Planaria EST Database


DrC_02950

BLASTX 2.2.13 [Nov-27-2005]

Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= DrC_02950
         (855 letters)

Database: Non-redundant SwissProt sequences 
           184,735 sequences; 68,354,980 total letters



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

sp|Q13148|TADBP_HUMAN  TAR DNA-binding protein 43 (TDP-43)        189   6e-48
sp|Q921F2|TADBP_MOUSE  TAR DNA-binding protein 43 (TDP-43)        189   1e-47
sp|O43347|MSI1H_HUMAN  RNA-binding protein Musashi homolog 1...    79   2e-14
sp|Q920Q6|MSI2H_MOUSE  RNA-binding protein Musashi homolog 2...    78   4e-14
sp|Q8K3P4|MSI1H_RAT  RNA-binding protein Musashi homolog 1 (...    78   4e-14
sp|Q96DH6|MSI2H_HUMAN  RNA-binding protein Musashi homolog 2...    78   4e-14
sp|Q61474|MSI1H_MOUSE  RNA-binding protein Musashi homolog 1...    78   4e-14
sp|P51991|ROA3_HUMAN  Heterogeneous nuclear ribonucleoprotei...    77   5e-14
sp|Q8BG05|ROA3_MOUSE  Heterogeneous nuclear ribonucleoprotei...    77   5e-14
sp|P21522|ROA1_SCHAM  Heterogeneous nuclear ribonucleoprotei...    77   5e-14
>sp|Q13148|TADBP_HUMAN TAR DNA-binding protein 43 (TDP-43)
          Length = 414

 Score =  189 bits (481), Expect = 6e-48
 Identities = 111/282 (39%), Positives = 158/282 (56%), Gaps = 18/282 (6%)
 Frame = +1

Query: 1   DLKFICVFPKEIDNKRKCKEDYEISTPKTKRLETRKCTDLIVLNLGWKVDEEILRNYFSK 180
           +L ++  +PK  DNKRK  E    S  K KR   +K +DLIVL L WK  E+ L+ YFS 
Sbjct: 70  NLVYVVNYPK--DNKRKMDETDASSAVKVKRA-VQKTSDLIVLGLPWKTTEQDLKEYFST 126

Query: 181 FGELVLVQVKKDRETNHSKGYAFVRFADYDGQVLCLAEKHLIDGRWCAVKVPFSKSEADK 360
           FGE+++VQVKKD +T HSKG+ FVRF +Y+ QV  ++++H+IDGRWC  K+P SK   D+
Sbjct: 127 FGEVLMVQVKKDLKTGHSKGFGFVRFTEYETQVKVMSQRHMIDGRWCDCKLPNSKQSQDE 186

Query: 361 QEISKKIHVGYNSEEIEMEDLRKSFEEYGYVTDIFIPKPFRNFAFVTFDASDVAQQLIGR 540
              S+K+ VG  +E++  ++LR+ F +YG V D+FIPKPFR FAFVTF    +AQ L G 
Sbjct: 187 PLRSRKVFVGRCTEDMTEDELREFFSQYGDVMDVFIPKPFRAFAFVTFADDQIAQSLCGE 246

Query: 541 TVTLKGHALTIGSAVPKIS------------------GGKKGAQLAHGEQAAFSSNNRYN 666
            + +KG ++ I +A PK +                  G + G   + G  A   +N   N
Sbjct: 247 DLIIKGISVHISNAEPKHNSNRQLERSGRFGGNPGGFGNQGGFGNSRGGGAGLGNNQGSN 306

Query: 667 WGAAYEHAALKMAPYKSRQLRNSLAFGSYGGALMTTAGPNQS 792
            G      A  + P      + +L   S+G   M  +  NQS
Sbjct: 307 MGGGMNFGAFSINPAMMAAAQAALQ-SSWGMMGMLASQQNQS 347
>sp|Q921F2|TADBP_MOUSE TAR DNA-binding protein 43 (TDP-43)
          Length = 414

 Score =  189 bits (479), Expect = 1e-47
 Identities = 112/282 (39%), Positives = 159/282 (56%), Gaps = 18/282 (6%)
 Frame = +1

