Planaria EST Database


DrC_02872

BLASTX 2.2.13 [Nov-27-2005]

Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= DrC_02872
         (532 letters)

Database: Non-redundant SwissProt sequences 
           184,735 sequences; 68,354,980 total letters



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

sp|P98083|SHC1_MOUSE  SHC transforming protein 1 (SH2 domain...    50   3e-06
sp|P29353|SHC1_HUMAN  SHC transforming protein 1 (SH2 domain...    49   8e-06
sp|P07332|FES_HUMAN  Proto-oncogene tyrosine-protein kinase ...    45   1e-04
sp|P18106|FPS_DROME  Tyrosine-protein kinase Fps85D (dFer)         43   4e-04
sp|P16879|FES_MOUSE  Proto-oncogene tyrosine-protein kinase ...    43   5e-04
sp|Q92529|SHC3_HUMAN  SHC transforming protein 3 (SH2 domain...    42   7e-04
sp|P16591|FER_HUMAN  Proto-oncogene tyrosine-protein kinase ...    42   0.001
sp|Q61120|SHC3_MOUSE  SHC transforming protein 3 (SH2 domain...    42   0.001
sp|O70143|SHC3_RAT  SHC transforming protein 3 (SH2 domain p...    42   0.001
sp|P14238|FES_FELCA  Proto-oncogene tyrosine-protein kinase ...    41   0.002
>sp|P98083|SHC1_MOUSE SHC transforming protein 1 (SH2 domain protein C1) (Src homology 2
           domain containing transforming protein C1)
          Length = 579

 Score = 50.1 bits (118), Expect = 3e-06
 Identities = 32/105 (30%), Positives = 48/105 (45%), Gaps = 1/105 (0%)
 Frame = +2

Query: 137 LKDSIWFHGVIGRTEAESRIFNNGEFLVRFSEDKTNKFVVSSKWNGXXXXXXXXXXXXXX 316
           L+   WFHG + R EAE+ +  NG+FLVR S     ++V++   +G              
Sbjct: 479 LQGEPWFHGKLSRREAEALLQLNGDFLVRESTTTPGQYVLTGLQSGQPKHLLLVDPEGVV 538

Query: 317 XXCLVYFINSKFKFPTVLELIKFHKDNQYP-LSDASEAVLYKPID 448
                       +F +V  LI +H DN  P +S  SE  L +P+D
Sbjct: 539 R-------TKDHRFESVSHLISYHMDNHLPIISAGSELCLQQPVD 576
>sp|P29353|SHC1_HUMAN SHC transforming protein 1 (SH2 domain protein C1) (Src homology 2
           domain containing transforming protein C1)
          Length = 583

 Score = 48.9 bits (115), Expect = 8e-06
 Identities = 31/105 (29%), Positives = 48/105 (45%), Gaps = 1/105 (0%)
 Frame = +2

Query: 137 LKDSIWFHGVIGRTEAESRIFNNGEFLVRFSEDKTNKFVVSSKWNGXXXXXXXXXXXXXX 316
           L+   WFHG + R EAE+ +  NG+FLVR S     ++V++   +G              
Sbjct: 483 LRGEPWFHGKLSRREAEALLQLNGDFLVRESTTTPGQYVLTGLQSGQPKHLLLVDPEGVV 542

Query: 317 XXCLVYFINSKFKFPTVLELIKFHKDNQYP-LSDASEAVLYKPID 448
                       +F +V  LI +H DN  P +S  SE  L +P++
Sbjct: 543 R-------TKDHRFESVSHLISYHMDNHLPIISAGSELCLQQPVE 580
>sp|P07332|FES_HUMAN Proto-oncogene tyrosine-protein kinase Fes/Fps (C-Fes)
          Length = 822

 Score = 45.1 bits (105), Expect = 1e-04
 Identities = 33/120 (27%), Positives = 56/120 (46%)
 Frame = +2

Query: 86  IDPKLLFDNEINKQMDLLKDSIWFHGVIGRTEAESRIFNNGEFLVRFSEDKTNKFVVSSK 265
           + P L    E+ K    L + +W+HG I R E    + ++G+FLVR S+ K  ++V+S  
Sbjct: 441 LPPPLQLIPEVQKP---LHEQLWYHGAIPRAEVAELLVHSGDFLVRESQGK-QEYVLSVL 496

