Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= DrC_02846
(538 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q29504|UBE1_RABIT Ubiquitin-activating enzyme E1 224 1e-58
sp|P22314|UBE1_HUMAN Ubiquitin-activating enzyme E1 (A1S9 p... 221 9e-58
sp|Q02053|UBE1_MOUSE Ubiquitin-activating enzyme E1 1 221 9e-58
sp|O94609|UBA1_SCHPO Ubiquitin-activating enzyme E1 1 (Poly... 216 4e-56
sp|P22515|UBA1_YEAST Ubiquitin-activating enzyme E1 1 199 4e-51
sp|P31255|UBE1Y_MACRU Ubiquitin-activating enzyme E1 Y 174 9e-44
sp|P31252|UBE13_WHEAT Ubiquitin-activating enzyme E1 3 173 2e-43
sp|P20973|UBE11_WHEAT Ubiquitin-activating enzyme E1 1 171 1e-42
sp|P31251|UBE12_WHEAT Ubiquitin-activating enzyme E1 2 171 1e-42
sp|P31253|UBE1X_MOUSE Ubiquitin-activating enzyme E1 X 164 1e-40
>sp|Q29504|UBE1_RABIT Ubiquitin-activating enzyme E1
Length = 1058
Score = 224 bits (570), Expect = 1e-58
Identities = 108/182 (59%), Positives = 131/182 (71%), Gaps = 4/182 (2%)
Frame = +1
Query: 1 VEAGQYMDRRCVFYLKPLLESGTLGTKCNVQVVLPHLTESYSSSPDPPEKSIPVCTLKNF 180
V+A YMDRRCV+Y KPLLESGTLGTK NVQVV+P LTESYSSS DPPEKSIP+CTLKNF
Sbjct: 578 VDARMYMDRRCVYYRKPLLESGTLGTKGNVQVVIPFLTESYSSSQDPPEKSIPICTLKNF 637
Query: 181 PYTIEHTIQWARDLFEGLFSQPAASANQFLSDKQRFLDSVSKCHSSDTGEQVS----NIV 348
P IEHT+QWARD FEGLF QPA + NQ+L+D +F++ + + E + ++V
Sbjct: 638 PNAIEHTLQWARDEFEGLFKQPAENVNQYLTD-PKFVERTLRLAGTQPLEVLEAVQRSLV 696
Query: 349 YNIPTSFNDCLFWARKLWQEHFHNNIKQLLHNFPSDADTSRDLPFWSGTKRCPKPIIFDI 528
+P S+ DC+ WA W + NNI+QLLHNFP D TS PFWSG KRCP P+ FD+
Sbjct: 697 LQLPQSWADCVTWACHHWHTQYSNNIRQLLHNFPPDQLTSSGAPFWSGPKRCPHPLTFDV 756
Query: 529 DN 534
N
Sbjct: 757 SN 758
>sp|P22314|UBE1_HUMAN Ubiquitin-activating enzyme E1 (A1S9 protein)
Length = 1058
Score = 221 bits (563), Expect = 9e-58
Identities = 107/182 (58%), Positives = 131/182 (71%), Gaps = 4/182 (2%)
Frame = +1
Query: 1 VEAGQYMDRRCVFYLKPLLESGTLGTKCNVQVVLPHLTESYSSSPDPPEKSIPVCTLKNF 180
V+A YMDRRCV+Y KPLLESGTLGTK NVQVV+P LTESYSSS DPPEKSIP+CTLKNF
Sbjct: 578 VDARMYMDRRCVYYRKPLLESGTLGTKGNVQVVIPFLTESYSSSQDPPEKSIPICTLKNF 637
Query: 181 PYTIEHTIQWARDLFEGLFSQPAASANQFLSDKQRFLDSVSKCHSSDTGEQVS----NIV 348
P IEHT+QWARD FEGLF QPA + NQ+L+D +F++ + + E + ++V
Sbjct: 638 PNAIEHTLQWARDEFEGLFKQPAENVNQYLTD-PKFVERTLRLAGTQPLEVLEAVQRSLV 696
Query: 349 YNIPTSFNDCLFWARKLWQEHFHNNIKQLLHNFPSDADTSRDLPFWSGTKRCPKPIIFDI 528