Query: 1   DLKFICVFPKEIDNKRKCKEDYEISTPKTKRLETRKCTDLIVLNLGWKVDEEILRNYFSK 180
           +L ++  +PK  DNKRK  E    S  K KR   +K +DLIVL L WK  E+ L++YFS 
Sbjct: 70  NLVYVVNYPK--DNKRKMDETDASSAVKVKRA-VQKTSDLIVLGLPWKTTEQDLKDYFST 126

Query: 181 FGELVLVQVKKDRETNHSKGYAFVRFADYDGQVLCLAEKHLIDGRWCAVKVPFSKSEADK 360
           FGE+++VQVKKD +T HSKG+ FVRF +Y+ QV  ++++H+IDGRWC  K+P SK   D+
Sbjct: 127 FGEVLMVQVKKDLKTGHSKGFGFVRFTEYETQVKVMSQRHMIDGRWCDCKLPNSKQSPDE 186

Query: 361 QEISKKIHVGYNSEEIEMEDLRKSFEEYGYVTDIFIPKPFRNFAFVTFDASDVAQQLIGR 540
              S+K+ VG  +E++  E+L++ F +YG V D+FIPKPFR FAFVTF    VAQ L G 
Sbjct: 187 PLRSRKVFVGRCTEDMTAEELQQFFCQYGEVVDVFIPKPFRAFAFVTFADDKVAQSLCGE 246

Query: 541 TVTLKGHALTIGSAVPKIS------------------GGKKGAQLAHGEQAAFSSNNRYN 666
            + +KG ++ I +A PK +                  G + G   + G  A   +N   N
Sbjct: 247 DLIIKGISVHISNAEPKHNSNRQLERSGRFGGNPGGFGNQGGFGNSRGGGAGLGNNQGGN 306

Query: 667 WGAAYEHAALKMAPYKSRQLRNSLAFGSYGGALMTTAGPNQS 792
            G      A  + P      + +L   S+G   M  +  NQS
Sbjct: 307 MGGGMNFGAFSINPAMMAAAQAALQ-SSWGMMGMLASQQNQS 347
>sp|O43347|MSI1H_HUMAN RNA-binding protein Musashi homolog 1 (Musashi-1)
          Length = 362

 Score = 78.6 bits (192), Expect = 2e-14
 Identities = 48/145 (33%), Positives = 76/145 (52%), Gaps = 7/145 (4%)
 Frame = +1

Query: 118 LIVLNLGWKVDEEILRNYFSKFGELVLVQVKKDRETNHSKGYAFVRFADYDGQVLCLAE- 294
           + +  L W+  +E LR YF +FGE+    V +D  T  S+G+ FV F D  G    LA+ 
Sbjct: 22  MFIGGLSWQTTQEGLREYFGQFGEVKECLVMRDPLTKRSRGFGFVTFMDQAGVDKVLAQS 81

Query: 295 KHLIDGRWCAVKVPFSKSEADKQEI-SKKIHVGYNSEEIEMEDLRKSFEEYGYVTDIFI- 468
           +H +D +    KV F +    K    +KKI VG  S    +ED+++ FE++G V D  + 
Sbjct: 82  RHELDSKTIDPKVAFPRRAQPKMVTRTKKIFVGGLSVNTTVEDVKQYFEQFGKVDDAMLM 141

Query: 469 ----PKPFRNFAFVTFDASDVAQQL 531
                   R F FVTF++ D+ +++
Sbjct: 142 FDKTTNRHRGFGFVTFESEDIVEKV 166
>sp|Q920Q6|MSI2H_MOUSE RNA-binding protein Musashi homolog 2 (Musashi-2)
          Length = 346

 Score = 77.8 bits (190), Expect = 4e-14
 Identities = 49/145 (33%), Positives = 74/145 (51%), Gaps = 7/145 (4%)
 Frame = +1

Query: 118 LIVLNLGWKVDEEILRNYFSKFGELVLVQVKKDRETNHSKGYAFVRFADYDGQVLCLAE- 294
           + +  L W+   + LR+YFSKFGE+    V +D  T  S+G+ FV FAD       L + 
Sbjct: 23  MFIGGLSWQTSPDSLRDYFSKFGEIRECMVMRDPTTKRSRGFGFVTFADPASVDKVLGQP 82

Query: 295 KHLIDGRWCAVKVPFSKSEADKQEI-SKKIHVGYNSEEIEMEDLRKSFEEYGYVTDIFI- 468
            H +D +    KV F +    K    +KKI VG  S    +ED+++ FE++G V D  + 
Sbjct: 83  HHELDSKTIDPKVAFPRRAQPKMVTRTKKIFVGGLSANTVVEDVKQYFEQFGKVEDAMLM 142