Query: 266 WNGXXXXXXXXXXXXXXXXCLVYFINSKFKFPTVLELIKFHKDNQYPLSDASEAVLYKPI 445
           W+G                  +Y +  +  FP++  LI      Q PL+  S  VL++ +
Sbjct: 497 WDGLPRHFIIQSLDN------LYRLEGE-GFPSIPLLIDHLLSTQQPLTKKSGVVLHRAV 549
>sp|P18106|FPS_DROME Tyrosine-protein kinase Fps85D (dFer)
          Length = 1325

 Score = 43.1 bits (100), Expect = 4e-04
 Identities = 30/107 (28%), Positives = 52/107 (48%), Gaps = 4/107 (3%)
 Frame = +2

Query: 137  LKDSIWFHGVIGRTEAESRIFNNGEFLVRFS-EDKTNKFVVSSKWNGXXXXXXXXXXXXX 313
            L +  WFHGV+ R E    + N+G+FLVR +  ++ ++ V+S  WNG             
Sbjct: 955  LYEEEWFHGVLpreEVVRLLNNDGDFLVRETIRNEESQIVLSVCWNGHKHFIVQTTGEG- 1013

Query: 314  XXXCLVYFINSKFK---FPTVLELIKFHKDNQYPLSDASEAVLYKPI 445
                     N +F+   F ++ ELI     ++ P++  S A+L +P+
Sbjct: 1014 ---------NFRFEGPPFASIQELIMHQYHSELPVTVKSGAILRRPV 1051
>sp|P16879|FES_MOUSE Proto-oncogene tyrosine-protein kinase Fes/Fps (C-Fes)
          Length = 820

 Score = 42.7 bits (99), Expect = 5e-04
 Identities = 32/125 (25%), Positives = 58/125 (46%), Gaps = 5/125 (4%)
 Frame = +2

Query: 86  IDPKLLFDNEINKQMDLLKDSIWFHGVIGRTEAESRIFNNGEFLVRFSEDKTNKFVVSSK 265
           I P L    E+ K    L + +W+HG I   E    + + G+FLVR S+ K  ++V+S  
Sbjct: 439 IPPPLQLVPEVQKP---LYEQLWYHGAIPWAEVAELLTHTGDFLVRESQGK-QEYVLSVM 494

Query: 266 WNGXXXXXXXXXXXXXXXXCLVYFINSKFK-----FPTVLELIKFHKDNQYPLSDASEAV 430
           W+G                 ++  +++ ++     FP++  LI     +Q PL+  S  V
Sbjct: 495 WDGHPRHF------------IIQSLDNLYRLEGDGFPSIPLLITHLLSSQQPLTKKSGVV 542

Query: 431 LYKPI 445
           L++ +
Sbjct: 543 LFRAV 547
>sp|Q92529|SHC3_HUMAN SHC transforming protein 3 (SH2 domain protein C3) (Src homology 2
           domain containing transforming protein C3) (Neuronal
           Shc) (N-Shc) (Protein Rai)
          Length = 594

 Score = 42.4 bits (98), Expect = 7e-04
 Identities = 30/111 (27%), Positives = 50/111 (45%), Gaps = 2/111 (1%)
 Frame = +2

Query: 122 KQMDLLKDSIWFHGVIGRTEAESRIFNNGEFLVRFSEDKTNKFVVSSKWNGXXXXXXXXX 301
           K ++ L+   W+ G + R EAE  +  +G+FLVR S      FV++   NG         
Sbjct: 489 KMLEELQAETWYQGEMSRKEAEGLLEKDGDFLVRKSTTNPGSFVLTGMHNGQAKHLLLVD 548

Query: 302 XXXXXXXCLVYFINSKFK-FPTVLELIKFHKDNQYPL-SDASEAVLYKPID 448
                       I +K + F ++  LI  H ++  P+ S  SE  L +P++
Sbjct: 549 PEGT--------IRTKDRVFDSISHLINHHLESSLPIVSAGSELCLQQPVE 591
>sp|P16591|FER_HUMAN Proto-oncogene tyrosine-protein kinase FER (p94-FER) (c-FER)
          Length = 822

 Score = 42.0 bits (97), Expect = 0.001
 Identities = 27/108 (25%), Positives = 49/108 (45%), Gaps = 5/108 (4%)
 Frame = +2

