Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= DrC_02948
(360 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P62194|PRS8_BOVIN 26S protease regulatory subunit 8 (Pro... 224 6e-59
sp|O18413|PRS8_DROME 26S protease regulatory subunit 8 223 1e-58
sp|P46470|PRS8_XENLA 26S protease regulatory subunit 8 (SUG... 221 4e-58
sp|P54814|PRS8_MANSE 26S protease regulatory subunit 8 (18-... 219 2e-57
sp|Q25544|PRS8_NAEFO 26S protease regulatory subunit 8 homo... 213 1e-55
sp|P41836|PRS8_SCHPO 26S protease regulatory subunit 8 homo... 210 9e-55
sp|P34124|PRS8_DICDI 26S protease regulatory subunit 8 (TAT... 209 2e-54
sp|Q01939|PRS8_YEAST 26S protease regulatory subunit 8 homo... 199 1e-51
sp|O26824|PSMR_METTH Proteasome-activating nucleotidase (Pr... 146 2e-35
sp|Q8TX03|PSMR_METKA Proteasome-activating nucleotidase (Pr... 136 1e-32
>sp|P62194|PRS8_BOVIN 26S protease regulatory subunit 8 (Proteasome subunit p45)
(p45/SUG) (Proteasome 26S subunit ATPase 5)
sp|P62196|PRS8_MOUSE 26S protease regulatory subunit 8 (Proteasome subunit p45)
(p45/SUG) (Proteasome 26S subunit ATPase 5) (mSUG1)
sp|P62195|PRS8_HUMAN 26S protease regulatory subunit 8 (Proteasome subunit p45)
(p45/SUG) (Proteasome 26S subunit ATPase 5) (Thyroid
hormone receptor interacting protein 1) (TRIP1)
sp|P62198|PRS8_RAT 26S protease regulatory subunit 8 (Proteasome subunit p45)
(p45/SUG) (Proteasome 26S subunit ATPase 5) (Thyroid
hormone receptor interacting protein 1) (TRIP1)
sp|P62197|PRS8_PIG 26S protease regulatory subunit 8 (Proteasome subunit p45)
(p45/SUG) (Proteasome 26S subunit ATPase 5) (TAT-binding
protein homolog 10) (TBP10)
Length = 406
Score = 224 bits (570), Expect = 6e-59
Identities = 110/119 (92%), Positives = 116/119 (97%)
Frame = +3
Query: 3 IEMSQVTPNSRVALRNDSYMLHKILPSKVDPLVSLMMVEKVPDSTYEMVGGLDKQIKEIK 182
I+++ VTPN RVALRNDSY LHKILP+KVDPLVSLMMVEKVPDSTYEM+GGLDKQIKEIK
Sbjct: 103 IDINDVTPNCRVALRNDSYTLHKILPNKVDPLVSLMMVEKVPDSTYEMIGGLDKQIKEIK 162
Query: 183 EVIELPVKHPELFEALGIAQPKGVLLYGPPGTGKTLLARAVAHHTECTFIRVSGSELVQ 359
EVIELPVKHPELFEALGIAQPKGVLLYGPPGTGKTLLARAVAHHT+CTFIRVSGSELVQ
Sbjct: 163 EVIELPVKHPELFEALGIAQPKGVLLYGPPGTGKTLLARAVAHHTDCTFIRVSGSELVQ 221
>sp|O18413|PRS8_DROME 26S protease regulatory subunit 8
Length = 405
Score = 223 bits (567), Expect = 1e-58
Identities = 110/119 (92%), Positives = 116/119 (97%)
Frame = +3
Query: 3 IEMSQVTPNSRVALRNDSYMLHKILPSKVDPLVSLMMVEKVPDSTYEMVGGLDKQIKEIK 182
I+++ VTPN RVALRN+SY LHKILP+KVDPLVSLMMVEKVPDSTYEMVGGLDKQIKEIK
Sbjct: 102 IDINDVTPNCRVALRNESYTLHKILPNKVDPLVSLMMVEKVPDSTYEMVGGLDKQIKEIK 161
Query: 183 EVIELPVKHPELFEALGIAQPKGVLLYGPPGTGKTLLARAVAHHTECTFIRVSGSELVQ 359
EVIELPVKHPELF+ALGIAQPKGVLLYGPPGTGKTLLARAVAHHTECTFIRVSGSELVQ
Sbjct: 162 EVIELPVKHPELFDALGIAQPKGVLLYGPPGTGKTLLARAVAHHTECTFIRVSGSELVQ 220