Query: 469 ----PKPFRNFAFVTFDASDVAQQL 531
                   R F FVTF+  DV +++
Sbjct: 143 FDKTTNRHRGFGFVTFENEDVVEKV 167
>sp|Q8K3P4|MSI1H_RAT RNA-binding protein Musashi homolog 1 (Musashi-1)
          Length = 362

 Score = 77.8 bits (190), Expect = 4e-14
 Identities = 48/145 (33%), Positives = 75/145 (51%), Gaps = 7/145 (4%)
 Frame = +1

Query: 118 LIVLNLGWKVDEEILRNYFSKFGELVLVQVKKDRETNHSKGYAFVRFADYDGQVLCLAE- 294
           + +  L W+  +E LR YF +FGE+    V +D  T  S+G+ FV F D  G    LA+ 
Sbjct: 22  MFIGGLSWQTTQEGLREYFGQFGEVKECLVMRDPLTKRSRGFGFVTFMDQAGVDKVLAQS 81

Query: 295 KHLIDGRWCAVKVPFSKSEADKQEI-SKKIHVGYNSEEIEMEDLRKSFEEYGYVTDIFI- 468
           +H +D +    KV F +    K    +KKI VG  S    +ED++  FE++G V D  + 
Sbjct: 82  RHELDSKTIDPKVAFPRRAQPKMVTRTKKIFVGGLSVNTTVEDVKHYFEQFGKVDDAMLM 141

Query: 469 ----PKPFRNFAFVTFDASDVAQQL 531
                   R F FVTF++ D+ +++
Sbjct: 142 FDKTTNRHRGFGFVTFESEDIVEKV 166
>sp|Q96DH6|MSI2H_HUMAN RNA-binding protein Musashi homolog 2 (Musashi-2)
          Length = 328

 Score = 77.8 bits (190), Expect = 4e-14
 Identities = 49/145 (33%), Positives = 74/145 (51%), Gaps = 7/145 (4%)
 Frame = +1

Query: 118 LIVLNLGWKVDEEILRNYFSKFGELVLVQVKKDRETNHSKGYAFVRFADYDGQVLCLAE- 294
           + +  L W+   + LR+YFSKFGE+    V +D  T  S+G+ FV FAD       L + 
Sbjct: 23  MFIGGLSWQTSPDSLRDYFSKFGEIRECMVMRDPTTKRSRGFGFVTFADPASVDKVLGQP 82

Query: 295 KHLIDGRWCAVKVPFSKSEADKQEI-SKKIHVGYNSEEIEMEDLRKSFEEYGYVTDIFI- 468
            H +D +    KV F +    K    +KKI VG  S    +ED+++ FE++G V D  + 
Sbjct: 83  HHELDSKTIDPKVAFPRRAQPKMVTRTKKIFVGGLSANTVVEDVKQYFEQFGKVEDAMLM 142

Query: 469 ----PKPFRNFAFVTFDASDVAQQL 531
                   R F FVTF+  DV +++
Sbjct: 143 FDKTTNRHRGFGFVTFENEDVVEKV 167
>sp|Q61474|MSI1H_MOUSE RNA-binding protein Musashi homolog 1 (Musashi-1)
          Length = 362

 Score = 77.8 bits (190), Expect = 4e-14
 Identities = 48/145 (33%), Positives = 75/145 (51%), Gaps = 7/145 (4%)
 Frame = +1

Query: 118 LIVLNLGWKVDEEILRNYFSKFGELVLVQVKKDRETNHSKGYAFVRFADYDGQVLCLAE- 294
           + +  L W+  +E LR YF +FGE+    V +D  T  S+G+ FV F D  G    LA+ 
Sbjct: 22  MFIGGLSWQTTQEGLREYFGQFGEVKECLVMRDPLTKRSRGFGFVTFMDQAGVDKVLAQS 81

Query: 295 KHLIDGRWCAVKVPFSKSEADKQEI-SKKIHVGYNSEEIEMEDLRKSFEEYGYVTDIFI- 468
           +H +D +    KV F +    K    +KKI VG  S    +ED++  FE++G V D  + 
Sbjct: 82  RHELDSKTIDPKVAFPRRAQPKMVTRTKKIFVGGLSVNTTVEDVKHYFEQFGKVDDAMLM 141