P ++ DC+ WA W + NNI+QLLHNFP D TS PFWSG KRCP P+ FD+
Sbjct: 697 LQRPQTWADCVTWACHHWHTQYSNNIRQLLHNFPPDQLTSSGAPFWSGPKRCPHPLTFDV 756
Query: 529 DN 534
+N
Sbjct: 757 NN 758
>sp|Q02053|UBE1_MOUSE Ubiquitin-activating enzyme E1 1
Length = 1058
Score = 221 bits (563), Expect = 9e-58
Identities = 106/182 (58%), Positives = 131/182 (71%), Gaps = 4/182 (2%)
Frame = +1
Query: 1 VEAGQYMDRRCVFYLKPLLESGTLGTKCNVQVVLPHLTESYSSSPDPPEKSIPVCTLKNF 180
++A YMDRRCV+Y KPLLESGTLGTK NVQVV+P LTESYSSS DPPEKSIP+CTLKNF
Sbjct: 578 IDARMYMDRRCVYYRKPLLESGTLGTKGNVQVVIPFLTESYSSSQDPPEKSIPICTLKNF 637
Query: 181 PYTIEHTIQWARDLFEGLFSQPAASANQFLSDKQRFLDSVSKCHSSDTGEQVS----NIV 348
P IEHT+QWARD FEGLF QPA + NQ+L+D +F++ + + E + ++V
Sbjct: 638 PNAIEHTLQWARDEFEGLFKQPAENVNQYLTD-SKFVERTLRLAGTQPLEVLEAVQRSLV 696
Query: 349 YNIPTSFNDCLFWARKLWQEHFHNNIKQLLHNFPSDADTSRDLPFWSGTKRCPKPIIFDI 528
P ++ DC+ WA W + NNI+QLLHNFP D TS PFWSG KRCP P+ FD+
Sbjct: 697 LQRPQTWGDCVTWACHHWHTQYCNNIRQLLHNFPPDQLTSSGAPFWSGPKRCPHPLTFDV 756
Query: 529 DN 534
+N
Sbjct: 757 NN 758
>sp|O94609|UBA1_SCHPO Ubiquitin-activating enzyme E1 1 (Poly(A)+ RNA transport protein 3)
Length = 1012
Score = 216 bits (549), Expect = 4e-56
Identities = 111/182 (60%), Positives = 129/182 (70%), Gaps = 4/182 (2%)
Frame = +1
Query: 1 VEAGQYMDRRCVFYLKPLLESGTLGTKCNVQVVLPHLTESYSSSPDPPEKSIPVCTLKNF 180
VEA Y+DRRCVF+ KPLLESGTLGTK N QVV+PHLTESY SS DPPEKS P+CTLKNF
Sbjct: 539 VEARMYVDRRCVFFEKPLLESGTLGTKGNTQVVVPHLTESYGSSQDPPEKSFPICTLKNF 598
Query: 181 PYTIEHTIQWARDLFEGLFSQPAASANQFLSDKQRFLDSVSKCHSSDTGEQVSNI----V 348
P IEHTI WARDLFEGLF QP + N +LS FL++ K SS+ E + NI V
Sbjct: 599 PNRIEHTIAWARDLFEGLFKQPIDNVNMYLS-SPNFLETSLKT-SSNpreVLENIRDYLV 656
Query: 349 YNIPTSFNDCLFWARKLWQEHFHNNIKQLLHNFPSDADTSRDLPFWSGTKRCPKPIIFDI 528
P SF +C+ WAR + + F+NNI+QLL NFP D+ TS PFWSG KR P P+ FDI
Sbjct: 657 TEKPLSFEECIMWARLQFDKFFNNNIQQLLFNFPKDSVTSTGQPFWSGPKRAPTPLSFDI 716
Query: 529 DN 534
N
Sbjct: 717 HN 718
>sp|P22515|UBA1_YEAST Ubiquitin-activating enzyme E1 1
Length = 1024
Score = 199 bits (506), Expect = 4e-51
Identities = 98/180 (54%), Positives = 128/180 (71%), Gaps = 2/180 (1%)
Frame = +1
Query: 1 VEAGQYMDRRCVFYLKPLLESGTLGTKCNVQVVLPHLTESYSSSPDPPEKSIPVCTLKNF 180
V+A Y+DRRCVFY KPLLESGTLGTK N QV++P LTESYSSS DPPEKSIP+CTL++F
Sbjct: 546 VDARTYVDRRCVFYRKPLLESGTLGTKGNTQVIIPRLTESYSSSRDPPEKSIPLCTLRSF 605