>sp|P46470|PRS8_XENLA 26S protease regulatory subunit 8 (SUG1 homolog) (xSUG1)
Length = 461
Score = 221 bits (563), Expect = 4e-58
Identities = 109/119 (91%), Positives = 115/119 (96%)
Frame = +3
Query: 3 IEMSQVTPNSRVALRNDSYMLHKILPSKVDPLVSLMMVEKVPDSTYEMVGGLDKQIKEIK 182
I+++ VTPN RVALRNDSY LHKILP+KVDPLVSLMMVEKVPDSTYEM+GGLDKQIKEIK
Sbjct: 98 IDINDVTPNCRVALRNDSYTLHKILPNKVDPLVSLMMVEKVPDSTYEMIGGLDKQIKEIK 157
Query: 183 EVIELPVKHPELFEALGIAQPKGVLLYGPPGTGKTLLARAVAHHTECTFIRVSGSELVQ 359
EVIELPVKHPE FEALGIAQPKGVLLYGPPGTGKTLLARAVAHHT+CTFIRVSGSELVQ
Sbjct: 158 EVIELPVKHPEHFEALGIAQPKGVLLYGPPGTGKTLLARAVAHHTDCTFIRVSGSELVQ 216
>sp|P54814|PRS8_MANSE 26S protease regulatory subunit 8 (18-56 protein)
Length = 402
Score = 219 bits (558), Expect = 2e-57
Identities = 108/119 (90%), Positives = 115/119 (96%)
Frame = +3
Query: 3 IEMSQVTPNSRVALRNDSYMLHKILPSKVDPLVSLMMVEKVPDSTYEMVGGLDKQIKEIK 182
++++ VT N RVALRN+SY LHKILP+KVDPLVSLMMVEKVPDSTYEMVGGLDKQIKEIK
Sbjct: 99 VDINDVTANCRVALRNESYTLHKILPNKVDPLVSLMMVEKVPDSTYEMVGGLDKQIKEIK 158
Query: 183 EVIELPVKHPELFEALGIAQPKGVLLYGPPGTGKTLLARAVAHHTECTFIRVSGSELVQ 359
EVIELPVKHPELF+ALGIAQPKGVLLYGPPGTGKTLLARAVAHHTECTFIRVSGSELVQ
Sbjct: 159 EVIELPVKHPELFDALGIAQPKGVLLYGPPGTGKTLLARAVAHHTECTFIRVSGSELVQ 217
>sp|Q25544|PRS8_NAEFO 26S protease regulatory subunit 8 homolog (TAT-binding protein
homolog)
Length = 414
Score = 213 bits (542), Expect = 1e-55
Identities = 102/119 (85%), Positives = 113/119 (94%)
Frame = +3
Query: 3 IEMSQVTPNSRVALRNDSYMLHKILPSKVDPLVSLMMVEKVPDSTYEMVGGLDKQIKEIK 182
IE+ +TP RVALRNDSY LHKILP+K+DPLVSLM VEKVPD+TYEMVGGLD+QIKEIK
Sbjct: 110 IELKDLTPGVRVALRNDSYALHKILPNKIDPLVSLMKVEKVPDATYEMVGGLDEQIKEIK 169
Query: 183 EVIELPVKHPELFEALGIAQPKGVLLYGPPGTGKTLLARAVAHHTECTFIRVSGSELVQ 359
EVIELP+KHPELFE+LGIAQPKGV++YGPPGTGKTLLARAVAHHT+CTFIRVSGSELVQ
Sbjct: 170 EVIELPIKHPELFESLGIAQPKGVIMYGPPGTGKTLLARAVAHHTDCTFIRVSGSELVQ 228
>sp|P41836|PRS8_SCHPO 26S protease regulatory subunit 8 homolog (Protein let1)
Length = 403
Score = 210 bits (534), Expect = 9e-55
Identities = 102/119 (85%), Positives = 112/119 (94%)
Frame = +3
Query: 3 IEMSQVTPNSRVALRNDSYMLHKILPSKVDPLVSLMMVEKVPDSTYEMVGGLDKQIKEIK 182
I++ ++ PN RVALRNDSY L KILP+KVDPLVSLMMVEK+PDSTYEMVGGL+KQIKEIK
Sbjct: 99 IDIKEIKPNIRVALRNDSYQLIKILPNKVDPLVSLMMVEKIPDSTYEMVGGLEKQIKEIK 158
Query: 183 EVIELPVKHPELFEALGIAQPKGVLLYGPPGTGKTLLARAVAHHTECTFIRVSGSELVQ 359
EVIELPVKHPELFE+LGI QPKG+LLYGPPGTGKTLLARAVAHHT+C FIRVSGSELVQ
Sbjct: 159 EVIELPVKHPELFESLGIPQPKGILLYGPPGTGKTLLARAVAHHTDCKFIRVSGSELVQ 217
>sp|P34124|PRS8_DICDI 26S protease regulatory subunit 8 (TAT-binding protein homolog 10)
Length = 389
Score = 209 bits (531), Expect = 2e-54
Identities = 97/119 (81%), Positives = 116/119 (97%)
Frame = +3
Query: 3 IEMSQVTPNSRVALRNDSYMLHKILPSKVDPLVSLMMVEKVPDSTYEMVGGLDKQIKEIK 182