Query: 469 ----PKPFRNFAFVTFDASDVAQQL 531
                   R F FVTF++ D+ +++
Sbjct: 142 FDKTTNRHRGFGFVTFESEDIVEKV 166
>sp|P51991|ROA3_HUMAN Heterogeneous nuclear ribonucleoprotein A3 (hnRNP A3)
          Length = 378

 Score = 77.4 bits (189), Expect = 5e-14
 Identities = 61/213 (28%), Positives = 99/213 (46%), Gaps = 11/213 (5%)
 Frame = +1

Query: 25  PKEIDNKRKCKEDYEISTPKTKRLETRKCTDLIVLNLGWKVDEEILRNYFSKFGELVLVQ 204
           P+    +R+ +   E   PK    E  +   L +  L ++  ++ LR +F K+G L    
Sbjct: 10  PQPDSGRRRRRRGEEGHDPK----EPEQLRKLFIGGLSFETTDDSLREHFEKWGTLTDCV 65

Query: 205 VKKDRETNHSKGYAFVRFADYD--GQVLCLAEKHLIDGRWCAVKVPFSKSEADKQEIS-- 372
           V +D +T  S+G+ FV ++  +     +C A  H +DGR    K   S+ ++ K      
Sbjct: 66  VMRDPQTKRSRGFGFVTYSCVEEVDAAMC-ARPHKVDGRVVEPKRAVSREDSVKPGAHLT 124

Query: 373 -KKIHVGYNSEEIEMEDLRKSFEEYGYVTDIFIPK-----PFRNFAFVTFDASDVAQQLI 534
            KKI VG   E+ E  +LR  FE+YG +  I + +       R FAFVTFD  D   +++
Sbjct: 125 VKKIFVGGIKEDTEEYNLRDYFEKYGKIETIEVMEDRQSGKKRGFAFVTFDDHDTVDKIV 184

Query: 535 GRTV-TLKGHALTIGSAVPKISGGKKGAQLAHG 630
            +   T+ GH   +  A+ K      G+Q   G
Sbjct: 185 VQKYHTINGHNCEVKKALSKQEMQSAGSQRGRG 217

 Score = 55.5 bits (132), Expect = 2e-07
 Identities = 36/117 (30%), Positives = 59/117 (50%), Gaps = 4/117 (3%)
 Frame = +1

Query: 13  ICVFPKEIDNK---RKCKEDYEISTPKTKRLETRKCTDLIVLNLGWKVDEEILRNYFSKF 183
           +C  P ++D +    K     E S      L  +K   + V  +    +E  LR+YF K+
Sbjct: 93  MCARPHKVDGRVVEPKRAVSREDSVKPGAHLTVKK---IFVGGIKEDTEEYNLRDYFEKY 149

Query: 184 GELVLVQVKKDRETNHSKGYAFVRFADYDGQVLCLAEK-HLIDGRWCAVKVPFSKSE 351
           G++  ++V +DR++   +G+AFV F D+D     + +K H I+G  C VK   SK E
Sbjct: 150 GKIETIEVMEDRQSGKKRGFAFVTFDDHDTVDKIVVQKYHTINGHNCEVKKALSKQE 206
>sp|Q8BG05|ROA3_MOUSE Heterogeneous nuclear ribonucleoprotein A3 (hnRNP A3)
 sp|Q6URK4|ROA3_RAT Heterogeneous nuclear ribonucleoprotein A3 (hnRNP A3)
          Length = 379

 Score = 77.4 bits (189), Expect = 5e-14
 Identities = 61/213 (28%), Positives = 99/213 (46%), Gaps = 11/213 (5%)
 Frame = +1

Query: 25  PKEIDNKRKCKEDYEISTPKTKRLETRKCTDLIVLNLGWKVDEEILRNYFSKFGELVLVQ 204
           P+    +R+ +   E   PK    E  +   L +  L ++  ++ LR +F K+G L    
Sbjct: 10  PQPDSGRRRRRRGEEGHDPK----EPEQLRKLFIGGLSFETTDDSLREHFEKWGTLTDCV 65

