Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= DrC_02815
(597 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|O75689|CENA1_HUMAN Centaurin-alpha 1 (Putative MAPK-acti... 47 3e-05
sp|Q7TQG1|PLEA6_MOUSE Pleckstrin homology domain-containing... 42 0.001
sp|Q9Y2H5|PLEA6_HUMAN Pleckstrin homology domain-containing... 40 0.003
sp|Q9NPF8|CENA2_HUMAN Centaurin-alpha 2 40 0.006
sp|Q9JK15|CENA2_RAT Centaurin-alpha 2 38 0.022
sp|Q9H4M7|PLEA4_HUMAN Pleckstrin homology domain-containing... 37 0.038
sp|P60669|PLEA4_RAT Pleckstrin homology domain-containing p... 37 0.038
sp|Q8VC98|PLEA4_MOUSE Pleckstrin homology domain-containing... 37 0.038
sp|Q8R2V5|CENA2_MOUSE Centaurin-alpha 2 37 0.049
sp|Q9HAU0|PLEA5_HUMAN Pleckstrin homology domain-containing... 32 1.2
>sp|O75689|CENA1_HUMAN Centaurin-alpha 1 (Putative MAPK-activating protein PM25)
Length = 374
Score = 47.4 bits (111), Expect = 3e-05
Identities = 23/58 (39%), Positives = 33/58 (56%)
Frame = +1
Query: 418 LARDLTLDITMSGWMYKTGSQLTEQWQKRWCVLLGRRLLYSSGPLSPCGRGEIVIGER 591
L L+ + G+M KTG + TE ++KRW + RRL+Y PL RGE+ IG +
Sbjct: 245 LVPKLSRNYLKEGYMEKTGPKQTEGFRKRWFTMDDRRLMYFKDPLDAFARGEVFIGSK 302
>sp|Q7TQG1|PLEA6_MOUSE Pleckstrin homology domain-containing protein family A member 6
(Phosphoinositol 3-phosphate-binding protein 3) (PEPP-3)
Length = 1173
Score = 42.0 bits (97), Expect = 0.001
Identities = 17/40 (42%), Positives = 24/40 (60%)
Frame = +1
Query: 418 LARDLTLDITMSGWMYKTGSQLTEQWQKRWCVLLGRRLLY 537
+ R+ +T +GW+YK S +QW KRW VL+ R L Y
Sbjct: 52 MKRNPNAPVTKAGWLYKQASSGVKQWNKRWFVLVDRCLFY 91
>sp|Q9Y2H5|PLEA6_HUMAN Pleckstrin homology domain-containing protein family A member 6
(Phosphoinositol 3-phosphate-binding protein 3) (PEPP-3)
Length = 1048
Score = 40.4 bits (93), Expect = 0.003
Identities = 16/40 (40%), Positives = 24/40 (60%)
Frame = +1
Query: 418 LARDLTLDITMSGWMYKTGSQLTEQWQKRWCVLLGRRLLY 537
+ R+ +T +GW++K S +QW KRW VL+ R L Y
Sbjct: 52 MKRNPNAPVTKAGWLFKQASSGVKQWNKRWFVLVDRCLFY 91
>sp|Q9NPF8|CENA2_HUMAN Centaurin-alpha 2
Length = 381
Score = 39.7 bits (91), Expect = 0.006
Identities = 22/63 (34%), Positives = 34/63 (53%), Gaps = 2/63 (3%)
Frame = +1
Query: 415 QLARDLTLDITMSGWMYKTGSQLTEQWQKRWCVL--LGRRLLYSSGPLSPCGRGEIVIGE 588
+L LT + G+M KTG + E ++KRW L RRLLY PL +G++ +G
Sbjct: 247 ELVPFLTRNYLKQGFMEKTGPKQKEPFKKRWFALDCHERRLLYYKNPLDAFEQGQVFLGN 306
Query: 589 RSR 597
+ +
Sbjct: 307 KEQ 309
>sp|Q9JK15|CENA2_RAT Centaurin-alpha 2
Length = 376
Score = 37.7 bits (86), Expect = 0.022
Identities = 20/58 (34%), Positives = 31/58 (53%), Gaps = 2/58 (3%)
Frame = +1
Query: 430 LTLDITMSGWMYKTGSQLTEQWQKRWCVL--LGRRLLYSSGPLSPCGRGEIVIGERSR 597