++++++TP++R AL+++SY LH+ILP+K+DPLVSLM VEK+PDSTY+MVGGLDKQIKEIK
Sbjct: 85 VDIAKLTPSTRAALKHESYTLHRILPNKIDPLVSLMKVEKIPDSTYDMVGGLDKQIKEIK 144
Query: 183 EVIELPVKHPELFEALGIAQPKGVLLYGPPGTGKTLLARAVAHHTECTFIRVSGSELVQ 359
EVIELP+KHPELFE+LGIAQPKGVLLYGPPGTGKTLLARAVAHHT+CTFIRVSGSELVQ
Sbjct: 145 EVIELPIKHPELFESLGIAQPKGVLLYGPPGTGKTLLARAVAHHTDCTFIRVSGSELVQ 203
>sp|Q01939|PRS8_YEAST 26S protease regulatory subunit 8 homolog (SUG1 protein) (CIM3
protein) (TAT-binding protein TBY1)
Length = 405
Score = 199 bits (507), Expect = 1e-51
Identities = 97/119 (81%), Positives = 108/119 (90%)
Frame = +3
Query: 3 IEMSQVTPNSRVALRNDSYMLHKILPSKVDPLVSLMMVEKVPDSTYEMVGGLDKQIKEIK 182
I + + + RV LR+DSYMLHK+L +K DPLVSLMMVEKVPDSTY+MVGGL KQIKEIK
Sbjct: 102 INVKDLKASQRVCLRSDSYMLHKVLENKADPLVSLMMVEKVPDSTYDMVGGLTKQIKEIK 161
Query: 183 EVIELPVKHPELFEALGIAQPKGVLLYGPPGTGKTLLARAVAHHTECTFIRVSGSELVQ 359
EVIELPVKHPELFE+LGIAQPKGV+LYGPPGTGKTLLARAVAHHT+C FIRVSG+ELVQ
Sbjct: 162 EVIELPVKHPELFESLGIAQPKGVILYGPPGTGKTLLARAVAHHTDCKFIRVSGAELVQ 220
>sp|O26824|PSMR_METTH Proteasome-activating nucleotidase (Proteasome regulatory subunit)
Length = 410
Score = 146 bits (368), Expect = 2e-35
Identities = 67/119 (56%), Positives = 92/119 (77%)
Frame = +3
Query: 3 IEMSQVTPNSRVALRNDSYMLHKILPSKVDPLVSLMMVEKVPDSTYEMVGGLDKQIKEIK 182
I+ Q+ P +RVAL ++ + +LPS+ DP+V+ M VE+ PD +YE +GGL++Q++E+K
Sbjct: 105 IDRKQLEPGARVALNQQTFSIVDVLPSEKDPVVTGMEVEEKPDVSYEQIGGLEEQVREVK 164
Query: 183 EVIELPVKHPELFEALGIAQPKGVLLYGPPGTGKTLLARAVAHHTECTFIRVSGSELVQ 359
E +ELP+K PELFE +GI PKGVLLYGPPGTGKTLLA+AVAH T TFI++ SE V+
Sbjct: 165 ETVELPLKKPELFEKIGIEPPKGVLLYGPPGTGKTLLAKAVAHETNATFIKIVASEFVR 223
>sp|Q8TX03|PSMR_METKA Proteasome-activating nucleotidase (Proteasome regulatory subunit)
Length = 436
Score = 136 bits (343), Expect = 1e-32
Identities = 64/119 (53%), Positives = 90/119 (75%)
Frame = +3
Query: 3 IEMSQVTPNSRVALRNDSYMLHKILPSKVDPLVSLMMVEKVPDSTYEMVGGLDKQIKEIK 182
++ +++ P + VAL S + +LPS+ D V M V++ PD +Y+ +GGLD+QI+EI+
Sbjct: 133 VDRNELEPGANVALNQQSMAVVDVLPSEKDSRVLAMEVDESPDVSYDDIGGLDEQIREIR 192
Query: 183 EVIELPVKHPELFEALGIAQPKGVLLYGPPGTGKTLLARAVAHHTECTFIRVSGSELVQ 359
EV+E P+K PELFE +G+ PKGVLLYGPPGTGKTLLA+AVA+H + TFIR++ ELVQ
Sbjct: 193 EVVEKPLKEPELFEKVGVEPPKGVLLYGPPGTGKTLLAKAVANHADATFIRLAAPELVQ 251
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 41,568,162
Number of Sequences: 369166
Number of extensions: 754293
Number of successful extensions: 5283
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 4934
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5249
length of database: 68,354,980
effective HSP length: 87
effective length of database: 52,283,035
effective search space used: 1673057120
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)