- 457
+V ++ RD S YQC F + +L P + ++Q++
Sbjct: 387 EVAGDTIIFRDTQISSRAVYQCNTSNEHGYLLANAF---VSVLDVPPRMLSPRNQLIRVI 443
Query: 458 -GKALQLDCKANGSPPPRVSWVKANGQAFPLPGSPQRV-QNTTLYLPKITRYDRGVFRCH 631
+LDC GSP P + W K NGQ L G V +N +L + I + D+G++ C
Sbjct: 444 LYNRTRLDCPFFGSPIPTLRWFK-NGQGSNLDGGNYHVYENGSLEIKMIRKEDQGIYTCV 502
Query: 632 AVNNVGLAGEYDVMVEVTFKPRVRQARRMGAYAQMANQNYEIMIECIV 775
A N +G A E V +EV R+ + Q+A + + +EC V
Sbjct: 503 ATNILGKA-ENQVRLEVKDPTRIYRMPE----DQVAKRGTTVQLECRV 545
Score = 42.4 bits (98), Expect = 0.002
Identities = 34/124 (27%), Positives = 54/124 (43%), Gaps = 10/124 (8%)
Frame = +2
Query: 440 SQIVEEGKALQLDCKANGSPPPRVSWVKANGQAFPLPGSPQRVQ--NTTLYLPKITRYDR 613
SQ+V G L L+C A+G P P ++W K G LP + + N L + ++ D
Sbjct: 255 SQMVLRGMDLLLECIASGVPTPDIAWYKKGGD---LPSDKAKFENFNKALRITNVSEEDS 311
Query: 614 GVFRCHAVNNVGLAGEYDVMVEVTFKP--------RVRQARRMGAYAQMANQNYEIMIEC 769
G + C A N +G + + + V V P + G AN N + ++
Sbjct: 312 GEYFCLASNKMG-SIRHTISVRVKAAPYWLDEPKNLILAPGEDGRLVCRANGNPKPTVQW 370
Query: 770 IVNG 781
+VNG
Sbjct: 371 LVNG 374
Score = 41.2 bits (95), Expect = 0.004
Identities = 37/145 (25%), Positives = 63/145 (43%), Gaps = 3/145 (2%)
Frame = +2
Query: 287 WNYQLVVRDVIDSDSKRYQCKIDLAGFAESMKPFAIGLIILQKAPYITPIQSQIVEEGKA 466
+N L + +V + DS Y C LA I + + ++ ++ I+ G+
Sbjct: 297 FNKALRITNVSEEDSGEYFC---LASNKMGSIRHTISVRVKAAPYWLDEPKNLILAPGED 353
Query: 467 LQLDCKANGSPPPRVSWVKANGQAFPLPGSPQR-VQNTTLYLPKITRYDRGVFRCHAVNN 643
+L C+ANG+P P V W+ P +P R V T+ R V++C+ N
Sbjct: 354 GRLVCRANGNPKPTVQWLVNGDPLQSAPPNPNREVAGDTIIFRDTQISSRAVYQCNTSNE 413
Query: 644 VG--LAGEYDVMVEVTFKPRVRQAR 712
G LA + +++V PR+ R
Sbjct: 414 HGYLLANAFVSVLDV--PPRMLSPR 436
Score = 33.9 bits (76), Expect = 0.62
Identities = 27/106 (25%), Positives = 51/106 (48%), Gaps = 10/106 (9%)
Frame = +2
Query: 407 LQKAPYITP--IQSQIVEEGKALQLDCKANGSPPPRVSWVKANGQAFPLPGSPQ---RVQ 571
L + P IT ++ IV+ + ++C+A G+P P W + N + F + P+ R +
Sbjct: 37 LTQPPTITKQSVKDHIVDPRDNILIECEAKGNPAPSFHWTR-NSRFFNIAKDPRVSMRRR 95
Query: 572 NTTLYLP-----KITRYDRGVFRCHAVNNVGLAGEYDVMVEVTFKP 694
+ TL + + Y+ G ++C A N G A + ++V+ P
Sbjct: 96 SGTLVIDFRSGGRPEEYE-GEYQCFARNKFGTALSNRIRLQVSKSP 140
>sp|O94856|NFASC_HUMAN Neurofascin precursor
Length = 1240
Score = 57.4 bits (137), Expect = 5e-08
Identities = 61/228 (26%), Positives = 94/228 (41%), Gaps = 3/228 (1%)
Frame = +2
Query: 101 ISETQKARATWYSMDEQKTIAWGTTLELPVRKDTNGNDKYIVNFIHKRPSYVPTMPGQSQ 280
IS KA W + +A G L R NGN K V ++ P ++
Sbjct: 329 ISVRVKAAPYWLDEPKNLILAPGEDGRLVCR--ANGNPKPTVQWMVNGEPLQSAPPNPNR 386
Query: 281 DVWNYQLVVRDVIDSDSKRYQCKIDLAGFAESMKPFAIGLIILQKAPYITPIQSQIVEE- 457
+V ++ RD S YQC F + +L P + ++Q++