+T + G+M KTG + E ++KRW L RRLLY PL +G++ +G +
Sbjct: 251 ITRNYLKQGFMEKTGPKHREPFKKRWFALDPQERRLLYYKNPLDAFEQGQVFLGSNEQ 308
>sp|Q9H4M7|PLEA4_HUMAN Pleckstrin homology domain-containing protein family A member 4
(Phosphoinositol 3-phosphate binding protein 1) (PEPP-1)
Length = 779
Score = 37.0 bits (84), Expect = 0.038
Identities = 16/40 (40%), Positives = 22/40 (55%)
Frame = +1
Query: 418 LARDLTLDITMSGWMYKTGSQLTEQWQKRWCVLLGRRLLY 537
L RD L + + GW++K S W++RW VL G L Y
Sbjct: 47 LRRDPNLPVHIRGWLHKQDSSGLRLWKRRWFVLSGHCLFY 86
>sp|P60669|PLEA4_RAT Pleckstrin homology domain-containing protein family A member 4
(Phosphoinositol 3-phosphate binding protein 1) (PEPP-1)
Length = 779
Score = 37.0 bits (84), Expect = 0.038
Identities = 16/40 (40%), Positives = 22/40 (55%)
Frame = +1
Query: 418 LARDLTLDITMSGWMYKTGSQLTEQWQKRWCVLLGRRLLY 537
L RD L + + GW++K S W++RW VL G L Y
Sbjct: 47 LRRDPNLPVHIRGWLHKQDSSGLRLWKRRWFVLSGHCLFY 86
>sp|Q8VC98|PLEA4_MOUSE Pleckstrin homology domain-containing protein family A member 4
(Phosphoinositol 3-phosphate binding protein 1) (PEPP-1)
Length = 588
Score = 37.0 bits (84), Expect = 0.038
Identities = 16/40 (40%), Positives = 22/40 (55%)
Frame = +1
Query: 418 LARDLTLDITMSGWMYKTGSQLTEQWQKRWCVLLGRRLLY 537
L RD L + + GW++K S W++RW VL G L Y
Sbjct: 47 LRRDPNLPVHIRGWLHKQDSSGLRLWKRRWFVLSGHCLFY 86
>sp|Q8R2V5|CENA2_MOUSE Centaurin-alpha 2
Length = 381
Score = 36.6 bits (83), Expect = 0.049
Identities = 20/58 (34%), Positives = 30/58 (51%), Gaps = 2/58 (3%)
Frame = +1
Query: 430 LTLDITMSGWMYKTGSQLTEQWQKRWCVL--LGRRLLYSSGPLSPCGRGEIVIGERSR 597
+T + G+M KTG + E ++KRW L RRLLY PL G++ +G +
Sbjct: 252 ITRNYLKQGFMEKTGPKHREPFKKRWFALDPQERRLLYYKNPLDAFELGQVFLGSNEQ 309
>sp|Q9HAU0|PLEA5_HUMAN Pleckstrin homology domain-containing protein family A member 5
(Phosphoinositol 3-phosphate-binding protein 2) (PEPP-2)
Length = 1116
Score = 32.0 bits (71), Expect = 1.2
Identities = 14/40 (35%), Positives = 20/40 (50%)
Frame = +1
Query: 418 LARDLTLDITMSGWMYKTGSQLTEQWQKRWCVLLGRRLLY 537
+ R+ + GW+YK S + W+KRW VL L Y
Sbjct: 162 IKRNPNAPVVRRGWLYKQDSTGMKLWKKRWFVLSDLCLFY 201
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 63,001,382
Number of Sequences: 369166
Number of extensions: 1120618
Number of successful extensions: 1868
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 1819
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 1868
length of database: 68,354,980
effective HSP length: 105
effective length of database: 48,957,805
effective search space used: 4553075865
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)