Query: 205 VKKDRETNHSKGYAFVRFADYD--GQVLCLAEKHLIDGRWCAVKVPFSKSEADKQEIS-- 372
           V +D +T  S+G+ FV ++  +     +C A  H +DGR    K   S+ ++ K      
Sbjct: 66  VMRDPQTKRSRGFGFVTYSCVEEVDAAMC-ARPHKVDGRVVEPKRAVSREDSVKPGAHLT 124

Query: 373 -KKIHVGYNSEEIEMEDLRKSFEEYGYVTDIFIPK-----PFRNFAFVTFDASDVAQQLI 534
            KKI VG   E+ E  +LR  FE+YG +  I + +       R FAFVTFD  D   +++
Sbjct: 125 VKKIFVGGIKEDTEEYNLRDYFEKYGKIETIEVMEDRQSGKKRGFAFVTFDDHDTVDKIV 184

Query: 535 GRTV-TLKGHALTIGSAVPKISGGKKGAQLAHG 630
            +   T+ GH   +  A+ K      G+Q   G
Sbjct: 185 VQKYHTINGHNCEVKKALSKQEMQSAGSQRGRG 217

 Score = 55.5 bits (132), Expect = 2e-07
 Identities = 36/117 (30%), Positives = 59/117 (50%), Gaps = 4/117 (3%)
 Frame = +1

Query: 13  ICVFPKEIDNK---RKCKEDYEISTPKTKRLETRKCTDLIVLNLGWKVDEEILRNYFSKF 183
           +C  P ++D +    K     E S      L  +K   + V  +    +E  LR+YF K+
Sbjct: 93  MCARPHKVDGRVVEPKRAVSREDSVKPGAHLTVKK---IFVGGIKEDTEEYNLRDYFEKY 149

Query: 184 GELVLVQVKKDRETNHSKGYAFVRFADYDGQVLCLAEK-HLIDGRWCAVKVPFSKSE 351
           G++  ++V +DR++   +G+AFV F D+D     + +K H I+G  C VK   SK E
Sbjct: 150 GKIETIEVMEDRQSGKKRGFAFVTFDDHDTVDKIVVQKYHTINGHNCEVKKALSKQE 206
>sp|P21522|ROA1_SCHAM Heterogeneous nuclear ribonucleoprotein A1, A2/B1 homolog
          Length = 342

 Score = 77.4 bits (189), Expect = 5e-14
 Identities = 57/180 (31%), Positives = 90/180 (50%), Gaps = 15/180 (8%)
 Frame = +1

Query: 118 LIVLNLGWKVDEEILRNYFSKFGELVLVQVKKDRETNHSKGYAFVRFADY----DGQVLC 285
           L +  L ++  +E L+ +F ++GE+V V V KD +T  S+G+ F+ ++      D Q   
Sbjct: 19  LFIGGLDYRTTDESLKQHFEQWGEIVDVVVMKDPKTKRSRGFGFITYSRAHMVDDAQ--- 75

Query: 286 LAEKHLIDGRWCAVKVPFSKSEADKQEIS---KKIHVGYNSEEIEMEDLRKSFEEYGYVT 456
            A  H +DGR    K    ++E  + E     KK+ VG   EE+E  DLR  F++YG V 
Sbjct: 76  NARPHKVDGRVVEPKRAVPRTEIGRPEAGATVKKLFVGGIKEEMEENDLRDYFKQYGTVV 135

Query: 457 DIFI-----PKPFRNFAFVTFDASDVAQQL-IGRTVTLKGHALTIGSAVPK--ISGGKKG 612
              I      +  R FAFV FD  D   ++ + R   ++G  + +  A+PK    GG+ G
Sbjct: 136 SAAIVVDKETRKKRGFAFVEFDDYDPVDKICLSRNHQIRGKHIDVKKALPKGDAPGGRGG 195
  Database: Non-redundant SwissProt sequences
    Posted date:  Dec 6, 2005  7:40 AM
  Number of letters in database: 68,354,980
  Number of sequences in database:  184,735
  
  Database: swissprot.01
    Posted date:  Dec 6, 2005  8:18 AM
  Number of letters in database: 66,202,850
  Number of sequences in database:  184,431
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 94,663,193
Number of Sequences: 369166
Number of extensions: 1963555
Number of successful extensions: 8908
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 7938
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 8770
length of database: 68,354,980
effective HSP length: 109
effective length of database: 48,218,865
effective search space used: 8438301375
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)