Query: 181 PYTIEHTIQWARDLFEGLFSQPAASANQFLSDKQRFLDSVSKCHSSDTG--EQVSNIVYN 354
P I+HTI WA+ LF+G F+ A + N +L+ + F++ K G E +S+ + +
Sbjct: 606 PNKIDHTIAWAKSLFQGYFTDSAENVNMYLT-QPNFVEQTLKQSGDVKGVLESISDSLSS 664
Query: 355 IPTSFNDCLFWARKLWQEHFHNNIKQLLHNFPSDADTSRDLPFWSGTKRCPKPIIFDIDN 534
P +F DC+ WAR +++ F+++IKQLL NFP DA TS PFWSG KR P P+ FDI N
Sbjct: 665 KPHNFEDCIKWARLEFEKKFNHDIKQLLFNFPKDAKTSNGEPFWSGAKRAPTPLEFDIYN 724
>sp|P31255|UBE1Y_MACRU Ubiquitin-activating enzyme E1 Y
Length = 152
Score = 174 bits (442), Expect = 9e-44
Identities = 85/151 (56%), Positives = 107/151 (70%), Gaps = 4/151 (2%)
Frame = +1
Query: 16 YMDRRCVFYLKPLLESGTLGTKCNVQVVLPHLTESYSSSPDPPEKSIPVCTLKNFPYTIE 195
YMDR CV+Y KPLLESGTLGTK N+QVV+P LTESYSSS DPPEKSIP+CTLKNFP IE
Sbjct: 2 YMDRHCVYYRKPLLESGTLGTKGNIQVVIPFLTESYSSSQDPPEKSIPICTLKNFPNAIE 61
Query: 196 HTIQWARDLFEGLFSQPAASANQFLSDKQRFLDSVSKCHSSDTGEQVS----NIVYNIPT 363
HT+QWARD FE LF QPA + NQ+L++ +F++ + + E + ++V P
Sbjct: 62 HTLQWARDEFESLFKQPAENVNQYLTN-PKFVERTLRLGGTQPLEVLEAVHRSLVLQRPH 120
Query: 364 SFNDCLFWARKLWQEHFHNNIKQLLHNFPSD 456
+ DC+ WA W + NNI+QLLHNFP +
Sbjct: 121 DWADCVTWACLHWHSQYANNIRQLLHNFPPE 151
>sp|P31252|UBE13_WHEAT Ubiquitin-activating enzyme E1 3
Length = 1053
Score = 173 bits (439), Expect = 2e-43
Identities = 79/178 (44%), Positives = 114/178 (64%), Gaps = 4/178 (2%)
Frame = +1
Query: 1 VEAGQYMDRRCVFYLKPLLESGTLGTKCNVQVVLPHLTESYSSSPDPPEKSIPVCTLKNF 180
V A YMD RC+++ KPLLESGTLG KCN+Q+V+PHLTE+Y +S DPPEK P+CT+ +F
Sbjct: 575 VNARMYMDMRCLYFQKPLLESGTLGAKCNIQMVIPHLTENYGASRDPPEKQAPMCTVHSF 634
Query: 181 PYTIEHTIQWARDLFEGLFSQPAASANQFLSDKQRFLDSVSKCHSSDTGEQVSNIVYNIP 360
P+ I+H + WAR FEGL + N FLS+ ++ ++ K + E + + +
Sbjct: 635 PHNIDHCLTWARSEFEGLLEKTPNEVNSFLSNPAQYAAAMRKAGDAQARELLERVSECLN 694
Query: 361 ----TSFNDCLFWARKLWQEHFHNNIKQLLHNFPSDADTSRDLPFWSGTKRCPKPIIF 522
++F+DC+ WAR ++++F N +KQL FP DA TS PFWS KR P+ + F
Sbjct: 695 KDRCSTFDDCISWARLKFEDYFSNRVKQLTFTFPEDAATSMGAPFWSAPKRFPRALQF 752
>sp|P20973|UBE11_WHEAT Ubiquitin-activating enzyme E1 1
Length = 1051
Score = 171 bits (433), Expect = 1e-42
Identities = 77/178 (43%), Positives = 111/178 (62%), Gaps = 4/178 (2%)
Frame = +1
Query: 1 VEAGQYMDRRCVFYLKPLLESGTLGTKCNVQVVLPHLTESYSSSPDPPEKSIPVCTLKNF 180
V A Y+D RCV++ KPLLESGTLG KCN Q+V+PHLTE+Y +S DPPEK P+CT+ +F
Sbjct: 572 VTARMYIDSRCVYFQKPLLESGTLGAKCNTQMVIPHLTENYGASRDPPEKQAPMCTVHSF 631