Query: 137 LKDSIWFHGVIGRTEAESRIFNNGEFLVRFSEDKTNKFVVSSKWNGXXXXXXXXXXXXXX 316
           L +  W+HG I R EA+  +   G+FLVR S  K  ++V+S   +G              
Sbjct: 455 LAEQDWYHGAIPRIEAQELLKKQGDFLVRESHGKPGEYVLSVYSDGQRRHF--------- 505

Query: 317 XXCLVYFINSKFK-----FPTVLELIKFHKDNQYPLSDASEAVLYKPI 445
              ++ ++++ ++     F  + +LI  H   +  ++  S  VL  PI
Sbjct: 506 ---IIQYVDNMYRFEGTGFSNIPQLIDHHYTTKQVITKKSGVVLLNPI 550
>sp|Q61120|SHC3_MOUSE SHC transforming protein 3 (SH2 domain protein C3) (Src homology 2
           domain containing transforming protein C3) (Neuronal
           Shc) (N-Shc)
          Length = 474

 Score = 42.0 bits (97), Expect = 0.001
 Identities = 29/111 (26%), Positives = 51/111 (45%), Gaps = 2/111 (1%)
 Frame = +2

Query: 122 KQMDLLKDSIWFHGVIGRTEAESRIFNNGEFLVRFSEDKTNKFVVSSKWNGXXXXXXXXX 301
           + ++ L    W+ G + R EAE+ +  +G+FLVR S      FV++   NG         
Sbjct: 369 RMLEELNAEPWYQGEMSRKEAEALLREDGDFLVRKSTTNPGSFVLTGMHNGQAKHLLLVD 428

Query: 302 XXXXXXXCLVYFINSKFK-FPTVLELIKFHKDNQYPL-SDASEAVLYKPID 448
                       I +K + F ++  LI +H ++  P+ S  SE  L +P++
Sbjct: 429 PEGT--------IRTKDRVFDSISHLINYHLESSLPIVSAGSELCLQQPVE 471
>sp|O70143|SHC3_RAT SHC transforming protein 3 (SH2 domain protein C3) (Src homology 2
           domain containing transforming protein C3) (Neuronal
           Shc) (N-Shc)
          Length = 594

 Score = 42.0 bits (97), Expect = 0.001
 Identities = 29/111 (26%), Positives = 51/111 (45%), Gaps = 2/111 (1%)
 Frame = +2

Query: 122 KQMDLLKDSIWFHGVIGRTEAESRIFNNGEFLVRFSEDKTNKFVVSSKWNGXXXXXXXXX 301
           K ++ L    W+ G + R EAE+ +  +G+FLVR S      FV++   NG         
Sbjct: 489 KMLEELNAEPWYQGEMSRKEAEALLQEDGDFLVRKSTTNPGSFVLTGMHNGQAKHLLLVD 548

Query: 302 XXXXXXXCLVYFINSKFK-FPTVLELIKFHKDNQYPL-SDASEAVLYKPID 448
                       + +K + F ++  LI +H ++  P+ S  SE  L +P++
Sbjct: 549 PEGT--------VRTKDRVFDSISHLITYHLESSLPIVSAGSELCLRQPVE 591
>sp|P14238|FES_FELCA Proto-oncogene tyrosine-protein kinase FES/FPS (C-FES)
          Length = 820

 Score = 41.2 bits (95), Expect = 0.002
 Identities = 21/63 (33%), Positives = 36/63 (57%)
 Frame = +2

Query: 86  IDPKLLFDNEINKQMDLLKDSIWFHGVIGRTEAESRIFNNGEFLVRFSEDKTNKFVVSSK 265
           + P L    E+ K    L + +W+HG + R E    + ++G+FLVR S+ K  ++V+S  
Sbjct: 439 LPPPLQLVPEVQKP---LHEQLWYHGALPRAEVAELLTHSGDFLVRESQGK-QEYVLSVL 494

Query: 266 WNG 274
           W+G
Sbjct: 495 WDG 497
  Database: Non-redundant SwissProt sequences
    Posted date:  Dec 6, 2005  7:40 AM
  Number of letters in database: 68,354,980
  Number of sequences in database:  184,735
  
  Database: swissprot.01
    Posted date:  Dec 6, 2005  8:18 AM
  Number of letters in database: 66,202,850
  Number of sequences in database:  184,431
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 61,487,247
Number of Sequences: 369166
Number of extensions: 1182474
Number of successful extensions: 3258
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 3188
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3239
length of database: 68,354,980
effective HSP length: 103
effective length of database: 49,327,275
effective search space used: 3600891075
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)