Sbjct: 387 EVAGDTIIFRDTQISSRAVYQCNTSNEHGYLLANAF---VSVLDVPPRMLSPRNQLIRVI 443
Query: 458 -GKALQLDCKANGSPPPRVSWVKANGQAFPLPGSPQRV-QNTTLYLPKITRYDRGVFRCH 631
+LDC GSP P + W K NGQ L G V +N +L + I + D+G++ C
Sbjct: 444 LYNRTRLDCPFFGSPIPTLRWFK-NGQGSNLDGGNYHVYENGSLEIKMIRKEDQGIYTCV 502
Query: 632 AVNNVGLAGEYDVMVEVTFKPRVRQARRMGAYAQMANQNYEIMIECIV 775
A N +G A E V +EV R+ + Q+A + + +EC V
Sbjct: 503 ATNILGKA-ENQVRLEVKDPTRIYRMPE----DQVARRGTTVQLECRV 545
Score = 42.4 bits (98), Expect = 0.002
Identities = 33/139 (23%), Positives = 59/139 (42%), Gaps = 12/139 (8%)
Frame = +2
Query: 269 GQSQDVWNYQLVVRDVIDSDSKRYQC--KIDLAGFAESMKPFAIGLIILQKAPYITP--- 433
G + D++ ++++D+ Y C + + PF + ++ + TP
Sbjct: 192 GHNGDLYFSNVMLQDM----QTDYSCNARFHFTHTIQQKNPFTLKVLTTRGVAERTPSFM 247
Query: 434 -----IQSQIVEEGKALQLDCKANGSPPPRVSWVKANGQAFPLPGSPQRVQ--NTTLYLP 592
SQ+V G L L+C A+G P P ++W K G LP + + N L +
Sbjct: 248 YPQGTASSQMVLRGMDLLLECIASGVPTPDIAWYKKGGD---LPSDKAKFENFNKALRIT 304
Query: 593 KITRYDRGVFRCHAVNNVG 649
++ D G + C A N +G
Sbjct: 305 NVSEEDSGEYFCLASNKMG 323
Score = 40.8 bits (94), Expect = 0.005
Identities = 39/148 (26%), Positives = 67/148 (45%), Gaps = 6/148 (4%)
Frame = +2
Query: 287 WNYQLVVRDVIDSDSKRYQCKIDLAGFAESMKPFAIGLIILQKAPYITPIQSQIVEEGKA 466
+N L + +V + DS Y C LA I + + ++ ++ I+ G+
Sbjct: 297 FNKALRITNVSEEDSGEYFC---LASNKMGSIRHTISVRVKAAPYWLDEPKNLILAPGED 353
Query: 467 LQLDCKANGSPPPRVSWVKANGQAFPLPGSP----QRVQNTTLYLPKITRYDRGVFRCHA 634
+L C+ANG+P P V W+ NG+ PL +P + V T+ R V++C+
Sbjct: 354 GRLVCRANGNPKPTVQWM-VNGE--PLQSAPPNPNREVAGDTIIFRDTQISSRAVYQCNT 410
Query: 635 VNNVG--LAGEYDVMVEVTFKPRVRQAR 712
N G LA + +++V PR+ R
Sbjct: 411 SNEHGYLLANAFVSVLDV--PPRMLSPR 436
Score = 32.3 bits (72), Expect = 1.8
Identities = 27/106 (25%), Positives = 50/106 (47%), Gaps = 10/106 (9%)
Frame = +2
Query: 407 LQKAPYITP--IQSQIVEEGKALQLDCKANGSPPPRVSWVKANGQAFPLPGSPQ---RVQ 571
L + P IT + IV+ + ++C+A G+P P W + N + F + P+ R +
Sbjct: 37 LTQPPTITKQSAKDHIVDPRDNILIECEAKGNPAPSFHWTR-NSRFFNIAKDPRVSMRRR 95
Query: 572 NTTLYLP-----KITRYDRGVFRCHAVNNVGLAGEYDVMVEVTFKP 694
+ TL + + Y+ G ++C A N G A + ++V+ P
Sbjct: 96 SGTLVIDFRSGGRPEEYE-GEYQCFARNKFGTALSNRIRLQVSKSP 140
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 106,607,888
Number of Sequences: 369166
Number of extensions: 2264597
Number of successful extensions: 6576
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 5557
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 6413
length of database: 68,354,980
effective HSP length: 110
effective length of database: 48,034,130
effective search space used: 8838279920
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)