Query: 181 PYTIEHTIQWARDLFEGLFSQPAASANQFLSDKQRFLDSVSKCHSSDTGEQVSNIVYNIP 360
P+ I+H + WAR FEGL + N FLS+ ++ + + +Q+ ++ +
Sbjct: 632 PHNIDHCLTWARSEFEGLLEKTPTEVNAFLSNPTTYISAARTAGDAQARDQLERVIECLD 691
Query: 361 ----TSFNDCLFWARKLWQEHFHNNIKQLLHNFPSDADTSRDLPFWSGTKRCPKPIIF 522
+F D + WAR ++++F N +KQL FP D+ TS PFWS KR P+P+ F
Sbjct: 692 RDKCETFQDSITWARLKFEDYFSNRVKQLTFTFPEDSMTSSGAPFWSAPKRFPRPVEF 749
>sp|P31251|UBE12_WHEAT Ubiquitin-activating enzyme E1 2
Length = 1051
Score = 171 bits (433), Expect = 1e-42
Identities = 77/178 (43%), Positives = 111/178 (62%), Gaps = 4/178 (2%)
Frame = +1
Query: 1 VEAGQYMDRRCVFYLKPLLESGTLGTKCNVQVVLPHLTESYSSSPDPPEKSIPVCTLKNF 180
V A Y+D RCV++ KPLLESGTLG KCN Q+V+PHLTE+Y +S DPPEK P+CT+ +F
Sbjct: 572 VTARMYIDSRCVYFQKPLLESGTLGAKCNTQMVIPHLTENYGASRDPPEKQAPMCTVHSF 631
Query: 181 PYTIEHTIQWARDLFEGLFSQPAASANQFLSDKQRFLDSVSKCHSSDTGEQVSNIVYNIP 360
P+ I+H + WAR FEGL + N FLS+ ++ + + +Q+ ++ +
Sbjct: 632 PHNIDHCLTWARSEFEGLLEKTPTEVNAFLSNPTTYISAARTAGDAQARDQLERVIECLD 691
Query: 361 ----TSFNDCLFWARKLWQEHFHNNIKQLLHNFPSDADTSRDLPFWSGTKRCPKPIIF 522
+F D + WAR ++++F N +KQL FP D+ TS PFWS KR P+P+ F
Sbjct: 692 RDKCETFQDSITWARLKFEDYFSNRVKQLTFTFPEDSMTSSGAPFWSAPKRFPRPVEF 749
>sp|P31253|UBE1X_MOUSE Ubiquitin-activating enzyme E1 X
Length = 450
Score = 164 bits (415), Expect = 1e-40
Identities = 78/145 (53%), Positives = 99/145 (68%), Gaps = 4/145 (2%)
Frame = +1
Query: 112 TESYSSSPDPPEKSIPVCTLKNFPYTIEHTIQWARDLFEGLFSQPAASANQFLSDKQRFL 291
TESYSSS DPPEKSIP+CTLKNFP IEHT+QWARD FEGLF QPA + NQ+L+D +F+
Sbjct: 1 TESYSSSQDPPEKSIPICTLKNFPNAIEHTLQWARDEFEGLFKQPAENVNQYLTD-SKFV 59
Query: 292 DSVSKCHSSDTGEQVS----NIVYNIPTSFNDCLFWARKLWQEHFHNNIKQLLHNFPSDA 459
+ + + E + ++V P ++ DC+ WA W + NNI+QLLHNFP D
Sbjct: 60 ERTLRLAGTQPLEVLEAVQRSLVLQRPQTWGDCVTWACHHWHTQYCNNIRQLLHNFPPDQ 119
Query: 460 DTSRDLPFWSGTKRCPKPIIFDIDN 534
TS PFWSG KRCP P+ FD++N
Sbjct: 120 LTSSGAPFWSGPKRCPHPLTFDVNN 144
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 72,171,707
Number of Sequences: 369166
Number of extensions: 1552207
Number of successful extensions: 3817
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 3681
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3794
length of database: 68,354,980
effective HSP length: 103
effective length of database: 49,327,275
effective search space used: 3699545625
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)